Novel motif:153

name:	motif153_ACTYNYYATYG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0000416	positive regulation of histone H3-K36 methylation	1.305673e-11
GO:0040040	thermosensory behavior	1.609082e-10
GO:0071460	cellular response to cell-matrix adhesion	4.110834e-10
GO:0050999	regulation of nitric-oxide synthase activity	5.433941e-10
GO:0030574	collagen catabolic process	6.698434e-10
GO:0009072	aromatic amino acid family metabolic process	2.056962e-9
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	2.634688e-9
GO:0045209	MAPK phosphatase export from nucleus, leptomycin B sensitive	3.978681e-9
GO:0045204	MAPK export from nucleus	3.978681e-9
GO:0051571	positive regulation of histone H3-K4 methylation	5.756454e-9
GO:0006663	platelet activating factor biosynthetic process	7.424557e-9
GO:0051649	establishment of localization in cell	8.456033e-9
GO:0090130	tissue migration	1.649475e-8
GO:0000414	regulation of histone H3-K36 methylation	2.944354e-8
GO:0010631	epithelial cell migration	3.390282e-8
GO:0030168	platelet activation	4.311490e-8
GO:0051641	cellular localization	9.461201e-8
GO:0051902	negative regulation of mitochondrial depolarization	1.071276e-7
GO:0046469	platelet activating factor metabolic process	1.251453e-7
GO:0046486	glycerolipid metabolic process	1.566699e-7
GO:0000278	mitotic cell cycle	2.429381e-7
GO:0051569	regulation of histone H3-K4 methylation	2.641638e-7
GO:0048661	positive regulation of smooth muscle cell proliferation	3.101245e-7
GO:0070189	kynurenine metabolic process	3.850242e-7
GO:0048294	negative regulation of isotype switching to IgE isotypes	4.095433e-7
GO:0006987	activation of signaling protein activity involved in unfolded protein response	6.281752e-7
GO:0000086	G2/M transition of mitotic cell cycle	6.360194e-7
GO:0051341	regulation of oxidoreductase activity	6.450695e-7
GO:0070625	zymogen granule exocytosis	6.594519e-7
GO:0006650	glycerophospholipid metabolic process	6.624029e-7
GO:2000685	positive regulation of cellular response to X-ray	8.224973e-7
GO:2001038	regulation of cellular response to drug	8.224973e-7
GO:2001033	negative regulation of double-strand break repair via nonhomologous end joining	8.224973e-7
GO:0035978	histone H2A-S139 phosphorylation	8.224973e-7
GO:0031052	chromosome breakage	8.224973e-7
GO:0003131	mesodermal-endodermal cell signaling	8.224973e-7
GO:0051900	regulation of mitochondrial depolarization	8.490478e-7
GO:0042158	lipoprotein biosynthetic process	1.057749e-6
GO:0019748	secondary metabolic process	1.135987e-6
GO:0042157	lipoprotein metabolic process	1.223934e-6
GO:0007093	mitotic cell cycle checkpoint	1.274008e-6
GO:0071404	cellular response to low-density lipoprotein particle stimulus	1.381326e-6
GO:0015696	ammonium transport	1.381326e-6
GO:0019441	tryptophan catabolic process to kynurenine	1.484479e-6
GO:0006582	melanin metabolic process	1.628151e-6
GO:0006497	protein lipidation	1.741250e-6
GO:0009607	response to biotic stimulus	1.747554e-6
GO:0045738	negative regulation of DNA repair	1.886507e-6
GO:0032768	regulation of monooxygenase activity	2.031222e-6
GO:0019087	transformation of host cell by virus	2.059083e-6
GO:0070885	negative regulation of calcineurin-NFAT signaling pathway	2.424220e-6
GO:0007052	mitotic spindle organization	2.550942e-6
GO:0006886	intracellular protein transport	2.920307e-6
GO:0051001	negative regulation of nitric-oxide synthase activity	2.977020e-6
GO:0001775	cell activation	3.020321e-6
GO:0071402	cellular response to lipoprotein particle stimulus	3.180265e-6
GO:0045910	negative regulation of DNA recombination	3.454551e-6
GO:0009617	response to bacterium	3.596738e-6
GO:0019439	aromatic compound catabolic process	4.038723e-6
GO:0046007	negative regulation of activated T cell proliferation	4.087014e-6
GO:0030573	bile acid catabolic process	4.633789e-6
GO:0014739	positive regulation of muscle hyperplasia	4.662779e-6
GO:0033962	cytoplasmic mRNA processing body assembly	4.715341e-6
GO:0001836	release of cytochrome c from mitochondria	4.797510e-6
GO:0006657	CDP-choline pathway	4.915124e-6
GO:0007265	Ras protein signal transduction	4.974521e-6
GO:0015808	L-alanine transport	4.989373e-6
GO:0016486	peptide hormone processing	5.166532e-6
GO:0043922	negative regulation by host of viral transcription	5.345491e-6
GO:0030004	cellular monovalent inorganic cation homeostasis	5.843817e-6
GO:0034374	low-density lipoprotein particle remodeling	5.910470e-6
GO:0071780	mitotic cell cycle G2/M transition checkpoint	6.276334e-6
GO:0009074	aromatic amino acid family catabolic process	6.340872e-6
GO:0008090	retrograde axon cargo transport	6.983509e-6
GO:0045851	pH reduction	7.296870e-6
GO:0044243	multicellular organismal catabolic process	7.390649e-6
GO:0072091	regulation of stem cell proliferation	7.492706e-6
GO:0051452	intracellular pH reduction	7.497946e-6
GO:0045759	negative regulation of action potential	7.747428e-6
GO:0007018	microtubule-based movement	7.876697e-6
GO:0045191	regulation of isotype switching	8.104163e-6
GO:0007095	mitotic cell cycle G2/M transition DNA damage checkpoint	8.302578e-6
GO:0032328	alanine transport	9.288083e-6
GO:0090398	cellular senescence	9.543251e-6
GO:0051298	centrosome duplication	9.758053e-6
GO:0060236	regulation of mitotic spindle organization	9.881096e-6
GO:0014074	response to purine-containing compound	1.000999e-5
GO:0010469	regulation of receptor activity	1.010953e-5
GO:0032409	regulation of transporter activity	1.033664e-5
GO:0071827	plasma lipoprotein particle organization	1.042263e-5
GO:0051707	response to other organism	1.050046e-5
GO:0048251	elastic fiber assembly	1.170447e-5
GO:0022402	cell cycle process	1.191451e-5
GO:0051329	interphase of mitotic cell cycle	1.204634e-5
GO:0090402	oncogene-induced senescence	1.205613e-5
GO:0045091	regulation of retroviral genome replication	1.387590e-5
GO:2000779	regulation of double-strand break repair	1.387590e-5
GO:0035988	chondrocyte proliferation	1.396340e-5
GO:0051702	interaction with symbiont	1.433590e-5
GO:0045869	negative regulation of retroviral genome replication	1.584738e-5
GO:0051255	spindle midzone assembly	1.618423e-5
GO:0015827	tryptophan transport	1.618423e-5
GO:0006569	tryptophan catabolic process	1.627547e-5
GO:0090307	spindle assembly involved in mitosis	1.714744e-5
GO:0051592	response to calcium ion	1.759315e-5
GO:0006568	tryptophan metabolic process	1.858097e-5
GO:0071615	oxidative deethylation	1.964077e-5
GO:0009403	toxin biosynthetic process	1.964077e-5
GO:0032958	inositol phosphate biosynthetic process	2.018096e-5
GO:0051482	elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger	2.019469e-5
GO:2000648	positive regulation of stem cell proliferation	2.029860e-5
GO:0006605	protein targeting	2.030685e-5
GO:0008088	axon cargo transport	2.052769e-5
GO:0051549	positive regulation of keratinocyte migration	2.111144e-5
GO:0022898	regulation of transmembrane transporter activity	2.160042e-5
GO:0034369	plasma lipoprotein particle remodeling	2.197127e-5
GO:0032412	regulation of ion transmembrane transporter activity	2.210374e-5
GO:0070997	neuron death	2.359666e-5
GO:0006586	indolalkylamine metabolic process	2.394551e-5
GO:0007067	mitosis	2.401078e-5
GO:0048293	regulation of isotype switching to IgE isotypes	2.408296e-5
GO:0085029	extracellular matrix assembly	2.412599e-5
GO:0032897	negative regulation of viral transcription	2.437157e-5
GO:2000602	regulation of interphase of mitotic cell cycle	2.540406e-5
