Novel motif:132

name:	motif132_TCRCCAGWY

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0007208	activation of phospholipase C activity by serotonin receptor signaling pathway	9.498921e-9
GO:0031584	activation of phospholipase D activity	4.047972e-8
GO:0006335	DNA replication-dependent nucleosome assembly	5.097845e-8
GO:0002726	positive regulation of T cell cytokine production	2.631479e-7
GO:0043933	macromolecular complex subunit organization	2.665525e-7
GO:0033504	floor plate development	4.078147e-7
GO:0033693	neurofilament bundle assembly	4.249028e-7
GO:0050850	positive regulation of calcium-mediated signaling	4.823861e-7
GO:0045175	basal protein localization	4.951880e-7
GO:0048102	autophagic cell death	5.306918e-7
GO:0006054	N-acetylneuraminate metabolic process	1.148109e-6
GO:0032743	positive regulation of interleukin-2 production	1.765577e-6
GO:0031117	positive regulation of microtubule depolymerization	1.942611e-6
GO:0060052	neurofilament cytoskeleton organization	2.417083e-6
GO:0042274	ribosomal small subunit biogenesis	2.734436e-6
GO:0035845	photoreceptor cell outer segment organization	3.367223e-6
GO:0008089	anterograde axon cargo transport	3.597057e-6
GO:0015820	leucine transport	4.939805e-6
GO:0046549	retinal cone cell development	5.575790e-6
GO:2000409	positive regulation of T cell extravasation	6.635505e-6
GO:0043310	negative regulation of eosinophil degranulation	6.635505e-6
GO:0035696	monocyte extravasation	6.635505e-6
GO:0035705	T-helper 17 cell chemotaxis	6.635505e-6
GO:0006513	protein monoubiquitination	6.810147e-6
GO:0031333	negative regulation of protein complex assembly	7.932245e-6
GO:0072166	posterior mesonephric tubule development	8.556187e-6
GO:0032480	negative regulation of type I interferon production	8.569964e-6
GO:0044085	cellular component biogenesis	1.467104e-5
GO:0007522	visceral muscle development	1.487966e-5
GO:0043950	positive regulation of cAMP-mediated signaling	1.727867e-5
GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway	1.794523e-5
GO:0060248	detection of cell density by contact stimulus involved in contact inhibition	1.794523e-5
GO:0072285	mesenchymal to epithelial transition involved in metanephric renal vesicle formation	1.794523e-5
GO:0010509	polyamine homeostasis	1.794523e-5
GO:0007371	ventral midline determination	1.794523e-5
GO:0043654	recognition of apoptotic cell	1.863780e-5
GO:0035803	egg coat formation	1.940116e-5
GO:0019509	L-methionine salvage from methylthioadenosine	2.049294e-5
GO:0032472	Golgi calcium ion transport	2.212740e-5
GO:0032468	Golgi calcium ion homeostasis	2.212740e-5
GO:0030026	cellular manganese ion homeostasis	2.212740e-5
GO:0003017	lymph circulation	2.491967e-5
GO:0010611	regulation of cardiac muscle hypertrophy	2.588449e-5
GO:0010524	positive regulation of calcium ion transport into cytosol	2.806151e-5
GO:0032653	regulation of interleukin-10 production	2.946373e-5
GO:0001508	regulation of action potential	3.010398e-5
GO:0043488	regulation of mRNA stability	3.472315e-5
GO:0060409	positive regulation of acetylcholine metabolic process	3.489593e-5
GO:0034723	DNA replication-dependent nucleosome organization	3.958064e-5
GO:0060219	camera-type eye photoreceptor cell differentiation	3.960101e-5
GO:0048593	camera-type eye morphogenesis	4.012816e-5
GO:0042662	negative regulation of mesodermal cell fate specification	4.195510e-5
GO:0033505	floor plate morphogenesis	4.195510e-5
GO:0002709	regulation of T cell mediated immunity	4.499236e-5
GO:0021528	commissural neuron differentiation in spinal cord	4.949842e-5
GO:0042908	xenobiotic transport	4.958913e-5
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	5.525744e-5
GO:0061032	visceral serous pericardium development	5.525744e-5
GO:0007228	positive regulation of hh target transcription factor activity	5.581394e-5
GO:0022607	cellular component assembly	5.936315e-5
GO:0090136	epithelial cell-cell adhesion	6.183358e-5
GO:0070534	protein K63-linked ubiquitination	6.271385e-5
GO:0071822	protein complex subunit organization	6.971118e-5
GO:0044237	cellular metabolic process	7.233963e-5
GO:0000022	mitotic spindle elongation	7.263404e-5
GO:0033962	cytoplasmic mRNA processing body assembly	7.441452e-5
GO:0014743	regulation of muscle hypertrophy	7.493357e-5
GO:0071954	chemokine (C-C motif) ligand 11 production	7.873182e-5
GO:0043990	histone H2A-S1 phosphorylation	7.873182e-5
GO:2000525	positive regulation of T cell costimulation	7.873182e-5
GO:0002215	defense response to nematode	7.873182e-5
GO:0035708	interleukin-4-dependent isotype switching to IgE isotypes	7.873182e-5
GO:0035709	memory T cell activation	7.873182e-5
GO:0035712	T-helper 2 cell activation	7.873182e-5
GO:0002724	regulation of T cell cytokine production	8.223917e-5
GO:0019228	regulation of action potential in neuron	8.465932e-5
GO:0046709	IDP catabolic process	8.527895e-5
GO:0046032	ADP catabolic process	8.527895e-5
GO:0002711	positive regulation of T cell mediated immunity	9.294800e-5
GO:0032663	regulation of interleukin-2 production	9.572757e-5
GO:0031081	nuclear pore distribution	9.758692e-5
GO:0032456	endocytic recycling	9.866415e-5
GO:2000194	regulation of female gonad development	9.958311e-5
GO:0001570	vasculogenesis	1.002153e-4
GO:0030704	vitelline membrane formation	1.071974e-4
GO:0007418	ventral midline development	1.161955e-4
GO:0070936	protein K48-linked ubiquitination	1.176562e-4
GO:0034103	regulation of tissue remodeling	1.249241e-4
GO:0019896	axon transport of mitochondrion	1.283539e-4
GO:0050663	cytokine secretion	1.285826e-4
GO:2000109	regulation of macrophage apoptosis	1.305280e-4
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	1.305280e-4
GO:0060088	auditory receptor cell stereocilium organization	1.356465e-4
GO:0045110	intermediate filament bundle assembly	1.362357e-4
GO:0035051	cardiac cell differentiation	1.444833e-4
GO:0045109	intermediate filament organization	1.455891e-4
GO:0021508	floor plate formation	1.472245e-4
GO:0015755	fructose transport	1.472245e-4
GO:0070079	histone H4-R3 demethylation	1.499043e-4
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	1.499043e-4
GO:0070078	histone H3-R2 demethylation	1.499043e-4
GO:0003096	renal sodium ion transport	1.515465e-4
GO:0000731	DNA synthesis involved in DNA repair	1.515465e-4
GO:0032530	regulation of microvillus organization	1.583898e-4
GO:0046314	phosphocreatine biosynthetic process	1.595607e-4
GO:0006108	malate metabolic process	1.783880e-4
GO:0060356	leucine import	1.794685e-4
GO:0015827	tryptophan transport	1.896518e-4
GO:0002093	auditory receptor cell morphogenesis	1.916977e-4
GO:0032479	regulation of type I interferon production	1.928316e-4
GO:0070294	renal sodium ion absorption	1.961341e-4
GO:0048738	cardiac muscle tissue development	1.986198e-4
GO:0032984	macromolecular complex disassembly	2.025166e-4
GO:0060807	regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification	2.113963e-4
GO:0003142	cardiogenic plate morphogenesis	2.113963e-4
GO:0070837	dehydroascorbic acid transport	2.188553e-4
GO:0043254	regulation of protein complex assembly	2.237592e-4
GO:0032733	positive regulation of interleukin-10 production	2.319513e-4
GO:2000195	negative regulation of female gonad development	2.339884e-4
GO:0034767	positive regulation of ion transmembrane transport	2.371036e-4
GO:0006828	manganese ion transport	2.439573e-4
GO:2000299	negative regulation of Rho-dependent protein serine/threonine kinase activity	2.546618e-4
GO:0045736	negative regulation of cyclin-dependent protein kinase activity	2.554678e-4
