Novel motif:65

name:	motif65_TNGCGA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0006396	RNA processing	1.970124e-11
GO:0034660	ncRNA metabolic process	2.146778e-11
GO:0034470	ncRNA processing	3.375181e-11
GO:0045116	protein neddylation	1.034544e-10
GO:0022613	ribonucleoprotein complex biogenesis	5.535259e-9
GO:0016180	snRNA processing	8.047392e-9
GO:0043543	protein acylation	9.629253e-9
GO:0000414	regulation of histone H3-K36 methylation	1.300118e-8
GO:0046491	L-methylmalonyl-CoA metabolic process	2.510779e-8
GO:0000375	RNA splicing, via transesterification reactions	3.287738e-8
GO:0016570	histone modification	4.580263e-8
GO:0016569	covalent chromatin modification	5.059332e-8
GO:0006473	protein acetylation	5.648951e-8
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	8.888637e-8
GO:0030433	ER-associated protein catabolic process	9.934045e-8
GO:0016073	snRNA metabolic process	1.165964e-7
GO:0000416	positive regulation of histone H3-K36 methylation	1.398735e-7
GO:0032784	regulation of transcription elongation, DNA-dependent	1.506243e-7
GO:0006353	transcription termination, DNA-dependent	1.713673e-7
GO:0006475	internal protein amino acid acetylation	1.936192e-7
GO:0006281	DNA repair	2.073519e-7
GO:0006415	translational termination	2.266165e-7
GO:0006370	mRNA capping	2.752967e-7
GO:0015817	histidine transport	3.564809e-7
GO:0071843	cellular component biogenesis at cellular level	3.806995e-7
GO:0010225	response to UV-C	5.948423e-7
GO:0030970	retrograde protein transport, ER to cytosol	6.422007e-7
GO:0016573	histone acetylation	6.484867e-7
GO:0000398	nuclear mRNA splicing, via spliceosome	7.179458e-7
GO:0060023	soft palate development	8.613986e-7
GO:0016070	RNA metabolic process	9.170926e-7
GO:0032259	methylation	1.032176e-6
GO:0006369	termination of RNA polymerase II transcription	1.224486e-6
GO:0090304	nucleic acid metabolic process	1.346556e-6
GO:0042538	hyperosmotic salinity response	1.490497e-6
GO:0018394	peptidyl-lysine acetylation	1.532568e-6
GO:0009452	RNA capping	1.653008e-6
GO:0090083	regulation of inclusion body assembly	1.838462e-6
GO:0018393	internal peptidyl-lysine acetylation	2.176165e-6
GO:0006189	'de novo' IMP biosynthetic process	2.326595e-6
GO:0043415	positive regulation of skeletal muscle tissue regeneration	2.529457e-6
GO:0015742	alpha-ketoglutarate transport	2.529457e-6
GO:0043503	skeletal muscle fiber adaptation	2.544205e-6
GO:0006481	C-terminal protein methylation	2.546979e-6
GO:0043624	cellular protein complex disassembly	2.861650e-6
GO:0042776	mitochondrial ATP synthesis coupled proton transport	3.006836e-6
GO:0019083	viral transcription	3.302082e-6
GO:0006354	transcription elongation, DNA-dependent	3.487939e-6
GO:0051095	regulation of helicase activity	3.984984e-6
GO:0008033	tRNA processing	4.127689e-6
GO:0046755	non-lytic virus budding	4.150157e-6
GO:0042073	intraflagellar transport	4.150157e-6
GO:0016071	mRNA metabolic process	4.371010e-6
GO:0034623	cellular macromolecular complex disassembly	5.629841e-6
GO:0006172	ADP biosynthetic process	5.645781e-6
GO:0033205	cell cycle cytokinesis	5.802148e-6
GO:0042254	ribosome biogenesis	6.612168e-6
GO:0046853	inositol or phosphatidylinositol phosphorylation	6.723741e-6
GO:0006289	nucleotide-excision repair	6.816506e-6
GO:0061084	negative regulation of protein refolding	6.864985e-6
GO:0035621	ER to Golgi ceramide transport	6.968379e-6
GO:0042274	ribosomal small subunit biogenesis	8.274939e-6
GO:0042696	menarche	9.032583e-6
GO:0051292	nuclear pore complex assembly	9.207882e-6
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	1.114864e-5
GO:0071826	ribonucleoprotein complex subunit organization	1.123173e-5
GO:0016072	rRNA metabolic process	1.232935e-5
GO:0043241	protein complex disassembly	1.320310e-5
GO:0010467	gene expression	1.422359e-5
GO:0022618	ribonucleoprotein complex assembly	1.468032e-5
GO:0002679	respiratory burst involved in defense response	1.703128e-5
GO:0070625	zymogen granule exocytosis	1.712417e-5
GO:0035721	intraflagellar retrograde transport	1.778714e-5
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	2.025819e-5
GO:0032984	macromolecular complex disassembly	2.090538e-5
GO:0051028	mRNA transport	2.098009e-5
GO:0006545	glycine biosynthetic process	2.287704e-5
GO:0060996	dendritic spine development	2.574330e-5
GO:0006379	mRNA cleavage	2.583146e-5
GO:0006479	protein methylation	2.838367e-5
GO:0006406	mRNA export from nucleus	2.984688e-5
GO:0006325	chromatin organization	3.511889e-5
GO:0050434	positive regulation of viral transcription	3.576898e-5
GO:0051096	positive regulation of helicase activity	3.788343e-5
GO:0008380	RNA splicing	3.898158e-5
GO:0016568	chromatin modification	3.908303e-5
GO:0006297	nucleotide-excision repair, DNA gap filling	4.163128e-5
GO:0006368	transcription elongation from RNA polymerase II promoter	4.174219e-5
GO:0043622	cortical microtubule organization	4.258879e-5
GO:0021528	commissural neuron differentiation in spinal cord	4.258879e-5
GO:0030103	vasopressin secretion	4.258879e-5
GO:0015986	ATP synthesis coupled proton transport	4.347799e-5
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	4.464357e-5
GO:0061032	visceral serous pericardium development	4.464357e-5
GO:0042759	long-chain fatty acid biosynthetic process	4.704180e-5
GO:0071394	cellular response to testosterone stimulus	4.716716e-5
GO:0006414	translational elongation	5.352083e-5
GO:0071545	inositol phosphate catabolic process	5.483473e-5
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	5.796175e-5
GO:0006730	one-carbon metabolic process	6.149307e-5
GO:0044265	cellular macromolecule catabolic process	6.296226e-5
GO:0002149	hypochlorous acid biosynthetic process	6.562678e-5
GO:0046105	thymidine biosynthetic process	6.671312e-5
GO:0060465	pharynx development	6.671312e-5
GO:0043414	macromolecule methylation	6.703318e-5
GO:0048813	dendrite morphogenesis	6.847374e-5
GO:0021759	globus pallidus development	7.405545e-5
GO:0051568	histone H3-K4 methylation	7.679452e-5
GO:0051289	protein homotetramerization	7.831454e-5
GO:0034645	cellular macromolecule biosynthetic process	7.840323e-5
GO:0019941	modification-dependent protein catabolic process	8.663674e-5
GO:0031081	nuclear pore distribution	8.724249e-5
GO:0006412	translation	9.501512e-5
GO:0006511	ubiquitin-dependent protein catabolic process	9.679580e-5
GO:0006188	IMP biosynthetic process	9.764276e-5
GO:0002003	angiotensin maturation	1.006598e-4
GO:0043632	modification-dependent macromolecule catabolic process	1.014731e-4
GO:0019673	GDP-mannose metabolic process	1.040475e-4
GO:0000725	recombinational repair	1.049107e-4
GO:0021603	cranial nerve formation	1.053813e-4
GO:0001945	lymph vessel development	1.162236e-4
GO:0035722	interleukin-12-mediated signaling pathway	1.170301e-4
GO:0042026	protein refolding	1.250107e-4
GO:0072166	posterior mesonephric tubule development	1.301932e-4
GO:0018205	peptidyl-lysine modification	1.442229e-4
GO:0032793	positive regulation of CREB transcription factor activity	1.639550e-4
GO:0048199	vesicle targeting, to, from or within Golgi	1.665744e-4
GO:0001676	long-chain fatty acid metabolic process	1.670607e-4
GO:0006283	transcription-coupled nucleotide-excision repair	1.732336e-4
GO:0060997	dendritic spine morphogenesis	1.956369e-4
GO:0035470	positive regulation of vascular wound healing	2.078184e-4
