Novel motif:93

name:	motif93_TANTMTCTRWAT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0050896	response to stimulus	9.249960e-27
GO:0007154	cell communication	3.495442e-20
GO:0023052	signaling	9.794193e-19
GO:0032501	multicellular organismal process	3.727483e-18
GO:0051716	cellular response to stimulus	5.354592e-17
GO:0007165	signal transduction	6.658787e-16
GO:0048513	organ development	9.100908e-16
GO:0002376	immune system process	2.850087e-15
GO:0048856	anatomical structure development	4.263344e-15
GO:0019674	NAD metabolic process	1.888026e-14
GO:0009888	tissue development	8.188344e-14
GO:0048731	system development	1.070813e-13
GO:0006950	response to stress	3.574449e-13
GO:0007275	multicellular organismal development	8.702316e-13
GO:0007166	cell surface receptor linked signaling pathway	1.903971e-12
GO:0032502	developmental process	2.174969e-12
GO:0009611	response to wounding	8.010971e-12
GO:0042221	response to chemical stimulus	1.114243e-11
GO:0019359	nicotinamide nucleotide biosynthetic process	3.303790e-11
GO:0031444	slow-twitch skeletal muscle fiber contraction	8.216976e-11
GO:0019363	pyridine nucleotide biosynthetic process	9.631913e-11
GO:0009653	anatomical structure morphogenesis	1.027820e-10
GO:0050789	regulation of biological process	1.754479e-10
GO:0009435	NAD biosynthetic process	2.856017e-10
GO:0043589	skin morphogenesis	3.124839e-10
GO:0002551	mast cell chemotaxis	3.708063e-10
GO:0030199	collagen fibril organization	5.332267e-10
GO:0046496	nicotinamide nucleotide metabolic process	5.468115e-10
GO:0003008	system process	8.084169e-10
GO:0051707	response to other organism	8.710539e-10
GO:0048660	regulation of smooth muscle cell proliferation	8.979171e-10
GO:0001542	ovulation from ovarian follicle	1.017656e-9
GO:0001915	negative regulation of T cell mediated cytotoxicity	1.486056e-9
GO:0015669	gas transport	1.645627e-9
GO:0051179	localization	1.930724e-9
GO:0065007	biological regulation	3.337122e-9
GO:0021858	GABAergic neuron differentiation in basal ganglia	4.219168e-9
GO:0050794	regulation of cellular process	4.985937e-9
GO:0031099	regeneration	6.147525e-9
GO:0019362	pyridine nucleotide metabolic process	6.302669e-9
GO:0042060	wound healing	6.690419e-9
GO:0002820	negative regulation of adaptive immune response	6.754792e-9
GO:0006887	exocytosis	8.610187e-9
GO:0040012	regulation of locomotion	1.349514e-8
GO:0002378	immunoglobulin biosynthetic process	1.763725e-8
GO:0006904	vesicle docking involved in exocytosis	1.970035e-8
GO:0051704	multi-organism process	1.975126e-8
GO:0018149	peptide cross-linking	2.052570e-8
GO:0006733	oxidoreduction coenzyme metabolic process	2.308910e-8
GO:0022406	membrane docking	2.489242e-8
GO:0006952	defense response	2.590574e-8
GO:0031640	killing of cells of other organism	3.379573e-8
GO:0070541	response to platinum ion	3.419151e-8
GO:0009607	response to biotic stimulus	3.510285e-8
GO:0050900	leukocyte migration	3.652949e-8
GO:0034392	negative regulation of smooth muscle cell apoptosis	4.816337e-8
GO:0015671	oxygen transport	6.913345e-8
GO:0051769	regulation of nitric-oxide synthase biosynthetic process	7.152865e-8
GO:0002710	negative regulation of T cell mediated immunity	8.278692e-8
GO:0032101	regulation of response to external stimulus	9.926348e-8
GO:0001911	negative regulation of leukocyte mediated cytotoxicity	1.204362e-7
GO:0048278	vesicle docking	1.594573e-7
GO:0051607	defense response to virus	1.737669e-7
GO:0019079	viral genome replication	1.938134e-7
GO:0031342	negative regulation of cell killing	2.530538e-7
GO:0007015	actin filament organization	2.877001e-7
GO:0006941	striated muscle contraction	3.116278e-7
GO:0051606	detection of stimulus	3.203422e-7
GO:0007186	G-protein coupled receptor protein signaling pathway	3.218555e-7
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	3.314051e-7
GO:0009441	glycolate metabolic process	3.581346e-7
GO:0050906	detection of stimulus involved in sensory perception	3.678000e-7
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	3.974420e-7
GO:0009605	response to external stimulus	4.027468e-7
GO:0048683	regulation of collateral sprouting of intact axon in response to injury	4.302802e-7
GO:0006928	cellular component movement	4.591585e-7
GO:0030595	leukocyte chemotaxis	4.758112e-7
GO:0032940	secretion by cell	4.996467e-7
GO:0031100	organ regeneration	5.777736e-7
GO:0048869	cellular developmental process	6.569085e-7
GO:0072358	cardiovascular system development	6.776903e-7
GO:2000145	regulation of cell motility	7.669755e-7
GO:0030154	cell differentiation	8.784487e-7
GO:0070208	protein heterotrimerization	9.297725e-7
GO:0009887	organ morphogenesis	1.058400e-6
GO:0045444	fat cell differentiation	1.060857e-6
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	1.080087e-6
GO:0001101	response to acid	1.106733e-6
GO:0051270	regulation of cellular component movement	1.172572e-6
GO:0033211	adiponectin-mediated signaling pathway	1.218451e-6
GO:0033059	cellular pigmentation	1.247382e-6
GO:0014904	myotube cell development	1.251345e-6
GO:0007270	neuron-neuron synaptic transmission	1.288297e-6
GO:0043200	response to amino acid stimulus	1.371555e-6
GO:0002576	platelet degranulation	1.406656e-6
GO:0009167	purine ribonucleoside monophosphate metabolic process	1.427271e-6
GO:0051974	negative regulation of telomerase activity	1.479315e-6
GO:0002520	immune system development	1.512797e-6
GO:0001775	cell activation	1.594085e-6
GO:0040007	growth	1.688770e-6
GO:0070206	protein trimerization	1.693243e-6
GO:0001543	ovarian follicle rupture	1.698995e-6
GO:0001914	regulation of T cell mediated cytotoxicity	1.708133e-6
GO:0048713	regulation of oligodendrocyte differentiation	1.759368e-6
GO:0009617	response to bacterium	1.905433e-6
GO:0048662	negative regulation of smooth muscle cell proliferation	1.947741e-6
GO:0032252	secretory granule localization	1.948436e-6
GO:0030258	lipid modification	2.221761e-6
GO:0046903	secretion	2.312347e-6
GO:0016192	vesicle-mediated transport	2.313479e-6
GO:0030334	regulation of cell migration	2.329655e-6
GO:0001906	cell killing	2.689264e-6
GO:0048589	developmental growth	2.702155e-6
GO:0045137	development of primary sexual characteristics	2.742378e-6
GO:0048485	sympathetic nervous system development	3.157480e-6
GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly	3.821907e-6
GO:0048730	epidermis morphogenesis	4.155754e-6
GO:0034115	negative regulation of heterotypic cell-cell adhesion	4.362801e-6
GO:0045022	early endosome to late endosome transport	4.428590e-6
GO:0045685	regulation of glial cell differentiation	4.814603e-6
GO:0051648	vesicle localization	4.815556e-6
GO:0006651	diacylglycerol biosynthetic process	5.096574e-6
GO:0006769	nicotinamide metabolic process	5.215514e-6
GO:0050793	regulation of developmental process	5.738477e-6
GO:0006955	immune response	5.741676e-6
GO:0009156	ribonucleoside monophosphate biosynthetic process	5.881667e-6
GO:0006542	glutamine biosynthetic process	6.032920e-6
GO:0048729	tissue morphogenesis	6.386106e-6
GO:0043473	pigmentation	6.403862e-6
GO:0050777	negative regulation of immune response	6.530423e-6
GO:0006144	purine base metabolic process	6.591040e-6
GO:0018106	peptidyl-histidine phosphorylation	7.998347e-6
GO:0060761	negative regulation of response to cytokine stimulus	8.312973e-6
GO:0048468	cell development	8.342157e-6
GO:0051234	establishment of localization	8.458000e-6
GO:0010656	negative regulation of muscle cell apoptosis	8.605548e-6
