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|id=CL:0000875
|id=CL:0000875
|name=non-classical monocyte
|name=non-classical monocyte
|namespace=cell
|namespace=efo
|def="Subset of monocytes characterized by low expression of CCR2, low responsiveness to monocyte chemoattractant CCL2/MCP1, low phagocytic activity, but increased co-stimulatory activity. May also play a role in tissue repair." [GO_REF:0000031, PMID:16322748, PMID:18303997, PMID:20628149, PMID:20870168]
|def="Subset of monocytes characterized by low expression of CCR2, low responsiveness to monocyte chemoattractant CCL2/MCP1, low phagocytic activity, but increased co-stimulatory activity. May also play a role in tissue repair." [GO_REF:0000031, PMID:16322748, PMID:18303997, PMID:20628149, PMID:20870168]
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|located_in=
|located_in=
|part_of=
|part_of=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.obo.owl
|is_obsolete=
|preceded_by=
}}
}}

Revision as of 17:39, 15 June 2012

Name:non-classical monocyte
Namespace:efo
Definition:"Subset of monocytes characterized by low expression of CCR2, low responsiveness to monocyte chemoattractant CCL2/MCP1, low phagocytic activity, but increased co-stimulatory activity. May also play a role in tissue repair." [GO_REF:0000031, PMID:16322748, PMID:18303997, PMID:20628149, PMID:20870168]
Synonyms: "patrolling monocyte" EXACT []
"resident monocyte" EXACT []
Comments:Markers: CCR2-CX3CCR1+ (human, mouse, rat); human: CD16+, CCR5+, CD32/FcgRII-high, MHCII+, CD86+; mouse: CD62L-Ly6C-.


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:CL:0000576(monocyte)



Children


is a:CL:0002396 (CD14-low, CD16-positive monocyte)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.

Human (Homo sapiens)

Mouse (Mus musculus)


