Novel motif:89

name:	motif89_CGCCGTGTTTA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0030163	protein catabolic process	2.917675e-12
GO:0006369	termination of RNA polymerase II transcription	5.492613e-12
GO:0010498	proteasomal protein catabolic process	2.911334e-11
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	2.988052e-11
GO:0006353	transcription termination, DNA-dependent	4.443083e-11
GO:0051603	proteolysis involved in cellular protein catabolic process	6.675499e-11
GO:0044257	cellular protein catabolic process	1.201813e-10
GO:0007620	copulation	2.991707e-10
GO:0016070	RNA metabolic process	9.846117e-10
GO:0035461	vitamin transmembrane transport	1.378126e-9
GO:0034393	positive regulation of smooth muscle cell apoptosis	1.438149e-9
GO:0006511	ubiquitin-dependent protein catabolic process	2.759793e-9
GO:0019941	modification-dependent protein catabolic process	3.497639e-9
GO:0010467	gene expression	7.780495e-9
GO:0043382	positive regulation of memory T cell differentiation	8.464510e-9
GO:0043632	modification-dependent macromolecule catabolic process	9.056663e-9
GO:0090085	regulation of protein deubiquitination	9.366586e-9
GO:0006231	dTMP biosynthetic process	1.220672e-8
GO:0019088	immortalization of host cell by virus	1.220672e-8
GO:0006396	RNA processing	1.792419e-8
GO:0090086	negative regulation of protein deubiquitination	2.457225e-8
GO:0044265	cellular macromolecule catabolic process	3.232167e-8
GO:0000209	protein polyubiquitination	3.666189e-8
GO:0090304	nucleic acid metabolic process	4.671644e-8
GO:0006379	mRNA cleavage	5.623299e-8
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	6.260317e-8
GO:0001916	positive regulation of T cell mediated cytotoxicity	1.823313e-7
GO:0007618	mating	2.192872e-7
GO:0016071	mRNA metabolic process	2.225550e-7
GO:0019087	transformation of host cell by virus	2.580552e-7
GO:0035722	interleukin-12-mediated signaling pathway	3.174431e-7
GO:0009057	macromolecule catabolic process	3.581264e-7
GO:0033326	cerebrospinal fluid secretion	5.602447e-7
GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	5.864838e-7
GO:0006397	mRNA processing	6.368725e-7
GO:0042520	positive regulation of tyrosine phosphorylation of Stat4 protein	7.870449e-7
GO:0030433	ER-associated protein catabolic process	8.518091e-7
GO:0000398	nuclear mRNA splicing, via spliceosome	8.574576e-7
GO:0019048	virus-host interaction	8.830598e-7
GO:0007320	insemination	1.028559e-6
GO:0046078	dUMP metabolic process	1.098108e-6
GO:2000330	positive regulation of T-helper 17 cell lineage commitment	1.120774e-6
GO:2000318	positive regulation of T-helper 17 type immune response	1.120774e-6
GO:0044260	cellular macromolecule metabolic process	1.275557e-6
GO:0006325	chromatin organization	1.352451e-6
GO:0071934	thiamine transmembrane transport	1.410649e-6
GO:0034391	regulation of smooth muscle cell apoptosis	1.484591e-6
GO:0035357	peroxisome proliferator activated receptor signaling pathway	1.628462e-6
GO:0060574	intestinal epithelial cell maturation	1.860711e-6
GO:0051290	protein heterotetramerization	2.376018e-6
GO:0031639	plasminogen activation	2.553101e-6
GO:0006535	cysteine biosynthetic process from serine	2.658357e-6
GO:0019346	transsulfuration	2.658357e-6
GO:0043418	homocysteine catabolic process	2.658357e-6
GO:0019343	cysteine biosynthetic process via cystathionine	2.658357e-6
GO:0097045	phosphatidylserine exposure on blood platelet	3.008074e-6
GO:0000375	RNA splicing, via transesterification reactions	3.523326e-6
GO:0090141	positive regulation of mitochondrial fission	4.463922e-6
GO:0050689	negative regulation of defense response to virus by host	4.936723e-6
GO:0009798	axis specification	4.978126e-6
GO:0032915	positive regulation of transforming growth factor beta2 production	6.146701e-6
GO:0008380	RNA splicing	6.251029e-6
GO:0007494	midgut development	6.453615e-6
GO:0043484	regulation of RNA splicing	6.813002e-6
GO:0030970	retrograde protein transport, ER to cytosol	7.485501e-6
GO:0000077	DNA damage checkpoint	8.968267e-6
GO:0006351	transcription, DNA-dependent	1.072572e-5
GO:0032534	regulation of microvillus assembly	1.088895e-5
GO:0051443	positive regulation of ubiquitin-protein ligase activity	1.127327e-5
GO:0048319	axial mesoderm morphogenesis	1.140387e-5
GO:0031102	neuron projection regeneration	1.202165e-5
GO:0009163	nucleoside biosynthetic process	1.219858e-5
GO:0051865	protein autoubiquitination	1.651740e-5
GO:0016568	chromatin modification	1.883636e-5
GO:0010661	positive regulation of muscle cell apoptosis	2.008360e-5
GO:0016598	protein arginylation	2.050577e-5
GO:0019376	galactolipid catabolic process	2.229966e-5
GO:0065002	intracellular protein transmembrane transport	2.229966e-5
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	2.240387e-5
GO:0006684	sphingomyelin metabolic process	2.287663e-5
GO:0031570	DNA integrity checkpoint	2.344302e-5
GO:0071674	mononuclear cell migration	2.403061e-5
GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	2.439429e-5
GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	2.439429e-5
GO:0006139	nucleobase-containing compound metabolic process	2.613450e-5
GO:0006556	S-adenosylmethionine biosynthetic process	3.098514e-5
GO:0042977	activation of JAK2 kinase activity	3.244135e-5
GO:0045090	retroviral genome replication	3.438709e-5
GO:0046985	positive regulation of hemoglobin biosynthetic process	3.438709e-5
GO:0043973	histone H3-K4 acetylation	3.438709e-5
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	3.438709e-5
GO:0030185	nitric oxide transport	3.763925e-5
GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint	3.827180e-5
GO:0032774	RNA biosynthetic process	4.492829e-5
GO:0090140	regulation of mitochondrial fission	4.578783e-5
GO:0019448	L-cysteine catabolic process	4.627296e-5
GO:0009162	deoxyribonucleoside monophosphate metabolic process	4.784029e-5
GO:0006335	DNA replication-dependent nucleosome assembly	4.784029e-5
GO:0002069	columnar/cuboidal epithelial cell maturation	5.943350e-5
GO:0006406	mRNA export from nucleus	6.249775e-5
GO:0031124	mRNA 3'-end processing	6.529377e-5
GO:0010224	response to UV-B	7.068311e-5
GO:0010506	regulation of autophagy	7.198184e-5
GO:0046683	response to organophosphorus	7.258925e-5
GO:0006400	tRNA modification	7.814091e-5
GO:0042503	tyrosine phosphorylation of Stat3 protein	8.027722e-5
GO:0000387	spliceosomal snRNP assembly	8.149822e-5
GO:0010821	regulation of mitochondrion organization	8.257060e-5
GO:0034644	cellular response to UV	8.465138e-5
GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway	8.651199e-5
GO:0060248	detection of cell density by contact stimulus involved in contact inhibition	8.651199e-5
GO:0072285	mesenchymal to epithelial transition involved in metanephric renal vesicle formation	8.651199e-5
GO:0006427	histidyl-tRNA aminoacylation	8.651199e-5
GO:0045358	negative regulation of interferon-beta biosynthetic process	8.651199e-5
GO:0007371	ventral midline determination	8.651199e-5
GO:0051932	synaptic transmission, GABAergic	8.951793e-5
GO:0000073	spindle pole body separation	8.951793e-5
GO:0008616	queuosine biosynthetic process	8.951793e-5
GO:0019374	galactolipid metabolic process	9.193575e-5
GO:0048102	autophagic cell death	9.296942e-5
GO:0060658	nipple morphogenesis	9.296942e-5
GO:0071779	G1/S transition checkpoint	9.348068e-5
GO:0071482	cellular response to light stimulus	9.823322e-5
GO:0051351	positive regulation of ligase activity	1.028060e-4
GO:0045626	negative regulation of T-helper 1 cell differentiation	1.062153e-4
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.094985e-4