GO:0015911	plasma membrane long-chain fatty acid transport	8.664154e-6
GO:0006810	transport	9.744758e-6
GO:0009820	alkaloid metabolic process	9.863218e-6
GO:0009593	detection of chemical stimulus	1.072587e-5
GO:0008406	gonad development	1.074210e-5
GO:0035414	negative regulation of catenin import into nucleus	1.130148e-5
GO:0019935	cyclic-nucleotide-mediated signaling	1.225905e-5
GO:0044030	regulation of DNA methylation	1.318871e-5
GO:0050907	detection of chemical stimulus involved in sensory perception	1.373901e-5
GO:0048583	regulation of response to stimulus	1.422611e-5
GO:0009161	ribonucleoside monophosphate metabolic process	1.462211e-5
GO:0034720	histone H3-K4 demethylation	1.488797e-5
GO:0060008	Sertoli cell differentiation	1.547275e-5
GO:0048534	hemopoietic or lymphoid organ development	1.614341e-5
GO:0006959	humoral immune response	1.615072e-5
GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	1.639205e-5
GO:0003009	skeletal muscle contraction	1.721599e-5
GO:0002682	regulation of immune system process	1.953606e-5
GO:0060027	convergent extension involved in gastrulation	2.057639e-5
GO:0007181	transforming growth factor beta receptor complex assembly	2.249293e-5
GO:0010033	response to organic substance	2.533663e-5
GO:0030318	melanocyte differentiation	2.547556e-5
GO:0060137	maternal process involved in parturition	2.557975e-5
GO:0090370	negative regulation of cholesterol efflux	2.607913e-5
GO:0003012	muscle system process	2.681488e-5
GO:0030168	platelet activation	2.691572e-5
GO:0019585	glucuronate metabolic process	2.715737e-5
GO:0035630	bone mineralization involved in bone maturation	2.821939e-5
GO:0070098	chemokine-mediated signaling pathway	2.980491e-5
GO:0030097	hemopoiesis	2.994714e-5
GO:0006936	muscle contraction	3.114446e-5
GO:0014075	response to amine stimulus	3.177808e-5
GO:0043615	astrocyte cell migration	3.179701e-5
GO:0001960	negative regulation of cytokine-mediated signaling pathway	3.303101e-5
GO:0002377	immunoglobulin production	3.341732e-5
GO:0043201	response to leucine	3.343044e-5
GO:0046834	lipid phosphorylation	3.447869e-5
GO:0043603	cellular amide metabolic process	3.462292e-5
GO:0046854	phosphatidylinositol phosphorylation	3.501469e-5
GO:0010996	response to auditory stimulus	3.683444e-5
GO:0046504	glycerol ether biosynthetic process	3.683566e-5
GO:0050679	positive regulation of epithelial cell proliferation	3.710174e-5
GO:0071219	cellular response to molecule of bacterial origin	3.956514e-5
GO:0051272	positive regulation of cellular component movement	3.974685e-5
GO:0032400	melanosome localization	3.979055e-5
GO:0061039	ovum-producing ovary development	3.999161e-5
GO:0022603	regulation of anatomical structure morphogenesis	4.030546e-5
GO:0032728	positive regulation of interferon-beta production	4.091560e-5
GO:0048245	eosinophil chemotaxis	4.095613e-5
GO:0043163	cell envelope organization	4.135919e-5
GO:0007076	mitotic chromosome condensation	4.185950e-5
GO:0007155	cell adhesion	4.357461e-5
GO:0051877	pigment granule aggregation in cell center	4.422786e-5
GO:0032879	regulation of localization	4.656353e-5
GO:0046545	development of primary female sexual characteristics	4.657088e-5
GO:0014051	gamma-aminobutyric acid secretion	4.661515e-5
GO:0045938	positive regulation of circadian sleep/wake cycle, sleep	4.676129e-5
GO:0009100	glycoprotein metabolic process	5.052541e-5
GO:0035684	helper T cell extravasation	5.059313e-5
GO:0006029	proteoglycan metabolic process	5.136424e-5
GO:0002548	monocyte chemotaxis	5.233011e-5
GO:0010332	response to gamma radiation	5.323616e-5
GO:0071222	cellular response to lipopolysaccharide	5.409866e-5
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	5.587924e-5
GO:0034391	regulation of smooth muscle cell apoptosis	6.402773e-5
GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	6.402773e-5
GO:0050911	detection of chemical stimulus involved in sensory perception of smell	6.446426e-5
GO:0032387	negative regulation of intracellular transport	6.800604e-5
GO:0048247	lymphocyte chemotaxis	6.901922e-5
GO:0009987	cellular process	6.980400e-5
GO:0035412	regulation of catenin import into nucleus	6.982117e-5
GO:0009615	response to virus	7.004003e-5
GO:0060296	regulation of cilium beat frequency involved in ciliary motility	7.073461e-5
GO:0060429	epithelium development	7.393676e-5
GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	7.613096e-5
GO:0050776	regulation of immune response	7.735641e-5
GO:0051641	cellular localization	7.803769e-5
GO:0019932	second-messenger-mediated signaling	7.804051e-5
GO:0030335	positive regulation of cell migration	8.127777e-5
GO:0043129	surfactant homeostasis	8.498022e-5
GO:0007608	sensory perception of smell	8.612993e-5
GO:0001501	skeletal system development	8.700938e-5
GO:0048661	positive regulation of smooth muscle cell proliferation	8.718740e-5
GO:0071221	cellular response to bacterial lipopeptide	8.833859e-5
GO:0060644	mammary gland epithelial cell differentiation	8.838629e-5
GO:0045017	glycerolipid biosynthetic process	8.943129e-5
GO:0046398	UDP-glucuronate metabolic process	8.981743e-5
GO:0030166	proteoglycan biosynthetic process	9.034737e-5
GO:0030858	positive regulation of epithelial cell differentiation	9.296787e-5
GO:0050974	detection of mechanical stimulus involved in sensory perception	9.363560e-5
GO:0090317	negative regulation of intracellular protein transport	9.389740e-5
GO:0030261	chromosome condensation	9.466088e-5
GO:2000147	positive regulation of cell motility	9.486328e-5
GO:0050925	negative regulation of negative chemotaxis	9.615077e-5
GO:0032496	response to lipopolysaccharide	9.854754e-5
GO:0055065	metal ion homeostasis	1.004115e-4
GO:0051875	pigment granule localization	1.005853e-4
GO:0043353	enucleate erythrocyte differentiation	1.006946e-4
GO:0048769	sarcomerogenesis	1.053519e-4
GO:0016998	cell wall macromolecule catabolic process	1.135246e-4
GO:0051196	regulation of coenzyme metabolic process	1.156823e-4
GO:0070936	protein K48-linked ubiquitination	1.173771e-4
GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate	1.176950e-4
GO:0055074	calcium ion homeostasis	1.177603e-4
GO:0070887	cellular response to chemical stimulus	1.179705e-4
GO:0007219	Notch signaling pathway	1.209294e-4
GO:0030155	regulation of cell adhesion	1.227454e-4
GO:0035634	response to stilbenoid	1.239807e-4
GO:0048584	positive regulation of response to stimulus	1.265592e-4
GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	1.274542e-4
GO:0007267	cell-cell signaling	1.303640e-4
GO:0043931	ossification involved in bone maturation	1.315836e-4
GO:0048646	anatomical structure formation involved in morphogenesis	1.317191e-4
GO:0032989	cellular component morphogenesis	1.334765e-4
GO:0002237	response to molecule of bacterial origin	1.348531e-4
GO:0008585	female gonad development	1.395583e-4
GO:0008544	epidermis development	1.403681e-4
GO:0032431	activation of phospholipase A2 activity	1.405007e-4
GO:0048715	negative regulation of oligodendrocyte differentiation	1.405268e-4
GO:0060402	calcium ion transport into cytosol	1.405653e-4
GO:0009108	coenzyme biosynthetic process	1.422937e-4
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	1.468951e-4
GO:0009589	detection of UV	1.468951e-4
GO:0021778	oligodendrocyte cell fate specification	1.475047e-4
GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	1.499217e-4
GO:0060759	regulation of response to cytokine stimulus	1.528311e-4
