Novel motif:61

name:	motif61_KAYMGMTN

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0048239	negative regulation of DNA recombination at telomere	4.943212e-11
GO:0007208	activation of phospholipase C activity by serotonin receptor signaling pathway	1.795117e-10
GO:0031848	protection from non-homologous end joining at telomere	2.867088e-10
GO:0042149	cellular response to glucose starvation	6.993073e-10
GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	2.299959e-9
GO:0035507	regulation of myosin-light-chain-phosphatase activity	3.827210e-9
GO:0010569	regulation of double-strand break repair via homologous recombination	8.604468e-9
GO:0031860	telomeric 3' overhang formation	2.542775e-8
GO:0000183	chromatin silencing at rDNA	3.318209e-8
GO:0016233	telomere capping	4.135236e-8
GO:0071243	cellular response to arsenic-containing substance	6.278633e-8
GO:0043666	regulation of phosphoprotein phosphatase activity	8.259883e-8
GO:0070857	regulation of bile acid biosynthetic process	1.458115e-7
GO:0003329	pancreatic PP cell fate commitment	6.521090e-7
GO:0003326	pancreatic A cell fate commitment	6.521090e-7
GO:0045750	positive regulation of S phase of mitotic cell cycle	1.256760e-6
GO:0046685	response to arsenic-containing substance	1.340972e-6
GO:0060414	aorta smooth muscle tissue morphogenesis	1.955997e-6
GO:0015780	nucleotide-sugar transport	2.464356e-6
GO:0006529	asparagine biosynthetic process	3.369564e-6
GO:0060580	ventral spinal cord interneuron fate determination	5.427855e-6
GO:0046984	regulation of hemoglobin biosynthetic process	5.427855e-6
GO:0003327	type B pancreatic cell fate commitment	5.427855e-6
GO:0046502	uroporphyrinogen III metabolic process	7.748355e-6
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	1.019787e-5
GO:0043973	histone H3-K4 acetylation	1.019787e-5
GO:0046985	positive regulation of hemoglobin biosynthetic process	1.019787e-5
GO:0032972	regulation of muscle filament sliding speed	1.019787e-5
GO:0042249	establishment of planar polarity of embryonic epithelium	1.127282e-5
GO:0006264	mitochondrial DNA replication	1.336623e-5
GO:0045329	carnitine biosynthetic process	1.621711e-5
GO:0071670	smooth muscle cell chemotaxis	1.767355e-5
GO:0060981	cell migration involved in coronary angiogenesis	1.767355e-5
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	1.767355e-5
GO:0009589	detection of UV	1.767355e-5
GO:0010310	regulation of hydrogen peroxide metabolic process	1.963171e-5
GO:0070858	negative regulation of bile acid biosynthetic process	2.039072e-5
GO:0006430	lysyl-tRNA aminoacylation	2.286810e-5
GO:0045199	maintenance of epithelial cell apical/basal polarity	2.734728e-5
GO:0031627	telomeric loop formation	3.130668e-5
GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process	3.364844e-5
GO:0051967	negative regulation of synaptic transmission, glutamatergic	4.130600e-5
GO:0007210	serotonin receptor signaling pathway	4.437885e-5
GO:0050957	equilibrioception	4.732133e-5
GO:0006635	fatty acid beta-oxidation	5.479415e-5
GO:0032042	mitochondrial DNA metabolic process	6.558921e-5
GO:2000779	regulation of double-strand break repair	7.187031e-5
GO:0008643	carbohydrate transport	7.501020e-5
GO:0060242	contact inhibition	8.045086e-5
GO:0048243	norepinephrine secretion	8.148010e-5
GO:0060465	pharynx development	8.308587e-5
GO:0051355	proprioception involved in equilibrioception	8.308587e-5
GO:0035522	monoubiquitinated histone H2A deubiquitination	8.308587e-5
GO:0000076	DNA replication checkpoint	8.968082e-5
GO:0006528	asparagine metabolic process	9.048384e-5
GO:0001973	adenosine receptor signaling pathway	9.818304e-5
GO:0035909	aorta morphogenesis	9.919683e-5
GO:0043456	regulation of pentose-phosphate shunt	1.187538e-4
GO:0034447	very-low-density lipoprotein particle clearance	1.210677e-4
GO:0033034	positive regulation of myeloid cell apoptosis	1.255442e-4
GO:0043128	positive regulation of 1-phosphatidylinositol 4-kinase activity	1.487275e-4
GO:0006260	DNA replication	1.547895e-4
GO:0002882	positive regulation of chronic inflammatory response to non-antigenic stimulus	1.643567e-4
GO:0007004	telomere maintenance via telomerase	1.783558e-4
GO:0006348	chromatin silencing at telomere	1.869815e-4
GO:0035090	maintenance of apical/basal cell polarity	1.938283e-4
GO:0051181	cofactor transport	1.971681e-4
GO:0006541	glutamine metabolic process	2.179700e-4
GO:2000481	positive regulation of cAMP-dependent protein kinase activity	2.425237e-4
GO:2000534	positive regulation of renal albumin absorption	2.425237e-4
GO:0015742	alpha-ketoglutarate transport	2.425237e-4
GO:2000478	positive regulation of metanephric glomerular visceral epithelial cell development	2.425237e-4
GO:2000461	negative regulation of eukaryotic cell surface binding	2.425237e-4
GO:0070994	detection of oxidative stress	2.425237e-4
GO:0045714	regulation of low-density lipoprotein particle receptor biosynthetic process	2.436449e-4
GO:0015891	siderophore transport	2.560237e-4
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	2.627478e-4
GO:0071544	diphosphoinositol polyphosphate catabolic process	2.691304e-4
GO:0044205	'de novo' UMP biosynthetic process	2.780556e-4
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	3.299873e-4
GO:0007021	tubulin complex assembly	3.310464e-4
GO:0048665	neuron fate specification	3.450996e-4
GO:0071108	protein K48-linked deubiquitination	3.642410e-4
GO:0009107	lipoate biosynthetic process	3.731547e-4
GO:0001830	trophectodermal cell fate commitment	3.731547e-4
GO:0006901	vesicle coating	3.789938e-4
GO:0071385	cellular response to glucocorticoid stimulus	3.926502e-4
GO:0042254	ribosome biogenesis	4.051367e-4
