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Revision as of 17:17, 15 June 2012

Name:otic placode
Definition:"A cranial placode which, once specified, invaginates to form an otic cup, which eventually separates from the surface ectoderm to form the otic vesicle or otocyst, a rounded structure without appar- ent polarity. As the otic placode invaginates into a cup neuroblasts delaminate from the anterior ventral aspect of the otic epithelium to give rise to neurons of the vestibulocochlear (statoacoustic) ganglion of cranial nerve VIII" [NBK:NBK53175]
Xrefs:
links:

AAO:0011079
EFO:0003429
EHDAA:506
EHDAA2:0001339
EMAPA:16195
ncithesaurus:Otic_Placodes
TAO:0000138
VHOG:0000235
XAO:0000223

ZFA:0000138
Synonyms: "auditory placode" RELATED []
"ear placode" RELATED []
"ear/otic placode" RELATED []
Comments:With the exception of the pigment cells of the stria vascularis and the secretory epithelium of the cochlea, which are of neural crest origin, all compo- nents of the inner ear derive from the otic placode. In most species the thickening of the ectoderm into a placode occurs in a region adjacent to rhombomere 5 (reviewed in Ohyama et al., 2007), while in amphibians the otic placode is centered onto rhombomere 4 (Ruiz i Altaba and Jessell, 1991).[NBK53175]
Alt_id: UBERON:XAO_0000223-ZFA_0000138
Subset: uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0003067(dorsolateral placode),UBERON:0005085(ectodermal placode)
part_of:UBERON:0001690(ear)



Children

develops from:UBERON:0009123 (otic cup)
part of:UBERON:0003249 (epithelium of otic placode)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology



Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0003069 (otic placode), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
1.87e-86FFCP PHASE1:Mm9::chr6:113251614..113251623,+#_79a6708211b885bd34d9bea04e5ffea8p@chr6:113251614..113251623, +
1.87e-86FFCP PHASE2:Mm9::chr3:100724698..100724706,+#_79a6708211b885bd34d9bea04e5ffea8p@chr3:100724698..100724706, +
1.87e-86FFCP PHASE2:Mm9::chr6:30619378..30619412,-#_79a6708211b885bd34d9bea04e5ffea8p11@Tsga14
1.87e-86FFCP PHASE2:Mm9::chr19:10536797..10536802,-#_79a6708211b885bd34d9bea04e5ffea8p@chr19:10536797..10536802, -
1.87e-86FFCP PHASE2:Mm9::chr9:56208792..56208814,-#_79a6708211b885bd34d9bea04e5ffea8p@chr9:56208792..56208814, -
1.87e-86FFCP PHASE2:Mm9::chr9:42207887..42207960,-#_79a6708211b885bd34d9bea04e5ffea8p1@Tecta
1.87e-86FFCP PHASE1:Mm9::chr10:107156949..107156956,-#_79a6708211b885bd34d9bea04e5ffea8p3@Ptprq