GO:0051168	nuclear export	2.592665e-4
GO:0016525	negative regulation of angiogenesis	2.659644e-4
GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation	2.659863e-4
GO:0046635	positive regulation of alpha-beta T cell activation	2.718755e-4
GO:0000422	mitochondrion degradation	2.736167e-4
GO:0034351	negative regulation of glial cell apoptosis	2.828540e-4
GO:0070625	zymogen granule exocytosis	2.828540e-4
GO:0007506	gonadal mesoderm development	2.880857e-4
GO:0010226	response to lithium ion	3.076947e-4
GO:0051919	positive regulation of fibrinolysis	3.089831e-4
GO:0042780	tRNA 3'-end processing	3.096587e-4
GO:0010002	cardioblast differentiation	3.257915e-4
GO:0016485	protein processing	3.299778e-4
GO:0043241	protein complex disassembly	3.321097e-4
GO:0006325	chromatin organization	3.382287e-4
GO:0021523	somatic motor neuron differentiation	3.589849e-4
GO:0034623	cellular macromolecular complex disassembly	3.624548e-4
GO:0008152	metabolic process	3.667071e-4
GO:0010626	negative regulation of Schwann cell proliferation	3.861058e-4
GO:0032272	negative regulation of protein polymerization	4.062575e-4
GO:0072207	metanephric epithelium development	4.077235e-4
GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	4.096154e-4
GO:0006415	translational termination	4.216864e-4
GO:2000660	negative regulation of interleukin-1-mediated signaling pathway	4.223238e-4
GO:0000209	protein polyubiquitination	4.450200e-4
GO:0000244	assembly of spliceosomal tri-snRNP	4.517262e-4
GO:0007521	muscle cell fate determination	4.644771e-4
GO:0090073	positive regulation of protein homodimerization activity	4.690166e-4
GO:0060058	positive regulation of apoptosis involved in mammary gland involution	4.811154e-4
GO:0015742	alpha-ketoglutarate transport	4.859585e-4
GO:2000659	regulation of interleukin-1-mediated signaling pathway	4.865225e-4
GO:0016055	Wnt receptor signaling pathway	4.976553e-4
GO:0009812	flavonoid metabolic process	5.065909e-4
GO:0014038	regulation of Schwann cell differentiation	5.065909e-4
GO:0007207	activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway	5.065909e-4
GO:0046605	regulation of centrosome cycle	5.070497e-4
GO:0003334	keratinocyte development	5.198463e-4
GO:0034637	cellular carbohydrate biosynthetic process	5.283802e-4
GO:0044257	cellular protein catabolic process	5.325402e-4
GO:0034115	negative regulation of heterotypic cell-cell adhesion	5.335834e-4
GO:2000111	positive regulation of macrophage apoptosis	5.335834e-4
GO:0010522	regulation of calcium ion transport into cytosol	5.460104e-4
GO:0032621	interleukin-18 production	5.481174e-4
GO:0010824	regulation of centrosome duplication	5.521695e-4
GO:0043622	cortical microtubule organization	5.628806e-4
GO:0030103	vasopressin secretion	5.628806e-4
GO:0030163	protein catabolic process	5.636876e-4
GO:0003407	neural retina development	5.795191e-4
GO:0050848	regulation of calcium-mediated signaling	5.918379e-4
GO:0043624	cellular protein complex disassembly	6.130030e-4
GO:2001054	negative regulation of mesenchymal cell apoptosis	6.178468e-4
GO:0033036	macromolecule localization	6.215311e-4
GO:0071560	cellular response to transforming growth factor beta stimulus	6.342737e-4
GO:0009082	branched chain family amino acid biosynthetic process	6.342894e-4
GO:0065003	macromolecular complex assembly	6.496794e-4
GO:0008617	guanosine metabolic process	6.611388e-4
GO:0016043	cellular component organization	6.611829e-4
GO:0043487	regulation of RNA stability	6.638739e-4
GO:0001914	regulation of T cell mediated cytotoxicity	6.878904e-4
GO:0010624	regulation of Schwann cell proliferation	6.917620e-4
GO:0001701	in utero embryonic development	6.958352e-4
GO:0051024	positive regulation of immunoglobulin secretion	7.218994e-4
GO:0050685	positive regulation of mRNA processing	7.287850e-4
GO:0010613	positive regulation of cardiac muscle hypertrophy	7.289260e-4
GO:0000075	cell cycle checkpoint	7.326424e-4
GO:0031591	wybutosine biosynthetic process	7.488769e-4
GO:0072428	signal transduction involved in intra-S DNA damage checkpoint	7.488769e-4
GO:0045104	intermediate filament cytoskeleton organization	7.772790e-4
GO:0045124	regulation of bone resorption	7.910484e-4
GO:0000041	transition metal ion transport	8.022649e-4
GO:0008652	cellular amino acid biosynthetic process	8.097340e-4
GO:0051241	negative regulation of multicellular organismal process	8.174998e-4
GO:0001818	negative regulation of cytokine production	8.439615e-4
GO:0048242	epinephrine secretion	8.485722e-4
GO:0045218	zonula adherens maintenance	8.599506e-4
GO:0009698	phenylpropanoid metabolic process	8.599506e-4
GO:0055108	Golgi to transport vesicle transport	8.710224e-4
GO:0048871	multicellular organismal homeostasis	8.906360e-4
GO:0016568	chromatin modification	9.448658e-4
GO:0006629	lipid metabolic process	9.507618e-4
GO:0060911	cardiac cell fate commitment	9.567191e-4
GO:0046634	regulation of alpha-beta T cell activation	9.824185e-4
GO:0006414	translational elongation	1.002078e-3
GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation	1.007192e-3
GO:0043094	cellular metabolic compound salvage	1.010296e-3
GO:0070886	positive regulation of calcineurin-NFAT signaling pathway	1.019862e-3
GO:0003140	determination of left/right asymmetry in lateral mesoderm	1.019862e-3
GO:0030833	regulation of actin filament polymerization	1.051692e-3
GO:0003151	outflow tract morphogenesis	1.096354e-3
GO:0021940	positive regulation of cerebellar granule cell precursor proliferation	1.105997e-3
GO:0016577	histone demethylation	1.116415e-3
GO:0006482	protein demethylation	1.122545e-3
GO:0044091	membrane biogenesis	1.132452e-3
GO:0060956	endocardial cell differentiation	1.153293e-3
GO:0043503	skeletal muscle fiber adaptation	1.172277e-3
GO:0030509	BMP signaling pathway	1.193388e-3
GO:0055009	atrial cardiac muscle tissue morphogenesis	1.207795e-3
GO:0046850	regulation of bone remodeling	1.209185e-3
GO:0001709	cell fate determination	1.223428e-3
GO:0051967	negative regulation of synaptic transmission, glutamatergic	1.251883e-3
GO:0044238	primary metabolic process	1.276491e-3
GO:0007512	adult heart development	1.287783e-3
GO:0050954	sensory perception of mechanical stimulus	1.288185e-3
GO:0042989	sequestering of actin monomers	1.367296e-3
GO:0016567	protein ubiquitination	1.367522e-3
GO:0051095	regulation of helicase activity	1.382511e-3
GO:0097006	regulation of plasma lipoprotein particle levels	1.386711e-3
GO:0006939	smooth muscle contraction	1.390505e-3
GO:0060537	muscle tissue development	1.403128e-3
GO:0071840	cellular component organization or biogenesis	1.410837e-3
GO:0000237	leptotene	1.420448e-3
GO:0001916	positive regulation of T cell mediated cytotoxicity	1.423479e-3
GO:0042552	myelination	1.464807e-3
GO:0007344	pronuclear fusion	1.487794e-3
GO:0032793	positive regulation of CREB transcription factor activity	1.492680e-3
GO:0045103	intermediate filament-based process	1.514046e-3
GO:0018916	nitrobenzene metabolic process	1.528583e-3
GO:0006650	glycerophospholipid metabolic process	1.538484e-3
GO:0051604	protein maturation	1.543993e-3
GO:0032271	regulation of protein polymerization	1.544507e-3
GO:0031943	regulation of glucocorticoid metabolic process	1.559917e-3
GO:0070647	protein modification by small protein conjugation or removal	1.589301e-3
GO:0044260	cellular macromolecule metabolic process	1.597338e-3
GO:0019083	viral transcription	1.599690e-3
GO:0030431	sleep	1.617330e-3
GO:0010820	positive regulation of T cell chemotaxis	1.652147e-3
GO:0009083	branched chain family amino acid catabolic process	1.700452e-3