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	4.126423e-4
GO:0018009	N-terminal peptidyl-L-cysteine N-palmitoylation	4.177703e-4
GO:0002679	respiratory burst involved in defense response	4.596319e-4
GO:0070253	somatostatin secretion	5.073690e-4
GO:0032812	positive regulation of epinephrine secretion	5.073690e-4
GO:0044342	type B pancreatic cell proliferation	5.086520e-4
GO:0010918	positive regulation of mitochondrial membrane potential	5.086520e-4
GO:0050775	positive regulation of dendrite morphogenesis	5.665747e-4
GO:0030072	peptide hormone secretion	5.922403e-4
GO:0043308	eosinophil degranulation	6.121634e-4
GO:0051089	constitutive protein ectodomain proteolysis	6.121634e-4
GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis	6.208318e-4
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	6.297435e-4
GO:0035329	hippo signaling cascade	6.478902e-4
GO:0014812	muscle cell migration	6.677581e-4
GO:0072272	proximal/distal pattern formation involved in metanephric nephron development	6.795208e-4
GO:0010727	negative regulation of hydrogen peroxide metabolic process	6.795208e-4
GO:0048013	ephrin receptor signaling pathway	6.825635e-4
GO:0060023	soft palate development	6.890929e-4
GO:0021517	ventral spinal cord development	6.906382e-4
GO:0000387	spliceosomal snRNP assembly	7.007467e-4
GO:0021513	spinal cord dorsal/ventral patterning	7.183523e-4
GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	7.775245e-4
GO:0060298	positive regulation of sarcomere organization	7.775245e-4
GO:0072668	tubulin complex biogenesis	7.832955e-4
GO:2000573	positive regulation of DNA biosynthetic process	7.848337e-4
GO:0042572	retinol metabolic process	8.099072e-4
GO:0018202	peptidyl-histidine modification	8.218867e-4
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	8.279769e-4
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	8.421444e-4
GO:0010871	negative regulation of receptor biosynthetic process	8.472322e-4
GO:0048484	enteric nervous system development	9.112244e-4
GO:0006900	membrane budding	9.513067e-4
GO:0060263	regulation of respiratory burst	9.599347e-4
GO:0006386	termination of RNA polymerase III transcription	9.735637e-4
GO:0006385	transcription elongation from RNA polymerase III promoter	9.735637e-4
GO:0071316	cellular response to nicotine	9.860035e-4
GO:0060297	regulation of sarcomere organization	9.886213e-4
GO:0032677	regulation of interleukin-8 production	9.907246e-4
GO:0071545	inositol phosphate catabolic process	9.941904e-4
GO:0009744	response to sucrose stimulus	1.018783e-3
GO:0010656	negative regulation of muscle cell apoptosis	1.029476e-3
GO:0006777	Mo-molybdopterin cofactor biosynthetic process	1.041685e-3
GO:0006278	RNA-dependent DNA replication	1.052226e-3
GO:0001659	temperature homeostasis	1.066175e-3
GO:0021511	spinal cord patterning	1.109197e-3
GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine	1.142356e-3
GO:0046333	octopamine metabolic process	1.151238e-3
GO:0042309	homoiothermy	1.151238e-3
GO:0072592	oxygen metabolic process	1.203924e-3
GO:0015874	norepinephrine transport	1.203924e-3
GO:0002536	respiratory burst involved in inflammatory response	1.236471e-3
GO:0000712	resolution of meiotic recombination intermediates	1.238879e-3
GO:0042424	catecholamine catabolic process	1.255678e-3
GO:0007029	endoplasmic reticulum organization	1.267950e-3
GO:0007200	activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger	1.336983e-3
GO:0046813	virion attachment, binding of host cell surface receptor	1.337482e-3
GO:0051450	myoblast proliferation	1.355721e-3
GO:0010811	positive regulation of cell-substrate adhesion	1.358292e-3
GO:0006261	DNA-dependent DNA replication	1.362435e-3
GO:0045629	negative regulation of T-helper 2 cell differentiation	1.362562e-3
GO:0008628	induction of apoptosis by hormones	1.364568e-3
GO:0043048	dolichyl monophosphate biosynthetic process	1.394016e-3
GO:0070986	left/right axis specification	1.425368e-3
GO:0043084	penile erection	1.497606e-3
GO:0019062	virion attachment to host cell surface receptor	1.538196e-3
GO:0015886	heme transport	1.540408e-3
GO:0001675	acrosome assembly	1.562654e-3
GO:0016198	axon choice point recognition	1.624449e-3
GO:2000162	negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis	1.673759e-3
GO:2000164	negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis	1.673759e-3
GO:2000166	negative regulation of planar cell polarity pathway involved in pericardium morphogenesis	1.673759e-3
GO:2000168	negative regulation of planar cell polarity pathway involved in neural tube closure	1.673759e-3
GO:2000149	negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis	1.673759e-3
GO:2000151	negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	1.673759e-3
GO:0061310	canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development	1.673759e-3
GO:0002071	glandular epithelial cell maturation	1.673759e-3
GO:2000055	positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	1.673759e-3
GO:0046619	optic placode formation involved in camera-type eye formation	1.677928e-3
GO:0002098	tRNA wobble uridine modification	1.677928e-3
GO:0034227	tRNA thio-modification	1.677928e-3
GO:0021530	spinal cord oligodendrocyte cell fate specification	1.763738e-3
GO:0030011	maintenance of cell polarity	1.773606e-3
GO:0046511	sphinganine biosynthetic process	1.839795e-3
GO:0016601	Rac protein signal transduction	1.949432e-3
GO:0006779	porphyrin-containing compound biosynthetic process	1.985664e-3
GO:0006422	aspartyl-tRNA aminoacylation	2.026621e-3
GO:0031427	response to methotrexate	2.026621e-3
GO:0048149	behavioral response to ethanol	2.058069e-3
GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	2.096678e-3
GO:0002790	peptide secretion	2.146658e-3
GO:0090245	axis elongation involved in somitogenesis	2.214592e-3
GO:0021874	Wnt receptor signaling pathway involved in forebrain neuroblast division	2.214592e-3
GO:0050884	neuromuscular process controlling posture	2.225449e-3
GO:0097039	protein linear polyubiquitination	2.288388e-3
GO:0000244	assembly of spliceosomal tri-snRNP	2.329256e-3
GO:0042558	pteridine-containing compound metabolic process	2.528702e-3
GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	2.535846e-3
GO:0045910	negative regulation of DNA recombination	2.542923e-3
GO:0060266	negative regulation of respiratory burst involved in inflammatory response	2.570792e-3
GO:0048016	inositol phosphate-mediated signaling	2.577267e-3
GO:0042321	negative regulation of circadian sleep/wake cycle, sleep	2.599603e-3
GO:0001824	blastocyst development	2.667665e-3
GO:0048677	axon extension involved in regeneration	2.817936e-3
GO:0072274	metanephric glomerular basement membrane development	2.817936e-3
GO:0072249	metanephric glomerular visceral epithelial cell development	2.817936e-3
GO:0002721	regulation of B cell cytokine production	2.817936e-3
GO:0015761	mannose transport	2.817936e-3
GO:0018192	enzyme active site formation via L-cysteine persulfide	2.817936e-3
GO:0055009	atrial cardiac muscle tissue morphogenesis	2.844280e-3
GO:0018095	protein polyglutamylation	2.860418e-3
GO:0044335	canonical Wnt receptor signaling pathway involved in neural crest cell differentiation	2.872248e-3
GO:0006448	regulation of translational elongation	2.967979e-3
GO:0035303	regulation of dephosphorylation	2.992943e-3
GO:0050748	negative regulation of lipoprotein metabolic process	3.114970e-3
GO:0090192	regulation of glomerulus development	3.142180e-3
GO:0051282	regulation of sequestering of calcium ion	3.162437e-3
GO:0022613	ribonucleoprotein complex biogenesis	3.254613e-3
GO:0050774	negative regulation of dendrite morphogenesis	3.364831e-3
GO:0060579	ventral spinal cord interneuron fate commitment	3.575416e-3
GO:0060264	regulation of respiratory burst involved in inflammatory response	3.846183e-3
GO:0034625	fatty acid elongation, monounsaturated fatty acid	3.853088e-3
GO:0008054	cyclin catabolic process	3.856032e-3
GO:0033211	adiponectin-mediated signaling pathway	3.874869e-3
GO:0046622	positive regulation of organ growth	3.932031e-3
GO:0072268	pattern specification involved in metanephros development	3.934235e-3
GO:0030910	olfactory placode formation	3.957608e-3
GO:0031468	nuclear envelope reassembly	4.162755e-3
GO:0051791	medium-chain fatty acid metabolic process	4.162755e-3
GO:0016561	protein import into peroxisome matrix, translocation	4.162755e-3
GO:0006542	glutamine biosynthetic process	4.300139e-3
GO:0045103	intermediate filament-based process	4.434248e-3
GO:0015833	peptide transport	4.528371e-3
GO:0019348	dolichol metabolic process	4.573745e-3
GO:0006463	steroid hormone receptor complex assembly	4.581199e-3
GO:0019068	virion assembly	4.732549e-3
GO:0051793	medium-chain fatty acid catabolic process	4.732549e-3
GO:0072262	metanephric glomerular mesangial cell proliferation involved in metanephros development	4.890054e-3
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	4.890054e-3
GO:0035461	vitamin transmembrane transport	4.890054e-3
GO:0001736	establishment of planar polarity	5.133968e-3
GO:0045414	regulation of interleukin-8 biosynthetic process	5.181415e-3
GO:0060214	endocardium formation	5.188256e-3
GO:0000117	regulation of transcription involved in G2/M-phase of mitotic cell cycle	5.188256e-3
GO:0046498	S-adenosylhomocysteine metabolic process	5.242064e-3
GO:0006778	porphyrin-containing compound metabolic process	5.249030e-3
GO:0051081	nuclear envelope disassembly	5.288556e-3
GO:0009437	carnitine metabolic process	5.644697e-3
GO:0003310	pancreatic A cell differentiation	5.644697e-3
GO:0070194	synaptonemal complex disassembly	5.679761e-3
GO:0060133	somatotropin secreting cell development	5.679761e-3
GO:0090251	protein localization involved in establishment of planar polarity	5.679761e-3
GO:0002431	Fc receptor mediated stimulatory signaling pathway	5.679761e-3
GO:0031662	positive regulation of cyclin-dependent protein kinase activity involved in G2/M	5.679761e-3
GO:0001805	positive regulation of type III hypersensitivity	5.679761e-3
GO:0015961	diadenosine polyphosphate catabolic process	5.679761e-3
GO:0045218	zonula adherens maintenance	5.683515e-3
GO:0009186	deoxyribonucleoside diphosphate metabolic process	5.683515e-3
GO:0051464	positive regulation of cortisol secretion	5.789502e-3
GO:0051725	protein de-ADP-ribosylation	5.789502e-3
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	5.789502e-3
GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep	5.789502e-3
GO:0033133	positive regulation of glucokinase activity	5.878533e-3
GO:0030382	sperm mitochondrion organization	5.878533e-3
GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	6.357355e-3
GO:0046339	diacylglycerol metabolic process	6.376657e-3
GO:0016553	base conversion or substitution editing	6.785169e-3
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	6.803777e-3
GO:0006668	sphinganine-1-phosphate metabolic process	6.803777e-3
GO:0006548	histidine catabolic process	6.823725e-3
GO:0060669	embryonic placenta morphogenesis	6.971478e-3
GO:0009062	fatty acid catabolic process	6.981782e-3
GO:0010921	regulation of phosphatase activity	7.058288e-3
GO:0032938	negative regulation of translation in response to oxidative stress	7.267656e-3
GO:0048291	isotype switching to IgG isotypes	7.267656e-3