GO:0006874	cellular calcium ion homeostasis	1.540938e-4
GO:0007584	response to nutrient	1.548156e-4
GO:0010632	regulation of epithelial cell migration	1.585574e-4
GO:0016081	synaptic vesicle docking involved in exocytosis	1.598731e-4
GO:0045597	positive regulation of cell differentiation	1.675944e-4
GO:0007188	G-protein signaling, coupled to cAMP nucleotide second messenger	1.683305e-4
GO:0001963	synaptic transmission, dopaminergic	1.684217e-4
GO:0014047	glutamate secretion	1.702934e-4
GO:0003357	noradrenergic neuron differentiation	1.706509e-4
GO:0050953	sensory perception of light stimulus	1.709249e-4
GO:0006875	cellular metal ion homeostasis	1.719741e-4
GO:0040017	positive regulation of locomotion	1.720580e-4
GO:0032430	positive regulation of phospholipase A2 activity	1.766071e-4
GO:0048246	macrophage chemotaxis	1.799473e-4
GO:0007032	endosome organization	1.823165e-4
GO:0016477	cell migration	1.831585e-4
GO:0050801	ion homeostasis	1.834282e-4
GO:0030240	skeletal muscle thin filament assembly	1.851548e-4
GO:2000279	negative regulation of DNA biosynthetic process	1.914235e-4
GO:0042742	defense response to bacterium	1.961665e-4
GO:0001525	angiogenesis	1.968125e-4
GO:0030036	actin cytoskeleton organization	1.972162e-4
GO:0002440	production of molecular mediator of immune response	2.002935e-4
GO:0044036	cell wall macromolecule metabolic process	2.019342e-4
GO:0090023	positive regulation of neutrophil chemotaxis	2.025654e-4
GO:0051659	maintenance of mitochondrion location	2.072266e-4
GO:0019933	cAMP-mediated signaling	2.086428e-4
GO:2000334	positive regulation of blood microparticle formation	2.097122e-4
GO:0007548	sex differentiation	2.097883e-4
GO:0051883	killing of cells in other organism involved in symbiotic interaction	2.103294e-4
GO:0048791	calcium ion-dependent exocytosis of neurotransmitter	2.165523e-4
GO:0008104	protein localization	2.212569e-4
GO:0045091	regulation of retroviral genome replication	2.225379e-4
GO:0035444	nickel ion transmembrane transport	2.293061e-4
GO:0070627	ferrous iron import	2.293061e-4
GO:0015692	lead ion transport	2.293061e-4
GO:0015676	vanadium ion transport	2.293061e-4
GO:0006650	glycerophospholipid metabolic process	2.320029e-4
GO:0001944	vasculature development	2.340670e-4
GO:0070886	positive regulation of calcineurin-NFAT signaling pathway	2.351931e-4
GO:0015868	purine ribonucleotide transport	2.364577e-4
GO:0042178	xenobiotic catabolic process	2.390033e-4
GO:0008284	positive regulation of cell proliferation	2.410068e-4
GO:0042127	regulation of cell proliferation	2.446825e-4
GO:0090265	positive regulation of immune complex clearance by monocytes and macrophages	2.454272e-4
GO:0050877	neurological system process	2.469333e-4
GO:0010259	multicellular organismal aging	2.472414e-4
GO:0010810	regulation of cell-substrate adhesion	2.532521e-4
GO:0030182	neuron differentiation	2.569562e-4
GO:0060081	membrane hyperpolarization	2.620812e-4
GO:0000904	cell morphogenesis involved in differentiation	2.624324e-4
GO:0071216	cellular response to biotic stimulus	2.627410e-4
GO:0072503	cellular divalent inorganic cation homeostasis	2.640438e-4
GO:0002320	lymphoid progenitor cell differentiation	2.690272e-4
GO:0070094	positive regulation of glucagon secretion	2.800958e-4
GO:0008038	neuron recognition	2.802036e-4
GO:0048732	gland development	2.837667e-4
GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger	2.848408e-4
GO:0002684	positive regulation of immune system process	2.850174e-4
GO:0050931	pigment cell differentiation	2.858920e-4
GO:0006541	glutamine metabolic process	2.892695e-4
GO:0033034	positive regulation of myeloid cell apoptosis	2.960685e-4
GO:0042180	cellular ketone metabolic process	2.969561e-4
GO:0032648	regulation of interferon-beta production	3.001011e-4
GO:0001959	regulation of cytokine-mediated signaling pathway	3.001846e-4
GO:0000819	sister chromatid segregation	3.043963e-4
GO:0001932	regulation of protein phosphorylation	3.072138e-4
GO:2000178	negative regulation of neural precursor cell proliferation	3.145341e-4
GO:0043252	sodium-independent organic anion transport	3.151908e-4
GO:0046823	negative regulation of nucleocytoplasmic transport	3.157929e-4
GO:0048483	autonomic nervous system development	3.230706e-4
GO:0007601	visual perception	3.296575e-4
GO:0007018	microtubule-based movement	3.312625e-4
GO:0051640	organelle localization	3.327345e-4
GO:0033144	negative regulation of steroid hormone receptor signaling pathway	3.425688e-4
GO:0046108	uridine metabolic process	3.441588e-4
GO:0001502	cartilage condensation	3.475438e-4
GO:0042402	cellular biogenic amine catabolic process	3.493273e-4
GO:0000070	mitotic sister chromatid segregation	3.497979e-4
GO:0019836	hemolysis by symbiont of host erythrocytes	3.520187e-4
GO:0034201	response to oleic acid	3.544426e-4
GO:0014834	satellite cell maintenance involved in skeletal muscle regeneration	3.560187e-4
GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development	3.615635e-4
GO:0051646	mitochondrion localization	3.705626e-4
GO:0072507	divalent inorganic cation homeostasis	3.707537e-4
GO:0006954	inflammatory response	3.812759e-4
GO:0055080	cation homeostasis	3.846015e-4
GO:0045665	negative regulation of neuron differentiation	3.851698e-4
GO:0050881	musculoskeletal movement	3.864011e-4
GO:0032402	melanosome transport	3.892369e-4
GO:0015812	gamma-aminobutyric acid transport	3.912754e-4
GO:0006811	ion transport	3.921723e-4
GO:0051970	negative regulation of transmission of nerve impulse	4.137223e-4
GO:0019752	carboxylic acid metabolic process	4.171402e-4
GO:0032481	positive regulation of type I interferon production	4.232670e-4
GO:0030198	extracellular matrix organization	4.479744e-4
GO:0060632	regulation of microtubule-based movement	4.503345e-4
GO:0090022	regulation of neutrophil chemotaxis	4.612245e-4
GO:0048870	cell motility	4.668150e-4
GO:0051094	positive regulation of developmental process	4.681196e-4
GO:0030029	actin filament-based process	4.689923e-4
GO:0010720	positive regulation of cell development	4.722238e-4
GO:0010613	positive regulation of cardiac muscle hypertrophy	4.757840e-4
GO:0032274	gonadotropin secretion	4.765529e-4
GO:0048644	muscle organ morphogenesis	4.783675e-4
GO:0051188	cofactor biosynthetic process	4.936990e-4
GO:0000902	cell morphogenesis	5.155638e-4
GO:0045590	negative regulation of regulatory T cell differentiation	5.332757e-4
GO:0002707	negative regulation of lymphocyte mediated immunity	5.398968e-4
GO:0050878	regulation of body fluid levels	5.730968e-4
GO:0006732	coenzyme metabolic process	5.750432e-4
GO:0009101	glycoprotein biosynthetic process	5.865790e-4
GO:0043623	cellular protein complex assembly	5.874719e-4
GO:0051216	cartilage development	5.954479e-4
GO:0043046	DNA methylation involved in gamete generation	5.988752e-4
GO:0046826	negative regulation of protein export from nucleus	5.988752e-4
GO:0007399	nervous system development	6.021387e-4
GO:0035510	DNA dealkylation	6.060576e-4
GO:0046486	glycerolipid metabolic process	6.091204e-4
GO:0071840	cellular component organization or biogenesis	6.101923e-4
GO:0007530	sex determination	6.108031e-4
GO:0060401	cytosolic calcium ion transport	6.124975e-4
GO:0051041	positive regulation of calcium-independent cell-cell adhesion	6.183111e-4
GO:0050902	leukocyte adhesive activation	6.183111e-4
GO:0048608	reproductive structure development	6.270153e-4
GO:0001910	regulation of leukocyte mediated cytotoxicity	6.299750e-4