GO:0032514	positive regulation of protein phosphatase type 2B activity	2.967030e-5
GO:0051402	neuron apoptosis	2.980874e-5
GO:0048599	oocyte development	3.000895e-5
GO:0002456	T cell mediated immunity	3.072904e-5
GO:0032075	positive regulation of nuclease activity	3.083739e-5
GO:0051325	interphase	3.159035e-5
GO:0035094	response to nicotine	3.215265e-5
GO:0030330	DNA damage response, signal transduction by p53 class mediator	3.269466e-5
GO:0060623	regulation of chromosome condensation	3.307377e-5
GO:0071283	cellular response to iron(III) ion	3.307377e-5
GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore	3.307377e-5
GO:0046680	response to DDT	3.307377e-5
GO:0046148	pigment biosynthetic process	3.353483e-5
GO:0042771	DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis	3.611585e-5
GO:0016572	histone phosphorylation	3.809358e-5
GO:0051497	negative regulation of stress fiber assembly	3.853267e-5
GO:0000087	M phase of mitotic cell cycle	4.058127e-5
GO:0031000	response to caffeine	4.119339e-5
GO:0046907	intracellular transport	4.412298e-5
GO:0022403	cell cycle phase	4.569468e-5
GO:0035966	response to topologically incorrect protein	4.606524e-5
GO:0009994	oocyte differentiation	4.958520e-5
GO:0042438	melanin biosynthetic process	5.066876e-5
GO:0007154	cell communication	5.178836e-5
GO:0050690	regulation of defense response to virus by virus	5.205486e-5
GO:0043921	modulation by host of viral transcription	5.297525e-5
GO:0031396	regulation of protein ubiquitination	5.514319e-5
GO:0051188	cofactor biosynthetic process	5.606687e-5
GO:0051453	regulation of intracellular pH	5.783380e-5
GO:0006282	regulation of DNA repair	5.978158e-5
GO:0010189	vitamin E biosynthetic process	6.279221e-5
GO:0071673	positive regulation of smooth muscle cell chemotaxis	6.364761e-5
GO:0042473	outer ear morphogenesis	6.376941e-5
GO:0002316	follicular B cell differentiation	6.511037e-5
GO:0042440	pigment metabolic process	6.804619e-5
GO:0045471	response to ethanol	7.140032e-5
GO:0051234	establishment of localization	7.194581e-5
GO:0034622	cellular macromolecular complex assembly	7.556503e-5
GO:0006878	cellular copper ion homeostasis	7.776152e-5
GO:0006508	proteolysis	7.784452e-5
GO:0032512	regulation of protein phosphatase type 2B activity	7.844737e-5
GO:0030277	maintenance of gastrointestinal epithelium	7.860690e-5
GO:0002576	platelet degranulation	7.923418e-5
GO:0048753	pigment granule organization	7.986544e-5
GO:0043623	cellular protein complex assembly	8.008423e-5
GO:0035986	senescence-associated heterochromatin focus formation	8.240176e-5
GO:2000774	positive regulation of cellular senescence	8.240176e-5
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	8.305004e-5
GO:0060282	positive regulation of oocyte development	8.330057e-5
GO:0046716	muscle cell homeostasis	8.332839e-5
GO:0051052	regulation of DNA metabolic process	8.522136e-5
GO:0010038	response to metal ion	8.531449e-5
GO:0032465	regulation of cytokinesis	9.033024e-5
GO:0003254	regulation of membrane depolarization	9.044238e-5
GO:0006950	response to stress	9.296232e-5
GO:0051256	spindle midzone assembly involved in mitosis	9.387098e-5
GO:0006868	glutamine transport	9.621848e-5
GO:0070482	response to oxygen levels	9.994021e-5
GO:2001022	positive regulation of response to DNA damage stimulus	1.046978e-4
GO:0002637	regulation of immunoglobulin production	1.057369e-4
GO:0048285	organelle fission	1.061821e-4
GO:0031576	G2/M transition checkpoint	1.066920e-4
GO:0030241	skeletal muscle myosin thick filament assembly	1.079044e-4
GO:0006338	chromatin remodeling	1.105716e-4
GO:0000077	DNA damage checkpoint	1.149381e-4
GO:0043691	reverse cholesterol transport	1.168701e-4
GO:0045110	intermediate filament bundle assembly	1.187180e-4
GO:0021680	cerebellar Purkinje cell layer development	1.193105e-4
GO:0030091	protein repair	1.218485e-4
GO:0031639	plasminogen activation	1.256977e-4
GO:0030003	cellular cation homeostasis	1.279337e-4
GO:0007098	centrosome cycle	1.321361e-4
GO:0032963	collagen metabolic process	1.408535e-4
GO:0050973	detection of mechanical stimulus involved in equilibrioception	1.448618e-4
GO:0006430	lysyl-tRNA aminoacylation	1.448618e-4
GO:0051272	positive regulation of cellular component movement	1.465966e-4
GO:0032411	positive regulation of transporter activity	1.532934e-4
GO:0051788	response to misfolded protein	1.569061e-4
GO:0043420	anthranilate metabolic process	1.594914e-4
GO:0034516	response to vitamin B6	1.594914e-4
GO:0048747	muscle fiber development	1.615684e-4
GO:0006434	seryl-tRNA aminoacylation	1.663267e-4
GO:0031507	heterochromatin formation	1.694734e-4
GO:0050871	positive regulation of B cell activation	1.699752e-4
GO:0060249	anatomical structure homeostasis	1.706003e-4
GO:0072331	signal transduction by p53 class mediator	1.706751e-4
GO:0046885	regulation of hormone biosynthetic process	1.724694e-4
GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	1.739885e-4
GO:0048660	regulation of smooth muscle cell proliferation	1.781128e-4
GO:0010669	epithelial structure maintenance	1.799553e-4
GO:0009628	response to abiotic stimulus	1.815749e-4
GO:0055070	copper ion homeostasis	1.817620e-4
GO:0043279	response to alkaloid	1.847181e-4
GO:0032496	response to lipopolysaccharide	1.912691e-4
GO:0035967	cellular response to topologically incorrect protein	1.941147e-4
GO:0043148	mitotic spindle stabilization	1.985272e-4
GO:0035026	leading edge cell differentiation	1.996458e-4
GO:0051084	'de novo' posttranslational protein folding	2.038385e-4
GO:0042360	vitamin E metabolic process	2.041321e-4
GO:0009108	coenzyme biosynthetic process	2.056776e-4
GO:0006979	response to oxidative stress	2.068274e-4
GO:0043968	histone H2A acetylation	2.086009e-4
GO:0010863	positive regulation of phospholipase C activity	2.097131e-4
GO:0006644	phospholipid metabolic process	2.217767e-4
GO:0051303	establishment of chromosome localization	2.250086e-4
GO:0001816	cytokine production	2.275621e-4
GO:0009312	oligosaccharide biosynthetic process	2.297469e-4
GO:0031959	mineralocorticoid receptor signaling pathway	2.317581e-4
GO:0055098	response to low-density lipoprotein particle stimulus	2.369870e-4
GO:0051704	multi-organism process	2.403172e-4
GO:0032769	negative regulation of monooxygenase activity	2.415299e-4
GO:0045793	positive regulation of cell size	2.417723e-4
GO:0009395	phospholipid catabolic process	2.450345e-4
GO:0007346	regulation of mitotic cell cycle	2.496738e-4
GO:0051179	localization	2.526314e-4
GO:0060281	regulation of oocyte development	2.544452e-4
GO:0019442	tryptophan catabolic process to acetyl-CoA	2.550265e-4
GO:0008203	cholesterol metabolic process	2.565861e-4
GO:0046689	response to mercury ion	2.580620e-4
GO:0035025	positive regulation of Rho protein signal transduction	2.590775e-4
GO:0019218	regulation of steroid metabolic process	2.607881e-4
GO:0006883	cellular sodium ion homeostasis	2.656016e-4
GO:0008637	apoptotic mitochondrial changes	2.689077e-4
GO:0032414	positive regulation of ion transmembrane transporter activity	2.690472e-4
GO:0000296	spermine transport	2.760624e-4
GO:0031570	DNA integrity checkpoint	2.794898e-4
GO:0023052	signaling	2.828451e-4
GO:0034063	stress granule assembly	2.841469e-4
GO:0030641	regulation of cellular pH	2.931252e-4
GO:0009611	response to wounding	2.941053e-4
GO:0006810	transport	3.016081e-4
GO:0018874	benzoate metabolic process	3.185511e-4
GO:0009311	oligosaccharide metabolic process	3.198551e-4
GO:0033124	regulation of GTP catabolic process	3.355176e-4