GO:0070842	aggresome assembly	1.100684e-4
GO:0009399	nitrogen fixation	1.202385e-4
GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	1.232023e-4
GO:0032530	regulation of microvillus organization	1.298280e-4
GO:0072404	signal transduction involved in G1/S transition checkpoint	1.318132e-4
GO:0042770	signal transduction in response to DNA damage	1.433141e-4
GO:0048318	axial mesoderm development	1.503090e-4
GO:0031123	RNA 3'-end processing	1.516388e-4
GO:0031575	mitotic cell cycle G1/S transition checkpoint	1.553433e-4
GO:0044332	Wnt receptor signaling pathway involved in dorsal/ventral axis specification	1.562475e-4
GO:0006333	chromatin assembly or disassembly	1.645833e-4
GO:0072395	signal transduction involved in cell cycle checkpoint	1.763131e-4
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.776218e-4
GO:0070814	hydrogen sulfide biosynthetic process	1.785170e-4
GO:0070079	histone H4-R3 demethylation	1.845981e-4
GO:0070078	histone H3-R2 demethylation	1.845981e-4
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	1.845981e-4
GO:0035279	mRNA cleavage involved in gene silencing by miRNA	1.880287e-4
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.896465e-4
GO:0043249	erythrocyte maturation	1.899344e-4
GO:0045736	negative regulation of cyclin-dependent protein kinase activity	1.919151e-4
GO:0070671	response to interleukin-12	1.964962e-4
GO:2000045	regulation of G1/S transition of mitotic cell cycle	2.019412e-4
GO:0007031	peroxisome organization	2.041505e-4
GO:0034063	stress granule assembly	2.082529e-4
GO:0007339	binding of sperm to zona pellucida	2.189715e-4
GO:0055107	Golgi to secretory granule transport	2.274686e-4
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	2.318327e-4
GO:0015887	pantothenate transmembrane transport	2.329301e-4
GO:0015878	biotin transport	2.329301e-4
GO:0070986	left/right axis specification	2.427837e-4
GO:0018872	arsonoacetate metabolic process	2.459977e-4
GO:0031103	axon regeneration	2.496405e-4
GO:0032700	negative regulation of interleukin-17 production	2.646527e-4
GO:0046128	purine ribonucleoside metabolic process	2.738417e-4
GO:0035329	hippo signaling cascade	2.756941e-4
GO:0090083	regulation of inclusion body assembly	2.800277e-4
GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	2.902848e-4
GO:0031638	zymogen activation	2.925238e-4
GO:0010455	positive regulation of cell fate commitment	2.925238e-4
GO:0006268	DNA unwinding involved in replication	2.925238e-4
GO:0072422	signal transduction involved in DNA damage checkpoint	3.076841e-4
GO:0006481	C-terminal protein methylation	3.157027e-4
GO:0044237	cellular metabolic process	3.179329e-4
GO:0010507	negative regulation of autophagy	3.345109e-4
GO:0050652	dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	3.520559e-4
GO:0090138	regulation of actin cytoskeleton organization by cell-cell adhesion	3.520559e-4
GO:0035409	histone H3-Y41 phosphorylation	3.616114e-4
GO:0008636	activation of caspase activity by protein phosphorylation	3.616114e-4
GO:0035771	interleukin-4-mediated signaling pathway	3.682396e-4
GO:0050691	regulation of defense response to virus by host	3.935261e-4
GO:0060286	flagellar cell motility	3.945061e-4
GO:0001555	oocyte growth	3.945061e-4
GO:0043471	regulation of cellular carbohydrate catabolic process	4.030640e-4
GO:0048280	vesicle fusion with Golgi apparatus	4.047235e-4
GO:0071415	cellular response to purine-containing compound	4.110780e-4
GO:0051383	kinetochore organization	4.125364e-4
GO:0000075	cell cycle checkpoint	4.151692e-4
GO:0051438	regulation of ubiquitin-protein ligase activity	4.188790e-4
GO:0010824	regulation of centrosome duplication	4.239213e-4
GO:0090084	negative regulation of inclusion body assembly	4.311388e-4
GO:0021587	cerebellum morphogenesis	4.498727e-4
GO:0034641	cellular nitrogen compound metabolic process	4.537576e-4
GO:0070647	protein modification by small protein conjugation or removal	4.597454e-4
GO:0006281	DNA repair	4.822696e-4
GO:0015671	oxygen transport	4.872318e-4
GO:0009956	radial pattern formation	4.941545e-4
GO:0061084	negative regulation of protein refolding	4.941545e-4
GO:0009992	cellular water homeostasis	5.039700e-4
GO:0016567	protein ubiquitination	5.123176e-4
GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway	5.285851e-4
GO:0006807	nitrogen compound metabolic process	5.408140e-4
GO:0046796	viral genome transport in host cell	5.434777e-4
GO:0046314	phosphocreatine biosynthetic process	5.435998e-4
GO:0010734	negative regulation of protein glutathionylation	5.441229e-4
GO:0050687	negative regulation of defense response to virus	5.648335e-4
GO:0060981	cell migration involved in coronary angiogenesis	6.398399e-4
GO:0071670	smooth muscle cell chemotaxis	6.398399e-4
GO:0060823	canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation	6.398399e-4
GO:0001575	globoside metabolic process	6.398399e-4
GO:0035752	lysosomal lumen pH elevation	6.398399e-4
GO:0000046	autophagic vacuole fusion	6.398399e-4
GO:0006413	translational initiation	6.539170e-4
GO:0006119	oxidative phosphorylation	6.622669e-4
GO:0009051	pentose-phosphate shunt, oxidative branch	6.718403e-4
GO:0042278	purine nucleoside metabolic process	7.139472e-4
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	7.151121e-4
GO:0000278	mitotic cell cycle	7.306630e-4
GO:0051148	negative regulation of muscle cell differentiation	7.328796e-4
GO:0043380	regulation of memory T cell differentiation	7.485864e-4
GO:0010624	regulation of Schwann cell proliferation	7.525882e-4
GO:0021797	forebrain anterior/posterior pattern specification	7.578937e-4
GO:0060687	regulation of branching involved in prostate gland morphogenesis	7.864416e-4
GO:0010822	positive regulation of mitochondrion organization	7.899378e-4
GO:0042976	activation of Janus kinase activity	8.051360e-4
GO:0090197	positive regulation of chemokine secretion	8.185544e-4
GO:0060836	lymphatic endothelial cell differentiation	8.237307e-4
GO:0060419	heart growth	8.295112e-4
GO:0032479	regulation of type I interferon production	8.351309e-4
GO:2000573	positive regulation of DNA biosynthetic process	8.862030e-4
GO:0070936	protein K48-linked ubiquitination	8.898741e-4
GO:0035036	sperm-egg recognition	8.913654e-4
GO:0033630	positive regulation of cell adhesion mediated by integrin	9.124198e-4
GO:0045653	negative regulation of megakaryocyte differentiation	9.399324e-4
GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	9.837911e-4
GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	9.837911e-4
GO:0034401	regulation of transcription by chromatin organization	1.005955e-3
GO:0034728	nucleosome organization	1.025777e-3
GO:0009436	glyoxylate catabolic process	1.031745e-3
GO:0043308	eosinophil degranulation	1.062559e-3
GO:0009234	menaquinone biosynthetic process	1.062559e-3
GO:0030827	negative regulation of cGMP biosynthetic process	1.062559e-3
GO:0034695	response to prostaglandin E stimulus	1.069767e-3
GO:0051568	histone H3-K4 methylation	1.079552e-3
GO:0046984	regulation of hemoglobin biosynthetic process	1.106714e-3
GO:0046129	purine ribonucleoside biosynthetic process	1.106777e-3
GO:0051329	interphase of mitotic cell cycle	1.157727e-3
GO:0043392	negative regulation of DNA binding	1.188583e-3
GO:0007498	mesoderm development	1.199193e-3
GO:0070417	cellular response to cold	1.232850e-3
GO:0042396	phosphagen biosynthetic process	1.239788e-3
GO:0032275	luteinizing hormone secretion	1.297149e-3
GO:0046884	follicle-stimulating hormone secretion	1.297149e-3
GO:0032785	negative regulation of transcription elongation, DNA-dependent	1.309938e-3
