Novel motif:85

name:	motif85_TWNNGCSNA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0006261	DNA-dependent DNA replication	3.550965e-10
GO:0042254	ribosome biogenesis	8.552938e-10
GO:0022616	DNA strand elongation	1.296524e-9
GO:0051320	S phase	7.059854e-9
GO:0006271	DNA strand elongation involved in DNA replication	1.034905e-8
GO:0000084	S phase of mitotic cell cycle	5.734235e-8
GO:0034470	ncRNA processing	9.643640e-8
GO:0060236	regulation of mitotic spindle organization	1.039478e-7
GO:0016072	rRNA metabolic process	1.426643e-7
GO:0030488	tRNA methylation	1.628215e-7
GO:0030683	evasion by virus of host immune response	2.647720e-7
GO:0006406	mRNA export from nucleus	2.971740e-7
GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	3.513720e-7
GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	3.513720e-7
GO:0006396	RNA processing	3.668932e-7
GO:0034660	ncRNA metabolic process	3.671607e-7
GO:0022613	ribonucleoprotein complex biogenesis	5.036346e-7
GO:0001980	regulation of systemic arterial blood pressure by ischemic conditions	5.087186e-7
GO:0014005	microglia development	6.398914e-7
GO:0001510	RNA methylation	8.342221e-7
GO:0032201	telomere maintenance via semi-conservative replication	8.418763e-7
GO:0006379	mRNA cleavage	1.412704e-6
GO:0080009	mRNA methylation	1.762152e-6
GO:0042747	circadian sleep/wake cycle, REM sleep	1.762152e-6
GO:0090305	nucleic acid phosphodiester bond hydrolysis	1.763897e-6
GO:0009451	RNA modification	1.827237e-6
GO:0051083	'de novo' cotranslational protein folding	1.869873e-6
GO:0071843	cellular component biogenesis at cellular level	2.727780e-6
GO:0000730	DNA recombinase assembly	2.850110e-6
GO:0046939	nucleotide phosphorylation	2.863039e-6
GO:0006281	DNA repair	3.263741e-6
GO:0006405	RNA export from nucleus	3.559175e-6
GO:0015693	magnesium ion transport	3.647414e-6
GO:0000722	telomere maintenance via recombination	4.168695e-6
GO:0033566	gamma-tubulin complex localization	4.394076e-6
GO:0006844	acyl carnitine transport	4.546906e-6
GO:0032074	negative regulation of nuclease activity	4.724462e-6
GO:0016071	mRNA metabolic process	5.386627e-6
GO:0006297	nucleotide-excision repair, DNA gap filling	5.880219e-6
GO:0006364	rRNA processing	6.489550e-6
GO:0006370	mRNA capping	7.631368e-6
GO:0006289	nucleotide-excision repair	7.649048e-6
GO:0009386	translational attenuation	7.993346e-6
GO:0061316	canonical Wnt receptor signaling pathway involved in heart development	8.356064e-6
GO:0060816	random inactivation of X chromosome	1.115087e-5
GO:0000724	double-strand break repair via homologous recombination	1.279319e-5
GO:0008216	spermidine metabolic process	1.380568e-5
GO:0048075	positive regulation of eye pigmentation	1.380568e-5
GO:0006458	'de novo' protein folding	1.515750e-5
GO:0000076	DNA replication checkpoint	1.569126e-5
GO:0000725	recombinational repair	1.621282e-5
GO:0009452	RNA capping	1.948986e-5
GO:0051028	mRNA transport	2.046531e-5
GO:0000723	telomere maintenance	2.350429e-5
GO:0006312	mitotic recombination	2.474173e-5
GO:0000080	G1 phase of mitotic cell cycle	2.524663e-5
GO:0071156	regulation of cell cycle arrest	2.653423e-5
GO:0032312	regulation of ARF GTPase activity	2.724061e-5
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	2.789718e-5
GO:0000917	barrier septum formation	2.977390e-5
GO:0007127	meiosis I	3.029497e-5
GO:0050747	positive regulation of lipoprotein metabolic process	3.059686e-5
GO:0090162	establishment of epithelial cell polarity	3.083818e-5
GO:0043456	regulation of pentose-phosphate shunt	3.241195e-5
GO:0042270	protection from natural killer cell mediated cytotoxicity	3.399119e-5
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	3.547796e-5
GO:0000389	nuclear mRNA 3'-splice site recognition	3.686575e-5
GO:0010498	proteasomal protein catabolic process	5.435900e-5
GO:0044265	cellular macromolecule catabolic process	5.616653e-5
GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis	5.617563e-5
GO:0033342	negative regulation of collagen binding	5.639108e-5
GO:0021943	formation of radial glial scaffolds	5.899828e-5
GO:0034509	centromeric core chromatin assembly	5.910838e-5
GO:0000216	M/G1 transition of mitotic cell cycle	5.962547e-5
GO:0050658	RNA transport	5.983135e-5
GO:0048073	regulation of eye pigmentation	6.055706e-5
GO:0001830	trophectodermal cell fate commitment	6.102608e-5
GO:0030322	stabilization of membrane potential	6.102608e-5
GO:0006310	DNA recombination	6.423274e-5
GO:0006284	base-excision repair	6.659492e-5
GO:0030206	chondroitin sulfate biosynthetic process	6.759910e-5
GO:0042771	DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis	7.183214e-5
GO:0031118	rRNA pseudouridine synthesis	7.327834e-5
GO:0060019	radial glial cell differentiation	7.679679e-5
GO:0051546	keratinocyte migration	8.053283e-5
GO:0010833	telomere maintenance via telomere lengthening	8.123722e-5
GO:0016032	viral reproduction	8.127948e-5
GO:0016180	snRNA processing	8.179355e-5
GO:0070192	chromosome organization involved in meiosis	8.426745e-5
GO:0006260	DNA replication	8.800220e-5
GO:0034241	positive regulation of macrophage fusion	8.868271e-5
GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	8.868271e-5
GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	8.868271e-5
GO:0006534	cysteine metabolic process	9.050574e-5
GO:0007614	short-term memory	9.399296e-5
GO:0006403	RNA localization	9.734291e-5
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	9.939199e-5
GO:0032790	ribosome disassembly	9.939199e-5
GO:0071816	tail-anchored membrane protein insertion into ER membrane	1.047383e-4
GO:0000075	cell cycle checkpoint	1.079993e-4
GO:0035659	Wnt receptor signaling pathway involved in wound healing, spreading of epidermal cells	1.100758e-4
GO:0014719	satellite cell activation	1.100758e-4
GO:0032200	telomere organization	1.192962e-4
GO:0003016	respiratory system process	1.216013e-4
GO:0006414	translational elongation	1.265501e-4
GO:0045008	depyrimidination	1.417819e-4
GO:0006308	DNA catabolic process	1.458295e-4
GO:0042770	signal transduction in response to DNA damage	1.535954e-4
GO:0030208	dermatan sulfate biosynthetic process	1.563891e-4
GO:0065002	intracellular protein transmembrane transport	1.655549e-4
GO:0070086	ubiquitin-dependent endocytosis	1.938250e-4
GO:0016073	snRNA metabolic process	2.324050e-4
GO:0031497	chromatin assembly	2.436643e-4
GO:0060066	oviduct development	2.440898e-4
GO:0051106	positive regulation of DNA ligation	2.476979e-4
GO:0097037	heme export	2.476979e-4
GO:0019079	viral genome replication	2.508147e-4
GO:2000016	negative regulation of determination of dorsal identity	2.728703e-4
GO:0008295	spermidine biosynthetic process	2.728703e-4
GO:0030330	DNA damage response, signal transduction by p53 class mediator	2.822498e-4
GO:0032863	activation of Rac GTPase activity	2.883296e-4
GO:0016556	mRNA modification	2.975629e-4
GO:0018345	protein palmitoylation	3.015577e-4
GO:0030903	notochord development	3.128795e-4
GO:0031125	rRNA 3'-end processing	3.133214e-4
GO:0030163	protein catabolic process	3.182784e-4
GO:0071028	nuclear mRNA surveillance	3.257369e-4
GO:0030421	defecation	3.257369e-4
GO:0006777	Mo-molybdopterin cofactor biosynthetic process	3.282174e-4
GO:0021932	hindbrain radial glia guided cell migration	3.348320e-4
GO:0006283	transcription-coupled nucleotide-excision repair	3.399086e-4
GO:0051318	G1 phase	3.466651e-4
GO:0007128	meiotic prophase I	3.646257e-4
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	3.817109e-4
GO:0006259	DNA metabolic process	4.051532e-4
GO:0019083	viral transcription	4.148024e-4
GO:0003308	negative regulation of Wnt receptor signaling pathway involved in heart development	4.387442e-4
