Novel motif:163

name:	motif163_GARTCGCCCTGTNA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0010883	regulation of lipid storage	2.098496e-18
GO:0010888	negative regulation of lipid storage	8.598906e-14
GO:0001300	chronological cell aging	2.511071e-13
GO:0010743	regulation of macrophage derived foam cell differentiation	7.182626e-12
GO:0010745	negative regulation of macrophage derived foam cell differentiation	1.427112e-10
GO:2000097	regulation of smooth muscle cell-matrix adhesion	1.257205e-9
GO:0046325	negative regulation of glucose import	3.511839e-9
GO:0045768	positive regulation of anti-apoptosis	5.755490e-9
GO:0070417	cellular response to cold	7.853407e-9
GO:0061043	regulation of vascular wound healing	9.080002e-9
GO:0035588	G-protein coupled purinergic receptor signaling pathway	1.365550e-8
GO:0061028	establishment of endothelial barrier	1.688381e-8
GO:2000098	negative regulation of smooth muscle cell-matrix adhesion	2.156336e-8
GO:0071258	cellular response to gravity	2.156336e-8
GO:0061044	negative regulation of vascular wound healing	2.156336e-8
GO:0035491	positive regulation of leukotriene production involved in inflammatory response	2.156336e-8
GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway	3.255764e-8
GO:0031663	lipopolysaccharide-mediated signaling pathway	3.357470e-8
GO:0070059	apoptosis in response to endoplasmic reticulum stress	4.893041e-8
GO:0071222	cellular response to lipopolysaccharide	5.900277e-8
GO:0045767	regulation of anti-apoptosis	1.035842e-7
GO:0071219	cellular response to molecule of bacterial origin	1.050145e-7
GO:0035587	purinergic receptor signaling pathway	1.159670e-7
GO:0009220	pyrimidine ribonucleotide biosynthetic process	2.007621e-7
GO:0010466	negative regulation of peptidase activity	2.920921e-7
GO:0032495	response to muramyl dipeptide	2.950545e-7
GO:0010884	positive regulation of lipid storage	3.355404e-7
GO:0060401	cytosolic calcium ion transport	3.708470e-7
GO:0009218	pyrimidine ribonucleotide metabolic process	3.991630e-7
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	4.152494e-7
GO:0071216	cellular response to biotic stimulus	8.240227e-7
GO:0032769	negative regulation of monooxygenase activity	8.367996e-7
GO:0032496	response to lipopolysaccharide	1.051001e-6
GO:0006767	water-soluble vitamin metabolic process	1.086466e-6
GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	1.113591e-6
GO:0006222	UMP biosynthetic process	1.115052e-6
GO:0050852	T cell receptor signaling pathway	1.139699e-6
GO:0052547	regulation of peptidase activity	1.179395e-6
GO:0048791	calcium ion-dependent exocytosis of neurotransmitter	1.676836e-6
GO:0006916	anti-apoptosis	1.756098e-6
GO:0032494	response to peptidoglycan	1.804153e-6
GO:0046131	pyrimidine ribonucleoside metabolic process	1.822863e-6
GO:0048685	negative regulation of collateral sprouting of intact axon in response to injury	1.889898e-6
GO:0033629	negative regulation of cell adhesion mediated by integrin	1.924331e-6
GO:0009129	pyrimidine nucleoside monophosphate metabolic process	1.979539e-6
GO:0009116	nucleoside metabolic process	2.460488e-6
GO:0060296	regulation of cilium beat frequency involved in ciliary motility	2.482518e-6
GO:0050748	negative regulation of lipoprotein metabolic process	2.772920e-6
GO:0051707	response to other organism	2.946473e-6
GO:0042246	tissue regeneration	3.005885e-6
GO:0060027	convergent extension involved in gastrulation	3.197752e-6
GO:0050775	positive regulation of dendrite morphogenesis	3.265954e-6
GO:0051354	negative regulation of oxidoreductase activity	3.690916e-6
GO:0060928	atrioventricular node cell development	3.768840e-6
GO:0060929	atrioventricular node cell fate commitment	3.768840e-6
GO:0003342	proepicardium development	3.768840e-6
GO:0003168	cardiac Purkinje fiber cell differentiation	3.768840e-6
GO:0051904	pigment granule transport	3.951809e-6
GO:0032402	melanosome transport	4.097848e-6
GO:0006359	regulation of transcription from RNA polymerase III promoter	4.107273e-6
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	4.155254e-6
GO:0007605	sensory perception of sound	4.568052e-6
GO:0002237	response to molecule of bacterial origin	4.905917e-6
GO:0022002	negative regulation of anterior neural cell fate commitment of the neural plate by Wnt receptor signaling pathway	4.963322e-6
GO:0048263	determination of dorsal identity	4.963322e-6
GO:0055014	atrial cardiac muscle cell development	5.165691e-6
GO:0007286	spermatid development	6.046848e-6
GO:0031953	negative regulation of protein autophosphorylation	6.558535e-6
GO:0009607	response to biotic stimulus	6.631349e-6
GO:0051384	response to glucocorticoid stimulus	6.732722e-6
GO:0009615	response to virus	7.011873e-6
GO:0006213	pyrimidine nucleoside metabolic process	7.179464e-6
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	7.405071e-6
GO:0055093	response to hyperoxia	7.665710e-6
GO:0043900	regulation of multi-organism process	8.507733e-6
GO:0051877	pigment granule aggregation in cell center	8.703200e-6
GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway	9.804932e-6
GO:0002429	immune response-activating cell surface receptor signaling pathway	9.928493e-6
GO:0042424	catecholamine catabolic process	1.026668e-5
GO:0003222	ventricular trabecular myocardium morphogenesis	1.065275e-5
GO:0006221	pyrimidine nucleotide biosynthetic process	1.065495e-5
GO:0051346	negative regulation of hydrolase activity	1.140031e-5
GO:0010038	response to metal ion	1.218568e-5
GO:0048515	spermatid differentiation	1.319561e-5
GO:0060402	calcium ion transport into cytosol	1.370798e-5
GO:0050851	antigen receptor-mediated signaling pathway	1.383245e-5
GO:0031960	response to corticosteroid stimulus	1.687377e-5
GO:0060556	regulation of vitamin D biosynthetic process	1.721844e-5
GO:0070874	negative regulation of glycogen metabolic process	1.742934e-5
GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus	1.750953e-5
GO:0051385	response to mineralocorticoid stimulus	1.771154e-5
GO:0033619	membrane protein proteolysis	1.855285e-5
GO:0051875	pigment granule localization	1.858915e-5
GO:0032102	negative regulation of response to external stimulus	1.865440e-5
GO:0050954	sensory perception of mechanical stimulus	1.925899e-5
GO:0016576	histone dephosphorylation	1.980267e-5
GO:0030538	embryonic genitalia morphogenesis	2.078673e-5
GO:0010886	positive regulation of cholesterol storage	2.115921e-5
GO:0032400	melanosome localization	2.124086e-5
GO:0060632	regulation of microtubule-based movement	2.167951e-5
GO:0001885	endothelial cell development	2.191261e-5
GO:0046847	filopodium assembly	2.230851e-5
GO:0061041	regulation of wound healing	2.313270e-5
GO:0006554	lysine catabolic process	2.377902e-5
GO:0002768	immune response-regulating cell surface receptor signaling pathway	2.416749e-5
GO:0060920	pacemaker cell differentiation	2.428866e-5
GO:0060971	embryonic heart tube left/right pattern formation	2.428866e-5
GO:0043973	histone H3-K4 acetylation	2.452503e-5
GO:0046985	positive regulation of hemoglobin biosynthetic process	2.452503e-5
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	2.452503e-5
GO:0007181	transforming growth factor beta receptor complex assembly	2.555308e-5
GO:0030035	microspike assembly	2.577704e-5
GO:0021756	striatum development	3.061410e-5
GO:0051282	regulation of sequestering of calcium ion	3.090416e-5
GO:0031284	positive regulation of guanylate cyclase activity	3.119611e-5
GO:0071674	mononuclear cell migration	3.119611e-5
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB cascade	3.137579e-5
GO:0051905	establishment of pigment granule localization	3.165640e-5
GO:0003278	apoptosis involved in heart morphogenesis	3.224443e-5
GO:0009726	detection of endogenous stimulus	3.228971e-5