GO:0051603	proteolysis involved in cellular protein catabolic process	2.195814e-4
GO:0006413	translational initiation	2.199664e-4
GO:0006772	thiamine metabolic process	2.454854e-4
GO:0035507	regulation of myosin-light-chain-phosphatase activity	2.481680e-4
GO:0007231	osmosensory signaling pathway	2.481680e-4
GO:0006173	dADP biosynthetic process	2.559307e-4
GO:0006901	vesicle coating	2.627443e-4
GO:0001732	formation of translation initiation complex	2.708394e-4
GO:0034968	histone lysine methylation	2.720924e-4
GO:0006364	rRNA processing	2.764943e-4
GO:0014908	myotube differentiation involved in skeletal muscle regeneration	2.774771e-4
GO:0042450	arginine biosynthetic process via ornithine	2.774771e-4
GO:0051276	chromosome organization	2.779024e-4
GO:0030208	dermatan sulfate biosynthetic process	2.902396e-4
GO:0000022	mitotic spindle elongation	2.902396e-4
GO:0032774	RNA biosynthetic process	2.965367e-4
GO:0016571	histone methylation	3.106189e-4
GO:0046434	organophosphate catabolic process	3.130594e-4
GO:0070672	response to interleukin-15	3.160625e-4
GO:0060849	regulation of transcription involved in lymphatic endothelial cell fate commitment	3.244747e-4
GO:0009304	tRNA transcription	3.264977e-4
GO:0009386	translational attenuation	3.280086e-4
GO:0000724	double-strand break repair via homologous recombination	3.328140e-4
GO:0006013	mannose metabolic process	3.367862e-4
GO:0042508	tyrosine phosphorylation of Stat1 protein	3.800939e-4
GO:0046855	inositol phosphate dephosphorylation	3.857902e-4
GO:0042723	thiamine-containing compound metabolic process	3.911598e-4
GO:2000117	negative regulation of cysteine-type endopeptidase activity	3.985458e-4
GO:0072298	regulation of metanephric glomerulus development	3.991779e-4
GO:0032786	positive regulation of transcription elongation, DNA-dependent	3.991779e-4
GO:0022601	menstrual cycle phase	4.215164e-4
GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	4.261838e-4
GO:0071557	histone H3-K27 demethylation	4.292198e-4
GO:0035574	histone H4-K20 demethylation	4.292198e-4
GO:0006310	DNA recombination	4.389581e-4
GO:0016575	histone deacetylation	4.407037e-4
GO:0043501	skeletal muscle adaptation	4.509983e-4
GO:0043966	histone H3 acetylation	4.593608e-4
GO:0009059	macromolecule biosynthetic process	4.615120e-4
GO:2000195	negative regulation of female gonad development	4.627951e-4
GO:0006397	mRNA processing	4.880457e-4
GO:0014813	satellite cell commitment	4.965693e-4
GO:0006051	N-acetylmannosamine metabolic process	4.965693e-4
GO:0080154	regulation of fertilization	5.142921e-4
GO:0035724	CD24 biosynthetic process	5.142921e-4
GO:2000438	negative regulation of monocyte extravasation	5.142921e-4
GO:0035723	interleukin-15-mediated signaling pathway	5.142921e-4
GO:0035229	positive regulation of glutamate-cysteine ligase activity	5.142921e-4
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	5.184687e-4
GO:0090084	negative regulation of inclusion body assembly	5.425770e-4
GO:2000194	regulation of female gonad development	5.436820e-4
GO:0042278	purine nucleoside metabolic process	5.477261e-4
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	5.941430e-4
GO:0006476	protein deacetylation	6.100544e-4
GO:0016926	protein desumoylation	6.148990e-4
GO:0048532	anatomical structure arrangement	6.336212e-4
GO:0060923	cardiac muscle cell fate commitment	6.495078e-4
GO:0010626	negative regulation of Schwann cell proliferation	6.711008e-4
GO:0060839	endothelial cell fate commitment	6.711008e-4
GO:0044257	cellular protein catabolic process	7.045268e-4
GO:0060399	positive regulation of growth hormone receptor signaling pathway	7.080819e-4
GO:0007422	peripheral nervous system development	7.109313e-4
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	7.169818e-4
GO:0003406	retinal pigment epithelium development	7.178850e-4
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	7.542794e-4
GO:0051569	regulation of histone H3-K4 methylation	7.607480e-4
GO:0003341	cilium movement	8.369492e-4
GO:0065001	specification of axis polarity	8.873834e-4
GO:0061157	mRNA destabilization	8.958412e-4
GO:0045090	retroviral genome replication	8.958412e-4
GO:0006450	regulation of translational fidelity	8.958412e-4
GO:0008295	spermidine biosynthetic process	8.958412e-4
GO:0010609	posttranscriptional regulation of gene expression by mRNA localization	8.958412e-4
GO:0035601	protein deacylation	9.083200e-4
GO:0006420	arginyl-tRNA aminoacylation	9.145122e-4
GO:0006366	transcription from RNA polymerase II promoter	9.160452e-4
GO:0046323	glucose import	9.209699e-4
GO:0007141	male meiosis I	9.251359e-4
GO:0010498	proteasomal protein catabolic process	9.481117e-4
GO:0042503	tyrosine phosphorylation of Stat3 protein	9.516440e-4
GO:0014034	neural crest cell fate commitment	9.910947e-4
GO:0006399	tRNA metabolic process	9.970495e-4
GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	1.002087e-3
GO:0009057	macromolecule catabolic process	1.011587e-3
GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter	1.032023e-3
GO:0006346	methylation-dependent chromatin silencing	1.060286e-3
GO:0006271	DNA strand elongation involved in DNA replication	1.074770e-3
GO:0046782	regulation of viral transcription	1.129122e-3
GO:0032425	positive regulation of mismatch repair	1.137516e-3
GO:0016344	meiotic chromosome movement towards spindle pole	1.137516e-3
GO:0001842	neural fold formation	1.137516e-3
GO:0034498	early endosome to Golgi transport	1.149215e-3
GO:0010833	telomere maintenance via telomere lengthening	1.155868e-3
GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation	1.166511e-3
GO:0048205	COPI coating of Golgi vesicle	1.166511e-3
GO:0043647	inositol phosphate metabolic process	1.184458e-3
GO:0034625	fatty acid elongation, monounsaturated fatty acid	1.202568e-3
GO:0015993	molecular hydrogen transport	1.231425e-3
GO:0006513	protein monoubiquitination	1.244361e-3
GO:0000389	nuclear mRNA 3'-splice site recognition	1.251692e-3
GO:0007518	myoblast cell fate determination	1.263173e-3
GO:0006405	RNA export from nucleus	1.272197e-3
GO:0021871	forebrain regionalization	1.313946e-3
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	1.355151e-3
GO:0060177	regulation of angiotensin metabolic process	1.355151e-3
GO:0022616	DNA strand elongation	1.362726e-3
GO:0032298	positive regulation of DNA-dependent DNA replication initiation	1.376029e-3
GO:0018916	nitrobenzene metabolic process	1.376029e-3
GO:0014037	Schwann cell differentiation	1.421717e-3
GO:0032201	telomere maintenance via semi-conservative replication	1.428130e-3
GO:0042506	tyrosine phosphorylation of Stat5 protein	1.468033e-3
GO:0006900	membrane budding	1.499056e-3
GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity	1.517346e-3
GO:0060304	regulation of phosphatidylinositol dephosphorylation	1.517346e-3
GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process	1.517346e-3
GO:0007634	optokinetic behavior	1.517346e-3
GO:0021599	abducens nerve formation	1.517346e-3
GO:0031119	tRNA pseudouridine synthesis	1.517346e-3
GO:0048208	COPII vesicle coating	1.636694e-3
GO:0046502	uroporphyrinogen III metabolic process	1.711476e-3
GO:0009956	radial pattern formation	1.715179e-3
GO:0032055	negative regulation of translation in response to stress	1.740327e-3
GO:0006401	RNA catabolic process	1.793950e-3
GO:0018192	enzyme active site formation via L-cysteine persulfide	1.818927e-3