GO:0060992	response to fungicide	4.487074e-4
GO:0000077	DNA damage checkpoint	4.885301e-4
GO:0003136	negative regulation of heart induction by canonical Wnt receptor signaling pathway	5.029474e-4
GO:0060035	notochord cell development	5.092390e-4
GO:0031570	DNA integrity checkpoint	5.132522e-4
GO:0090224	regulation of spindle organization	5.153404e-4
GO:0030204	chondroitin sulfate metabolic process	5.167948e-4
GO:0000236	mitotic prometaphase	5.183946e-4
GO:0035136	forelimb morphogenesis	5.250065e-4
GO:0035115	embryonic forelimb morphogenesis	5.312530e-4
GO:0021681	cerebellar granular layer development	5.687087e-4
GO:0031848	protection from non-homologous end joining at telomere	5.697724e-4
GO:0071158	positive regulation of cell cycle arrest	5.805102e-4
GO:0006974	response to DNA damage stimulus	5.852552e-4
GO:0051531	NFAT protein import into nucleus	5.912740e-4
GO:0010933	positive regulation of macrophage tolerance induction	6.092375e-4
GO:0006051	N-acetylmannosamine metabolic process	6.092375e-4
GO:0003222	ventricular trabecular myocardium morphogenesis	6.268427e-4
GO:0045063	T-helper 1 cell differentiation	6.280544e-4
GO:0046782	regulation of viral transcription	6.342998e-4
GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	6.428957e-4
GO:0046500	S-adenosylmethionine metabolic process	6.651685e-4
GO:0019058	viral infectious cycle	6.724453e-4
GO:0043921	modulation by host of viral transcription	6.937527e-4
GO:0040032	post-embryonic body morphogenesis	7.252564e-4
GO:0051225	spindle assembly	7.386022e-4
GO:0006415	translational termination	7.472632e-4
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	7.605671e-4
GO:0009223	pyrimidine deoxyribonucleotide catabolic process	8.150495e-4
GO:0043632	modification-dependent macromolecule catabolic process	8.337181e-4
GO:0032780	negative regulation of ATPase activity	8.350504e-4
GO:0043628	ncRNA 3'-end processing	8.592153e-4
GO:0043181	vacuolar sequestering	8.856608e-4
GO:0035621	ER to Golgi ceramide transport	8.856608e-4
GO:0000023	maltose metabolic process	8.856608e-4
GO:0005985	sucrose metabolic process	8.856608e-4
GO:0061084	negative regulation of protein refolding	8.954872e-4
GO:0033590	response to cobalamin	9.242272e-4
GO:0006117	acetaldehyde metabolic process	9.242272e-4
GO:0050434	positive regulation of viral transcription	9.632254e-4
GO:0007129	synapsis	9.698713e-4
GO:0060741	prostate gland stromal morphogenesis	9.777323e-4
GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain	1.002190e-3
GO:0031860	telomeric 3' overhang formation	1.081775e-3
GO:0018192	enzyme active site formation via L-cysteine persulfide	1.081775e-3
GO:0009446	putrescine biosynthetic process	1.081775e-3
GO:0015761	mannose transport	1.081775e-3
GO:0000022	mitotic spindle elongation	1.108508e-3
GO:0048102	autophagic cell death	1.139979e-3
GO:0003307	regulation of Wnt receptor signaling pathway involved in heart development	1.143493e-3
GO:0071638	negative regulation of monocyte chemotactic protein-1 production	1.239873e-3
GO:0035732	nitric oxide storage	1.239873e-3
GO:0031468	nuclear envelope reassembly	1.239873e-3
GO:0035726	common myeloid progenitor cell proliferation	1.239873e-3
GO:0035083	cilium axoneme assembly	1.274107e-3
GO:0051324	prophase	1.282647e-3
GO:0010520	regulation of reciprocal meiotic recombination	1.319674e-3
GO:0032682	negative regulation of chemokine production	1.319674e-3
GO:0071394	cellular response to testosterone stimulus	1.353381e-3
GO:0019448	L-cysteine catabolic process	1.353381e-3
GO:0006313	transposition, DNA-mediated	1.353381e-3
GO:0008334	histone mRNA metabolic process	1.362330e-3
GO:0019941	modification-dependent protein catabolic process	1.370185e-3
GO:0009057	macromolecule catabolic process	1.378073e-3
GO:0071726	cellular response to diacyl bacterial lipopeptide	1.409522e-3
GO:0042496	detection of diacyl bacterial lipopeptide	1.409522e-3
GO:0043923	positive regulation by host of viral transcription	1.454346e-3
GO:0070863	positive regulation of protein exit from endoplasmic reticulum	1.464701e-3
GO:0021861	forebrain radial glial cell differentiation	1.493498e-3
GO:0006511	ubiquitin-dependent protein catabolic process	1.503328e-3
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	1.509183e-3
GO:0043105	negative regulation of GTP cyclohydrolase I activity	1.517601e-3
GO:0007007	inner mitochondrial membrane organization	1.534539e-3
GO:0046590	embryonic leg morphogenesis	1.543650e-3
GO:0072404	signal transduction involved in G1/S transition checkpoint	1.557261e-3
GO:0071025	RNA surveillance	1.560200e-3
GO:0014028	notochord formation	1.560200e-3
GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis	1.682418e-3
GO:0070060	'de novo' actin filament nucleation	1.682418e-3
GO:0006400	tRNA modification	1.763553e-3
GO:0051084	'de novo' posttranslational protein folding	1.799520e-3
GO:0072422	signal transduction involved in DNA damage checkpoint	1.820656e-3
GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	1.828839e-3
GO:0014908	myotube differentiation involved in skeletal muscle regeneration	1.838147e-3
GO:0072395	signal transduction involved in cell cycle checkpoint	1.873147e-3
GO:0006333	chromatin assembly or disassembly	1.879632e-3
GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	1.891172e-3
GO:0000244	assembly of spliceosomal tri-snRNP	1.903628e-3
GO:0001696	gastric acid secretion	1.907603e-3
GO:0000718	nucleotide-excision repair, DNA damage removal	1.926427e-3
GO:0034976	response to endoplasmic reticulum stress	1.970556e-3
GO:0060381	positive regulation of single-stranded telomeric DNA binding	2.047381e-3
GO:0006244	pyrimidine nucleotide catabolic process	2.101729e-3
GO:0065004	protein-DNA complex assembly	2.124569e-3
GO:0051603	proteolysis involved in cellular protein catabolic process	2.135996e-3
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	2.139618e-3
GO:0050654	chondroitin sulfate proteoglycan metabolic process	2.169881e-3
GO:0007212	dopamine receptor signaling pathway	2.206506e-3
GO:0090244	Wnt receptor signaling pathway involved in somitogenesis	2.219567e-3
GO:0015931	nucleobase-containing compound transport	2.229523e-3
GO:0071727	cellular response to triacyl bacterial lipopeptide	2.311261e-3
GO:0042495	detection of triacyl bacterial lipopeptide	2.311261e-3
GO:0006482	protein demethylation	2.468957e-3
GO:0046967	cytosol to ER transport	2.477792e-3
GO:0070307	lens fiber cell development	2.501693e-3
GO:0019532	oxalate transport	2.537046e-3
GO:0071895	odontoblast differentiation	2.537046e-3
GO:0044257	cellular protein catabolic process	2.667194e-3
GO:0006285	base-excision repair, AP site formation	2.779952e-3
GO:0035986	senescence-associated heterochromatin focus formation	2.789342e-3
GO:2000774	positive regulation of cellular senescence	2.789342e-3
GO:0006393	termination of mitochondrial transcription	2.855830e-3
GO:0048291	isotype switching to IgG isotypes	2.855830e-3
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	2.855830e-3
GO:0002368	B cell cytokine production	2.855830e-3
GO:0019346	transsulfuration	2.874010e-3
GO:0043418	homocysteine catabolic process	2.874010e-3
GO:0006535	cysteine biosynthetic process from serine	2.874010e-3
GO:0019343	cysteine biosynthetic process via cystathionine	2.874010e-3
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	2.986000e-3
GO:0002031	G-protein coupled receptor internalization	2.986000e-3
GO:0070340	detection of bacterial lipopeptide	3.040867e-3
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	3.115781e-3