GO:0050685	positive regulation of mRNA processing	3.411958e-5
GO:0032401	establishment of melanosome localization	3.556863e-5
GO:0045719	negative regulation of glycogen biosynthetic process	3.671494e-5
GO:0019413	acetate biosynthetic process	3.745469e-5
GO:0019542	propionate biosynthetic process	3.745469e-5
GO:0002882	positive regulation of chronic inflammatory response to non-antigenic stimulus	4.054352e-5
GO:0051209	release of sequestered calcium ion into cytosol	4.078494e-5
GO:0021881	Wnt receptor signaling pathway involved in forebrain neuron fate commitment	4.107673e-5
GO:0030031	cell projection assembly	4.226315e-5
GO:0002253	activation of immune response	4.347704e-5
GO:0044205	'de novo' UMP biosynthetic process	4.435126e-5
GO:0051900	regulation of mitochondrial depolarization	4.578128e-5
GO:0035058	nonmotile primary cilium assembly	4.585777e-5
GO:0033239	negative regulation of cellular amine metabolic process	4.628974e-5
GO:0009629	response to gravity	4.640704e-5
GO:0061014	positive regulation of mRNA catabolic process	4.732438e-5
GO:0035590	purinergic nucleotide receptor signaling pathway	4.761951e-5
GO:0051591	response to cAMP	4.787222e-5
GO:0010713	negative regulation of collagen metabolic process	5.022733e-5
GO:0046951	ketone body biosynthetic process	5.407258e-5
GO:0010829	negative regulation of glucose transport	5.625697e-5
GO:0009617	response to bacterium	5.792991e-5
GO:0034140	negative regulation of toll-like receptor 3 signaling pathway	5.866910e-5
GO:0051656	establishment of organelle localization	6.357665e-5
GO:0003127	detection of nodal flow	6.762400e-5
GO:0009855	determination of bilateral symmetry	7.320006e-5
GO:0042976	activation of Janus kinase activity	7.607692e-5
GO:0032049	cardiolipin biosynthetic process	7.630849e-5
GO:0010044	response to aluminum ion	7.747820e-5
GO:0010033	response to organic substance	7.753848e-5
GO:0043627	response to estrogen stimulus	8.130414e-5
GO:0090308	regulation of methylation-dependent chromatin silencing	8.738021e-5
GO:0051704	multi-organism process	8.766203e-5
GO:0051258	protein polymerization	8.851154e-5
GO:0009124	nucleoside monophosphate biosynthetic process	8.874556e-5
GO:0006509	membrane protein ectodomain proteolysis	9.241391e-5
GO:0006540	glutamate decarboxylation to succinate	9.561161e-5
GO:0030970	retrograde protein transport, ER to cytosol	9.740168e-5
GO:0032374	regulation of cholesterol transport	1.011994e-4
GO:0007253	cytoplasmic sequestering of NF-kappaB	1.017324e-4
GO:0010288	response to lead ion	1.070319e-4
GO:0043086	negative regulation of catalytic activity	1.072614e-4
GO:0022009	central nervous system vasculogenesis	1.106447e-4
GO:0051902	negative regulation of mitochondrial depolarization	1.120902e-4
GO:0070483	detection of hypoxia	1.181249e-4
GO:0060585	positive regulation of prostaglandin-endoperoxide synthase activity	1.192031e-4
GO:0033059	cellular pigmentation	1.194878e-4
GO:0031442	positive regulation of mRNA 3'-end processing	1.202429e-4
GO:0050688	regulation of defense response to virus	1.227085e-4
GO:0046950	cellular ketone body metabolic process	1.269914e-4
GO:0021544	subpallium development	1.270540e-4
GO:0009799	specification of symmetry	1.294295e-4
GO:0032369	negative regulation of lipid transport	1.417802e-4
GO:0048262	determination of dorsal/ventral asymmetry	1.419049e-4
GO:0032606	type I interferon production	1.477292e-4
GO:0032088	negative regulation of NF-kappaB transcription factor activity	1.484894e-4
GO:0010875	positive regulation of cholesterol efflux	1.488177e-4
GO:0003254	regulation of membrane depolarization	1.488177e-4
GO:0001101	response to acid	1.595222e-4
GO:0071625	vocalization behavior	1.615059e-4
GO:0034135	regulation of toll-like receptor 2 signaling pathway	1.621789e-4
GO:0072528	pyrimidine-containing compound biosynthetic process	1.664611e-4
GO:0009296	flagellum assembly	1.694996e-4
GO:0032692	negative regulation of interleukin-1 production	1.788635e-4
GO:0042136	neurotransmitter biosynthetic process	1.816103e-4
GO:0048545	response to steroid hormone stimulus	1.831423e-4
GO:0009719	response to endogenous stimulus	1.833502e-4
GO:0045760	positive regulation of action potential	1.857716e-4
GO:0051568	histone H3-K4 methylation	1.896206e-4
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	1.938918e-4
GO:0042221	response to chemical stimulus	1.973528e-4
GO:0032368	regulation of lipid transport	1.977417e-4
GO:0051131	chaperone-mediated protein complex assembly	1.998598e-4
GO:0006959	humoral immune response	2.046941e-4
GO:0002831	regulation of response to biotic stimulus	2.055095e-4
GO:0016339	calcium-dependent cell-cell adhesion	2.142857e-4
GO:0050668	positive regulation of homocysteine metabolic process	2.300467e-4
GO:0045963	negative regulation of dopamine metabolic process	2.300467e-4
GO:0016311	dephosphorylation	2.349384e-4
GO:0009119	ribonucleoside metabolic process	2.421074e-4
GO:0006517	protein deglycosylation	2.421998e-4
GO:0042981	regulation of apoptosis	2.457336e-4
GO:0009123	nucleoside monophosphate metabolic process	2.457623e-4
GO:0045909	positive regulation of vasodilation	2.493960e-4
GO:0014853	regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction	2.559925e-4
GO:0040007	growth	2.571881e-4
GO:0051001	negative regulation of nitric-oxide synthase activity	2.577602e-4
GO:0010885	regulation of cholesterol storage	2.633474e-4
GO:0033240	positive regulation of cellular amine metabolic process	2.644979e-4
GO:0061003	positive regulation of dendritic spine morphogenesis	2.700791e-4
GO:0002861	regulation of inflammatory response to antigenic stimulus	2.738397e-4
GO:0042133	neurotransmitter metabolic process	2.770749e-4
GO:0051797	regulation of hair follicle development	2.806258e-4
GO:0046952	ketone body catabolic process	2.894220e-4
GO:0015755	fructose transport	2.967371e-4
GO:0014826	vein smooth muscle contraction	2.985042e-4
GO:0006940	regulation of smooth muscle contraction	3.049870e-4
GO:0014909	smooth muscle cell migration	3.068603e-4
GO:0016081	synaptic vesicle docking involved in exocytosis	3.081957e-4
GO:0048260	positive regulation of receptor-mediated endocytosis	3.083761e-4
GO:0032376	positive regulation of cholesterol transport	3.115736e-4
GO:0060841	venous blood vessel development	3.128621e-4
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	3.162291e-4
GO:0002536	respiratory burst involved in inflammatory response	3.234656e-4
GO:0051176	positive regulation of sulfur metabolic process	3.281699e-4
GO:0060972	left/right pattern formation	3.335240e-4
GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity	3.335278e-4
GO:0048518	positive regulation of biological process	3.336154e-4
GO:0060923	cardiac muscle cell fate commitment	3.412695e-4
GO:0052548	regulation of endopeptidase activity	3.490476e-4
GO:0046324	regulation of glucose import	3.572550e-4
GO:0022617	extracellular matrix disassembly	3.603427e-4
GO:0018352	protein-pyridoxal-5-phosphate linkage	3.606804e-4
GO:0009068	aspartate family amino acid catabolic process	3.773917e-4
GO:0035507	regulation of myosin-light-chain-phosphatase activity	3.875610e-4
GO:0043375	CD8-positive, alpha-beta T cell lineage commitment	3.875610e-4
GO:0032848	negative regulation of cellular pH reduction	3.875610e-4
GO:0021747	cochlear nucleus development	3.875610e-4
GO:0010447	response to acidity	3.875610e-4
GO:0014042	positive regulation of neuron maturation	3.875610e-4
GO:0030212	hyaluronan metabolic process	3.918738e-4
GO:0002678	positive regulation of chronic inflammatory response	3.918738e-4
GO:0043067	regulation of programmed cell death	3.937409e-4
GO:0051051	negative regulation of transport	3.988294e-4
GO:0032691	negative regulation of interleukin-1 beta production	3.998650e-4
