Novel motif:154

name:	motif154_GRWGGCAARCG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0006359	regulation of transcription from RNA polymerase III promoter	9.510165e-10
GO:0008612	peptidyl-lysine modification to hypusine	2.423688e-8
GO:0015858	nucleoside transport	4.683681e-8
GO:0018208	peptidyl-proline modification	6.227374e-8
GO:0007522	visceral muscle development	6.911573e-8
GO:0045652	regulation of megakaryocyte differentiation	8.513926e-8
GO:0060669	embryonic placenta morphogenesis	1.633239e-7
GO:0000379	tRNA-type intron splice site recognition and cleavage	2.763103e-7
GO:0060216	definitive hemopoiesis	3.592145e-7
GO:0060070	canonical Wnt receptor signaling pathway	6.088694e-7
GO:0060828	regulation of canonical Wnt receptor signaling pathway	6.323922e-7
GO:0032964	collagen biosynthetic process	1.449499e-6
GO:0051488	activation of anaphase-promoting complex activity	1.479226e-6
GO:0050975	sensory perception of touch	1.905056e-6
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	1.935613e-6
GO:0030431	sleep	2.112258e-6
GO:0034447	very-low-density lipoprotein particle clearance	2.160016e-6
GO:0000413	protein peptidyl-prolyl isomerization	2.306836e-6
GO:0045905	positive regulation of translational termination	2.418630e-6
GO:0045901	positive regulation of translational elongation	2.418630e-6
GO:0006452	translational frameshifting	2.418630e-6
GO:0042270	protection from natural killer cell mediated cytotoxicity	2.429187e-6
GO:0035357	peroxisome proliferator activated receptor signaling pathway	2.633634e-6
GO:0045415	negative regulation of interleukin-8 biosynthetic process	3.063328e-6
GO:0045654	positive regulation of megakaryocyte differentiation	3.201846e-6
GO:0006449	regulation of translational termination	3.579872e-6
GO:0022009	central nervous system vasculogenesis	4.645084e-6
GO:0033233	regulation of protein sumoylation	5.894754e-6
GO:0061028	establishment of endothelial barrier	7.043044e-6
GO:0030111	regulation of Wnt receptor signaling pathway	7.164727e-6
GO:0060346	bone trabecula formation	7.592892e-6
GO:0055009	atrial cardiac muscle tissue morphogenesis	7.924092e-6
GO:0060670	branching involved in embryonic placenta morphogenesis	9.351491e-6
GO:0030953	astral microtubule organization	9.550521e-6
GO:0002268	follicular dendritic cell differentiation	9.792320e-6
GO:0030309	poly-N-acetyllactosamine metabolic process	9.877730e-6
GO:0034505	tooth mineralization	1.088199e-5
GO:0032006	regulation of TOR signaling cascade	1.190448e-5
GO:0070345	negative regulation of fat cell proliferation	1.518852e-5
GO:0050690	regulation of defense response to virus by virus	1.538481e-5
GO:0055012	ventricular cardiac muscle cell differentiation	1.755084e-5
GO:0001694	histamine biosynthetic process	1.867688e-5
GO:0045064	T-helper 2 cell differentiation	1.867688e-5
GO:0045575	basophil activation	1.867688e-5
GO:0002315	marginal zone B cell differentiation	1.867688e-5
GO:0045820	negative regulation of glycolysis	1.896663e-5
GO:0031668	cellular response to extracellular stimulus	1.967551e-5
GO:0072526	pyridine-containing compound catabolic process	2.048513e-5
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	2.252920e-5
GO:0003002	regionalization	2.463083e-5
GO:0045112	integrin biosynthetic process	2.602987e-5
GO:0032008	positive regulation of TOR signaling cascade	2.611837e-5
GO:0003108	negative regulation of the force of heart contraction by chemical signal	2.955025e-5
GO:0007379	segment specification	3.272469e-5
GO:0003057	regulation of the force of heart contraction by chemical signal	3.295931e-5
GO:0045414	regulation of interleukin-8 biosynthetic process	3.660076e-5
GO:0007006	mitochondrial membrane organization	3.863230e-5
GO:0009792	embryo development ending in birth or egg hatching	3.879329e-5
GO:0030311	poly-N-acetyllactosamine biosynthetic process	4.040802e-5
GO:0048384	retinoic acid receptor signaling pathway	4.370394e-5
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	4.387657e-5
GO:0003230	cardiac atrium development	4.445809e-5
GO:0003209	cardiac atrium morphogenesis	5.210572e-5
GO:0010624	regulation of Schwann cell proliferation	5.419098e-5
GO:0048260	positive regulation of receptor-mediated endocytosis	6.057800e-5
GO:0006513	protein monoubiquitination	6.448345e-5
GO:0035854	eosinophil fate commitment	6.957600e-5
GO:0030222	eosinophil differentiation	6.957600e-5
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	7.255813e-5
GO:0002026	regulation of the force of heart contraction	7.427526e-5
GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase	7.547721e-5
GO:0016055	Wnt receptor signaling pathway	8.127230e-5
GO:0030277	maintenance of gastrointestinal epithelium	8.144125e-5
GO:0001661	conditioned taste aversion	8.440761e-5
GO:0040015	negative regulation of multicellular organism growth	8.474418e-5
GO:0016188	synaptic vesicle maturation	8.675091e-5
GO:0030177	positive regulation of Wnt receptor signaling pathway	8.689692e-5
GO:0006457	protein folding	8.804673e-5
GO:0002029	desensitization of G-protein coupled receptor protein signaling pathway	9.056472e-5
GO:0032506	cytokinetic process	1.073492e-4
GO:0043009	chordate embryonic development	1.094720e-4
GO:0061383	trabecula morphogenesis	1.123748e-4
GO:0048488	synaptic vesicle endocytosis	1.223509e-4
GO:0048702	embryonic neurocranium morphogenesis	1.276444e-4
GO:0045653	negative regulation of megakaryocyte differentiation	1.276444e-4
GO:0060343	trabecula formation	1.343635e-4
GO:0048755	branching morphogenesis of a nerve	1.346405e-4
GO:0042696	menarche	1.351543e-4
GO:0031330	negative regulation of cellular catabolic process	1.422718e-4
GO:0072268	pattern specification involved in metanephros development	1.440411e-4
GO:0048706	embryonic skeletal system development	1.486793e-4
GO:0007585	respiratory gaseous exchange	1.491515e-4
GO:0032088	negative regulation of NF-kappaB transcription factor activity	1.521676e-4
GO:0072133	metanephric mesenchyme morphogenesis	1.521787e-4
GO:0033235	positive regulation of protein sumoylation	1.535241e-4
GO:0051764	actin crosslink formation	1.536655e-4
GO:0006333	chromatin assembly or disassembly	1.608229e-4
GO:2000370	positive regulation of clathrin-mediated endocytosis	1.655360e-4
GO:0045234	protein palmitoleylation	1.655360e-4
GO:0006948	induction by virus of host cell-cell fusion	1.655360e-4
GO:0072075	metanephric mesenchyme development	1.690606e-4
GO:0035518	histone H2A monoubiquitination	1.810083e-4
GO:0048790	maintenance of presynaptic active zone structure	1.829510e-4
GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane	1.829510e-4
GO:0043149	stress fiber assembly	1.851735e-4
GO:0060339	negative regulation of type I interferon-mediated signaling pathway	1.901386e-4
GO:0072162	metanephric mesenchymal cell differentiation	1.927190e-4
GO:0000920	cytokinetic cell separation	2.044195e-4
GO:0060535	trachea cartilage morphogenesis	2.073542e-4
GO:0010390	histone monoubiquitination	2.125354e-4
GO:0060534	trachea cartilage development	2.166108e-4
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	2.169050e-4
GO:0060484	lung-associated mesenchyme development	2.227141e-4
GO:0002069	columnar/cuboidal epithelial cell maturation	2.268440e-4
GO:0001692	histamine metabolic process	2.379641e-4
GO:0030219	megakaryocyte differentiation	2.442696e-4
GO:0035313	wound healing, spreading of epidermal cells	2.662887e-4
GO:0051438	regulation of ubiquitin-protein ligase activity	2.685913e-4
GO:0046491	L-methylmalonyl-CoA metabolic process	2.720591e-4
GO:0071934	thiamine transmembrane transport	2.720591e-4
GO:0070078	histone H3-R2 demethylation	2.772184e-4
GO:0070079	histone H4-R3 demethylation	2.772184e-4