GO:0061324	canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation	3.117391e-3
GO:0034629	cellular protein complex localization	3.143342e-3
GO:0071824	protein-DNA complex subunit organization	3.179491e-3
GO:0006353	transcription termination, DNA-dependent	3.184742e-3
GO:0051256	spindle midzone assembly involved in mitosis	3.294844e-3
GO:0003306	Wnt receptor signaling pathway involved in heart development	3.302702e-3
GO:0032741	positive regulation of interleukin-18 production	3.320699e-3
GO:0046931	pore complex assembly	3.348535e-3
GO:0072331	signal transduction by p53 class mediator	3.413726e-3
GO:0034728	nucleosome organization	3.468582e-3
GO:0046323	glucose import	3.493624e-3
GO:0032049	cardiolipin biosynthetic process	3.529553e-3
GO:0051414	response to cortisol stimulus	3.549117e-3
GO:0014834	satellite cell maintenance involved in skeletal muscle regeneration	3.620374e-3
GO:2000162	negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis	3.643195e-3
GO:2000166	negative regulation of planar cell polarity pathway involved in pericardium morphogenesis	3.643195e-3
GO:2000168	negative regulation of planar cell polarity pathway involved in neural tube closure	3.643195e-3
GO:2000151	negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	3.643195e-3
GO:2000164	negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis	3.643195e-3
GO:0009231	riboflavin biosynthetic process	3.643195e-3
GO:0061310	canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development	3.643195e-3
GO:2000055	positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	3.643195e-3
GO:2000149	negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis	3.643195e-3
GO:0045655	regulation of monocyte differentiation	3.644229e-3
GO:0015868	purine ribonucleotide transport	3.690269e-3
GO:0070059	apoptosis in response to endoplasmic reticulum stress	3.730196e-3
GO:0051168	nuclear export	3.769048e-3
GO:0034623	cellular macromolecular complex disassembly	3.889931e-3
GO:0000966	RNA 5'-end processing	3.903420e-3
GO:0016233	telomere capping	3.940835e-3
GO:2000015	regulation of determination of dorsal identity	4.058339e-3
GO:0031133	regulation of axon diameter	4.058339e-3
GO:0031297	replication fork processing	4.065107e-3
GO:0006334	nucleosome assembly	4.134622e-3
GO:0018184	protein polyamination	4.159896e-3
GO:0002033	vasodilation by angiotensin involved in regulation of systemic arterial blood pressure	4.159896e-3
GO:0048715	negative regulation of oligodendrocyte differentiation	4.272029e-3
GO:0030223	neutrophil differentiation	4.283043e-3
GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	4.355614e-3
GO:0009219	pyrimidine deoxyribonucleotide metabolic process	4.379655e-3
GO:0008033	tRNA processing	4.419421e-3
GO:0031629	synaptic vesicle fusion to presynaptic membrane	4.434585e-3
GO:0031397	negative regulation of protein ubiquitination	4.503439e-3
GO:0070537	histone H2A K63-linked deubiquitination	4.540833e-3
GO:2000786	positive regulation of autophagic vacuole assembly	4.540833e-3
GO:0090245	axis elongation involved in somitogenesis	4.540833e-3
GO:0021874	Wnt receptor signaling pathway involved in forebrain neuroblast division	4.540833e-3
GO:0070358	actin polymerization-dependent cell motility	4.540833e-3
GO:0010891	negative regulation of sequestering of triglyceride	4.605736e-3
GO:0032392	DNA geometric change	4.624694e-3
GO:0060282	positive regulation of oocyte development	4.647972e-3
GO:0090304	nucleic acid metabolic process	4.677712e-3
GO:0048320	axial mesoderm formation	4.831137e-3
GO:0050746	regulation of lipoprotein metabolic process	4.843696e-3
GO:0046755	non-lytic virus budding	4.868105e-3
GO:0016577	histone demethylation	5.160751e-3
GO:0006983	ER overload response	5.432164e-3
GO:0048524	positive regulation of viral reproduction	5.557638e-3
GO:0044335	canonical Wnt receptor signaling pathway involved in neural crest cell differentiation	5.576053e-3
GO:0051292	nuclear pore complex assembly	5.576053e-3
GO:0046341	CDP-diacylglycerol metabolic process	5.576053e-3
GO:0043316	cytotoxic T cell degranulation	5.576053e-3
GO:0034314	Arp2/3 complex-mediated actin nucleation	5.576053e-3
GO:0042727	flavin-containing compound biosynthetic process	5.576053e-3
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	5.638376e-3
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	5.656881e-3
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	5.656881e-3
GO:0070602	regulation of centromeric sister chromatid cohesion	5.711232e-3
GO:0007191	activation of adenylate cyclase activity by dopamine receptor signaling pathway	5.736448e-3
GO:0046604	positive regulation of mitotic centrosome separation	5.771255e-3
GO:0046501	protoporphyrinogen IX metabolic process	6.169219e-3
GO:0051851	modification by host of symbiont morphology or physiology	6.198928e-3
GO:0051890	regulation of cardioblast differentiation	6.304442e-3
GO:2000772	regulation of cellular senescence	6.323652e-3
GO:0000387	spliceosomal snRNP assembly	6.324005e-3
GO:2000053	regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	6.339987e-3
GO:0032930	positive regulation of superoxide anion generation	6.339987e-3
GO:0021794	thalamus development	6.343772e-3
GO:0060743	epithelial cell maturation involved in prostate gland development	6.343772e-3
GO:0090343	positive regulation of cell aging	6.347755e-3
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	6.492932e-3
GO:0032988	ribonucleoprotein complex disassembly	6.521343e-3
GO:0097029	mature dendritic cell differentiation	6.531568e-3
GO:0071872	cellular response to epinephrine stimulus	6.531568e-3
GO:0009394	2'-deoxyribonucleotide metabolic process	6.572708e-3
GO:0021879	forebrain neuron differentiation	6.605352e-3
GO:0031442	positive regulation of mRNA 3'-end processing	6.721665e-3
GO:0002678	positive regulation of chronic inflammatory response	6.721665e-3
GO:0044342	type B pancreatic cell proliferation	6.757506e-3
GO:0015789	UDP-N-acetylgalactosamine transport	6.757506e-3
GO:0010918	positive regulation of mitochondrial membrane potential	6.757506e-3
GO:0015787	UDP-glucuronic acid transport	6.757506e-3
GO:0010889	regulation of sequestering of triglyceride	6.758532e-3
GO:0097039	protein linear polyubiquitination	6.912038e-3
GO:0072332	signal transduction by p53 class mediator resulting in induction of apoptosis	6.920213e-3
GO:0046498	S-adenosylhomocysteine metabolic process	6.944214e-3
GO:0033148	positive regulation of estrogen receptor signaling pathway	6.944214e-3
GO:0016137	glycoside metabolic process	7.013423e-3
GO:0000380	alternative nuclear mRNA splicing, via spliceosome	7.013423e-3
GO:0022415	viral reproductive process	7.043218e-3
GO:0035137	hindlimb morphogenesis	7.085521e-3
GO:0032984	macromolecular complex disassembly	7.118100e-3
GO:0044340	canonical Wnt receptor signaling pathway involved in regulation of cell proliferation	7.172007e-3
GO:0006369	termination of RNA polymerase II transcription	7.210191e-3
GO:0051444	negative regulation of ubiquitin-protein ligase activity	7.381837e-3
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	7.496734e-3
GO:0070159	mitochondrial threonyl-tRNA aminoacylation	7.707012e-3
GO:2000251	positive regulation of actin cytoskeleton reorganization	7.717459e-3
GO:0045065	cytotoxic T cell differentiation	7.717459e-3
GO:0006734	NADH metabolic process	7.841579e-3
GO:0021773	striatal medium spiny neuron differentiation	7.869493e-3
GO:0019060	intracellular transport of viral proteins in host cell	7.869493e-3
GO:0070193	synaptonemal complex organization	7.918339e-3
GO:0060738	epithelial-mesenchymal signaling involved in prostate gland development	8.110838e-3