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	7.267656e-3
GO:0002368	B cell cytokine production	7.267656e-3
GO:0050668	positive regulation of homocysteine metabolic process	7.284914e-3
GO:0061144	alveolar secondary septum development	7.284914e-3
GO:0045963	negative regulation of dopamine metabolic process	7.284914e-3
GO:0016598	protein arginylation	7.284914e-3
GO:0015878	biotin transport	7.284914e-3
GO:0015887	pantothenate transmembrane transport	7.284914e-3
GO:0033314	mitotic cell cycle DNA replication checkpoint	7.284914e-3
GO:0008645	hexose transport	7.350252e-3
GO:0006667	sphinganine metabolic process	7.437516e-3
GO:0046931	pore complex assembly	7.455813e-3
GO:0015749	monosaccharide transport	7.842100e-3
GO:0007623	circadian rhythm	7.924172e-3
GO:0042168	heme metabolic process	7.930854e-3
GO:0051462	regulation of cortisol secretion	7.937444e-3
GO:0032765	positive regulation of mast cell cytokine production	7.937444e-3
GO:0072134	nephrogenic mesenchyme morphogenesis	7.940707e-3
GO:0072015	glomerular visceral epithelial cell development	7.940707e-3
GO:0046718	entry of virus into host cell	7.984104e-3
GO:0034392	negative regulation of smooth muscle cell apoptosis	7.993585e-3
GO:0043584	nose development	8.116009e-3
GO:0008105	asymmetric protein localization	8.227007e-3
GO:0061003	positive regulation of dendritic spine morphogenesis	8.246753e-3
GO:0001743	optic placode formation	8.324645e-3
GO:0022616	DNA strand elongation	8.451434e-3
GO:0015876	acetyl-CoA transport	8.506080e-3
GO:0000027	ribosomal large subunit assembly	8.506080e-3
GO:0045576	mast cell activation	8.536914e-3
GO:0043266	regulation of potassium ion transport	8.598000e-3
GO:0006783	heme biosynthetic process	8.959621e-3
GO:0006651	diacylglycerol biosynthetic process	9.006184e-3
GO:0015959	diadenosine polyphosphate metabolic process	9.006184e-3
GO:0042273	ribosomal large subunit biogenesis	9.006883e-3
GO:0072329	monocarboxylic acid catabolic process	9.128895e-3
GO:0009106	lipoate metabolic process	9.208011e-3
GO:0032205	negative regulation of telomere maintenance	9.225188e-3
GO:0060384	innervation	9.269108e-3
GO:0006489	dolichyl diphosphate biosynthetic process	9.301062e-3
GO:0048199	vesicle targeting, to, from or within Golgi	9.330780e-3
GO:0006661	phosphatidylinositol biosynthetic process	9.438734e-3
GO:0048755	branching morphogenesis of a nerve	9.443883e-3
GO:0060449	bud elongation involved in lung branching	9.483627e-3
GO:0060662	salivary gland cavitation	9.865912e-3
GO:0033278	cell proliferation in midbrain	1.001239e-2
GO:0010994	free ubiquitin chain polymerization	1.001239e-2
GO:0048265	response to pain	1.014409e-2
GO:0071894	histone H2B conserved C-terminal lysine ubiquitination	1.017658e-2
GO:0051088	PMA-inducible membrane protein ectodomain proteolysis	1.017658e-2
GO:0045064	T-helper 2 cell differentiation	1.017658e-2
GO:0002315	marginal zone B cell differentiation	1.017658e-2
GO:0033013	tetrapyrrole metabolic process	1.039457e-2
GO:0090042	tubulin deacetylation	1.046451e-2
GO:0070846	Hsp90 deacetylation	1.046451e-2
GO:0051182	coenzyme transport	1.061326e-2
GO:0007164	establishment of tissue polarity	1.071985e-2
GO:0050433	regulation of catecholamine secretion	1.090883e-2
GO:0032873	negative regulation of stress-activated MAPK cascade	1.119049e-2
GO:0019233	sensory perception of pain	1.122703e-2
GO:0072193	ureter smooth muscle cell differentiation	1.146256e-2
GO:0034346	positive regulation of type III interferon production	1.146256e-2
GO:0090219	negative regulation of lipid kinase activity	1.164792e-2
GO:0007443	Malpighian tubule morphogenesis	1.164792e-2
GO:0000917	barrier septum formation	1.164792e-2
GO:0001834	trophectodermal cell proliferation	1.185274e-2
GO:0060686	negative regulation of prostatic bud formation	1.192110e-2
GO:0042752	regulation of circadian rhythm	1.192945e-2
GO:0061004	pattern specification involved in kidney development	1.199916e-2
GO:0050690	regulation of defense response to virus by virus	1.202575e-2
GO:0072110	glomerular mesangial cell proliferation	1.206091e-2
GO:0045986	negative regulation of smooth muscle contraction	1.206091e-2
GO:0043045	DNA methylation involved in embryo development	1.206091e-2
GO:0000413	protein peptidyl-prolyl isomerization	1.211093e-2
GO:0050965	detection of temperature stimulus involved in sensory perception of pain	1.216383e-2
GO:0021510	spinal cord development	1.261875e-2
GO:0051590	positive regulation of neurotransmitter transport	1.268824e-2
GO:0060659	nipple sheath formation	1.284302e-2
GO:0060649	mammary gland bud elongation	1.284302e-2
GO:0032099	negative regulation of appetite	1.294138e-2
GO:0016556	mRNA modification	1.294138e-2
GO:0001829	trophectodermal cell differentiation	1.306764e-2
GO:0001835	blastocyst hatching	1.319167e-2
GO:0006342	chromatin silencing	1.335323e-2
GO:0060560	developmental growth involved in morphogenesis	1.338118e-2
GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	1.390977e-2
GO:0010980	positive regulation of vitamin D 24-hydroxylase activity	1.390977e-2
GO:0007192	activation of adenylate cyclase activity by serotonin receptor signaling pathway	1.390977e-2
GO:0051764	actin crosslink formation	1.393862e-2
GO:0072104	glomerular capillary formation	1.432413e-2
GO:0000398	nuclear mRNA splicing, via spliceosome	1.433647e-2
GO:0070093	negative regulation of glucagon secretion	1.434316e-2
GO:0050666	regulation of homocysteine metabolic process	1.434316e-2
GO:0060087	relaxation of vascular smooth muscle	1.434918e-2
GO:0010739	positive regulation of protein kinase A signaling cascade	1.442063e-2
GO:0060670	branching involved in embryonic placenta morphogenesis	1.483956e-2
