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Revision as of 17:12, 15 June 2012

Name:seminiferous tubule of testis
Definition:"Seminiferous tubules are located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa. The epithelium of the tubule consists of sustentacular or Sertoli cells, which are tall, columnar type cells that line the tubule. In between the Sertoli cells are spermatogenic cells, which differentiate through meiosis to sperm cells. There are two types: convoluted and straight. convuluted towards the lateral side and straight as the tubule comes medially to form ducts which will exit the testis. [WP,unvetted]." [Wikipedia:Seminiferous_tubule]
Xrefs:
links:

AAO:0010399
BTO:0001235
EFO:0001404
EMAPA:18685
EMAPA:31476
EV:0100380
FMA:19825
GAID:400
[ 200px-Gray1145.png 200px-Gray1145.png]
MA:0000412
MAT:0000503
MESH:A.05.360.444.849.700
ncithesaurus:Seminiferous_Cord
ncithesaurus:Seminiferous_Tubule
SCTID:279614002
VHOG:0001363

XAO:0003088
Synonyms: "seminiferous cord" EXACT [EMAPA:18685]
"seminiferous tubule" EXACT []
"testis - seminiferous tubule" EXACT []
"tubuli seminiferi" EXACT []
Alt_id: UBERON:FMA_19825-XAO_0003088
Subset: uberon_slim

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0000058(duct),UBERON:0005904(duct of male reproductive system)
develops_from:UBERON:0005297(testis sex cord)
part_of:UBERON:0000473(testis)



Children

derives from:FF:0011471 (mouse epididymis and seminiferous tubule- neonate N30 sample),FF:0011506 (mouse epididymis and seminiferous tubule- neonate N00 sample)
part of:CL:0000216 (Sertoli cell),CL:0002625 (seminiferous tubule epithelial cell),UBERON:0004813 (seminiferous tubule epithelium)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology


Human (Homo sapiens)

Mouse (Mus musculus)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001343 (seminiferous tubule of testis), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data