GO:0043438	acetoacetic acid metabolic process	3.454873e-4
GO:0002829	negative regulation of type 2 immune response	3.515389e-4
GO:0045143	homologous chromosome segregation	3.791555e-4
GO:0060033	anatomical structure regression	3.871583e-4
GO:0006629	lipid metabolic process	3.916247e-4
GO:0009408	response to heat	3.920391e-4
GO:0006458	'de novo' protein folding	3.923617e-4
GO:0044259	multicellular organismal macromolecule metabolic process	3.926692e-4
GO:0022037	metencephalon development	4.015205e-4
GO:0007596	blood coagulation	4.036144e-4
GO:0055001	muscle cell development	4.076160e-4
GO:0010212	response to ionizing radiation	4.095156e-4
GO:0006706	steroid catabolic process	4.148939e-4
GO:0035404	histone-serine phosphorylation	4.169365e-4
GO:0016139	glycoside catabolic process	4.384595e-4
GO:0009314	response to radiation	4.391677e-4
GO:0034621	cellular macromolecular complex subunit organization	4.417900e-4
GO:0002237	response to molecule of bacterial origin	4.495058e-4
GO:0030335	positive regulation of cell migration	4.542967e-4
GO:0019538	protein metabolic process	4.591353e-4
GO:0040001	establishment of mitotic spindle localization	4.609003e-4
GO:0010810	regulation of cell-substrate adhesion	4.635745e-4
GO:0006612	protein targeting to membrane	4.732322e-4
GO:0051053	negative regulation of DNA metabolic process	4.838149e-4
GO:0006814	sodium ion transport	4.861159e-4
GO:0007599	hemostasis	4.905959e-4
GO:0031958	corticosteroid receptor signaling pathway	4.992676e-4
GO:0001953	negative regulation of cell-matrix adhesion	5.013425e-4
GO:0044255	cellular lipid metabolic process	5.042094e-4
GO:0030719	P granule organization	5.133649e-4
GO:0034103	regulation of tissue remodeling	5.147207e-4
GO:0006196	AMP catabolic process	5.218558e-4
GO:0035582	negative regulation of BMP signaling pathway by extracellular sequestering of BMP	5.232512e-4
GO:0046496	nicotinamide nucleotide metabolic process	5.269499e-4
GO:0001952	regulation of cell-matrix adhesion	5.347598e-4
GO:0030225	macrophage differentiation	5.360340e-4
GO:0050777	negative regulation of immune response	5.413306e-4
GO:0071731	response to nitric oxide	5.672650e-4
GO:0032236	positive regulation of calcium ion transport via store-operated calcium channel activity	5.672650e-4
GO:0000018	regulation of DNA recombination	5.674321e-4
GO:0045017	glycerolipid biosynthetic process	5.740333e-4
GO:0033160	positive regulation of protein import into nucleus, translocation	6.141661e-4
GO:0070159	mitochondrial threonyl-tRNA aminoacylation	6.211688e-4
GO:0016142	O-glycoside catabolic process	6.211688e-4
GO:0001666	response to hypoxia	6.222363e-4
GO:2000147	positive regulation of cell motility	6.236298e-4
GO:0031572	G2/M transition DNA damage checkpoint	6.267795e-4
GO:0051146	striated muscle cell differentiation	6.294471e-4
GO:0019674	NAD metabolic process	6.303811e-4
GO:0055067	monovalent inorganic cation homeostasis	6.349675e-4
GO:0051716	cellular response to stimulus	6.367727e-4
GO:0007049	cell cycle	6.413124e-4
GO:0000279	M phase	6.416560e-4
GO:0015804	neutral amino acid transport	6.470023e-4
GO:0009629	response to gravity	6.492514e-4
GO:0007017	microtubule-based process	6.543005e-4
GO:0050864	regulation of B cell activation	6.614332e-4
GO:0002768	immune response-regulating cell surface receptor signaling pathway	6.797962e-4
GO:0003161	cardiac conduction system development	6.815083e-4
GO:0031398	positive regulation of protein ubiquitination	6.821228e-4
GO:0065009	regulation of molecular function	6.826532e-4
GO:0034976	response to endoplasmic reticulum stress	7.102080e-4
GO:0019725	cellular homeostasis	7.199370e-4
GO:0043497	regulation of protein heterodimerization activity	7.289233e-4
GO:0016601	Rac protein signal transduction	7.318895e-4
GO:0007202	activation of phospholipase C activity	7.350104e-4
GO:0033059	cellular pigmentation	7.351736e-4
GO:0019637	organophosphate metabolic process	7.523726e-4
GO:0070989	oxidative demethylation	7.578870e-4
GO:2000021	regulation of ion homeostasis	7.612186e-4
GO:0017038	protein import	7.623467e-4
GO:0051384	response to glucocorticoid stimulus	7.628212e-4
GO:0010288	response to lead ion	7.673799e-4
GO:0050810	regulation of steroid biosynthetic process	7.718984e-4
GO:0051345	positive regulation of hydrolase activity	7.765006e-4
GO:0033864	positive regulation of NAD(P)H oxidase activity	7.852033e-4
GO:0046477	glycosylceramide catabolic process	7.879748e-4
GO:0072332	signal transduction by p53 class mediator resulting in induction of apoptosis	7.890861e-4
GO:0006413	translational initiation	8.006736e-4
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	8.229545e-4
GO:0009435	NAD biosynthetic process	8.278857e-4
GO:0019229	regulation of vasoconstriction	8.338043e-4
GO:0019438	aromatic compound biosynthetic process	8.352514e-4
GO:0035928	rRNA import into mitochondrion	8.407750e-4
GO:0051856	adhesion to symbiont	8.450901e-4
GO:0032026	response to magnesium ion	8.560700e-4
GO:0046688	response to copper ion	8.644206e-4
GO:0055094	response to lipoprotein stimulus	8.681588e-4
GO:0060427	lung connective tissue development	8.701370e-4
GO:0030011	maintenance of cell polarity	8.781189e-4
GO:2000683	regulation of cellular response to X-ray	8.836938e-4
GO:0051984	positive regulation of chromosome segregation	9.028588e-4
GO:0002457	T cell antigen processing and presentation	9.028588e-4
GO:0010477	response to sulfur dioxide	9.028588e-4
GO:0051276	chromosome organization	9.067664e-4
GO:0014070	response to organic cyclic compound	9.105797e-4
GO:0051851	modification by host of symbiont morphology or physiology	9.172997e-4
GO:0008608	attachment of spindle microtubules to kinetochore	9.309617e-4
GO:0032413	negative regulation of ion transmembrane transporter activity	9.506294e-4
GO:0061098	positive regulation of protein tyrosine kinase activity	9.690229e-4
GO:0033261	regulation of S phase	9.913655e-4
GO:0090343	positive regulation of cell aging	9.979109e-4
GO:0048477	oogenesis	9.992570e-4
GO:0045069	regulation of viral genome replication	1.004685e-3
GO:0045428	regulation of nitric oxide biosynthetic process	1.008824e-3
GO:0042427	serotonin biosynthetic process	1.010516e-3
GO:0044093	positive regulation of molecular function	1.016379e-3
GO:0031329	regulation of cellular catabolic process	1.026497e-3
GO:0033126	positive regulation of GTP catabolic process	1.028923e-3
GO:0010035	response to inorganic substance	1.049851e-3
GO:0019363	pyridine nucleotide biosynthetic process	1.056068e-3
GO:0006707	cholesterol catabolic process	1.062820e-3
GO:0018130	heterocycle biosynthetic process	1.076889e-3
GO:0060409	positive regulation of acetylcholine metabolic process	1.105372e-3
GO:0035987	endodermal cell differentiation	1.108455e-3
GO:0050878	regulation of body fluid levels	1.111660e-3
GO:0019362	pyridine nucleotide metabolic process	1.130329e-3
GO:0071888	macrophage apoptosis	1.136772e-3
GO:0042218	1-aminocyclopropane-1-carboxylate biosynthetic process	1.145952e-3
GO:0033591	response to L-ascorbic acid	1.172937e-3
GO:0030301	cholesterol transport	1.173740e-3
GO:0032237	activation of store-operated calcium channel activity	1.175037e-3
GO:0000075	cell cycle checkpoint	1.175665e-3
GO:0031023	microtubule organizing center organization	1.193815e-3
GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint	1.196458e-3
GO:0033004	negative regulation of mast cell activation	1.203399e-3
GO:0042759	long-chain fatty acid biosynthetic process	1.215811e-3