GO:0002711	positive regulation of T cell mediated immunity	1.318723e-3
GO:0051301	cell division	1.330112e-3
GO:0046605	regulation of centrosome cycle	1.342621e-3
GO:0042373	vitamin K metabolic process	1.343216e-3
GO:0009411	response to UV	1.407301e-3
GO:0051028	mRNA transport	1.423881e-3
GO:0016242	negative regulation of macroautophagy	1.448142e-3
GO:0070060	'de novo' actin filament nucleation	1.448142e-3
GO:0032648	regulation of interferon-beta production	1.483431e-3
GO:0031497	chromatin assembly	1.513584e-3
GO:0048024	regulation of nuclear mRNA splicing, via spliceosome	1.562175e-3
GO:0060242	contact inhibition	1.601298e-3
GO:0034723	DNA replication-dependent nucleosome organization	1.601298e-3
GO:0046500	S-adenosylmethionine metabolic process	1.607765e-3
GO:0050684	regulation of mRNA processing	1.608205e-3
GO:0043984	histone H4-K16 acetylation	1.614718e-3
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.635458e-3
GO:0001840	neural plate development	1.635971e-3
GO:0006334	nucleosome assembly	1.662678e-3
GO:0071824	protein-DNA complex subunit organization	1.670189e-3
GO:0031023	microtubule organizing center organization	1.703270e-3
GO:0001920	negative regulation of receptor recycling	1.760950e-3
GO:0060972	left/right pattern formation	1.775176e-3
GO:0071233	cellular response to leucine	1.775238e-3
GO:0042772	DNA damage response, signal transduction resulting in transcription	1.786713e-3
GO:0016570	histone modification	1.798571e-3
GO:0007009	plasma membrane organization	1.810806e-3
GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis	1.824842e-3
GO:0033632	regulation of cell-cell adhesion mediated by integrin	1.836859e-3
GO:0051340	regulation of ligase activity	1.841877e-3
GO:0090196	regulation of chemokine secretion	1.843549e-3
GO:0009116	nucleoside metabolic process	1.866844e-3
GO:0060648	mammary gland bud morphogenesis	1.878739e-3
GO:0032446	protein modification by small protein conjugation	1.906286e-3
GO:0033148	positive regulation of estrogen receptor signaling pathway	1.936720e-3
GO:0010626	negative regulation of Schwann cell proliferation	1.950886e-3
GO:0051325	interphase	1.982992e-3
GO:0006403	RNA localization	2.030992e-3
GO:0051276	chromosome organization	2.041796e-3
GO:0060038	cardiac muscle cell proliferation	2.048121e-3
GO:0071954	chemokine (C-C motif) ligand 11 production	2.055747e-3
GO:2000525	positive regulation of T cell costimulation	2.055747e-3
GO:0002215	defense response to nematode	2.055747e-3
GO:0035712	T-helper 2 cell activation	2.055747e-3
GO:0035709	memory T cell activation	2.055747e-3
GO:0035708	interleukin-4-dependent isotype switching to IgE isotypes	2.055747e-3
GO:0009950	dorsal/ventral axis specification	2.056779e-3
GO:0060973	cell migration involved in heart development	2.078230e-3
GO:0070103	regulation of interleukin-6-mediated signaling pathway	2.093092e-3
GO:0046134	pyrimidine nucleoside biosynthetic process	2.129784e-3
GO:0072348	sulfur compound transport	2.146722e-3
GO:0001914	regulation of T cell mediated cytotoxicity	2.176565e-3
GO:0034645	cellular macromolecule biosynthetic process	2.181547e-3
GO:0006405	RNA export from nucleus	2.190764e-3
GO:0060399	positive regulation of growth hormone receptor signaling pathway	2.209289e-3
GO:0046108	uridine metabolic process	2.209289e-3
GO:0033634	positive regulation of cell-cell adhesion mediated by integrin	2.236040e-3
GO:0042398	cellular modified amino acid biosynthetic process	2.260858e-3
GO:0002067	glandular epithelial cell differentiation	2.281237e-3
GO:0015910	peroxisomal long-chain fatty acid import	2.315172e-3
GO:0016569	covalent chromatin modification	2.348495e-3
GO:0022618	ribonucleoprotein complex assembly	2.371052e-3
GO:0048320	axial mesoderm formation	2.382307e-3
GO:0060921	sinoatrial node cell differentiation	2.526629e-3
GO:0060975	cardioblast migration to the midline involved in heart field formation	2.526629e-3
GO:0042664	negative regulation of endodermal cell fate specification	2.526629e-3
GO:0071799	cellular response to prostaglandin D stimulus	2.526629e-3
GO:0003236	sinus venosus morphogenesis	2.526629e-3
GO:0003210	cardiac atrium formation	2.526629e-3
GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	2.526629e-3
GO:0003241	growth involved in heart morphogenesis	2.526629e-3
GO:0003259	cardioblast anterior-lateral migration	2.526629e-3
GO:0051444	negative regulation of ubiquitin-protein ligase activity	2.537170e-3
GO:0035881	amacrine cell differentiation	2.621034e-3
GO:0019344	cysteine biosynthetic process	2.766599e-3
GO:0051252	regulation of RNA metabolic process	2.814916e-3
GO:0051454	intracellular pH elevation	2.830152e-3
GO:0042771	DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis	2.884129e-3
GO:2000249	regulation of actin cytoskeleton reorganization	2.897319e-3
GO:0051135	positive regulation of NK T cell activation	2.900701e-3
GO:0006098	pentose-phosphate shunt	2.974870e-3
GO:0034048	negative regulation of protein phosphatase type 2A activity	2.985678e-3
GO:0060649	mammary gland bud elongation	3.056451e-3
GO:0060659	nipple sheath formation	3.056451e-3
GO:0034660	ncRNA metabolic process	3.237417e-3
GO:0030330	DNA damage response, signal transduction by p53 class mediator	3.266330e-3
GO:0006683	galactosylceramide catabolic process	3.283801e-3
GO:0035372	protein localization to microtubule	3.283801e-3
GO:0002051	osteoblast fate commitment	3.318422e-3
GO:0032329	serine transport	3.331759e-3
GO:0042088	T-helper 1 type immune response	3.335155e-3
GO:0042832	defense response to protozoan	3.344409e-3
GO:0018205	peptidyl-lysine modification	3.366975e-3
GO:0034968	histone lysine methylation	3.412159e-3
GO:0071156	regulation of cell cycle arrest	3.416084e-3
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	3.434392e-3
GO:0009303	rRNA transcription	3.460951e-3
GO:0060124	positive regulation of growth hormone secretion	3.490147e-3
GO:0046599	regulation of centriole replication	3.597092e-3
GO:0003002	regionalization	3.660291e-3
GO:0006189	'de novo' IMP biosynthetic process	3.763033e-3
GO:0042775	mitochondrial ATP synthesis coupled electron transport	3.774907e-3
GO:0010610	regulation of mRNA stability involved in response to stress	3.795213e-3
GO:0009231	riboflavin biosynthetic process	3.795213e-3
GO:0006974	response to DNA damage stimulus	3.818179e-3
GO:0006386	termination of RNA polymerase III transcription	3.826805e-3
GO:0006385	transcription elongation from RNA polymerase III promoter	3.826805e-3
GO:0051583	dopamine uptake	3.872953e-3
GO:0070105	positive regulation of interleukin-6-mediated signaling pathway	4.011040e-3
GO:0034243	regulation of transcription elongation from RNA polymerase II promoter	4.027110e-3
GO:0000079	regulation of cyclin-dependent protein kinase activity	4.037674e-3
GO:0019693	ribose phosphate metabolic process	4.062799e-3
GO:0006463	steroid hormone receptor complex assembly	4.096976e-3
GO:0090007	regulation of mitotic anaphase	4.148279e-3
GO:0051488	activation of anaphase-promoting complex activity	4.155385e-3
GO:0042506	tyrosine phosphorylation of Stat5 protein	4.155385e-3
GO:0016573	histone acetylation	4.174229e-3
GO:0033628	regulation of cell adhesion mediated by integrin	4.183277e-3
GO:0010660	regulation of muscle cell apoptosis	4.233965e-3
GO:0031398	positive regulation of protein ubiquitination	4.292881e-3
GO:0033145	positive regulation of steroid hormone receptor signaling pathway	4.308098e-3
GO:0001839	neural plate morphogenesis	4.381822e-3
GO:0040015	negative regulation of multicellular organism growth	4.387886e-3