P-valueFFCPShort description
5.42e-195FFCP PHASE2:Hg19::chr11:27721743..27721753,-#_e6177b5ebd3bd2c28f8f1044c677b99ap26@BDNF
5.42e-195FFCP PHASE1:Hg19::chr11:27721743..27721753,-#_e6177b5ebd3bd2c28f8f1044c677b99ap26@BDNF
9.37e-99FFCP PHASE1:Hg19::chr1:227505905..227505906,-#_c8728c8451df9bbfc7a2881358806779p43@CDC42BPA
9.37e-99FFCP PHASE1:Hg19::chr3:158450428..158450431,-#_c8728c8451df9bbfc7a2881358806779p9@RARRES1
9.37e-99FFCP PHASE2:Hg19::chr3:158450428..158450431,-#_c8728c8451df9bbfc7a2881358806779p9@RARRES1
9.37e-99FFCP PHASE2:Hg19::chr1:227505905..227505906,-#_c8728c8451df9bbfc7a2881358806779p43@CDC42BPA
2.55e-98FFCP PHASE2:Hg19::chr8:47529304..47529311,-#_1f4f956dd582857f6f9f5db61b258d5dp@chr8:47529304..47529311, -
2.55e-98FFCP PHASE2:Hg19::chr13:53030077..53030083,-#_1f4f956dd582857f6f9f5db61b258d5dp@chr13:53030077..53030083, -
2.55e-98FFCP PHASE1:Hg19::chr8:47529304..47529311,-#_1f4f956dd582857f6f9f5db61b258d5dp@chr8:47529304..47529311, -
2.55e-98FFCP PHASE2:Hg19::chr19:54600897..54600899,+#_1f4f956dd582857f6f9f5db61b258d5dp@chr19:54600897..54600899, +
2.55e-98FFCP PHASE2:Hg19::chr8:69832864..69832865,+#_1f4f956dd582857f6f9f5db61b258d5dp@chr8:69832864..69832865, +
2.55e-98FFCP PHASE1:Hg19::chr8:69832864..69832865,+#_1f4f956dd582857f6f9f5db61b258d5dp@chr8:69832864..69832865, +
2.55e-98FFCP PHASE2:Hg19::chr7:18206831..18206833,+#_1f4f956dd582857f6f9f5db61b258d5dp@chr7:18206831..18206833, +
2.55e-98FFCP PHASE1:Hg19::chr19:54600897..54600899,+#_1f4f956dd582857f6f9f5db61b258d5dp@chr19:54600897..54600899, +
2.55e-98FFCP PHASE2:Hg19::chr19:40320572..40320586,-#_1f4f956dd582857f6f9f5db61b258d5dp@chr19:40320572..40320586, -
2.55e-98FFCP PHASE1:Hg19::chr19:40320572..40320586,-#_1f4f956dd582857f6f9f5db61b258d5dp@chr19:40320572..40320586, -
2.55e-98FFCP PHASE1:Hg19::chr13:53030077..53030083,-#_1f4f956dd582857f6f9f5db61b258d5dp@chr13:53030077..53030083, -
2.55e-98FFCP PHASE2:Hg19::chr2:9519086..9519101,+#_1f4f956dd582857f6f9f5db61b258d5dp@chr2:9519086..9519101, +
2.55e-98FFCP PHASE2:Hg19::chr3:193356854..193356864,+#_1f4f956dd582857f6f9f5db61b258d5dp@chr3:193356854..193356864, +
2.55e-98FFCP PHASE1:Hg19::chr7:18206831..18206833,+#_1f4f956dd582857f6f9f5db61b258d5dp@chr7:18206831..18206833, +
2.55e-98FFCP PHASE1:Hg19::chr3:193356854..193356864,+#_1f4f956dd582857f6f9f5db61b258d5dp@chr3:193356854..193356864, +
2.55e-98FFCP PHASE2:Hg19::chr3:170430340..170430344,+#_1f4f956dd582857f6f9f5db61b258d5dp@chr3:170430340..170430344, +
2.55e-98FFCP PHASE1:Hg19::chr3:170430340..170430344,+#_1f4f956dd582857f6f9f5db61b258d5dp@chr3:170430340..170430344, +
2.55e-98FFCP PHASE1:Hg19::chr2:9519086..9519101,+#_1f4f956dd582857f6f9f5db61b258d5dp@chr2:9519086..9519101, +