GO:0060193	positive regulation of lipase activity	1.220234e-3
GO:0051258	protein polymerization	1.241492e-3
GO:0045040	protein import into mitochondrial outer membrane	1.245994e-3
GO:0055093	response to hyperoxia	1.247909e-3
GO:0015031	protein transport	1.250074e-3
GO:0010518	positive regulation of phospholipase activity	1.252812e-3
GO:0051169	nuclear transport	1.264459e-3
GO:0046474	glycerophospholipid biosynthetic process	1.277870e-3
GO:0018076	N-terminal peptidyl-lysine acetylation	1.295471e-3
GO:0035024	negative regulation of Rho protein signal transduction	1.307294e-3
GO:0023019	signal transduction involved in regulation of gene expression	1.314517e-3
GO:0071671	regulation of smooth muscle cell chemotaxis	1.314836e-3
GO:0034613	cellular protein localization	1.331756e-3
GO:0061097	regulation of protein tyrosine kinase activity	1.339304e-3
GO:0050911	detection of chemical stimulus involved in sensory perception of smell	1.342151e-3
GO:0032959	inositol trisphosphate biosynthetic process	1.348494e-3
GO:0019605	butyrate metabolic process	1.348494e-3
GO:0071674	mononuclear cell migration	1.354826e-3
GO:0002018	renin-angiotensin regulation of aldosterone production	1.354826e-3
GO:0045900	negative regulation of translational elongation	1.354826e-3
GO:0019359	nicotinamide nucleotide biosynthetic process	1.367660e-3
GO:0006873	cellular ion homeostasis	1.378079e-3
GO:0016125	sterol metabolic process	1.390552e-3
GO:0045907	positive regulation of vasoconstriction	1.393406e-3
GO:0071732	cellular response to nitric oxide	1.399442e-3
GO:0008089	anterograde axon cargo transport	1.399442e-3
GO:0042058	regulation of epidermal growth factor receptor signaling pathway	1.423922e-3
GO:0032232	negative regulation of actin filament bundle assembly	1.433925e-3
GO:0007156	homophilic cell adhesion	1.441942e-3
GO:0048739	cardiac muscle fiber development	1.446747e-3
GO:0032700	negative regulation of interleukin-17 production	1.457546e-3
GO:0048669	collateral sprouting in absence of injury	1.460181e-3
GO:0015801	aromatic amino acid transport	1.478432e-3
GO:0006913	nucleocytoplasmic transport	1.483575e-3
GO:0051209	release of sequestered calcium ion into cytosol	1.486199e-3
GO:0043547	positive regulation of GTPase activity	1.488866e-3
GO:0046473	phosphatidic acid metabolic process	1.495237e-3
GO:0048671	negative regulation of collateral sprouting	1.512369e-3
GO:0042559	pteridine-containing compound biosynthetic process	1.537769e-3
GO:0060298	positive regulation of sarcomere organization	1.542827e-3
GO:0022600	digestive system process	1.543416e-3
GO:0007623	circadian rhythm	1.561948e-3
GO:0016485	protein processing	1.567979e-3
GO:0071158	positive regulation of cell cycle arrest	1.597086e-3
GO:0021549	cerebellum development	1.604232e-3
GO:0035583	negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta	1.607302e-3
GO:0061136	regulation of proteasomal protein catabolic process	1.612602e-3
GO:0033693	neurofilament bundle assembly	1.640867e-3
GO:0032438	melanosome organization	1.644442e-3
GO:0046886	positive regulation of hormone biosynthetic process	1.651304e-3
GO:0006911	phagocytosis, engulfment	1.653779e-3
GO:0048583	regulation of response to stimulus	1.660750e-3
GO:0055078	sodium ion homeostasis	1.666674e-3
GO:0060191	regulation of lipase activity	1.690681e-3
GO:0008610	lipid biosynthetic process	1.695182e-3
GO:0070727	cellular macromolecule localization	1.713092e-3
GO:0021589	cerebellum structural organization	1.714534e-3
GO:0060904	regulation of protein folding in endoplasmic reticulum	1.714534e-3
GO:0001787	natural killer cell proliferation	1.714534e-3
GO:0051365	cellular response to potassium ion starvation	1.726516e-3
GO:0055002	striated muscle cell development	1.780381e-3
GO:0045124	regulation of bone resorption	1.787421e-3
GO:0070884	regulation of calcineurin-NFAT signaling pathway	1.808963e-3
GO:0001556	oocyte maturation	1.820873e-3
GO:0051604	protein maturation	1.836445e-3
GO:0046470	phosphatidylcholine metabolic process	1.839271e-3
GO:0006325	chromatin organization	1.854699e-3
GO:0023035	CD40 signaling pathway	1.865538e-3
GO:0046629	gamma-delta T cell activation	1.865538e-3
GO:0019068	virion assembly	1.865538e-3
GO:0006457	protein folding	1.882230e-3
GO:0031062	positive regulation of histone methylation	1.883386e-3
GO:0032069	regulation of nuclease activity	1.897009e-3
GO:0042439	ethanolamine-containing compound metabolic process	1.899865e-3
GO:0015918	sterol transport	1.938875e-3
GO:0015851	nucleobase transport	1.947300e-3
GO:0097006	regulation of plasma lipoprotein particle levels	1.948910e-3
GO:0006725	cellular aromatic compound metabolic process	1.970654e-3
GO:0021575	hindbrain morphogenesis	1.971394e-3
GO:0009169	purine ribonucleoside monophosphate catabolic process	1.975121e-3
GO:0032350	regulation of hormone metabolic process	2.015043e-3
GO:0009125	nucleoside monophosphate catabolic process	2.042661e-3
GO:0042742	defense response to bacterium	2.114619e-3
GO:0051282	regulation of sequestering of calcium ion	2.115844e-3
GO:0051297	centrosome organization	2.141929e-3
GO:0032320	positive regulation of Ras GTPase activity	2.150749e-3
GO:0051492	regulation of stress fiber assembly	2.162899e-3
GO:0050849	negative regulation of calcium-mediated signaling	2.195395e-3
GO:0042542	response to hydrogen peroxide	2.196284e-3
GO:0006639	acylglycerol metabolic process	2.251260e-3
GO:0002683	negative regulation of immune system process	2.257639e-3
GO:0061049	cell growth involved in cardiac muscle cell development	2.265809e-3
GO:0014873	response to muscle activity involved in regulation of muscle adaptation	2.265809e-3
GO:0003331	positive regulation of extracellular matrix constituent secretion	2.265809e-3
GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure	2.265809e-3
GO:0046949	fatty-acyl-CoA biosynthetic process	2.266352e-3
GO:0051354	negative regulation of oxidoreductase activity	2.297723e-3
GO:0033121	regulation of purine nucleotide catabolic process	2.305676e-3
GO:0040017	positive regulation of locomotion	2.314809e-3
GO:0016569	covalent chromatin modification	2.364210e-3
GO:0006699	bile acid biosynthetic process	2.391262e-3
GO:0006930	substrate-dependent cell migration, cell extension	2.392226e-3
GO:0021860	pyramidal neuron development	2.396568e-3
GO:0016137	glycoside metabolic process	2.396568e-3
GO:0048743	positive regulation of skeletal muscle fiber development	2.415712e-3
GO:0006641	triglyceride metabolic process	2.427325e-3
GO:0071453	cellular response to oxygen levels	2.444897e-3
GO:0030968	endoplasmic reticulum unfolded protein response	2.487317e-3
GO:0043950	positive regulation of cAMP-mediated signaling	2.548247e-3
GO:0018095	protein polyglutamylation	2.548247e-3
GO:0043117	positive regulation of vascular permeability	2.553619e-3
GO:0071777	positive regulation of cell cycle cytokinesis	2.581448e-3
GO:0002577	regulation of antigen processing and presentation	2.589843e-3
GO:0045723	positive regulation of fatty acid biosynthetic process	2.600612e-3
GO:0048096	chromatin-mediated maintenance of transcription	2.600612e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0018924	mandelate metabolic process	1.358381e-12
GO:0006436	tryptophanyl-tRNA aminoacylation	1.862096e-9
GO:0003012	muscle system process	7.784918e-8
GO:0018094	protein polyglycylation	1.134680e-7
GO:0002252	immune effector process	1.157029e-7
GO:0006955	immune response	1.440164e-7
GO:0000059	protein import into nucleus, docking	2.070374e-7