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000875 (non-classical monocyte), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
3.27e-147FFCP PHASE2:Hg19::chr8:144480343..144480350,-#_10f4afad32065d713da8df9482fc9195p@chr8:144480343..144480350, -
3.27e-147FFCP PHASE1:Hg19::chr8:144480343..144480350,-#_10f4afad32065d713da8df9482fc9195p@chr8:144480343..144480350, -
1.47e-146FFCP PHASE1:Hg19::chr15:22550731..22550738,+#_a7f5665d1ef30583f4388abe2936ff7dp@chr15:22550731..22550738, +
1.47e-146FFCP PHASE2:Hg19::chr15:22550731..22550738,+#_a7f5665d1ef30583f4388abe2936ff7dp@chr15:22550731..22550738, +
2.33e-118FFCP PHASE1:Hg19::chr15:22538560..22538601,-#_26a9739a0c15b051bf11b7797845a2aap@chr15:22538560..22538601, -
2.33e-118FFCP PHASE1:Hg19::chr10:43609342..43609351,+#_26a9739a0c15b051bf11b7797845a2aap@chr10:43609342..43609351, +
2.33e-118FFCP PHASE2:Hg19::chr10:43609342..43609351,+#_26a9739a0c15b051bf11b7797845a2aap@chr10:43609342..43609351, +
2.33e-118FFCP PHASE2:Hg19::chr15:22538560..22538601,-#_26a9739a0c15b051bf11b7797845a2aap@chr15:22538560..22538601, -
7.78e-118FFCP PHASE2:Hg19::chr15:22550782..22550787,+#_37f94897377b168045cb3ce25502f215p@chr15:22550782..22550787, +
7.78e-118FFCP PHASE1:Hg19::chr15:22550782..22550787,+#_37f94897377b168045cb3ce25502f215p@chr15:22550782..22550787, +
1.16e-117FFCP PHASE2:Hg19::chr7:101923267..101923278,+#_ba60fb76f89154a5e39d04bc84707d1fp@chr7:101923267..101923278, +
1.16e-117FFCP PHASE1:Hg19::chr7:101923267..101923278,+#_ba60fb76f89154a5e39d04bc84707d1fp@chr7:101923267..101923278, +
4.06e-99FFCP PHASE1:Hg19::chr10:115070193..115070207,-#_4fcc963540346e3c4a0b6b2eb4cf23f4p@chr10:115070193..115070207, -
4.06e-99FFCP PHASE2:Hg19::chr10:115070193..115070207,-#_4fcc963540346e3c4a0b6b2eb4cf23f4p@chr10:115070193..115070207, -
4.06e-99FFCP PHASE2:Hg19::chr1:161519682..161519691,-#_4fcc963540346e3c4a0b6b2eb4cf23f4p7@FCGR3A
4.06e-99FFCP PHASE1:Hg19::chr1:161519682..161519691,-#_4fcc963540346e3c4a0b6b2eb4cf23f4p7@FCGR3A
2.17e-98FFCP PHASE1:Hg19::chr15:22550810..22550816,+#_7ec7885e1be75087daf1c0a1eacad79ep@chr15:22550810..22550816, +
2.17e-98FFCP PHASE2:Hg19::chr15:22550810..22550816,+#_7ec7885e1be75087daf1c0a1eacad79ep@chr15:22550810..22550816, +
3.03e-98FFCP PHASE1:Hg19::chr17:40351201..40351230,+#_bf368cb0794b10a82988bc71491e27fdp@chr17:40351201..40351230, +
3.03e-98FFCP PHASE1:Hg19::chr10:134234820..134234825,+#_bf368cb0794b10a82988bc71491e27fdp@chr10:134234820..134234825, +
3.03e-98FFCP PHASE2:Hg19::chr10:134234820..134234825,+#_bf368cb0794b10a82988bc71491e27fdp@chr10:134234820..134234825, +
3.03e-98FFCP PHASE2:Hg19::chr17:40351201..40351230,+#_bf368cb0794b10a82988bc71491e27fdp@chr17:40351201..40351230, +
2.28e-85FFCP PHASE2:Hg19::chr7:20581331..20581339,-#_6640db1e0f300a83e7e2460829f91fd7p@chr7:20581331..20581339, -