GO:0021570	rhombomere 4 development	4.004361e-4
GO:0006542	glutamine biosynthetic process	4.156540e-4
GO:0021546	rhombomere development	4.241878e-4
GO:0042762	regulation of sulfur metabolic process	4.327879e-4
GO:0003058	hormonal regulation of the force of heart contraction	4.351900e-4
GO:0060311	negative regulation of elastin catabolic process	4.429928e-4
GO:0010711	negative regulation of collagen catabolic process	4.429928e-4
GO:0060313	negative regulation of blood vessel remodeling	4.429928e-4
GO:0010703	negative regulation of histolysis	4.429928e-4
GO:0002765	immune response-inhibiting signal transduction	4.429928e-4
GO:0002826	negative regulation of T-helper 1 type immune response	4.438450e-4
GO:0007569	cell aging	4.452423e-4
GO:0042634	regulation of hair cycle	4.626359e-4
GO:0015993	molecular hydrogen transport	4.626851e-4
GO:0009156	ribonucleoside monophosphate biosynthetic process	4.650036e-4
GO:0090310	negative regulation of methylation-dependent chromatin silencing	4.676723e-4
GO:0010889	regulation of sequestering of triglyceride	4.693691e-4
GO:0061013	regulation of mRNA catabolic process	4.810140e-4
GO:0035635	entry of bacterium into host cell	4.977400e-4
GO:0052066	entry of symbiont into host cell by promotion of host phagocytosis	4.977400e-4
GO:0046984	regulation of hemoglobin biosynthetic process	4.977400e-4
GO:0003100	regulation of systemic arterial blood pressure by endothelin	5.025958e-4
GO:0097117	guanylate kinase-associated protein clustering	5.066742e-4
GO:0097114	N-methyl-D-aspartate receptor clustering	5.066742e-4
GO:0048683	regulation of collateral sprouting of intact axon in response to injury	5.066742e-4
GO:0097112	gamma-aminobutyric acid receptor clustering	5.066742e-4
GO:0050778	positive regulation of immune response	5.068181e-4
GO:0045471	response to ethanol	5.163649e-4
GO:0014824	artery smooth muscle contraction	5.172201e-4
GO:0010735	positive regulation of transcription via serum response element binding	5.214836e-4
GO:0000060	protein import into nucleus, translocation	5.310904e-4
GO:0043623	cellular protein complex assembly	5.392214e-4
GO:0030195	negative regulation of blood coagulation	5.407632e-4
GO:0042985	negative regulation of amyloid precursor protein biosynthetic process	5.437739e-4
GO:0030643	cellular phosphate ion homeostasis	5.701675e-4
GO:0045638	negative regulation of myeloid cell differentiation	5.870190e-4
GO:0007157	heterophilic cell-cell adhesion	5.875366e-4
GO:0050666	regulation of homocysteine metabolic process	5.929838e-4
GO:0001808	negative regulation of type IV hypersensitivity	5.929838e-4
GO:0002684	positive regulation of immune system process	5.994495e-4
GO:0048012	hepatocyte growth factor receptor signaling pathway	6.069889e-4
GO:0070350	regulation of white fat cell proliferation	6.181490e-4
GO:0032101	regulation of response to external stimulus	6.278796e-4
GO:0070278	extracellular matrix constituent secretion	6.295822e-4
GO:0010260	organ senescence	6.295822e-4
GO:0051094	positive regulation of developmental process	6.389747e-4
GO:0051412	response to corticosterone stimulus	6.471627e-4
GO:0006808	regulation of nitrogen utilization	6.542555e-4
GO:0009310	amine catabolic process	6.557545e-4
GO:0008228	opsonization	6.573862e-4
GO:0007214	gamma-aminobutyric acid signaling pathway	6.573862e-4
GO:0048566	embryonic digestive tract development	6.576999e-4
GO:0002690	positive regulation of leukocyte chemotaxis	6.608628e-4
GO:0045930	negative regulation of mitotic cell cycle	7.011579e-4
GO:0001973	adenosine receptor signaling pathway	7.209335e-4
GO:0031282	regulation of guanylate cyclase activity	7.259837e-4
GO:0032355	response to estradiol stimulus	7.278008e-4
GO:0051956	negative regulation of amino acid transport	7.284720e-4
GO:0034139	regulation of toll-like receptor 3 signaling pathway	7.502455e-4
GO:0061048	negative regulation of branching involved in lung morphogenesis	7.599550e-4
GO:0033688	regulation of osteoblast proliferation	7.690585e-4
GO:0008653	lipopolysaccharide metabolic process	7.690585e-4
GO:0090023	positive regulation of neutrophil chemotaxis	7.734591e-4
GO:0001807	regulation of type IV hypersensitivity	7.780397e-4
GO:0007584	response to nutrient	7.823904e-4
GO:0006888	ER to Golgi vesicle-mediated transport	8.056264e-4
GO:0032753	positive regulation of interleukin-4 production	8.140400e-4
GO:0009725	response to hormone stimulus	8.211389e-4
GO:0043064	flagellum organization	8.227811e-4
GO:0030505	inorganic diphosphate transport	8.240012e-4
GO:0000187	activation of MAPK activity	8.256005e-4
GO:0045083	negative regulation of interleukin-12 biosynthetic process	8.351760e-4
GO:0070904	transepithelial L-ascorbic acid transport	8.351760e-4
GO:0043570	maintenance of DNA repeat elements	8.584871e-4
GO:0002064	epithelial cell development	8.597332e-4
GO:0007174	epidermal growth factor catabolic process	8.643611e-4
GO:0007207	activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway	8.677210e-4
GO:0009888	tissue development	8.757297e-4
GO:0048536	spleen development	8.844483e-4
GO:0044092	negative regulation of molecular function	8.864460e-4
GO:0050746	regulation of lipoprotein metabolic process	8.938594e-4
GO:0010744	positive regulation of macrophage derived foam cell differentiation	9.012912e-4
GO:0014912	negative regulation of smooth muscle cell migration	9.013214e-4
GO:0051953	negative regulation of amine transport	9.038327e-4
GO:0034371	chylomicron remodeling	9.256156e-4
GO:0042730	fibrinolysis	9.461334e-4
GO:0002326	B cell lineage commitment	9.490854e-4
GO:0045823	positive regulation of heart contraction	9.751012e-4
GO:0010243	response to organic nitrogen	9.913080e-4
GO:0042994	cytoplasmic sequestering of transcription factor	9.917353e-4
GO:0006642	triglyceride mobilization	9.962507e-4
GO:0030193	regulation of blood coagulation	1.034995e-3
GO:0006457	protein folding	1.044637e-3
GO:0051648	vesicle localization	1.065126e-3
GO:2000347	positive regulation of hepatocyte proliferation	1.071384e-3
GO:2000349	negative regulation of CD40 signaling pathway	1.071384e-3
GO:0090291	negative regulation of osteoclast proliferation	1.071384e-3
GO:0070429	negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	1.071384e-3
GO:0034148	negative regulation of toll-like receptor 5 signaling pathway	1.071384e-3
GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	1.071384e-3
GO:0072573	tolerance induction to lipopolysaccharide	1.071384e-3
GO:0042420	dopamine catabolic process	1.089912e-3
GO:0002688	regulation of leukocyte chemotaxis	1.093416e-3
GO:0009161	ribonucleoside monophosphate metabolic process	1.096511e-3
GO:0071285	cellular response to lithium ion	1.101447e-3
GO:0090026	positive regulation of monocyte chemotaxis	1.109296e-3
GO:0042312	regulation of vasodilation	1.115540e-3
GO:0010035	response to inorganic substance	1.132281e-3
GO:0032891	negative regulation of organic acid transport	1.139880e-3
GO:0048857	neural nucleus development	1.140965e-3
GO:0045596	negative regulation of cell differentiation	1.145249e-3
GO:0043330	response to exogenous dsRNA	1.149889e-3
GO:0010874	regulation of cholesterol efflux	1.149889e-3
GO:0050690	regulation of defense response to virus by virus	1.157553e-3
GO:0010957	negative regulation of vitamin D biosynthetic process	1.192304e-3
GO:0045736	negative regulation of cyclin-dependent protein kinase activity	1.200366e-3
GO:0045872	positive regulation of rhodopsin gene expression	1.203804e-3
GO:0002462	tolerance induction to nonself antigen	1.203804e-3
GO:0051092	positive regulation of NF-kappaB transcription factor activity	1.204065e-3
GO:0050853	B cell receptor signaling pathway	1.214119e-3
GO:0051650	establishment of vesicle localization	1.232613e-3
