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MCL coexpression mm9:553: Difference between revisions

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{{MCL_coexpression_mm9
{{MCL_coexpression_mm9
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|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0.864928731305936,0.194002013165964,0.286963248752788,0.180026585552633,0.145774498636601,0.552426178402832,0.526384625876103,0.22173221893217,0.206130935280821,0,0.80365215003912,0.820968961631894,0.719654112820952,0.0682179984609265,0.0411126530948397,0,0.120568945209029,0.0896964873768703,0,0,0,0,0.0976147801771522,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.5305967864214,0.236880264493592,0.37002711790928,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0570741246689917,0,0,0,0,0,0,0,0,0,0,0.0893284091371433,0.790901162787453,0.0601091194109999,0,0,0,0,0,0,0,0.110319863569628,0,0,0.0866592903778752,0,0,0,0,0.098801861608942,0.0491463288895459,0,0,0,0,0,0,0,0,0,0,0.137740408373976,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0861996515928926,0.0546921007390138,0,0,0,0.101901855392646,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0788703512227347,0,0,0,0,0,0,0,0.0573773365933198,0,0.0505333231410966,0,0,0,0,0,0,0,0.109813392994768,0.0652566657696677,0,0,0,0,0,0.0716601710131013,0,0.284152233790825,0,0,0,0,0,0,0,0.119015009568782,0.086880916817156,0.0642538110976656,0.17364944681578,0.128841727545421,0.156533152932051,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.374192211594598,0,0.0737896374598673,0.243899288077882,0.374187666887789,0.415215017786867,0.0681778550615498,0.107177024667156,0.0562185712770556,0,0,0,0,0,0.0857765460992942,0,0.034489466458534,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.289596390303526,0,0.0811390825906054,0.0530480122014902,0.132916844396872,0.145309149361067,0.170491067385816,0.159286971335735,0.207930782042359,0.206732655436992,0.205463431268847,0.172395483787789,0.223621276793701,0.259626919190674,0,0,0,0,0,0.0747003483965965,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0269518943326477,0.0242538736058389,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0905641158318875
|gostat_on_MCL_coexpression=GO:0042270;protection from natural killer cell mediated cytotoxicity;0.0183938166882631;93694!GO:0045953;negative regulation of natural killer cell mediated cytotoxicity;0.0183938166882631;93694!GO:0001911;negative regulation of leukocyte mediated cytotoxicity;0.0183938166882631;93694!GO:0045671;negative regulation of osteoclast differentiation;0.0183938166882631;93694!GO:0046703;natural killer cell lectin-like receptor binding;0.0183938166882631;93694!GO:0002762;negative regulation of myeloid leukocyte differentiation;0.0183938166882631;93694!GO:0003841;1-acylglycerol-3-phosphate O-acyltransferase activity;0.0183938166882631;28169!GO:0042269;regulation of natural killer cell mediated cytotoxicity;0.0183938166882631;93694!GO:0006955;immune response;0.0183938166882631;93694,229898!GO:0016411;acylglycerol O-acyltransferase activity;0.0183938166882631;28169!GO:0042267;natural killer cell mediated cytotoxicity;0.0183938166882631;93694!GO:0001910;regulation of leukocyte mediated cytotoxicity;0.0183938166882631;93694!GO:0045670;regulation of osteoclast differentiation;0.0183938166882631;93694!GO:0031341;regulation of cell killing;0.0183938166882631;93694!GO:0002228;natural killer cell mediated immunity;0.0183938166882631;93694!GO:0002761;regulation of myeloid leukocyte differentiation;0.0202254373957362;93694!GO:0045638;negative regulation of myeloid cell differentiation;0.0202254373957362;93694!GO:0030316;osteoclast differentiation;0.0202254373957362;93694!GO:0001909;leukocyte mediated cytotoxicity;0.0202254373957362;93694!GO:0001906;cell killing;0.0202254373957362;93694!GO:0002376;immune system process;0.0240773804173256;93694,229898!GO:0008374;O-acyltransferase activity;0.0250618638310431;28169!GO:0045637;regulation of myeloid cell differentiation;0.027959922163863;93694!GO:0002573;myeloid leukocyte differentiation;0.0306143784178908;93694!GO:0008654;phospholipid biosynthetic process;0.0425731710633747;28169!
|gostat_on_MCL_coexpression=GO:0042270;protection from natural killer cell mediated cytotoxicity;0.0183938166882631;93694!GO:0045953;negative regulation of natural killer cell mediated cytotoxicity;0.0183938166882631;93694!GO:0001911;negative regulation of leukocyte mediated cytotoxicity;0.0183938166882631;93694!GO:0045671;negative regulation of osteoclast differentiation;0.0183938166882631;93694!GO:0046703;natural killer cell lectin-like receptor binding;0.0183938166882631;93694!GO:0002762;negative regulation of myeloid leukocyte differentiation;0.0183938166882631;93694!GO:0003841;1-acylglycerol-3-phosphate O-acyltransferase activity;0.0183938166882631;28169!GO:0042269;regulation of natural killer cell mediated cytotoxicity;0.0183938166882631;93694!GO:0006955;immune response;0.0183938166882631;93694,229898!GO:0016411;acylglycerol O-acyltransferase activity;0.0183938166882631;28169!GO:0042267;natural killer cell mediated cytotoxicity;0.0183938166882631;93694!GO:0001910;regulation of leukocyte mediated cytotoxicity;0.0183938166882631;93694!GO:0045670;regulation of osteoclast differentiation;0.0183938166882631;93694!GO:0031341;regulation of cell killing;0.0183938166882631;93694!GO:0002228;natural killer cell mediated immunity;0.0183938166882631;93694!GO:0002761;regulation of myeloid leukocyte differentiation;0.0202254373957362;93694!GO:0045638;negative regulation of myeloid cell differentiation;0.0202254373957362;93694!GO:0030316;osteoclast differentiation;0.0202254373957362;93694!GO:0001909;leukocyte mediated cytotoxicity;0.0202254373957362;93694!GO:0001906;cell killing;0.0202254373957362;93694!GO:0002376;immune system process;0.0240773804173256;93694,229898!GO:0008374;O-acyltransferase activity;0.0250618638310431;28169!GO:0045637;regulation of myeloid cell differentiation;0.027959922163863;93694!GO:0002573;myeloid leukocyte differentiation;0.0306143784178908;93694!GO:0008654;phospholipid biosynthetic process;0.0425731710633747;28169!
}}
}}