GO:0042255	ribosome assembly	1.833404e-3
GO:0009226	nucleotide-sugar biosynthetic process	1.847219e-3
GO:0006684	sphingomyelin metabolic process	1.901335e-3
GO:0042351	'de novo' GDP-L-fucose biosynthetic process	1.944929e-3
GO:2000786	positive regulation of autophagic vacuole assembly	2.043547e-3
GO:0070537	histone H2A K63-linked deubiquitination	2.043547e-3
GO:0002268	follicular dendritic cell differentiation	2.048673e-3
GO:0006903	vesicle targeting	2.098978e-3
GO:0022011	myelination in peripheral nervous system	2.103453e-3
GO:0031584	activation of phospholipase D activity	2.120297e-3
GO:0017148	negative regulation of translation	2.146544e-3
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	2.222615e-3
GO:0000715	nucleotide-excision repair, DNA damage recognition	2.222615e-3
GO:0010587	miRNA catabolic process	2.278564e-3
GO:0009258	10-formyltetrahydrofolate catabolic process	2.278564e-3
GO:0009225	nucleotide-sugar metabolic process	2.295225e-3
GO:0009303	rRNA transcription	2.362925e-3
GO:0034214	protein hexamerization	2.367404e-3
GO:0045830	positive regulation of isotype switching	2.386285e-3
GO:0035565	regulation of pronephros size	2.409349e-3
GO:0039020	pronephric nephron tubule development	2.409349e-3
GO:0072284	metanephric S-shaped body morphogenesis	2.426656e-3
GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity	2.501996e-3
GO:0046604	positive regulation of mitotic centrosome separation	2.503115e-3
GO:0043048	dolichyl monophosphate biosynthetic process	2.503115e-3
GO:0002175	protein localization to paranode region of axon	2.503115e-3
GO:0051168	nuclear export	2.537050e-3
GO:0006895	Golgi to endosome transport	2.656011e-3
GO:0048194	Golgi vesicle budding	2.703634e-3
GO:0007213	muscarinic acetylcholine receptor signaling pathway	2.739515e-3
GO:0048266	behavioral response to pain	2.740787e-3
GO:0003339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	2.744910e-3
GO:0032922	circadian regulation of gene expression	2.761279e-3
GO:0018243	protein O-linked glycosylation via threonine	2.780909e-3
GO:0018242	protein O-linked glycosylation via serine	2.780909e-3
GO:0030163	protein catabolic process	2.787357e-3
GO:0061383	trabecula morphogenesis	2.818392e-3
GO:0000415	negative regulation of histone H3-K36 methylation	2.862236e-3
GO:0006986	response to unfolded protein	2.897468e-3
GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter	2.916530e-3
GO:0019367	fatty acid elongation, saturated fatty acid	2.916530e-3
GO:0060466	activation of meiosis involved in egg activation	2.916530e-3
GO:0000018	regulation of DNA recombination	3.116810e-3
GO:0048343	paraxial mesodermal cell fate commitment	3.118690e-3
GO:0061384	heart trabecular morphogenesis	3.248882e-3
GO:0031123	RNA 3'-end processing	3.313556e-3
GO:0040038	polar body extrusion after meiotic divisions	3.331754e-3
GO:0021571	rhombomere 5 development	3.338484e-3
GO:0009648	photoperiodism	3.423048e-3
GO:0006352	transcription initiation, DNA-dependent	3.488436e-3
GO:0021754	facial nucleus development	3.506382e-3
GO:0007090	regulation of S phase of mitotic cell cycle	3.530651e-3
GO:0048665	neuron fate specification	3.551495e-3
GO:0031124	mRNA 3'-end processing	3.589465e-3
GO:0070544	histone H3-K36 demethylation	3.614669e-3
GO:0045911	positive regulation of DNA recombination	3.669305e-3
GO:0060836	lymphatic endothelial cell differentiation	3.829156e-3
GO:0043153	entrainment of circadian clock by photoperiod	3.845120e-3
GO:0035022	positive regulation of Rac protein signal transduction	3.845120e-3
GO:0042780	tRNA 3'-end processing	3.874193e-3
GO:0048702	embryonic neurocranium morphogenesis	4.005577e-3
GO:0000722	telomere maintenance via recombination	4.038136e-3
GO:0032070	regulation of deoxyribonuclease activity	4.085443e-3
GO:0047484	regulation of response to osmotic stress	4.085443e-3
GO:0060271	cilium morphogenesis	4.090177e-3
GO:0051882	mitochondrial depolarization	4.175237e-3
GO:0006424	glutamyl-tRNA aminoacylation	4.175237e-3
GO:0006287	base-excision repair, gap-filling	4.383748e-3
GO:0006302	double-strand break repair	4.566086e-3
GO:0072044	collecting duct development	4.609452e-3
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	4.666472e-3
GO:0006596	polyamine biosynthetic process	4.666514e-3
GO:0009153	purine deoxyribonucleotide biosynthetic process	4.700355e-3
GO:0001826	inner cell mass cell differentiation	4.700355e-3
GO:0021604	cranial nerve structural organization	4.751263e-3
GO:0032785	negative regulation of transcription elongation, DNA-dependent	4.768491e-3
GO:0060419	heart growth	4.844234e-3
GO:2000824	negative regulation of androgen receptor activity	4.867840e-3
GO:0071048	nuclear retention of unspliced pre-mRNA at the site of transcription	4.867840e-3
GO:0043308	eosinophil degranulation	4.867840e-3
GO:0033594	response to hydroxyisoflavone	4.867840e-3
GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine	4.908549e-3
GO:0044240	multicellular organismal lipid catabolic process	4.909813e-3
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	4.917223e-3
GO:0014044	Schwann cell development	4.980247e-3
GO:0071108	protein K48-linked deubiquitination	5.029054e-3
GO:2000597	positive regulation of optic nerve formation	5.344391e-3
GO:0061360	optic chiasma development	5.344391e-3
GO:0021633	optic nerve structural organization	5.344391e-3
GO:0021650	vestibulocochlear nerve formation	5.344391e-3
GO:0035799	ureter maturation	5.344391e-3
GO:0048102	autophagic cell death	5.413171e-3
GO:0003017	lymph circulation	5.425076e-3
GO:0034661	ncRNA catabolic process	5.494731e-3
GO:0060038	cardiac muscle cell proliferation	5.518126e-3
GO:0019852	L-ascorbic acid metabolic process	5.547381e-3
GO:0006403	RNA localization	5.551187e-3
GO:0021612	facial nerve structural organization	5.613770e-3
GO:0044260	cellular macromolecule metabolic process	5.626184e-3
GO:0050684	regulation of mRNA processing	5.649560e-3
GO:0060017	parathyroid gland development	5.688978e-3
GO:0035083	cilium axoneme assembly	5.699557e-3
GO:0060459	left lung development	5.749723e-3
GO:0044258	intestinal lipid catabolic process	5.791286e-3
GO:0018350	protein esterification	5.791286e-3
GO:0021569	rhombomere 3 development	5.936861e-3
GO:0014029	neural crest formation	5.936861e-3
GO:0048524	positive regulation of viral reproduction	6.197924e-3
GO:0006367	transcription initiation from RNA polymerase II promoter	6.245441e-3
GO:0007260	tyrosine phosphorylation of STAT protein	6.251622e-3
GO:0045113	regulation of integrin biosynthetic process	6.253436e-3
GO:0021892	cerebral cortex GABAergic interneuron differentiation	6.283843e-3
GO:0051571	positive regulation of histone H3-K4 methylation	6.287555e-3
GO:0072148	epithelial cell fate commitment	6.324097e-3
GO:0009070	serine family amino acid biosynthetic process	6.377557e-3
GO:0030539	male genitalia development	6.408387e-3
GO:0048298	positive regulation of isotype switching to IgA isotypes	6.484292e-3
GO:0006867	asparagine transport	6.514205e-3
GO:0070904	transepithelial L-ascorbic acid transport	6.532133e-3
GO:0045083	negative regulation of interleukin-12 biosynthetic process	6.532133e-3
GO:0045947	negative regulation of translational initiation	6.589487e-3
GO:0060708	spongiotrophoblast differentiation	6.663742e-3
GO:0045750	positive regulation of S phase of mitotic cell cycle	6.749244e-3