GO:0070318	positive regulation of G0 to G1 transition	1.236823e-3
GO:0032879	regulation of localization	1.246491e-3
GO:0006508	proteolysis	1.247639e-3
GO:0060409	positive regulation of acetylcholine metabolic process	1.272787e-3
GO:0006220	pyrimidine nucleotide metabolic process	1.281856e-3
GO:0007568	aging	1.311941e-3
GO:0002832	negative regulation of response to biotic stimulus	1.327808e-3
GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain	1.344458e-3
GO:0010941	regulation of cell death	1.358160e-3
GO:0071888	macrophage apoptosis	1.364160e-3
GO:0040023	establishment of nucleus localization	1.428014e-3
GO:0002764	immune response-regulating signaling pathway	1.435733e-3
GO:0009304	tRNA transcription	1.436556e-3
GO:0048845	venous blood vessel morphogenesis	1.437752e-3
GO:0014812	muscle cell migration	1.437752e-3
GO:0046134	pyrimidine nucleoside biosynthetic process	1.450274e-3
GO:0006538	glutamate catabolic process	1.469602e-3
GO:0031109	microtubule polymerization or depolymerization	1.473513e-3
GO:0014910	regulation of smooth muscle cell migration	1.477570e-3
GO:0042493	response to drug	1.487814e-3
GO:0007281	germ cell development	1.511997e-3
GO:0019220	regulation of phosphate metabolic process	1.557271e-3
GO:0042135	neurotransmitter catabolic process	1.561723e-3
GO:0070316	regulation of G0 to G1 transition	1.582115e-3
GO:0010890	positive regulation of sequestering of triglyceride	1.582115e-3
GO:0060137	maternal process involved in parturition	1.590342e-3
GO:0008219	cell death	1.611811e-3
GO:0050803	regulation of synapse structure and activity	1.616162e-3
GO:0071951	conversion of methionyl-tRNA to N-formyl-methionyl-tRNA	1.633338e-3
GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process	1.633825e-3
GO:0048619	embryonic hindgut morphogenesis	1.689398e-3
GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	1.742380e-3
GO:0010956	negative regulation of calcidiol 1-monooxygenase activity	1.742380e-3
GO:0001504	neurotransmitter uptake	1.750976e-3
GO:0016265	death	1.768135e-3
GO:0016198	axon choice point recognition	1.777526e-3
GO:0042977	activation of JAK2 kinase activity	1.812427e-3
GO:0007368	determination of left/right symmetry	1.848701e-3
GO:0034136	negative regulation of toll-like receptor 2 signaling pathway	1.870161e-3
GO:0072527	pyrimidine-containing compound metabolic process	1.887626e-3
GO:0034059	response to anoxia	1.902902e-3
GO:0000082	G1/S transition of mitotic cell cycle	1.934426e-3
GO:0006766	vitamin metabolic process	1.993892e-3
GO:0002862	negative regulation of inflammatory response to antigenic stimulus	1.999552e-3
GO:0045994	positive regulation of translational initiation by iron	2.006295e-3
GO:0002037	negative regulation of L-glutamate transport	2.006295e-3
GO:0050819	negative regulation of coagulation	2.021753e-3
GO:0006310	DNA recombination	2.036128e-3
GO:0045749	negative regulation of S phase of mitotic cell cycle	2.050117e-3
GO:0042325	regulation of phosphorylation	2.063198e-3
GO:0046796	viral genome transport in host cell	2.065148e-3
GO:0051798	positive regulation of hair follicle development	2.102863e-3
GO:0021999	neural plate anterior/posterior regionalization	2.115936e-3
GO:0061036	positive regulation of cartilage development	2.148300e-3
GO:0050684	regulation of mRNA processing	2.176082e-3
GO:0045351	type I interferon biosynthetic process	2.216338e-3
GO:0042797	tRNA transcription from RNA polymerase III promoter	2.216338e-3
GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter	2.216338e-3
GO:2000379	positive regulation of reactive oxygen species metabolic process	2.226336e-3
GO:0034625	fatty acid elongation, monounsaturated fatty acid	2.238413e-3
GO:0048522	positive regulation of cellular process	2.251635e-3
GO:0034763	negative regulation of transmembrane transport	2.273612e-3
GO:0097118	neuroligin clustering	2.276567e-3
GO:0051341	regulation of oxidoreductase activity	2.296498e-3
GO:0045597	positive regulation of cell differentiation	2.303816e-3
GO:0019216	regulation of lipid metabolic process	2.309338e-3
GO:0080111	DNA demethylation	2.347730e-3
GO:0035729	cellular response to hepatocyte growth factor stimulus	2.347730e-3
GO:0071803	positive regulation of podosome assembly	2.351874e-3
GO:0032886	regulation of microtubule-based process	2.435888e-3
GO:0072321	chaperone-mediated protein transport	2.443493e-3
GO:0051293	establishment of spindle localization	2.448569e-3
GO:0042347	negative regulation of NF-kappaB import into nucleus	2.483117e-3
GO:0002687	positive regulation of leukocyte migration	2.510115e-3
GO:0010701	positive regulation of norepinephrine secretion	2.571576e-3
GO:0001881	receptor recycling	2.571576e-3
GO:0043473	pigmentation	2.588139e-3
GO:0002757	immune response-activating signal transduction	2.605362e-3
GO:0042157	lipoprotein metabolic process	2.625216e-3
GO:0080134	regulation of response to stress	2.655198e-3
GO:0060999	positive regulation of dendritic spine development	2.664365e-3
GO:0060557	positive regulation of vitamin D biosynthetic process	2.668292e-3
GO:0034122	negative regulation of toll-like receptor signaling pathway	2.693301e-3
GO:0006915	apoptosis	2.695157e-3
GO:0032847	regulation of cellular pH reduction	2.706972e-3
GO:0010561	negative regulation of glycoprotein biosynthetic process	2.706972e-3
GO:0048585	negative regulation of response to stimulus	2.743858e-3
GO:0008628	induction of apoptosis by hormones	2.782908e-3
GO:0048016	inositol phosphate-mediated signaling	2.802161e-3
GO:0033574	response to testosterone stimulus	2.820390e-3
GO:0034104	negative regulation of tissue remodeling	2.828138e-3
GO:0032966	negative regulation of collagen biosynthetic process	2.835802e-3
GO:0061046	regulation of branching involved in lung morphogenesis	2.838849e-3
GO:0032754	positive regulation of interleukin-5 production	2.838849e-3
GO:2000739	regulation of mesenchymal stem cell differentiation	2.864664e-3
GO:2000116	regulation of cysteine-type endopeptidase activity	2.890495e-3
GO:2000348	regulation of CD40 signaling pathway	2.950190e-3
GO:0031440	regulation of mRNA 3'-end processing	2.950190e-3
GO:0018095	protein polyglutamylation	2.981594e-3
GO:0046901	tetrahydrofolylpolyglutamate biosynthetic process	2.981594e-3
GO:0032703	negative regulation of interleukin-2 production	2.996067e-3
GO:0051093	negative regulation of developmental process	3.000550e-3
GO:0002676	regulation of chronic inflammatory response	3.005120e-3
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	3.005120e-3
GO:0001662	behavioral fear response	3.008170e-3
GO:0003285	septum secundum development	3.016364e-3
GO:0002669	positive regulation of T cell anergy	3.050670e-3
GO:0060911	cardiac cell fate commitment	3.050670e-3
GO:0021612	facial nerve structural organization	3.091237e-3
GO:0045646	regulation of erythrocyte differentiation	3.095863e-3
GO:0048589	developmental growth	3.112370e-3
GO:2000021	regulation of ion homeostasis	3.121786e-3
GO:0043368	positive T cell selection	3.158545e-3
GO:0070827	chromatin maintenance	3.170931e-3
GO:0035946	mitochondrial mRNA surveillance	3.170931e-3
GO:0035945	mitochondrial ncRNA surveillance	3.170931e-3
GO:0010741	negative regulation of intracellular protein kinase cascade	3.180321e-3
GO:0002360	T cell lineage commitment	3.182668e-3
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	3.200043e-3
GO:0032924	activin receptor signaling pathway	3.283393e-3
GO:0014821	phasic smooth muscle contraction	3.284934e-3
GO:0031532	actin cytoskeleton reorganization	3.293679e-3
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	3.318947e-3
GO:0012501	programmed cell death	3.349603e-3
GO:0010757	negative regulation of plasminogen activation	3.361748e-3
GO:0044254	multicellular organismal protein catabolic process	3.398095e-3