GO:0045663	positive regulation of myoblast differentiation	6.376673e-4
GO:0006935	chemotaxis	6.439388e-4
GO:0002328	pro-B cell differentiation	6.508285e-4
GO:2000481	positive regulation of cAMP-dependent protein kinase activity	6.546501e-4
GO:2000534	positive regulation of renal albumin absorption	6.546501e-4
GO:2000461	negative regulation of eukaryotic cell surface binding	6.546501e-4
GO:2000478	positive regulation of metanephric glomerular visceral epithelial cell development	6.546501e-4
GO:0070994	detection of oxidative stress	6.546501e-4
GO:0071447	cellular response to hydroperoxide	6.662212e-4
GO:0048585	negative regulation of response to stimulus	6.737150e-4
GO:0021794	thalamus development	6.821779e-4
GO:0007596	blood coagulation	6.878971e-4
GO:0006175	dATP biosynthetic process	6.901112e-4
GO:0018202	peptidyl-histidine modification	6.974865e-4
GO:0019441	tryptophan catabolic process to kynurenine	6.984192e-4
GO:0042325	regulation of phosphorylation	7.039918e-4
GO:0003289	atrial septum primum morphogenesis	7.219413e-4
GO:0006082	organic acid metabolic process	7.234111e-4
GO:0040011	locomotion	7.256098e-4
GO:0031214	biomineral tissue development	7.364004e-4
GO:0048670	regulation of collateral sprouting	7.368420e-4
GO:0001568	blood vessel development	7.518184e-4
GO:0032854	positive regulation of Rap GTPase activity	7.594064e-4
GO:0032878	regulation of establishment or maintenance of cell polarity	7.765102e-4
GO:0045069	regulation of viral genome replication	7.780002e-4
GO:0046463	acylglycerol biosynthetic process	7.790517e-4
GO:0048549	positive regulation of pinocytosis	7.969166e-4
GO:0051239	regulation of multicellular organismal process	8.172658e-4
GO:0014912	negative regulation of smooth muscle cell migration	8.262802e-4
GO:0043420	anthranilate metabolic process	8.365103e-4
GO:0034516	response to vitamin B6	8.365103e-4
GO:0009581	detection of external stimulus	8.401080e-4
GO:0070373	negative regulation of ERK1 and ERK2 cascade	8.458674e-4
GO:0033157	regulation of intracellular protein transport	8.490241e-4
GO:0008037	cell recognition	8.521737e-4
GO:0070184	mitochondrial tyrosyl-tRNA aminoacylation	8.595391e-4
GO:0046660	female sex differentiation	8.606675e-4
GO:0042246	tissue regeneration	8.628980e-4
GO:0007599	hemostasis	8.711704e-4
GO:0009750	response to fructose stimulus	8.743350e-4
GO:0050805	negative regulation of synaptic transmission	8.998739e-4
GO:0031349	positive regulation of defense response	9.036130e-4
GO:0060326	cell chemotaxis	9.048915e-4
GO:0007179	transforming growth factor beta receptor signaling pathway	9.170559e-4
GO:0065008	regulation of biological quality	9.400422e-4
GO:0007409	axonogenesis	9.479753e-4
GO:0051186	cofactor metabolic process	9.561421e-4
GO:0046884	follicle-stimulating hormone secretion	9.625130e-4
GO:0032275	luteinizing hormone secretion	9.625130e-4
GO:0051904	pigment granule transport	9.838912e-4
GO:0030879	mammary gland development	9.861211e-4
GO:0010811	positive regulation of cell-substrate adhesion	9.936132e-4
GO:0055082	cellular chemical homeostasis	9.955856e-4
GO:0006873	cellular ion homeostasis	1.031172e-3
GO:0071229	cellular response to acid	1.041143e-3
GO:0032509	endosome transport via multivesicular body sorting pathway	1.044704e-3
GO:0060100	positive regulation of phagocytosis, engulfment	1.046005e-3
GO:0001666	response to hypoxia	1.052025e-3
GO:0051972	regulation of telomerase activity	1.057734e-3
GO:0060716	labyrinthine layer blood vessel development	1.061921e-3
GO:0051017	actin filament bundle assembly	1.062316e-3
GO:0051893	regulation of focal adhesion assembly	1.074294e-3
GO:0002690	positive regulation of leukocyte chemotaxis	1.096052e-3
GO:0000910	cytokinesis	1.096052e-3
GO:0090082	positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway	1.099072e-3
GO:0048519	negative regulation of biological process	1.105584e-3
GO:0032787	monocarboxylic acid metabolic process	1.116910e-3
GO:0007606	sensory perception of chemical stimulus	1.120022e-3
GO:0051155	positive regulation of striated muscle cell differentiation	1.145191e-3
GO:0007412	axon target recognition	1.145768e-3
GO:0032429	regulation of phospholipase A2 activity	1.150702e-3
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	1.154014e-3
GO:0019915	lipid storage	1.157230e-3
GO:0032990	cell part morphogenesis	1.165353e-3
GO:0006214	thymidine catabolic process	1.177659e-3
GO:0050654	chondroitin sulfate proteoglycan metabolic process	1.178329e-3
GO:0048666	neuron development	1.191866e-3
GO:0021761	limbic system development	1.194821e-3
GO:0043949	regulation of cAMP-mediated signaling	1.199055e-3
GO:0021779	oligodendrocyte cell fate commitment	1.199375e-3
GO:0032886	regulation of microtubule-based process	1.206890e-3
GO:0010243	response to organic nitrogen	1.222805e-3
GO:0060986	endocrine hormone secretion	1.234995e-3
GO:0043409	negative regulation of MAPKKK cascade	1.287705e-3
GO:0016198	axon choice point recognition	1.294328e-3
GO:0019442	tryptophan catabolic process to acetyl-CoA	1.296954e-3
GO:0051025	negative regulation of immunoglobulin secretion	1.299730e-3
GO:0021941	negative regulation of cerebellar granule cell precursor proliferation	1.299730e-3
GO:0033182	regulation of histone ubiquitination	1.299730e-3
GO:0045214	sarcomere organization	1.322574e-3
GO:0016043	cellular component organization	1.340636e-3
GO:0050920	regulation of chemotaxis	1.340768e-3
GO:0048812	neuron projection morphogenesis	1.343082e-3
GO:0090310	negative regulation of methylation-dependent chromatin silencing	1.366620e-3
GO:0001952	regulation of cell-matrix adhesion	1.367109e-3
GO:0051149	positive regulation of muscle cell differentiation	1.373324e-3
GO:0023057	negative regulation of signaling	1.377554e-3
GO:0060166	olfactory pit development	1.390532e-3
GO:0007204	elevation of cytosolic calcium ion concentration	1.418830e-3
GO:2000121	regulation of removal of superoxide radicals	1.422570e-3
GO:0010648	negative regulation of cell communication	1.425802e-3
GO:0021854	hypothalamus development	1.429157e-3
GO:0048878	chemical homeostasis	1.429234e-3
GO:0030104	water homeostasis	1.434706e-3
GO:0050982	detection of mechanical stimulus	1.443309e-3
GO:0070371	ERK1 and ERK2 cascade	1.450922e-3
GO:0007517	muscle organ development	1.455164e-3
GO:0048518	positive regulation of biological process	1.461791e-3
GO:0030252	growth hormone secretion	1.463924e-3
GO:0030728	ovulation	1.489702e-3
GO:0050923	regulation of negative chemotaxis	1.499029e-3
GO:0061013	regulation of mRNA catabolic process	1.502955e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0007166	cell surface receptor linked signaling pathway	4.569610e-14
GO:0014904	myotube cell development	9.111034e-14
GO:0050654	chondroitin sulfate proteoglycan metabolic process	7.692125e-13
GO:0045821	positive regulation of glycolysis	3.085198e-12
GO:0060741	prostate gland stromal morphogenesis	6.739386e-12
GO:0035630	bone mineralization involved in bone maturation	1.058489e-11
GO:0006029	proteoglycan metabolic process	9.349565e-11
GO:0006110	regulation of glycolysis	1.117377e-10
GO:0043931	ossification involved in bone maturation	1.711133e-10
GO:0014834	satellite cell maintenance involved in skeletal muscle regeneration	2.465556e-10
GO:0070977	bone maturation	6.617144e-10
GO:0034392	negative regulation of smooth muscle cell apoptosis	1.435245e-9
GO:0060766	negative regulation of androgen receptor signaling pathway	3.414125e-9