2.28e-85FFCP PHASE2:Hg19::chr12:29727591..29727616,-#_6640db1e0f300a83e7e2460829f91fd7p@chr12:29727591..29727616, -
2.28e-85FFCP PHASE1:Hg19::chr7:20581331..20581339,-#_6640db1e0f300a83e7e2460829f91fd7p@chr7:20581331..20581339, -
2.28e-85FFCP PHASE2:Hg19::chr7:20581377..20581387,-#_6640db1e0f300a83e7e2460829f91fd7p@chr7:20581377..20581387, -
2.28e-85FFCP PHASE1:Hg19::chr15:22550722..22550726,+#_6640db1e0f300a83e7e2460829f91fd7p@chr15:22550722..22550726, +
2.28e-85FFCP PHASE2:Hg19::chr7:155055063..155055078,+#_6640db1e0f300a83e7e2460829f91fd7p@chr7:155055063..155055078, +
2.28e-85FFCP PHASE1:Hg19::chr7:20581377..20581387,-#_6640db1e0f300a83e7e2460829f91fd7p@chr7:20581377..20581387, -
2.28e-85FFCP PHASE2:Hg19::chr15:22550722..22550726,+#_6640db1e0f300a83e7e2460829f91fd7p@chr15:22550722..22550726, +
2.28e-85FFCP PHASE1:Hg19::chr7:155055063..155055078,+#_6640db1e0f300a83e7e2460829f91fd7p@chr7:155055063..155055078, +
2.28e-85FFCP PHASE2:Hg19::chr17:47287786..47287800,-#_6640db1e0f300a83e7e2460829f91fd7p@chr17:47287786..47287800, -
2.28e-85FFCP PHASE1:Hg19::chr12:29727591..29727616,-#_6640db1e0f300a83e7e2460829f91fd7p@chr12:29727591..29727616, -
2.28e-85FFCP PHASE1:Hg19::chr17:47287786..47287800,-#_6640db1e0f300a83e7e2460829f91fd7p@chr17:47287786..47287800, -
3.04e-85FFCP PHASE1:Hg19::chr16:1538765..1538796,-#_f978a64d323c9a23f82e1d9c2c5b2b6fp1@PTX4
3.04e-85FFCP PHASE2:Hg19::chr16:1538765..1538796,-#_f978a64d323c9a23f82e1d9c2c5b2b6fp1@PTX4
4.06e-85FFCP PHASE1:Hg19::chr15:75080883..75080890,+#_c28fa51f3c91aaab957447e4efe7d391p14@CSK
4.06e-85FFCP PHASE2:Hg19::chr15:75080883..75080890,+#_c28fa51f3c91aaab957447e4efe7d391p14@CSK
7.21e-85FFCP PHASE2:Hg19::chr4:2794535..2794549,-#_c9651190742648153934e0ba06587ad6p@chr4:2794535..2794549, -
7.21e-85FFCP PHASE1:Hg19::chr4:2794535..2794549,-#_c9651190742648153934e0ba06587ad6p@chr4:2794535..2794549, -
6.07e-75FFCP PHASE2:Hg19::chr9:137267629..137267639,-#_dcc5d3b12b021e189958c2ed7bc7c523p@chr9:137267629..137267639, -
6.07e-75FFCP PHASE1:Hg19::chr9:137267629..137267639,-#_dcc5d3b12b021e189958c2ed7bc7c523p@chr9:137267629..137267639, -
7.81e-75FFCP PHASE2:Hg19::chr6:31584663..31584673,-#_8ef1864bde45f5c25ed63060cab37ed4p@chr6:31584663..31584673, -
7.81e-75FFCP PHASE1:Hg19::chr6:31584663..31584673,-#_8ef1864bde45f5c25ed63060cab37ed4p@chr6:31584663..31584673, -
5.01e-67FFCP PHASE2:Hg19::chr6:144952186..144952227,+#_1db0e821783627536ffd5dea1b4a2c65p@chr6:144952186..144952227, +
5.01e-67FFCP PHASE1:Hg19::chr6:144952186..144952227,+#_1db0e821783627536ffd5dea1b4a2c65p@chr6:144952186..144952227, +
5.01e-67FFCP PHASE2:Hg19::chr3:101597149..101597179,+#_1db0e821783627536ffd5dea1b4a2c65p@chr3:101597149..101597179, +
5.01e-67FFCP PHASE1:Hg19::chr16:4563100..4563144,-#_1db0e821783627536ffd5dea1b4a2c65p12@C16orf5