GO:0060304	regulation of phosphatidylinositol dephosphorylation	1.711939e-3
GO:0032474	otolith morphogenesis	1.711939e-3
GO:0032532	regulation of microvillus length	1.711939e-3
GO:0071338	positive regulation of hair follicle cell proliferation	1.728591e-3
GO:0032446	protein modification by small protein conjugation	1.740752e-3
GO:0034728	nucleosome organization	1.742322e-3
GO:0006094	gluconeogenesis	1.770537e-3
GO:0034393	positive regulation of smooth muscle cell apoptosis	1.776849e-3
GO:0071827	plasma lipoprotein particle organization	1.806965e-3
GO:0042693	muscle cell fate commitment	1.827546e-3
GO:0007600	sensory perception	1.833548e-3
GO:0006996	organelle organization	1.844334e-3
GO:0031638	zymogen activation	1.873953e-3
GO:0051135	positive regulation of NK T cell activation	1.890159e-3
GO:0051276	chromosome organization	1.893119e-3
GO:0007603	phototransduction, visible light	1.904050e-3
GO:0000271	polysaccharide biosynthetic process	1.932730e-3
GO:0048241	epinephrine transport	1.953214e-3
GO:0034391	regulation of smooth muscle cell apoptosis	1.955609e-3
GO:0010390	histone monoubiquitination	1.967934e-3
GO:0046380	N-acetylneuraminate biosynthetic process	1.984385e-3
GO:0006826	iron ion transport	1.994559e-3
GO:0060253	negative regulation of glial cell proliferation	1.995143e-3
GO:0015833	peptide transport	2.036936e-3
GO:0060070	canonical Wnt receptor signaling pathway	2.066144e-3
GO:0007218	neuropeptide signaling pathway	2.076917e-3
GO:0071285	cellular response to lithium ion	2.107453e-3
GO:0014829	vascular smooth muscle contraction	2.107453e-3
GO:0046849	bone remodeling	2.111783e-3
GO:0006511	ubiquitin-dependent protein catabolic process	2.115199e-3
GO:0070207	protein homotrimerization	2.130229e-3
GO:0048873	homeostasis of number of cells within a tissue	2.144504e-3
GO:0034139	regulation of toll-like receptor 3 signaling pathway	2.157277e-3
GO:0044265	cellular macromolecule catabolic process	2.160253e-3
GO:0006333	chromatin assembly or disassembly	2.206581e-3
GO:0006689	ganglioside catabolic process	2.213940e-3
GO:0007015	actin filament organization	2.226176e-3
GO:0031497	chromatin assembly	2.314899e-3
GO:0060997	dendritic spine morphogenesis	2.322291e-3
GO:0000082	G1/S transition of mitotic cell cycle	2.331336e-3
GO:0008625	induction of apoptosis via death domain receptors	2.337175e-3
GO:0042482	positive regulation of odontogenesis	2.340633e-3
GO:0015891	siderophore transport	2.388523e-3
GO:0032367	intracellular cholesterol transport	2.403200e-3
GO:0010259	multicellular organismal aging	2.450287e-3
GO:0050671	positive regulation of lymphocyte proliferation	2.464260e-3
GO:0006259	DNA metabolic process	2.483784e-3
GO:0030279	negative regulation of ossification	2.509636e-3
GO:0070293	renal absorption	2.518760e-3
GO:0048538	thymus development	2.526012e-3
GO:0001569	patterning of blood vessels	2.537679e-3
GO:0007213	muscarinic acetylcholine receptor signaling pathway	2.549499e-3
GO:0032612	interleukin-1 production	2.565340e-3
GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification	2.570641e-3
GO:0009057	macromolecule catabolic process	2.573808e-3
GO:0051129	negative regulation of cellular component organization	2.589222e-3
GO:0002639	positive regulation of immunoglobulin production	2.594145e-3
GO:0042396	phosphagen biosynthetic process	2.625788e-3
GO:0032602	chemokine production	2.625788e-3
GO:0008366	axon ensheathment	2.647347e-3
GO:0043462	regulation of ATPase activity	2.664807e-3
GO:0048486	parasympathetic nervous system development	2.685429e-3
GO:0009386	translational attenuation	2.712038e-3
GO:0070665	positive regulation of leukocyte proliferation	2.725784e-3
GO:0071559	response to transforming growth factor beta stimulus	2.768103e-3
GO:0046618	drug export	2.774312e-3
GO:0050701	interleukin-1 secretion	2.777503e-3
GO:0034621	cellular macromolecular complex subunit organization	2.801797e-3
GO:0007006	mitochondrial membrane organization	2.802856e-3
GO:0051603	proteolysis involved in cellular protein catabolic process	2.811928e-3
GO:0032946	positive regulation of mononuclear cell proliferation	2.818101e-3
GO:0034616	response to laminar fluid shear stress	2.926283e-3
GO:0030837	negative regulation of actin filament polymerization	2.937240e-3
GO:0072678	T cell migration	2.974076e-3
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	3.004396e-3
GO:0050432	catecholamine secretion	3.081054e-3
GO:0016578	histone deubiquitination	3.099470e-3
GO:0046474	glycerophospholipid biosynthetic process	3.132246e-3
GO:0030166	proteoglycan biosynthetic process	3.157373e-3
GO:0072284	metanephric S-shaped body morphogenesis	3.167179e-3
GO:0034136	negative regulation of toll-like receptor 2 signaling pathway	3.247923e-3
GO:0043090	amino acid import	3.256343e-3
GO:0007605	sensory perception of sound	3.266434e-3
GO:0019941	modification-dependent protein catabolic process	3.300534e-3
GO:0060383	positive regulation of DNA strand elongation	3.342023e-3
GO:0006461	protein complex assembly	3.471044e-3
GO:0019319	hexose biosynthetic process	3.489991e-3
GO:0051013	microtubule severing	3.490885e-3
GO:0042073	intraflagellar transport	3.490885e-3
GO:0019058	viral infectious cycle	3.535216e-3
GO:0035721	intraflagellar retrograde transport	3.548647e-3
GO:0009624	response to nematode	3.548647e-3
GO:0045652	regulation of megakaryocyte differentiation	3.624565e-3
GO:0046321	positive regulation of fatty acid oxidation	3.689947e-3
GO:0048193	Golgi vesicle transport	3.703883e-3
GO:0014706	striated muscle tissue development	3.811950e-3
GO:0021936	regulation of cerebellar granule cell precursor proliferation	3.879745e-3
GO:0043949	regulation of cAMP-mediated signaling	3.913357e-3
GO:0002679	respiratory burst involved in defense response	3.939661e-3
GO:0015893	drug transport	4.003080e-3
GO:0007250	activation of NF-kappaB-inducing kinase activity	4.003080e-3
GO:0007162	negative regulation of cell adhesion	4.005925e-3
GO:0008654	phospholipid biosynthetic process	4.072308e-3
GO:0043000	Golgi to plasma membrane CFTR protein transport	4.092900e-3
GO:0045660	positive regulation of neutrophil differentiation	4.141393e-3
GO:0043502	regulation of muscle adaptation	4.154060e-3
GO:0031424	keratinization	4.154583e-3
GO:0070271	protein complex biogenesis	4.195578e-3
GO:0043010	camera-type eye development	4.212817e-3
GO:0033260	DNA replication involved in S phase	4.217354e-3
GO:0051023	regulation of immunoglobulin secretion	4.243564e-3
GO:0051096	positive regulation of helicase activity	4.253347e-3
GO:0010807	regulation of synaptic vesicle priming	4.253347e-3
GO:0061056	sclerotome development	4.260946e-3
GO:0071897	DNA biosynthetic process	4.268901e-3
GO:0071777	positive regulation of cell cycle cytokinesis	4.301003e-3
GO:0031442	positive regulation of mRNA 3'-end processing	4.301003e-3
GO:0044255	cellular lipid metabolic process	4.309028e-3
GO:0071156	regulation of cell cycle arrest	4.327434e-3
GO:0032736	positive regulation of interleukin-13 production	4.370271e-3
GO:0051017	actin filament bundle assembly	4.479745e-3
GO:0060061	Spemann organizer formation	4.496038e-3
GO:0070301	cellular response to hydrogen peroxide	4.530418e-3
GO:0051937	catecholamine transport	4.568698e-3
GO:0070159	mitochondrial threonyl-tRNA aminoacylation	4.617171e-3
GO:0021703	locus ceruleus development	4.617171e-3
GO:0042592	homeostatic process	4.623800e-3
GO:0006385	transcription elongation from RNA polymerase III promoter	4.629061e-3
GO:0006386	termination of RNA polymerase III transcription	4.629061e-3