1.87e-86FFCP PHASE2:Mm9::chr1:172843813..172843834,-#_79a6708211b885bd34d9bea04e5ffea8p@chr1:172843813..172843834, -
1.87e-86FFCP PHASE2:Mm9::chr4:130461150..130461185,+#_79a6708211b885bd34d9bea04e5ffea8p@chr4:130461150..130461185, +
1.87e-86FFCP PHASE2:Mm9::chr3:35012425..35012439,+#_79a6708211b885bd34d9bea04e5ffea8p@chr3:35012425..35012439, +
1.87e-86FFCP PHASE2:Mm9::chr4:115556989..115556997,+#_79a6708211b885bd34d9bea04e5ffea8p1@Kncn
1.87e-86FFCP PHASE2:Mm9::chr17:13983160..13983167,+#_79a6708211b885bd34d9bea04e5ffea8p@chr17:13983160..13983167, +
1.87e-86FFCP PHASE1:Mm9::chr9:42207887..42207960,-#_79a6708211b885bd34d9bea04e5ffea8p1@Tecta
1.87e-86FFCP PHASE2:Mm9::chr9:42206745..42206774,-#_79a6708211b885bd34d9bea04e5ffea8p@chr9:42206745..42206774, -
1.87e-86FFCP PHASE2:Mm9::chr19:55255206..55255223,+#_79a6708211b885bd34d9bea04e5ffea8p1@Tectb
1.87e-86FFCP PHASE2:Mm9::chr3:106986057..106986062,+#_79a6708211b885bd34d9bea04e5ffea8p1@Kcna10
1.87e-86FFCP PHASE1:Mm9::chr3:35012397..35012405,+#_79a6708211b885bd34d9bea04e5ffea8p@chr3:35012397..35012405, +
1.87e-86FFCP PHASE2:Mm9::chr11:102123535..102123544,+#_79a6708211b885bd34d9bea04e5ffea8p5@BC030867
1.87e-86FFCP PHASE1:Mm9::chr1:172843885..172843890,-#_79a6708211b885bd34d9bea04e5ffea8p@chr1:172843885..172843890, -
1.87e-86FFCP PHASE1:Mm9::chr2:67011921..67011934,+#_79a6708211b885bd34d9bea04e5ffea8p2@Gm1322
1.87e-86FFCP PHASE2:Mm9::chr1:93218694..93218705,+#_79a6708211b885bd34d9bea04e5ffea8p1@Espnl
1.87e-86FFCP PHASE2:Mm9::chr18:42158627..42158630,-#_79a6708211b885bd34d9bea04e5ffea8p@chr18:42158627..42158630, -
1.87e-86FFCP PHASE1:Mm9::chr9:66860888..66860899,+#_79a6708211b885bd34d9bea04e5ffea8p@chr9:66860888..66860899, +
1.87e-86FFCP PHASE1:Mm9::chr13:43699188..43699216,+#_79a6708211b885bd34d9bea04e5ffea8p@chr13:43699188..43699216, +
1.87e-86FFCP PHASE2:Mm9::chr13:78257491..78257498,+#_79a6708211b885bd34d9bea04e5ffea8p@chr13:78257491..78257498, +
1.87e-86FFCP PHASE1:Mm9::chr7:109052297..109052300,-#_79a6708211b885bd34d9bea04e5ffea8p2@Tomt
1.87e-86FFCP PHASE2:Mm9::chr2:128881546..128881553,-#_79a6708211b885bd34d9bea04e5ffea8p@chr2:128881546..128881553, -
1.87e-86FFCP PHASE1:Mm9::chr5:30710403..30710406,-#_79a6708211b885bd34d9bea04e5ffea8p10@Otof
1.87e-86FFCP PHASE2:Mm9::chr4:151505798..151505818,-#_79a6708211b885bd34d9bea04e5ffea8p21@Espn
1.87e-86FFCP PHASE1:Mm9::chr9:42206745..42206774,-#_79a6708211b885bd34d9bea04e5ffea8p@chr9:42206745..42206774, -