GO:0009059	macromolecule biosynthetic process	4.501488e-3
GO:0035196	production of miRNAs involved in gene silencing by miRNA	4.538273e-3
GO:0002230	positive regulation of defense response to virus by host	4.642215e-3
GO:0006825	copper ion transport	4.642864e-3
GO:0006681	galactosylceramide metabolic process	4.680322e-3
GO:0010715	regulation of extracellular matrix disassembly	4.693033e-3
GO:0000422	mitochondrion degradation	4.711431e-3
GO:0009119	ribonucleoside metabolic process	4.883497e-3
GO:0070358	actin polymerization-dependent cell motility	4.974740e-3
GO:0060058	positive regulation of apoptosis involved in mammary gland involution	4.978485e-3
GO:0035089	establishment of apical/basal cell polarity	5.159540e-3
GO:0090399	replicative senescence	5.167855e-3
GO:0001562	response to protozoan	5.181786e-3
GO:0048384	retinoic acid receptor signaling pathway	5.234736e-3
GO:0007093	mitotic cell cycle checkpoint	5.263710e-3
GO:0000956	nuclear-transcribed mRNA catabolic process	5.302790e-3
GO:0051169	nuclear transport	5.307243e-3
GO:0060235	lens induction in camera-type eye	5.356107e-3
GO:0051154	negative regulation of striated muscle cell differentiation	5.393819e-3
GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process	5.395125e-3
GO:0090344	negative regulation of cell aging	5.422267e-3
GO:0033146	regulation of estrogen receptor signaling pathway	5.448419e-3
GO:0032816	positive regulation of natural killer cell activation	5.448419e-3
GO:0055017	cardiac muscle tissue growth	5.499484e-3
GO:0071353	cellular response to interleukin-4	5.648301e-3
GO:0017121	phospholipid scrambling	5.677251e-3
GO:0014060	regulation of epinephrine secretion	5.688781e-3
GO:0003219	cardiac right ventricle formation	5.688781e-3
GO:0071826	ribonucleoprotein complex subunit organization	5.738011e-3
GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process	5.902499e-3
GO:0000088	mitotic prophase	5.902499e-3
GO:0035195	gene silencing by miRNA	5.952832e-3
GO:0032876	negative regulation of DNA endoreduplication	6.083662e-3
GO:0006110	regulation of glycolysis	6.102687e-3
GO:0006913	nucleocytoplasmic transport	6.104982e-3
GO:0046952	ketone body catabolic process	6.136440e-3
GO:0044273	sulfur compound catabolic process	6.153033e-3
GO:0042363	fat-soluble vitamin catabolic process	6.180540e-3
GO:0046950	cellular ketone body metabolic process	6.203828e-3
GO:0006868	glutamine transport	6.203828e-3
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	6.230215e-3
GO:0007509	mesoderm migration involved in gastrulation	6.235582e-3
GO:0006298	mismatch repair	6.359135e-3
GO:0042727	flavin-containing compound biosynthetic process	6.392163e-3
GO:0001830	trophectodermal cell fate commitment	6.392163e-3
GO:0034314	Arp2/3 complex-mediated actin nucleation	6.392163e-3
GO:0045793	positive regulation of cell size	6.493870e-3
GO:0065004	protein-DNA complex assembly	6.516658e-3
GO:0040040	thermosensory behavior	6.661182e-3
GO:0051168	nuclear export	6.665112e-3
GO:0006206	pyrimidine base metabolic process	6.673129e-3
GO:0051182	coenzyme transport	6.750930e-3
GO:0000080	G1 phase of mitotic cell cycle	6.860748e-3
GO:0016571	histone methylation	6.898084e-3
GO:0032811	negative regulation of epinephrine secretion	6.899179e-3
GO:0035265	organ growth	6.961623e-3
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	6.977311e-3
GO:0006565	L-serine catabolic process	6.990212e-3
GO:0000715	nucleotide-excision repair, DNA damage recognition	7.078392e-3
GO:0009948	anterior/posterior axis specification	7.104494e-3
GO:0042723	thiamine-containing compound metabolic process	7.482825e-3
GO:0018065	protein-cofactor linkage	7.508391e-3
GO:0006355	regulation of transcription, DNA-dependent	7.517115e-3
GO:0051297	centrosome organization	7.584535e-3
GO:0018394	peptidyl-lysine acetylation	7.588391e-3
GO:0042093	T-helper cell differentiation	7.623723e-3
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	7.629009e-3
GO:0007253	cytoplasmic sequestering of NF-kappaB	7.692825e-3
GO:0048368	lateral mesoderm development	7.703619e-3
GO:0006740	NADPH regeneration	7.800377e-3
GO:0060849	regulation of transcription involved in lymphatic endothelial cell fate commitment	7.862849e-3
GO:0046951	ketone body biosynthetic process	7.911793e-3
GO:0042637	catagen	7.911793e-3
GO:0032383	regulation of intracellular cholesterol transport	7.916157e-3
GO:0070918	production of small RNA involved in gene silencing by RNA	7.923203e-3
GO:0042418	epinephrine biosynthetic process	8.004614e-3
GO:0035280	miRNA loading onto RISC involved in gene silencing by miRNA	8.004614e-3
GO:0021933	radial glia guided migration of cerebellar granule cell	8.004614e-3
GO:0006585	dopamine biosynthetic process from tyrosine	8.004614e-3
GO:0043170	macromolecule metabolic process	8.025472e-3
GO:0060427	lung connective tissue development	8.070229e-3
GO:0032070	regulation of deoxyribonuclease activity	8.070229e-3
GO:0015680	intracellular copper ion transport	8.070229e-3
GO:0032474	otolith morphogenesis	8.088591e-3
GO:0031119	tRNA pseudouridine synthesis	8.088591e-3
GO:0060398	regulation of growth hormone receptor signaling pathway	8.125354e-3
GO:0043585	nose morphogenesis	8.176199e-3
GO:0030823	regulation of cGMP metabolic process	8.217229e-3
GO:0060206	estrous cycle phase	8.217229e-3
GO:0060711	labyrinthine layer development	8.236531e-3
GO:0051382	kinetochore assembly	8.339304e-3
GO:0010700	negative regulation of norepinephrine secretion	8.395093e-3
GO:0043060	meiotic metaphase I plate congression	8.417001e-3
GO:0018393	internal peptidyl-lysine acetylation	8.469168e-3
GO:0002839	positive regulation of immune response to tumor cell	8.564835e-3
GO:0015669	gas transport	8.702777e-3
GO:0003407	neural retina development	8.830143e-3
GO:0010225	response to UV-C	8.874069e-3
GO:0034616	response to laminar fluid shear stress	8.972158e-3
GO:0045746	negative regulation of Notch signaling pathway	9.033177e-3
GO:0048593	camera-type eye morphogenesis	9.174008e-3
GO:0009637	response to blue light	9.223054e-3
GO:0021526	medial motor column neuron differentiation	9.284158e-3
GO:0008617	guanosine metabolic process	9.291346e-3
GO:0022900	electron transport chain	9.441861e-3
GO:0072331	signal transduction by p53 class mediator	9.632495e-3
GO:0090199	regulation of release of cytochrome c from mitochondria	9.680511e-3
GO:0018126	protein hydroxylation	9.713872e-3
GO:0043574	peroxisomal transport	9.926866e-3
GO:0003105	negative regulation of glomerular filtration	1.003072e-2
GO:2000104	negative regulation of DNA-dependent DNA replication	1.005189e-2
GO:0000244	assembly of spliceosomal tri-snRNP	1.007964e-2
GO:0032660	regulation of interleukin-17 production	1.010142e-2
GO:0070389	chaperone cofactor-dependent protein refolding	1.018234e-2
GO:0048554	positive regulation of metalloenzyme activity	1.030734e-2
GO:0045819	positive regulation of glycogen catabolic process	1.056164e-2
GO:0032594	protein transport within lipid bilayer	1.056282e-2
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	1.058932e-2
GO:0043543	protein acylation	1.072990e-2
GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis	1.074477e-2
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	1.074477e-2
GO:0061302	smooth muscle cell-matrix adhesion	1.074477e-2
GO:0033483	gas homeostasis	1.087875e-2
GO:0090201	negative regulation of release of cytochrome c from mitochondria	1.098399e-2
GO:0000082	G1/S transition of mitotic cell cycle	1.127590e-2
GO:0060576	intestinal epithelial cell development	1.133267e-2