GO:0006482	protein demethylation	1.485383e-2
GO:0046434	organophosphate catabolic process	1.493570e-2
GO:0007195	inhibition of adenylate cyclase activity by dopamine receptor signaling pathway	1.499275e-2
GO:0071375	cellular response to peptide hormone stimulus	1.499354e-2
GO:0051209	release of sequestered calcium ion into cytosol	1.529276e-2
GO:0050975	sensory perception of touch	1.539492e-2
GO:0006382	adenosine to inosine editing	1.539492e-2
GO:0032757	positive regulation of interleukin-8 production	1.539606e-2
GO:0071539	protein localization to centrosome	1.572923e-2
GO:0072086	specification of loop of Henle identity	1.597717e-2
GO:0016525	negative regulation of angiogenesis	1.601348e-2
GO:0032910	regulation of transforming growth factor beta3 production	1.614518e-2
GO:0060695	negative regulation of cholesterol transporter activity	1.619362e-2
GO:0001812	positive regulation of type I hypersensitivity	1.619362e-2
GO:0033032	regulation of myeloid cell apoptosis	1.619920e-2
GO:0060596	mammary placode formation	1.636080e-2
GO:0046601	positive regulation of centriole replication	1.640000e-2
GO:0045356	positive regulation of interferon-alpha biosynthetic process	1.672866e-2
GO:0030260	entry into host cell	1.685063e-2
GO:0002149	hypochlorous acid biosynthetic process	1.689957e-2
GO:0019730	antimicrobial humoral response	1.705552e-2
GO:0042312	regulation of vasodilation	1.717287e-2
GO:0051660	establishment of centrosome localization	1.740207e-2
GO:0021540	corpus callosum morphogenesis	1.740207e-2
GO:0045354	regulation of interferon-alpha biosynthetic process	1.746575e-2
GO:0015884	folic acid transport	1.746575e-2
GO:0014821	phasic smooth muscle contraction	1.747032e-2
GO:0015758	glucose transport	1.747349e-2
GO:0072133	metanephric mesenchyme morphogenesis	1.773175e-2
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	1.775750e-2
GO:0070198	protein localization to chromosome, telomeric region	1.812292e-2
GO:0009263	deoxyribonucleotide biosynthetic process	1.812292e-2
GO:0010225	response to UV-C	1.812292e-2
GO:0010869	regulation of receptor biosynthetic process	1.838689e-2
GO:0032096	negative regulation of response to food	1.851535e-2
GO:0043537	negative regulation of blood vessel endothelial cell migration	1.857658e-2
GO:0043267	negative regulation of potassium ion transport	1.862577e-2
GO:0000375	RNA splicing, via transesterification reactions	1.865033e-2
GO:0071415	cellular response to purine-containing compound	1.871363e-2
GO:0051013	microtubule severing	1.871363e-2
GO:0035810	positive regulation of urine volume	1.880576e-2
GO:0071217	cellular response to external biotic stimulus	1.894755e-2
GO:0072111	cell proliferation involved in kidney development	1.898594e-2
GO:0071843	cellular component biogenesis at cellular level	1.902588e-2
GO:0009119	ribonucleoside metabolic process	1.905278e-2
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB cascade	1.911995e-2
GO:0019368	fatty acid elongation, unsaturated fatty acid	2.005252e-2
GO:0046499	S-adenosylmethioninamine metabolic process	2.022101e-2
GO:0031987	locomotion involved in locomotory behavior	2.022101e-2
GO:0009060	aerobic respiration	2.024472e-2
GO:0010976	positive regulation of neuron projection development	2.044909e-2
GO:0000956	nuclear-transcribed mRNA catabolic process	2.076401e-2
GO:0034384	high-density lipoprotein particle clearance	2.078971e-2
GO:0035883	enteroendocrine cell differentiation	2.083756e-2
GO:0032597	B cell receptor transport into membrane raft	2.083756e-2
GO:0033345	asparagine catabolic process via L-aspartate	2.083756e-2
GO:0032913	negative regulation of transforming growth factor beta3 production	2.083756e-2
GO:0032600	chemokine receptor transport out of membrane raft	2.083756e-2
GO:0042117	monocyte activation	2.087703e-2
GO:0016090	prenol metabolic process	2.118240e-2
GO:0021522	spinal cord motor neuron differentiation	2.142423e-2
GO:0072195	kidney smooth muscle cell differentiation	2.147835e-2
GO:0072105	ureteric peristalsis	2.147835e-2
GO:0006498	N-terminal protein lipidation	2.147835e-2
GO:0001738	morphogenesis of a polarized epithelium	2.157635e-2
GO:0045905	positive regulation of translational termination	2.163879e-2
GO:0045901	positive regulation of translational elongation	2.163879e-2
GO:0006452	translational frameshifting	2.163879e-2
GO:0019067	viral assembly, maturation, egress, and release	2.168553e-2
GO:0072203	cell proliferation involved in metanephros development	2.199607e-2
GO:0051382	kinetochore assembly	2.204461e-2
GO:0051567	histone H3-K9 methylation	2.204461e-2
GO:0034470	ncRNA processing	2.229235e-2
GO:0021514	ventral spinal cord interneuron differentiation	2.230252e-2
GO:0019230	proprioception	2.233629e-2
GO:0060648	mammary gland bud morphogenesis	2.241305e-2
GO:0003157	endocardium development	2.261695e-2
GO:0010388	cullin deneddylation	2.309908e-2
GO:0035088	establishment or maintenance of apical/basal cell polarity	2.310094e-2
GO:0035928	rRNA import into mitochondrion	2.341172e-2
GO:0006369	termination of RNA polymerase II transcription	2.385467e-2
GO:0072136	metanephric mesenchymal cell proliferation involved in metanephros development	2.398115e-2
GO:0015781	pyrimidine nucleotide-sugar transport	2.398115e-2
GO:0006207	'de novo' pyrimidine base biosynthetic process	2.402922e-2
GO:0035247	peptidyl-arginine omega-N-methylation	2.402922e-2
GO:0045931	positive regulation of mitotic cell cycle	2.409326e-2
GO:0042255	ribosome assembly	2.415837e-2
GO:0021535	cell migration in hindbrain	2.424325e-2
GO:2000296	negative regulation of hydrogen peroxide catabolic process	2.425992e-2