GO:0015959	diadenosine polyphosphate metabolic process	6.858537e-3
GO:0007197	inhibition of adenylate cyclase activity by muscarinic acetylcholine receptor signaling pathway	6.874040e-3
GO:0018216	peptidyl-arginine methylation	6.884791e-3
GO:0060298	positive regulation of sarcomere organization	6.948883e-3
GO:0031055	chromatin remodeling at centromere	6.952511e-3
GO:0070370	cellular heat acclimation	7.075789e-3
GO:0071169	establishment of protein localization to chromatin	7.075789e-3
GO:0009436	glyoxylate catabolic process	7.075789e-3
GO:0000056	ribosomal small subunit export from nucleus	7.075789e-3
GO:0006351	transcription, DNA-dependent	7.328876e-3
GO:0035409	histone H3-Y41 phosphorylation	7.383139e-3
GO:0044088	regulation of vacuole organization	7.383139e-3
GO:0008636	activation of caspase activity by protein phosphorylation	7.383139e-3
GO:0008216	spermidine metabolic process	7.383139e-3
GO:0010172	embryonic body morphogenesis	7.417795e-3
GO:0006499	N-terminal protein myristoylation	7.428982e-3
GO:0060039	pericardium development	7.459951e-3
GO:0060297	regulation of sarcomere organization	7.485681e-3
GO:0035020	regulation of Rac protein signal transduction	7.559439e-3
GO:0014888	striated muscle adaptation	7.590031e-3
GO:0032057	negative regulation of translational initiation in response to stress	7.675371e-3
GO:0032203	telomere formation via telomerase	7.745028e-3
GO:0010956	negative regulation of calcidiol 1-monooxygenase activity	7.876957e-3
GO:0006284	base-excision repair	7.882468e-3
GO:0060343	trabecula formation	7.922871e-3
GO:0050658	RNA transport	8.127330e-3
GO:0051461	positive regulation of corticotropin secretion	8.190291e-3
GO:0060398	regulation of growth hormone receptor signaling pathway	8.193650e-3
GO:0048793	pronephros development	8.328162e-3
GO:0021561	facial nerve development	8.541519e-3
GO:0045714	regulation of low-density lipoprotein particle receptor biosynthetic process	8.801205e-3
GO:0015884	folic acid transport	9.134293e-3
GO:0070171	negative regulation of tooth mineralization	9.158455e-3
GO:0046543	development of secondary female sexual characteristics	9.311163e-3
GO:0042797	tRNA transcription from RNA polymerase III promoter	9.417622e-3
GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter	9.417622e-3
GO:0046602	regulation of mitotic centrosome separation	9.439792e-3
GO:0000921	septin ring assembly	9.506901e-3
GO:0006505	GPI anchor metabolic process	9.620987e-3
GO:0035732	nitric oxide storage	9.637241e-3
GO:0042407	cristae formation	9.637241e-3
GO:0035726	common myeloid progenitor cell proliferation	9.637241e-3
GO:0071638	negative regulation of monocyte chemotactic protein-1 production	9.637241e-3
GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	9.637241e-3
GO:0003257	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation	9.637241e-3
GO:0000073	spindle pole body separation	9.637241e-3
GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	9.637241e-3
GO:0071845	cellular component disassembly at cellular level	9.662519e-3
GO:0042268	regulation of cytolysis	9.828321e-3
GO:0033261	regulation of S phase	9.925792e-3
GO:0090303	positive regulation of wound healing	1.000027e-2
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	1.002268e-2
GO:0070389	chaperone cofactor-dependent protein refolding	1.003151e-2
GO:0015879	carnitine transport	1.005771e-2
GO:0055017	cardiac muscle tissue growth	1.006492e-2
GO:0030488	tRNA methylation	1.012170e-2
GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA	1.012170e-2
GO:0042094	interleukin-2 biosynthetic process	1.015334e-2
GO:0006536	glutamate metabolic process	1.030909e-2
GO:0010624	regulation of Schwann cell proliferation	1.033265e-2
GO:0043967	histone H4 acetylation	1.038481e-2
GO:0042167	heme catabolic process	1.039608e-2
GO:0021610	facial nerve morphogenesis	1.039608e-2
GO:0008625	induction of apoptosis via death domain receptors	1.067301e-2
GO:0032423	regulation of mismatch repair	1.071539e-2
GO:0035966	response to topologically incorrect protein	1.079024e-2
GO:0045299	otolith mineralization	1.089393e-2
GO:0007140	male meiosis	1.093309e-2
GO:0002002	regulation of angiotensin levels in blood	1.093954e-2
GO:0048935	peripheral nervous system neuron development	1.099934e-2
GO:0072179	nephric duct formation	1.106294e-2
GO:0072164	mesonephric tubule development	1.112367e-2
GO:0048024	regulation of nuclear mRNA splicing, via spliceosome	1.116647e-2
GO:0032077	positive regulation of deoxyribonuclease activity	1.117289e-2
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	1.118092e-2
GO:0006342	chromatin silencing	1.135131e-2
GO:0046340	diacylglycerol catabolic process	1.163105e-2
GO:0046168	glycerol-3-phosphate catabolic process	1.163560e-2
GO:0033262	regulation of DNA replication involved in S phase	1.163560e-2
GO:2000594	positive regulation of metanephric DCT cell differentiation	1.166288e-2
GO:0039003	pronephric field specification	1.166288e-2
GO:0072305	negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis	1.166288e-2
GO:0043491	protein kinase B signaling cascade	1.180424e-2
GO:0071951	conversion of methionyl-tRNA to N-formyl-methionyl-tRNA	1.207163e-2
GO:0071602	phytosphingosine biosynthetic process	1.207163e-2
GO:0048859	formation of anatomical boundary	1.214946e-2
GO:0033002	muscle cell proliferation	1.215999e-2
GO:0019388	galactose catabolic process	1.219290e-2
GO:0007007	inner mitochondrial membrane organization	1.220206e-2
GO:0070671	response to interleukin-12	1.225801e-2
GO:0042135	neurotransmitter catabolic process	1.229806e-2
GO:0070286	axonemal dynein complex assembly	1.231935e-2
GO:0072205	metanephric collecting duct development	1.253281e-2
GO:0070723	response to cholesterol	1.280410e-2
GO:0002663	positive regulation of B cell tolerance induction	1.286403e-2
GO:0072215	regulation of metanephros development	1.288095e-2
GO:0018279	protein N-linked glycosylation via asparagine	1.328048e-2
GO:0009133	nucleoside diphosphate biosynthetic process	1.330592e-2
GO:0007217	tachykinin receptor signaling pathway	1.334445e-2
GO:0072181	mesonephric duct formation	1.344051e-2
GO:2001037	positive regulation of tongue muscle cell differentiation	1.344051e-2
GO:0097152	mesenchymal cell apoptosis	1.344051e-2
GO:0060821	inactivation of X chromosome by DNA methylation	1.344051e-2
GO:0060982	coronary artery morphogenesis	1.344051e-2
GO:0042335	cuticle development	1.344051e-2
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	1.344051e-2
GO:0060061	Spemann organizer formation	1.345389e-2
GO:0006498	N-terminal protein lipidation	1.345389e-2
GO:0035461	vitamin transmembrane transport	1.345389e-2
GO:0007126	meiosis	1.352425e-2
GO:0046031	ADP metabolic process	1.352943e-2
GO:0046607	positive regulation of centrosome cycle	1.365274e-2
GO:0061302	smooth muscle cell-matrix adhesion	1.365274e-2
GO:0006400	tRNA modification	1.379750e-2
GO:0051180	vitamin transport	1.384849e-2
GO:0070646	protein modification by small protein removal	1.385099e-2
GO:0010735	positive regulation of transcription via serum response element binding	1.386364e-2
GO:0033599	regulation of mammary gland epithelial cell proliferation	1.388963e-2
GO:0019058	viral infectious cycle	1.422501e-2
GO:0006544	glycine metabolic process	1.428622e-2
GO:0060347	heart trabecula formation	1.463334e-2