GO:2000179	positive regulation of neural precursor cell proliferation	4.729996e-9
GO:0050896	response to stimulus	7.722131e-9
GO:0048009	insulin-like growth factor receptor signaling pathway	1.175366e-8
GO:0042129	regulation of T cell proliferation	1.297142e-8
GO:0014896	muscle hypertrophy	1.346446e-8
GO:0050863	regulation of T cell activation	1.722624e-8
GO:0032878	regulation of establishment or maintenance of cell polarity	1.820097e-8
GO:0043519	regulation of myosin II filament organization	1.867208e-8
GO:0048608	reproductive structure development	2.188626e-8
GO:0034391	regulation of smooth muscle cell apoptosis	2.471242e-8
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	3.283123e-8
GO:0090201	negative regulation of release of cytochrome c from mitochondria	3.328277e-8
GO:0060527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	3.484123e-8
GO:0048015	phosphatidylinositol-mediated signaling	3.957750e-8
GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein	4.153744e-8
GO:0045445	myoblast differentiation	4.482083e-8
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	4.608592e-8
GO:0009100	glycoprotein metabolic process	5.273009e-8
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	5.674909e-8
GO:0010823	negative regulation of mitochondrion organization	5.913454e-8
GO:0060271	cilium morphogenesis	8.119285e-8
GO:0002768	immune response-regulating cell surface receptor signaling pathway	9.533093e-8
GO:0043471	regulation of cellular carbohydrate catabolic process	1.164683e-7
GO:0097113	alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering	1.325524e-7
GO:0014066	regulation of phosphatidylinositol 3-kinase cascade	2.005062e-7
GO:0060509	Type I pneumocyte differentiation	2.045631e-7
GO:0010592	positive regulation of lamellipodium assembly	2.460493e-7
GO:0003008	system process	2.574168e-7
GO:0051491	positive regulation of filopodium assembly	2.658949e-7
GO:0048856	anatomical structure development	2.797625e-7
GO:0033144	negative regulation of steroid hormone receptor signaling pathway	3.058550e-7
GO:0002764	immune response-regulating signaling pathway	3.328032e-7
GO:0051489	regulation of filopodium assembly	3.428316e-7
GO:0032501	multicellular organismal process	4.243270e-7
GO:0030850	prostate gland development	4.257494e-7
GO:0040014	regulation of multicellular organism growth	4.459909e-7
GO:0035019	somatic stem cell maintenance	5.117776e-7
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	5.319682e-7
GO:0019827	stem cell maintenance	5.606490e-7
GO:0043409	negative regulation of MAPKKK cascade	8.498497e-7
GO:0051057	positive regulation of small GTPase mediated signal transduction	9.065036e-7
GO:0060736	prostate gland growth	9.555598e-7
GO:0030593	neutrophil chemotaxis	9.786592e-7
GO:0051450	myoblast proliferation	9.791583e-7
GO:0060463	lung lobe morphogenesis	1.026255e-6
GO:0060740	prostate gland epithelium morphogenesis	1.054566e-6
GO:0051239	regulation of multicellular organismal process	1.078855e-6
GO:0060512	prostate gland morphogenesis	1.259728e-6
GO:0060442	branching involved in prostate gland morphogenesis	1.358315e-6
GO:0060765	regulation of androgen receptor signaling pathway	1.384350e-6
GO:0030166	proteoglycan biosynthetic process	1.551608e-6
GO:0014068	positive regulation of phosphatidylinositol 3-kinase cascade	1.576446e-6
GO:0042522	regulation of tyrosine phosphorylation of Stat5 protein	1.732979e-6
GO:0010656	negative regulation of muscle cell apoptosis	1.732979e-6
GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	1.760972e-6
GO:0002429	immune response-activating cell surface receptor signaling pathway	1.780839e-6
GO:0032765	positive regulation of mast cell cytokine production	1.807089e-6
GO:0002431	Fc receptor mediated stimulatory signaling pathway	1.807089e-6
GO:0014911	positive regulation of smooth muscle cell migration	1.869718e-6
GO:0035264	multicellular organism growth	1.922636e-6
GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	1.935787e-6
GO:0007186	G-protein coupled receptor protein signaling pathway	2.226947e-6
GO:0061033	secretion by lung epithelial cell involved in lung growth	2.312492e-6
GO:0043666	regulation of phosphoprotein phosphatase activity	2.385498e-6
GO:0070663	regulation of leukocyte proliferation	2.443208e-6
GO:0051249	regulation of lymphocyte activation	2.483319e-6
GO:0010660	regulation of muscle cell apoptosis	2.915354e-6
GO:0043408	regulation of MAPKKK cascade	2.953369e-6
GO:0010591	regulation of lamellipodium assembly	3.151122e-6
GO:0009653	anatomical structure morphogenesis	3.314187e-6
GO:0051549	positive regulation of keratinocyte migration	3.431246e-6
GO:0002757	immune response-activating signal transduction	3.438734e-6
GO:0046834	lipid phosphorylation	3.444090e-6
GO:0030204	chondroitin sulfate metabolic process	3.457134e-6
GO:0042102	positive regulation of T cell proliferation	3.580083e-6
GO:0002682	regulation of immune system process	3.656089e-6
GO:0032502	developmental process	3.662947e-6
GO:0050870	positive regulation of T cell activation	3.805789e-6
GO:0030838	positive regulation of actin filament polymerization	3.873353e-6
GO:0043403	skeletal muscle tissue regeneration	4.230278e-6
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	4.321755e-6
GO:0060525	prostate glandular acinus development	4.452428e-6
GO:0044272	sulfur compound biosynthetic process	4.607628e-6
GO:0008284	positive regulation of cell proliferation	5.092414e-6
GO:0002684	positive regulation of immune system process	5.165855e-6
GO:0050670	regulation of lymphocyte proliferation	5.474542e-6
GO:0021936	regulation of cerebellar granule cell precursor proliferation	5.595771e-6
GO:0097115	neurexin clustering	5.917762e-6
GO:0007157	heterophilic cell-cell adhesion	6.050654e-6
GO:0050865	regulation of cell activation	6.084846e-6
GO:0032944	regulation of mononuclear cell proliferation	6.831884e-6
GO:0006629	lipid metabolic process	7.483850e-6
GO:0043488	regulation of mRNA stability	7.913311e-6
GO:0022612	gland morphogenesis	8.203746e-6
GO:0050679	positive regulation of epithelial cell proliferation	8.206189e-6
GO:0045321	leukocyte activation	8.541493e-6
GO:0019220	regulation of phosphate metabolic process	8.984490e-6
GO:0010676	positive regulation of cellular carbohydrate metabolic process	9.171273e-6
GO:0048583	regulation of response to stimulus	9.281159e-6
GO:0060437	lung growth	9.294888e-6
GO:0006888	ER to Golgi vesicle-mediated transport	9.595405e-6
GO:0048731	system development	1.050283e-5
GO:0002694	regulation of leukocyte activation	1.071296e-5
GO:0021940	positive regulation of cerebellar granule cell precursor proliferation	1.071568e-5
GO:0070934	CRD-mediated mRNA stabilization	1.172111e-5
GO:0022610	biological adhesion	1.195131e-5
GO:0060009	Sertoli cell development	1.256535e-5
GO:0002819	regulation of adaptive immune response	1.286866e-5
GO:0033043	regulation of organelle organization	1.297323e-5
GO:0023052	signaling	1.351589e-5
GO:0048864	stem cell development	1.407729e-5
GO:0046485	ether lipid metabolic process	1.479030e-5
GO:0046579	positive regulation of Ras protein signal transduction	1.526318e-5
GO:0043487	regulation of RNA stability	1.536178e-5
GO:0046854	phosphatidylinositol phosphorylation	1.571567e-5
GO:0042221	response to chemical stimulus	1.674663e-5
GO:0010907	positive regulation of glucose metabolic process	1.729757e-5
GO:0007155	cell adhesion	1.739609e-5
GO:0002709	regulation of T cell mediated immunity	1.760418e-5