GO:0010002	cardioblast differentiation	1.144196e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0090304	nucleic acid metabolic process	5.126838e-11
GO:0045653	negative regulation of megakaryocyte differentiation	5.198810e-11
GO:0010467	gene expression	3.231668e-10
GO:0048743	positive regulation of skeletal muscle fiber development	6.859343e-10
GO:0043001	Golgi to plasma membrane protein transport	3.734501e-9
GO:0015966	diadenosine tetraphosphate biosynthetic process	4.857078e-9
GO:0016070	RNA metabolic process	1.253623e-8
GO:0051028	mRNA transport	1.279973e-8
GO:0006139	nucleobase-containing compound metabolic process	2.052973e-8
GO:0006893	Golgi to plasma membrane transport	5.665356e-8
GO:0008612	peptidyl-lysine modification to hypusine	9.152360e-8
GO:0034227	tRNA thio-modification	1.017094e-7
GO:0044260	cellular macromolecule metabolic process	1.652809e-7
GO:0034337	RNA folding	1.857218e-7
GO:0006403	RNA localization	2.686574e-7
GO:0044029	hypomethylation of CpG island	5.387475e-7
GO:0002098	tRNA wobble uridine modification	7.912505e-7
GO:0034641	cellular nitrogen compound metabolic process	9.749608e-7
GO:0033617	mitochondrial respiratory chain complex IV assembly	1.153363e-6
GO:0048239	negative regulation of DNA recombination at telomere	1.153363e-6
GO:0006430	lysyl-tRNA aminoacylation	1.153363e-6
GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	1.269130e-6
GO:0006892	post-Golgi vesicle-mediated transport	1.366587e-6
GO:0006651	diacylglycerol biosynthetic process	1.598232e-6
GO:0010631	epithelial cell migration	1.767288e-6
GO:0006306	DNA methylation	2.258096e-6
GO:0048193	Golgi vesicle transport	2.258626e-6
GO:2000279	negative regulation of DNA biosynthetic process	2.642127e-6
GO:0045905	positive regulation of translational termination	2.674782e-6
GO:0006452	translational frameshifting	2.674782e-6
GO:0045901	positive regulation of translational elongation	2.674782e-6
GO:0070078	histone H3-R2 demethylation	2.873655e-6
GO:0070079	histone H4-R3 demethylation	2.873655e-6
GO:0022417	protein maturation by protein folding	2.873655e-6
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	2.873655e-6
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	2.873655e-6
GO:0033591	response to L-ascorbic acid	3.063399e-6
GO:0045746	negative regulation of Notch signaling pathway	3.201229e-6
GO:0050658	RNA transport	3.266777e-6
GO:0010288	response to lead ion	5.574610e-6
GO:0001892	embryonic placenta development	6.513981e-6
GO:0006449	regulation of translational termination	8.420187e-6
GO:0034101	erythrocyte homeostasis	8.871155e-6
GO:0006807	nitrogen compound metabolic process	9.171446e-6
GO:2000278	regulation of DNA biosynthetic process	9.299690e-6
GO:0045652	regulation of megakaryocyte differentiation	1.223368e-5
GO:0044030	regulation of DNA methylation	1.288600e-5
GO:0048643	positive regulation of skeletal muscle tissue development	1.327712e-5
GO:0034728	nucleosome organization	1.570337e-5
GO:0006396	RNA processing	1.703314e-5
GO:0045585	positive regulation of cytotoxic T cell differentiation	1.961401e-5
GO:0032693	negative regulation of interleukin-10 production	1.998869e-5
GO:0016071	mRNA metabolic process	2.363188e-5
GO:0006397	mRNA processing	2.497744e-5
GO:0006334	nucleosome assembly	2.926139e-5
GO:0090130	tissue migration	3.115190e-5
GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway	3.201980e-5
GO:0019348	dolichol metabolic process	3.265081e-5
GO:0001832	blastocyst growth	3.273569e-5
GO:0015959	diadenosine polyphosphate metabolic process	3.290532e-5
GO:0030218	erythrocyte differentiation	3.471562e-5
GO:0002678	positive regulation of chronic inflammatory response	3.487782e-5
GO:0006448	regulation of translational elongation	3.944523e-5
GO:0000079	regulation of cyclin-dependent protein kinase activity	4.282613e-5
GO:0051131	chaperone-mediated protein complex assembly	4.378154e-5
GO:0006402	mRNA catabolic process	4.695266e-5
GO:0040019	positive regulation of embryonic development	4.708490e-5
GO:0018192	enzyme active site formation via L-cysteine persulfide	4.911621e-5
GO:0072355	histone H3-T3 phosphorylation	5.468101e-5
GO:0042703	menstruation	5.468101e-5
GO:0019101	female somatic sex determination	5.468101e-5
GO:0006259	DNA metabolic process	5.672984e-5
GO:0065004	protein-DNA complex assembly	5.918210e-5
GO:0000956	nuclear-transcribed mRNA catabolic process	6.474364e-5
GO:0046339	diacylglycerol metabolic process	6.506837e-5
GO:0016578	histone deubiquitination	6.689603e-5
GO:0009296	flagellum assembly	6.689603e-5
GO:0071103	DNA conformation change	6.974566e-5
GO:0006351	transcription, DNA-dependent	8.231168e-5
GO:0090138	regulation of actin cytoskeleton organization by cell-cell adhesion	8.423515e-5
GO:0051901	positive regulation of mitochondrial depolarization	8.618252e-5
GO:0032774	RNA biosynthetic process	9.750826e-5
GO:0009956	radial pattern formation	9.949842e-5
GO:0032205	negative regulation of telomere maintenance	1.105140e-4
GO:0045844	positive regulation of striated muscle tissue development	1.106350e-4
GO:0032274	gonadotropin secretion	1.111073e-4
GO:0051661	maintenance of centrosome location	1.164113e-4
GO:0090086	negative regulation of protein deubiquitination	1.218419e-4
GO:0006323	DNA packaging	1.338314e-4
GO:0008593	regulation of Notch signaling pathway	1.387233e-4
GO:0006507	GPI anchor release	1.425016e-4
GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process	1.425016e-4
GO:0006304	DNA modification	1.567227e-4
GO:0043064	flagellum organization	1.836844e-4
GO:0060711	labyrinthine layer development	2.126103e-4
GO:0048024	regulation of nuclear mRNA splicing, via spliceosome	2.215461e-4
GO:0034276	kynurenic acid biosynthetic process	2.396136e-4
GO:0019046	reactivation of latent virus	2.396136e-4
GO:0002534	cytokine production involved in inflammatory response	2.396136e-4
GO:0000027	ribosomal large subunit assembly	2.396136e-4
GO:0042218	1-aminocyclopropane-1-carboxylate biosynthetic process	2.413211e-4
GO:0001913	T cell mediated cytotoxicity	2.505333e-4
GO:0071824	protein-DNA complex subunit organization	2.540401e-4
GO:0072498	embryonic skeletal joint development	2.727783e-4
GO:0043048	dolichyl monophosphate biosynthetic process	2.737419e-4
GO:0072334	UDP-galactose transmembrane transport	2.737419e-4
GO:0000244	assembly of spliceosomal tri-snRNP	2.737419e-4
GO:0031497	chromatin assembly	3.051971e-4
GO:0006626	protein targeting to mitochondrion	3.091032e-4
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	3.111116e-4
GO:0051155	positive regulation of striated muscle cell differentiation	3.112731e-4
GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	3.162935e-4
GO:0043484	regulation of RNA splicing	3.182391e-4
GO:0035137	hindlimb morphogenesis	3.343712e-4
GO:0046929	negative regulation of neurotransmitter secretion	3.468844e-4
GO:0003050	regulation of systemic arterial blood pressure by atrial natriuretic peptide	3.468844e-4
GO:0007288	sperm axoneme assembly	3.615072e-4
GO:0046626	regulation of insulin receptor signaling pathway	3.638489e-4
GO:0034645	cellular macromolecule biosynthetic process	3.649841e-4
GO:0016068	type I hypersensitivity	3.822474e-4
GO:0031057	negative regulation of histone modification	4.339762e-4
GO:0003310	pancreatic A cell differentiation	4.480112e-4
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	4.707702e-4
GO:0006888	ER to Golgi vesicle-mediated transport	4.870913e-4
GO:0000415	negative regulation of histone H3-K36 methylation	4.956382e-4
GO:0035269	protein O-linked mannosylation	4.956382e-4
GO:0031576	G2/M transition checkpoint	5.031056e-4
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	5.050660e-4