GO:0015891	siderophore transport	3.398095e-3
GO:0032375	negative regulation of cholesterol transport	3.469535e-3
GO:0030509	BMP signaling pathway	3.470947e-3
GO:0046685	response to arsenic-containing substance	3.492158e-3
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	3.497529e-3
GO:0071391	cellular response to estrogen stimulus	3.533744e-3
GO:0015914	phospholipid transport	3.534197e-3
GO:0002682	regulation of immune system process	3.540074e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	2.874225e-16
GO:0002604	regulation of dendritic cell antigen processing and presentation	1.588537e-14
GO:0045796	negative regulation of intestinal cholesterol absorption	3.937400e-13
GO:0010949	negative regulation of intestinal phytosterol absorption	3.937400e-13
GO:0060457	negative regulation of digestive system process	1.884222e-11
GO:0042116	macrophage activation	3.957262e-11
GO:0002579	positive regulation of antigen processing and presentation	9.015978e-11
GO:0002577	regulation of antigen processing and presentation	2.251892e-10
GO:0060008	Sertoli cell differentiation	1.379052e-9
GO:0009123	nucleoside monophosphate metabolic process	1.864066e-9
GO:0015809	arginine transport	2.483611e-9
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	2.732852e-9
GO:0046058	cAMP metabolic process	3.525485e-9
GO:0043252	sodium-independent organic anion transport	3.627879e-9
GO:0060009	Sertoli cell development	4.267603e-9
GO:0072539	T-helper 17 cell differentiation	2.468452e-8
GO:0072521	purine-containing compound metabolic process	5.235791e-8
GO:0032680	regulation of tumor necrosis factor production	5.831112e-8
GO:0006163	purine nucleotide metabolic process	6.061354e-8
GO:0009187	cyclic nucleotide metabolic process	6.083760e-8
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	7.372938e-8
GO:0050862	positive regulation of T cell receptor signaling pathway	1.462357e-7
GO:0035752	lysosomal lumen pH elevation	1.978780e-7
GO:0001575	globoside metabolic process	1.978780e-7
GO:0000046	autophagic vacuole fusion	1.978780e-7
GO:0002720	positive regulation of cytokine production involved in immune response	2.546777e-7
GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	3.178211e-7
GO:0045582	positive regulation of T cell differentiation	4.384055e-7
GO:0071361	cellular response to ethanol	5.730686e-7
GO:0060491	regulation of cell projection assembly	5.773812e-7
GO:0051489	regulation of filopodium assembly	5.946311e-7
GO:0002688	regulation of leukocyte chemotaxis	6.467703e-7
GO:0045919	positive regulation of cytolysis	6.646775e-7
GO:0051491	positive regulation of filopodium assembly	7.206193e-7
GO:0032743	positive regulation of interleukin-2 production	7.566982e-7
GO:0019374	galactolipid metabolic process	7.606491e-7
GO:0002675	positive regulation of acute inflammatory response	8.631987e-7
GO:0044058	regulation of digestive system process	9.429936e-7
GO:0044281	small molecule metabolic process	1.101931e-6
GO:0009117	nucleotide metabolic process	1.132925e-6
GO:0002699	positive regulation of immune effector process	1.208243e-6
GO:0002355	detection of tumor cell	1.413337e-6
GO:0002885	positive regulation of hypersensitivity	1.621011e-6
GO:0030595	leukocyte chemotaxis	1.683269e-6
GO:0055086	nucleobase-containing small molecule metabolic process	1.704263e-6
GO:0045621	positive regulation of lymphocyte differentiation	1.734738e-6
GO:0015939	pantothenate metabolic process	1.819736e-6
GO:0030299	intestinal cholesterol absorption	1.920288e-6
GO:0051454	intracellular pH elevation	1.951850e-6
GO:0016242	negative regulation of macroautophagy	2.001805e-6
GO:0002347	response to tumor cell	2.001805e-6
GO:0015802	basic amino acid transport	2.058801e-6
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	2.144748e-6
GO:0031330	negative regulation of cellular catabolic process	2.187783e-6
GO:0002685	regulation of leukocyte migration	2.675936e-6
GO:0016241	regulation of macroautophagy	2.687826e-6
GO:0032760	positive regulation of tumor necrosis factor production	2.718760e-6
GO:0046700	heterocycle catabolic process	3.101020e-6
GO:0030593	neutrophil chemotaxis	3.113955e-6
GO:0042228	interleukin-8 biosynthetic process	4.694503e-6
GO:0033077	T cell differentiation in thymus	5.240616e-6
GO:0001817	regulation of cytokine production	5.821074e-6
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	6.082016e-6
GO:0035691	macrophage migration inhibitory factor signaling pathway	6.082016e-6
GO:0002718	regulation of cytokine production involved in immune response	6.259600e-6
GO:0010165	response to X-ray	7.750381e-6
GO:0002821	positive regulation of adaptive immune response	8.000437e-6
GO:0006198	cAMP catabolic process	8.329223e-6
GO:0002922	positive regulation of humoral immune response	9.634851e-6
GO:0006681	galactosylceramide metabolic process	9.981664e-6
GO:0090174	organelle membrane fusion	1.016044e-5
GO:0042987	amyloid precursor protein catabolic process	1.033839e-5
GO:0045087	innate immune response	1.072854e-5
GO:0046483	heterocycle metabolic process	1.149050e-5
GO:0072523	purine-containing compound catabolic process	1.162121e-5
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	1.296172e-5
GO:0045060	negative thymic T cell selection	1.334179e-5
GO:0044270	cellular nitrogen compound catabolic process	1.385038e-5
GO:0002726	positive regulation of T cell cytokine production	1.414289e-5
GO:0072610	interleukin-12 secretion	1.439547e-5
GO:0097022	lymphocyte migration into lymph node	1.439547e-5
GO:0050892	intestinal absorption	1.565145e-5
GO:0045820	negative regulation of glycolysis	1.583914e-5
GO:0006195	purine nucleotide catabolic process	1.654354e-5
GO:0009895	negative regulation of catabolic process	1.765136e-5
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	1.874172e-5
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	1.887680e-5
GO:0032023	trypsinogen activation	1.977287e-5
GO:0009190	cyclic nucleotide biosynthetic process	1.997625e-5
GO:0097026	dendritic cell dendrite assembly	1.999057e-5
GO:0006438	valyl-tRNA aminoacylation	1.999057e-5
GO:0090022	regulation of neutrophil chemotaxis	2.018751e-5
GO:0030300	regulation of intestinal cholesterol absorption	2.140491e-5
GO:0006171	cAMP biosynthetic process	2.140491e-5
GO:0032642	regulation of chemokine production	2.148445e-5
GO:0007276	gamete generation	2.170855e-5
GO:0002281	macrophage activation involved in immune response	2.357946e-5
GO:0010758	regulation of macrophage chemotaxis	2.359975e-5
GO:0002883	regulation of hypersensitivity	2.359975e-5
GO:0071675	regulation of mononuclear cell migration	2.599230e-5
GO:2000107	negative regulation of leukocyte apoptosis	2.610176e-5
GO:0090023	positive regulation of neutrophil chemotaxis	2.665843e-5
GO:0009166	nucleotide catabolic process	2.847202e-5
GO:0009259	ribonucleotide metabolic process	2.862430e-5
GO:0009150	purine ribonucleotide metabolic process	2.902878e-5
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	2.963223e-5
GO:0071403	cellular response to high density lipoprotein particle stimulus	3.325931e-5
GO:0071448	cellular response to alkyl hydroperoxide	3.325931e-5
GO:0071315	cellular response to morphine	3.325931e-5
GO:0050904	diapedesis	3.325931e-5
GO:0071307	cellular response to vitamin K	3.325931e-5
GO:0031269	pseudopodium assembly	3.325931e-5
GO:0045123	cellular extravasation	3.451329e-5
GO:0009303	rRNA transcription	3.451329e-5
GO:0001819	positive regulation of cytokine production	3.545110e-5
GO:0032911	negative regulation of transforming growth factor beta1 production	3.632528e-5
GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	3.799007e-5
GO:0010212	response to ionizing radiation	4.103041e-5
GO:0045624	positive regulation of T-helper cell differentiation	4.143083e-5