GO:0033342	negative regulation of collagen binding	2.425992e-2
GO:0045730	respiratory burst	2.439385e-2
GO:0060489	planar dichotomous subdivision of terminal units involved in lung branching morphogenesis	2.449543e-2
GO:0060700	regulation of ribonuclease activity	2.449543e-2
GO:0060490	lateral sprouting involved in lung morphogenesis	2.449543e-2
GO:0060488	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis	2.449543e-2
GO:0048105	establishment of body hair planar orientation	2.449543e-2
GO:0046329	negative regulation of JNK cascade	2.464559e-2
GO:0051257	spindle midzone assembly involved in meiosis	2.466015e-2
GO:0007060	male meiosis chromosome segregation	2.466015e-2
GO:0035441	cell migration involved in vasculogenesis	2.489816e-2
GO:0034442	regulation of lipoprotein oxidation	2.489816e-2
GO:0002069	columnar/cuboidal epithelial cell maturation	2.489816e-2
GO:0046128	purine ribonucleoside metabolic process	2.490372e-2
GO:0030819	positive regulation of cAMP biosynthetic process	2.496051e-2
GO:0010664	negative regulation of striated muscle cell apoptosis	2.503590e-2
GO:0072125	negative regulation of glomerular mesangial cell proliferation	2.523361e-2
GO:0072109	glomerular mesangium development	2.523361e-2
GO:0060572	morphogenesis of an epithelial bud	2.524514e-2
GO:0060155	platelet dense granule organization	2.529682e-2
GO:0046500	S-adenosylmethionine metabolic process	2.530536e-2
GO:0048935	peripheral nervous system neuron development	2.568676e-2
GO:0032780	negative regulation of ATPase activity	2.572762e-2
GO:0045176	apical protein localization	2.573634e-2
GO:0006364	rRNA processing	2.581434e-2
GO:0016575	histone deacetylation	2.602618e-2
GO:0072081	specification of nephron tubule identity	2.603375e-2
GO:0014909	smooth muscle cell migration	2.603375e-2
GO:0021986	habenula development	2.603375e-2
GO:0030073	insulin secretion	2.631902e-2
GO:0001984	vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure	2.635443e-2
GO:0001954	positive regulation of cell-matrix adhesion	2.639852e-2
GO:0071312	cellular response to alkaloid	2.668718e-2
GO:0045638	negative regulation of myeloid cell differentiation	2.695306e-2
GO:0030816	positive regulation of cAMP metabolic process	2.710051e-2
GO:0014894	response to denervation involved in regulation of muscle adaptation	2.715366e-2
GO:0021895	cerebral cortex neuron differentiation	2.721936e-2
GO:0018208	peptidyl-proline modification	2.728654e-2
GO:0007141	male meiosis I	2.734574e-2
GO:0046501	protoporphyrinogen IX metabolic process	2.764854e-2
GO:0009253	peptidoglycan catabolic process	2.764854e-2
GO:0031284	positive regulation of guanylate cyclase activity	2.777167e-2
GO:0045175	basal protein localization	2.777167e-2
GO:0050746	regulation of lipoprotein metabolic process	2.790949e-2
GO:0014826	vein smooth muscle contraction	2.790949e-2
GO:0048205	COPI coating of Golgi vesicle	2.790949e-2
GO:0051650	establishment of vesicle localization	2.815197e-2
GO:0060658	nipple morphogenesis	2.820540e-2
GO:0010424	DNA methylation on cytosine within a CG sequence	2.820540e-2
GO:0042420	dopamine catabolic process	2.841539e-2
GO:0042274	ribosomal small subunit biogenesis	2.849474e-2
GO:0046879	hormone secretion	2.857982e-2
GO:0006903	vesicle targeting	2.869793e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0006178	guanine salvage	1.340433e-9
GO:0032264	IMP salvage	1.340433e-9
GO:0046038	GMP catabolic process	1.340433e-9
GO:0032263	GMP salvage	1.340433e-9
GO:0040034	regulation of development, heterochronic	8.213969e-9
GO:0048505	regulation of timing of cell differentiation	1.289568e-8
GO:0046984	regulation of hemoglobin biosynthetic process	2.937664e-8
GO:0043252	sodium-independent organic anion transport	3.715944e-8
GO:0045964	positive regulation of dopamine metabolic process	5.634098e-8
GO:0021895	cerebral cortex neuron differentiation	1.573386e-7
GO:0031427	response to methotrexate	2.036187e-7
GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	2.270348e-7
GO:0009060	aerobic respiration	5.095768e-7
GO:0043103	hypoxanthine salvage	6.689571e-7
GO:0006168	adenine salvage	6.689571e-7
GO:0032261	purine nucleotide salvage	6.689571e-7
GO:0006188	IMP biosynthetic process	9.860728e-7
GO:0009169	purine ribonucleoside monophosphate catabolic process	1.110247e-6
GO:0006099	tricarboxylic acid cycle	1.720093e-6
GO:0046985	positive regulation of hemoglobin biosynthetic process	1.876824e-6
GO:0043973	histone H3-K4 acetylation	1.876824e-6
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	1.876824e-6
GO:0051642	centrosome localization	1.926702e-6
GO:0035815	positive regulation of renal sodium excretion	2.899887e-6
GO:0016558	protein import into peroxisome matrix	3.439925e-6
GO:0048245	eosinophil chemotaxis	4.213616e-6
GO:0042482	positive regulation of odontogenesis	6.321508e-6
GO:0046356	acetyl-CoA catabolic process	6.323901e-6
GO:0021794	thalamus development	9.521361e-6
GO:0043173	nucleotide salvage	1.289014e-5
GO:0034048	negative regulation of protein phosphatase type 2A activity	1.332725e-5
GO:0072272	proximal/distal pattern formation involved in metanephric nephron development	1.541942e-5
GO:0043096	purine base salvage	1.801970e-5
GO:0070869	heterochromatin formation involved in chromatin silencing	1.901095e-5
GO:0034441	plasma lipoprotein particle oxidation	1.901095e-5
GO:0060319	primitive erythrocyte differentiation	2.114407e-5
GO:0006625	protein targeting to peroxisome	2.364377e-5
GO:0006177	GMP biosynthetic process	2.478655e-5
GO:0006408	snRNA export from nucleus	2.534261e-5
GO:0007625	grooming behavior	2.903679e-5
GO:0042703	menstruation	3.108640e-5