GO:0042694	muscle cell fate specification	5.050660e-4
GO:0032515	negative regulation of phosphoprotein phosphatase activity	5.131882e-4
GO:0060024	rhythmic synaptic transmission	5.131882e-4
GO:0090212	negative regulation of establishment of blood-brain barrier	5.302002e-4
GO:0015969	guanosine tetraphosphate metabolic process	5.302002e-4
GO:0002638	negative regulation of immunoglobulin production	5.302002e-4
GO:0001811	negative regulation of type I hypersensitivity	5.302002e-4
GO:0009059	macromolecule biosynthetic process	5.454806e-4
GO:0060272	embryonic skeletal joint morphogenesis	5.902485e-4
GO:0006401	RNA catabolic process	5.904242e-4
GO:0030101	natural killer cell activation	5.985654e-4
GO:0000722	telomere maintenance via recombination	6.201983e-4
GO:0043170	macromolecule metabolic process	6.267330e-4
GO:0008380	RNA splicing	6.441836e-4
GO:0006368	transcription elongation from RNA polymerase II promoter	6.616956e-4
GO:0006325	chromatin organization	6.655615e-4
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	6.851489e-4
GO:0090288	negative regulation of cellular response to growth factor stimulus	7.488748e-4
GO:0060710	chorio-allantoic fusion	7.585860e-4
GO:0060849	regulation of transcription involved in lymphatic endothelial cell fate commitment	7.846131e-4
GO:0051276	chromosome organization	8.179736e-4
GO:0030719	P granule organization	8.229217e-4
GO:0002763	positive regulation of myeloid leukocyte differentiation	8.726414e-4
GO:0034551	mitochondrial respiratory chain complex III assembly	9.539594e-4
GO:0018993	somatic sex determination	9.539594e-4
GO:0050886	endocrine process	9.958939e-4
GO:0070086	ubiquitin-dependent endocytosis	1.005719e-3
GO:0019858	cytosine metabolic process	1.005719e-3
GO:0097151	positive regulation of inhibitory postsynaptic membrane potential	1.005719e-3
GO:0001966	thigmotaxis	1.005719e-3
GO:0007630	jump response	1.005719e-3
GO:0009637	response to blue light	1.005719e-3
GO:0034619	cellular chaperone-mediated protein complex assembly	1.006141e-3
GO:0021750	vestibular nucleus development	1.006141e-3
GO:0021590	cerebellum maturation	1.006141e-3
GO:0021679	cerebellar molecular layer development	1.006141e-3
GO:0060839	endothelial cell fate commitment	1.020159e-3
GO:0035082	axoneme assembly	1.020159e-3
GO:0072249	metanephric glomerular visceral epithelial cell development	1.041658e-3
GO:0048677	axon extension involved in regeneration	1.041658e-3
GO:0072274	metanephric glomerular basement membrane development	1.041658e-3
GO:0009443	pyridoxal 5'-phosphate salvage	1.041658e-3
GO:0045769	negative regulation of asymmetric cell division	1.041658e-3
GO:0035509	negative regulation of myosin-light-chain-phosphatase activity	1.041658e-3
GO:0043378	positive regulation of CD8-positive, alpha-beta T cell differentiation	1.041658e-3
GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity	1.063365e-3
GO:0009629	response to gravity	1.113777e-3
GO:0060850	regulation of transcription involved in cell fate commitment	1.129142e-3
GO:0060836	lymphatic endothelial cell differentiation	1.158464e-3
GO:0051568	histone H3-K4 methylation	1.226238e-3
GO:0033365	protein localization to organelle	1.227820e-3
GO:0051488	activation of anaphase-promoting complex activity	1.232517e-3
GO:0070668	positive regulation of mast cell proliferation	1.310994e-3
GO:0070171	negative regulation of tooth mineralization	1.310994e-3
GO:0018126	protein hydroxylation	1.355657e-3
GO:0072655	establishment of protein localization in mitochondrion	1.356301e-3
GO:0010225	response to UV-C	1.357621e-3
GO:0045862	positive regulation of proteolysis	1.397982e-3
GO:0060716	labyrinthine layer blood vessel development	1.435655e-3
GO:0040034	regulation of development, heterochronic	1.442007e-3
GO:0031577	spindle checkpoint	1.523731e-3
GO:0050684	regulation of mRNA processing	1.531061e-3
GO:0071353	cellular response to interleukin-4	1.631549e-3
GO:0032908	regulation of transforming growth factor beta1 production	1.631549e-3
GO:0002676	regulation of chronic inflammatory response	1.704541e-3
GO:0021897	forebrain astrocyte development	1.717166e-3
GO:0071247	cellular response to chromate	1.717166e-3
GO:0051149	positive regulation of muscle cell differentiation	1.837634e-3
GO:0050883	musculoskeletal movement, spinal reflex action	1.842493e-3
GO:0019058	viral infectious cycle	1.878550e-3
GO:0015931	nucleobase-containing compound transport	1.942073e-3
GO:0010569	regulation of double-strand break repair via homologous recombination	1.958976e-3
GO:0040032	post-embryonic body morphogenesis	1.998696e-3
GO:0031061	negative regulation of histone methylation	2.003027e-3
GO:0040029	regulation of gene expression, epigenetic	2.117668e-3
GO:0090085	regulation of protein deubiquitination	2.125307e-3
GO:0046591	embryonic leg joint morphogenesis	2.125307e-3
GO:0006108	malate metabolic process	2.218313e-3
GO:0072141	renal interstitial cell development	2.218499e-3
GO:0048384	retinoic acid receptor signaling pathway	2.225641e-3
GO:0001881	receptor recycling	2.255789e-3
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.266245e-3
GO:0071173	spindle assembly checkpoint	2.281523e-3
GO:0071108	protein K48-linked deubiquitination	2.281523e-3
GO:0030099	myeloid cell differentiation	2.356264e-3
GO:0035094	response to nicotine	2.418261e-3
GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore	2.477793e-3
GO:0000966	RNA 5'-end processing	2.477793e-3
GO:0046079	dUMP catabolic process	2.477793e-3
GO:0006412	translation	2.496398e-3
GO:0034502	protein localization to chromosome	2.658138e-3
GO:0072259	metanephric interstitial cell development	2.715066e-3
GO:0090094	metanephric cap mesenchymal cell proliferation involved in metanephros development	2.715066e-3
GO:0072208	metanephric smooth muscle tissue development	2.715066e-3
GO:0072184	renal vesicle progenitor cell differentiation	2.715066e-3
GO:0072168	specification of anterior mesonephric tubule identity	2.715066e-3
GO:0072169	specification of posterior mesonephric tubule identity	2.715066e-3
GO:0010157	response to chlorate	2.747487e-3
GO:0000414	regulation of histone H3-K36 methylation	2.885796e-3
GO:0031848	protection from non-homologous end joining at telomere	2.885796e-3
GO:0072133	metanephric mesenchyme morphogenesis	2.885796e-3
GO:0021986	habenula development	2.885796e-3
GO:0051589	negative regulation of neurotransmitter transport	2.944325e-3
GO:0046031	ADP metabolic process	2.944325e-3
GO:0014051	gamma-aminobutyric acid secretion	2.944325e-3
GO:0042147	retrograde transport, endosome to Golgi	3.001402e-3
GO:0070585	protein localization in mitochondrion	3.105432e-3
GO:0006333	chromatin assembly or disassembly	3.142636e-3
GO:0070198	protein localization to chromosome, telomeric region	3.149224e-3
GO:0055119	relaxation of cardiac muscle	3.149224e-3
GO:0006354	transcription elongation, DNA-dependent	3.151977e-3
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	3.205086e-3
GO:0008535	respiratory chain complex IV assembly	3.329383e-3
GO:0000380	alternative nuclear mRNA splicing, via spliceosome	3.329383e-3
GO:0015780	nucleotide-sugar transport	3.426085e-3
GO:0046686	response to cadmium ion	3.430460e-3
GO:0018198	peptidyl-cysteine modification	3.525761e-3
GO:0030851	granulocyte differentiation	3.532639e-3
GO:0060986	endocrine hormone secretion	3.549548e-3
GO:0031657	regulation of cyclin-dependent protein kinase activity involved in G1/S	3.610662e-3
GO:0033119	negative regulation of RNA splicing	3.613394e-3
GO:0002438	acute inflammatory response to antigenic stimulus	3.613394e-3