GO:0048840	otolith development	4.634212e-3
GO:0021897	forebrain astrocyte development	4.647581e-3
GO:0042045	epithelial fluid transport	4.696417e-3
GO:0043632	modification-dependent macromolecule catabolic process	4.791882e-3
GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	4.819203e-3
GO:0001894	tissue homeostasis	4.990085e-3
GO:0042391	regulation of membrane potential	5.009371e-3
GO:0035088	establishment or maintenance of apical/basal cell polarity	5.094343e-3
GO:0007568	aging	5.122454e-3
GO:0006474	N-terminal protein amino acid acetylation	5.150253e-3
GO:0060025	regulation of synaptic activity	5.164623e-3
GO:0006086	acetyl-CoA biosynthetic process from pyruvate	5.165273e-3
GO:2000503	positive regulation of natural killer cell chemotaxis	5.202810e-3
GO:2000513	positive regulation of granzyme A production	5.202810e-3
GO:2000538	positive regulation of B cell chemotaxis	5.202810e-3
GO:2000518	negative regulation of T-helper 1 cell activation	5.202810e-3
GO:2000412	positive regulation of thymocyte migration	5.202810e-3
GO:0035740	CD8-positive, alpha-beta T cell proliferation	5.202810e-3
GO:0017196	N-terminal peptidyl-methionine acetylation	5.202810e-3
GO:0071663	positive regulation of granzyme B production	5.202810e-3
GO:0035739	CD4-positive, alpha-beta T cell proliferation	5.202810e-3
GO:0035744	T-helper 1 cell cytokine production	5.202810e-3
GO:0000738	DNA catabolic process, exonucleolytic	5.372887e-3
GO:0010755	regulation of plasminogen activation	5.466081e-3
GO:0009103	lipopolysaccharide biosynthetic process	5.503898e-3
GO:0050435	beta-amyloid metabolic process	5.518260e-3
GO:0060789	hair follicle placode formation	5.688322e-3
GO:0071380	cellular response to prostaglandin E stimulus	5.712659e-3
GO:0045590	negative regulation of regulatory T cell differentiation	5.712659e-3
GO:0051301	cell division	5.750054e-3
GO:0010225	response to UV-C	5.800909e-3
GO:0021666	rhombomere 5 formation	5.931394e-3
GO:0021660	rhombomere 3 formation	5.931394e-3
GO:0043277	apoptotic cell clearance	6.094484e-3
GO:0045600	positive regulation of fat cell differentiation	6.116589e-3
GO:2000401	regulation of lymphocyte migration	6.133859e-3
GO:0046034	ATP metabolic process	6.221557e-3
GO:0001953	negative regulation of cell-matrix adhesion	6.229254e-3
GO:0045216	cell-cell junction organization	6.282153e-3
GO:0010936	negative regulation of macrophage cytokine production	6.283595e-3
GO:0006869	lipid transport	6.291579e-3
GO:0034405	response to fluid shear stress	6.329740e-3
GO:0042692	muscle cell differentiation	6.336650e-3
GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway	6.349350e-3
GO:0071241	cellular response to inorganic substance	6.358680e-3
GO:0030277	maintenance of gastrointestinal epithelium	6.387575e-3
GO:0060453	regulation of gastric acid secretion	6.435224e-3
GO:0021910	smoothened signaling pathway involved in ventral spinal cord patterning	6.437788e-3
GO:0010466	negative regulation of peptidase activity	6.485108e-3
GO:0031440	regulation of mRNA 3'-end processing	6.521481e-3
GO:0010224	response to UV-B	6.546145e-3
GO:0032874	positive regulation of stress-activated MAPK cascade	6.577014e-3
GO:0009309	amine biosynthetic process	6.589476e-3
GO:0002369	T cell cytokine production	6.621723e-3
GO:0009586	rhodopsin mediated phototransduction	6.638573e-3
GO:0008624	induction of apoptosis by extracellular signals	6.656904e-3
GO:0060249	anatomical structure homeostasis	6.683837e-3
GO:0060117	auditory receptor cell development	6.796944e-3
GO:0001886	endothelial cell morphogenesis	6.802066e-3
GO:0042474	middle ear morphogenesis	6.875276e-3
GO:0034143	regulation of toll-like receptor 4 signaling pathway	6.882033e-3
GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing	6.941864e-3
GO:0002091	negative regulation of receptor internalization	6.958679e-3
GO:0090265	positive regulation of immune complex clearance by monocytes and macrophages	6.958679e-3
GO:0006281	DNA repair	6.971380e-3
GO:0010887	negative regulation of cholesterol storage	7.024605e-3
GO:0033523	histone H2B ubiquitination	7.077881e-3
GO:0071844	cellular component assembly at cellular level	7.124195e-3
GO:0052314	phytoalexin metabolic process	7.187605e-3
GO:0060021	palate development	7.257161e-3
GO:0051917	regulation of fibrinolysis	7.266275e-3
GO:0006334	nucleosome assembly	7.270073e-3
GO:0035092	sperm chromatin condensation	7.374266e-3
GO:0006467	protein thiol-disulfide exchange	7.374266e-3
GO:0006356	regulation of transcription from RNA polymerase I promoter	7.421156e-3
GO:0010757	negative regulation of plasminogen activation	7.479505e-3
GO:0045453	bone resorption	7.500213e-3
GO:0051693	actin filament capping	7.506646e-3
GO:0021521	ventral spinal cord interneuron specification	7.603515e-3
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	7.628865e-3
GO:0070979	protein K11-linked ubiquitination	7.670526e-3
GO:0007321	sperm displacement	7.685831e-3
GO:0050973	detection of mechanical stimulus involved in equilibrioception	7.685831e-3
GO:0006710	androgen catabolic process	7.685831e-3
GO:0061031	endodermal digestive tract morphogenesis	7.713930e-3
GO:0002062	chondrocyte differentiation	7.735482e-3
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	7.764444e-3
GO:0030835	negative regulation of actin filament depolymerization	7.766988e-3
GO:0010980	positive regulation of vitamin D 24-hydroxylase activity	7.882507e-3
GO:0007197	inhibition of adenylate cyclase activity by muscarinic acetylcholine receptor signaling pathway	7.882507e-3
GO:0021871	forebrain regionalization	7.893227e-3
GO:0043585	nose morphogenesis	7.945125e-3
GO:0006413	translational initiation	7.949982e-3
GO:0060039	pericardium development	7.955516e-3
GO:0033634	positive regulation of cell-cell adhesion mediated by integrin	7.974849e-3
GO:0006542	glutamine biosynthetic process	7.974849e-3
GO:0006812	cation transport	8.107506e-3
GO:0060923	cardiac muscle cell fate commitment	8.122242e-3
GO:0032534	regulation of microvillus assembly	8.148709e-3
GO:0009181	purine ribonucleoside diphosphate catabolic process	8.148709e-3
GO:0021783	preganglionic parasympathetic nervous system development	8.193573e-3
GO:0007052	mitotic spindle organization	8.212109e-3
GO:0007210	serotonin receptor signaling pathway	8.221459e-3
GO:0046394	carboxylic acid biosynthetic process	8.222451e-3
GO:0071248	cellular response to metal ion	8.242420e-3
GO:0006665	sphingolipid metabolic process	8.267579e-3
GO:0006611	protein export from nucleus	8.296507e-3
GO:0032980	keratinocyte activation	8.305010e-3
GO:0043117	positive regulation of vascular permeability	8.309326e-3
GO:0001933	negative regulation of protein phosphorylation	8.328706e-3
GO:0035494	SNARE complex disassembly	8.360219e-3
GO:0006782	protoporphyrinogen IX biosynthetic process	8.360219e-3
GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development	8.434491e-3
GO:0016101	diterpenoid metabolic process	8.446730e-3
GO:2001076	positive regulation of metanephric ureteric bud development	8.483885e-3
GO:0007356	thorax and anterior abdomen determination	8.483885e-3
GO:0071843	cellular component biogenesis at cellular level	8.522126e-3
GO:0032729	positive regulation of interferon-gamma production	8.569599e-3
GO:0046638	positive regulation of alpha-beta T cell differentiation	8.624350e-3
GO:0006891	intra-Golgi vesicle-mediated transport	8.717040e-3
GO:0071236	cellular response to antibiotic	8.760301e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0032365	intracellular lipid transport	3.246538e-10
GO:0008360	regulation of cell shape	4.741561e-9