GO:0019255	glucose 1-phosphate metabolic process	1.482877e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0030488	tRNA methylation	5.335076e-38
GO:0006400	tRNA modification	6.436164e-32
GO:0044260	cellular macromolecule metabolic process	2.881682e-22
GO:0009451	RNA modification	1.107619e-20
GO:0090304	nucleic acid metabolic process	2.141382e-19
GO:0034470	ncRNA processing	1.319521e-18
GO:0001510	RNA methylation	1.421310e-18
GO:0034660	ncRNA metabolic process	2.128068e-17
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	1.247983e-16
GO:0006396	RNA processing	1.659437e-16
GO:0010467	gene expression	6.577564e-16
GO:0008033	tRNA processing	6.591333e-16
GO:0006399	tRNA metabolic process	1.092906e-15
GO:0006412	translation	1.549236e-15
GO:0034382	chylomicron remnant clearance	2.876281e-15
GO:0010985	negative regulation of lipoprotein particle clearance	7.416233e-15
GO:0010984	regulation of lipoprotein particle clearance	8.574394e-15
GO:0051005	negative regulation of lipoprotein lipase activity	9.531096e-14
GO:0016070	RNA metabolic process	3.919090e-13
GO:0050995	negative regulation of lipid catabolic process	1.648468e-12
GO:0006974	response to DNA damage stimulus	2.214651e-12
GO:0010987	negative regulation of high-density lipoprotein particle clearance	2.294953e-12
GO:0010897	negative regulation of triglyceride catabolic process	2.294953e-12
GO:0010982	regulation of high-density lipoprotein particle clearance	3.428691e-12
GO:0042254	ribosome biogenesis	6.205955e-12
GO:0043170	macromolecule metabolic process	2.638471e-11
GO:0048261	negative regulation of receptor-mediated endocytosis	3.919508e-11
GO:0006139	nucleobase-containing compound metabolic process	4.810559e-11
GO:0060620	regulation of cholesterol import	9.912558e-11
GO:0060192	negative regulation of lipase activity	2.013553e-10
GO:0071843	cellular component biogenesis at cellular level	2.795060e-10
GO:0045717	negative regulation of fatty acid biosynthetic process	6.845464e-10
GO:0060621	negative regulation of cholesterol import	7.024086e-10
GO:0010989	negative regulation of low-density lipoprotein particle clearance	1.047967e-9
GO:2000772	regulation of cellular senescence	1.190595e-9
GO:0022613	ribonucleoprotein complex biogenesis	1.698164e-9
GO:0032375	negative regulation of cholesterol transport	4.186409e-9
GO:0035507	regulation of myosin-light-chain-phosphatase activity	4.326046e-9
GO:0034641	cellular nitrogen compound metabolic process	4.889690e-9
GO:0006259	DNA metabolic process	5.534580e-9
GO:0050711	negative regulation of interleukin-1 secretion	6.129539e-9
GO:0045922	negative regulation of fatty acid metabolic process	1.350830e-8
GO:0071044	histone mRNA catabolic process	2.564702e-8
GO:0090234	regulation of kinetochore assembly	3.513402e-8
GO:0090169	regulation of spindle assembly	3.513402e-8
GO:0045806	negative regulation of endocytosis	3.845091e-8
GO:0043632	modification-dependent macromolecule catabolic process	3.934632e-8
GO:0050713	negative regulation of interleukin-1 beta secretion	4.703889e-8
GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	4.735794e-8
GO:0010900	negative regulation of phosphatidylcholine catabolic process	5.273944e-8
GO:0008654	phospholipid biosynthetic process	6.067479e-8
GO:0006511	ubiquitin-dependent protein catabolic process	6.680912e-8
GO:0034645	cellular macromolecule biosynthetic process	8.006493e-8
GO:0019941	modification-dependent protein catabolic process	8.365335e-8
GO:0042274	ribosomal small subunit biogenesis	8.860404e-8
GO:0016559	peroxisome fission	9.437546e-8
GO:0006346	methylation-dependent chromatin silencing	1.524456e-7
GO:0006413	translational initiation	2.508189e-7
GO:0009059	macromolecule biosynthetic process	2.797008e-7
GO:0090398	cellular senescence	2.861976e-7
GO:0045750	positive regulation of S phase of mitotic cell cycle	3.505645e-7
GO:0006364	rRNA processing	4.678471e-7
GO:0031507	heterochromatin formation	4.721117e-7
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling	5.084624e-7
GO:0034380	high-density lipoprotein particle assembly	5.313331e-7
GO:0071174	mitotic cell cycle spindle checkpoint	5.555643e-7
GO:0016072	rRNA metabolic process	6.282201e-7
GO:0008334	histone mRNA metabolic process	6.552914e-7
GO:0044265	cellular macromolecule catabolic process	7.499654e-7
GO:0006807	nitrogen compound metabolic process	8.113450e-7
GO:0046599	regulation of centriole replication	8.164620e-7
GO:0006281	DNA repair	1.013343e-6
GO:2000117	negative regulation of cysteine-type endopeptidase activity	1.093410e-6
GO:0003341	cilium movement	1.424389e-6
GO:0051973	positive regulation of telomerase activity	1.713581e-6
GO:2000381	negative regulation of mesoderm development	1.713581e-6
GO:0044237	cellular metabolic process	1.794308e-6
GO:0000075	cell cycle checkpoint	1.889548e-6
GO:0007094	mitotic cell cycle spindle assembly checkpoint	1.963370e-6
GO:0051603	proteolysis involved in cellular protein catabolic process	2.017743e-6
GO:0010172	embryonic body morphogenesis	2.098064e-6
GO:0016071	mRNA metabolic process	2.153589e-6
GO:0060696	regulation of phospholipid catabolic process	2.170663e-6
GO:0032481	positive regulation of type I interferon production	3.535839e-6
GO:0051645	Golgi localization	3.565170e-6
GO:0035461	vitamin transmembrane transport	3.727805e-6
GO:2000774	positive regulation of cellular senescence	3.876759e-6
GO:0090402	oncogene-induced senescence	3.876759e-6
GO:0035986	senescence-associated heterochromatin focus formation	3.876759e-6
GO:0046474	glycerophospholipid biosynthetic process	4.553538e-6
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	4.679033e-6
GO:0034377	plasma lipoprotein particle assembly	4.829634e-6
GO:0034447	very-low-density lipoprotein particle clearance	4.882889e-6
GO:0008380	RNA splicing	5.855260e-6
GO:0031577	spindle checkpoint	6.314339e-6
GO:0010498	proteasomal protein catabolic process	6.571645e-6
GO:0090224	regulation of spindle organization	6.713879e-6
GO:0031572	G2/M transition DNA damage checkpoint	8.274111e-6
GO:0033239	negative regulation of cellular amine metabolic process	9.072932e-6
GO:0044257	cellular protein catabolic process	9.292191e-6
GO:0019047	provirus integration	9.419793e-6
GO:0034375	high-density lipoprotein particle remodeling	1.036445e-5
GO:0071103	DNA conformation change	1.157416e-5
GO:0030163	protein catabolic process	1.267997e-5
GO:0072560	type B pancreatic cell maturation	1.321236e-5
GO:0032488	Cdc42 protein signal transduction	1.327363e-5
GO:0010824	regulation of centrosome duplication	1.327363e-5
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	1.381516e-5
GO:0045919	positive regulation of cytolysis	1.414497e-5
GO:0034381	plasma lipoprotein particle clearance	1.868392e-5
GO:0033700	phospholipid efflux	1.908295e-5
GO:0090231	regulation of spindle checkpoint	1.984171e-5
GO:0071173	spindle assembly checkpoint	1.984171e-5
GO:0090342	regulation of cell aging	2.012003e-5
GO:0010667	negative regulation of cardiac muscle cell apoptosis	2.157439e-5
GO:0001522	pseudouridine synthesis	2.157439e-5
GO:0007141	male meiosis I	2.310199e-5
GO:0009057	macromolecule catabolic process	2.401194e-5
GO:0016926	protein desumoylation	2.456946e-5
GO:0002098	tRNA wobble uridine modification	2.456946e-5
GO:0046755	non-lytic virus budding	2.792392e-5
GO:0060285	ciliary cell motility	2.962104e-5
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	2.962104e-5