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	2.772184e-4
GO:0006438	valyl-tRNA aminoacylation	2.772184e-4
GO:0071496	cellular response to external stimulus	2.842470e-4
GO:0090102	cochlea development	2.932285e-4
GO:0051403	stress-activated MAPK cascade	2.941691e-4
GO:0001885	endothelial cell development	3.026862e-4
GO:0006337	nucleosome disassembly	3.049521e-4
GO:0090342	regulation of cell aging	3.094834e-4
GO:0009048	dosage compensation, by inactivation of X chromosome	3.202088e-4
GO:0071333	cellular response to glucose stimulus	3.294356e-4
GO:0031324	negative regulation of cellular metabolic process	3.730788e-4
GO:0032312	regulation of ARF GTPase activity	3.851377e-4
GO:0070483	detection of hypoxia	3.905559e-4
GO:0010171	body morphogenesis	4.033324e-4
GO:0021633	optic nerve structural organization	4.065987e-4
GO:2000597	positive regulation of optic nerve formation	4.065987e-4
GO:0061360	optic chiasma development	4.065987e-4
GO:0035799	ureter maturation	4.065987e-4
GO:0021650	vestibulocochlear nerve formation	4.065987e-4
GO:0044259	multicellular organismal macromolecule metabolic process	4.173480e-4
GO:0060323	head morphogenesis	4.200098e-4
GO:0046724	oxalic acid secretion	4.495461e-4
GO:0019265	glycine biosynthetic process, by transamination of glyoxylate	4.495461e-4
GO:0046902	regulation of mitochondrial membrane permeability	4.510060e-4
GO:0090103	cochlea morphogenesis	4.595894e-4
GO:0072194	kidney smooth muscle tissue development	4.751015e-4
GO:0007109	cytokinesis, completion of separation	4.784650e-4
GO:0021528	commissural neuron differentiation in spinal cord	4.862997e-4
GO:0032233	positive regulation of actin filament bundle assembly	4.883866e-4
GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	4.949825e-4
GO:0032425	positive regulation of mismatch repair	4.985738e-4
GO:0031396	regulation of protein ubiquitination	5.003517e-4
GO:0010832	negative regulation of myotube differentiation	5.029949e-4
GO:2000210	positive regulation of anoikis	5.161349e-4
GO:0072272	proximal/distal pattern formation involved in metanephric nephron development	5.167702e-4
GO:0032012	regulation of ARF protein signal transduction	5.229125e-4
GO:0006206	pyrimidine base metabolic process	5.434802e-4
GO:0032963	collagen metabolic process	5.474157e-4
GO:0019370	leukotriene biosynthetic process	5.551455e-4
GO:0010558	negative regulation of macromolecule biosynthetic process	5.732218e-4
GO:0030327	prenylated protein catabolic process	5.814613e-4
GO:0048705	skeletal system morphogenesis	5.963504e-4
GO:0034126	positive regulation of MyD88-dependent toll-like receptor signaling pathway	6.015018e-4
GO:0007217	tachykinin receptor signaling pathway	6.049258e-4
GO:0031397	negative regulation of protein ubiquitination	6.084818e-4
GO:0043585	nose morphogenesis	6.145030e-4
GO:0006338	chromatin remodeling	6.514817e-4
GO:0045585	positive regulation of cytotoxic T cell differentiation	6.590057e-4
GO:0002448	mast cell mediated immunity	6.639526e-4
GO:0071322	cellular response to carbohydrate stimulus	7.125883e-4
GO:0034728	nucleosome organization	7.145723e-4
GO:0033689	negative regulation of osteoblast proliferation	7.176697e-4
GO:0018199	peptidyl-glutamine modification	7.246512e-4
GO:0072134	nephrogenic mesenchyme morphogenesis	7.391789e-4
GO:0010605	negative regulation of macromolecule metabolic process	7.946354e-4
GO:0045945	positive regulation of transcription from RNA polymerase III promoter	8.122702e-4
GO:0001909	leukocyte mediated cytotoxicity	8.406206e-4
GO:0046339	diacylglycerol metabolic process	8.632230e-4
GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	8.757062e-4
GO:0022027	interkinetic nuclear migration	8.757062e-4
GO:0016574	histone ubiquitination	9.090021e-4
GO:0010625	positive regulation of Schwann cell proliferation	9.121741e-4
GO:0051445	regulation of meiotic cell cycle	9.329981e-4
GO:0010310	regulation of hydrogen peroxide metabolic process	9.759526e-4
GO:0014037	Schwann cell differentiation	9.779315e-4
GO:0021759	globus pallidus development	9.820759e-4
GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter	9.820759e-4
GO:0060325	face morphogenesis	1.004239e-3
GO:0046101	hypoxanthine biosynthetic process	1.005344e-3
GO:0046967	cytosol to ER transport	1.010282e-3
GO:0044236	multicellular organismal metabolic process	1.014167e-3
GO:0034198	cellular response to amino acid starvation	1.029122e-3
GO:0072189	ureter development	1.055206e-3
GO:0072061	inner medullary collecting duct development	1.097650e-3
GO:0072060	outer medullary collecting duct development	1.097650e-3
GO:0016332	establishment or maintenance of polarity of embryonic epithelium	1.097650e-3
GO:0000416	positive regulation of histone H3-K36 methylation	1.111597e-3
GO:0035110	leg morphogenesis	1.119327e-3
GO:0015788	UDP-N-acetylglucosamine transport	1.132476e-3
GO:0002071	glandular epithelial cell maturation	1.132476e-3
GO:0007257	activation of JUN kinase activity	1.170269e-3
GO:0016568	chromatin modification	1.425184e-3
GO:0031064	negative regulation of histone deacetylation	1.442782e-3
GO:0044319	wound healing, spreading of cells	1.461666e-3
GO:0014044	Schwann cell development	1.463468e-3
GO:0003229	ventricular cardiac muscle tissue development	1.465278e-3
GO:0072126	positive regulation of glomerular mesangial cell proliferation	1.467610e-3
GO:0071506	cellular response to mycophenolic acid	1.467610e-3
GO:0042538	hyperosmotic salinity response	1.470373e-3
GO:0021892	cerebral cortex GABAergic interneuron differentiation	1.474673e-3
GO:0021562	vestibulocochlear nerve development	1.515013e-3
GO:0007296	vitellogenesis	1.543846e-3
GO:0021707	cerebellar granule cell differentiation	1.554897e-3
GO:0070208	protein heterotrimerization	1.577049e-3
GO:2000617	positive regulation of histone H3-K9 acetylation	1.620533e-3
GO:0070512	positive regulation of histone H4-K20 methylation	1.620533e-3
GO:2000620	positive regulation of histone H4-K16 acetylation	1.620533e-3
GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response	1.620533e-3
GO:0006742	NADP catabolic process	1.620533e-3
GO:0043497	regulation of protein heterodimerization activity	1.625532e-3
GO:0046755	non-lytic virus budding	1.656681e-3
GO:0045892	negative regulation of transcription, DNA-dependent	1.730180e-3
GO:0060706	cell differentiation involved in embryonic placenta development	1.737991e-3
GO:0007028	cytoplasm organization	1.742295e-3
GO:0055010	ventricular cardiac muscle tissue morphogenesis	1.763693e-3
GO:0010742	macrophage derived foam cell differentiation	1.772569e-3
GO:0002067	glandular epithelial cell differentiation	1.779696e-3
GO:0046100	hypoxanthine metabolic process	1.796240e-3
GO:0002540	leukotriene production involved in inflammatory response	1.834052e-3
GO:0071300	cellular response to retinoic acid	1.843351e-3
GO:0042398	cellular modified amino acid biosynthetic process	1.848599e-3
GO:0071299	cellular response to vitamin A	1.864645e-3
GO:0040020	regulation of meiosis	1.888153e-3
GO:0007249	I-kappaB kinase/NF-kappaB cascade	1.937274e-3
GO:0031327	negative regulation of cellular biosynthetic process	2.018800e-3
GO:0034138	toll-like receptor 3 signaling pathway	2.028022e-3
GO:0000154	rRNA modification	2.103790e-3
GO:0034389	lipid particle organization	2.108988e-3
GO:0021683	cerebellar granular layer morphogenesis	2.140491e-3
GO:0032456	endocytic recycling	2.143491e-3
GO:0051172	negative regulation of nitrogen compound metabolic process	2.146464e-3
GO:0006448	regulation of translational elongation	2.155072e-3
GO:0060395	SMAD protein signal transduction	2.160039e-3
GO:0051253	negative regulation of RNA metabolic process	2.244007e-3
GO:0035811	negative regulation of urine volume	2.283824e-3
GO:0060020	Bergmann glial cell differentiation	2.300334e-3