GO:0045332	phospholipid translocation	2.074391e-8
GO:0006910	phagocytosis, recognition	3.100033e-8
GO:0031055	chromatin remodeling at centromere	4.348077e-8
GO:0032367	intracellular cholesterol transport	9.223695e-8
GO:0034508	centromere complex assembly	1.357716e-7
GO:0019047	provirus integration	2.469419e-7
GO:0006911	phagocytosis, engulfment	1.508587e-6
GO:0008049	male courtship behavior	1.778900e-6
GO:0097035	regulation of membrane lipid distribution	3.199684e-6
GO:0038027	apolipoprotein A-I-mediated signaling pathway	3.732854e-6
GO:0042274	ribosomal small subunit biogenesis	3.758422e-6
GO:0006513	protein monoubiquitination	4.384923e-6
GO:0031508	centromeric heterochromatin formation	6.662994e-6
GO:0006581	acetylcholine catabolic process	9.702801e-6
GO:0007250	activation of NF-kappaB-inducing kinase activity	1.973865e-5
GO:0002536	respiratory burst involved in inflammatory response	2.266090e-5
GO:0006704	glucocorticoid biosynthetic process	2.581914e-5
GO:0007252	I-kappaB phosphorylation	2.739630e-5
GO:0007040	lysosome organization	3.293751e-5
GO:0007525	somatic muscle development	3.770816e-5
GO:0030194	positive regulation of blood coagulation	3.857946e-5
GO:0060174	limb bud formation	3.986051e-5
GO:0010724	regulation of definitive erythrocyte differentiation	4.055651e-5
GO:2001022	positive regulation of response to DNA damage stimulus	5.517854e-5
GO:0034441	plasma lipoprotein particle oxidation	6.391930e-5
GO:0008291	acetylcholine metabolic process	6.898730e-5
GO:2000378	negative regulation of reactive oxygen species metabolic process	7.490943e-5
GO:0000075	cell cycle checkpoint	7.914320e-5
GO:0060575	intestinal epithelial cell differentiation	8.290822e-5
GO:0002426	immunoglobulin production in mucosal tissue	8.437167e-5
GO:0006868	glutamine transport	9.014733e-5
GO:0031572	G2/M transition DNA damage checkpoint	9.043849e-5
GO:0060335	positive regulation of interferon-gamma-mediated signaling pathway	1.008636e-4
GO:0048343	paraxial mesodermal cell fate commitment	1.015418e-4
GO:0001300	chronological cell aging	1.015418e-4
GO:2000377	regulation of reactive oxygen species metabolic process	1.046528e-4
GO:0090026	positive regulation of monocyte chemotaxis	1.110197e-4
GO:0045299	otolith mineralization	1.160134e-4
GO:0045739	positive regulation of DNA repair	1.373203e-4
GO:0006364	rRNA processing	1.452350e-4
GO:0022613	ribonucleoprotein complex biogenesis	1.522475e-4
GO:0000492	box C/D snoRNP assembly	1.548040e-4
GO:0031576	G2/M transition checkpoint	1.584151e-4
GO:0021933	radial glia guided migration of cerebellar granule cell	1.676929e-4
GO:2000121	regulation of removal of superoxide radicals	1.748314e-4
GO:0014029	neural crest formation	1.839749e-4
GO:0090279	regulation of calcium ion import	1.951399e-4
GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.996079e-4
GO:0032007	negative regulation of TOR signaling cascade	2.032596e-4
GO:0002065	columnar/cuboidal epithelial cell differentiation	2.241599e-4
GO:0046827	positive regulation of protein export from nucleus	2.333651e-4
GO:0090280	positive regulation of calcium ion import	2.488609e-4
GO:0042428	serotonin metabolic process	2.531498e-4
GO:0048627	myoblast development	2.631947e-4
GO:0051597	response to methylmercury	2.763728e-4
GO:0006282	regulation of DNA repair	2.929771e-4
GO:0043507	positive regulation of JUN kinase activity	2.963917e-4
GO:0045919	positive regulation of cytolysis	3.028484e-4
GO:0003273	cell migration involved in endocardial cushion formation	3.028484e-4
GO:0033962	cytoplasmic mRNA processing body assembly	3.126658e-4
GO:0003341	cilium movement	3.250794e-4
GO:0000212	meiotic spindle organization	3.250794e-4
GO:2000781	positive regulation of double-strand break repair	3.284029e-4
GO:0006427	histidyl-tRNA aminoacylation	3.284029e-4
GO:0071840	cellular component organization or biogenesis	3.637342e-4
GO:0021681	cerebellar granular layer development	3.783898e-4
GO:0071824	protein-DNA complex subunit organization	4.030313e-4
GO:0042938	dipeptide transport	4.085318e-4
GO:0045875	negative regulation of sister chromatid cohesion	4.264979e-4
GO:0045212	neurotransmitter receptor biosynthetic process	4.267268e-4
GO:0031167	rRNA methylation	4.267268e-4
GO:0006044	N-acetylglucosamine metabolic process	4.377886e-4
GO:0030819	positive regulation of cAMP biosynthetic process	4.551714e-4
GO:0006909	phagocytosis	4.831203e-4
GO:0002724	regulation of T cell cytokine production	4.991467e-4
GO:0021683	cerebellar granular layer morphogenesis	5.570796e-4
GO:0007619	courtship behavior	5.696580e-4
GO:0045822	negative regulation of heart contraction	5.904218e-4
GO:0035329	hippo signaling cascade	5.970639e-4
GO:0035621	ER to Golgi ceramide transport	6.018990e-4
GO:0032743	positive regulation of interleukin-2 production	6.039978e-4
GO:0016072	rRNA metabolic process	6.095892e-4
GO:0002072	optic cup morphogenesis involved in camera-type eye development	6.174496e-4
GO:0007067	mitosis	6.313560e-4
GO:0071843	cellular component biogenesis at cellular level	6.405209e-4
GO:0002718	regulation of cytokine production involved in immune response	6.724283e-4
GO:0002541	activation of plasma proteins involved in acute inflammatory response	6.907397e-4
GO:0009789	positive regulation of abscisic acid mediated signaling pathway	7.621461e-4
GO:0002720	positive regulation of cytokine production involved in immune response	7.685647e-4
GO:0072355	histone H3-T3 phosphorylation	7.932145e-4
GO:0002462	tolerance induction to nonself antigen	7.932145e-4
GO:0042891	antibiotic transport	8.391588e-4
GO:0071156	regulation of cell cycle arrest	8.502058e-4
GO:2000036	regulation of stem cell maintenance	8.684368e-4
GO:0010829	negative regulation of glucose transport	9.623235e-4
GO:0051583	dopamine uptake	9.652319e-4
GO:0071841	cellular component organization or biogenesis at cellular level	1.010326e-3
GO:0007042	lysosomal lumen acidification	1.051385e-3
GO:0048285	organelle fission	1.081893e-3
GO:0051725	protein de-ADP-ribosylation	1.087785e-3
GO:0005997	xylulose metabolic process	1.107579e-3
GO:0060179	male mating behavior	1.107579e-3
GO:0050820	positive regulation of coagulation	1.118812e-3
GO:0043044	ATP-dependent chromatin remodeling	1.163089e-3
GO:0021695	cerebellar cortex development	1.179249e-3
GO:0060206	estrous cycle phase	1.259296e-3
GO:0046325	negative regulation of glucose import	1.271402e-3
GO:0016310	phosphorylation	1.277932e-3
GO:0000087	M phase of mitotic cell cycle	1.300332e-3
GO:0006468	protein phosphorylation	1.311989e-3
GO:0002726	positive regulation of T cell cytokine production	1.351541e-3
GO:0021587	cerebellum morphogenesis	1.395629e-3
GO:0006464	protein modification process	1.409920e-3
GO:0000154	rRNA modification	1.429234e-3
GO:0035357	peroxisome proliferator activated receptor signaling pathway	1.473770e-3
GO:0055091	phospholipid homeostasis	1.481962e-3
GO:0051403	stress-activated MAPK cascade	1.503592e-3
GO:0042761	very long-chain fatty acid biosynthetic process	1.560987e-3
GO:0002821	positive regulation of adaptive immune response	1.582523e-3
GO:0070509	calcium ion import	1.585447e-3
GO:0034625	fatty acid elongation, monounsaturated fatty acid	1.587857e-3
GO:0048822	enucleate erythrocyte development	1.617072e-3
GO:0035507	regulation of myosin-light-chain-phosphatase activity	1.634974e-3
GO:0010761	fibroblast migration	1.662886e-3
GO:0002115	store-operated calcium entry	1.671451e-3
GO:0001788	antibody-dependent cellular cytotoxicity	1.698647e-3
GO:0042254	ribosome biogenesis	1.786654e-3