GO:0050928	negative regulation of positive chemotaxis	3.108640e-5
GO:0019101	female somatic sex determination	3.108640e-5
GO:0035813	regulation of renal sodium excretion	3.626229e-5
GO:0060271	cilium morphogenesis	3.822889e-5
GO:0006421	asparaginyl-tRNA aminoacylation	4.475103e-5
GO:0021954	central nervous system neuron development	4.768719e-5
GO:0051187	cofactor catabolic process	5.163738e-5
GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly	5.821562e-5
GO:0003094	glomerular filtration	5.821562e-5
GO:0014057	positive regulation of acetylcholine secretion	6.659318e-5
GO:0009109	coenzyme catabolic process	6.887817e-5
GO:0018364	peptidyl-glutamine methylation	7.446860e-5
GO:0035026	leading edge cell differentiation	8.508613e-5
GO:0007616	long-term memory	8.640199e-5
GO:0009067	aspartate family amino acid biosynthetic process	9.678497e-5
GO:0006566	threonine metabolic process	9.978225e-5
GO:0009817	defense response to fungus, incompatible interaction	1.180267e-4
GO:0071394	cellular response to testosterone stimulus	1.212563e-4
GO:0051126	negative regulation of actin nucleation	1.268146e-4
GO:0035674	tricarboxylic acid transmembrane transport	1.268146e-4
GO:0002551	mast cell chemotaxis	1.268146e-4
GO:0009088	threonine biosynthetic process	1.268146e-4
GO:0021764	amygdala development	1.268146e-4
GO:0009113	purine base biosynthetic process	1.314080e-4
GO:0035573	N-terminal peptidyl-serine trimethylation	1.520554e-4
GO:0045872	positive regulation of rhodopsin gene expression	1.520554e-4
GO:0035572	N-terminal peptidyl-serine dimethylation	1.520554e-4
GO:0002534	cytokine production involved in inflammatory response	1.520554e-4
GO:0034276	kynurenic acid biosynthetic process	1.520554e-4
GO:0018012	N-terminal peptidyl-alanine trimethylation	1.520554e-4
GO:0018016	N-terminal peptidyl-proline dimethylation	1.520554e-4
GO:0001938	positive regulation of endothelial cell proliferation	1.554697e-4
GO:0051365	cellular response to potassium ion starvation	1.689707e-4
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	1.689707e-4
GO:0042747	circadian sleep/wake cycle, REM sleep	1.689707e-4
GO:0006668	sphinganine-1-phosphate metabolic process	1.689707e-4
GO:0051030	snRNA transport	1.795910e-4
GO:0044330	canonical Wnt receptor signaling pathway involved in positive regulation of wound healing	1.795910e-4
GO:0044328	canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration	1.795910e-4
GO:0044329	canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion	1.795910e-4
GO:0044062	regulation of excretion	1.888864e-4
GO:0045665	negative regulation of neuron differentiation	1.923709e-4
GO:0007184	SMAD protein import into nucleus	1.992600e-4
GO:0016068	type I hypersensitivity	2.213873e-4
GO:0007031	peroxisome organization	2.260335e-4
GO:0002513	tolerance induction to self antigen	2.295643e-4
GO:0006419	alanyl-tRNA aminoacylation	2.307901e-4
GO:0009066	aspartate family amino acid metabolic process	2.373775e-4
GO:0010724	regulation of definitive erythrocyte differentiation	2.514120e-4
GO:0007620	copulation	3.017836e-4
GO:0071872	cellular response to epinephrine stimulus	3.095990e-4
GO:0060829	negative regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation	3.384693e-4
GO:0051279	regulation of release of sequestered calcium ion into cytosol	3.418169e-4
GO:0021885	forebrain cell migration	3.435429e-4
GO:0021935	cerebellar granule cell precursor tangential migration	3.614192e-4
GO:0018158	protein oxidation	3.614192e-4
GO:0060137	maternal process involved in parturition	3.719660e-4
GO:0048733	sebaceous gland development	3.719660e-4
GO:0048144	fibroblast proliferation	4.086104e-4
GO:0006084	acetyl-CoA metabolic process	4.172306e-4
GO:0060215	primitive hemopoiesis	4.341247e-4
GO:0032230	positive regulation of synaptic transmission, GABAergic	4.494432e-4
GO:0006166	purine ribonucleoside salvage	4.618334e-4
GO:0072268	pattern specification involved in metanephros development	4.662501e-4
GO:0071549	cellular response to dexamethasone stimulus	4.818737e-4
GO:0051567	histone H3-K9 methylation	4.823503e-4
GO:0006144	purine base metabolic process	4.976549e-4
GO:0018993	somatic sex determination	5.593369e-4
GO:0009912	auditory receptor cell fate commitment	5.611331e-4
GO:0032796	uropod organization	5.790095e-4
GO:0031444	slow-twitch skeletal muscle fiber contraction	5.790095e-4
GO:0043248	proteasome assembly	5.856473e-4
GO:0021953	central nervous system neuron differentiation	5.942999e-4
GO:0006333	chromatin assembly or disassembly	6.137911e-4
GO:0033314	mitotic cell cycle DNA replication checkpoint	6.458522e-4
GO:0000963	mitochondrial RNA processing	6.458522e-4
GO:0046599	regulation of centriole replication	6.696426e-4
GO:2000117	negative regulation of cysteine-type endopeptidase activity	6.817350e-4
GO:0071773	cellular response to BMP stimulus	6.955356e-4
GO:0071385	cellular response to glucocorticoid stimulus	7.040311e-4
GO:0021952	central nervous system projection neuron axonogenesis	7.250869e-4
GO:0070684	seminal clot liquefaction	7.381337e-4
GO:0031497	chromatin assembly	7.574135e-4
GO:0090244	Wnt receptor signaling pathway involved in somitogenesis	7.990420e-4
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	8.218604e-4
GO:0043084	penile erection	8.703929e-4
GO:0009957	epidermal cell fate specification	8.703929e-4
GO:0090231	regulation of spindle checkpoint	8.975100e-4
GO:0010824	regulation of centrosome duplication	9.302965e-4
GO:0003329	pancreatic PP cell fate commitment	9.475406e-4
GO:0003326	pancreatic A cell fate commitment	9.475406e-4
GO:0051482	elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger	9.482625e-4
GO:0030182	neuron differentiation	1.035715e-3