5.01e-67FFCP PHASE2:Hg19::chr20:825297..825306,+#_1db0e821783627536ffd5dea1b4a2c65p7@FAM110A
5.01e-67FFCP PHASE1:Hg19::chr10:114594528..114594539,-#_1db0e821783627536ffd5dea1b4a2c65p@chr10:114594528..114594539, -
5.01e-67FFCP PHASE1:Hg19::chr3:101597149..101597179,+#_1db0e821783627536ffd5dea1b4a2c65p@chr3:101597149..101597179, +
5.01e-67FFCP PHASE2:Hg19::chr16:4563100..4563144,-#_1db0e821783627536ffd5dea1b4a2c65p12@C16orf5
5.01e-67FFCP PHASE1:Hg19::chr20:825297..825306,+#_1db0e821783627536ffd5dea1b4a2c65p7@FAM110A
5.01e-67FFCP PHASE2:Hg19::chr10:114594528..114594539,-#_1db0e821783627536ffd5dea1b4a2c65p@chr10:114594528..114594539, -
5.01e-67FFCP PHASE2:Hg19::chr2:29337114..29337117,+#_1db0e821783627536ffd5dea1b4a2c65p21@CLIP4
5.01e-67FFCP PHASE1:Hg19::chr2:29337114..29337117,+#_1db0e821783627536ffd5dea1b4a2c65p21@CLIP4
6.27e-67FFCP PHASE2:Hg19::chr2:241906877..241906887,-#_1eb841de3a8762c1013c5bfa8146d2bfp3@LOC200772
6.27e-67FFCP PHASE1:Hg19::chr2:241906877..241906887,-#_1eb841de3a8762c1013c5bfa8146d2bfp3@LOC200772
6.27e-67FFCP PHASE2:Hg19::chr11:67415202..67415246,-#_1eb841de3a8762c1013c5bfa8146d2bfp5@ACY3
6.27e-67FFCP PHASE1:Hg19::chr11:67415202..67415246,-#_1eb841de3a8762c1013c5bfa8146d2bfp5@ACY3
6.27e-67FFCP PHASE1:Hg19::chr10:115080077..115080087,-#_1eb841de3a8762c1013c5bfa8146d2bfp@chr10:115080077..115080087, -
6.27e-67FFCP PHASE2:Hg19::chr10:115080077..115080087,-#_1eb841de3a8762c1013c5bfa8146d2bfp@chr10:115080077..115080087, -
9.82e-67FFCP PHASE1:Hg19::chr2:2685878..2685892,+#_f69715357c0bbacfe5d9e3eac03e6789p@chr2:2685878..2685892, +
9.82e-67FFCP PHASE2:Hg19::chr19:50285177..50285181,+#_f69715357c0bbacfe5d9e3eac03e6789p@chr19:50285177..50285181, +
9.82e-67FFCP PHASE1:Hg19::chr19:50285177..50285181,+#_f69715357c0bbacfe5d9e3eac03e6789p@chr19:50285177..50285181, +
9.82e-67FFCP PHASE2:Hg19::chr20:827656..827661,-#_f69715357c0bbacfe5d9e3eac03e6789p@chr20:827656..827661, -
9.82e-67FFCP PHASE1:Hg19::chr20:827656..827661,-#_f69715357c0bbacfe5d9e3eac03e6789p@chr20:827656..827661, -
9.82e-67FFCP PHASE2:Hg19::chr2:2685878..2685892,+#_f69715357c0bbacfe5d9e3eac03e6789p@chr2:2685878..2685892, +
2.39e-66FFCP PHASE2:Hg19::chr5:172232848..172232850,-#_7520eb33c065d180fc24c375e67306b0p@chr5:172232848..172232850, -
2.39e-66FFCP PHASE1:Hg19::chr5:172232848..172232850,-#_7520eb33c065d180fc24c375e67306b0p@chr5:172232848..172232850, -
3.76e-66FFCP PHASE2:Hg19::chr17:4689735..4689745,-#_8398c5f2fe64ac896388d60705fa6e08p2@VMO1
3.76e-66FFCP PHASE2:Hg19::chr8:56800914..56800925,+#_8398c5f2fe64ac896388d60705fa6e08p@chr8:56800914..56800925, +
3.76e-66FFCP PHASE1:Hg19::chr17:4689735..4689745,-#_8398c5f2fe64ac896388d60705fa6e08p2@VMO1
3.76e-66FFCP PHASE1:Hg19::chr8:56800914..56800925,+#_8398c5f2fe64ac896388d60705fa6e08p@chr8:56800914..56800925, +
3.76e-66FFCP PHASE2:Hg19::chr2:121011117..121011127,+#_8398c5f2fe64ac896388d60705fa6e08p16@RALB