GO:0051493	regulation of cytoskeleton organization	1.799068e-5
GO:0002762	negative regulation of myeloid leukocyte differentiation	1.829306e-5
GO:0045137	development of primary sexual characteristics	2.045121e-5
GO:0007275	multicellular organismal development	2.055919e-5
GO:0009101	glycoprotein biosynthetic process	2.088646e-5
GO:0010675	regulation of cellular carbohydrate metabolic process	2.098342e-5
GO:0006790	sulfur compound metabolic process	2.122203e-5
GO:0045776	negative regulation of blood pressure	2.128137e-5
GO:0048869	cellular developmental process	2.149540e-5
GO:0032656	regulation of interleukin-13 production	2.156986e-5
GO:0030855	epithelial cell differentiation	2.373490e-5
GO:0030203	glycosaminoglycan metabolic process	2.463981e-5
GO:0006109	regulation of carbohydrate metabolic process	2.631708e-5
GO:0046486	glycerolipid metabolic process	2.656493e-5
GO:0016337	cell-cell adhesion	2.672285e-5
GO:0032273	positive regulation of protein polymerization	2.985150e-5
GO:0000245	spliceosome assembly	3.023137e-5
GO:0048513	organ development	3.024312e-5
GO:0060426	lung vasculature development	3.384820e-5
GO:0060008	Sertoli cell differentiation	3.408284e-5
GO:0006022	aminoglycan metabolic process	3.419435e-5
GO:0042509	regulation of tyrosine phosphorylation of STAT protein	3.531918e-5
GO:0035272	exocrine system development	3.608316e-5
GO:0060491	regulation of cell projection assembly	3.649801e-5
GO:0001101	response to acid	3.853502e-5
GO:2000177	regulation of neural precursor cell proliferation	3.888386e-5
GO:0050851	antigen receptor-mediated signaling pathway	4.243206e-5
GO:0010921	regulation of phosphatase activity	4.297330e-5
GO:0010459	negative regulation of heart rate	4.446440e-5
GO:0030104	water homeostasis	4.457426e-5
GO:0072362	regulation of glycolysis by negative regulation of transcription from RNA polymerase II promoter	4.630462e-5
GO:0072368	regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter	4.630462e-5
GO:0051531	NFAT protein import into nucleus	4.808237e-5
GO:0009888	tissue development	4.914121e-5
GO:0010838	positive regulation of keratinocyte proliferation	5.119032e-5
GO:0050868	negative regulation of T cell activation	5.245648e-5
GO:0097120	receptor localization to synapse	5.713780e-5
GO:0072578	neurotransmitter-gated ion channel clustering	5.713780e-5
GO:0002561	basophil degranulation	5.840810e-5
GO:0065007	biological regulation	6.276767e-5
GO:0007167	enzyme linked receptor protein signaling pathway	6.530094e-5
GO:0007154	cell communication	6.690951e-5
GO:0033143	regulation of steroid hormone receptor signaling pathway	6.699499e-5
GO:0006367	transcription initiation from RNA polymerase II promoter	6.735923e-5
GO:0050867	positive regulation of cell activation	7.120598e-5
GO:0031099	regeneration	7.393229e-5
GO:0010638	positive regulation of organelle organization	7.713437e-5
GO:0010040	response to iron(II) ion	7.737313e-5
GO:0045671	negative regulation of osteoclast differentiation	8.020925e-5
GO:0008406	gonad development	8.122893e-5
GO:0043129	surfactant homeostasis	8.147963e-5
GO:0042246	tissue regeneration	8.372056e-5
GO:0045666	positive regulation of neuron differentiation	8.396401e-5
GO:0051495	positive regulation of cytoskeleton organization	8.396401e-5
GO:0048863	stem cell differentiation	8.406487e-5
GO:0070373	negative regulation of ERK1 and ERK2 cascade	8.606862e-5
GO:0001812	positive regulation of type I hypersensitivity	9.048018e-5
GO:0050794	regulation of cellular process	9.056567e-5
GO:0030154	cell differentiation	9.565487e-5
GO:0050776	regulation of immune response	9.882386e-5
GO:0046427	positive regulation of JAK-STAT cascade	1.018966e-4
GO:0007548	sex differentiation	1.047033e-4
GO:0042127	regulation of cell proliferation	1.106641e-4
GO:0090199	regulation of release of cytochrome c from mitochondria	1.122080e-4
GO:0003013	circulatory system process	1.130170e-4
GO:0014902	myotube differentiation	1.137217e-4
GO:0010627	regulation of intracellular protein kinase cascade	1.153975e-4
GO:0002706	regulation of lymphocyte mediated immunity	1.167724e-4
GO:0022008	neurogenesis	1.171806e-4
GO:0006067	ethanol metabolic process	1.189784e-4
GO:0030030	cell projection organization	1.293797e-4
GO:0006376	mRNA splice site selection	1.298602e-4
GO:0045575	basophil activation	1.313700e-4
GO:0022400	regulation of rhodopsin mediated signaling pathway	1.313700e-4
GO:0051250	negative regulation of lymphocyte activation	1.349327e-4
GO:0033026	negative regulation of mast cell apoptosis	1.373721e-4
GO:0001763	morphogenesis of a branching structure	1.433546e-4
GO:0008593	regulation of Notch signaling pathway	1.443360e-4
GO:0050789	regulation of biological process	1.521450e-4
GO:0010716	negative regulation of extracellular matrix disassembly	1.543512e-4
GO:0007165	signal transduction	1.605227e-4
GO:0016071	mRNA metabolic process	1.642128e-4
GO:0035914	skeletal muscle cell differentiation	1.670727e-4
GO:0003006	developmental process involved in reproduction	1.676989e-4
GO:0070665	positive regulation of leukocyte proliferation	1.694330e-4
GO:0001934	positive regulation of protein phosphorylation	1.784005e-4
GO:0050671	positive regulation of lymphocyte proliferation	1.785816e-4
GO:0060042	retina morphogenesis in camera-type eye	1.832514e-4
GO:0030282	bone mineralization	1.844676e-4
GO:0050678	regulation of epithelial cell proliferation	1.852124e-4
GO:0046903	secretion	1.872532e-4
GO:0031017	exocrine pancreas development	1.961661e-4
GO:0042325	regulation of phosphorylation	1.970318e-4
GO:0002696	positive regulation of leukocyte activation	2.023470e-4
GO:0000902	cell morphogenesis	2.110701e-4
GO:0030258	lipid modification	2.132687e-4
GO:0046649	lymphocyte activation	2.151423e-4
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	2.184950e-4
GO:0032946	positive regulation of mononuclear cell proliferation	2.213848e-4
GO:0001941	postsynaptic membrane organization	2.259008e-4
GO:0043200	response to amino acid stimulus	2.305076e-4
GO:0001775	cell activation	2.365060e-4
GO:0000398	nuclear mRNA splicing, via spliceosome	2.464659e-4
GO:0065008	regulation of biological quality	2.476853e-4
GO:0006054	N-acetylneuraminate metabolic process	2.500362e-4
GO:0051241	negative regulation of multicellular organismal process	2.531673e-4
GO:0019227	neuronal action potential propagation	2.540225e-4
GO:0032271	regulation of protein polymerization	2.557440e-4
GO:0010906	regulation of glucose metabolic process	2.791724e-4
GO:0032763	regulation of mast cell cytokine production	2.935460e-4
GO:0006352	transcription initiation, DNA-dependent	2.952661e-4
GO:0048858	cell projection morphogenesis	3.163787e-4
GO:0016080	synaptic vesicle targeting	3.248407e-4
GO:0048732	gland development	3.251855e-4
GO:0032989	cellular component morphogenesis	3.289701e-4
GO:0010740	positive regulation of intracellular protein kinase cascade	3.371078e-4
GO:0006656	phosphatidylcholine biosynthetic process	3.385297e-4
GO:0060479	lung cell differentiation	3.437532e-4
GO:0001974	blood vessel remodeling	3.446336e-4
GO:0051234	establishment of localization	3.454498e-4
GO:0033025	regulation of mast cell apoptosis	3.669311e-4
GO:0051251	positive regulation of lymphocyte activation	3.694491e-4
GO:0045663	positive regulation of myoblast differentiation	3.724863e-4
GO:0030858	positive regulation of epithelial cell differentiation	3.837319e-4
GO:0010625	positive regulation of Schwann cell proliferation	3.884809e-4