GO:0008298	intracellular mRNA localization	2.335490e-3
GO:0019048	virus-host interaction	2.360278e-3
GO:0030328	prenylcysteine catabolic process	2.380447e-3
GO:0022011	myelination in peripheral nervous system	2.387628e-3
GO:0060154	cellular process regulating host cell cycle in response to virus	2.403456e-3
GO:0021508	floor plate formation	2.425482e-3
GO:0015862	uridine transport	2.425482e-3
GO:0018209	peptidyl-serine modification	2.442998e-3
GO:0034721	histone H3-K4 demethylation, trimethyl-H3-K4-specific	2.463429e-3
GO:0016191	synaptic vesicle uncoating	2.463429e-3
GO:0008616	queuosine biosynthetic process	2.463429e-3
GO:0010669	epithelial structure maintenance	2.464993e-3
GO:0072195	kidney smooth muscle cell differentiation	2.479654e-3
GO:0072105	ureteric peristalsis	2.479654e-3
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	2.479654e-3
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	2.479654e-3
GO:0060252	positive regulation of glial cell proliferation	2.547136e-3
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	2.547652e-3
GO:0009890	negative regulation of biosynthetic process	2.626612e-3
GO:0031935	regulation of chromatin silencing	2.663684e-3
GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure	2.682547e-3
GO:0008588	release of cytoplasmic sequestered NF-kappaB	2.710790e-3
GO:0042149	cellular response to glucose starvation	2.748416e-3
GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	2.749528e-3
GO:0031669	cellular response to nutrient levels	2.766868e-3
GO:0051340	regulation of ligase activity	2.828917e-3
GO:0060351	cartilage development involved in endochondral bone morphogenesis	2.834399e-3
GO:0010225	response to UV-C	2.842907e-3
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	2.843690e-3
GO:0046543	development of secondary female sexual characteristics	2.849348e-3
GO:0018105	peptidyl-serine phosphorylation	2.930341e-3
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	3.076312e-3
GO:0034699	response to luteinizing hormone stimulus	3.076312e-3
GO:0045556	positive regulation of TRAIL biosynthetic process	3.089370e-3
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	3.143555e-3
GO:0001892	embryonic placenta development	3.205190e-3
GO:0007350	blastoderm segmentation	3.218116e-3
GO:0006691	leukotriene metabolic process	3.233441e-3
GO:0042770	signal transduction in response to DNA damage	3.276457e-3
GO:0046134	pyrimidine nucleoside biosynthetic process	3.308432e-3
GO:0006545	glycine biosynthetic process	3.361590e-3
GO:0007569	cell aging	3.372438e-3
GO:0045082	positive regulation of interleukin-10 biosynthetic process	3.391459e-3
GO:0071392	cellular response to estradiol stimulus	3.458370e-3
GO:0034435	cholesterol esterification	3.462760e-3
GO:0034418	urate biosynthetic process	3.462760e-3
GO:0031427	response to methotrexate	3.462760e-3
GO:0007512	adult heart development	3.564264e-3
GO:0032269	negative regulation of cellular protein metabolic process	3.570033e-3
GO:0042428	serotonin metabolic process	3.571466e-3
GO:0034959	endothelin maturation	3.581611e-3
GO:0010816	calcitonin catabolic process	3.581611e-3
GO:0010814	substance P catabolic process	3.581611e-3
GO:0060071	Wnt receptor signaling pathway, planar cell polarity pathway	3.586919e-3
GO:2000209	regulation of anoikis	3.628346e-3
GO:0006313	transposition, DNA-mediated	3.674255e-3
GO:0001957	intramembranous ossification	3.706593e-3
GO:0060267	positive regulation of respiratory burst	3.723642e-3
GO:0001970	positive regulation of activation of membrane attack complex	3.723642e-3
GO:0043393	regulation of protein binding	3.733581e-3
GO:0030330	DNA damage response, signal transduction by p53 class mediator	3.741472e-3
GO:0035425	autocrine signaling	3.743667e-3
GO:0035356	cellular triglyceride homeostasis	3.743667e-3
GO:0010994	free ubiquitin chain polymerization	3.743667e-3
GO:0033092	positive regulation of immature T cell proliferation in thymus	3.779496e-3
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	3.799668e-3
GO:0048147	negative regulation of fibroblast proliferation	3.814117e-3
GO:0002756	MyD88-independent toll-like receptor signaling pathway	3.846868e-3
GO:0044332	Wnt receptor signaling pathway involved in dorsal/ventral axis specification	3.914790e-3
GO:0043103	hypoxanthine salvage	3.914790e-3
GO:0006110	regulation of glycolysis	3.953089e-3
GO:0019511	peptidyl-proline hydroxylation	3.957634e-3
GO:0006325	chromatin organization	3.976104e-3
GO:0001798	positive regulation of type IIa hypersensitivity	4.004855e-3
GO:0010717	regulation of epithelial to mesenchymal transition	4.041081e-3
GO:0009163	nucleoside biosynthetic process	4.090639e-3
GO:0060322	head development	4.160780e-3
GO:0060482	lobar bronchus development	4.204767e-3
GO:0009798	axis specification	4.207689e-3
GO:0045746	negative regulation of Notch signaling pathway	4.212364e-3
GO:0016575	histone deacetylation	4.280688e-3
GO:0033522	histone H2A ubiquitination	4.295577e-3
GO:0006544	glycine metabolic process	4.481803e-3
GO:0043174	nucleoside salvage	4.504863e-3
GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter	4.523772e-3
GO:0072363	regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter	4.523772e-3
GO:0090224	regulation of spindle organization	4.528163e-3
GO:0001941	postsynaptic membrane organization	4.537941e-3
GO:0043496	regulation of protein homodimerization activity	4.588112e-3
GO:0060711	labyrinthine layer development	4.602578e-3
GO:2000057	negative regulation of Wnt receptor signaling pathway involved in digestive tract morphogenesis	4.638109e-3
GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis	4.638109e-3
GO:0009822	alkaloid catabolic process	4.638109e-3
GO:0006529	asparagine biosynthetic process	4.638109e-3
GO:0006334	nucleosome assembly	4.689997e-3
GO:0060689	cell differentiation involved in salivary gland development	4.716921e-3
GO:0071504	cellular response to heparin	4.806966e-3
GO:0035566	regulation of metanephros size	4.836691e-3
GO:0006013	mannose metabolic process	4.911043e-3
GO:0008637	apoptotic mitochondrial changes	4.976563e-3
GO:0072132	mesenchyme morphogenesis	4.989527e-3
GO:0045136	development of secondary sexual characteristics	5.011624e-3
GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	5.060319e-3
GO:0022411	cellular component disassembly	5.122852e-3
GO:0046113	nucleobase catabolic process	5.149172e-3
GO:0032298	positive regulation of DNA-dependent DNA replication initiation	5.215241e-3
GO:0097037	heme export	5.215241e-3
GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway	5.215241e-3
GO:0006738	nicotinamide riboside catabolic process	5.215241e-3
GO:0006148	inosine catabolic process	5.215241e-3
GO:0043088	regulation of Cdc42 GTPase activity	5.253041e-3
GO:0071167	ribonucleoprotein complex import into nucleus	5.263127e-3
GO:0006780	uroporphyrinogen III biosynthetic process	5.263127e-3
GO:0030033	microvillus assembly	5.339341e-3
GO:0045299	otolith mineralization	5.382988e-3
GO:0010560	positive regulation of glycoprotein biosynthetic process	5.475152e-3
GO:0001510	RNA methylation	5.536793e-3
GO:0045918	negative regulation of cytolysis	5.559293e-3
GO:0021930	cerebellar granule cell precursor proliferation	5.569126e-3
GO:0045074	regulation of interleukin-10 biosynthetic process	5.570357e-3
GO:0046732	active induction of host immune response by virus	5.603700e-3
GO:0033033	negative regulation of myeloid cell apoptosis	5.621943e-3
GO:0002528	regulation of vascular permeability involved in acute inflammatory response	5.629514e-3
GO:0009298	GDP-mannose biosynthetic process	5.629514e-3
GO:0010718	positive regulation of epithelial to mesenchymal transition	5.756719e-3