GO:0065001	specification of axis polarity	3.638560e-3
GO:0043951	negative regulation of cAMP-mediated signaling	3.638560e-3
GO:0035093	spermatogenesis, exchange of chromosomal proteins	3.638560e-3
GO:0021524	visceral motor neuron differentiation	3.685757e-3
GO:0021578	hindbrain maturation	3.715722e-3
GO:0001835	blastocyst hatching	3.715722e-3
GO:2000112	regulation of cellular macromolecule biosynthetic process	3.752138e-3
GO:0060014	granulosa cell differentiation	3.863166e-3
GO:0070537	histone H2A K63-linked deubiquitination	3.863166e-3
GO:0006383	transcription from RNA polymerase III promoter	3.863166e-3
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	3.888544e-3
GO:0048025	negative regulation of nuclear mRNA splicing, via spliceosome	3.903056e-3
GO:0070189	kynurenine metabolic process	3.934447e-3
GO:0051865	protein autoubiquitination	3.947837e-3
GO:0007628	adult walking behavior	3.960382e-3
GO:0006473	protein acetylation	3.986272e-3
GO:0034154	toll-like receptor 7 signaling pathway	4.048106e-3
GO:0001834	trophectodermal cell proliferation	4.048106e-3
GO:0042415	norepinephrine metabolic process	4.056901e-3
GO:0000236	mitotic prometaphase	4.216461e-3
GO:0090321	positive regulation of chylomicron remnant clearance	4.216461e-3
GO:0090319	positive regulation of chylomicron remodeling	4.216461e-3
GO:0001890	placenta development	4.346567e-3
GO:0045040	protein import into mitochondrial outer membrane	4.357829e-3
GO:0035887	aortic smooth muscle cell differentiation	4.357829e-3
GO:0070536	protein K63-linked deubiquitination	4.371670e-3
GO:0000042	protein targeting to Golgi	4.380313e-3
GO:0045056	transcytosis	4.380313e-3
GO:0033160	positive regulation of protein import into nucleus, translocation	4.420356e-3
GO:0017004	cytochrome complex assembly	4.632365e-3
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	4.669454e-3
GO:0048505	regulation of timing of cell differentiation	4.697364e-3
GO:0071423	malate transmembrane transport	4.715973e-3
GO:0015709	thiosulfate transport	4.715973e-3
GO:0014005	microglia development	4.715973e-3
GO:0009159	deoxyribonucleoside monophosphate catabolic process	4.715973e-3
GO:0031572	G2/M transition DNA damage checkpoint	4.782045e-3
GO:0051252	regulation of RNA metabolic process	4.795612e-3
GO:0072183	negative regulation of nephron tubule epithelial cell differentiation	4.833090e-3
GO:0030237	female sex determination	4.833090e-3
GO:0000189	MAPK import into nucleus	4.833090e-3
GO:0051900	regulation of mitochondrial depolarization	4.874994e-3
GO:0018205	peptidyl-lysine modification	4.895728e-3
GO:0048625	myoblast cell fate commitment	5.017779e-3
GO:0060019	radial glial cell differentiation	5.044090e-3
GO:0051935	glutamate uptake involved in synaptic transmission	5.081887e-3
GO:0000281	cytokinesis after mitosis	5.081887e-3
GO:0043543	protein acylation	5.151289e-3
GO:0071174	mitotic cell cycle spindle checkpoint	5.162486e-3
GO:0030854	positive regulation of granulocyte differentiation	5.232116e-3
GO:0051053	negative regulation of DNA metabolic process	5.361638e-3
GO:0006044	N-acetylglucosamine metabolic process	5.369182e-3
GO:0050849	negative regulation of calcium-mediated signaling	5.567012e-3
GO:0051572	negative regulation of histone H3-K4 methylation	5.567012e-3
GO:0031060	regulation of histone methylation	5.647048e-3
GO:0015816	glycine transport	5.654442e-3
GO:0045494	photoreceptor cell maintenance	5.721886e-3
GO:0030522	intracellular receptor mediated signaling pathway	5.773337e-3
GO:0002262	myeloid cell homeostasis	5.800674e-3
GO:0001522	pseudouridine synthesis	5.896608e-3
GO:0001829	trophectodermal cell differentiation	6.006055e-3
GO:0021522	spinal cord motor neuron differentiation	6.041564e-3
GO:0006422	aspartyl-tRNA aminoacylation	6.212487e-3
GO:0046356	acetyl-CoA catabolic process	6.228668e-3
GO:0030223	neutrophil differentiation	6.357471e-3
GO:0070170	regulation of tooth mineralization	6.357471e-3
GO:0060713	labyrinthine layer morphogenesis	6.503036e-3
GO:0046007	negative regulation of activated T cell proliferation	6.509712e-3
GO:0000045	autophagic vacuole assembly	6.553292e-3
GO:0018193	peptidyl-amino acid modification	6.663553e-3
GO:0016584	nucleosome positioning	6.694174e-3
GO:0010458	exit from mitosis	6.694174e-3
GO:0034621	cellular macromolecular complex subunit organization	6.762683e-3
GO:0006172	ADP biosynthetic process	6.770256e-3
GO:0045089	positive regulation of innate immune response	6.940818e-3
GO:0032204	regulation of telomere maintenance	7.286323e-3
GO:0019067	viral assembly, maturation, egress, and release	7.286323e-3
GO:0048066	developmental pigmentation	7.520888e-3
GO:0014056	regulation of acetylcholine secretion	7.811015e-3
GO:0018243	protein O-linked glycosylation via threonine	7.846318e-3
GO:0018242	protein O-linked glycosylation via serine	7.846318e-3
GO:0019408	dolichol biosynthetic process	7.855303e-3
GO:2000299	negative regulation of Rho-dependent protein serine/threonine kinase activity	7.855303e-3
GO:0032853	positive regulation of Ran GTPase activity	7.855303e-3
GO:0015887	pantothenate transmembrane transport	7.855303e-3
GO:0015878	biotin transport	7.855303e-3
GO:0000115	regulation of transcription involved in S phase of mitotic cell cycle	7.855303e-3
GO:0006427	histidyl-tRNA aminoacylation	7.855303e-3
GO:0009786	regulation of asymmetric cell division	7.855303e-3
GO:0060376	positive regulation of mast cell differentiation	7.898993e-3
GO:0072553	terminal button organization	7.898993e-3
GO:0018095	protein polyglutamylation	7.898993e-3
GO:0042360	vitamin E metabolic process	7.898993e-3
GO:0009109	coenzyme catabolic process	7.953047e-3
GO:0032911	negative regulation of transforming growth factor beta1 production	7.965520e-3
GO:0060333	interferon-gamma-mediated signaling pathway	8.151124e-3
GO:0021918	regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment	8.151124e-3
GO:0003322	pancreatic A cell development	8.151124e-3
GO:0021905	forebrain-midbrain boundary formation	8.151124e-3
GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	8.151124e-3
GO:0072594	establishment of protein localization to organelle	8.179716e-3
GO:0016572	histone phosphorylation	8.197770e-3
GO:0014002	astrocyte development	8.253464e-3
GO:0034660	ncRNA metabolic process	8.269155e-3
GO:0048821	erythrocyte development	8.359343e-3
GO:0045840	positive regulation of mitosis	8.572635e-3
GO:0001833	inner cell mass cell proliferation	8.642950e-3
GO:0051386	regulation of nerve growth factor receptor signaling pathway	8.746761e-3
GO:0030031	cell projection assembly	8.845723e-3
GO:0000413	protein peptidyl-prolyl isomerization	8.880063e-3
GO:0051457	maintenance of protein location in nucleus	8.920305e-3
GO:0060282	positive regulation of oocyte development	8.928508e-3
GO:0060281	regulation of oocyte development	8.928508e-3
GO:0000723	telomere maintenance	9.210463e-3
GO:0035195	gene silencing by miRNA	9.554659e-3
GO:0021520	spinal cord motor neuron cell fate specification	9.613500e-3
GO:0000301	retrograde transport, vesicle recycling within Golgi	9.613500e-3
GO:0006119	oxidative phosphorylation	9.613500e-3
GO:0090084	negative regulation of inclusion body assembly	9.723077e-3
GO:0008334	histone mRNA metabolic process	1.001340e-2
GO:0043923	positive regulation by host of viral transcription	1.001340e-2
GO:0061136	regulation of proteasomal protein catabolic process	1.013444e-2
GO:0046671	negative regulation of retinal cell programmed cell death	1.031133e-2
GO:0006283	transcription-coupled nucleotide-excision repair	1.031133e-2