GO:0072676	lymphocyte migration	4.615677e-5
GO:0002673	regulation of acute inflammatory response	4.709082e-5
GO:0010888	negative regulation of lipid storage	4.881521e-5
GO:0045622	regulation of T-helper cell differentiation	5.340942e-5
GO:0002274	myeloid leukocyte activation	5.515216e-5
GO:0002690	positive regulation of leukocyte chemotaxis	5.665365e-5
GO:0006643	membrane lipid metabolic process	5.831334e-5
GO:0009125	nucleoside monophosphate catabolic process	6.202289e-5
GO:0001516	prostaglandin biosynthetic process	6.302070e-5
GO:0048247	lymphocyte chemotaxis	6.586544e-5
GO:0001960	negative regulation of cytokine-mediated signaling pathway	6.926178e-5
GO:0046034	ATP metabolic process	7.519460e-5
GO:0006678	glucosylceramide metabolic process	7.674040e-5
GO:0034655	nucleobase-containing compound catabolic process	7.735641e-5
GO:0031427	response to methotrexate	8.125424e-5
GO:0006360	transcription from RNA polymerase I promoter	8.520796e-5
GO:0035026	leading edge cell differentiation	8.737840e-5
GO:0002689	negative regulation of leukocyte chemotaxis	9.117290e-5
GO:0072522	purine-containing compound biosynthetic process	9.397206e-5
GO:0001774	microglial cell activation	9.727547e-5
GO:0050775	positive regulation of dendrite morphogenesis	9.853929e-5
GO:0006955	immune response	1.023886e-4
GO:0002518	lymphocyte chemotaxis across high endothelial venule	1.034832e-4
GO:2000412	positive regulation of thymocyte migration	1.034832e-4
GO:0046637	regulation of alpha-beta T cell differentiation	1.038699e-4
GO:0001959	regulation of cytokine-mediated signaling pathway	1.047849e-4
GO:0002702	positive regulation of production of molecular mediator of immune response	1.057564e-4
GO:0016485	protein processing	1.110519e-4
GO:0043383	negative T cell selection	1.116353e-4
GO:0032908	regulation of transforming growth factor beta1 production	1.217318e-4
GO:0010898	positive regulation of triglyceride catabolic process	1.217318e-4
GO:0002830	positive regulation of type 2 immune response	1.231117e-4
GO:0002649	regulation of tolerance induction to self antigen	1.269227e-4
GO:0050778	positive regulation of immune response	1.298336e-4
GO:0072659	protein localization in plasma membrane	1.298992e-4
GO:0032418	lysosome localization	1.304132e-4
GO:0010759	positive regulation of macrophage chemotaxis	1.324412e-4
GO:0060759	regulation of response to cytokine stimulus	1.334792e-4
GO:0007052	mitotic spindle organization	1.351419e-4
GO:0009205	purine ribonucleoside triphosphate metabolic process	1.356698e-4
GO:0010935	regulation of macrophage cytokine production	1.359947e-4
GO:0044241	lipid digestion	1.366245e-4
GO:0048034	heme O biosynthetic process	1.376708e-4
GO:0045226	extracellular polysaccharide biosynthetic process	1.376708e-4
GO:0006693	prostaglandin metabolic process	1.425281e-4
GO:0045061	thymic T cell selection	1.432124e-4
GO:0080135	regulation of cellular response to stress	1.438597e-4
GO:0050900	leukocyte migration	1.445057e-4
GO:0009199	ribonucleoside triphosphate metabolic process	1.455568e-4
GO:0043091	L-arginine import	1.456630e-4
GO:0045342	MHC class II biosynthetic process	1.456630e-4
GO:0060929	atrioventricular node cell fate commitment	1.456630e-4
GO:0070839	divalent metal ion export	1.456630e-4
GO:0060928	atrioventricular node cell development	1.456630e-4
GO:0035470	positive regulation of vascular wound healing	1.456630e-4
GO:0003168	cardiac Purkinje fiber cell differentiation	1.456630e-4
GO:0001923	B-1 B cell differentiation	1.456630e-4
GO:0032632	interleukin-3 production	1.456630e-4
GO:0003342	proepicardium development	1.456630e-4
GO:0006876	cellular cadmium ion homeostasis	1.456630e-4
GO:0015707	nitrite transport	1.456630e-4
GO:0009595	detection of biotic stimulus	1.471090e-4
GO:0007252	I-kappaB phosphorylation	1.506111e-4
GO:0051365	cellular response to potassium ion starvation	1.572169e-4
GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process	1.572169e-4
GO:0050921	positive regulation of chemotaxis	1.595555e-4
GO:0033233	regulation of protein sumoylation	1.612238e-4
GO:0002687	positive regulation of leukocyte migration	1.642876e-4
GO:0050920	regulation of chemotaxis	1.648901e-4
GO:0002230	positive regulation of defense response to virus by host	1.666909e-4
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	1.764845e-4
GO:0000187	activation of MAPK activity	1.883320e-4
GO:0009144	purine nucleoside triphosphate metabolic process	1.954189e-4
GO:0009141	nucleoside triphosphate metabolic process	1.975035e-4
GO:0060326	cell chemotaxis	2.061547e-4
GO:0006665	sphingolipid metabolic process	2.126907e-4
GO:0019953	sexual reproduction	2.189778e-4
GO:0045619	regulation of lymphocyte differentiation	2.233688e-4
GO:0009214	cyclic nucleotide catabolic process	2.237698e-4
GO:0006164	purine nucleotide biosynthetic process	2.256873e-4
GO:0070684	seminal clot liquefaction	2.340675e-4
GO:0061338	atrioventricular node impulse conduction delay	2.454136e-4
GO:0046638	positive regulation of alpha-beta T cell differentiation	2.467433e-4
GO:0010933	positive regulation of macrophage tolerance induction	2.540184e-4
GO:0071671	regulation of smooth muscle cell chemotaxis	2.651116e-4
GO:0031638	zymogen activation	2.700903e-4
GO:0010832	negative regulation of myotube differentiation	2.700903e-4
GO:0002697	regulation of immune effector process	2.734067e-4
GO:0010591	regulation of lamellipodium assembly	2.849209e-4
GO:0045580	regulation of T cell differentiation	2.896067e-4
GO:0009124	nucleoside monophosphate biosynthetic process	2.910420e-4
GO:0071453	cellular response to oxygen levels	2.948318e-4
GO:0042268	regulation of cytolysis	3.003790e-4
GO:0001556	oocyte maturation	3.087646e-4
GO:0002684	positive regulation of immune system process	3.191657e-4
GO:0002906	negative regulation of mature B cell apoptosis	3.247400e-4
GO:0002828	regulation of type 2 immune response	3.275472e-4
GO:0001986	negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure	3.372789e-4
GO:0002643	regulation of tolerance induction	3.372937e-4
GO:0051006	positive regulation of lipoprotein lipase activity	3.556203e-4
GO:0071447	cellular response to hydroperoxide	3.628169e-4
GO:0009167	purine ribonucleoside monophosphate metabolic process	3.698381e-4
GO:0048627	myoblast development	3.855803e-4
GO:0007250	activation of NF-kappaB-inducing kinase activity	3.906831e-4
GO:0010830	regulation of myotube differentiation	3.925320e-4
GO:0033604	negative regulation of catecholamine secretion	3.933891e-4
GO:0051604	protein maturation	4.011785e-4
GO:0016310	phosphorylation	4.087173e-4
GO:2000001	regulation of DNA damage checkpoint	4.101820e-4
GO:0031268	pseudopodium organization	4.101820e-4
GO:0048477	oogenesis	4.121274e-4
GO:0042990	regulation of transcription factor import into nucleus	4.273372e-4
GO:0002861	regulation of inflammatory response to antigenic stimulus	4.310699e-4
GO:0071635	negative regulation of transforming growth factor beta production	4.430989e-4
GO:0042982	amyloid precursor protein metabolic process	4.636629e-4
GO:0001768	establishment of T cell polarity	4.637486e-4
GO:0034695	response to prostaglandin E stimulus	4.911156e-4
GO:0016075	rRNA catabolic process	5.187029e-4
GO:0010700	negative regulation of norepinephrine secretion	5.187029e-4
GO:0002724	regulation of T cell cytokine production	5.255334e-4
GO:0002418	immune response to tumor cell	5.680016e-4
GO:0000966	RNA 5'-end processing	5.680016e-4
GO:0006636	unsaturated fatty acid biosynthetic process	5.817566e-4
GO:0002708	positive regulation of lymphocyte mediated immunity	5.845367e-4
GO:0007281	germ cell development	5.950423e-4
GO:0002309	T cell proliferation involved in immune response	5.956952e-4
GO:0045627	positive regulation of T-helper 1 cell differentiation	5.966274e-4