GO:0060969	negative regulation of gene silencing	5.765889e-3
GO:0016926	protein desumoylation	5.829744e-3
GO:0042267	natural killer cell mediated cytotoxicity	5.926023e-3
GO:0000302	response to reactive oxygen species	5.989306e-3
GO:0043029	T cell homeostasis	6.077095e-3
GO:0035659	Wnt receptor signaling pathway involved in wound healing, spreading of epidermal cells	6.119012e-3
GO:0072303	positive regulation of glomerular metanephric mesangial cell proliferation	6.119012e-3
GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	6.119012e-3
GO:0009720	detection of hormone stimulus	6.119012e-3
GO:0014719	satellite cell activation	6.119012e-3
GO:0034436	glycoprotein transport	6.119012e-3
GO:0072331	signal transduction by p53 class mediator	6.143781e-3
GO:0071391	cellular response to estrogen stimulus	6.159832e-3
GO:0022617	extracellular matrix disassembly	6.274559e-3
GO:0070344	regulation of fat cell proliferation	6.324207e-3
GO:0035507	regulation of myosin-light-chain-phosphatase activity	6.402900e-3
GO:0007635	chemosensory behavior	6.433806e-3
GO:0060251	regulation of glial cell proliferation	6.495216e-3
GO:0031400	negative regulation of protein modification process	6.559862e-3
GO:0051443	positive regulation of ubiquitin-protein ligase activity	6.624842e-3
GO:0060456	positive regulation of digestive system process	6.653188e-3
GO:0007595	lactation	6.670832e-3
GO:0021782	glial cell development	6.774876e-3
GO:0060712	spongiotrophoblast layer development	6.782603e-3
GO:0006208	pyrimidine base catabolic process	6.902033e-3
GO:0090179	planar cell polarity pathway involved in neural tube closure	6.943527e-3
GO:0035623	renal glucose absorption	7.007762e-3
GO:0046038	GMP catabolic process	7.007762e-3
GO:0002522	leukocyte migration involved in immune response	7.007762e-3
GO:0006178	guanine salvage	7.007762e-3
GO:0000088	mitotic prophase	7.007762e-3
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	7.082058e-3
GO:0060690	epithelial cell differentiation involved in salivary gland development	7.122146e-3
GO:0003032	detection of oxygen	7.193260e-3
GO:0010889	regulation of sequestering of triglyceride	7.208096e-3
GO:0060441	epithelial tube branching involved in lung morphogenesis	7.248144e-3
GO:0071383	cellular response to steroid hormone stimulus	7.318504e-3
GO:0032223	negative regulation of synaptic transmission, cholinergic	7.361578e-3
GO:0045212	neurotransmitter receptor biosynthetic process	7.361578e-3
GO:0000414	regulation of histone H3-K36 methylation	7.366731e-3
GO:0002331	pre-B cell allelic exclusion	7.423028e-3
GO:0060324	face development	7.428381e-3
GO:0032792	negative regulation of CREB transcription factor activity	7.482306e-3
GO:0005978	glycogen biosynthetic process	7.725664e-3
GO:0001678	cellular glucose homeostasis	7.727691e-3
GO:0031936	negative regulation of chromatin silencing	7.754764e-3
GO:0090311	regulation of protein deacetylation	7.813542e-3
GO:0060707	trophoblast giant cell differentiation	7.847482e-3
GO:0043932	ossification involved in bone remodeling	7.863966e-3
GO:0051561	elevation of mitochondrial calcium ion concentration	7.875328e-3
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	7.987330e-3
GO:0031497	chromatin assembly	8.003811e-3
GO:0051126	negative regulation of actin nucleation	8.026852e-3
GO:0033314	mitotic cell cycle DNA replication checkpoint	8.026852e-3
GO:0032071	regulation of endodeoxyribonuclease activity	8.026852e-3
GO:0031929	TOR signaling cascade	8.027192e-3
GO:0031296	B cell costimulation	8.034436e-3
GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter	8.062826e-3
GO:0072300	positive regulation of metanephric glomerulus development	8.138773e-3
GO:0010629	negative regulation of gene expression	8.158931e-3
GO:0015816	glycine transport	8.343429e-3
GO:0042723	thiamine-containing compound metabolic process	8.343429e-3
GO:0010507	negative regulation of autophagy	8.343429e-3
GO:0001300	chronological cell aging	8.343429e-3
GO:0045906	negative regulation of vasoconstriction	8.362506e-3
GO:0030719	P granule organization	8.481473e-3
GO:0030488	tRNA methylation	8.481473e-3
GO:0042355	L-fucose catabolic process	8.500944e-3
GO:0051125	regulation of actin nucleation	8.552264e-3
GO:0046588	negative regulation of calcium-dependent cell-cell adhesion	8.552264e-3
GO:0070988	demethylation	8.596534e-3
GO:0033026	negative regulation of mast cell apoptosis	8.662751e-3
GO:0071229	cellular response to acid	8.694462e-3
GO:0048627	myoblast development	8.722268e-3
GO:0051154	negative regulation of striated muscle cell differentiation	8.726329e-3
GO:0000072	M phase specific microtubule process	8.810914e-3
GO:0060713	labyrinthine layer morphogenesis	8.904285e-3
GO:0046102	inosine metabolic process	8.979652e-3
GO:0043471	regulation of cellular carbohydrate catabolic process	9.035942e-3
GO:0060263	regulation of respiratory burst	9.127392e-3
GO:0009649	entrainment of circadian clock	9.135823e-3
GO:0008156	negative regulation of DNA replication	9.191865e-3
GO:0021696	cerebellar cortex morphogenesis	9.240340e-3
GO:0070668	positive regulation of mast cell proliferation	9.245973e-3
GO:0051261	protein depolymerization	9.348688e-3
GO:0016570	histone modification	9.374391e-3
GO:0010830	regulation of myotube differentiation	9.446400e-3
GO:0006972	hyperosmotic response	9.497784e-3
GO:0042093	T-helper cell differentiation	9.516571e-3
GO:0007422	peripheral nervous system development	9.605811e-3
GO:0097113	alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering	9.648545e-3
GO:2000143	negative regulation of transcription initiation, DNA-dependent	9.683717e-3
GO:0003406	retinal pigment epithelium development	9.683717e-3
GO:0071503	response to heparin	9.726021e-3
GO:0006476	protein deacetylation	9.739570e-3
GO:0072285	mesenchymal to epithelial transition involved in metanephric renal vesicle formation	9.799123e-3
GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway	9.799123e-3
GO:0007371	ventral midline determination	9.799123e-3
GO:0060816	random inactivation of X chromosome	9.799123e-3
GO:0060248	detection of cell density by contact stimulus involved in contact inhibition	9.799123e-3
GO:0045198	establishment of epithelial cell apical/basal polarity	9.997392e-3
GO:0035607	fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development	9.997392e-3
GO:0048489	synaptic vesicle transport	1.001527e-2
GO:0007023	post-chaperonin tubulin folding pathway	1.005527e-2
GO:0010626	negative regulation of Schwann cell proliferation	1.007089e-2
GO:2001014	regulation of skeletal muscle cell differentiation	1.011026e-2
GO:0071295	cellular response to vitamin	1.013608e-2
GO:0071845	cellular component disassembly at cellular level	1.027811e-2
GO:0070989	oxidative demethylation	1.036466e-2
GO:0002885	positive regulation of hypersensitivity	1.038549e-2
GO:0010523	negative regulation of calcium ion transport into cytosol	1.047940e-2
GO:0030208	dermatan sulfate biosynthetic process	1.048627e-2
GO:0008589	regulation of smoothened signaling pathway	1.056891e-2
GO:0014005	microglia development	1.060730e-2
GO:0070625	zymogen granule exocytosis	1.060730e-2
GO:0015931	nucleobase-containing compound transport	1.063071e-2
GO:0051041	positive regulation of calcium-independent cell-cell adhesion	1.065668e-2
GO:0050902	leukocyte adhesive activation	1.065668e-2
GO:0008595	anterior/posterior axis specification, embryo	1.067665e-2
GO:0042472	inner ear morphogenesis	1.072032e-2
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	1.078475e-2
GO:0030970	retrograde protein transport, ER to cytosol	1.078475e-2
GO:0046730	induction of host immune response by virus	1.081795e-2
GO:0031536	positive regulation of exit from mitosis	1.081795e-2