GO:0042938	dipeptide transport	2.759982e-7
GO:0001682	tRNA 5'-leader removal	4.230784e-7
GO:0016078	tRNA catabolic process	4.230784e-7
GO:0006556	S-adenosylmethionine biosynthetic process	9.516867e-7
GO:0090310	negative regulation of methylation-dependent chromatin silencing	1.120668e-6
GO:0009236	cobalamin biosynthetic process	1.434746e-6
GO:0005980	glycogen catabolic process	1.586307e-6
GO:0043032	positive regulation of macrophage activation	2.241779e-6
GO:0002443	leukocyte mediated immunity	4.587349e-6
GO:0034661	ncRNA catabolic process	4.595416e-6
GO:0006936	muscle contraction	5.971611e-6
GO:0045815	positive regulation of gene expression, epigenetic	7.810170e-6
GO:0006707	cholesterol catabolic process	7.810170e-6
GO:0051384	response to glucocorticoid stimulus	7.848885e-6
GO:0031394	positive regulation of prostaglandin biosynthetic process	8.594224e-6
GO:0070365	hepatocyte differentiation	9.388051e-6
GO:0007494	midgut development	1.038576e-5
GO:0006857	oligopeptide transport	1.238117e-5
GO:0031960	response to corticosteroid stimulus	1.676085e-5
GO:0042891	antibiotic transport	2.001282e-5
GO:0009235	cobalamin metabolic process	2.001282e-5
GO:0032092	positive regulation of protein binding	2.382504e-5
GO:0001812	positive regulation of type I hypersensitivity	2.689651e-5
GO:0043030	regulation of macrophage activation	2.717027e-5
GO:0002561	basophil degranulation	2.751402e-5
GO:0002502	peptide antigen assembly with MHC class I protein complex	2.751402e-5
GO:0051099	positive regulation of binding	2.838514e-5
GO:0006669	sphinganine-1-phosphate biosynthetic process	3.419585e-5
GO:0010842	retina layer formation	3.430735e-5
GO:0006959	humoral immune response	3.726168e-5
GO:0051443	positive regulation of ubiquitin-protein ligase activity	5.056806e-5
GO:0042271	susceptibility to natural killer cell mediated cytotoxicity	5.549939e-5
GO:0006956	complement activation	5.990589e-5
GO:0006603	phosphocreatine metabolic process	6.003443e-5
GO:0044238	primary metabolic process	6.007437e-5
GO:0045575	basophil activation	6.228639e-5
GO:0032057	negative regulation of translational initiation in response to stress	7.279859e-5
GO:0021985	neurohypophysis development	7.279859e-5
GO:0031936	negative regulation of chromatin silencing	7.476022e-5
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	7.771628e-5
GO:0007109	cytokinesis, completion of separation	8.243188e-5
GO:0019098	reproductive behavior	8.651296e-5
GO:0006730	one-carbon metabolic process	9.057545e-5
GO:0043170	macromolecule metabolic process	9.062009e-5
GO:0060338	regulation of type I interferon-mediated signaling pathway	9.614827e-5
GO:0045717	negative regulation of fatty acid biosynthetic process	9.681592e-5
GO:0072376	protein activation cascade	1.084666e-4
GO:0045226	extracellular polysaccharide biosynthetic process	1.097453e-4
GO:0034113	heterotypic cell-cell adhesion	1.143056e-4
GO:0060968	regulation of gene silencing	1.143056e-4
GO:0019538	protein metabolic process	1.206983e-4
GO:0019882	antigen processing and presentation	1.207967e-4
GO:0006668	sphinganine-1-phosphate metabolic process	1.208308e-4
GO:0060969	negative regulation of gene silencing	1.210407e-4
GO:0002891	positive regulation of immunoglobulin mediated immune response	1.214147e-4
GO:0006304	DNA modification	1.303834e-4
GO:0000272	polysaccharide catabolic process	1.379420e-4
GO:0031935	regulation of chromatin silencing	1.409853e-4
GO:0002250	adaptive immune response	1.465600e-4
GO:0001810	regulation of type I hypersensitivity	1.496929e-4
GO:0001805	positive regulation of type III hypersensitivity	1.496929e-4
GO:0006957	complement activation, alternative pathway	1.571339e-4
GO:0048048	embryonic eye morphogenesis	1.585664e-4
GO:0046314	phosphocreatine biosynthetic process	1.595394e-4
GO:0021979	hypothalamus cell differentiation	1.595394e-4
GO:0002541	activation of plasma proteins involved in acute inflammatory response	1.595394e-4
GO:0046599	regulation of centriole replication	1.701173e-4
GO:0006909	phagocytosis	1.713591e-4
GO:0090037	positive regulation of protein kinase C signaling cascade	1.891550e-4
GO:0046784	intronless viral mRNA export from host nucleus	1.909988e-4
GO:0033692	cellular polysaccharide biosynthetic process	1.921635e-4
GO:0001915	negative regulation of T cell mediated cytotoxicity	1.974882e-4
GO:0002449	lymphocyte mediated immunity	2.322240e-4
GO:0045588	positive regulation of gamma-delta T cell differentiation	2.365970e-4
GO:0002444	myeloid leukocyte mediated immunity	2.394860e-4
GO:0006367	transcription initiation from RNA polymerase II promoter	2.705435e-4
GO:0051607	defense response to virus	2.827807e-4
GO:0006949	syncytium formation	2.867754e-4
GO:0033120	positive regulation of RNA splicing	2.954599e-4
GO:0071360	cellular response to exogenous dsRNA	3.027167e-4
GO:0048596	embryonic camera-type eye morphogenesis	3.079481e-4
GO:0001788	antibody-dependent cellular cytotoxicity	3.088053e-4
GO:0007618	mating	3.114202e-4
GO:0045321	leukocyte activation	3.128707e-4
GO:0006399	tRNA metabolic process	3.209241e-4
GO:0050855	regulation of B cell receptor signaling pathway	3.210909e-4
GO:0046500	S-adenosylmethionine metabolic process	3.280233e-4
GO:0034637	cellular carbohydrate biosynthetic process	3.502703e-4
GO:0060206	estrous cycle phase	3.535767e-4
GO:0006694	steroid biosynthetic process	3.551646e-4
GO:0043248	proteasome assembly	3.719607e-4
GO:0001775	cell activation	3.817039e-4
GO:0035510	DNA dealkylation	4.022546e-4
GO:0000165	MAPKKK cascade	4.065780e-4
GO:0030157	pancreatic juice secretion	4.219838e-4
GO:0032259	methylation	4.235486e-4
GO:0000920	cytokinetic cell separation	4.337031e-4
GO:0051209	release of sequestered calcium ion into cytosol	4.362497e-4
GO:0032689	negative regulation of interferon-gamma production	4.369240e-4
GO:0042304	regulation of fatty acid biosynthetic process	4.456514e-4
GO:0070375	BMK cascade	4.613702e-4
GO:0002699	positive regulation of immune effector process	4.653054e-4
GO:0002697	regulation of immune effector process	4.802375e-4
GO:0000018	regulation of DNA recombination	4.895237e-4
GO:0032674	regulation of interleukin-5 production	4.914630e-4
GO:0048239	negative regulation of DNA recombination at telomere	4.929825e-4
GO:0006430	lysyl-tRNA aminoacylation	4.929825e-4
GO:0007094	mitotic cell cycle spindle assembly checkpoint	4.995214e-4
GO:0060010	Sertoli cell fate commitment	5.032916e-4
GO:0045793	positive regulation of cell size	5.386705e-4
GO:0008299	isoprenoid biosynthetic process	5.388189e-4
GO:0046963	3'-phosphoadenosine 5'-phosphosulfate transport	5.451498e-4
GO:0000768	syncytium formation by plasma membrane fusion	5.616703e-4
GO:0071174	mitotic cell cycle spindle checkpoint	5.731978e-4
GO:0045922	negative regulation of fatty acid metabolic process	6.094285e-4
GO:0048388	endosomal lumen acidification	6.146070e-4
GO:0030518	steroid hormone receptor signaling pathway	6.238622e-4
GO:0060402	calcium ion transport into cytosol	6.367722e-4
GO:0006937	regulation of muscle contraction	6.388177e-4
GO:0046129	purine ribonucleoside biosynthetic process	6.740693e-4
GO:0021869	forebrain ventricular zone progenitor cell division	6.771785e-4
GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	7.440915e-4
GO:0061072	iris morphogenesis	7.453786e-4
GO:0042628	mating plug formation	7.453786e-4
GO:0031034	myosin filament assembly	7.453786e-4
GO:0044275	cellular carbohydrate catabolic process	7.477966e-4
