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|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0000073!6.88e-33!94;UBERON:0001016!6.88e-33!94;UBERON:0005743!6.56e-32!86;UBERON:0001017!3.36e-31!82;UBERON:0000119!2.76e-29!312;UBERON:0000483!4.03e-29!309;UBERON:0003075!8.94e-29!86;UBERON:0007284!8.94e-29!86;UBERON:0002346!1.07e-27!90;UBERON:0001049!1.74e-27!57;UBERON:0005068!1.74e-27!57;UBERON:0006241!1.74e-27!57;UBERON:0007135!1.74e-27!57;UBERON:0000955!5.91e-26!69;UBERON:0006238!5.91e-26!69;UBERON:0002616!1.09e-25!59;UBERON:0000025!3.33e-24!194;UBERON:0002780!4.13e-22!41;UBERON:0001890!4.13e-22!41;UBERON:0006240!4.13e-22!41;UBERON:0003056!5.08e-22!61;UBERON:0004121!5.74e-22!169;UBERON:0003080!7.20e-22!42;UBERON:0000924!1.33e-21!173;UBERON:0006601!1.33e-21!173;UBERON:0004111!2.43e-21!241;UBERON:0002020!1.70e-19!34;UBERON:0003528!1.70e-19!34;UBERON:0001893!2.06e-19!34;UBERON:0000033!4.23e-19!123;UBERON:0001869!5.41e-19!32;UBERON:0000153!8.04e-19!129;UBERON:0007811!8.04e-19!129;UBERON:0002791!1.00e-18!33;UBERON:0000477!2.08e-18!286;UBERON:0000475!2.80e-17!365;UBERON:0002049!1.40e-16!79;UBERON:0007798!1.40e-16!79;UBERON:0007023!1.73e-16!115;UBERON:0001981!4.98e-16!60;UBERON:0007500!4.98e-16!60;UBERON:0004537!4.98e-16!60;UBERON:0006965!4.98e-16!60;UBERON:0001009!2.48e-15!113;UBERON:0000055!3.15e-15!69;UBERON:0004872!5.52e-15!84;UBERON:0000956!6.61e-15!25;UBERON:0000203!6.61e-15!25;UBERON:0002619!7.27e-15!22;UBERON:0004535!5.48e-14!110;UBERON:0001950!1.07e-13!20;UBERON:0000481!2.44e-13!347;UBERON:0001637!2.89e-13!42;UBERON:0003509!2.89e-13!42;UBERON:0004572!2.89e-13!42;UBERON:0001134!2.90e-12!61;UBERON:0002036!2.90e-12!61;UBERON:0003082!2.90e-12!61;UBERON:0002385!1.19e-11!63;UBERON:0001015!1.19e-11!63;UBERON:0000383!1.19e-11!63;UBERON:0000468!1.90e-11!659;UBERON:0004290!4.88e-11!70;UBERON:0000480!3.78e-10!626;UBERON:0000922!4.11e-10!612;UBERON:0000914!4.38e-10!83;UBERON:0002329!4.38e-10!83;UBERON:0003077!4.38e-10!83;UBERON:0003059!4.38e-10!83;UBERON:0007282!4.38e-10!83;UBERON:0009618!4.38e-10!83;UBERON:0007285!4.38e-10!83;UBERON:0000467!4.79e-10!625;UBERON:0004573!5.96e-10!33;UBERON:0004571!5.96e-10!33;UBERON:0002050!1.69e-08!605;UBERON:0005423!1.69e-08!605;UBERON:0000486!2.40e-08!82;UBERON:0000923!2.90e-08!604;UBERON:0005291!2.90e-08!604;UBERON:0006598!2.90e-08!604;UBERON:0002532!2.90e-08!604;UBERON:0000064!3.61e-08!219;UBERON:0000947!1.24e-07!21;UBERON:0010191!1.24e-07!21;UBERON:0000490!1.96e-07!138;UBERON:0003076!7.35e-07!15;UBERON:0003057!7.35e-07!15
|ontology_enrichment_uberon=UBERON:0000073!6.88e-33!94;UBERON:0001016!6.88e-33!94;UBERON:0005743!6.56e-32!86;UBERON:0001017!3.36e-31!82;UBERON:0000119!2.76e-29!312;UBERON:0000483!4.03e-29!309;UBERON:0003075!8.94e-29!86;UBERON:0007284!8.94e-29!86;UBERON:0002346!1.07e-27!90;UBERON:0001049!1.74e-27!57;UBERON:0005068!1.74e-27!57;UBERON:0006241!1.74e-27!57;UBERON:0007135!1.74e-27!57;UBERON:0000955!5.91e-26!69;UBERON:0006238!5.91e-26!69;UBERON:0002616!1.09e-25!59;UBERON:0000025!3.33e-24!194;UBERON:0002780!4.13e-22!41;UBERON:0001890!4.13e-22!41;UBERON:0006240!4.13e-22!41;UBERON:0003056!5.08e-22!61;UBERON:0004121!5.74e-22!169;UBERON:0003080!7.20e-22!42;UBERON:0000924!1.33e-21!173;UBERON:0006601!1.33e-21!173;UBERON:0004111!2.43e-21!241;UBERON:0002020!1.70e-19!34;UBERON:0003528!1.70e-19!34;UBERON:0001893!2.06e-19!34;UBERON:0000033!4.23e-19!123;UBERON:0001869!5.41e-19!32;UBERON:0000153!8.04e-19!129;UBERON:0007811!8.04e-19!129;UBERON:0002791!1.00e-18!33;UBERON:0000477!2.08e-18!286;UBERON:0000475!2.80e-17!365;UBERON:0002049!1.40e-16!79;UBERON:0007798!1.40e-16!79;UBERON:0007023!1.73e-16!115;UBERON:0001981!4.98e-16!60;UBERON:0007500!4.98e-16!60;UBERON:0004537!4.98e-16!60;UBERON:0006965!4.98e-16!60;UBERON:0001009!2.48e-15!113;UBERON:0000055!3.15e-15!69;UBERON:0004872!5.52e-15!84;UBERON:0000956!6.61e-15!25;UBERON:0000203!6.61e-15!25;UBERON:0002619!7.27e-15!22;UBERON:0004535!5.48e-14!110;UBERON:0001950!1.07e-13!20;UBERON:0000481!2.44e-13!347;UBERON:0001637!2.89e-13!42;UBERON:0003509!2.89e-13!42;UBERON:0004572!2.89e-13!42;UBERON:0001134!2.90e-12!61;UBERON:0002036!2.90e-12!61;UBERON:0003082!2.90e-12!61;UBERON:0002385!1.19e-11!63;UBERON:0001015!1.19e-11!63;UBERON:0000383!1.19e-11!63;UBERON:0000468!1.90e-11!659;UBERON:0004290!4.88e-11!70;UBERON:0000480!3.78e-10!626;UBERON:0000922!4.11e-10!612;UBERON:0000914!4.38e-10!83;UBERON:0002329!4.38e-10!83;UBERON:0003077!4.38e-10!83;UBERON:0003059!4.38e-10!83;UBERON:0007282!4.38e-10!83;UBERON:0009618!4.38e-10!83;UBERON:0007285!4.38e-10!83;UBERON:0000467!4.79e-10!625;UBERON:0004573!5.96e-10!33;UBERON:0004571!5.96e-10!33;UBERON:0002050!1.69e-08!605;UBERON:0005423!1.69e-08!605;UBERON:0000486!2.40e-08!82;UBERON:0000923!2.90e-08!604;UBERON:0005291!2.90e-08!604;UBERON:0006598!2.90e-08!604;UBERON:0002532!2.90e-08!604;UBERON:0000064!3.61e-08!219;UBERON:0000947!1.24e-07!21;UBERON:0010191!1.24e-07!21;UBERON:0000490!1.96e-07!138;UBERON:0003076!7.35e-07!15;UBERON:0003057!7.35e-07!15
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}}
}}