1.87e-86FFCP PHASE2:Mm9::chr12:13508046..13508055,+#_79a6708211b885bd34d9bea04e5ffea8p@chr12:13508046..13508055, +
1.87e-86FFCP PHASE2:Mm9::chr5:150945209..150945220,+#_79a6708211b885bd34d9bea04e5ffea8p@chr5:150945209..150945220, +
1.87e-86FFCP PHASE1:Mm9::chr10:80806020..80806031,-#_79a6708211b885bd34d9bea04e5ffea8p3@Gipc3
1.87e-86FFCP PHASE1:Mm9::chr15:58480061..58480066,+#_79a6708211b885bd34d9bea04e5ffea8p5@Fer1l6
1.87e-86FFCP PHASE2:Mm9::chr3:154693281..154693317,-#_79a6708211b885bd34d9bea04e5ffea8p@chr3:154693281..154693317, -
1.87e-86FFCP PHASE2:Mm9::chr9:42208142..42208157,-#_79a6708211b885bd34d9bea04e5ffea8p10@Tecta
1.87e-86FFCP PHASE1:Mm9::chr2:128881546..128881553,-#_79a6708211b885bd34d9bea04e5ffea8p@chr2:128881546..128881553, -
1.87e-86FFCP PHASE1:Mm9::chrX:154140800..154140810,+#_79a6708211b885bd34d9bea04e5ffea8p@chrX:154140800..154140810, +
1.87e-86FFCP PHASE1:Mm9::chr3:81012915..81012923,+#_79a6708211b885bd34d9bea04e5ffea8p@chr3:81012915..81012923, +
1.87e-86FFCP PHASE1:Mm9::chr10:107349392..107349413,-#_79a6708211b885bd34d9bea04e5ffea8p2@Otogl
1.87e-86FFCP PHASE2:Mm9::chr2:152453066..152453075,-#_79a6708211b885bd34d9bea04e5ffea8p@chr2:152453066..152453075, -
1.87e-86FFCP PHASE1:Mm9::chr17:13983102..13983126,+#_79a6708211b885bd34d9bea04e5ffea8p@chr17:13983102..13983126, +
1.87e-86FFCP PHASE2:Mm9::chr17:31335903..31335921,-#_79a6708211b885bd34d9bea04e5ffea8p2@Tmprss3
1.87e-86FFCP PHASE2:Mm9::chr14:47293496..47293510,-#_79a6708211b885bd34d9bea04e5ffea8p@chr14:47293496..47293510, -
1.87e-86FFCP PHASE1:Mm9::chr9:42208142..42208157,-#_79a6708211b885bd34d9bea04e5ffea8p10@Tecta
1.87e-86FFCP PHASE1:Mm9::chr15:103146966..103146971,-#_79a6708211b885bd34d9bea04e5ffea8p@chr15:103146966..103146971, -
1.87e-86FFCP PHASE2:Mm9::chr6:86746562..86746579,-#_79a6708211b885bd34d9bea04e5ffea8p@chr6:86746562..86746579, -
1.87e-86FFCP PHASE2:Mm9::chr15:58480061..58480066,+#_79a6708211b885bd34d9bea04e5ffea8p5@Fer1l6
1.87e-86FFCP PHASE2:Mm9::chr9:42207777..42207789,-#_79a6708211b885bd34d9bea04e5ffea8p7@Tecta
1.87e-86FFCP PHASE1:Mm9::chr19:55256373..55256384,+#_79a6708211b885bd34d9bea04e5ffea8p@chr19:55256373..55256384, +
1.87e-86FFCP PHASE1:Mm9::chr13:78322370..78322376,-#_79a6708211b885bd34d9bea04e5ffea8p4@uc007rhb.1
1.87e-86FFCP PHASE1:Mm9::chr11:102123554..102123566,+#_79a6708211b885bd34d9bea04e5ffea8p4@BC030867
1.87e-86FFCP PHASE1:Mm9::chr3:58626291..58626298,-#_79a6708211b885bd34d9bea04e5ffea8p@chr3:58626291..58626298, -
1.87e-86FFCP PHASE1:Mm9::chr7:133957514..133957529,+#_79a6708211b885bd34d9bea04e5ffea8p@chr7:133957514..133957529, +