GO:0016126	sterol biosynthetic process	7.615671e-4
GO:0001938	positive regulation of endothelial cell proliferation	7.841915e-4
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	8.021355e-4
GO:0055069	zinc ion homeostasis	8.051893e-4
GO:0060297	regulation of sarcomere organization	8.673640e-4
GO:0006706	steroid catabolic process	8.903592e-4
GO:0019724	B cell mediated immunity	8.925036e-4
GO:0045541	negative regulation of cholesterol biosynthetic process	8.936719e-4
GO:0032816	positive regulation of natural killer cell activation	8.981932e-4
GO:0014889	muscle atrophy	9.332124e-4
GO:0051351	positive regulation of ligase activity	9.556239e-4
GO:0072428	signal transduction involved in intra-S DNA damage checkpoint	9.584509e-4
GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	9.789718e-4
GO:0007621	negative regulation of female receptivity	1.001103e-3
GO:0007520	myoblast fusion	1.057567e-3
GO:0051055	negative regulation of lipid biosynthetic process	1.151151e-3
GO:0060401	cytosolic calcium ion transport	1.159942e-3
GO:0034660	ncRNA metabolic process	1.179777e-3
GO:0051823	regulation of synapse structural plasticity	1.220409e-3
GO:0046631	alpha-beta T cell activation	1.225691e-3
GO:0002762	negative regulation of myeloid leukocyte differentiation	1.256669e-3
GO:0010767	regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage	1.261244e-3
GO:0015808	L-alanine transport	1.261244e-3
GO:0051282	regulation of sequestering of calcium ion	1.310047e-3
GO:0045062	extrathymic T cell selection	1.321148e-3
GO:0010900	negative regulation of phosphatidylcholine catabolic process	1.321148e-3
GO:0016064	immunoglobulin mediated immune response	1.324679e-3
GO:0050847	progesterone receptor signaling pathway	1.382414e-3
GO:0048304	positive regulation of isotype switching to IgG isotypes	1.384737e-3
GO:0002708	positive regulation of lymphocyte mediated immunity	1.395879e-3
GO:0030318	melanocyte differentiation	1.396292e-3
GO:0001959	regulation of cytokine-mediated signaling pathway	1.406422e-3
GO:0006575	cellular modified amino acid metabolic process	1.432078e-3
GO:0048002	antigen processing and presentation of peptide antigen	1.455763e-3
GO:0048384	retinoic acid receptor signaling pathway	1.470237e-3
GO:0031444	slow-twitch skeletal muscle fiber contraction	1.483489e-3
GO:0005978	glycogen biosynthetic process	1.502823e-3
GO:0032781	positive regulation of ATPase activity	1.513549e-3
GO:0009110	vitamin biosynthetic process	1.528581e-3
GO:0032656	regulation of interleukin-13 production	1.528581e-3
GO:0070509	calcium ion import	1.530350e-3
GO:0016074	snoRNA metabolic process	1.530350e-3
GO:0001842	neural fold formation	1.530350e-3
GO:0015966	diadenosine tetraphosphate biosynthetic process	1.630574e-3
GO:0030890	positive regulation of B cell proliferation	1.679805e-3
GO:0060759	regulation of response to cytokine stimulus	1.702819e-3
GO:0001826	inner cell mass cell differentiation	1.715985e-3
GO:0002761	regulation of myeloid leukocyte differentiation	1.718559e-3
GO:0060298	positive regulation of sarcomere organization	1.734323e-3
GO:0050931	pigment cell differentiation	1.792958e-3
GO:0046605	regulation of centrosome cycle	1.800480e-3
GO:0007320	insemination	1.818885e-3
GO:0032506	cytokinetic process	1.906855e-3
GO:0060409	positive regulation of acetylcholine metabolic process	1.909801e-3
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	1.909801e-3
GO:0008152	metabolic process	1.939604e-3
GO:0030825	positive regulation of cGMP metabolic process	1.978787e-3
GO:0071625	vocalization behavior	1.978787e-3
GO:0061350	planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	2.016038e-3
GO:0061349	planar cell polarity pathway involved in cardiac right atrium morphogenesis	2.016038e-3
GO:0061354	planar cell polarity pathway involved in pericardium morphogenesis	2.016038e-3
GO:0060210	metestrus	2.016038e-3
GO:0061347	planar cell polarity pathway involved in outflow tract morphogenesis	2.016038e-3
GO:0061348	planar cell polarity pathway involved in ventricular septum morphogenesis	2.016038e-3
GO:0006975	DNA damage induced protein phosphorylation	2.066871e-3
GO:0006401	RNA catabolic process	2.079996e-3
GO:0031341	regulation of cell killing	2.094944e-3
GO:2000821	regulation of grooming behavior	2.102979e-3
GO:0040032	post-embryonic body morphogenesis	2.118624e-3
GO:0031343	positive regulation of cell killing	2.207331e-3
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	2.231778e-3
GO:0006520	cellular amino acid metabolic process	2.293498e-3
GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	2.330975e-3
GO:0032696	negative regulation of interleukin-13 production	2.332554e-3
GO:0031338	regulation of vesicle fusion	2.332554e-3
GO:0071173	spindle assembly checkpoint	2.348436e-3
GO:0016052	carbohydrate catabolic process	2.391702e-3
GO:0071391	cellular response to estrogen stimulus	2.411479e-3
GO:0015959	diadenosine polyphosphate metabolic process	2.471432e-3
GO:0034589	hydroxyproline transport	2.471432e-3
GO:0015826	threonine transport	2.471432e-3
GO:0006931	substrate-dependent cell migration, cell attachment to substrate	2.471432e-3
GO:0002369	T cell cytokine production	2.473084e-3
GO:0043558	regulation of translational initiation in response to stress	2.480909e-3
GO:0001910	regulation of leukocyte mediated cytotoxicity	2.486224e-3
GO:0002702	positive regulation of production of molecular mediator of immune response	2.508490e-3
GO:0051412	response to corticosterone stimulus	2.511821e-3
GO:0007243	intracellular protein kinase cascade	2.532687e-3
GO:0006508	proteolysis	2.569136e-3
GO:0001912	positive regulation of leukocyte mediated cytotoxicity	2.580882e-3
GO:0019511	peptidyl-proline hydroxylation	2.597323e-3
GO:0043500	muscle adaptation	2.618793e-3
GO:0001911	negative regulation of leukocyte mediated cytotoxicity	2.618793e-3
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	2.692775e-3
GO:0035329	hippo signaling cascade	2.692775e-3
GO:0031347	regulation of defense response	2.718030e-3
GO:0031342	negative regulation of cell killing	2.743974e-3
GO:0002440	production of molecular mediator of immune response	2.809228e-3
GO:0015825	L-serine transport	2.951955e-3
GO:0006531	aspartate metabolic process	2.951955e-3
GO:0002710	negative regulation of T cell mediated immunity	3.036078e-3
GO:0032713	negative regulation of interleukin-4 production	3.041257e-3
GO:0060067	cervix development	3.070120e-3
GO:0060340	positive regulation of type I interferon-mediated signaling pathway	3.105106e-3
GO:0048026	positive regulation of nuclear mRNA splicing, via spliceosome	3.105106e-3
GO:0031642	negative regulation of myelination	3.136856e-3
GO:0042364	water-soluble vitamin biosynthetic process	3.171952e-3
GO:0045947	negative regulation of translational initiation	3.171952e-3
GO:0001936	regulation of endothelial cell proliferation	3.204619e-3
GO:0035914	skeletal muscle cell differentiation	3.223460e-3
GO:0010569	regulation of double-strand break repair via homologous recombination	3.463970e-3
GO:0031340	positive regulation of vesicle fusion	3.469130e-3
GO:0021905	forebrain-midbrain boundary formation	3.484273e-3
GO:0021918	regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment	3.484273e-3
GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	3.484273e-3
GO:0006106	fumarate metabolic process	3.484273e-3
GO:0003322	pancreatic A cell development	3.484273e-3
GO:0001757	somite specification	3.484273e-3
GO:0045630	positive regulation of T-helper 2 cell differentiation	3.499217e-3