Revision as of 12:43, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr10:7552113..7552123,+p4@Zc3h12d
Mm9::chr10:7552124..7552165,+p2@Zc3h12d
Mm9::chr10:77761001..77761011,-p23@Agpat3
Mm9::chr12:102245868..102245883,+p@chr12:102245868..102245883
+
Mm9::chr14:59879040..59879065,-p1@Gm6904
Mm9::chr15:97191565..97191586,+p6@Fam113b
Mm9::chr17:27479398..27479415,+p1@ENSMUST00000151398
p1@uc012anv.1
Mm9::chr1:165993128..165993139,-p@chr1:165993128..165993139
-
Mm9::chr3:142159736..142159753,+p2@Gbp5
Mm9::chr3:142159755..142159768,+p5@Gbp5
Mm9::chr6:129130657..129130674,+p2@Clec2d
Mm9::chr6:99255980..99255988,+p@chr6:99255980..99255988
+
Mm9::chr7:25677212..25677252,-p@chr7:25677212..25677252
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0042270protection from natural killer cell mediated cytotoxicity0.0183938166882631
GO:0045953negative regulation of natural killer cell mediated cytotoxicity0.0183938166882631
GO:0001911negative regulation of leukocyte mediated cytotoxicity0.0183938166882631
GO:0045671negative regulation of osteoclast differentiation0.0183938166882631
GO:0046703natural killer cell lectin-like receptor binding0.0183938166882631
GO:0002762negative regulation of myeloid leukocyte differentiation0.0183938166882631
GO:00038411-acylglycerol-3-phosphate O-acyltransferase activity0.0183938166882631
GO:0042269regulation of natural killer cell mediated cytotoxicity0.0183938166882631
GO:0006955immune response0.0183938166882631
GO:0016411acylglycerol O-acyltransferase activity0.0183938166882631
GO:0042267natural killer cell mediated cytotoxicity0.0183938166882631
GO:0001910regulation of leukocyte mediated cytotoxicity0.0183938166882631
GO:0045670regulation of osteoclast differentiation0.0183938166882631
GO:0031341regulation of cell killing0.0183938166882631
GO:0002228natural killer cell mediated immunity0.0183938166882631
GO:0002761regulation of myeloid leukocyte differentiation0.0202254373957362
GO:0045638negative regulation of myeloid cell differentiation0.0202254373957362
GO:0030316osteoclast differentiation0.0202254373957362
GO:0001909leukocyte mediated cytotoxicity0.0202254373957362
GO:0001906cell killing0.0202254373957362
GO:0002376immune system process0.0240773804173256
GO:0008374O-acyltransferase activity0.0250618638310431
GO:0045637regulation of myeloid cell differentiation0.027959922163863
GO:0002573myeloid leukocyte differentiation0.0306143784178908
GO:0008654phospholipid biosynthetic process0.0425731710633747



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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