GO:0051712	positive regulation of killing of cells of other organism	8.110838e-3
GO:0090342	regulation of cell aging	8.151170e-3
GO:0021872	forebrain generation of neurons	8.171087e-3
GO:0090307	spindle assembly involved in mitosis	8.534136e-3
GO:0001514	selenocysteine incorporation	8.534136e-3
GO:0043922	negative regulation by host of viral transcription	8.547295e-3
GO:0016241	regulation of macroautophagy	8.556829e-3
GO:0010266	response to vitamin B1	8.639642e-3
GO:0031123	RNA 3'-end processing	8.639845e-3
GO:0014038	regulation of Schwann cell differentiation	8.776365e-3
GO:0070389	chaperone cofactor-dependent protein refolding	8.884673e-3
GO:0006613	cotranslational protein targeting to membrane	8.976325e-3
GO:0042093	T-helper cell differentiation	9.229442e-3
GO:0046069	cGMP catabolic process	9.353486e-3
GO:0045039	protein import into mitochondrial inner membrane	9.481826e-3
GO:0044088	regulation of vacuole organization	9.591088e-3
GO:0043624	cellular protein complex disassembly	9.740555e-3
GO:0060281	regulation of oocyte development	9.769915e-3
GO:0006311	meiotic gene conversion	9.980796e-3
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	9.980796e-3
GO:0045128	negative regulation of reciprocal meiotic recombination	9.980796e-3
GO:0009589	detection of UV	9.980796e-3
GO:0046329	negative regulation of JNK cascade	1.009120e-2
GO:0021707	cerebellar granule cell differentiation	1.029569e-2
GO:0010172	embryonic body morphogenesis	1.029569e-2
GO:0090381	regulation of heart induction	1.047987e-2
GO:0006670	sphingosine metabolic process	1.097654e-2
GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	1.097893e-2
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.116569e-2
GO:0051301	cell division	1.120277e-2
GO:0042726	flavin-containing compound metabolic process	1.125781e-2
GO:0034048	negative regulation of protein phosphatase type 2A activity	1.125781e-2
GO:0000375	RNA splicing, via transesterification reactions	1.145348e-2
GO:0043171	peptide catabolic process	1.161502e-2
GO:0072361	regulation of glycolysis by regulation of transcription from RNA polymerase II promoter	1.162048e-2
GO:0060431	primary lung bud formation	1.162048e-2
GO:0014040	positive regulation of Schwann cell differentiation	1.162048e-2
GO:0031440	regulation of mRNA 3'-end processing	1.182978e-2
GO:0032536	regulation of cell projection size	1.185162e-2
GO:0061153	trachea gland development	1.192349e-2
GO:0048103	somatic stem cell division	1.225592e-2
GO:0007051	spindle organization	1.230287e-2
GO:0048280	vesicle fusion with Golgi apparatus	1.234911e-2
GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint	1.251475e-2
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.259939e-2
GO:0031627	telomeric loop formation	1.260307e-2
GO:0071279	cellular response to cobalt ion	1.260307e-2
GO:0010637	negative regulation of mitochondrial fusion	1.260307e-2
GO:0006397	mRNA processing	1.263037e-2
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.271607e-2
GO:0060631	regulation of meiosis I	1.277999e-2
GO:0060301	positive regulation of cytokine activity	1.277999e-2
GO:0007130	synaptonemal complex assembly	1.305815e-2
GO:0045656	negative regulation of monocyte differentiation	1.309989e-2
GO:0008612	peptidyl-lysine modification to hypusine	1.314376e-2
GO:0000096	sulfur amino acid metabolic process	1.327624e-2
GO:0002293	alpha-beta T cell differentiation involved in immune response	1.330657e-2
GO:0046434	organophosphate catabolic process	1.342886e-2
GO:0008053	mitochondrial fusion	1.365636e-2
GO:0032928	regulation of superoxide anion generation	1.382823e-2
GO:0015910	peroxisomal long-chain fatty acid import	1.383054e-2
GO:0000492	box C/D snoRNP assembly	1.383054e-2
GO:0042274	ribosomal small subunit biogenesis	1.386608e-2
GO:0001732	formation of translation initiation complex	1.401817e-2
GO:0006302	double-strand break repair	1.416252e-2
GO:0071103	DNA conformation change	1.443791e-2
GO:0032543	mitochondrial translation	1.448763e-2
GO:0030262	apoptotic nuclear change	1.453405e-2
GO:0021542	dentate gyrus development	1.455672e-2
GO:2000077	negative regulation of type B pancreatic cell development	1.512315e-2
GO:0060070	canonical Wnt receptor signaling pathway	1.515719e-2
GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter	1.542686e-2
GO:0072363	regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter	1.542686e-2
GO:0060385	axonogenesis involved in innervation	1.558143e-2
GO:0046607	positive regulation of centrosome cycle	1.558143e-2
GO:0032042	mitochondrial DNA metabolic process	1.656416e-2
GO:0048262	determination of dorsal/ventral asymmetry	1.672762e-2
GO:0043457	regulation of cellular respiration	1.672762e-2
GO:0021535	cell migration in hindbrain	1.697233e-2
GO:0008634	negative regulation of survival gene product expression	1.697233e-2
GO:0033136	serine phosphorylation of STAT3 protein	1.714150e-2
GO:0006598	polyamine catabolic process	1.714150e-2
GO:0032613	interleukin-10 production	1.714150e-2
GO:2000602	regulation of interphase of mitotic cell cycle	1.716858e-2
GO:0016081	synaptic vesicle docking involved in exocytosis	1.725143e-2
GO:0070814	hydrogen sulfide biosynthetic process	1.733277e-2
GO:0046853	inositol or phosphatidylinositol phosphorylation	1.733277e-2
GO:0035110	leg morphogenesis	1.773802e-2
GO:0043241	protein complex disassembly	1.780815e-2
GO:0020028	hemoglobin import	1.783211e-2
GO:0070972	protein localization in endoplasmic reticulum	1.790089e-2
GO:0000279	M phase	1.797489e-2
GO:0045931	positive regulation of mitotic cell cycle	1.805295e-2
GO:0042218	1-aminocyclopropane-1-carboxylate biosynthetic process	1.822897e-2
GO:0070979	protein K11-linked ubiquitination	1.841574e-2
GO:0032897	negative regulation of viral transcription	1.887209e-2
GO:0097107	postsynaptic density assembly	1.892086e-2
GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	1.892086e-2
GO:0043990	histone H2A-S1 phosphorylation	1.892086e-2
GO:0034725	DNA replication-dependent nucleosome disassembly	1.892086e-2
GO:0033314	mitotic cell cycle DNA replication checkpoint	1.892086e-2
GO:0006862	nucleotide transport	1.903308e-2
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.920869e-2
GO:0043403	skeletal muscle tissue regeneration	1.946365e-2
GO:0021877	forebrain neuron fate commitment	1.964237e-2
GO:0043508	negative regulation of JUN kinase activity	1.970286e-2
GO:0060479	lung cell differentiation	1.974713e-2
GO:0071168	protein localization to chromatin	1.980564e-2
GO:0000398	nuclear mRNA splicing, via spliceosome	2.006208e-2
GO:0044272	sulfur compound biosynthetic process	2.018425e-2
GO:0050983	deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase	2.050112e-2
GO:0070309	lens fiber cell morphogenesis	2.050806e-2
GO:0006108	malate metabolic process	2.050806e-2
GO:0032661	regulation of interleukin-18 production	2.050806e-2
GO:0033145	positive regulation of steroid hormone receptor signaling pathway	2.051031e-2
GO:0051297	centrosome organization	2.059149e-2
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.073494e-2
GO:0016476	regulation of embryonic cell shape	2.093849e-2
GO:0003218	cardiac left ventricle formation	2.093849e-2
GO:0001842	neural fold formation	2.093849e-2
GO:0032481	positive regulation of type I interferon production	2.133639e-2
GO:0031507	heterochromatin formation	2.137616e-2
GO:0009886	post-embryonic morphogenesis	2.209577e-2
GO:0050684	regulation of mRNA processing	2.214500e-2
GO:0002200	somatic diversification of immune receptors	2.222298e-2
GO:0071864	positive regulation of cell proliferation in bone marrow	2.290031e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0006396	RNA processing	4.180959e-15