GO:0034080	CenH3-containing nucleosome assembly at centromere	1.825969e-3
GO:0060739	mesenchymal-epithelial cell signaling involved in prostate gland development	1.825969e-3
GO:0034509	centromeric core chromatin assembly	1.825969e-3
GO:0002897	positive regulation of central B cell tolerance induction	1.825969e-3
GO:0002508	central tolerance induction	1.825969e-3
GO:0016043	cellular component organization	1.844355e-3
GO:0034621	cellular macromolecular complex subunit organization	1.885429e-3
GO:0009259	ribonucleotide metabolic process	1.892177e-3
GO:0065004	protein-DNA complex assembly	1.893690e-3
GO:0048298	positive regulation of isotype switching to IgA isotypes	1.943406e-3
GO:0046034	ATP metabolic process	1.944403e-3
GO:0043412	macromolecule modification	2.000474e-3
GO:0018209	peptidyl-serine modification	2.040530e-3
GO:0015817	histidine transport	2.090052e-3
GO:0010755	regulation of plasminogen activation	2.134150e-3
GO:0030041	actin filament polymerization	2.148944e-3
GO:0001805	positive regulation of type III hypersensitivity	2.185767e-3
GO:0006269	DNA replication, synthesis of RNA primer	2.185767e-3
GO:0071826	ribonucleoprotein complex subunit organization	2.186452e-3
GO:0055098	response to low-density lipoprotein particle stimulus	2.188549e-3
GO:0010875	positive regulation of cholesterol efflux	2.188549e-3
GO:0000725	recombinational repair	2.224922e-3
GO:0010611	regulation of cardiac muscle hypertrophy	2.273446e-3
GO:0001667	ameboidal cell migration	2.289256e-3
GO:0097006	regulation of plasma lipoprotein particle levels	2.294856e-3
GO:0009181	purine ribonucleoside diphosphate catabolic process	2.350840e-3
GO:0050684	regulation of mRNA processing	2.361273e-3
GO:0032376	positive regulation of cholesterol transport	2.363483e-3
GO:0060155	platelet dense granule organization	2.420033e-3
GO:0044267	cellular protein metabolic process	2.452857e-3
GO:0071636	positive regulation of transforming growth factor beta production	2.480066e-3
GO:0045646	regulation of erythrocyte differentiation	2.482189e-3
GO:0071034	CUT catabolic process	2.508197e-3
GO:0071287	cellular response to manganese ion	2.523927e-3
GO:0003016	respiratory system process	2.592774e-3
GO:0014034	neural crest cell fate commitment	2.642740e-3
GO:0009586	rhodopsin mediated phototransduction	2.642740e-3
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	2.648993e-3
GO:0015804	neutral amino acid transport	2.679362e-3
GO:0009150	purine ribonucleotide metabolic process	2.760255e-3
GO:0030520	estrogen receptor signaling pathway	2.818843e-3
GO:0034767	positive regulation of ion transmembrane transport	2.828113e-3
GO:0019068	virion assembly	2.833984e-3
GO:0090074	negative regulation of protein homodimerization activity	2.833984e-3
GO:0006407	rRNA export from nucleus	2.833984e-3
GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity	2.889046e-3
GO:0006930	substrate-dependent cell migration, cell extension	2.889046e-3
GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly	2.931296e-3
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	2.975345e-3
GO:0032862	activation of Rho GTPase activity	3.015195e-3
GO:0000077	DNA damage checkpoint	3.112297e-3
GO:0034470	ncRNA processing	3.136512e-3
GO:0006040	amino sugar metabolic process	3.153428e-3
GO:0010390	histone monoubiquitination	3.167710e-3
GO:0060563	neuroepithelial cell differentiation	3.169637e-3
GO:0043486	histone exchange	3.229280e-3
GO:0007094	mitotic cell cycle spindle assembly checkpoint	3.229280e-3
GO:0002889	regulation of immunoglobulin mediated immune response	3.232730e-3
GO:0034622	cellular macromolecular complex assembly	3.324624e-3
GO:0006865	amino acid transport	3.333986e-3
GO:0006586	indolalkylamine metabolic process	3.381885e-3
GO:0010614	negative regulation of cardiac muscle hypertrophy	3.382025e-3
GO:0006754	ATP biosynthetic process	3.401538e-3
GO:0060992	response to fungicide	3.427283e-3
GO:0034626	fatty acid elongation, polyunsaturated fatty acid	3.455172e-3
GO:0009205	purine ribonucleoside triphosphate metabolic process	3.548595e-3
GO:0009642	response to light intensity	3.584374e-3
GO:0032914	positive regulation of transforming growth factor beta1 production	3.592733e-3
GO:0090075	relaxation of muscle	3.617034e-3
GO:0010900	negative regulation of phosphatidylcholine catabolic process	3.658385e-3
GO:0007015	actin filament organization	3.666376e-3
GO:0009201	ribonucleoside triphosphate biosynthetic process	3.696237e-3
GO:0070534	protein K63-linked ubiquitination	3.712470e-3
GO:0009145	purine nucleoside triphosphate biosynthetic process	3.786097e-3
GO:0006867	asparagine transport	3.793830e-3
GO:0071872	cellular response to epinephrine stimulus	3.831397e-3
GO:0070318	positive regulation of G0 to G1 transition	3.831397e-3
GO:0071174	mitotic cell cycle spindle checkpoint	3.889602e-3
GO:0002636	positive regulation of germinal center formation	3.889602e-3
GO:0009199	ribonucleoside triphosphate metabolic process	3.897045e-3
GO:0010944	negative regulation of transcription by competitive promoter binding	3.906699e-3
GO:0060055	angiogenesis involved in wound healing	3.951840e-3
GO:0010874	regulation of cholesterol efflux	3.959264e-3
GO:0043277	apoptotic cell clearance	3.964903e-3
GO:0060412	ventricular septum morphogenesis	3.993954e-3
GO:0022604	regulation of cell morphogenesis	4.007402e-3
GO:0071108	protein K48-linked deubiquitination	4.073069e-3
GO:0050908	detection of light stimulus involved in visual perception	4.073069e-3
GO:0043380	regulation of memory T cell differentiation	4.099784e-3
GO:0030497	fatty acid elongation	4.110756e-3
GO:0031570	DNA integrity checkpoint	4.121051e-3
GO:0046466	membrane lipid catabolic process	4.318001e-3
GO:0014743	regulation of muscle hypertrophy	4.318001e-3
GO:0032074	negative regulation of nuclease activity	4.354584e-3
GO:0007019	microtubule depolymerization	4.354584e-3
GO:0021680	cerebellar Purkinje cell layer development	4.378988e-3
GO:0046825	regulation of protein export from nucleus	4.379641e-3
GO:0021575	hindbrain morphogenesis	4.440736e-3
GO:0015802	basic amino acid transport	4.464287e-3
GO:0009895	negative regulation of catabolic process	4.520994e-3
GO:0001985	negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure	4.524177e-3
GO:0060346	bone trabecula formation	4.734620e-3
GO:0048025	negative regulation of nuclear mRNA splicing, via spliceosome	4.755360e-3
GO:0035405	histone-threonine phosphorylation	4.755360e-3
GO:0021707	cerebellar granule cell differentiation	4.770178e-3
GO:0035083	cilium axoneme assembly	4.872460e-3
GO:0002430	complement receptor mediated signaling pathway	4.872460e-3
GO:0060285	ciliary cell motility	4.879927e-3
GO:0060044	negative regulation of cardiac muscle cell proliferation	5.005544e-3
GO:0071842	cellular component organization at cellular level	5.015316e-3
GO:0045988	negative regulation of striated muscle contraction	5.047137e-3
GO:0042177	negative regulation of protein catabolic process	5.093140e-3
GO:0009144	purine nucleoside triphosphate metabolic process	5.234942e-3
GO:0019368	fatty acid elongation, unsaturated fatty acid	5.309343e-3
GO:0045647	negative regulation of erythrocyte differentiation	5.326412e-3
GO:0007290	spermatid nucleus elongation	5.361551e-3
GO:0048671	negative regulation of collateral sprouting	5.361551e-3
GO:0009141	nucleoside triphosphate metabolic process	5.371384e-3
GO:0016482	cytoplasmic transport	5.392002e-3
GO:0002542	Factor XII activation	5.392002e-3
GO:0030801	positive regulation of cyclic nucleotide metabolic process	5.411697e-3
GO:0007339	binding of sperm to zona pellucida	5.578220e-3