GO:0015879	carnitine transport	3.499217e-3
GO:0016556	mRNA modification	3.499217e-3
GO:2000822	regulation of behavioral fear response	3.545607e-3
GO:0002478	antigen processing and presentation of exogenous peptide antigen	3.604314e-3
GO:0090281	negative regulation of calcium ion import	3.699053e-3
GO:0071584	negative regulation of zinc ion import	3.699053e-3
GO:0080009	mRNA methylation	3.699053e-3
GO:0002720	positive regulation of cytokine production involved in immune response	3.767365e-3
GO:0030852	regulation of granulocyte differentiation	3.795424e-3
GO:0010824	regulation of centrosome duplication	3.847400e-3
GO:0001866	NK T cell proliferation	3.853538e-3
GO:0021903	rostrocaudal neural tube patterning	3.877121e-3
GO:0051382	kinetochore assembly	3.914694e-3
GO:0055007	cardiac muscle cell differentiation	3.955496e-3
GO:0032328	alanine transport	3.971303e-3
GO:0060599	lateral sprouting involved in mammary gland duct morphogenesis	3.971303e-3
GO:0002741	positive regulation of cytokine secretion involved in immune response	3.971303e-3
GO:0000731	DNA synthesis involved in DNA repair	3.971303e-3
GO:0001961	positive regulation of cytokine-mediated signaling pathway	3.988140e-3
GO:0045621	positive regulation of lymphocyte differentiation	4.017459e-3
GO:0014044	Schwann cell development	4.074336e-3
GO:0050803	regulation of synapse structure and activity	4.140643e-3
GO:0045765	regulation of angiogenesis	4.157909e-3
GO:0042398	cellular modified amino acid biosynthetic process	4.164345e-3
GO:0031577	spindle checkpoint	4.165678e-3
GO:0006396	RNA processing	4.198172e-3
GO:0002673	regulation of acute inflammatory response	4.249721e-3
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	4.275440e-3
GO:0030865	cortical cytoskeleton organization	4.469102e-3
GO:0006352	transcription initiation, DNA-dependent	4.487950e-3
GO:0022011	myelination in peripheral nervous system	4.519333e-3
GO:0032375	negative regulation of cholesterol transport	4.560935e-3
GO:0008033	tRNA processing	4.600700e-3
GO:0045214	sarcomere organization	4.689934e-3
GO:0002700	regulation of production of molecular mediator of immune response	4.699165e-3
GO:0045065	cytotoxic T cell differentiation	4.731324e-3
GO:0021506	anterior neuropore closure	4.731324e-3
GO:0030888	regulation of B cell proliferation	4.785335e-3
GO:0043950	positive regulation of cAMP-mediated signaling	4.813239e-3
GO:0061037	negative regulation of cartilage development	4.874562e-3
GO:0001798	positive regulation of type IIa hypersensitivity	4.874562e-3
GO:0090257	regulation of muscle system process	5.006799e-3
GO:0002344	B cell affinity maturation	5.054468e-3
GO:0032814	regulation of natural killer cell activation	5.087620e-3
GO:0048313	Golgi inheritance	5.138057e-3
GO:0002551	mast cell chemotaxis	5.138057e-3
GO:0003416	endochondral bone growth	5.171907e-3
GO:0050776	regulation of immune response	5.210554e-3
GO:0060350	endochondral bone morphogenesis	5.249772e-3
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	5.406429e-3
GO:0032055	negative regulation of translation in response to stress	5.491274e-3
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	5.491274e-3
GO:0045087	innate immune response	5.547105e-3
GO:0031076	embryonic camera-type eye development	5.768375e-3
GO:0015811	L-cystine transport	5.840410e-3
GO:0046633	alpha-beta T cell proliferation	5.876975e-3
GO:0080111	DNA demethylation	5.876975e-3
GO:0043949	regulation of cAMP-mediated signaling	5.876975e-3
GO:0002456	T cell mediated immunity	5.996550e-3
GO:0007617	mating behavior	6.035847e-3
GO:0060760	positive regulation of response to cytokine stimulus	6.046393e-3
GO:0031018	endocrine pancreas development	6.047473e-3
GO:0060907	positive regulation of macrophage cytokine production	6.179846e-3
GO:0003008	system process	6.259853e-3
GO:0042396	phosphagen biosynthetic process	6.310888e-3
GO:0048850	hypophysis morphogenesis	6.339720e-3
GO:0002831	regulation of response to biotic stimulus	6.343397e-3
GO:0032819	positive regulation of natural killer cell proliferation	6.377998e-3
GO:0030239	myofibril assembly	6.484294e-3
GO:0002521	leukocyte differentiation	6.530799e-3
GO:0046514	ceramide catabolic process	6.560927e-3
GO:0051385	response to mineralocorticoid stimulus	6.592848e-3
GO:0014902	myotube differentiation	6.700635e-3
GO:0006091	generation of precursor metabolites and energy	6.728510e-3
GO:0043623	cellular protein complex assembly	6.748092e-3
GO:0015909	long-chain fatty acid transport	6.775153e-3
GO:0071585	detoxification of cadmium ion	6.869622e-3
GO:0003105	negative regulation of glomerular filtration	6.869622e-3
GO:0060215	primitive hemopoiesis	6.890474e-3
GO:0032714	negative regulation of interleukin-5 production	6.890474e-3
GO:0033239	negative regulation of cellular amine metabolic process	6.928069e-3
GO:0044264	cellular polysaccharide metabolic process	6.937494e-3
GO:0006952	defense response	6.950067e-3
GO:0030970	retrograde protein transport, ER to cytosol	7.003715e-3
GO:0060591	chondroblast differentiation	7.064398e-3
GO:0032329	serine transport	7.212610e-3
GO:0043414	macromolecule methylation	7.253259e-3
GO:0051146	striated muscle cell differentiation	7.282363e-3
GO:0003417	growth plate cartilage development	7.345314e-3
GO:0046649	lymphocyte activation	7.546631e-3
GO:0048646	anatomical structure formation involved in morphogenesis	7.565008e-3
GO:0002274	myeloid leukocyte activation	7.719235e-3
GO:0032649	regulation of interferon-gamma production	7.972400e-3
GO:0008037	cell recognition	8.033132e-3
GO:0048302	regulation of isotype switching to IgG isotypes	8.053712e-3
GO:0021796	cerebral cortex regionalization	8.200390e-3
GO:0009913	epidermal cell differentiation	8.216043e-3
GO:0014732	skeletal muscle atrophy	8.273920e-3
GO:0048066	developmental pigmentation	8.287827e-3
GO:0051383	kinetochore organization	8.310215e-3
GO:0046929	negative regulation of neurotransmitter secretion	8.310215e-3
GO:0030217	T cell differentiation	8.421222e-3
GO:0009988	cell-cell recognition	8.666024e-3
GO:0002238	response to molecule of fungal origin	8.711149e-3
GO:0002920	regulation of humoral immune response	8.792816e-3
GO:0030520	estrogen receptor signaling pathway	8.810778e-3
GO:0030224	monocyte differentiation	8.833728e-3
GO:0042921	glucocorticoid receptor signaling pathway	8.849726e-3
GO:0002706	regulation of lymphocyte mediated immunity	8.904914e-3
GO:0000722	telomere maintenance via recombination	8.906926e-3
GO:0008202	steroid metabolic process	8.909985e-3
GO:0008284	positive regulation of cell proliferation	8.990148e-3
GO:0072236	metanephric loop of Henle development	9.014606e-3
GO:0048706	embryonic skeletal system development	9.017109e-3
GO:0030853	negative regulation of granulocyte differentiation	9.259424e-3
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	9.409191e-3
GO:0010038	response to metal ion	9.454256e-3
GO:0031573	intra-S DNA damage checkpoint	9.596326e-3
GO:0014823	response to activity	9.684605e-3
GO:0032673	regulation of interleukin-4 production	9.735321e-3
GO:0051964	negative regulation of synapse assembly	9.802693e-3
GO:0071407	cellular response to organic cyclic compound	9.982263e-3
GO:0006418	tRNA aminoacylation for protein translation	1.007400e-2
GO:0001778	plasma membrane repair	1.009224e-2
GO:0051168	nuclear export	1.024591e-2
GO:0045104	intermediate filament cytoskeleton organization	1.035189e-2
GO:0016051	carbohydrate biosynthetic process	1.039931e-2