GO:0016071	mRNA metabolic process	1.728639e-13
GO:0060837	blood vessel endothelial cell differentiation	4.079679e-10
GO:0046069	cGMP catabolic process	4.124586e-10
GO:0006397	mRNA processing	6.920127e-10
GO:0021528	commissural neuron differentiation in spinal cord	9.343775e-9
GO:0008616	queuosine biosynthetic process	2.054624e-8
GO:0071157	negative regulation of cell cycle arrest	2.270189e-8
GO:0010467	gene expression	4.163725e-8
GO:0046666	retinal cell programmed cell death	7.142366e-8
GO:0055119	relaxation of cardiac muscle	1.060738e-7
GO:0008380	RNA splicing	1.095034e-7
GO:0030644	cellular chloride ion homeostasis	1.095986e-7
GO:0090304	nucleic acid metabolic process	1.252862e-7
GO:0018293	protein-FAD linkage	2.414679e-7
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	2.414679e-7
GO:0030320	cellular monovalent inorganic anion homeostasis	3.602553e-7
GO:0048050	post-embryonic eye morphogenesis	4.617090e-7
GO:0060236	regulation of mitotic spindle organization	6.274448e-7
GO:0016070	RNA metabolic process	6.582558e-7
GO:0060282	positive regulation of oocyte development	7.819163e-7
GO:0060281	regulation of oocyte development	7.819163e-7
GO:0008617	guanosine metabolic process	9.410148e-7
GO:0035234	germ cell programmed cell death	1.006019e-6
GO:0055118	negative regulation of cardiac muscle contraction	1.285188e-6
GO:0010564	regulation of cell cycle process	1.394409e-6
GO:0044260	cellular macromolecule metabolic process	1.461096e-6
GO:0010623	developmental programmed cell death	1.547616e-6
GO:0007049	cell cycle	1.636352e-6
GO:0046839	phospholipid dephosphorylation	2.632444e-6
GO:0009299	mRNA transcription	3.516953e-6
GO:0010948	negative regulation of cell cycle process	3.580166e-6
GO:0033088	negative regulation of immature T cell proliferation in thymus	3.899519e-6
GO:0015986	ATP synthesis coupled proton transport	4.065753e-6
GO:0010735	positive regulation of transcription via serum response element binding	5.174571e-6
GO:0048627	myoblast development	5.540810e-6
GO:2000016	negative regulation of determination of dorsal identity	6.790688e-6
GO:0010891	negative regulation of sequestering of triglyceride	7.229182e-6
GO:0046856	phosphatidylinositol dephosphorylation	7.229182e-6
GO:0060928	atrioventricular node cell development	1.014908e-5
GO:0060929	atrioventricular node cell fate commitment	1.014908e-5
GO:0003342	proepicardium development	1.014908e-5
GO:0003168	cardiac Purkinje fiber cell differentiation	1.014908e-5
GO:0006780	uroporphyrinogen III biosynthetic process	1.014908e-5
GO:0035584	calcium-mediated signaling using intracellular calcium source	1.051069e-5
GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway	1.053527e-5
GO:0007088	regulation of mitosis	1.086273e-5
GO:0006983	ER overload response	1.297211e-5
GO:0018195	peptidyl-arginine modification	1.304953e-5
GO:0007031	peroxisome organization	1.316285e-5
GO:0016557	peroxisome membrane biogenesis	1.323469e-5
GO:0018216	peptidyl-arginine methylation	1.369305e-5
GO:0034470	ncRNA processing	1.449589e-5
GO:0010765	positive regulation of sodium ion transport	1.686342e-5
GO:0007032	endosome organization	1.704315e-5
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	1.961163e-5
GO:0042789	mRNA transcription from RNA polymerase II promoter	2.037795e-5
GO:0002368	B cell cytokine production	2.138235e-5
GO:0048291	isotype switching to IgG isotypes	2.138235e-5
GO:0002678	positive regulation of chronic inflammatory response	2.192623e-5
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	2.196546e-5
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	2.209276e-5
GO:0046068	cGMP metabolic process	2.728823e-5
GO:0051586	positive regulation of dopamine uptake	2.815995e-5
GO:0042178	xenobiotic catabolic process	3.061594e-5
GO:0010889	regulation of sequestering of triglyceride	3.104297e-5
GO:0034660	ncRNA metabolic process	3.360247e-5
GO:0048668	collateral sprouting	3.470798e-5
GO:0035993	deltoid tuberosity development	3.470798e-5
GO:0006625	protein targeting to peroxisome	3.657391e-5
GO:0016082	synaptic vesicle priming	3.676174e-5
GO:0042773	ATP synthesis coupled electron transport	4.622957e-5
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	4.629919e-5
GO:0035246	peptidyl-arginine N-methylation	4.920979e-5
GO:0060440	trachea formation	4.923855e-5
GO:0051030	snRNA transport	5.018291e-5
GO:0045046	protein import into peroxisome membrane	5.474739e-5
GO:0010464	regulation of mesenchymal cell proliferation	5.706249e-5
GO:0002053	positive regulation of mesenchymal cell proliferation	6.119996e-5
GO:0032225	regulation of synaptic transmission, dopaminergic	6.122694e-5
GO:0032474	otolith morphogenesis	6.179623e-5
GO:0045143	homologous chromosome segregation	6.864038e-5
GO:0071539	protein localization to centrosome	7.453050e-5
GO:0033566	gamma-tubulin complex localization	7.453050e-5
GO:0072198	mesenchymal cell proliferation involved in ureter development	7.453315e-5
GO:0072192	ureter epithelial cell differentiation	7.453315e-5
GO:0072138	mesenchymal cell proliferation involved in ureteric bud development	7.453315e-5
GO:0072101	specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway	7.453315e-5
GO:2000005	negative regulation of metanephric S-shaped body morphogenesis	7.453315e-5
GO:2000137	negative regulation of cell proliferation involved in heart morphogenesis	7.453315e-5
GO:2000007	negative regulation of metanephric comma-shaped body morphogenesis	7.453315e-5
GO:0090194	negative regulation of glomerulus development	7.453315e-5
GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis	7.453315e-5
GO:0072200	negative regulation of mesenchymal cell proliferation involved in ureter development	7.453315e-5
GO:0060502	epithelial cell proliferation involved in lung morphogenesis	7.453315e-5
GO:0055020	positive regulation of cardiac muscle fiber development	7.453315e-5
GO:0072097	negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway	7.453315e-5
GO:0007500	mesodermal cell fate determination	7.453315e-5
GO:0060503	bud dilation involved in lung branching	7.453315e-5
GO:0048392	intermediate mesodermal cell differentiation	7.453315e-5
GO:0071893	BMP signaling pathway involved in nephric duct formation	7.453315e-5
GO:0061149	BMP signaling pathway involved in ureter morphogenesis	7.453315e-5
GO:0061155	pulmonary artery endothelial tube morphogenesis	7.453315e-5
GO:0061151	BMP signaling pathway involved in renal system segmentation	7.453315e-5
GO:0071044	histone mRNA catabolic process	7.685653e-5
GO:0060319	primitive erythrocyte differentiation	7.834053e-5
GO:0051645	Golgi localization	1.019557e-4
GO:0042026	protein refolding	1.167869e-4
GO:0071777	positive regulation of cell cycle cytokinesis	1.169463e-4
GO:0055005	ventricular cardiac myofibril development	1.226424e-4
GO:0060554	induction of necroptosis of activated-T cells	1.229161e-4
GO:0006713	glucocorticoid catabolic process	1.229161e-4
GO:0010224	response to UV-B	1.262877e-4
GO:0016081	synaptic vesicle docking involved in exocytosis	1.301071e-4
GO:0015969	guanosine tetraphosphate metabolic process	1.389154e-4
GO:0035990	tendon cell differentiation	1.509296e-4
GO:0060390	regulation of SMAD protein import into nucleus	1.578426e-4
GO:0006139	nucleobase-containing compound metabolic process	1.587852e-4
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	1.608843e-4
GO:0045839	negative regulation of mitosis	1.634552e-4
GO:0048597	post-embryonic camera-type eye morphogenesis	1.686908e-4
GO:0018022	peptidyl-lysine methylation	1.748308e-4
GO:0007052	mitotic spindle organization	1.748565e-4