GO:0046634	regulation of alpha-beta T cell activation	5.987488e-4
GO:0031663	lipopolysaccharide-mediated signaling pathway	6.113664e-4
GO:0006664	glycolipid metabolic process	6.128522e-4
GO:0032615	interleukin-12 production	6.144392e-4
GO:0002407	dendritic cell chemotaxis	6.144392e-4
GO:0030203	glycosaminoglycan metabolic process	6.246399e-4
GO:0034654	nucleobase-containing compound biosynthetic process	6.502002e-4
GO:0045058	T cell selection	6.685225e-4
GO:0001920	negative regulation of receptor recycling	6.785824e-4
GO:0003222	ventricular trabecular myocardium morphogenesis	6.849851e-4
GO:0032736	positive regulation of interleukin-13 production	6.885963e-4
GO:0042994	cytoplasmic sequestering of transcription factor	6.885963e-4
GO:0010891	negative regulation of sequestering of triglyceride	6.885963e-4
GO:0006690	icosanoid metabolic process	7.250042e-4
GO:0009154	purine ribonucleotide catabolic process	7.392333e-4
GO:0006796	phosphate-containing compound metabolic process	7.403203e-4
GO:0043525	positive regulation of neuron apoptosis	7.598615e-4
GO:0010592	positive regulation of lamellipodium assembly	7.653723e-4
GO:0043249	erythrocyte maturation	7.653723e-4
GO:0009261	ribonucleotide catabolic process	7.873248e-4
GO:0032722	positive regulation of chemokine production	8.047205e-4
GO:0050854	regulation of antigen receptor-mediated signaling pathway	8.078245e-4
GO:0061337	cardiac conduction	8.278929e-4
GO:0050776	regulation of immune response	8.485507e-4
GO:0032103	positive regulation of response to external stimulus	8.522423e-4
GO:0032847	regulation of cellular pH reduction	8.529228e-4
GO:0001544	initiation of primordial ovarian follicle growth	8.756504e-4
GO:0051725	protein de-ADP-ribosylation	9.077091e-4
GO:0000073	spindle pole body separation	9.077091e-4
GO:0009165	nucleotide biosynthetic process	9.083125e-4
GO:0051930	regulation of sensory perception of pain	9.480380e-4
GO:0009161	ribonucleoside monophosphate metabolic process	9.668106e-4
GO:0042177	negative regulation of protein catabolic process	9.843442e-4
GO:0002286	T cell activation involved in immune response	9.971149e-4
GO:0071622	regulation of granulocyte chemotaxis	9.977281e-4
GO:0015914	phospholipid transport	1.007502e-3
GO:0050996	positive regulation of lipid catabolic process	1.009632e-3
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	1.012839e-3
GO:0010889	regulation of sequestering of triglyceride	1.025818e-3
GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity	1.032557e-3
GO:0002070	epithelial cell maturation	1.032557e-3
GO:0042246	tissue regeneration	1.044933e-3
GO:0042345	regulation of NF-kappaB import into nucleus	1.050405e-3
GO:0002825	regulation of T-helper 1 type immune response	1.066705e-3
GO:0018130	heterocycle biosynthetic process	1.080312e-3
GO:0010430	fatty acid omega-oxidation	1.102744e-3
GO:0002357	defense response to tumor cell	1.102744e-3
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	1.108306e-3
GO:0034340	response to type I interferon	1.112333e-3
GO:0009258	10-formyltetrahydrofolate catabolic process	1.112333e-3
GO:0003417	growth plate cartilage development	1.113453e-3
GO:2000401	regulation of lymphocyte migration	1.127212e-3
GO:0002764	immune response-regulating signaling pathway	1.145595e-3
GO:0071347	cellular response to interleukin-1	1.151355e-3
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	1.167987e-3
GO:0043406	positive regulation of MAP kinase activity	1.184824e-3
GO:0071731	response to nitric oxide	1.188659e-3
GO:0071504	cellular response to heparin	1.192195e-3
GO:0006756	AMP phosphorylation	1.270484e-3
GO:0090208	positive regulation of triglyceride metabolic process	1.273833e-3
GO:0055117	regulation of cardiac muscle contraction	1.301086e-3
GO:0030204	chondroitin sulfate metabolic process	1.313042e-3
GO:0032849	positive regulation of cellular pH reduction	1.322633e-3
GO:0002757	immune response-activating signal transduction	1.326614e-3
GO:0055099	response to high density lipoprotein particle stimulus	1.364435e-3
GO:0002376	immune system process	1.374493e-3
GO:0046958	nonassociative learning	1.393250e-3
GO:0015886	heme transport	1.393250e-3
GO:0000165	MAPKKK cascade	1.408398e-3
GO:0032108	negative regulation of response to nutrient levels	1.414365e-3
GO:0050795	regulation of behavior	1.434392e-3
GO:0080134	regulation of response to stress	1.444690e-3
GO:0002891	positive regulation of immunoglobulin mediated immune response	1.446467e-3
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	1.459538e-3
GO:0046037	GMP metabolic process	1.472481e-3
GO:0043519	regulation of myosin II filament organization	1.472481e-3
GO:0071503	response to heparin	1.473462e-3
GO:0042098	T cell proliferation	1.488692e-3
GO:0045059	positive thymic T cell selection	1.519741e-3
GO:0097117	guanylate kinase-associated protein clustering	1.520167e-3
GO:0097114	N-methyl-D-aspartate receptor clustering	1.520167e-3
GO:0015670	carbon dioxide transport	1.520167e-3
GO:0097112	gamma-aminobutyric acid receptor clustering	1.520167e-3
GO:0051545	negative regulation of elastin biosynthetic process	1.537863e-3
GO:0006952	defense response	1.570258e-3
GO:0050853	B cell receptor signaling pathway	1.572937e-3
GO:0042346	positive regulation of NF-kappaB import into nucleus	1.615916e-3
GO:0010896	regulation of triglyceride catabolic process	1.623295e-3
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	1.644808e-3
GO:0046456	icosanoid biosynthetic process	1.649111e-3
GO:0009207	purine ribonucleoside triphosphate catabolic process	1.650614e-3
GO:0048609	multicellular organismal reproductive process	1.713133e-3
GO:0071544	diphosphoinositol polyphosphate catabolic process	1.723609e-3
GO:2000110	negative regulation of macrophage apoptosis	1.723609e-3
GO:0071673	positive regulation of smooth muscle cell chemotaxis	1.723609e-3
GO:0006433	prolyl-tRNA aminoacylation	1.723609e-3
GO:0032203	telomere formation via telomerase	1.723609e-3
GO:0060971	embryonic heart tube left/right pattern formation	1.723609e-3
GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process	1.739931e-3
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	1.758055e-3
GO:0001961	positive regulation of cytokine-mediated signaling pathway	1.762828e-3
GO:0051929	positive regulation of calcium ion transport via voltage-gated calcium channel activity	1.805687e-3
GO:0006200	ATP catabolic process	1.835832e-3
GO:0046635	positive regulation of alpha-beta T cell activation	1.861640e-3
GO:0032902	nerve growth factor production	1.894015e-3
GO:0050766	positive regulation of phagocytosis	1.912945e-3
GO:0009143	nucleoside triphosphate catabolic process	1.919180e-3
GO:0006022	aminoglycan metabolic process	1.945818e-3
GO:0002920	regulation of humoral immune response	1.959964e-3
GO:0006468	protein phosphorylation	1.984042e-3
GO:0032754	positive regulation of interleukin-5 production	1.992879e-3
GO:0001798	positive regulation of type IIa hypersensitivity	1.995084e-3
GO:0051453	regulation of intracellular pH	2.024553e-3
GO:0009146	purine nucleoside triphosphate catabolic process	2.024669e-3
GO:0002224	toll-like receptor signaling pathway	2.070530e-3
GO:0071267	L-methionine salvage	2.106830e-3
GO:0032101	regulation of response to external stimulus	2.184491e-3
GO:0090303	positive regulation of wound healing	2.210814e-3
GO:0007283	spermatogenesis	2.268990e-3
GO:0046940	nucleoside monophosphate phosphorylation	2.277713e-3
GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway	2.277713e-3
GO:0003278	apoptosis involved in heart morphogenesis	2.277713e-3
GO:0007028	cytoplasm organization	2.310300e-3
GO:0051607	defense response to virus	2.459182e-3
GO:0070932	histone H3 deacetylation	2.549218e-3
GO:0071456	cellular response to hypoxia	2.552027e-3