GO:0070904	transepithelial L-ascorbic acid transport	1.109421e-2
GO:0031167	rRNA methylation	1.112548e-2
GO:0033505	floor plate morphogenesis	1.112548e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0070647	protein modification by small protein conjugation or removal	7.525049e-17
GO:0016579	protein deubiquitination	3.124935e-12
GO:0016567	protein ubiquitination	1.651995e-10
GO:0070646	protein modification by small protein removal	6.729621e-10
GO:0002385	mucosal immune response	2.018633e-9
GO:0032446	protein modification by small protein conjugation	3.297098e-9
GO:0002251	organ or tissue specific immune response	8.340262e-9
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	9.954804e-9
GO:0002439	chronic inflammatory response to antigenic stimulus	1.535192e-8
GO:0006446	regulation of translational initiation	2.182688e-8
GO:0044240	multicellular organismal lipid catabolic process	3.125024e-8
GO:0002227	innate immune response in mucosa	3.193662e-8
GO:0006756	AMP phosphorylation	4.423721e-8
GO:0046034	ATP metabolic process	1.287595e-7
GO:0006482	protein demethylation	1.631031e-7
GO:0021591	ventricular system development	1.678971e-7
GO:0006982	response to lipid hydroperoxide	1.899492e-7
GO:0000910	cytokinesis	2.653867e-7
GO:0006287	base-excision repair, gap-filling	3.251706e-7
GO:0070527	platelet aggregation	3.994994e-7
GO:0070328	triglyceride homeostasis	4.652039e-7
GO:0010918	positive regulation of mitochondrial membrane potential	5.195932e-7
GO:0016577	histone demethylation	5.571427e-7
GO:0021670	lateral ventricle development	8.995672e-7
GO:0032239	regulation of nucleobase-containing compound transport	9.292576e-7
GO:0032534	regulation of microvillus assembly	9.340940e-7
GO:0044260	cellular macromolecule metabolic process	9.409057e-7
GO:0046940	nucleoside monophosphate phosphorylation	1.029706e-6
GO:2000078	positive regulation of type B pancreatic cell development	1.340050e-6
GO:0055009	atrial cardiac muscle tissue morphogenesis	1.594444e-6
GO:0046831	regulation of RNA export from nucleus	1.882091e-6
GO:0071316	cellular response to nicotine	2.034740e-6
GO:0000209	protein polyubiquitination	2.056720e-6
GO:0034728	nucleosome organization	2.141595e-6
GO:0045073	regulation of chemokine biosynthetic process	2.251710e-6
GO:0009259	ribonucleotide metabolic process	2.593014e-6
GO:0009141	nucleoside triphosphate metabolic process	2.649930e-6
GO:0006297	nucleotide-excision repair, DNA gap filling	2.906025e-6
GO:0061013	regulation of mRNA catabolic process	2.944806e-6
GO:0009051	pentose-phosphate shunt, oxidative branch	3.134255e-6
GO:0009205	purine ribonucleoside triphosphate metabolic process	3.312616e-6
GO:0009199	ribonucleoside triphosphate metabolic process	3.360585e-6
GO:0006334	nucleosome assembly	3.804389e-6
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	4.133045e-6
GO:0071157	negative regulation of cell cycle arrest	4.358866e-6
GO:0042559	pteridine-containing compound biosynthetic process	4.390947e-6
GO:0045080	positive regulation of chemokine biosynthetic process	4.794967e-6
GO:0006139	nucleobase-containing compound metabolic process	5.327522e-6
GO:0010898	positive regulation of triglyceride catabolic process	5.680675e-6
GO:0071526	semaphorin-plexin signaling pathway	6.578084e-6
GO:0055090	acylglycerol homeostasis	7.344461e-6
GO:0043654	recognition of apoptotic cell	7.344461e-6
GO:0009144	purine nucleoside triphosphate metabolic process	7.401505e-6
GO:0032615	interleukin-12 production	8.213992e-6
GO:0006333	chromatin assembly or disassembly	8.468906e-6
GO:0009150	purine ribonucleotide metabolic process	9.496548e-6
GO:0097022	lymphocyte migration into lymph node	1.029887e-5
GO:0072610	interleukin-12 secretion	1.029887e-5
GO:0009404	toxin metabolic process	1.056059e-5
GO:0032530	regulation of microvillus organization	1.070251e-5
GO:0021555	midbrain-hindbrain boundary morphogenesis	1.265924e-5
GO:0031914	negative regulation of synaptic plasticity	1.266723e-5
GO:0034641	cellular nitrogen compound metabolic process	1.420725e-5
GO:0070988	demethylation	1.439377e-5
GO:0034372	very-low-density lipoprotein particle remodeling	1.459349e-5
GO:0051301	cell division	1.545570e-5
GO:0031129	inductive cell-cell signaling	1.630690e-5
GO:0006807	nitrogen compound metabolic process	1.802031e-5
GO:0071824	protein-DNA complex subunit organization	1.907148e-5
GO:0035621	ER to Golgi ceramide transport	1.921259e-5
GO:0018230	peptidyl-L-cysteine S-palmitoylation	1.921259e-5
GO:0015747	urate transport	2.091171e-5
GO:0002675	positive regulation of acute inflammatory response	2.125592e-5
GO:0097026	dendritic cell dendrite assembly	2.144384e-5
GO:0046341	CDP-diacylglycerol metabolic process	2.144384e-5
GO:0060591	chondroblast differentiation	2.147764e-5
GO:0030048	actin filament-based movement	2.526460e-5
GO:0051298	centrosome duplication	2.627709e-5
GO:0006325	chromatin organization	3.124112e-5
GO:0033131	regulation of glucokinase activity	3.189566e-5
GO:0010890	positive regulation of sequestering of triglyceride	3.341541e-5
GO:0031440	regulation of mRNA 3'-end processing	3.426453e-5
GO:0021993	initiation of neural tube closure	3.498563e-5
GO:0044241	lipid digestion	4.862124e-5
GO:0032648	regulation of interferon-beta production	5.117350e-5
GO:0044267	cellular protein metabolic process	5.119349e-5
GO:0043303	mast cell degranulation	5.234270e-5
GO:0032479	regulation of type I interferon production	5.259367e-5
GO:0002275	myeloid cell activation involved in immune response	5.544373e-5
GO:0006163	purine nucleotide metabolic process	6.009450e-5
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	6.189153e-5
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	6.305934e-5
GO:0021528	commissural neuron differentiation in spinal cord	6.465123e-5
GO:0021678	third ventricle development	7.220792e-5
GO:0031349	positive regulation of defense response	7.259810e-5
GO:0031497	chromatin assembly	7.292298e-5
GO:0009117	nucleotide metabolic process	7.330951e-5
GO:0002642	positive regulation of immunoglobulin biosynthetic process	7.680563e-5
GO:0001768	establishment of T cell polarity	7.747416e-5
GO:0090042	tubulin deacetylation	8.544564e-5
GO:0030222	eosinophil differentiation	8.544564e-5
GO:0070846	Hsp90 deacetylation	8.544564e-5
GO:0019067	viral assembly, maturation, egress, and release	8.879526e-5
GO:0006464	protein modification process	9.575015e-5
GO:0051006	positive regulation of lipoprotein lipase activity	9.612778e-5
GO:0045723	positive regulation of fatty acid biosynthetic process	1.001986e-4
GO:0046483	heterocycle metabolic process	1.010257e-4
GO:0031442	positive regulation of mRNA 3'-end processing	1.031321e-4
GO:0033136	serine phosphorylation of STAT3 protein	1.034238e-4
GO:0042558	pteridine-containing compound metabolic process	1.129362e-4
GO:0008063	Toll signaling pathway	1.148902e-4
GO:0030878	thyroid gland development	1.294555e-4
GO:0006868	glutamine transport	1.353455e-4
GO:0065004	protein-DNA complex assembly	1.378958e-4
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	1.402631e-4
GO:0031115	negative regulation of microtubule polymerization	1.478832e-4
GO:0070634	transepithelial ammonium transport	1.493369e-4
GO:0021592	fourth ventricle development	1.493369e-4
GO:0002885	positive regulation of hypersensitivity	1.499470e-4
GO:0007049	cell cycle	1.538188e-4
GO:0034442	regulation of lipoprotein oxidation	1.546945e-4
GO:0055118	negative regulation of cardiac muscle contraction	1.647238e-4
GO:0003209	cardiac atrium morphogenesis	1.679259e-4
GO:0018130	heterocycle biosynthetic process	1.710410e-4
GO:0051443	positive regulation of ubiquitin-protein ligase activity	1.861640e-4
GO:0045624	positive regulation of T-helper cell differentiation	1.905489e-4