GO:0001777	T cell homeostatic proliferation	1.921648e-4
GO:0032057	negative regulation of translational initiation in response to stress	1.921648e-4
GO:0072594	establishment of protein localization to organelle	2.062866e-4
GO:0018065	protein-cofactor linkage	2.072348e-4
GO:0002028	regulation of sodium ion transport	2.153817e-4
GO:0006412	translation	2.162856e-4
GO:0032353	negative regulation of hormone biosynthetic process	2.235230e-4
GO:0042775	mitochondrial ATP synthesis coupled electron transport	2.250007e-4
GO:0007292	female gamete generation	2.378334e-4
GO:0034776	response to histamine	2.676818e-4
GO:0019858	cytosine metabolic process	2.676818e-4
GO:0048388	endosomal lumen acidification	2.735011e-4
GO:0044091	membrane biogenesis	2.786928e-4
GO:0001880	Mullerian duct regression	2.786928e-4
GO:0009586	rhodopsin mediated phototransduction	2.786928e-4
GO:0030263	apoptotic chromosome condensation	2.788648e-4
GO:0060058	positive regulation of apoptosis involved in mammary gland involution	2.848545e-4
GO:0090271	positive regulation of fibroblast growth factor production	2.876020e-4
GO:0090336	positive regulation of brown fat cell differentiation	2.876020e-4
GO:0090362	positive regulation of platelet-derived growth factor production	2.876020e-4
GO:0070831	basement membrane assembly	2.876020e-4
GO:0008208	C21-steroid hormone catabolic process	2.876020e-4
GO:0016191	synaptic vesicle uncoating	2.876020e-4
GO:0060377	negative regulation of mast cell differentiation	2.876020e-4
GO:0060971	embryonic heart tube left/right pattern formation	2.876020e-4
GO:0006401	RNA catabolic process	3.076008e-4
GO:0048563	post-embryonic organ morphogenesis	3.138851e-4
GO:0009214	cyclic nucleotide catabolic process	3.247903e-4
GO:0001840	neural plate development	3.302381e-4
GO:0001839	neural plate morphogenesis	3.339864e-4
GO:0090224	regulation of spindle organization	3.485780e-4
GO:2000078	positive regulation of type B pancreatic cell development	3.685666e-4
GO:0015886	heme transport	3.685666e-4
GO:0061015	snRNA import into nucleus	3.736464e-4
GO:0017187	peptidyl-glutamic acid carboxylation	3.736464e-4
GO:0048213	Golgi vesicle prefusion complex stabilization	3.736464e-4
GO:0048813	dendrite morphogenesis	3.738672e-4
GO:0006471	protein ADP-ribosylation	3.834258e-4
GO:0060391	positive regulation of SMAD protein import into nucleus	4.078314e-4
GO:0060449	bud elongation involved in lung branching	4.078984e-4
GO:0010613	positive regulation of cardiac muscle hypertrophy	4.135015e-4
GO:0003278	apoptosis involved in heart morphogenesis	4.150843e-4
GO:0031047	gene silencing by RNA	4.200465e-4
GO:0001887	selenium compound metabolic process	4.251206e-4
GO:0060084	synaptic transmission involved in micturition	4.642549e-4
GO:0010933	positive regulation of macrophage tolerance induction	4.642549e-4
GO:0003130	BMP signaling pathway involved in heart induction	4.793263e-4
GO:0060413	atrial septum morphogenesis	4.831169e-4
GO:0006117	acetaldehyde metabolic process	5.226943e-4
GO:0051302	regulation of cell division	5.269963e-4
GO:0009886	post-embryonic morphogenesis	5.284116e-4
GO:0007090	regulation of S phase of mitotic cell cycle	5.284116e-4
GO:0050908	detection of light stimulus involved in visual perception	5.665199e-4
GO:0030219	megakaryocyte differentiation	5.795027e-4
GO:0019509	L-methionine salvage from methylthioadenosine	5.809486e-4
GO:0030002	cellular anion homeostasis	5.811892e-4
GO:0018023	peptidyl-lysine trimethylation	6.143605e-4
GO:0007614	short-term memory	6.241225e-4
GO:0009103	lipopolysaccharide biosynthetic process	6.738303e-4
GO:0006364	rRNA processing	6.934847e-4
GO:0003283	atrial septum development	7.204186e-4
GO:0051588	regulation of neurotransmitter transport	7.461649e-4
GO:0002331	pre-B cell allelic exclusion	7.708987e-4
GO:0070562	regulation of vitamin D receptor signaling pathway	7.771057e-4
GO:0033590	response to cobalamin	7.919550e-4
GO:0046502	uroporphyrinogen III metabolic process	7.919550e-4
GO:0016139	glycoside catabolic process	7.919550e-4
GO:0030264	nuclear fragmentation involved in apoptotic nuclear change	7.919550e-4
GO:0010216	maintenance of DNA methylation	8.423709e-4
GO:0051781	positive regulation of cell division	8.699580e-4
GO:0072285	mesenchymal to epithelial transition involved in metanephric renal vesicle formation	9.020424e-4
GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway	9.020424e-4
GO:0007371	ventral midline determination	9.020424e-4
GO:0060248	detection of cell density by contact stimulus involved in contact inhibition	9.020424e-4
GO:0018125	peptidyl-cysteine methylation	9.020424e-4
GO:0031947	negative regulation of glucocorticoid biosynthetic process	9.257115e-4
GO:0060433	bronchus development	9.380033e-4
GO:0006402	mRNA catabolic process	9.598737e-4
GO:0060046	regulation of acrosome reaction	1.047039e-3
GO:0071034	CUT catabolic process	1.055227e-3
GO:0030174	regulation of DNA-dependent DNA replication initiation	1.055227e-3
GO:0060684	epithelial-mesenchymal cell signaling	1.063599e-3
GO:0061046	regulation of branching involved in lung morphogenesis	1.097732e-3
GO:0051590	positive regulation of neurotransmitter transport	1.097732e-3
GO:0002320	lymphoid progenitor cell differentiation	1.125198e-3
GO:0000087	M phase of mitotic cell cycle	1.132009e-3
GO:0033692	cellular polysaccharide biosynthetic process	1.135704e-3
GO:0030071	regulation of mitotic metaphase/anaphase transition	1.159370e-3
GO:0072098	anterior/posterior pattern specification involved in kidney development	1.200495e-3
GO:0035441	cell migration involved in vasculogenesis	1.200495e-3
GO:0048389	intermediate mesoderm development	1.200495e-3
GO:0090307	spindle assembly involved in mitosis	1.308100e-3
GO:0008033	tRNA processing	1.328487e-3
GO:0042447	hormone catabolic process	1.339144e-3
GO:0051726	regulation of cell cycle	1.406624e-3
GO:0007603	phototransduction, visible light	1.430791e-3
GO:0022403	cell cycle phase	1.453929e-3
GO:0009125	nucleoside monophosphate catabolic process	1.457167e-3
GO:0006086	acetyl-CoA biosynthetic process from pyruvate	1.540546e-3
GO:0016072	rRNA metabolic process	1.564490e-3
GO:0070389	chaperone cofactor-dependent protein refolding	1.594690e-3
GO:0043248	proteasome assembly	1.594690e-3
GO:0071156	regulation of cell cycle arrest	1.617575e-3
GO:0006710	androgen catabolic process	1.632110e-3
GO:0060712	spongiotrophoblast layer development	1.635938e-3
GO:0051584	regulation of dopamine uptake	1.641955e-3
GO:0008334	histone mRNA metabolic process	1.646802e-3
GO:0022410	circadian sleep/wake cycle process	1.741912e-3
GO:0032298	positive regulation of DNA-dependent DNA replication initiation	1.742288e-3
GO:0002502	peptide antigen assembly with MHC class I protein complex	1.742288e-3
GO:0022904	respiratory electron transport chain	1.764147e-3
GO:0031570	DNA integrity checkpoint	1.780646e-3
GO:0061047	positive regulation of branching involved in lung morphogenesis	1.780854e-3
GO:0061154	endothelial tube morphogenesis	1.780854e-3
GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	1.780854e-3
GO:0010950	positive regulation of endopeptidase activity	1.803916e-3
GO:0000278	mitotic cell cycle	1.813611e-3
GO:0007094	mitotic cell cycle spindle assembly checkpoint	1.877013e-3
GO:0043170	macromolecule metabolic process	1.899927e-3
GO:0019369	arachidonic acid metabolic process	2.017693e-3
GO:0003158	endothelium development	2.080840e-3
GO:0070827	chromatin maintenance	2.107748e-3
GO:0035946	mitochondrial mRNA surveillance	2.107748e-3
GO:0035945	mitochondrial ncRNA surveillance	2.107748e-3
GO:0071174	mitotic cell cycle spindle checkpoint	2.137801e-3