GO:0090209	negative regulation of triglyceride metabolic process	3.043194e-5
GO:0090343	positive regulation of cell aging	3.318536e-5
GO:0021884	forebrain neuron development	3.400799e-5
GO:0035520	monoubiquitinated protein deubiquitination	3.543812e-5
GO:2000078	positive regulation of type B pancreatic cell development	3.676848e-5
GO:0001555	oocyte growth	3.676848e-5
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	3.676848e-5
GO:0042273	ribosomal large subunit biogenesis	4.497861e-5
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	4.564226e-5
GO:0032425	positive regulation of mismatch repair	5.205268e-5
GO:0030038	contractile actin filament bundle assembly	5.420671e-5
GO:0035912	dorsal aorta morphogenesis	5.420671e-5
GO:0031576	G2/M transition checkpoint	5.436452e-5
GO:0010665	regulation of cardiac muscle cell apoptosis	5.585012e-5
GO:0045017	glycerolipid biosynthetic process	5.783443e-5
GO:0010735	positive regulation of transcription via serum response element binding	5.881439e-5
GO:0014020	primary neural tube formation	5.902744e-5
GO:0021658	rhombomere 3 morphogenesis	6.302965e-5
GO:0021794	thalamus development	6.440723e-5
GO:0014816	satellite cell differentiation	6.929455e-5
GO:0042384	cilium assembly	7.178297e-5
GO:0034446	substrate adhesion-dependent cell spreading	7.287881e-5
GO:0006260	DNA replication	7.645723e-5
GO:2000380	regulation of mesoderm development	7.685395e-5
GO:0060384	innervation	7.685395e-5
GO:0030071	regulation of mitotic metaphase/anaphase transition	7.906915e-5
GO:0014029	neural crest formation	8.672074e-5
GO:0001843	neural tube closure	9.444517e-5
GO:0034369	plasma lipoprotein particle remodeling	9.488371e-5
GO:0032369	negative regulation of lipid transport	9.917400e-5
GO:0016567	protein ubiquitination	9.918698e-5
GO:0007049	cell cycle	1.010549e-4
GO:0070508	cholesterol import	1.047097e-4
GO:0032479	regulation of type I interferon production	1.091161e-4
GO:0002740	negative regulation of cytokine secretion involved in immune response	1.110680e-4
GO:0034227	tRNA thio-modification	1.127658e-4
GO:0071156	regulation of cell cycle arrest	1.181404e-4
GO:2001022	positive regulation of response to DNA damage stimulus	1.228012e-4
GO:0006397	mRNA processing	1.286307e-4
GO:0080164	regulation of nitric oxide metabolic process	1.299775e-4
GO:0006683	galactosylceramide catabolic process	1.299775e-4
GO:0031129	inductive cell-cell signaling	1.510416e-4
GO:0090179	planar cell polarity pathway involved in neural tube closure	1.542064e-4
GO:0033962	cytoplasmic mRNA processing body assembly	1.546141e-4
GO:0060606	tube closure	1.618643e-4
GO:0021539	subthalamus development	1.681332e-4
GO:0006686	sphingomyelin biosynthetic process	1.681519e-4
GO:0007352	zygotic specification of dorsal/ventral axis	1.715371e-4
GO:0046499	S-adenosylmethioninamine metabolic process	1.715371e-4
GO:0010564	regulation of cell cycle process	1.778424e-4
GO:0021506	anterior neuropore closure	1.782126e-4
GO:0030433	ER-associated protein catabolic process	1.884277e-4
GO:0060218	hemopoietic stem cell differentiation	1.975373e-4
GO:0070647	protein modification by small protein conjugation or removal	2.060197e-4
GO:0033554	cellular response to stress	2.094113e-4
GO:0046605	regulation of centrosome cycle	2.113479e-4
GO:0046513	ceramide biosynthetic process	2.138304e-4
GO:0035887	aortic smooth muscle cell differentiation	2.274663e-4
GO:0044267	cellular protein metabolic process	2.307829e-4
GO:0015887	pantothenate transmembrane transport	2.419204e-4
GO:0006427	histidyl-tRNA aminoacylation	2.419204e-4
GO:0015878	biotin transport	2.419204e-4
GO:0010948	negative regulation of cell cycle process	2.463818e-4
GO:0021559	trigeminal nerve development	2.659921e-4
GO:0007090	regulation of S phase of mitotic cell cycle	2.664174e-4
GO:0032203	telomere formation via telomerase	2.741593e-4
GO:0070723	response to cholesterol	2.857380e-4
GO:0006323	DNA packaging	2.903037e-4
GO:0035284	brain segmentation	2.974075e-4
GO:0007076	mitotic chromosome condensation	2.982033e-4
GO:0071281	cellular response to iron ion	3.104532e-4
GO:0032508	DNA duplex unwinding	3.179261e-4
GO:0048935	peripheral nervous system neuron development	3.437138e-4
GO:0032202	telomere assembly	3.619454e-4
GO:0006407	rRNA export from nucleus	3.619454e-4
GO:0000089	mitotic metaphase	3.619454e-4
GO:0060071	Wnt receptor signaling pathway, planar cell polarity pathway	3.645725e-4
GO:0032446	protein modification by small protein conjugation	4.130993e-4
GO:0061302	smooth muscle cell-matrix adhesion	4.244561e-4
GO:0006235	dTTP biosynthetic process	4.244561e-4
GO:0070935	3'-UTR-mediated mRNA stabilization	4.294586e-4
GO:0006420	arginyl-tRNA aminoacylation	4.294586e-4
GO:0021530	spinal cord oligodendrocyte cell fate specification	4.294586e-4
GO:0071392	cellular response to estradiol stimulus	4.459294e-4
GO:0032392	DNA geometric change	4.459294e-4
GO:0071827	plasma lipoprotein particle organization	4.676002e-4
GO:0006308	DNA catabolic process	4.916810e-4
GO:0009895	negative regulation of catabolic process	5.000847e-4
GO:0006921	cellular component disassembly involved in apoptosis	5.060314e-4
GO:0042255	ribosome assembly	5.111626e-4
GO:0071872	cellular response to epinephrine stimulus	5.244121e-4
GO:0042268	regulation of cytolysis	5.625977e-4
GO:0022007	convergent extension involved in neural plate elongation	5.625977e-4
GO:0021695	cerebellar cortex development	5.656476e-4
GO:0045739	positive regulation of DNA repair	5.821587e-4
GO:0048936	peripheral nervous system neuron axonogenesis	5.880560e-4
GO:0015739	sialic acid transport	5.880560e-4
GO:0006844	acyl carnitine transport	5.880560e-4
GO:0010725	regulation of primitive erythrocyte differentiation	5.880560e-4
GO:0051684	maintenance of Golgi location	5.943842e-4
GO:0048291	isotype switching to IgG isotypes	5.943842e-4
GO:0002368	B cell cytokine production	5.943842e-4
GO:0070170	regulation of tooth mineralization	6.286279e-4
GO:0006089	lactate metabolic process	6.286279e-4
GO:0030262	apoptotic nuclear change	6.430881e-4
GO:0021508	floor plate formation	6.489203e-4
GO:0042157	lipoprotein metabolic process	6.517154e-4
GO:0000209	protein polyubiquitination	6.597702e-4
GO:0006506	GPI anchor biosynthetic process	6.616735e-4
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	6.641996e-4
GO:0051004	regulation of lipoprotein lipase activity	6.914801e-4
GO:0006656	phosphatidylcholine biosynthetic process	7.019089e-4
GO:0006684	sphingomyelin metabolic process	7.044186e-4
GO:0097006	regulation of plasma lipoprotein particle levels	7.237486e-4
GO:0046520	sphingoid biosynthetic process	7.463927e-4
GO:0051403	stress-activated MAPK cascade	7.599801e-4
GO:0010656	negative regulation of muscle cell apoptosis	7.606699e-4
GO:0021683	cerebellar granular layer morphogenesis	7.671451e-4
GO:0006713	glucocorticoid catabolic process	7.720864e-4
GO:0032374	regulation of cholesterol transport	8.130486e-4
GO:0033344	cholesterol efflux	8.145897e-4
GO:0046498	S-adenosylhomocysteine metabolic process	8.737181e-4
GO:0006013	mannose metabolic process	8.754948e-4
GO:0048025	negative regulation of nuclear mRNA splicing, via spliceosome	8.961851e-4
GO:0006473	protein acetylation	8.997498e-4
GO:0001839	neural plate morphogenesis	9.135792e-4
GO:0006282	regulation of DNA repair	9.389075e-4
GO:0007569	cell aging	9.442905e-4
GO:0071394	cellular response to testosterone stimulus	9.505163e-4
