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{{Coexpression_clusters
{{Coexpression_clusters
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|full_id=C926_Chondrocyte_Adipocyte_tenocyte_Wilms_Preadipocyte_Hair_Fibroblast
|full_id=C926_Chondrocyte_Adipocyte_tenocyte_Wilms_Preadipocyte_Hair_Fibroblast
|id=C926
|id=C926

Revision as of 18:42, 12 September 2012


Full id: C926_Chondrocyte_Adipocyte_tenocyte_Wilms_Preadipocyte_Hair_Fibroblast



Phase1 CAGE Peaks

Hg19::chr1:103354468..103354475,-p@chr1:103354468..103354475
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Hg19::chr1:103461440..103461473,-p@chr1:103461440..103461473
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Hg19::chr1:103474065..103474069,-p8@COL11A1
Hg19::chr1:103491786..103491795,-p@chr1:103491786..103491795
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Hg19::chr1:103491818..103491832,-p@chr1:103491818..103491832
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Hg19::chr1:103491839..103491850,-p@chr1:103491839..103491850
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Hg19::chr1:103491869..103491878,-p@chr1:103491869..103491878
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Hg19::chr1:103496790..103496803,-p5@COL11A1
Hg19::chr1:103544421..103544430,-p@chr1:103544421..103544430
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
organism subdivision1.50e-11365
central nervous system1.99e-1182
regional part of nervous system5.44e-1194
nervous system5.44e-1194
neural plate1.26e-1086
presumptive neural plate1.26e-1086
pre-chordal neural plate1.98e-1061
head2.90e-10123
neurectoderm3.67e-1090
anterior region of body4.72e-10129
craniocervical region4.72e-10129
regional part of brain5.42e-1059
pigment epithelium of eye6.61e-1011
brain8.72e-1069
future brain8.72e-1069
vasculature of head1.28e-0811
vasculature of organ1.28e-0811
ectoderm-derived structure7.20e-08169
neural tube9.86e-0857
neural rod9.86e-0857
future spinal cord9.86e-0857
neural keel9.86e-0857
ectoderm1.10e-07173
presumptive ectoderm1.10e-07173
omentum2.44e-076
peritoneum2.44e-076
abdominal cavity2.44e-076
visceral peritoneum2.44e-076
gray matter5.29e-0734
brain grey matter5.29e-0734
telencephalon8.85e-0734


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.