GO:0071474	cellular hyperosmotic response	1.972377e-4
GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development	2.011934e-4
GO:0090304	nucleic acid metabolic process	2.034879e-4
GO:0070302	regulation of stress-activated protein kinase signaling cascade	2.063002e-4
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	2.205345e-4
GO:0033504	floor plate development	2.224630e-4
GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	2.314985e-4
GO:0045064	T-helper 2 cell differentiation	2.381125e-4
GO:0090208	positive regulation of triglyceride metabolic process	2.475932e-4
GO:0006415	translational termination	2.592932e-4
GO:0015804	neutral amino acid transport	2.605097e-4
GO:0070076	histone lysine demethylation	2.697155e-4
GO:0015696	ammonium transport	2.717011e-4
GO:0050685	positive regulation of mRNA processing	2.723066e-4
GO:0031329	regulation of cellular catabolic process	2.769436e-4
GO:0007522	visceral muscle development	2.849781e-4
GO:0010870	positive regulation of receptor biosynthetic process	2.851217e-4
GO:0016584	nucleosome positioning	2.916575e-4
GO:0019359	nicotinamide nucleotide biosynthetic process	3.073404e-4
GO:0003341	cilium movement	3.107674e-4
GO:0043170	macromolecule metabolic process	3.132318e-4
GO:0010467	gene expression	3.196945e-4
GO:0090107	regulation of high-density lipoprotein particle assembly	3.227389e-4
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	3.227389e-4
GO:0014050	negative regulation of glutamate secretion	3.278725e-4
GO:0002649	regulation of tolerance induction to self antigen	3.278725e-4
GO:0044237	cellular metabolic process	3.324858e-4
GO:0009894	regulation of catabolic process	3.336428e-4
GO:0046929	negative regulation of neurotransmitter secretion	3.547884e-4
GO:0035435	phosphate ion transmembrane transport	3.547884e-4
GO:0006777	Mo-molybdopterin cofactor biosynthetic process	3.553738e-4
GO:0032796	uropod organization	3.562194e-4
GO:0046931	pore complex assembly	3.562194e-4
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	3.723786e-4
GO:0031331	positive regulation of cellular catabolic process	3.731716e-4
GO:0035584	calcium-mediated signaling using intracellular calcium source	3.752583e-4
GO:0045055	regulated secretory pathway	3.753383e-4
GO:0072393	microtubule anchoring at microtubule organizing center	3.796342e-4
GO:0006941	striated muscle contraction	3.797969e-4
GO:0046755	non-lytic virus budding	3.869717e-4
GO:0045226	extracellular polysaccharide biosynthetic process	3.869717e-4
GO:0007099	centriole replication	3.996620e-4
GO:0045988	negative regulation of striated muscle contraction	4.054220e-4
GO:0044243	multicellular organismal catabolic process	4.313108e-4
GO:0072521	purine-containing compound metabolic process	4.589241e-4
GO:0046328	regulation of JNK cascade	4.730149e-4
GO:0001771	immunological synapse formation	4.739694e-4
GO:0070544	histone H3-K36 demethylation	4.781283e-4
GO:0072522	purine-containing compound biosynthetic process	4.800089e-4
GO:0033205	cell cycle cytokinesis	4.917291e-4
GO:0048143	astrocyte activation	4.936353e-4
GO:0044342	type B pancreatic cell proliferation	5.001824e-4
GO:0031323	regulation of cellular metabolic process	5.009063e-4
GO:0060711	labyrinthine layer development	5.095310e-4
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	5.263976e-4
GO:0050892	intestinal absorption	5.277112e-4
GO:0009435	NAD biosynthetic process	5.343420e-4
GO:0051276	chromosome organization	5.483314e-4
GO:0051569	regulation of histone H3-K4 methylation	5.573637e-4
GO:0006914	autophagy	5.592580e-4
GO:0034370	triglyceride-rich lipoprotein particle remodeling	5.661063e-4
GO:0002758	innate immune response-activating signal transduction	5.854521e-4
GO:0023035	CD40 signaling pathway	5.882187e-4
GO:0072385	minus-end-directed organelle transport along microtubule	5.882187e-4
GO:0000725	recombinational repair	5.934050e-4
GO:0070633	transepithelial transport	5.965875e-4
GO:0015074	DNA integration	5.965875e-4
GO:0002518	lymphocyte chemotaxis across high endothelial venule	5.990912e-4
GO:2000412	positive regulation of thymocyte migration	5.990912e-4
GO:0006680	glucosylceramide catabolic process	6.067782e-4
GO:0033132	negative regulation of glucokinase activity	6.132098e-4
GO:0030505	inorganic diphosphate transport	6.132098e-4
GO:0045653	negative regulation of megakaryocyte differentiation	6.294486e-4
GO:0006657	CDP-choline pathway	6.294486e-4
GO:0072488	ammonium transmembrane transport	6.420509e-4
GO:0006491	N-glycan processing	6.453371e-4
GO:0050748	negative regulation of lipoprotein metabolic process	6.497036e-4
GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	6.740742e-4
GO:0043549	regulation of kinase activity	7.032557e-4
GO:0030730	sequestering of triglyceride	7.127277e-4
GO:0055119	relaxation of cardiac muscle	7.127277e-4
GO:0051438	regulation of ubiquitin-protein ligase activity	7.552339e-4
GO:0045796	negative regulation of intestinal cholesterol absorption	7.950939e-4
GO:0010949	negative regulation of intestinal phytosterol absorption	7.950939e-4
GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway	7.950939e-4
GO:0050862	positive regulation of T cell receptor signaling pathway	7.962712e-4
GO:0016236	macroautophagy	7.975161e-4
GO:0045579	positive regulation of B cell differentiation	7.992056e-4
GO:0090207	regulation of triglyceride metabolic process	8.036882e-4
GO:0010629	negative regulation of gene expression	8.062552e-4
GO:0071479	cellular response to ionizing radiation	8.128591e-4
GO:0006646	phosphatidylethanolamine biosynthetic process	8.217191e-4
GO:0061298	retina vasculature development in camera-type eye	8.217191e-4
GO:0035725	sodium ion transmembrane transport	8.327125e-4
GO:0072332	signal transduction by p53 class mediator resulting in induction of apoptosis	8.528776e-4
GO:0015808	L-alanine transport	8.542228e-4
GO:0010225	response to UV-C	8.671535e-4
GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly	8.736726e-4
GO:0070194	synaptonemal complex disassembly	8.736726e-4
GO:0045023	G0 to G1 transition	8.736726e-4
GO:0003273	cell migration involved in endocardial cushion formation	8.736726e-4
GO:0006164	purine nucleotide biosynthetic process	8.921620e-4
GO:0033133	positive regulation of glucokinase activity	8.990399e-4
GO:0042483	negative regulation of odontogenesis	9.234015e-4
GO:0090162	establishment of epithelial cell polarity	9.340482e-4
GO:0071383	cellular response to steroid hormone stimulus	9.380684e-4
GO:0003230	cardiac atrium development	9.476889e-4
GO:0043299	leukocyte degranulation	9.541973e-4
GO:0061046	regulation of branching involved in lung morphogenesis	9.578337e-4
GO:0051295	establishment of meiotic spindle localization	9.666105e-4
GO:0002036	regulation of L-glutamate transport	9.666105e-4
GO:0046881	positive regulation of follicle-stimulating hormone secretion	9.838251e-4
GO:0015793	glycerol transport	9.930218e-4
GO:2000286	receptor internalization involved in canonical Wnt receptor signaling pathway	9.930218e-4
GO:0045627	positive regulation of T-helper 1 cell differentiation	1.080824e-3
GO:0010457	centriole-centriole cohesion	1.126955e-3
GO:0009108	coenzyme biosynthetic process	1.139009e-3
GO:0061014	positive regulation of mRNA catabolic process	1.161663e-3
GO:0043412	macromolecule modification	1.194855e-3
GO:0070936	protein K48-linked ubiquitination	1.218877e-3
GO:0055088	lipid homeostasis	1.238676e-3
GO:0010725	regulation of primitive erythrocyte differentiation	1.243085e-3
GO:0009637	response to blue light	1.243085e-3
GO:0080090	regulation of primary metabolic process	1.274202e-3
GO:0046329	negative regulation of JNK cascade	1.286717e-3
GO:0033522	histone H2A ubiquitination	1.303062e-3