GO:0032915	positive regulation of transforming growth factor beta2 production	9.505163e-4
GO:0021623	oculomotor nerve formation	1.022302e-3
GO:0003404	optic vesicle morphogenesis	1.022302e-3
GO:0003409	optic cup structural organization	1.022302e-3
GO:2000384	negative regulation of ectoderm development	1.028066e-3
GO:0065005	protein-lipid complex assembly	1.038464e-3
GO:0032423	regulation of mismatch repair	1.049941e-3
GO:0045833	negative regulation of lipid metabolic process	1.126909e-3
GO:0048285	organelle fission	1.149333e-3
GO:0071985	multivesicular body sorting pathway	1.162651e-3
GO:0048259	regulation of receptor-mediated endocytosis	1.176630e-3
GO:0051661	maintenance of centrosome location	1.206427e-3
GO:0035611	protein branching point deglutamylation	1.206427e-3
GO:0070370	cellular heat acclimation	1.217441e-3
GO:0060699	regulation of endoribonuclease activity	1.217441e-3
GO:0000055	ribosomal large subunit export from nucleus	1.217441e-3
GO:0000056	ribosomal small subunit export from nucleus	1.217441e-3
GO:0021603	cranial nerve formation	1.219588e-3
GO:0001672	regulation of chromatin assembly or disassembly	1.243223e-3
GO:0042304	regulation of fatty acid biosynthetic process	1.295748e-3
GO:0032057	negative regulation of translational initiation in response to stress	1.304410e-3
GO:0051972	regulation of telomerase activity	1.304859e-3
GO:0043248	proteasome assembly	1.304859e-3
GO:0007031	peroxisome organization	1.309734e-3
GO:0085020	protein K6-linked ubiquitination	1.345870e-3
GO:0070537	histone H2A K63-linked deubiquitination	1.345870e-3
GO:0051182	coenzyme transport	1.345870e-3
GO:0051865	protein autoubiquitination	1.402938e-3
GO:2000378	negative regulation of reactive oxygen species metabolic process	1.421525e-3
GO:0051726	regulation of cell cycle	1.460324e-3
GO:0035115	embryonic forelimb morphogenesis	1.527565e-3
GO:0006475	internal protein amino acid acetylation	1.549703e-3
GO:0043497	regulation of protein heterodimerization activity	1.561718e-3
GO:0035372	protein localization to microtubule	1.582596e-3
GO:0014034	neural crest cell fate commitment	1.582596e-3
GO:0043252	sodium-independent organic anion transport	1.631456e-3
GO:0000027	ribosomal large subunit assembly	1.631456e-3
GO:0002561	basophil degranulation	1.631456e-3
GO:0071034	CUT catabolic process	1.727973e-3
GO:0032774	RNA biosynthetic process	1.746200e-3
GO:0034063	stress granule assembly	1.760195e-3
GO:0043543	protein acylation	1.781376e-3
GO:0046479	glycosphingolipid catabolic process	1.830809e-3
GO:0006297	nucleotide-excision repair, DNA gap filling	1.865405e-3
GO:0050994	regulation of lipid catabolic process	1.914240e-3
GO:0046519	sphingoid metabolic process	1.954889e-3
GO:0010424	DNA methylation on cytosine within a CG sequence	1.994018e-3
GO:0006351	transcription, DNA-dependent	2.023188e-3
GO:0008208	C21-steroid hormone catabolic process	2.077099e-3
GO:0071544	diphosphoinositol polyphosphate catabolic process	2.077099e-3
GO:0010896	regulation of triglyceride catabolic process	2.107309e-3
GO:0030149	sphingolipid catabolic process	2.137392e-3
GO:0000460	maturation of 5.8S rRNA	2.139389e-3
GO:0051775	response to redox state	2.200674e-3
GO:0002679	respiratory burst involved in defense response	2.255040e-3
GO:0031122	cytoplasmic microtubule organization	2.391395e-3
GO:2000383	regulation of ectoderm development	2.451130e-3
GO:0000087	M phase of mitotic cell cycle	2.463940e-3
GO:0051055	negative regulation of lipid biosynthetic process	2.471847e-3
GO:0046963	3'-phosphoadenosine 5'-phosphosulfate transport	2.485439e-3
GO:0061034	olfactory bulb mitral cell layer development	2.488259e-3
GO:0006513	protein monoubiquitination	2.527411e-3
GO:0033505	floor plate morphogenesis	2.563871e-3
GO:0021707	cerebellar granule cell differentiation	2.597749e-3
GO:0006268	DNA unwinding involved in replication	2.597749e-3
GO:0008211	glucocorticoid metabolic process	2.599533e-3
GO:0045814	negative regulation of gene expression, epigenetic	2.656661e-3
GO:0045648	positive regulation of erythrocyte differentiation	2.771153e-3
GO:0070172	positive regulation of tooth mineralization	2.841959e-3
GO:0021549	cerebellum development	2.852628e-3
GO:0006342	chromatin silencing	2.873017e-3
GO:0006672	ceramide metabolic process	2.888359e-3
GO:0021681	cerebellar granular layer development	2.980605e-3
GO:0044238	primary metabolic process	3.057020e-3
GO:0035092	sperm chromatin condensation	3.076914e-3
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	3.119032e-3
GO:0034421	post-translational protein acetylation	3.150753e-3
GO:0003151	outflow tract morphogenesis	3.177140e-3
GO:0006261	DNA-dependent DNA replication	3.354717e-3
GO:0044249	cellular biosynthetic process	3.375993e-3
GO:0033561	regulation of water loss via skin	3.421174e-3
GO:0006366	transcription from RNA polymerase II promoter	3.443592e-3
GO:0002536	respiratory burst involved in inflammatory response	3.474334e-3
GO:0042697	menopause	3.474334e-3
GO:0071028	nuclear mRNA surveillance	3.484169e-3
GO:0045575	basophil activation	3.484169e-3
GO:0035750	protein localization to myelin sheath abaxonal region	3.484169e-3
GO:0021846	cell proliferation in forebrain	3.514750e-3
GO:2000036	regulation of stem cell maintenance	3.583947e-3
GO:0071934	thiamine transmembrane transport	3.680856e-3
GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	3.680856e-3
GO:0035621	ER to Golgi ceramide transport	3.680856e-3
GO:0031570	DNA integrity checkpoint	3.741844e-3
GO:0048298	positive regulation of isotype switching to IgA isotypes	3.772364e-3
GO:0000281	cytokinesis after mitosis	3.772364e-3
GO:0060932	His-Purkinje system cell differentiation	3.812833e-3
GO:0060926	pacemaker cell development	3.812833e-3
GO:0021569	rhombomere 3 development	3.843039e-3
GO:0001732	formation of translation initiation complex	4.053755e-3
GO:0032055	negative regulation of translation in response to stress	4.053755e-3
GO:0070936	protein K48-linked ubiquitination	4.115751e-3
GO:0031497	chromatin assembly	4.118247e-3
GO:0000077	DNA damage checkpoint	4.127542e-3
GO:0007059	chromosome segregation	4.135515e-3
GO:0060911	cardiac cell fate commitment	4.206993e-3
GO:0045666	positive regulation of neuron differentiation	4.409066e-3
GO:0048668	collateral sprouting	4.422845e-3
GO:0016075	rRNA catabolic process	4.422845e-3
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.422845e-3
GO:0042481	regulation of odontogenesis	4.479594e-3
GO:0016482	cytoplasmic transport	4.479832e-3
GO:0030505	inorganic diphosphate transport	4.484778e-3
GO:0000028	ribosomal small subunit assembly	4.513213e-3
GO:0006782	protoporphyrinogen IX biosynthetic process	4.589318e-3
GO:0043488	regulation of mRNA stability	4.612130e-3
GO:0070979	protein K11-linked ubiquitination	4.644814e-3
GO:0045646	regulation of erythrocyte differentiation	4.650282e-3
GO:0046881	positive regulation of follicle-stimulating hormone secretion	4.736243e-3
GO:0021758	putamen development	4.736243e-3
GO:0071474	cellular hyperosmotic response	4.736243e-3
GO:0021660	rhombomere 3 formation	4.736243e-3
GO:0021666	rhombomere 5 formation	4.736243e-3
GO:0021757	caudate nucleus development	4.736243e-3
GO:0033261	regulation of S phase	4.844612e-3
GO:0006505	GPI anchor metabolic process	5.178865e-3
GO:0023021	termination of signal transduction	5.437219e-3