GO:0006824	cobalt ion transport	5.583022e-3
GO:0090076	relaxation of skeletal muscle	5.593809e-3
GO:0032763	regulation of mast cell cytokine production	5.593809e-3
GO:0032470	elevation of endoplasmic reticulum calcium ion concentration	5.593809e-3
GO:0032611	interleukin-1 beta production	5.635409e-3
GO:0051301	cell division	5.643484e-3
GO:0034660	ncRNA metabolic process	5.709054e-3
GO:0001909	leukocyte mediated cytotoxicity	5.712804e-3
GO:0021696	cerebellar cortex morphogenesis	5.767219e-3
GO:0006897	endocytosis	5.812737e-3
GO:0006882	cellular zinc ion homeostasis	5.822631e-3
GO:0007289	spermatid nucleus differentiation	5.996593e-3
GO:0002645	positive regulation of tolerance induction	5.996593e-3
GO:0006222	UMP biosynthetic process	6.085699e-3
GO:0010310	regulation of hydrogen peroxide metabolic process	6.133377e-3
GO:0002700	regulation of production of molecular mediator of immune response	6.153621e-3
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	6.192485e-3
GO:0055094	response to lipoprotein stimulus	6.284674e-3
GO:0022618	ribonucleoprotein complex assembly	6.288850e-3
GO:0006782	protoporphyrinogen IX biosynthetic process	6.302788e-3
GO:0043933	macromolecular complex subunit organization	6.374725e-3
GO:0000959	mitochondrial RNA metabolic process	6.546692e-3
GO:0006857	oligopeptide transport	6.546891e-3
GO:0030804	positive regulation of cyclic nucleotide biosynthetic process	6.598921e-3
GO:0007341	penetration of zona pellucida	6.642486e-3
GO:0001913	T cell mediated cytotoxicity	6.743093e-3
GO:0016574	histone ubiquitination	6.896831e-3
GO:0009142	nucleoside triphosphate biosynthetic process	7.227087e-3
GO:0015837	amine transport	7.344225e-3
GO:0048294	negative regulation of isotype switching to IgE isotypes	7.459027e-3
GO:0002829	negative regulation of type 2 immune response	7.459027e-3
GO:0015914	phospholipid transport	7.550099e-3
GO:0007052	mitotic spindle organization	7.556386e-3
GO:0072385	minus-end-directed organelle transport along microtubule	7.575799e-3
GO:0071670	smooth muscle cell chemotaxis	7.575799e-3
GO:0060981	cell migration involved in coronary angiogenesis	7.575799e-3
GO:0000073	spindle pole body separation	7.575799e-3
GO:0045792	negative regulation of cell size	7.640963e-3
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	7.697680e-3
GO:0002706	regulation of lymphocyte mediated immunity	7.714150e-3
GO:0070537	histone H2A K63-linked deubiquitination	7.760331e-3
GO:2000736	regulation of stem cell differentiation	7.788052e-3
GO:0010694	positive regulation of alkaline phosphatase activity	7.919895e-3
GO:0000186	activation of MAPKK activity	8.022544e-3
GO:0032788	saturated monocarboxylic acid metabolic process	8.033927e-3
GO:0032789	unsaturated monocarboxylic acid metabolic process	8.033927e-3
GO:0034197	triglyceride transport	8.033927e-3
GO:0051447	negative regulation of meiotic cell cycle	8.033927e-3
GO:0032782	bile acid secretion	8.033927e-3
GO:0010756	positive regulation of plasminogen activation	8.033927e-3
GO:0003096	renal sodium ion transport	8.033927e-3
GO:0007597	blood coagulation, intrinsic pathway	8.033927e-3
GO:0003357	noradrenergic neuron differentiation	8.051242e-3
GO:0043506	regulation of JUN kinase activity	8.197366e-3
GO:0033205	cell cycle cytokinesis	8.226694e-3
GO:0034063	stress granule assembly	8.267060e-3
GO:0033523	histone H2B ubiquitination	8.267060e-3
GO:0010921	regulation of phosphatase activity	8.368498e-3
GO:0010459	negative regulation of heart rate	8.457523e-3
GO:0009584	detection of visible light	8.457523e-3
GO:0042732	D-xylose metabolic process	8.478196e-3
GO:0002711	positive regulation of T cell mediated immunity	8.485115e-3
GO:0021539	subthalamus development	8.814137e-3
GO:0035562	negative regulation of chromatin binding	8.814137e-3
GO:0006481	C-terminal protein methylation	8.814137e-3
GO:0002635	negative regulation of germinal center formation	8.814137e-3
GO:0002642	positive regulation of immunoglobulin biosynthetic process	8.814137e-3
GO:0035330	regulation of hippo signaling cascade	8.839668e-3
GO:0032025	response to cobalt ion	8.839668e-3
GO:0048199	vesicle targeting, to, from or within Golgi	8.883902e-3
GO:0032764	negative regulation of mast cell cytokine production	8.883902e-3
GO:0042747	circadian sleep/wake cycle, REM sleep	8.932705e-3
GO:0032229	negative regulation of synaptic transmission, GABAergic	8.971719e-3
GO:0031109	microtubule polymerization or depolymerization	8.971719e-3
GO:0021506	anterior neuropore closure	9.002413e-3
GO:0001569	patterning of blood vessels	9.126837e-3
GO:0034505	tooth mineralization	9.160869e-3
GO:0032446	protein modification by small protein conjugation	9.350079e-3
GO:0061303	cornea development in camera-type eye	9.443507e-3
GO:0002444	myeloid leukocyte mediated immunity	9.452837e-3
GO:0030149	sphingolipid catabolic process	9.717039e-3
GO:0019377	glycolipid catabolic process	9.803162e-3
GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	9.803162e-3
GO:0060041	retina development in camera-type eye	9.865500e-3
GO:0034394	protein localization at cell surface	9.884295e-3
GO:0055069	zinc ion homeostasis	9.941862e-3
GO:0032069	regulation of nuclease activity	1.020155e-2
GO:0033131	regulation of glucokinase activity	1.020155e-2
GO:0014741	negative regulation of muscle hypertrophy	1.020155e-2
GO:0060359	response to ammonium ion	1.027207e-2
GO:0048840	otolith development	1.027207e-2
GO:0031953	negative regulation of protein autophosphorylation	1.031348e-2
GO:0046209	nitric oxide metabolic process	1.051466e-2
GO:0019695	choline metabolic process	1.051983e-2
GO:0061383	trabecula morphogenesis	1.054208e-2
GO:0050930	induction of positive chemotaxis	1.054580e-2
GO:0000038	very long-chain fatty acid metabolic process	1.062928e-2
GO:0001556	oocyte maturation	1.064921e-2
GO:0070316	regulation of G0 to G1 transition	1.070692e-2
GO:0050917	sensory perception of umami taste	1.070692e-2
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	1.092291e-2
GO:0009260	ribonucleotide biosynthetic process	1.093259e-2
GO:0080135	regulation of cellular response to stress	1.105295e-2
GO:0032319	regulation of Rho GTPase activity	1.105621e-2
GO:0002819	regulation of adaptive immune response	1.107920e-2
GO:0002537	nitric oxide production involved in inflammatory response	1.116944e-2
GO:0006421	asparaginyl-tRNA aminoacylation	1.116944e-2
GO:0006689	ganglioside catabolic process	1.160090e-2
GO:0014009	glial cell proliferation	1.172206e-2
GO:0043353	enucleate erythrocyte differentiation	1.172234e-2
GO:0050912	detection of chemical stimulus involved in sensory perception of taste	1.172234e-2
GO:0031444	slow-twitch skeletal muscle fiber contraction	1.178027e-2
GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	1.178027e-2
GO:0002485	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	1.178027e-2
GO:0008211	glucocorticoid metabolic process	1.207525e-2
GO:0002532	production of molecular mediator involved in inflammatory response	1.223385e-2
GO:0061108	seminal vesicle epithelium development	1.233679e-2
GO:0051684	maintenance of Golgi location	1.233679e-2
GO:0061110	dense core granule biogenesis	1.233679e-2
GO:0060520	activation of prostate induction by androgen receptor signaling pathway	1.233679e-2
GO:0071035	nuclear polyadenylation-dependent rRNA catabolic process	1.233679e-2
GO:0090331	negative regulation of platelet aggregation	1.233679e-2
GO:0071048	nuclear retention of unspliced pre-mRNA at the site of transcription	1.233679e-2
GO:0050983	deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase	1.233679e-2