GO:2000178	negative regulation of neural precursor cell proliferation	1.306981e-3
GO:0030917	midbrain-hindbrain boundary development	1.314884e-3
GO:0043401	steroid hormone mediated signaling pathway	1.347210e-3
GO:0002678	positive regulation of chronic inflammatory response	1.395911e-3
GO:0060005	vestibular reflex	1.395911e-3
GO:0009987	cellular process	1.400270e-3
GO:0008286	insulin receptor signaling pathway	1.416461e-3
GO:0051092	positive regulation of NF-kappaB transcription factor activity	1.446375e-3
GO:0032926	negative regulation of activin receptor signaling pathway	1.475323e-3
GO:0042536	negative regulation of tumor necrosis factor biosynthetic process	1.475323e-3
GO:0007132	meiotic metaphase I	1.475323e-3
GO:0060370	susceptibility to T cell mediated cytotoxicity	1.494467e-3
GO:0006782	protoporphyrinogen IX biosynthetic process	1.494467e-3
GO:0055086	nucleobase-containing small molecule metabolic process	1.498792e-3
GO:0006359	regulation of transcription from RNA polymerase III promoter	1.508685e-3
GO:0010829	negative regulation of glucose transport	1.515095e-3
GO:0046325	negative regulation of glucose import	1.522826e-3
GO:0002883	regulation of hypersensitivity	1.526474e-3
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	1.529410e-3
GO:0032922	circadian regulation of gene expression	1.529410e-3
GO:0006754	ATP biosynthetic process	1.537512e-3
GO:0016070	RNA metabolic process	1.548875e-3
GO:0021965	spinal cord ventral commissure morphogenesis	1.563265e-3
GO:0002407	dendritic cell chemotaxis	1.587551e-3
GO:0007143	female meiosis	1.596356e-3
GO:0072331	signal transduction by p53 class mediator	1.598210e-3
GO:0070935	3'-UTR-mediated mRNA stabilization	1.600298e-3
GO:0045234	protein palmitoleylation	1.611057e-3
GO:0006948	induction by virus of host cell-cell fusion	1.611057e-3
GO:0060697	positive regulation of phospholipid catabolic process	1.612862e-3
GO:0009992	cellular water homeostasis	1.612862e-3
GO:0006707	cholesterol catabolic process	1.633446e-3
GO:2001022	positive regulation of response to DNA damage stimulus	1.641384e-3
GO:0009143	nucleoside triphosphate catabolic process	1.647465e-3
GO:0070979	protein K11-linked ubiquitination	1.656373e-3
GO:0045739	positive regulation of DNA repair	1.660040e-3
GO:0006863	purine base transport	1.684261e-3
GO:0022617	extracellular matrix disassembly	1.684261e-3
GO:0072595	maintenance of protein localization to organelle	1.761801e-3
GO:0032481	positive regulation of type I interferon production	1.774315e-3
GO:0002221	pattern recognition receptor signaling pathway	1.774315e-3
GO:0010896	regulation of triglyceride catabolic process	1.774315e-3
GO:0009755	hormone-mediated signaling pathway	1.798145e-3
GO:0042594	response to starvation	1.823261e-3
GO:0009152	purine ribonucleotide biosynthetic process	1.842819e-3
GO:0010830	regulation of myotube differentiation	1.870600e-3
GO:0050729	positive regulation of inflammatory response	1.927324e-3
GO:0030049	muscle filament sliding	2.022531e-3
GO:0044238	primary metabolic process	2.033073e-3
GO:0034645	cellular macromolecule biosynthetic process	2.056698e-3
GO:0033344	cholesterol efflux	2.091707e-3
GO:0022038	corpus callosum development	2.125214e-3
GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	2.187262e-3
GO:0032984	macromolecular complex disassembly	2.288968e-3
GO:0051894	positive regulation of focal adhesion assembly	2.308659e-3
GO:0051798	positive regulation of hair follicle development	2.308659e-3
GO:0000724	double-strand break repair via homologous recombination	2.332593e-3
GO:0002218	activation of innate immune response	2.338948e-3
GO:0090161	Golgi ribbon formation	2.377598e-3
GO:0051338	regulation of transferase activity	2.402872e-3
GO:0009261	ribonucleotide catabolic process	2.411007e-3
GO:0071478	cellular response to radiation	2.411149e-3
GO:0032971	regulation of muscle filament sliding	2.424423e-3
GO:0032241	positive regulation of nucleobase-containing compound transport	2.424423e-3
GO:0032513	negative regulation of protein phosphatase type 2B activity	2.424423e-3
GO:0032785	negative regulation of transcription elongation, DNA-dependent	2.430625e-3
GO:0045948	positive regulation of translational initiation	2.437178e-3
GO:0042990	regulation of transcription factor import into nucleus	2.446200e-3
GO:0033275	actin-myosin filament sliding	2.456298e-3
GO:0080135	regulation of cellular response to stress	2.458737e-3
GO:0006200	ATP catabolic process	2.483536e-3
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	2.494315e-3
GO:0007614	short-term memory	2.495287e-3
GO:0009267	cellular response to starvation	2.502240e-3
GO:0009207	purine ribonucleoside triphosphate catabolic process	2.544872e-3
GO:0001977	renal system process involved in regulation of blood volume	2.578942e-3
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	2.614822e-3
GO:0061048	negative regulation of branching involved in lung morphogenesis	2.628793e-3
GO:0045994	positive regulation of translational initiation by iron	2.628793e-3
GO:0002037	negative regulation of L-glutamate transport	2.628793e-3
GO:0034116	positive regulation of heterotypic cell-cell adhesion	2.628793e-3
GO:0032506	cytokinetic process	2.654132e-3
GO:0015816	glycine transport	2.654132e-3
GO:0003093	regulation of glomerular filtration	2.654132e-3
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	2.743899e-3
GO:0045859	regulation of protein kinase activity	2.751288e-3
GO:0010889	regulation of sequestering of triglyceride	2.771890e-3
GO:0048644	muscle organ morphogenesis	2.777156e-3
GO:0060644	mammary gland epithelial cell differentiation	2.791966e-3
GO:0046939	nucleotide phosphorylation	2.819633e-3
GO:0045945	positive regulation of transcription from RNA polymerase III promoter	2.846106e-3
GO:0006687	glycosphingolipid metabolic process	2.890144e-3
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	2.973482e-3
GO:0006927	transformed cell apoptosis	2.973482e-3
GO:0007168	receptor guanylyl cyclase signaling pathway	2.986987e-3
GO:0051253	negative regulation of RNA metabolic process	2.990007e-3
GO:0019438	aromatic compound biosynthetic process	2.992059e-3
GO:0034623	cellular macromolecular complex disassembly	3.038847e-3
GO:0031398	positive regulation of protein ubiquitination	3.069415e-3
GO:0042407	cristae formation	3.094574e-3
GO:0051353	positive regulation of oxidoreductase activity	3.108099e-3
GO:0015851	nucleobase transport	3.108652e-3
GO:0051090	regulation of sequence-specific DNA binding transcription factor activity	3.125318e-3
GO:0002074	extraocular skeletal muscle development	3.158493e-3
GO:0031076	embryonic camera-type eye development	3.173238e-3
GO:0006182	cGMP biosynthetic process	3.208070e-3
GO:0009059	macromolecule biosynthetic process	3.259177e-3
GO:0010558	negative regulation of macromolecule biosynthetic process	3.292986e-3
GO:0045947	negative regulation of translational initiation	3.306069e-3
GO:0006403	RNA localization	3.311154e-3
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	3.346153e-3
GO:0034976	response to endoplasmic reticulum stress	3.387697e-3
GO:0032507	maintenance of protein location in cell	3.391677e-3
GO:0019322	pentose biosynthetic process	3.426605e-3
GO:0008643	carbohydrate transport	3.443407e-3
GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter	3.450673e-3
GO:0009142	nucleoside triphosphate biosynthetic process	3.464021e-3
GO:0045089	positive regulation of innate immune response	3.475835e-3
GO:2000117	negative regulation of cysteine-type endopeptidase activity	3.506388e-3
GO:0009146	purine nucleoside triphosphate catabolic process	3.548099e-3
GO:0015824	proline transport	3.558459e-3
GO:0071900	regulation of protein serine/threonine kinase activity	3.562522e-3
