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MCL coexpression mm9:1420: Difference between revisions

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{{MCL_coexpression_mm9
{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=GO:0001665;alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity;0.0197130614772321;50935!GO:0001574;ganglioside biosynthetic process;0.0197130614772321;50935!GO:0006688;glycosphingolipid biosynthetic process;0.0197130614772321;50935!GO:0001573;ganglioside metabolic process;0.0197130614772321;50935!GO:0030866;cortical actin cytoskeleton organization and biogenesis;0.0197130614772321;13821!GO:0009247;glycolipid biosynthetic process;0.0197130614772321;50935!GO:0030865;cortical cytoskeleton organization and biogenesis;0.0197130614772321;13821!GO:0006687;glycosphingolipid metabolic process;0.0197130614772321;50935!GO:0030148;sphingolipid biosynthetic process;0.0252244233060822;50935!GO:0006664;glycolipid metabolic process;0.0252244233060822;50935!GO:0008373;sialyltransferase activity;0.0286578341591222;50935!GO:0006672;ceramide metabolic process;0.0302051664628912;50935!GO:0046519;sphingoid metabolic process;0.0303028649509956;50935!GO:0006665;sphingolipid metabolic process;0.0472284331056137;50935!
|gostat_on_MCL_coexpression=GO:0001665;alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity;0.0197130614772321;50935!GO:0001574;ganglioside biosynthetic process;0.0197130614772321;50935!GO:0006688;glycosphingolipid biosynthetic process;0.0197130614772321;50935!GO:0001573;ganglioside metabolic process;0.0197130614772321;50935!GO:0030866;cortical actin cytoskeleton organization and biogenesis;0.0197130614772321;13821!GO:0009247;glycolipid biosynthetic process;0.0197130614772321;50935!GO:0030865;cortical cytoskeleton organization and biogenesis;0.0197130614772321;13821!GO:0006687;glycosphingolipid metabolic process;0.0197130614772321;50935!GO:0030148;sphingolipid biosynthetic process;0.0252244233060822;50935!GO:0006664;glycolipid metabolic process;0.0252244233060822;50935!GO:0008373;sialyltransferase activity;0.0286578341591222;50935!GO:0006672;ceramide metabolic process;0.0302051664628912;50935!GO:0046519;sphingoid metabolic process;0.0303028649509956;50935!GO:0006665;sphingolipid metabolic process;0.0472284331056137;50935!
}}
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Revision as of 12:57, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr19:5424822..5424845,-p3@Drap1
Mm9::chr2:156301447..156301474,+p5@Epb4.1l1
Mm9::chr2:156301539..156301570,+p4@Epb4.1l1
Mm9::chr2:156301580..156301598,+p3@Epb4.1l1
Mm9::chr2:32462499..32462577,+p1@St6galnac6
Mm9::chr8:73397376..73397400,-p1@Ccdc124


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0001665alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity0.0197130614772321
GO:0001574ganglioside biosynthetic process0.0197130614772321
GO:0006688glycosphingolipid biosynthetic process0.0197130614772321
GO:0001573ganglioside metabolic process0.0197130614772321
GO:0030866cortical actin cytoskeleton organization and biogenesis0.0197130614772321
GO:0009247glycolipid biosynthetic process0.0197130614772321
GO:0030865cortical cytoskeleton organization and biogenesis0.0197130614772321
GO:0006687glycosphingolipid metabolic process0.0197130614772321
GO:0030148sphingolipid biosynthetic process0.0252244233060822
GO:0006664glycolipid metabolic process0.0252244233060822
GO:0008373sialyltransferase activity0.0286578341591222
GO:0006672ceramide metabolic process0.0302051664628912
GO:0046519sphingoid metabolic process0.0303028649509956
GO:0006665sphingolipid metabolic process0.0472284331056137



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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