GO:0071398	cellular response to fatty acid	3.885552e-4
GO:0035418	protein localization to synapse	3.932161e-4
GO:0010837	regulation of keratinocyte proliferation	4.108561e-4
GO:0005976	polysaccharide metabolic process	4.116178e-4
GO:0070206	protein trimerization	4.150530e-4
GO:0043306	positive regulation of mast cell degranulation	4.433857e-4
GO:0019543	propionate catabolic process	4.440502e-4
GO:0090310	negative regulation of methylation-dependent chromatin silencing	4.440502e-4
GO:0030183	B cell differentiation	4.538813e-4
GO:0002703	regulation of leukocyte mediated immunity	4.621131e-4
GO:0050852	T cell receptor signaling pathway	4.732632e-4
GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	4.746281e-4
GO:0001810	regulation of type I hypersensitivity	4.796439e-4
GO:0001805	positive regulation of type III hypersensitivity	4.796439e-4
GO:0000375	RNA splicing, via transesterification reactions	4.956091e-4
GO:0031399	regulation of protein modification process	5.028074e-4
GO:0016339	calcium-dependent cell-cell adhesion	5.108372e-4
GO:0003018	vascular process in circulatory system	5.124760e-4
GO:0031110	regulation of microtubule polymerization or depolymerization	5.144500e-4
GO:0032990	cell part morphogenesis	5.165227e-4
GO:0030098	lymphocyte differentiation	5.350510e-4
GO:0060695	negative regulation of cholesterol transporter activity	5.440156e-4
GO:0015759	beta-glucoside transport	5.440156e-4
GO:0002033	vasodilation by angiotensin involved in regulation of systemic arterial blood pressure	5.440156e-4
GO:0033033	negative regulation of myeloid cell apoptosis	5.441946e-4
GO:0007605	sensory perception of sound	5.542430e-4
GO:0007160	cell-matrix adhesion	5.615126e-4
GO:0001932	regulation of protein phosphorylation	5.690578e-4
GO:0002376	immune system process	5.804273e-4
GO:0031111	negative regulation of microtubule polymerization or depolymerization	5.856344e-4
GO:0010639	negative regulation of organelle organization	6.114448e-4
GO:0010741	negative regulation of intracellular protein kinase cascade	6.114875e-4
GO:0006040	amino sugar metabolic process	6.360665e-4
GO:0061138	morphogenesis of a branching epithelium	6.409698e-4
GO:0005975	carbohydrate metabolic process	6.662377e-4
GO:0006650	glycerophospholipid metabolic process	6.740546e-4
GO:0002521	leukocyte differentiation	6.835842e-4
GO:0060510	Type II pneumocyte differentiation	6.947173e-4
GO:0006903	vesicle targeting	6.947173e-4
GO:0045767	regulation of anti-apoptosis	6.951702e-4
GO:0070060	'de novo' actin filament nucleation	7.062232e-4
GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	7.091574e-4
GO:0048660	regulation of smooth muscle cell proliferation	7.160369e-4
GO:0051149	positive regulation of muscle cell differentiation	7.403761e-4
GO:0042327	positive regulation of phosphorylation	7.445335e-4
GO:0042592	homeostatic process	7.476874e-4
GO:0043302	positive regulation of leukocyte degranulation	7.498346e-4
GO:0010821	regulation of mitochondrion organization	7.542697e-4
GO:0006810	transport	7.598444e-4
GO:0032673	regulation of interleukin-4 production	7.598796e-4
GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity	7.608669e-4
GO:0008015	blood circulation	8.093870e-4
GO:0032940	secretion by cell	8.110939e-4
GO:0048745	smooth muscle tissue development	8.256437e-4
GO:0050866	negative regulation of cell activation	8.404878e-4
GO:0008016	regulation of heart contraction	8.614171e-4
GO:2000320	negative regulation of T-helper 17 cell differentiation	8.648664e-4
GO:0045017	glycerolipid biosynthetic process	8.649913e-4
GO:0060487	lung epithelial cell differentiation	8.765422e-4
GO:0050849	negative regulation of calcium-mediated signaling	9.012523e-4
GO:0019541	propionate metabolic process	9.012523e-4
GO:0048468	cell development	9.036829e-4
GO:0002695	negative regulation of leukocyte activation	9.138285e-4
GO:0001655	urogenital system development	9.200698e-4
GO:0044057	regulation of system process	9.346434e-4
GO:0015937	coenzyme A biosynthetic process	9.392368e-4
GO:0014910	regulation of smooth muscle cell migration	9.465383e-4
GO:0051716	cellular response to stimulus	9.527682e-4
GO:0048585	negative regulation of response to stimulus	9.622342e-4
GO:0010039	response to iron ion	9.796914e-4
GO:0051650	establishment of vesicle localization	9.796914e-4
GO:0060693	regulation of branching involved in salivary gland morphogenesis	9.872825e-4
GO:0071460	cellular response to cell-matrix adhesion	9.892323e-4
GO:0080134	regulation of response to stress	9.895674e-4
GO:0045840	positive regulation of mitosis	1.032396e-3
GO:0042130	negative regulation of T cell proliferation	1.032396e-3
GO:0001953	negative regulation of cell-matrix adhesion	1.058336e-3
GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	1.070009e-3
GO:0070372	regulation of ERK1 and ERK2 cascade	1.080343e-3
GO:0048699	generation of neurons	1.081851e-3
GO:0046634	regulation of alpha-beta T cell activation	1.104085e-3
GO:0006398	histone mRNA 3'-end processing	1.114653e-3
GO:0002034	regulation of blood vessel size by renin-angiotensin	1.114653e-3
GO:0060537	muscle tissue development	1.163096e-3
GO:0051580	regulation of neurotransmitter uptake	1.165550e-3
GO:0016554	cytidine to uridine editing	1.203796e-3
GO:0007026	negative regulation of microtubule depolymerization	1.211116e-3
GO:0032689	negative regulation of interferon-gamma production	1.229096e-3
GO:0071378	cellular response to growth hormone stimulus	1.229744e-3
GO:0042113	B cell activation	1.243263e-3
GO:0051971	positive regulation of transmission of nerve impulse	1.245840e-3
GO:0031281	positive regulation of cyclase activity	1.247610e-3
GO:0045725	positive regulation of glycogen biosynthetic process	1.266961e-3
GO:0070327	thyroid hormone transport	1.278612e-3
GO:0050973	detection of mechanical stimulus involved in equilibrioception	1.278612e-3
GO:0018149	peptide cross-linking	1.281544e-3
GO:0097105	presynaptic membrane assembly	1.290726e-3
GO:0042946	glucoside transport	1.292706e-3
GO:0050880	regulation of blood vessel size	1.298147e-3
GO:0048871	multicellular organismal homeostasis	1.307528e-3
GO:0046636	negative regulation of alpha-beta T cell activation	1.328356e-3
GO:0051897	positive regulation of protein kinase B signaling cascade	1.338258e-3
GO:0035150	regulation of tube size	1.338258e-3
GO:0043255	regulation of carbohydrate biosynthetic process	1.377102e-3
GO:0048255	mRNA stabilization	1.406927e-3
GO:0050954	sensory perception of mechanical stimulus	1.422538e-3
GO:0050775	positive regulation of dendrite morphogenesis	1.427307e-3
GO:0060425	lung morphogenesis	1.430236e-3
GO:0030036	actin cytoskeleton organization	1.432027e-3
GO:2000505	regulation of energy homeostasis	1.444589e-3
GO:0050957	equilibrioception	1.445735e-3
GO:0045669	positive regulation of osteoblast differentiation	1.461541e-3
GO:0043467	regulation of generation of precursor metabolites and energy	1.476223e-3
GO:0044255	cellular lipid metabolic process	1.490004e-3
GO:0060291	long-term synaptic potentiation	1.510073e-3
GO:0010463	mesenchymal cell proliferation	1.535153e-3
GO:0008594	photoreceptor cell morphogenesis	1.547590e-3
GO:0045822	negative regulation of heart contraction	1.646242e-3
GO:0046326	positive regulation of glucose import	1.651104e-3
GO:0031114	regulation of microtubule depolymerization	1.651104e-3
GO:0042060	wound healing	1.651886e-3
GO:0034394	protein localization at cell surface	1.655174e-3