GO:0048384	retinoic acid receptor signaling pathway	2.556949e-3
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	2.589780e-3
GO:0002819	regulation of adaptive immune response	2.593797e-3
GO:0006516	glycoprotein catabolic process	2.609420e-3
GO:0048537	mucosal-associated lymphoid tissue development	2.609420e-3
GO:0002478	antigen processing and presentation of exogenous peptide antigen	2.634198e-3
GO:0048610	cellular process involved in reproduction	2.661467e-3
GO:0003416	endochondral bone growth	2.783622e-3
GO:0060760	positive regulation of response to cytokine stimulus	2.816723e-3
GO:0070229	negative regulation of lymphocyte apoptosis	2.892260e-3
GO:0034661	ncRNA catabolic process	2.901787e-3
GO:0032107	regulation of response to nutrient levels	2.930066e-3
GO:0021570	rhombomere 4 development	2.943199e-3
GO:0016554	cytidine to uridine editing	2.962171e-3
GO:0051452	intracellular pH reduction	3.033566e-3
GO:0060676	ureteric bud formation	3.037373e-3
GO:0051639	actin filament network formation	3.055233e-3
GO:0045343	regulation of MHC class I biosynthetic process	3.055233e-3
GO:0032571	response to vitamin K	3.055233e-3
GO:0006937	regulation of muscle contraction	3.100924e-3
GO:0032374	regulation of cholesterol transport	3.108604e-3
GO:0006687	glycosphingolipid metabolic process	3.134127e-3
GO:0060907	positive regulation of macrophage cytokine production	3.143773e-3
GO:0007042	lysosomal lumen acidification	3.231396e-3
GO:0001816	cytokine production	3.236611e-3
GO:0002686	negative regulation of leukocyte migration	3.263620e-3
GO:0045823	positive regulation of heart contraction	3.308472e-3
GO:0045861	negative regulation of proteolysis	3.366829e-3
GO:0045625	regulation of T-helper 1 cell differentiation	3.464783e-3
GO:0018149	peptide cross-linking	3.565482e-3
GO:0010507	negative regulation of autophagy	3.577924e-3
GO:0002711	positive regulation of T cell mediated immunity	3.613945e-3
GO:0019276	UDP-N-acetylgalactosamine metabolic process	3.629817e-3
GO:0006784	heme a biosynthetic process	3.629817e-3
GO:0007127	meiosis I	3.639724e-3
GO:0007249	I-kappaB kinase/NF-kappaB cascade	3.683366e-3
GO:0072303	positive regulation of glomerular metanephric mesangial cell proliferation	3.730158e-3
GO:0008582	regulation of synaptic growth at neuromuscular junction	3.730158e-3
GO:0007144	female meiosis I	3.730158e-3
GO:0032880	regulation of protein localization	3.732498e-3
GO:0010820	positive regulation of T cell chemotaxis	3.765645e-3
GO:0006477	protein sulfation	3.776672e-3
GO:0060754	positive regulation of mast cell chemotaxis	3.837112e-3
GO:0016045	detection of bacterium	3.837112e-3
GO:0002051	osteoblast fate commitment	3.837112e-3
GO:0051085	chaperone mediated protein folding requiring cofactor	3.845943e-3
GO:0007530	sex determination	3.861920e-3
GO:0001974	blood vessel remodeling	4.011628e-3
GO:2000406	positive regulation of T cell migration	4.038784e-3
GO:0050663	cytokine secretion	4.089915e-3
GO:0048599	oocyte development	4.091829e-3
GO:0051209	release of sequestered calcium ion into cytosol	4.133313e-3
GO:0007193	inhibition of adenylate cyclase activity by G-protein signaling pathway	4.133698e-3
GO:0072657	protein localization in membrane	4.149339e-3
GO:0051220	cytoplasmic sequestering of protein	4.150320e-3
GO:0035196	production of miRNAs involved in gene silencing by miRNA	4.150320e-3
GO:0046086	adenosine biosynthetic process	4.238097e-3
GO:0006196	AMP catabolic process	4.238097e-3
GO:0046640	regulation of alpha-beta T cell proliferation	4.251602e-3
GO:0060010	Sertoli cell fate commitment	4.277898e-3
GO:0051127	positive regulation of actin nucleation	4.277898e-3
GO:0050994	regulation of lipid catabolic process	4.390917e-3
GO:0043410	positive regulation of MAPKKK cascade	4.406716e-3
GO:0007588	excretion	4.455286e-3
GO:0008052	sensory organ boundary specification	4.493012e-3
GO:0035522	monoubiquitinated histone H2A deubiquitination	4.493012e-3
GO:0007402	ganglion mother cell fate determination	4.493012e-3
GO:0042992	negative regulation of transcription factor import into nucleus	4.510537e-3
GO:0048535	lymph node development	4.523507e-3
GO:0010559	regulation of glycoprotein biosynthetic process	4.628592e-3
GO:0007035	vacuolar acidification	4.648301e-3
GO:2001020	regulation of response to DNA damage stimulus	4.737932e-3
GO:0002700	regulation of production of molecular mediator of immune response	4.824928e-3
GO:0031054	pre-miRNA processing	4.845600e-3
GO:0051891	positive regulation of cardioblast differentiation	4.939413e-3
GO:0030252	growth hormone secretion	5.003665e-3
GO:0060296	regulation of cilium beat frequency involved in ciliary motility	5.015592e-3
GO:0070201	regulation of establishment of protein localization	5.029634e-3
GO:0046328	regulation of JNK cascade	5.046605e-3
GO:0018298	protein-chromophore linkage	5.069692e-3
GO:0033194	response to hydroperoxide	5.251889e-3
GO:0032102	negative regulation of response to external stimulus	5.374988e-3
GO:0006029	proteoglycan metabolic process	5.439302e-3
GO:0051154	negative regulation of striated muscle cell differentiation	5.562466e-3
GO:0007184	SMAD protein import into nucleus	5.579881e-3
GO:0042093	T-helper cell differentiation	5.650036e-3
GO:0043331	response to dsRNA	5.697698e-3
GO:0051615	histamine uptake	5.706893e-3
GO:0034112	positive regulation of homotypic cell-cell adhesion	5.706893e-3
GO:0006424	glutamyl-tRNA aminoacylation	5.706893e-3
GO:0032608	interferon-beta production	5.706893e-3
GO:0007004	telomere maintenance via telomerase	5.706893e-3
GO:0060586	multicellular organismal iron ion homeostasis	5.814041e-3
GO:0030046	parallel actin filament bundle assembly	5.814041e-3
GO:0009994	oocyte differentiation	5.826158e-3
GO:0043368	positive T cell selection	5.863770e-3
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	5.866519e-3
GO:0045638	negative regulation of myeloid cell differentiation	5.980442e-3
GO:0045851	pH reduction	6.025800e-3
GO:0002253	activation of immune response	6.074595e-3
GO:0007292	female gamete generation	6.121238e-3
GO:0050688	regulation of defense response to virus	6.133614e-3
GO:0032874	positive regulation of stress-activated MAPK cascade	6.135608e-3
GO:0043278	response to morphine	6.196154e-3
GO:0006790	sulfur compound metabolic process	6.244785e-3
GO:0051045	negative regulation of membrane protein ectodomain proteolysis	6.284533e-3
GO:0019752	carboxylic acid metabolic process	6.347626e-3
GO:0070257	positive regulation of mucus secretion	6.364017e-3
GO:0003085	negative regulation of systemic arterial blood pressure	6.384535e-3
GO:0070302	regulation of stress-activated protein kinase signaling cascade	6.556811e-3
GO:0007183	SMAD protein complex assembly	6.584061e-3
GO:0015780	nucleotide-sugar transport	6.750054e-3
GO:0006119	oxidative phosphorylation	6.836022e-3
GO:0034113	heterotypic cell-cell adhesion	6.848206e-3
GO:0043403	skeletal muscle tissue regeneration	6.890950e-3
GO:0006189	'de novo' IMP biosynthetic process	6.914703e-3
GO:0008156	negative regulation of DNA replication	6.941731e-3
GO:0042993	positive regulation of transcription factor import into nucleus	6.957768e-3
GO:0002903	negative regulation of B cell apoptosis	7.113698e-3
GO:0044255	cellular lipid metabolic process	7.128584e-3
GO:0060371	regulation of atrial cardiomyocyte membrane depolarization	7.157959e-3
GO:0070555	response to interleukin-1	7.161159e-3
GO:0042180	cellular ketone metabolic process	7.267418e-3
GO:0016080	synaptic vesicle targeting	7.271810e-3
GO:0030641	regulation of cellular pH	7.409175e-3
GO:0033235	positive regulation of protein sumoylation	7.422012e-3
GO:0005513	detection of calcium ion	7.422012e-3
GO:0001970	positive regulation of activation of membrane attack complex	7.422012e-3