1.87e-86FFCP PHASE1:Mm9::chr1:182528371..182528385,+#_79a6708211b885bd34d9bea04e5ffea8p@chr1:182528371..182528385, +
1.87e-86FFCP PHASE1:Mm9::chr14:31283085..31283097,-#_79a6708211b885bd34d9bea04e5ffea8p@chr14:31283085..31283097, -
1.87e-86FFCP PHASE1:Mm9::chr11:75421384..75421397,+#_79a6708211b885bd34d9bea04e5ffea8p@chr11:75421384..75421397, +
1.87e-86FFCP PHASE2:Mm9::chr4:63079735..63079745,-#_79a6708211b885bd34d9bea04e5ffea8p@chr4:63079735..63079745, -
1.87e-86FFCP PHASE2:Mm9::chr5:147854240..147854249,-#_79a6708211b885bd34d9bea04e5ffea8p@chr5:147854240..147854249, -
1.87e-86FFCP PHASE2:Mm9::chr10:107349430..107349440,-#_79a6708211b885bd34d9bea04e5ffea8p3@Otogl
1.87e-86FFCP PHASE1:Mm9::chr19:10536767..10536777,-#_79a6708211b885bd34d9bea04e5ffea8p@chr19:10536767..10536777, -
1.87e-86FFCP PHASE2:Mm9::chr8:13414266..13414279,+#_79a6708211b885bd34d9bea04e5ffea8p@chr8:13414266..13414279, +
1.87e-86FFCP PHASE2:Mm9::chr2:53464168..53464175,+#_79a6708211b885bd34d9bea04e5ffea8p@chr2:53464168..53464175, +
1.87e-86FFCP PHASE2:Mm9::chr5:72652660..72652667,+#_79a6708211b885bd34d9bea04e5ffea8p@chr5:72652660..72652667, +
1.87e-86FFCP PHASE2:Mm9::chr11:89702580..89702593,-#_79a6708211b885bd34d9bea04e5ffea8p@chr11:89702580..89702593, -
1.87e-86FFCP PHASE1:Mm9::chr9:42207777..42207789,-#_79a6708211b885bd34d9bea04e5ffea8p7@Tecta
1.87e-86FFCP PHASE1:Mm9::chr1:93235253..93235264,+#_79a6708211b885bd34d9bea04e5ffea8p@chr1:93235253..93235264, +
1.87e-86FFCP PHASE2:Mm9::chr2:136942131..136942142,-#_79a6708211b885bd34d9bea04e5ffea8p6@Jag1
1.87e-86FFCP PHASE1:Mm9::chr15:89215306..89215315,+#_79a6708211b885bd34d9bea04e5ffea8p@chr15:89215306..89215315, +
1.87e-86FFCP PHASE1:Mm9::chr13:48087761..48087775,-#_79a6708211b885bd34d9bea04e5ffea8p@chr13:48087761..48087775, -
1.87e-86FFCP PHASE2:Mm9::chr11:114603036..114603048,+#_79a6708211b885bd34d9bea04e5ffea8p@chr11:114603036..114603048, +
1.87e-86FFCP PHASE2:Mm9::chr16:93971325..93971337,-#_79a6708211b885bd34d9bea04e5ffea8p@chr16:93971325..93971337, -
1.87e-86FFCP PHASE1:Mm9::chr11:4689776..4689785,-#_79a6708211b885bd34d9bea04e5ffea8p@chr11:4689776..4689785, -
1.87e-86FFCP PHASE2:Mm9::chr1:154246932..154246939,+#_79a6708211b885bd34d9bea04e5ffea8p7@Glt25d2
1.87e-86FFCP PHASE1:Mm9::chr5:3909310..3909321,+#_79a6708211b885bd34d9bea04e5ffea8p@chr5:3909310..3909321, +
1.87e-86FFCP PHASE1:Mm9::chr4:115556972..115556979,+#_79a6708211b885bd34d9bea04e5ffea8p3@Kncn
1.87e-86FFCP PHASE1:Mm9::chr16:93971325..93971337,-#_79a6708211b885bd34d9bea04e5ffea8p@chr16:93971325..93971337, -