3.76e-66FFCP PHASE1:Hg19::chr2:121011117..121011127,+#_8398c5f2fe64ac896388d60705fa6e08p16@RALB
4.68e-66FFCP PHASE2:Hg19::chr2:241906961..241906992,+#_3a871d825844c08b452993ce16f50e5cp@chr2:241906961..241906992, +
4.68e-66FFCP PHASE1:Hg19::chr2:241906961..241906992,+#_3a871d825844c08b452993ce16f50e5cp@chr2:241906961..241906992, +
1.33e-60FFCP PHASE1:Hg19::chr14:23282256..23282282,-#_f35ffc3acfaa23f76294038ceaadad95p17@SLC7A7
1.33e-60FFCP PHASE2:Hg19::chr14:23282256..23282282,-#_f35ffc3acfaa23f76294038ceaadad95p17@SLC7A7
1.33e-60FFCP PHASE1:Hg19::chr16:1538881..1538887,+#_f35ffc3acfaa23f76294038ceaadad95p@chr16:1538881..1538887, +
1.33e-60FFCP PHASE2:Hg19::chr16:1538881..1538887,+#_f35ffc3acfaa23f76294038ceaadad95p@chr16:1538881..1538887, +
1.62e-60FFCP PHASE2:Hg19::chr5:56136714..56136717,+#_cd1e729eef9e835ef4b24b98da91ecb6p@chr5:56136714..56136717, +
1.62e-60FFCP PHASE1:Hg19::chr5:56136714..56136717,+#_cd1e729eef9e835ef4b24b98da91ecb6p@chr5:56136714..56136717, +
2.43e-60FFCP PHASE2:Hg19::chr3:50654306..50654308,-#_0cf5a92bd72b99a95e5e203dc21cb17dp@chr3:50654306..50654308, -
2.43e-60FFCP PHASE1:Hg19::chr3:50654306..50654308,-#_0cf5a92bd72b99a95e5e203dc21cb17dp@chr3:50654306..50654308, -
2.43e-60FFCP PHASE2:Hg19::chr3:50658125..50658131,+#_0cf5a92bd72b99a95e5e203dc21cb17dp@chr3:50658125..50658131, +
2.43e-60FFCP PHASE1:Hg19::chr3:50658125..50658131,+#_0cf5a92bd72b99a95e5e203dc21cb17dp@chr3:50658125..50658131, +
2.43e-60FFCP PHASE2:Hg19::chr6:144980558..144980569,+#_0cf5a92bd72b99a95e5e203dc21cb17dp30@UTRN
2.43e-60FFCP PHASE1:Hg19::chr6:144980558..144980569,+#_0cf5a92bd72b99a95e5e203dc21cb17dp30@UTRN
1.22e-59FFCP PHASE2:Hg19::chr7:2797828..2797848,-#_3324e9bfaa3adcbd86de9383df587de1p@chr7:2797828..2797848, -
1.22e-59FFCP PHASE1:Hg19::chr7:2797828..2797848,-#_3324e9bfaa3adcbd86de9383df587de1p@chr7:2797828..2797848, -
2.4e-55FFCP PHASE2:Hg19::chr19:14546214..14546245,+#_e68ab7b85940999b20e3448e4afbaee9p@chr19:14546214..14546245, +
2.4e-55FFCP PHASE1:Hg19::chr19:14546214..14546245,+#_e68ab7b85940999b20e3448e4afbaee9p@chr19:14546214..14546245, +
2.4e-55FFCP PHASE2:Hg19::chr8:142384243..142384251,+#_e68ab7b85940999b20e3448e4afbaee9p@chr8:142384243..142384251, +
2.4e-55FFCP PHASE1:Hg19::chr8:142384243..142384251,+#_e68ab7b85940999b20e3448e4afbaee9p@chr8:142384243..142384251, +
2.4e-55FFCP PHASE2:Hg19::chr17:531709..531723,-#_e68ab7b85940999b20e3448e4afbaee9p@chr17:531709..531723, -
2.4e-55FFCP PHASE1:Hg19::chr17:531709..531723,-#_e68ab7b85940999b20e3448e4afbaee9p@chr17:531709..531723, -
2.88e-55FFCP PHASE2:Hg19::chr2:86225195..86225216,-#_c5344efe978e028a1d2526995b337f96p@chr2:86225195..86225216, -
2.88e-55FFCP PHASE1:Hg19::chr2:86225195..86225216,-#_c5344efe978e028a1d2526995b337f96p@chr2:86225195..86225216, -

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