MCL coexpression mm9:1050

Phase1 CAGE Peaks

	Short description
Mm9::chr10:97110040..97110070,+	p2@Epyc
Mm9::chr14:80061897..80061908,-	p3@Lect1
Mm9::chr14:80061914..80061919,-	p4@Lect1
Mm9::chr14:80061926..80061952,-	p2@Lect1
Mm9::chr14:80061955..80061980,-	p1@Lect1
Mm9::chr2:180332924..180332931,+	p2@Col9a3
Mm9::chr4:120712161..120712285,+	p1@Col9a2

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0030934	anchoring collagen	7.68413969194452e-07
GO:0005593	FACIT collagen	7.68413969194452e-07
GO:0005594	collagen type IX	7.68413969194452e-07
GO:0005578	proteinaceous extracellular matrix	0.000186816617471087
GO:0030020	extracellular matrix structural constituent conferring tensile strength	0.000186816617471087
GO:0005581	collagen	0.000228052395601774
GO:0005201	extracellular matrix structural constituent	0.000580429918189773
GO:0044420	extracellular matrix part	0.00119830147109974
GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	0.00155834352952635
GO:0001501	skeletal development	0.00366562736125257
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	0.00637294626688134
GO:0048010	vascular endothelial growth factor receptor signaling pathway	0.0163451333037402
GO:0016525	negative regulation of angiogenesis	0.0172403831278707
GO:0005615	extracellular space	0.0211013759293603
GO:0044421	extracellular region part	0.0224121950137161
GO:0022610	biological adhesion	0.0224121950137161
GO:0007155	cell adhesion	0.0224121950137161
GO:0045765	regulation of angiogenesis	0.023319499887863
GO:0051216	cartilage development	0.0352951820224402
GO:0006817	phosphate transport	0.046729817468914

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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