Revision as of 12:53, 5 September 2012


Full id: C4175_putamen_pons_heart_occipital_parietal_medial_paracentral



Phase1 CAGE Peaks

Hg19::chr2:207308220..207308267,+p1@ADAM23
Hg19::chr2:207308275..207308295,+p2@ADAM23
Hg19::chr2:207308554..207308568,+p5@ADAM23


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
regional part of nervous system6.88e-3394
nervous system6.88e-3394
central nervous system3.36e-3182
cell layer2.76e-29312
epithelium4.03e-29309
neural plate8.94e-2986
presumptive neural plate8.94e-2986
neurectoderm1.07e-2790
neural tube1.74e-2757
neural rod1.74e-2757
future spinal cord1.74e-2757
neural keel1.74e-2757
brain5.91e-2669
future brain5.91e-2669
regional part of brain1.09e-2559
tube3.33e-24194
regional part of forebrain4.13e-2241
forebrain4.13e-2241
future forebrain4.13e-2241
pre-chordal neural plate5.08e-2261
ectoderm-derived structure5.74e-22169
anterior neural tube7.20e-2242
ectoderm1.33e-21173
presumptive ectoderm1.33e-21173
anatomical conduit2.43e-21241
gray matter1.70e-1934
brain grey matter1.70e-1934
telencephalon2.06e-1934
head4.23e-19123
cerebral hemisphere5.41e-1932
anterior region of body8.04e-19129
craniocervical region8.04e-19129
regional part of telencephalon1.00e-1833
anatomical cluster2.08e-18286
organism subdivision2.80e-17365
vasculature1.40e-1679
vascular system1.40e-1679
adult organism1.73e-16115
blood vessel4.98e-1660
epithelial tube open at both ends4.98e-1660
blood vasculature4.98e-1660
vascular cord4.98e-1660
circulatory system2.48e-15113
vessel3.15e-1569
splanchnic layer of lateral plate mesoderm5.52e-1584
cerebral cortex6.61e-1525
pallium6.61e-1525
regional part of cerebral cortex7.27e-1522
cardiovascular system5.48e-14110
neocortex1.07e-1320
multi-tissue structure2.44e-13347
artery2.89e-1342
arterial blood vessel2.89e-1342
arterial system2.89e-1342
skeletal muscle tissue2.90e-1261
striated muscle tissue2.90e-1261
myotome2.90e-1261
muscle tissue1.19e-1163
musculature1.19e-1163
musculature of body1.19e-1163
multi-cellular organism1.90e-11659
dermomyotome4.88e-1170
anatomical group3.78e-10626
embryo4.11e-10612
somite4.38e-1083
paraxial mesoderm4.38e-1083
presomitic mesoderm4.38e-1083
presumptive segmental plate4.38e-1083
trunk paraxial mesoderm4.38e-1083
presumptive paraxial mesoderm4.38e-1083
anatomical system4.79e-10625
systemic artery5.96e-1033
systemic arterial system5.96e-1033
embryonic structure1.69e-08605
developing anatomical structure1.69e-08605
multilaminar epithelium2.40e-0882
germ layer2.90e-08604
embryonic tissue2.90e-08604
presumptive structure2.90e-08604
epiblast (generic)2.90e-08604
organ part3.61e-08219
aorta1.24e-0721
aortic system1.24e-0721
unilaminar epithelium1.96e-07138
posterior neural tube7.35e-0715


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
EGR1#195834.988179094810140.008056488137383440.0321370240844928



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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