GO:0043314	negative regulation of neutrophil degranulation	2.137801e-3
GO:0043461	proton-transporting ATP synthase complex assembly	2.140405e-3
GO:0042770	signal transduction in response to DNA damage	2.162493e-3
GO:0048070	regulation of developmental pigmentation	2.169099e-3
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	2.181720e-3
GO:0043060	meiotic metaphase I plate congression	2.234023e-3
GO:0002352	B cell negative selection	2.234023e-3
GO:0019371	cyclooxygenase pathway	2.234023e-3
GO:0071173	spindle assembly checkpoint	2.257616e-3
GO:0072560	type B pancreatic cell maturation	2.272085e-3
GO:0007023	post-chaperonin tubulin folding pathway	2.272085e-3
GO:0045947	negative regulation of translational initiation	2.327965e-3
GO:0035855	megakaryocyte development	2.426213e-3
GO:0060555	induction of necroptosis by extracellular signals	2.434252e-3
GO:0042130	negative regulation of T cell proliferation	2.438556e-3
GO:0042745	circadian sleep/wake cycle	2.459474e-3
GO:0043149	stress fiber assembly	2.462581e-3
GO:0045987	positive regulation of smooth muscle contraction	2.502985e-3
GO:0010888	negative regulation of lipid storage	2.503082e-3
GO:0060040	retinal bipolar neuron differentiation	2.552073e-3
GO:0007067	mitosis	2.572593e-3
GO:0045187	regulation of circadian sleep/wake cycle, sleep	2.702634e-3
GO:0043586	tongue development	2.741335e-3
GO:0071733	transcriptional activation by promoter-enhancer looping	2.782687e-3
GO:0000715	nucleotide-excision repair, DNA damage recognition	2.782687e-3
GO:0014040	positive regulation of Schwann cell differentiation	2.782687e-3
GO:0043525	positive regulation of neuron apoptosis	2.943294e-3
GO:0006298	mismatch repair	2.977634e-3
GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	3.020391e-3
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	3.029700e-3
GO:0022900	electron transport chain	3.048162e-3
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	3.065879e-3
GO:0043137	DNA replication, removal of RNA primer	3.065879e-3
GO:0006119	oxidative phosphorylation	3.074239e-3
GO:0070244	negative regulation of thymocyte apoptosis	3.093780e-3
GO:0010608	posttranscriptional regulation of gene expression	3.097460e-3
GO:0032446	protein modification by small protein conjugation	3.123119e-3
GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	3.224050e-3
GO:0000077	DNA damage checkpoint	3.264940e-3
GO:0042053	regulation of dopamine metabolic process	3.291264e-3
GO:0005978	glycogen biosynthetic process	3.315417e-3
GO:0050672	negative regulation of lymphocyte proliferation	3.346765e-3
GO:0033261	regulation of S phase	3.392008e-3
GO:0021904	dorsal/ventral neural tube patterning	3.409965e-3
GO:0003221	right ventricular cardiac muscle tissue morphogenesis	3.422510e-3
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	3.422510e-3
GO:0045933	positive regulation of muscle contraction	3.513223e-3
GO:0055025	positive regulation of cardiac muscle tissue development	3.549972e-3
GO:0051310	metaphase plate congression	3.599809e-3
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	3.609502e-3
GO:0048102	autophagic cell death	3.681499e-3
GO:0016567	protein ubiquitination	3.736362e-3
GO:0060215	primitive hemopoiesis	3.766283e-3
GO:0045988	negative regulation of striated muscle contraction	3.795771e-3
GO:2000112	regulation of cellular macromolecule biosynthetic process	3.964046e-3
GO:0070664	negative regulation of leukocyte proliferation	3.995634e-3
GO:0006435	threonyl-tRNA aminoacylation	4.029804e-3
GO:0008354	germ cell migration	4.104902e-3
GO:0046931	pore complex assembly	4.145487e-3
GO:0051204	protein insertion into mitochondrial membrane	4.145487e-3
GO:0022007	convergent extension involved in neural plate elongation	4.145487e-3
GO:0071267	L-methionine salvage	4.161496e-3
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	4.161496e-3
GO:0006925	inflammatory cell apoptosis	4.161496e-3
GO:2000344	positive regulation of acrosome reaction	4.189587e-3
GO:0014056	regulation of acetylcholine secretion	4.189587e-3
GO:0031577	spindle checkpoint	4.229995e-3
GO:0051580	regulation of neurotransmitter uptake	4.318884e-3
GO:0031062	positive regulation of histone methylation	4.318884e-3
GO:0048701	embryonic cranial skeleton morphogenesis	4.347524e-3
GO:0035582	negative regulation of BMP signaling pathway by extracellular sequestering of BMP	4.551100e-3
GO:0006285	base-excision repair, AP site formation	4.551100e-3
GO:0033084	regulation of immature T cell proliferation in thymus	4.660096e-3
GO:0090185	negative regulation of kidney development	4.811648e-3
GO:0045079	negative regulation of chemokine biosynthetic process	5.007594e-3
GO:0090072	positive regulation of sodium ion transport via voltage-gated sodium channel activity	5.007594e-3
GO:0006975	DNA damage induced protein phosphorylation	5.007594e-3
GO:0002358	B cell homeostatic proliferation	5.007594e-3
GO:0070585	protein localization in mitochondrion	5.019553e-3
GO:0051252	regulation of RNA metabolic process	5.066895e-3
GO:0017157	regulation of exocytosis	5.111532e-3
GO:0071480	cellular response to gamma radiation	5.123421e-3
GO:0006273	lagging strand elongation	5.179423e-3
GO:0072655	establishment of protein localization in mitochondrion	5.274139e-3
GO:0022402	cell cycle process	5.321618e-3
GO:0002031	G-protein coupled receptor internalization	5.362710e-3
GO:0034453	microtubule anchoring	5.379698e-3
GO:0043313	regulation of neutrophil degranulation	5.388950e-3
GO:0001541	ovarian follicle development	5.411445e-3
GO:0044237	cellular metabolic process	5.454348e-3
GO:0032330	regulation of chondrocyte differentiation	5.485591e-3
GO:0050883	musculoskeletal movement, spinal reflex action	5.553180e-3
GO:0042069	regulation of catecholamine metabolic process	5.583866e-3
GO:0007341	penetration of zona pellucida	5.583866e-3
GO:0019836	hemolysis by symbiont of host erythrocytes	5.621633e-3
GO:0016358	dendrite development	5.651293e-3
GO:0045880	positive regulation of smoothened signaling pathway	5.939441e-3
GO:0043558	regulation of translational initiation in response to stress	5.968639e-3
GO:0050774	negative regulation of dendrite morphogenesis	6.034013e-3
GO:0010940	positive regulation of necrotic cell death	6.034013e-3
GO:0048285	organelle fission	6.071342e-3
GO:0035356	cellular triglyceride homeostasis	6.129761e-3
GO:0010637	negative regulation of mitochondrial fusion	6.129761e-3
GO:0071279	cellular response to cobalt ion	6.129761e-3
GO:0000965	mitochondrial RNA 3'-end processing	6.129761e-3
GO:0000958	mitochondrial mRNA catabolic process	6.129761e-3
GO:0000962	positive regulation of mitochondrial RNA catabolic process	6.129761e-3
GO:0002221	pattern recognition receptor signaling pathway	6.147063e-3
GO:0009584	detection of visible light	6.256197e-3
GO:0000956	nuclear-transcribed mRNA catabolic process	6.272586e-3
GO:0051952	regulation of amine transport	6.346255e-3
GO:0046628	positive regulation of insulin receptor signaling pathway	6.372980e-3
GO:0071985	multivesicular body sorting pathway	6.529413e-3
GO:0070914	UV-damage excision repair	6.529413e-3
GO:0008582	regulation of synaptic growth at neuromuscular junction	6.529413e-3
GO:0016340	calcium-dependent cell-matrix adhesion	6.529413e-3
GO:0032465	regulation of cytokinesis	6.536702e-3
GO:0046885	regulation of hormone biosynthetic process	6.575816e-3
GO:0001964	startle response	6.589326e-3
GO:0070625	zymogen granule exocytosis	6.594523e-3
GO:0071025	RNA surveillance	6.594523e-3
GO:0044314	protein K27-linked ubiquitination	6.594523e-3
GO:0018214	protein carboxylation	6.594523e-3
GO:0048478	replication fork protection	6.594523e-3