2.55e-98FFCP PHASE2:Hg19::chr7:89874193..89874199,+#_1f4f956dd582857f6f9f5db61b258d5dp7@C7orf63
2.55e-98FFCP PHASE1:Hg19::chr7:89874193..89874199,+#_1f4f956dd582857f6f9f5db61b258d5dp7@C7orf63
1.23e-66FFCP PHASE2:Hg19::chr2:19551668..19551679,-#_48920e7f29a6b1768024e49874b8691fp@chr2:19551668..19551679, -
1.23e-66FFCP PHASE1:Hg19::chr2:19551668..19551679,-#_48920e7f29a6b1768024e49874b8691fp@chr2:19551668..19551679, -
2.39e-66FFCP PHASE2:Hg19::chr3:112931461..112931474,-#_d7348263c7f815cf58dcb1c080973a1fp@chr3:112931461..112931474, -
2.39e-66FFCP PHASE1:Hg19::chr12:15815732..15815744,-#_d7348263c7f815cf58dcb1c080973a1fp21@EPS8
2.39e-66FFCP PHASE2:Hg19::chr7:98445585..98445594,-#_d7348263c7f815cf58dcb1c080973a1fp22@TMEM130
2.39e-66FFCP PHASE1:Hg19::chr3:112931461..112931474,-#_d7348263c7f815cf58dcb1c080973a1fp@chr3:112931461..112931474, -
2.39e-66FFCP PHASE1:Hg19::chr7:98445585..98445594,-#_d7348263c7f815cf58dcb1c080973a1fp22@TMEM130
2.39e-66FFCP PHASE2:Hg19::chr1:197889533..197889548,+#_d7348263c7f815cf58dcb1c080973a1fp@chr1:197889533..197889548, +
2.39e-66FFCP PHASE1:Hg19::chr1:197889533..197889548,+#_d7348263c7f815cf58dcb1c080973a1fp@chr1:197889533..197889548, +
2.39e-66FFCP PHASE2:Hg19::chr2:72803155..72803204,-#_d7348263c7f815cf58dcb1c080973a1fp@chr2:72803155..72803204, -
2.39e-66FFCP PHASE1:Hg19::chr2:72803155..72803204,-#_d7348263c7f815cf58dcb1c080973a1fp@chr2:72803155..72803204, -
2.39e-66FFCP PHASE2:Hg19::chr12:15815732..15815744,-#_d7348263c7f815cf58dcb1c080973a1fp21@EPS8
4.66e-66FFCP PHASE2:Hg19::chr5:90830481..90830492,+#_583b5a2133afe5be76929d498d542e7ap@chr5:90830481..90830492, +
4.66e-66FFCP PHASE1:Hg19::chr5:90830481..90830492,+#_583b5a2133afe5be76929d498d542e7ap@chr5:90830481..90830492, +
4.66e-66FFCP PHASE1:Hg19::chr10:1034666..1034675,+#_583b5a2133afe5be76929d498d542e7ap4@GTPBP4
4.66e-66FFCP PHASE2:Hg19::chr21:48080873..48080878,+#_583b5a2133afe5be76929d498d542e7ap@chr21:48080873..48080878, +
4.66e-66FFCP PHASE2:Hg19::chr3:170916991..170916995,-#_583b5a2133afe5be76929d498d542e7ap@chr3:170916991..170916995, -
4.66e-66FFCP PHASE1:Hg19::chr3:170916991..170916995,-#_583b5a2133afe5be76929d498d542e7ap@chr3:170916991..170916995, -
4.66e-66FFCP PHASE1:Hg19::chr21:48080873..48080878,+#_583b5a2133afe5be76929d498d542e7ap@chr21:48080873..48080878, +
4.66e-66FFCP PHASE2:Hg19::chr10:1034666..1034675,+#_583b5a2133afe5be76929d498d542e7ap4@GTPBP4
4.66e-66FFCP PHASE2:Hg19::chr8:141728731..141728740,-#_583b5a2133afe5be76929d498d542e7ap38@PTK2
4.66e-66FFCP PHASE1:Hg19::chr8:141728731..141728740,-#_583b5a2133afe5be76929d498d542e7ap38@PTK2
4.66e-66FFCP PHASE2:Hg19::chr5:75912402..75912418,-#_583b5a2133afe5be76929d498d542e7ap@chr5:75912402..75912418, -