GO:0006397	mRNA processing	1.663352e-3
GO:2000319	regulation of T-helper 17 cell differentiation	1.671325e-3
GO:0018916	nitrobenzene metabolic process	1.671325e-3
GO:0030029	actin filament-based process	1.683581e-3
GO:0035303	regulation of dephosphorylation	1.707220e-3
GO:0060445	branching involved in salivary gland morphogenesis	1.760249e-3
GO:0003012	muscle system process	1.784023e-3
GO:0048878	chemical homeostasis	1.826405e-3
GO:0045404	positive regulation of interleukin-4 biosynthetic process	1.828384e-3
GO:0010828	positive regulation of glucose transport	1.868327e-3
GO:0032956	regulation of actin cytoskeleton organization	1.873211e-3
GO:0021559	trigeminal nerve development	1.897786e-3
GO:0033005	positive regulation of mast cell activation	1.900127e-3
GO:0051247	positive regulation of protein metabolic process	1.906370e-3
GO:0042108	positive regulation of cytokine biosynthetic process	1.921520e-3
GO:0048771	tissue remodeling	1.937665e-3
GO:0045762	positive regulation of adenylate cyclase activity	1.958199e-3
GO:0030832	regulation of actin filament length	1.960614e-3
GO:0006486	protein glycosylation	1.963779e-3
GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis	2.000940e-3
GO:0023061	signal release	2.008128e-3
GO:0048534	hemopoietic or lymphoid organ development	2.008558e-3
GO:0097090	presynaptic membrane organization	2.042478e-3
GO:0030833	regulation of actin filament polymerization	2.092473e-3
GO:0034340	response to type I interferon	2.097746e-3
GO:0045768	positive regulation of anti-apoptosis	2.103430e-3
GO:0051129	negative regulation of cellular component organization	2.107023e-3
GO:0051349	positive regulation of lyase activity	2.154429e-3
GO:0034314	Arp2/3 complex-mediated actin nucleation	2.155564e-3
GO:0097091	synaptic vesicle clustering	2.163755e-3
GO:0021794	thalamus development	2.163755e-3
GO:0001878	response to yeast	2.197419e-3
GO:0045722	positive regulation of gluconeogenesis	2.219563e-3
GO:0060429	epithelium development	2.242460e-3
GO:0031646	positive regulation of neurological system process	2.301182e-3
GO:0006987	activation of signaling protein activity involved in unfolded protein response	2.374880e-3
GO:0007218	neuropeptide signaling pathway	2.440182e-3
GO:0022600	digestive system process	2.468620e-3
GO:0016079	synaptic vesicle exocytosis	2.468620e-3
GO:0031532	actin cytoskeleton reorganization	2.493154e-3
GO:0050806	positive regulation of synaptic transmission	2.509845e-3
GO:0042104	positive regulation of activated T cell proliferation	2.514500e-3
GO:0002820	negative regulation of adaptive immune response	2.517033e-3
GO:0048518	positive regulation of biological process	2.527540e-3
GO:0032970	regulation of actin filament-based process	2.591794e-3
GO:0051094	positive regulation of developmental process	2.612396e-3
GO:0043984	histone H4-K16 acetylation	2.614363e-3
GO:0007224	smoothened signaling pathway	2.666232e-3
GO:0046488	phosphatidylinositol metabolic process	2.701371e-3
GO:0046006	regulation of activated T cell proliferation	2.714033e-3
GO:0045740	positive regulation of DNA replication	2.767422e-3
GO:0045597	positive regulation of cell differentiation	2.778881e-3
GO:0046070	dGTP metabolic process	2.812242e-3
GO:0006269	DNA replication, synthesis of RNA primer	2.812242e-3
GO:0006117	acetaldehyde metabolic process	2.812242e-3
GO:0032621	interleukin-18 production	2.826291e-3
GO:0009229	thiamine diphosphate biosynthetic process	2.826291e-3
GO:0009120	deoxyribonucleoside metabolic process	2.833498e-3
GO:0032922	circadian regulation of gene expression	2.838694e-3
GO:0032355	response to estradiol stimulus	2.856209e-3
GO:0045937	positive regulation of phosphate metabolic process	2.903961e-3
GO:0070358	actin polymerization-dependent cell motility	2.910181e-3
GO:0071109	superior temporal gyrus development	2.910181e-3
GO:0060396	growth hormone receptor signaling pathway	2.917435e-3
GO:0060088	auditory receptor cell stereocilium organization	2.929462e-3
GO:0031124	mRNA 3'-end processing	2.982686e-3
GO:0060117	auditory receptor cell development	3.046065e-3
GO:0046474	glycerophospholipid biosynthetic process	3.072271e-3
GO:0008585	female gonad development	3.078886e-3
GO:0006813	potassium ion transport	3.080754e-3
GO:0007156	homophilic cell adhesion	3.081452e-3
GO:0060999	positive regulation of dendritic spine development	3.124796e-3
GO:0021536	diencephalon development	3.195773e-3
GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	3.307157e-3
GO:0048666	neuron development	3.326669e-3
GO:0010389	regulation of G2/M transition of mitotic cell cycle	3.333498e-3
GO:0051290	protein heterotetramerization	3.344059e-3
GO:0002253	activation of immune response	3.385670e-3
GO:0014065	phosphatidylinositol 3-kinase cascade	3.461218e-3
GO:0015936	coenzyme A metabolic process	3.511108e-3
GO:0060122	inner ear receptor stereocilium organization	3.516436e-3
GO:0030216	keratinocyte differentiation	3.523611e-3
GO:0061039	ovum-producing ovary development	3.535496e-3
GO:0015812	gamma-aminobutyric acid transport	3.571667e-3
GO:0050869	negative regulation of B cell activation	3.595261e-3
GO:0030097	hemopoiesis	3.624598e-3
GO:0060259	regulation of feeding behavior	3.625788e-3
GO:0090285	negative regulation of protein glycosylation in Golgi	3.827163e-3
GO:0032516	positive regulation of phosphoprotein phosphatase activity	3.851732e-3
GO:0045416	positive regulation of interleukin-8 biosynthetic process	3.872968e-3
GO:0051966	regulation of synaptic transmission, glutamatergic	3.882510e-3
GO:0048486	parasympathetic nervous system development	3.883501e-3
GO:0010648	negative regulation of cell communication	3.905450e-3
GO:0006068	ethanol catabolic process	3.914007e-3
GO:0033006	regulation of mast cell activation involved in immune response	3.921626e-3
GO:0051135	positive regulation of NK T cell activation	3.993400e-3
GO:0031401	positive regulation of protein modification process	4.061788e-3
GO:0045595	regulation of cell differentiation	4.135942e-3
GO:0030595	leukocyte chemotaxis	4.139799e-3
GO:0001706	endoderm formation	4.152594e-3
GO:0046545	development of primary female sexual characteristics	4.166217e-3
GO:0071841	cellular component organization or biogenesis at cellular level	4.174043e-3
GO:0002093	auditory receptor cell morphogenesis	4.183096e-3
GO:0023057	negative regulation of signaling	4.210575e-3
GO:0042438	melanin biosynthetic process	4.211653e-3
GO:0045667	regulation of osteoblast differentiation	4.217548e-3
GO:0050808	synapse organization	4.272437e-3
GO:0045123	cellular extravasation	4.350249e-3
GO:0030335	positive regulation of cell migration	4.375157e-3
GO:0007435	salivary gland morphogenesis	4.377343e-3
GO:0072361	regulation of glycolysis by regulation of transcription from RNA polymerase II promoter	4.392513e-3
GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter	4.392513e-3
GO:0045650	negative regulation of macrophage differentiation	4.392513e-3
GO:0016553	base conversion or substitution editing	4.392513e-3
GO:0060235	lens induction in camera-type eye	4.400009e-3
GO:0002052	positive regulation of neuroblast proliferation	4.417572e-3
GO:0048641	regulation of skeletal muscle tissue development	4.421208e-3
GO:0071842	cellular component organization at cellular level	4.427345e-3
GO:0007492	endoderm development	4.466221e-3
GO:0061304	retinal blood vessel morphogenesis	4.487483e-3
GO:0045168	cell-cell signaling involved in cell fate commitment	4.501024e-3