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	6.603199e-3
GO:0008653	lipopolysaccharide metabolic process	6.603199e-3
GO:0033083	regulation of immature T cell proliferation	6.729468e-3
GO:0006399	tRNA metabolic process	6.732994e-3
GO:0051303	establishment of chromosome localization	6.736266e-3
GO:0060841	venous blood vessel development	6.745441e-3
GO:0031573	intra-S DNA damage checkpoint	6.766023e-3
GO:0000226	microtubule cytoskeleton organization	6.953910e-3
GO:0045132	meiotic chromosome segregation	6.985057e-3
GO:0061039	ovum-producing ovary development	7.137805e-3
GO:0048569	post-embryonic organ development	7.138346e-3
GO:0045773	positive regulation of axon extension	7.269213e-3
GO:0035372	protein localization to microtubule	7.281233e-3
GO:2000015	regulation of determination of dorsal identity	7.281233e-3
GO:0006283	transcription-coupled nucleotide-excision repair	7.281233e-3
GO:0000085	G2 phase of mitotic cell cycle	7.281233e-3
GO:0003350	pulmonary myocardium development	7.282780e-3
GO:0030728	ovulation	7.340406e-3
GO:0072205	metanephric collecting duct development	7.342514e-3
GO:0008625	induction of apoptosis via death domain receptors	7.342514e-3
GO:0042772	DNA damage response, signal transduction resulting in transcription	7.436660e-3
GO:0010468	regulation of gene expression	7.456933e-3
GO:0031572	G2/M transition DNA damage checkpoint	7.508894e-3
GO:0003222	ventricular trabecular myocardium morphogenesis	7.561908e-3
GO:0035524	proline transmembrane transport	7.561908e-3
GO:0060395	SMAD protein signal transduction	7.621090e-3
GO:0032467	positive regulation of cytokinesis	7.673895e-3
GO:0045938	positive regulation of circadian sleep/wake cycle, sleep	7.782454e-3
GO:0090184	positive regulation of kidney development	7.851685e-3
GO:0048842	positive regulation of axon extension involved in axon guidance	8.093466e-3
GO:0000189	MAPK import into nucleus	8.093466e-3
GO:0006355	regulation of transcription, DNA-dependent	8.159948e-3
GO:0048255	mRNA stabilization	8.183670e-3
GO:0051571	positive regulation of histone H3-K4 methylation	8.266073e-3
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	8.266073e-3
GO:0002651	positive regulation of tolerance induction to self antigen	8.266073e-3
GO:0007195	inhibition of adenylate cyclase activity by dopamine receptor signaling pathway	8.266073e-3
GO:0007131	reciprocal meiotic recombination	8.408862e-3
GO:0072190	ureter urothelium development	8.424835e-3
GO:0031077	post-embryonic camera-type eye development	8.469570e-3
GO:0007346	regulation of mitotic cell cycle	8.477998e-3
GO:0017158	regulation of calcium ion-dependent exocytosis	8.522401e-3
GO:0051954	positive regulation of amine transport	8.742524e-3
GO:0032494	response to peptidoglycan	8.888745e-3
GO:0050482	arachidonic acid secretion	8.966108e-3
GO:0061156	pulmonary artery morphogenesis	9.367030e-3
GO:0021578	hindbrain maturation	9.367030e-3
GO:0090329	regulation of DNA-dependent DNA replication	9.438969e-3
GO:0001570	vasculogenesis	9.476353e-3
GO:0055117	regulation of cardiac muscle contraction	9.503686e-3
GO:0090270	regulation of fibroblast growth factor production	9.617161e-3
GO:0090084	negative regulation of inclusion body assembly	9.617161e-3
GO:0001844	protein insertion into mitochondrial membrane involved in induction of apoptosis	9.617161e-3
GO:0072498	embryonic skeletal joint development	9.656037e-3
GO:0006627	protein processing involved in protein targeting to mitochondrion	9.884206e-3
GO:0003094	glomerular filtration	9.884206e-3
GO:0002575	basophil chemotaxis	9.884206e-3
GO:0006090	pyruvate metabolic process	9.923643e-3
GO:0030258	lipid modification	1.010989e-2
GO:0000279	M phase	1.032294e-2
GO:0071478	cellular response to radiation	1.035581e-2
GO:2000467	positive regulation of glycogen (starch) synthase activity	1.039275e-2
GO:0015824	proline transport	1.053757e-2
GO:0010159	specification of organ position	1.053757e-2
GO:0061312	BMP signaling pathway involved in heart development	1.055551e-2
GO:0042254	ribosome biogenesis	1.084598e-2
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	1.092089e-2
GO:0010556	regulation of macromolecule biosynthetic process	1.105924e-2
GO:0001885	endothelial cell development	1.107980e-2
GO:0060285	ciliary cell motility	1.111251e-2
GO:0035095	behavioral response to nicotine	1.111251e-2
GO:0006417	regulation of translation	1.124295e-2
GO:0060926	pacemaker cell development	1.144725e-2
GO:0060932	His-Purkinje system cell differentiation	1.144725e-2
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.144725e-2
GO:0031497	chromatin assembly	1.148719e-2
GO:0006984	ER-nucleus signaling pathway	1.157845e-2
GO:0021771	lateral geniculate nucleus development	1.188587e-2
GO:0032185	septin cytoskeleton organization	1.209077e-2
GO:0006281	DNA repair	1.212198e-2
GO:0002904	positive regulation of B cell apoptosis	1.251889e-2
GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	1.265325e-2
GO:0055014	atrial cardiac muscle cell development	1.275875e-2
GO:0038007	netrin-activated signaling pathway	1.275875e-2
GO:0032055	negative regulation of translation in response to stress	1.275875e-2
GO:0008585	female gonad development	1.275940e-2
GO:0015992	proton transport	1.287075e-2
GO:0002758	innate immune response-activating signal transduction	1.333192e-2
GO:0070936	protein K48-linked ubiquitination	1.344672e-2
GO:0006974	response to DNA damage stimulus	1.358719e-2
GO:0009435	NAD biosynthetic process	1.360596e-2
GO:0043923	positive regulation by host of viral transcription	1.372953e-2
GO:0043967	histone H4 acetylation	1.392852e-2
GO:0042048	olfactory behavior	1.419057e-2
GO:0019532	oxalate transport	1.419057e-2
GO:0035162	embryonic hemopoiesis	1.419119e-2
GO:0032350	regulation of hormone metabolic process	1.426189e-2
GO:0006818	hydrogen transport	1.449442e-2
GO:0060434	bronchus morphogenesis	1.456215e-2
GO:0046070	dGTP metabolic process	1.456215e-2
GO:0090287	regulation of cellular response to growth factor stimulus	1.466528e-2
GO:0010898	positive regulation of triglyceride catabolic process	1.467872e-2
GO:0010611	regulation of cardiac muscle hypertrophy	1.471988e-2
GO:0032227	negative regulation of synaptic transmission, dopaminergic	1.475578e-2
GO:0046717	acid secretion	1.485304e-2
GO:0007051	spindle organization	1.492961e-2
GO:0001886	endothelial cell morphogenesis	1.494718e-2
GO:0070997	neuron death	1.511240e-2
GO:0042220	response to cocaine	1.546477e-2
GO:0001975	response to amphetamine	1.549173e-2
GO:0035249	synaptic transmission, glutamatergic	1.555181e-2
GO:0072385	minus-end-directed organelle transport along microtubule	1.557699e-2
GO:0043148	mitotic spindle stabilization	1.557699e-2
GO:0006408	snRNA export from nucleus	1.557699e-2
GO:0048845	venous blood vessel morphogenesis	1.567595e-2
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	1.598399e-2
GO:0090030	regulation of steroid hormone biosynthetic process	1.599042e-2
GO:0070541	response to platinum ion	1.605600e-2
GO:0048814	regulation of dendrite morphogenesis	1.626435e-2
GO:0009082	branched chain family amino acid biosynthetic process	1.638135e-2
GO:0090361	regulation of platelet-derived growth factor production	1.652861e-2
GO:0021750	vestibular nucleus development	1.652861e-2
GO:0010936	negative regulation of macrophage cytokine production	1.652861e-2
GO:0021679	cerebellar molecular layer development	1.652861e-2
GO:0021590	cerebellum maturation	1.652861e-2
GO:0034441	plasma lipoprotein particle oxidation	1.672565e-2
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	1.672565e-2
GO:0002645	positive regulation of tolerance induction	1.683199e-2