GO:0070899	mitochondrial tRNA wobble uridine modification	1.233679e-2
GO:0019102	male somatic sex determination	1.233679e-2
GO:0002365	gamma-delta T cell lineage commitment	1.233679e-2
GO:0001971	negative regulation of activation of membrane attack complex	1.233679e-2
GO:0045720	negative regulation of integrin biosynthetic process	1.233679e-2
GO:0030150	protein import into mitochondrial matrix	1.233679e-2
GO:0032620	interleukin-17 production	1.233679e-2
GO:0035545	determination of left/right asymmetry in nervous system	1.233679e-2
GO:0035499	carnosine biosynthetic process	1.233679e-2
GO:0007521	muscle cell fate determination	1.255803e-2
GO:0002328	pro-B cell differentiation	1.255803e-2
GO:0035036	sperm-egg recognition	1.277651e-2
GO:0002643	regulation of tolerance induction	1.278316e-2
GO:0006709	progesterone catabolic process	1.295137e-2
GO:0000724	double-strand break repair via homologous recombination	1.315678e-2
GO:0045726	positive regulation of integrin biosynthetic process	1.316741e-2
GO:0000059	protein import into nucleus, docking	1.316741e-2
GO:0060022	hard palate development	1.328713e-2
GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	1.334047e-2
GO:0016476	regulation of embryonic cell shape	1.334047e-2
GO:0046709	IDP catabolic process	1.334047e-2
GO:0046032	ADP catabolic process	1.334047e-2
GO:0060696	regulation of phospholipid catabolic process	1.341369e-2
GO:2001020	regulation of response to DNA damage stimulus	1.363090e-2
GO:0035303	regulation of dephosphorylation	1.378567e-2
GO:0060900	embryonic camera-type eye formation	1.382419e-2
GO:0042402	cellular biogenic amine catabolic process	1.382419e-2
GO:0043654	recognition of apoptotic cell	1.397227e-2
GO:0006796	phosphate-containing compound metabolic process	1.422193e-2
GO:0050702	interleukin-1 beta secretion	1.429199e-2
GO:0002634	regulation of germinal center formation	1.433917e-2
GO:0007095	mitotic cell cycle G2/M transition DNA damage checkpoint	1.441158e-2
GO:0070584	mitochondrion morphogenesis	1.441619e-2
GO:0045760	positive regulation of action potential	1.441619e-2
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	1.449368e-2
GO:0006108	malate metabolic process	1.449368e-2
GO:0046942	carboxylic acid transport	1.457449e-2
GO:0034198	cellular response to amino acid starvation	1.468223e-2
GO:0016576	histone dephosphorylation	1.468223e-2
GO:0061386	closure of optic fissure	1.468234e-2
GO:0035332	positive regulation of hippo signaling cascade	1.468234e-2
GO:2000147	positive regulation of cell motility	1.472105e-2
GO:0033505	floor plate morphogenesis	1.480010e-2
GO:0070842	aggresome assembly	1.480010e-2
GO:0015855	pyrimidine base transport	1.480010e-2
GO:0019538	protein metabolic process	1.482757e-2
GO:0002702	positive regulation of production of molecular mediator of immune response	1.483952e-2
GO:0048596	embryonic camera-type eye morphogenesis	1.499814e-2
GO:0071548	response to dexamethasone stimulus	1.504659e-2
GO:0051045	negative regulation of membrane protein ectodomain proteolysis	1.509415e-2
GO:0009220	pyrimidine ribonucleotide biosynthetic process	1.511043e-2
GO:0031448	positive regulation of fast-twitch skeletal muscle fiber contraction	1.528739e-2
GO:0030203	glycosaminoglycan metabolic process	1.547548e-2
GO:0001961	positive regulation of cytokine-mediated signaling pathway	1.547908e-2
GO:0090275	negative regulation of somatostatin secretion	1.576966e-2
GO:0070935	3'-UTR-mediated mRNA stabilization	1.583606e-2
GO:0070483	detection of hypoxia	1.583606e-2
GO:0006434	seryl-tRNA aminoacylation	1.583606e-2
GO:0010501	RNA secondary structure unwinding	1.583606e-2
GO:0043248	proteasome assembly	1.602610e-2
GO:0033239	negative regulation of cellular amine metabolic process	1.602610e-2
GO:0033119	negative regulation of RNA splicing	1.610798e-2
GO:0002438	acute inflammatory response to antigenic stimulus	1.610798e-2
GO:0051642	centrosome localization	1.611005e-2
GO:0035518	histone H2A monoubiquitination	1.640679e-2
GO:0021776	smoothened signaling pathway involved in spinal cord motor neuron cell fate specification	1.641704e-2
GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification	1.641704e-2
GO:0071705	nitrogen compound transport	1.654017e-2
GO:0006405	RNA export from nucleus	1.659897e-2
GO:0008361	regulation of cell size	1.679529e-2
GO:0042490	mechanoreceptor differentiation	1.689092e-2
GO:0034105	positive regulation of tissue remodeling	1.692085e-2
GO:0051248	negative regulation of protein metabolic process	1.703660e-2
GO:0055118	negative regulation of cardiac muscle contraction	1.713816e-2
GO:0007603	phototransduction, visible light	1.713816e-2
GO:0051272	positive regulation of cellular component movement	1.714198e-2
GO:0050680	negative regulation of epithelial cell proliferation	1.738922e-2
GO:0034614	cellular response to reactive oxygen species	1.773058e-2
GO:0018193	peptidyl-amino acid modification	1.794875e-2
GO:0031440	regulation of mRNA 3'-end processing	1.795507e-2
GO:0006935	chemotaxis	1.802643e-2
GO:0009117	nucleotide metabolic process	1.844575e-2
GO:0046483	heterocycle metabolic process	1.849672e-2
GO:0042491	auditory receptor cell differentiation	1.849946e-2
GO:0001974	blood vessel remodeling	1.851101e-2
GO:0009313	oligosaccharide catabolic process	1.858040e-2
GO:0002024	diet induced thermogenesis	1.858040e-2
GO:0033700	phospholipid efflux	1.869484e-2
GO:0016567	protein ubiquitination	1.878035e-2
GO:0008207	C21-steroid hormone metabolic process	1.895392e-2
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	1.916701e-2
GO:0000028	ribosomal small subunit assembly	1.916701e-2
GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation	1.916701e-2
GO:0006750	glutathione biosynthetic process	1.919565e-2
GO:0045780	positive regulation of bone resorption	1.929228e-2
GO:2000678	negative regulation of transcription regulatory region DNA binding	1.929287e-2
GO:0032863	activation of Rac GTPase activity	1.929287e-2
GO:0060018	astrocyte fate commitment	1.929287e-2
GO:0006996	organelle organization	1.932543e-2
GO:0003416	endochondral bone growth	1.946965e-2
GO:0045629	negative regulation of T-helper 2 cell differentiation	1.962909e-2
GO:0072528	pyrimidine-containing compound biosynthetic process	1.967972e-2
GO:0072527	pyrimidine-containing compound metabolic process	1.983303e-2
GO:0021678	third ventricle development	1.988735e-2
GO:0016073	snRNA metabolic process	1.996096e-2
GO:0071879	positive regulation of adrenergic receptor signaling pathway	1.999149e-2
GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development	1.999149e-2
GO:0006499	N-terminal protein myristoylation	1.999149e-2
GO:0015819	lysine transport	1.999149e-2
GO:0015822	ornithine transport	1.999149e-2
GO:0018105	peptidyl-serine phosphorylation	2.008191e-2
GO:0002703	regulation of leukocyte mediated immunity	2.025896e-2
GO:0042330	taxis	2.034591e-2
GO:0033133	positive regulation of glucokinase activity	2.036705e-2
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	2.036705e-2
GO:0000279	M phase	2.046285e-2
GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	2.046430e-2
GO:0021508	floor plate formation	2.048938e-2
GO:0009231	riboflavin biosynthetic process	2.048938e-2
GO:0051917	regulation of fibrinolysis	2.098314e-2
GO:0007271	synaptic transmission, cholinergic	2.106626e-2
GO:0006302	double-strand break repair	2.123807e-2
GO:0043966	histone H3 acetylation	2.137535e-2
GO:0018149	peptide cross-linking	2.138288e-2
GO:2000162	negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis	2.147720e-2