1.87e-86FFCP PHASE2:Mm9::chr8:13435173..13435186,+#_79a6708211b885bd34d9bea04e5ffea8p6@Fam70b
1.87e-86FFCP PHASE2:Mm9::chr2:121206667..121206674,-#_79a6708211b885bd34d9bea04e5ffea8p2@Strc
1.87e-86FFCP PHASE1:Mm9::chr17:31335869..31335899,-#_79a6708211b885bd34d9bea04e5ffea8p1@Tmprss3
1.87e-86FFCP PHASE2:Mm9::chr10:81091447..81091464,+#_79a6708211b885bd34d9bea04e5ffea8p9@Ankrd24
1.87e-86FFCP PHASE2:Mm9::chr1:78523144..78523177,+#_79a6708211b885bd34d9bea04e5ffea8p@chr1:78523144..78523177, +
1.87e-86FFCP PHASE2:Mm9::chr7:53496326..53496340,+#_79a6708211b885bd34d9bea04e5ffea8p1@Otog
1.87e-86FFCP PHASE2:Mm9::chr5:3909310..3909321,+#_79a6708211b885bd34d9bea04e5ffea8p@chr5:3909310..3909321, +
1.87e-86FFCP PHASE2:Mm9::chr14:31283072..31283081,-#_79a6708211b885bd34d9bea04e5ffea8p@chr14:31283072..31283081, -
1.87e-86FFCP PHASE2:Mm9::chr11:75421384..75421397,+#_79a6708211b885bd34d9bea04e5ffea8p@chr11:75421384..75421397, +
1.87e-86FFCP PHASE1:Mm9::chr10:108316802..108316807,-#_79a6708211b885bd34d9bea04e5ffea8p@chr10:108316802..108316807, -
1.87e-86FFCP PHASE1:Mm9::chr14:63099970..63099980,-#_79a6708211b885bd34d9bea04e5ffea8p@chr14:63099970..63099980, -
1.87e-86FFCP PHASE2:Mm9::chr19:4140290..4140321,+#_79a6708211b885bd34d9bea04e5ffea8p2@Gpr152
1.87e-86FFCP PHASE1:Mm9::chr4:133802857..133802884,+#_79a6708211b885bd34d9bea04e5ffea8p@chr4:133802857..133802884, +
1.87e-86FFCP PHASE2:Mm9::chr6:30619443..30619450,-#_79a6708211b885bd34d9bea04e5ffea8p13@Tsga14
1.87e-86FFCP PHASE1:Mm9::chr3:100724698..100724706,+#_79a6708211b885bd34d9bea04e5ffea8p@chr3:100724698..100724706, +
1.87e-86FFCP PHASE2:Mm9::chr2:67011921..67011934,+#_79a6708211b885bd34d9bea04e5ffea8p2@Gm1322
1.87e-86FFCP PHASE2:Mm9::chr9:42207965..42207978,-#_79a6708211b885bd34d9bea04e5ffea8p5@Tecta
1.87e-86FFCP PHASE1:Mm9::chr8:13435173..13435186,+#_79a6708211b885bd34d9bea04e5ffea8p6@Fam70b
1.87e-86FFCP PHASE2:Mm9::chr1:172843847..172843880,-#_79a6708211b885bd34d9bea04e5ffea8p@chr1:172843847..172843880, -
1.87e-86FFCP PHASE1:Mm9::chr14:47293487..47293493,-#_79a6708211b885bd34d9bea04e5ffea8p@chr14:47293487..47293493, -
1.87e-86FFCP PHASE1:Mm9::chr11:89702580..89702593,-#_79a6708211b885bd34d9bea04e5ffea8p@chr11:89702580..89702593, -
1.87e-86FFCP PHASE2:Mm9::chr17:13983179..13983190,+#_79a6708211b885bd34d9bea04e5ffea8p@chr17:13983179..13983190, +
1.87e-86FFCP PHASE1:Mm9::chr9:42207965..42207978,-#_79a6708211b885bd34d9bea04e5ffea8p5@Tecta

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