4.66e-66FFCP PHASE2:Hg19::chr3:99984127..99984138,+#_583b5a2133afe5be76929d498d542e7ap@chr3:99984127..99984138, +
4.66e-66FFCP PHASE1:Hg19::chr5:75912402..75912418,-#_583b5a2133afe5be76929d498d542e7ap@chr5:75912402..75912418, -
4.66e-66FFCP PHASE1:Hg19::chr3:99984127..99984138,+#_583b5a2133afe5be76929d498d542e7ap@chr3:99984127..99984138, +
6.41e-58FFCP PHASE2:Mm9::chr18:44264202..44264213,+#_c133c470e5acb18ed9dad64cfc831adfp4@Spink12
6.41e-58FFCP PHASE1:Mm9::chr18:44264202..44264213,+#_c133c470e5acb18ed9dad64cfc831adfp4@Spink12
1.46e-50FFCP PHASE2:Hg19::chr6:134210772..134210782,+#_5adea3f77ed382f8a04ddefefabb1033p8@TCF21
1.46e-50FFCP PHASE1:Hg19::chr6:134210772..134210782,+#_5adea3f77ed382f8a04ddefefabb1033p8@TCF21
1.46e-50FFCP PHASE2:Hg19::chr11:114173606..114173612,+#_5adea3f77ed382f8a04ddefefabb1033p@chr11:114173606..114173612, +
1.46e-50FFCP PHASE2:Hg19::chr2:177009137..177009140,+#_5adea3f77ed382f8a04ddefefabb1033p@chr2:177009137..177009140, +
1.46e-50FFCP PHASE1:Hg19::chr2:177009137..177009140,+#_5adea3f77ed382f8a04ddefefabb1033p@chr2:177009137..177009140, +
1.46e-50FFCP PHASE1:Hg19::chr11:114173606..114173612,+#_5adea3f77ed382f8a04ddefefabb1033p@chr11:114173606..114173612, +
2.42e-50FFCP PHASE2:Hg19::chr21:17214724..17214740,+#_0826d2eba7af8961233437fbcf5b629fp11@USP25
2.42e-50FFCP PHASE2:Hg19::chr2:55459485..55459491,-#_0826d2eba7af8961233437fbcf5b629fp6@C2orf63
2.42e-50FFCP PHASE1:Hg19::chr19:54024454..54024463,+#_0826d2eba7af8961233437fbcf5b629fp31@ZNF331
2.42e-50FFCP PHASE1:Hg19::chr21:17214724..17214740,+#_0826d2eba7af8961233437fbcf5b629fp11@USP25
2.42e-50FFCP PHASE1:Hg19::chr2:55459485..55459491,-#_0826d2eba7af8961233437fbcf5b629fp6@C2orf63
2.42e-50FFCP PHASE2:Hg19::chr15:39288691..39288698,+#_0826d2eba7af8961233437fbcf5b629fp@chr15:39288691..39288698, +
2.42e-50FFCP PHASE2:Hg19::chr5:144875561..144875565,+#_0826d2eba7af8961233437fbcf5b629fp@chr5:144875561..144875565, +
2.42e-50FFCP PHASE2:Hg19::chr7:137564648..137564658,-#_0826d2eba7af8961233437fbcf5b629fp32@CREB3L2
2.42e-50FFCP PHASE1:Hg19::chr15:39288691..39288698,+#_0826d2eba7af8961233437fbcf5b629fp@chr15:39288691..39288698, +
2.42e-50FFCP PHASE2:Hg19::chr3:46477553..46477563,-#_0826d2eba7af8961233437fbcf5b629fp@chr3:46477553..46477563, -
2.42e-50FFCP PHASE2:Hg19::chr19:54024454..54024463,+#_0826d2eba7af8961233437fbcf5b629fp31@ZNF331
2.42e-50FFCP PHASE1:Hg19::chr5:144875561..144875565,+#_0826d2eba7af8961233437fbcf5b629fp@chr5:144875561..144875565, +
2.42e-50FFCP PHASE1:Hg19::chr3:46477553..46477563,-#_0826d2eba7af8961233437fbcf5b629fp@chr3:46477553..46477563, -
2.42e-50FFCP PHASE1:Hg19::chr7:137564648..137564658,-#_0826d2eba7af8961233437fbcf5b629fp32@CREB3L2
3.99e-50FFCP PHASE2:Hg19::chr11:829412..829430,+#_5bb3bb3a52e2ebfe02e666b89c2181f2p11@EFCAB4A