GO:0071840	cellular component organization or biogenesis	3.576868e-3
GO:0009260	ribonucleotide biosynthetic process	3.605083e-3
GO:0007320	insemination	3.634440e-3
GO:0051764	actin crosslink formation	3.641569e-3
GO:0002426	immunoglobulin production in mucosal tissue	3.641569e-3
GO:0001829	trophectodermal cell differentiation	3.648030e-3
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	3.725437e-3
GO:0043088	regulation of Cdc42 GTPase activity	3.779942e-3
GO:0006706	steroid catabolic process	3.790914e-3
GO:0046415	urate metabolic process	3.836919e-3
GO:2000381	negative regulation of mesoderm development	3.839945e-3
GO:0009185	ribonucleoside diphosphate metabolic process	3.875625e-3
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	3.909806e-3
GO:0006406	mRNA export from nucleus	3.933607e-3
GO:0034612	response to tumor necrosis factor	3.991031e-3
GO:0045787	positive regulation of cell cycle	4.075228e-3
GO:0070252	actin-mediated cell contraction	4.088275e-3
GO:0021930	cerebellar granule cell precursor proliferation	4.124218e-3
GO:0019371	cyclooxygenase pathway	4.124218e-3
GO:0034384	high-density lipoprotein particle clearance	4.170681e-3
GO:0034446	substrate adhesion-dependent cell spreading	4.230761e-3
GO:0006983	ER overload response	4.248650e-3
GO:0071288	cellular response to mercury ion	4.286513e-3
GO:0070845	polyubiquitinated misfolded protein transport	4.286513e-3
GO:0070094	positive regulation of glucagon secretion	4.286513e-3
GO:0070561	vitamin D receptor signaling pathway	4.286513e-3
GO:0060578	superior vena cava morphogenesis	4.302672e-3
GO:0051351	positive regulation of ligase activity	4.433871e-3
GO:0038007	netrin-activated signaling pathway	4.452991e-3
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	4.534651e-3
GO:0046889	positive regulation of lipid biosynthetic process	4.536651e-3
GO:0050965	detection of temperature stimulus involved in sensory perception of pain	4.625989e-3
GO:0023021	termination of signal transduction	4.625989e-3
GO:0045185	maintenance of protein location	4.645789e-3
GO:0043691	reverse cholesterol transport	4.648445e-3
GO:0051235	maintenance of location	4.658873e-3
GO:2000781	positive regulation of double-strand break repair	4.708982e-3
GO:0030311	poly-N-acetyllactosamine biosynthetic process	4.708982e-3
GO:0045004	DNA replication proofreading	4.708982e-3
GO:0043610	regulation of carbohydrate utilization	4.708982e-3
GO:0032383	regulation of intracellular cholesterol transport	4.708982e-3
GO:0018208	peptidyl-proline modification	4.901051e-3
GO:0009314	response to radiation	4.939813e-3
GO:0060010	Sertoli cell fate commitment	5.029687e-3
GO:0044058	regulation of digestive system process	5.031756e-3
GO:0060415	muscle tissue morphogenesis	5.071838e-3
GO:0009145	purine nucleoside triphosphate biosynthetic process	5.108134e-3
GO:0016043	cellular component organization	5.132460e-3
GO:0000413	protein peptidyl-prolyl isomerization	5.161892e-3
GO:0051340	regulation of ligase activity	5.161892e-3
GO:0042771	DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis	5.168463e-3
GO:0045892	negative regulation of transcription, DNA-dependent	5.234730e-3
GO:0030259	lipid glycosylation	5.273908e-3
GO:0043981	histone H4-K5 acetylation	5.275075e-3
GO:0043982	histone H4-K8 acetylation	5.275075e-3
GO:0000281	cytokinesis after mitosis	5.275075e-3
GO:0000956	nuclear-transcribed mRNA catabolic process	5.286139e-3
GO:0051028	mRNA transport	5.342017e-3
GO:0031669	cellular response to nutrient levels	5.360775e-3
GO:0031060	regulation of histone methylation	5.462021e-3
GO:0009166	nucleotide catabolic process	5.469408e-3
GO:0071901	negative regulation of protein serine/threonine kinase activity	5.563693e-3
GO:0043407	negative regulation of MAP kinase activity	5.576199e-3
GO:0072321	chaperone-mediated protein transport	5.628764e-3
GO:0002030	inhibitory G-protein coupled receptor phosphorylation	5.628764e-3
GO:0001705	ectoderm formation	5.628764e-3
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	5.655143e-3
GO:0042035	regulation of cytokine biosynthetic process	5.699282e-3
GO:0018198	peptidyl-cysteine modification	5.773424e-3
GO:0009201	ribonucleoside triphosphate biosynthetic process	5.797545e-3
GO:0001574	ganglioside biosynthetic process	5.807118e-3
GO:0031668	cellular response to extracellular stimulus	5.891674e-3
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	6.079106e-3
GO:0048739	cardiac muscle fiber development	6.104976e-3
GO:0072239	metanephric glomerulus vasculature development	6.109412e-3
GO:0014002	astrocyte development	6.127108e-3
GO:0006688	glycosphingolipid biosynthetic process	6.142859e-3
GO:0060459	left lung development	6.144655e-3
GO:0015920	lipopolysaccharide transport	6.144655e-3
GO:0008633	activation of pro-apoptotic gene products	6.190880e-3
GO:0060685	regulation of prostatic bud formation	6.203825e-3
GO:0033146	regulation of estrogen receptor signaling pathway	6.203825e-3
GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process	6.217016e-3
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	6.217016e-3
GO:0009648	photoperiodism	6.217016e-3
GO:0006261	DNA-dependent DNA replication	6.267561e-3
GO:0006476	protein deacetylation	6.366504e-3
GO:0060075	regulation of resting membrane potential	6.370920e-3
GO:0048808	male genitalia morphogenesis	6.381930e-3
GO:0048313	Golgi inheritance	6.425925e-3
GO:0034369	plasma lipoprotein particle remodeling	6.492054e-3
GO:0051150	regulation of smooth muscle cell differentiation	6.558216e-3
GO:0044249	cellular biosynthetic process	6.594512e-3
GO:0060457	negative regulation of digestive system process	6.734808e-3
GO:0005978	glycogen biosynthetic process	6.745552e-3
GO:0072230	metanephric proximal straight tubule development	6.764330e-3
GO:0051458	corticotropin secretion	6.764330e-3
GO:0072232	metanephric proximal convoluted tubule segment 2 development	6.764330e-3
GO:0085018	maintenance of symbiont-containing vacuole via substance secreted by host	6.764330e-3
GO:0002368	B cell cytokine production	6.764330e-3
GO:0048291	isotype switching to IgG isotypes	6.764330e-3
GO:0072220	metanephric descending thin limb development	6.764330e-3
GO:0046833	positive regulation of RNA export from nucleus	6.764330e-3
GO:0002525	acute inflammatory response to non-antigenic stimulus	6.764330e-3
GO:0035378	carbon dioxide transmembrane transport	6.764330e-3
GO:0035377	transepithelial water transport	6.764330e-3
GO:0046670	positive regulation of retinal cell programmed cell death	6.764330e-3
GO:0007030	Golgi organization	6.768825e-3
GO:0006833	water transport	6.842340e-3
GO:0060558	regulation of calcidiol 1-monooxygenase activity	6.862593e-3
GO:0045622	regulation of T-helper cell differentiation	6.872887e-3
GO:0046902	regulation of mitochondrial membrane permeability	7.017927e-3
GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	7.017927e-3
GO:0006396	RNA processing	7.026148e-3
GO:2000383	regulation of ectoderm development	7.036104e-3
GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	7.036104e-3
GO:0071496	cellular response to external stimulus	7.049287e-3
GO:0002576	platelet degranulation	7.072239e-3
GO:0050927	positive regulation of positive chemotaxis	7.155439e-3
GO:0002224	toll-like receptor signaling pathway	7.262414e-3
GO:0032728	positive regulation of interferon-beta production	7.267575e-3
GO:0008624	induction of apoptosis by extracellular signals	7.270025e-3
GO:0042345	regulation of NF-kappaB import into nucleus	7.272970e-3
GO:0061036	positive regulation of cartilage development	7.323063e-3
GO:0002861	regulation of inflammatory response to antigenic stimulus	7.323063e-3
GO:0006678	glucosylceramide metabolic process	7.491288e-3