GO:0010724	regulation of definitive erythrocyte differentiation	5.437219e-3
GO:0007067	mitosis	5.547899e-3
GO:0022037	metencephalon development	5.686928e-3
GO:0001982	baroreceptor response to decreased systemic arterial blood pressure	5.758548e-3
GO:0010825	positive regulation of centrosome duplication	5.758548e-3
GO:0000917	barrier septum formation	5.758548e-3
GO:0034661	ncRNA catabolic process	5.911129e-3
GO:0042733	embryonic digit morphogenesis	5.936481e-3
GO:0007220	Notch receptor processing	6.193802e-3
GO:0046600	negative regulation of centriole replication	6.314332e-3
GO:0034441	plasma lipoprotein particle oxidation	6.314332e-3
GO:0001881	receptor recycling	6.314332e-3
GO:0009992	cellular water homeostasis	6.314332e-3
GO:2000050	regulation of non-canonical Wnt receptor signaling pathway	6.371832e-3
GO:0007635	chemosensory behavior	6.371832e-3
GO:0006258	UDP-glucose catabolic process	6.380282e-3
GO:0031119	tRNA pseudouridine synthesis	6.380282e-3
GO:0070086	ubiquitin-dependent endocytosis	6.380282e-3
GO:0010835	regulation of protein ADP-ribosylation	6.380282e-3
GO:0046514	ceramide catabolic process	6.400802e-3
GO:0006481	C-terminal protein methylation	6.458409e-3
GO:0000415	negative regulation of histone H3-K36 methylation	6.458409e-3
GO:0046477	glycosylceramide catabolic process	6.624530e-3
GO:0060059	embryonic retina morphogenesis in camera-type eye	6.658141e-3
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	6.813345e-3
GO:0050709	negative regulation of protein secretion	6.880784e-3
GO:0006661	phosphatidylinositol biosynthetic process	7.056720e-3
GO:0051181	cofactor transport	7.362586e-3
GO:0071870	cellular response to catecholamine stimulus	7.653614e-3
GO:0060931	sinoatrial node cell development	7.893842e-3
GO:0032876	negative regulation of DNA endoreduplication	7.893842e-3
GO:0003167	atrioventricular bundle cell differentiation	7.893842e-3
GO:0032776	DNA methylation on cytosine	7.893842e-3
GO:0043687	post-translational protein modification	7.908736e-3
GO:0035136	forelimb morphogenesis	7.951235e-3
GO:0030168	platelet activation	7.967985e-3
GO:0021675	nerve development	8.059660e-3
GO:0090074	negative regulation of protein homodimerization activity	8.252580e-3
GO:0000414	regulation of histone H3-K36 methylation	8.252580e-3
GO:0001954	positive regulation of cell-matrix adhesion	8.378406e-3
GO:0043487	regulation of RNA stability	8.503212e-3
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	8.520461e-3
GO:0006695	cholesterol biosynthetic process	8.625253e-3
GO:0043206	fibril organization	8.667150e-3
GO:0048532	anatomical structure arrangement	8.777364e-3
GO:0033490	cholesterol biosynthetic process via lathosterol	8.823627e-3
GO:0006011	UDP-glucose metabolic process	8.823627e-3
GO:0022601	menstrual cycle phase	8.898723e-3
GO:0010159	specification of organ position	9.020073e-3
GO:0001840	neural plate development	9.039015e-3
GO:0000278	mitotic cell cycle	9.121553e-3
GO:0035886	vascular smooth muscle cell differentiation	9.133192e-3
GO:0007418	ventral midline development	9.219921e-3
GO:0030953	astral microtubule organization	9.331990e-3
GO:0010660	regulation of muscle cell apoptosis	9.355293e-3
GO:0006302	double-strand break repair	9.503108e-3
GO:0032859	activation of Ral GTPase activity	9.592440e-3
GO:0044340	canonical Wnt receptor signaling pathway involved in regulation of cell proliferation	9.601608e-3
GO:2000053	regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	9.712103e-3
GO:0006270	DNA-dependent DNA replication initiation	9.712103e-3
GO:0060920	pacemaker cell differentiation	9.712103e-3
GO:0051301	cell division	9.937833e-3
GO:0046434	organophosphate catabolic process	1.007673e-2
GO:0046466	membrane lipid catabolic process	1.007755e-2
GO:0060580	ventral spinal cord interneuron fate determination	1.030800e-2
GO:0048550	negative regulation of pinocytosis	1.030800e-2
GO:0090182	regulation of secretion of lysosomal enzymes	1.030800e-2
GO:0090186	regulation of pancreatic juice secretion	1.030800e-2
GO:0071048	nuclear retention of unspliced pre-mRNA at the site of transcription	1.030800e-2
GO:0071035	nuclear polyadenylation-dependent rRNA catabolic process	1.030800e-2
GO:0048239	negative regulation of DNA recombination at telomere	1.030800e-2
GO:0001971	negative regulation of activation of membrane attack complex	1.030800e-2
GO:0006430	lysyl-tRNA aminoacylation	1.030800e-2
GO:0003327	type B pancreatic cell fate commitment	1.030800e-2
GO:0018125	peptidyl-cysteine methylation	1.030800e-2
GO:0031629	synaptic vesicle fusion to presynaptic membrane	1.030800e-2
GO:0071025	RNA surveillance	1.051937e-2
GO:0001787	natural killer cell proliferation	1.051937e-2
GO:0015876	acetyl-CoA transport	1.051937e-2
GO:0034101	erythrocyte homeostasis	1.053093e-2
GO:0010991	negative regulation of SMAD protein complex assembly	1.059499e-2
GO:0070842	aggresome assembly	1.059499e-2
GO:0010225	response to UV-C	1.099427e-2
GO:2001020	regulation of response to DNA damage stimulus	1.104835e-2
GO:0030031	cell projection assembly	1.110028e-2
GO:0034763	negative regulation of transmembrane transport	1.113088e-2
GO:0003166	bundle of His development	1.117443e-2
GO:0090187	positive regulation of pancreatic juice secretion	1.140241e-2
GO:0090340	positive regulation of secretion of lysosomal enzymes	1.140241e-2
GO:0090108	positive regulation of high-density lipoprotein particle assembly	1.140241e-2
GO:0010836	negative regulation of protein ADP-ribosylation	1.140241e-2
GO:0007113	endomitotic cell cycle	1.140241e-2
GO:0043461	proton-transporting ATP synthase complex assembly	1.141856e-2
GO:0000279	M phase	1.151438e-2
GO:0061384	heart trabecular morphogenesis	1.158369e-2
GO:0072040	negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis	1.161431e-2
GO:0045039	protein import into mitochondrial inner membrane	1.161431e-2
GO:0021783	preganglionic parasympathetic nervous system development	1.169859e-2
GO:0072537	fibroblast activation	1.174894e-2
GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport	1.174894e-2
GO:0002432	granuloma formation	1.174894e-2
GO:0010046	response to mycotoxin	1.174894e-2
GO:0006424	glutamyl-tRNA aminoacylation	1.174894e-2
GO:0006422	aspartyl-tRNA aminoacylation	1.174894e-2
GO:0031330	negative regulation of cellular catabolic process	1.182354e-2
GO:2000104	negative regulation of DNA-dependent DNA replication	1.201068e-2
GO:0006354	transcription elongation, DNA-dependent	1.212345e-2
GO:0032692	negative regulation of interleukin-1 production	1.213094e-2
GO:0060806	negative regulation of cell differentiation involved in embryonic placenta development	1.213421e-2
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	1.213421e-2
GO:0031061	negative regulation of histone methylation	1.227483e-2
GO:0071826	ribonucleoprotein complex subunit organization	1.262854e-2
GO:0021557	oculomotor nerve development	1.277806e-2
GO:0007525	somatic muscle development	1.277806e-2
GO:0071470	cellular response to osmotic stress	1.280511e-2
GO:0031573	intra-S DNA damage checkpoint	1.280511e-2
GO:0021696	cerebellar cortex morphogenesis	1.293462e-2
GO:0070536	protein K63-linked deubiquitination	1.311341e-2
GO:0018393	internal peptidyl-lysine acetylation	1.331064e-2
GO:0008215	spermine metabolic process	1.338481e-2
GO:0060347	heart trabecula formation	1.350826e-2
GO:0032728	positive regulation of interferon-beta production	1.383752e-2