GO:0006355	regulation of transcription, DNA-dependent	1.041191e-2
GO:0046755	non-lytic virus budding	1.049668e-2
GO:0071673	positive regulation of smooth muscle cell chemotaxis	1.049668e-2
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	1.049668e-2
GO:0043393	regulation of protein binding	1.065642e-2
GO:0016570	histone modification	1.068843e-2
GO:0051574	positive regulation of histone H3-K9 methylation	1.077624e-2
GO:0042773	ATP synthesis coupled electron transport	1.080591e-2
GO:0006620	posttranslational protein targeting to membrane	1.080591e-2
GO:0021548	pons development	1.087627e-2
GO:0006099	tricarboxylic acid cycle	1.114157e-2
GO:0034067	protein localization in Golgi apparatus	1.142729e-2
GO:0021523	somatic motor neuron differentiation	1.142729e-2
GO:0010107	potassium ion import	1.149924e-2
GO:0055118	negative regulation of cardiac muscle contraction	1.151528e-2
GO:0051895	negative regulation of focal adhesion assembly	1.151528e-2
GO:0072148	epithelial cell fate commitment	1.179573e-2
GO:0035886	vascular smooth muscle cell differentiation	1.189903e-2
GO:0014040	positive regulation of Schwann cell differentiation	1.196201e-2
GO:0051461	positive regulation of corticotropin secretion	1.196201e-2
GO:0048936	peripheral nervous system neuron axonogenesis	1.196505e-2
GO:0045818	negative regulation of glycogen catabolic process	1.196505e-2
GO:0051036	regulation of endosome size	1.196505e-2
GO:0001987	vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure	1.196505e-2
GO:0032543	mitochondrial translation	1.196505e-2
GO:0015761	mannose transport	1.196505e-2
GO:0046627	negative regulation of insulin receptor signaling pathway	1.197497e-2
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	1.198302e-2
GO:0042335	cuticle development	1.210190e-2
GO:0034470	ncRNA processing	1.233009e-2
GO:0006493	protein O-linked glycosylation	1.241493e-2
GO:0048704	embryonic skeletal system morphogenesis	1.242618e-2
GO:2000467	positive regulation of glycogen (starch) synthase activity	1.251218e-2
GO:0072595	maintenance of protein localization to organelle	1.251558e-2
GO:0050434	positive regulation of viral transcription	1.278396e-2
GO:0031102	neuron projection regeneration	1.279914e-2
GO:0019400	alditol metabolic process	1.315746e-2
GO:0001709	cell fate determination	1.327178e-2
GO:0060674	placenta blood vessel development	1.327290e-2
GO:0010224	response to UV-B	1.328406e-2
GO:0032516	positive regulation of phosphoprotein phosphatase activity	1.335036e-2
GO:0034622	cellular macromolecular complex assembly	1.336514e-2
GO:0071895	odontoblast differentiation	1.340804e-2
GO:0016090	prenol metabolic process	1.340804e-2
GO:0043654	recognition of apoptotic cell	1.340804e-2
GO:0044265	cellular macromolecule catabolic process	1.348681e-2
GO:0007403	glial cell fate determination	1.349230e-2
GO:0046544	development of secondary male sexual characteristics	1.349230e-2
GO:0051013	microtubule severing	1.349230e-2
GO:0034214	protein hexamerization	1.349230e-2
GO:0072203	cell proliferation involved in metanephros development	1.353796e-2
GO:0009179	purine ribonucleoside diphosphate metabolic process	1.353796e-2
GO:0030825	positive regulation of cGMP metabolic process	1.353796e-2
GO:0010722	regulation of ferrochelatase activity	1.358823e-2
GO:0042699	follicle-stimulating hormone signaling pathway	1.360945e-2
GO:0021517	ventral spinal cord development	1.365052e-2
GO:0001578	microtubule bundle formation	1.409569e-2
GO:0046069	cGMP catabolic process	1.420393e-2
GO:0060045	positive regulation of cardiac muscle cell proliferation	1.431624e-2
GO:0043414	macromolecule methylation	1.432039e-2
GO:0048706	embryonic skeletal system development	1.444346e-2
GO:0021997	neural plate axis specification	1.448318e-2
GO:0010834	telomere maintenance via telomere shortening	1.448318e-2
GO:0046628	positive regulation of insulin receptor signaling pathway	1.458544e-2
GO:0055075	potassium ion homeostasis	1.461525e-2
GO:0007094	mitotic cell cycle spindle assembly checkpoint	1.461525e-2
GO:0016568	chromatin modification	1.469336e-2
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	1.469360e-2
GO:0042271	susceptibility to natural killer cell mediated cytotoxicity	1.469360e-2
GO:0002524	hypersensitivity	1.488942e-2
GO:0032648	regulation of interferon-beta production	1.506134e-2
GO:0015812	gamma-aminobutyric acid transport	1.549866e-2
GO:0032859	activation of Ral GTPase activity	1.551419e-2
GO:0010468	regulation of gene expression	1.585030e-2
GO:2000779	regulation of double-strand break repair	1.593332e-2
GO:0015074	DNA integration	1.602763e-2
GO:0010556	regulation of macromolecule biosynthetic process	1.609490e-2
GO:0071480	cellular response to gamma radiation	1.613500e-2
GO:0071360	cellular response to exogenous dsRNA	1.613500e-2
GO:0030644	cellular chloride ion homeostasis	1.613500e-2
GO:0016540	protein autoprocessing	1.637391e-2
GO:0016569	covalent chromatin modification	1.644743e-2
GO:0006364	rRNA processing	1.649384e-2
GO:0032200	telomere organization	1.668710e-2
GO:0046006	regulation of activated T cell proliferation	1.676026e-2
GO:0031062	positive regulation of histone methylation	1.687989e-2
GO:0006612	protein targeting to membrane	1.699826e-2
GO:0070885	negative regulation of calcineurin-NFAT signaling pathway	1.708900e-2
GO:0010045	response to nickel ion	1.708900e-2
GO:0070625	zymogen granule exocytosis	1.708900e-2
GO:0035459	cargo loading into vesicle	1.708900e-2
GO:0016598	protein arginylation	1.708900e-2
GO:0032226	positive regulation of synaptic transmission, dopaminergic	1.720181e-2
GO:0006059	hexitol metabolic process	1.720181e-2
GO:2000286	receptor internalization involved in canonical Wnt receptor signaling pathway	1.733702e-2
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	1.733702e-2
GO:0006561	proline biosynthetic process	1.733702e-2
GO:0042552	myelination	1.737496e-2
GO:0032912	negative regulation of transforming growth factor beta2 production	1.760066e-2
GO:0035110	leg morphogenesis	1.767853e-2
GO:0008366	axon ensheathment	1.791331e-2
GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.817709e-2
GO:0019673	GDP-mannose metabolic process	1.817709e-2
GO:0018200	peptidyl-glutamic acid modification	1.820802e-2
GO:0048570	notochord morphogenesis	1.828006e-2
GO:0090083	regulation of inclusion body assembly	1.828006e-2
GO:0021545	cranial nerve development	1.833411e-2
GO:0021778	oligodendrocyte cell fate specification	1.835090e-2
GO:0006366	transcription from RNA polymerase II promoter	1.837179e-2
GO:0035067	negative regulation of histone acetylation	1.863229e-2
GO:0021535	cell migration in hindbrain	1.869793e-2
GO:0048872	homeostasis of number of cells	1.885634e-2
GO:0001937	negative regulation of endothelial cell proliferation	1.904191e-2
GO:0070647	protein modification by small protein conjugation or removal	1.915683e-2
GO:0070972	protein localization in endoplasmic reticulum	1.974790e-2
GO:0006353	transcription termination, DNA-dependent	1.987688e-2
GO:0071635	negative regulation of transforming growth factor beta production	1.991487e-2
GO:0035116	embryonic hindlimb morphogenesis	2.017665e-2
GO:0045943	positive regulation of transcription from RNA polymerase I promoter	2.033977e-2
GO:0070166	enamel mineralization	2.053935e-2
GO:0006312	mitotic recombination	2.053935e-2
GO:0070925	organelle assembly	2.062974e-2
GO:0055021	regulation of cardiac muscle tissue growth	2.082271e-2
GO:0060043	regulation of cardiac muscle cell proliferation	2.087725e-2
GO:0021796	cerebral cortex regionalization	2.089114e-2
GO:0000387	spliceosomal snRNP assembly	2.089114e-2