3.99e-50FFCP PHASE1:Hg19::chr12:5198350..5198359,+#_5bb3bb3a52e2ebfe02e666b89c2181f2p@chr12:5198350..5198359, +
3.99e-50FFCP PHASE1:Hg19::chr15:39420650..39420666,+#_5bb3bb3a52e2ebfe02e666b89c2181f2p@chr15:39420650..39420666, +
3.99e-50FFCP PHASE1:Hg19::chr14:64804787..64804796,-#_5bb3bb3a52e2ebfe02e666b89c2181f2p10@ESR2
3.99e-50FFCP PHASE1:Hg19::chr11:829412..829430,+#_5bb3bb3a52e2ebfe02e666b89c2181f2p11@EFCAB4A
3.99e-50FFCP PHASE2:Hg19::chr4:103969123..103969127,-#_5bb3bb3a52e2ebfe02e666b89c2181f2p@chr4:103969123..103969127, -
3.99e-50FFCP PHASE1:Hg19::chr4:103969123..103969127,-#_5bb3bb3a52e2ebfe02e666b89c2181f2p@chr4:103969123..103969127, -
3.99e-50FFCP PHASE2:Hg19::chr12:5198350..5198359,+#_5bb3bb3a52e2ebfe02e666b89c2181f2p@chr12:5198350..5198359, +
3.99e-50FFCP PHASE2:Hg19::chr14:64804787..64804796,-#_5bb3bb3a52e2ebfe02e666b89c2181f2p10@ESR2
3.99e-50FFCP PHASE2:Hg19::chr15:39420650..39420666,+#_5bb3bb3a52e2ebfe02e666b89c2181f2p@chr15:39420650..39420666, +
6.58e-50FFCP PHASE1:Hg19::chr16:1203194..1203207,+#_ff8dc9874e9032fddac9acf0ea43c4f8p3@CACNA1H
6.58e-50FFCP PHASE2:Hg19::chr14:50697797..50697820,-#_ff8dc9874e9032fddac9acf0ea43c4f8p13@SOS2
6.58e-50FFCP PHASE2:Hg19::chr17:58165788..58165794,-#_ff8dc9874e9032fddac9acf0ea43c4f8p1@LOC645638
6.58e-50FFCP PHASE2:Hg19::chr7:92462738..92462749,-#_ff8dc9874e9032fddac9acf0ea43c4f8p51@CDK6
6.58e-50FFCP PHASE1:Hg19::chr7:92462738..92462749,-#_ff8dc9874e9032fddac9acf0ea43c4f8p51@CDK6
6.58e-50FFCP PHASE2:Hg19::chr16:1203194..1203207,+#_ff8dc9874e9032fddac9acf0ea43c4f8p3@CACNA1H
6.58e-50FFCP PHASE1:Hg19::chr14:50697797..50697820,-#_ff8dc9874e9032fddac9acf0ea43c4f8p13@SOS2
6.58e-50FFCP PHASE1:Hg19::chr17:58165788..58165794,-#_ff8dc9874e9032fddac9acf0ea43c4f8p1@LOC645638
4.52e-44FFCP PHASE2:Mm9::chr17:75581992..75582009,+#_5b2fed591b04b97e73acb4dcf8a3dbabp@chr17:75581992..75582009, +
4.52e-44FFCP PHASE1:Mm9::chr17:75581992..75582009,+#_5b2fed591b04b97e73acb4dcf8a3dbabp@chr17:75581992..75582009, +
6.62e-41FFCP PHASE2:Hg19::chr3:194214959..194214968,-#_97edfc0aac2af46dfb0732d3a12b0141p@chr3:194214959..194214968, -
6.62e-41FFCP PHASE1:Hg19::chr3:194214959..194214968,-#_97edfc0aac2af46dfb0732d3a12b0141p@chr3:194214959..194214968, -
9.91e-41FFCP PHASE1:Hg19::chr15:34522001..34522013,+#_6bf59b44454d936bf3f722a33563cf9ep@chr15:34522001..34522013, +
9.91e-41FFCP PHASE1:Hg19::chr13:49549473..49549480,+#_6bf59b44454d936bf3f722a33563cf9ep@chr13:49549473..49549480, +
9.91e-41FFCP PHASE2:Hg19::chr11:110581726..110581728,-#_6bf59b44454d936bf3f722a33563cf9ep@chr11:110581726..110581728, -
9.91e-41FFCP PHASE2:Hg19::chr2:102604493..102604499,+#_6bf59b44454d936bf3f722a33563cf9ep@chr2:102604493..102604499, +