GO:0032970	regulation of actin filament-based process	1.042401e-2
GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification	1.044936e-2
GO:0045292	nuclear mRNA cis splicing, via spliceosome	1.056768e-2
GO:0007620	copulation	1.057936e-2
GO:0048562	embryonic organ morphogenesis	1.060025e-2
GO:0060696	regulation of phospholipid catabolic process	1.063984e-2
GO:0034260	negative regulation of GTPase activity	1.063984e-2
GO:0030162	regulation of proteolysis	1.100531e-2
GO:0042403	thyroid hormone metabolic process	1.110113e-2
GO:0042176	regulation of protein catabolic process	1.111176e-2
GO:0031032	actomyosin structure organization	1.113684e-2
GO:0001819	positive regulation of cytokine production	1.122652e-2
GO:0055012	ventricular cardiac muscle cell differentiation	1.151649e-2
GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	1.152337e-2
GO:0051961	negative regulation of nervous system development	1.152768e-2
GO:0045830	positive regulation of isotype switching	1.156683e-2
GO:2000484	positive regulation of interleukin-8 secretion	1.160666e-2
GO:0003344	pericardium morphogenesis	1.160666e-2
GO:0034384	high-density lipoprotein particle clearance	1.162934e-2
GO:0050871	positive regulation of B cell activation	1.187204e-2
GO:0051005	negative regulation of lipoprotein lipase activity	1.196286e-2
GO:0007052	mitotic spindle organization	1.196286e-2
GO:0035051	cardiac cell differentiation	1.216320e-2
GO:0019884	antigen processing and presentation of exogenous antigen	1.229779e-2
GO:0045833	negative regulation of lipid metabolic process	1.245176e-2
GO:0045924	regulation of female receptivity	1.246785e-2
GO:0002367	cytokine production involved in immune response	1.246785e-2
GO:0071295	cellular response to vitamin	1.256077e-2
GO:0045576	mast cell activation	1.262446e-2
GO:0048096	chromatin-mediated maintenance of transcription	1.271555e-2
GO:0009584	detection of visible light	1.272213e-2
GO:0034605	cellular response to heat	1.275713e-2
GO:0046632	alpha-beta T cell differentiation	1.285192e-2
GO:0051216	cartilage development	1.290861e-2
GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness	1.295189e-2
GO:0072054	renal outer medulla development	1.308700e-2
GO:0010922	positive regulation of phosphatase activity	1.310762e-2
GO:0003056	regulation of vascular smooth muscle contraction	1.315237e-2
GO:0061088	regulation of sequestering of zinc ion	1.315237e-2
GO:0000395	nuclear mRNA 5'-splice site recognition	1.315237e-2
GO:0006939	smooth muscle contraction	1.319392e-2
GO:0060059	embryonic retina morphogenesis in camera-type eye	1.327035e-2
GO:0045103	intermediate filament-based process	1.342079e-2
GO:0034447	very-low-density lipoprotein particle clearance	1.346193e-2
GO:0030866	cortical actin cytoskeleton organization	1.357279e-2
GO:0009066	aspartate family amino acid metabolic process	1.358428e-2
GO:0071222	cellular response to lipopolysaccharide	1.380030e-2
GO:0032805	positive regulation of low-density lipoprotein particle receptor catabolic process	1.393782e-2
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	1.393782e-2
GO:0006406	mRNA export from nucleus	1.412891e-2
GO:0043631	RNA polyadenylation	1.424444e-2
GO:0021797	forebrain anterior/posterior pattern specification	1.424858e-2
GO:0070198	protein localization to chromosome, telomeric region	1.456007e-2
GO:0030050	vesicle transport along actin filament	1.456007e-2
GO:0060192	negative regulation of lipase activity	1.484197e-2
GO:0002889	regulation of immunoglobulin mediated immune response	1.484700e-2
GO:0090304	nucleic acid metabolic process	1.492511e-2
GO:0072061	inner medullary collecting duct development	1.509263e-2
GO:0072060	outer medullary collecting duct development	1.509263e-2
GO:0043049	otic placode formation	1.509263e-2
GO:0016332	establishment or maintenance of polarity of embryonic epithelium	1.509263e-2
GO:0006474	N-terminal protein amino acid acetylation	1.515199e-2
GO:0000187	activation of MAPK activity	1.517320e-2
GO:0032956	regulation of actin cytoskeleton organization	1.534896e-2
GO:0031123	RNA 3'-end processing	1.538490e-2
GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.560302e-2
GO:0003306	Wnt receptor signaling pathway involved in heart development	1.561812e-2
GO:0042063	gliogenesis	1.575892e-2
GO:0042098	T cell proliferation	1.576387e-2
GO:0001525	angiogenesis	1.595406e-2
GO:0045637	regulation of myeloid cell differentiation	1.603023e-2
GO:0030212	hyaluronan metabolic process	1.612049e-2
GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification	1.614020e-2
GO:0009086	methionine biosynthetic process	1.621757e-2
GO:0007015	actin filament organization	1.622541e-2
GO:0030522	intracellular receptor mediated signaling pathway	1.629628e-2
GO:0006479	protein methylation	1.632803e-2
GO:0071072	negative regulation of phospholipid biosynthetic process	1.648381e-2
GO:0045599	negative regulation of fat cell differentiation	1.666363e-2
GO:0042100	B cell proliferation	1.672883e-2
GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress	1.685386e-2
GO:0097107	postsynaptic density assembly	1.694482e-2
GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	1.694482e-2
GO:0015798	myo-inositol transport	1.694482e-2
GO:0050853	B cell receptor signaling pathway	1.698694e-2
GO:0042404	thyroid hormone catabolic process	1.706493e-2
GO:0006910	phagocytosis, recognition	1.716973e-2
GO:0043402	glucocorticoid mediated signaling pathway	1.720405e-2
GO:0044111	development involved in symbiotic interaction	1.720405e-2
GO:0019089	transmission of virus	1.720405e-2
GO:0010768	negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage	1.720405e-2
GO:2000021	regulation of ion homeostasis	1.720882e-2
GO:0045191	regulation of isotype switching	1.726186e-2
GO:0002674	negative regulation of acute inflammatory response	1.727237e-2
GO:0006405	RNA export from nucleus	1.733716e-2
GO:0009119	ribonucleoside metabolic process	1.744956e-2
GO:0050766	positive regulation of phagocytosis	1.746742e-2
GO:2000727	positive regulation of cardiac muscle cell differentiation	1.751359e-2
GO:0071216	cellular response to biotic stimulus	1.753239e-2
GO:0000271	polysaccharide biosynthetic process	1.764032e-2
GO:0033092	positive regulation of immature T cell proliferation in thymus	1.783032e-2
GO:0006695	cholesterol biosynthetic process	1.783303e-2
GO:0007442	hindgut morphogenesis	1.792006e-2
GO:0032754	positive regulation of interleukin-5 production	1.800849e-2
GO:0010694	positive regulation of alkaline phosphatase activity	1.804911e-2
GO:0016071	mRNA metabolic process	1.822337e-2
GO:0045839	negative regulation of mitosis	1.830132e-2
GO:0002821	positive regulation of adaptive immune response	1.833855e-2
GO:0006555	methionine metabolic process	1.837555e-2
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	1.867066e-2
GO:0002377	immunoglobulin production	1.876130e-2
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	1.886598e-2
GO:0071577	zinc ion transmembrane transport	1.886598e-2
GO:0071313	cellular response to caffeine	1.894860e-2
GO:0048227	plasma membrane to endosome transport	1.894860e-2
GO:0001879	detection of yeast	1.894860e-2
GO:0042667	auditory receptor cell fate specification	1.894860e-2
GO:0045609	positive regulation of auditory receptor cell differentiation	1.894860e-2
GO:0045580	regulation of T cell differentiation	1.897934e-2
GO:0009309	amine biosynthetic process	1.900268e-2
GO:0032731	positive regulation of interleukin-1 beta production	1.911526e-2