GO:0031022	nuclear migration along microfilament	1.054725e-3
GO:0071526	semaphorin-plexin signaling pathway	1.066491e-3
GO:0042851	L-alanine metabolic process	1.109259e-3
GO:0060164	regulation of timing of neuron differentiation	1.116139e-3
GO:0002118	aggressive behavior	1.118848e-3
GO:0015746	citrate transport	1.184049e-3
GO:0035928	rRNA import into mitochondrion	1.239504e-3
GO:0010669	epithelial structure maintenance	1.282229e-3
GO:0021819	layer formation in cerebral cortex	1.313649e-3
GO:0014047	glutamate secretion	1.335524e-3
GO:0043094	cellular metabolic compound salvage	1.340865e-3
GO:0043461	proton-transporting ATP synthase complex assembly	1.341914e-3
GO:0022029	telencephalon cell migration	1.485186e-3
GO:0014824	artery smooth muscle contraction	1.516369e-3
GO:0042270	protection from natural killer cell mediated cytotoxicity	1.615477e-3
GO:0048659	smooth muscle cell proliferation	1.647616e-3
GO:0045081	negative regulation of interleukin-10 biosynthetic process	1.647616e-3
GO:0032780	negative regulation of ATPase activity	1.647616e-3
GO:0070267	oncosis	1.764223e-3
GO:0051882	mitochondrial depolarization	1.765631e-3
GO:0060580	ventral spinal cord interneuron fate determination	1.765631e-3
GO:0070899	mitochondrial tRNA wobble uridine modification	1.765631e-3
GO:0051684	maintenance of Golgi location	1.765631e-3
GO:0000966	RNA 5'-end processing	1.765631e-3
GO:0003327	type B pancreatic cell fate commitment	1.765631e-3
GO:0042443	phenylethylamine metabolic process	1.765631e-3
GO:0043101	purine-containing compound salvage	1.784979e-3
GO:0045989	positive regulation of striated muscle contraction	1.851098e-3
GO:0045638	negative regulation of myeloid cell differentiation	2.005408e-3
GO:0043932	ossification involved in bone remodeling	2.024162e-3
GO:0051414	response to cortisol stimulus	2.031268e-3
GO:0034770	histone H4-K20 methylation	2.066648e-3
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	2.125037e-3
GO:0097084	vascular smooth muscle cell development	2.177639e-3
GO:0045066	regulatory T cell differentiation	2.177939e-3
GO:0003188	heart valve formation	2.212501e-3
GO:0046502	uroporphyrinogen III metabolic process	2.214226e-3
GO:0071422	succinate transmembrane transport	2.214226e-3
GO:0060968	regulation of gene silencing	2.228515e-3
GO:0007221	positive regulation of transcription of Notch receptor target	2.382608e-3
GO:0034619	cellular chaperone-mediated protein complex assembly	2.419023e-3
GO:0021965	spinal cord ventral commissure morphogenesis	2.534336e-3
GO:0010025	wax biosynthetic process	2.534336e-3
GO:0071548	response to dexamethasone stimulus	2.596847e-3
GO:0018202	peptidyl-histidine modification	2.603028e-3
GO:0033566	gamma-tubulin complex localization	2.645843e-3
GO:0032185	septin cytoskeleton organization	2.645843e-3
GO:0045931	positive regulation of mitotic cell cycle	2.760493e-3
GO:0007097	nuclear migration	2.885743e-3
GO:0021960	anterior commissure morphogenesis	2.885743e-3
GO:0042637	catagen	2.910731e-3
GO:0030237	female sex determination	2.921005e-3
GO:0043949	regulation of cAMP-mediated signaling	3.057682e-3
GO:0021795	cerebral cortex cell migration	3.083887e-3
GO:0021801	cerebral cortex radial glia guided migration	3.230996e-3
GO:0006653	1,2-diacyl-sn-glycero-3-phosphocholine metabolic process	3.338878e-3
GO:0001712	ectodermal cell fate commitment	3.338878e-3
GO:0045090	retroviral genome replication	3.379207e-3
GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	3.486633e-3
GO:0043353	enucleate erythrocyte differentiation	3.549235e-3
GO:0003195	tricuspid valve formation	3.565316e-3
GO:0021799	cerebral cortex radially oriented cell migration	3.656397e-3
GO:0072078	nephron tubule morphogenesis	3.711738e-3
GO:0007224	smoothened signaling pathway	3.760337e-3
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	3.788055e-3
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	3.799781e-3
GO:0042713	sperm ejaculation	3.836224e-3
GO:0042417	dopamine metabolic process	4.189206e-3
GO:0033240	positive regulation of cellular amine metabolic process	4.275587e-3
GO:0071243	cellular response to arsenic-containing substance	4.492547e-3
GO:0046037	GMP metabolic process	4.580260e-3
GO:0045637	regulation of myeloid cell differentiation	4.634429e-3
GO:0006603	phosphocreatine metabolic process	4.646857e-3
GO:0045074	regulation of interleukin-10 biosynthetic process	4.695604e-3
GO:0043535	regulation of blood vessel endothelial cell migration	4.902522e-3
GO:0046874	quinolinate metabolic process	5.138512e-3
GO:0035810	positive regulation of urine volume	5.165362e-3
GO:0072560	type B pancreatic cell maturation	5.223040e-3
GO:0051660	establishment of centrosome localization	5.223040e-3
GO:0021540	corpus callosum morphogenesis	5.223040e-3
GO:0031507	heterochromatin formation	5.490466e-3
GO:0048858	cell projection morphogenesis	5.545150e-3
GO:0016476	regulation of embryonic cell shape	5.576725e-3
GO:0046986	negative regulation of hemoglobin biosynthetic process	5.659761e-3
GO:0032853	positive regulation of Ran GTPase activity	5.659761e-3
GO:0010996	response to auditory stimulus	5.659761e-3
GO:0043537	negative regulation of blood vessel endothelial cell migration	5.704154e-3
GO:0006457	protein folding	5.944966e-3
GO:0030917	midbrain-hindbrain boundary development	6.192259e-3
GO:0043487	regulation of RNA stability	6.192375e-3
GO:0060375	regulation of mast cell differentiation	6.436886e-3
GO:0090076	relaxation of skeletal muscle	6.507682e-3
GO:0032470	elevation of endoplasmic reticulum calcium ion concentration	6.507682e-3
GO:0046394	carboxylic acid biosynthetic process	6.611648e-3
GO:0043488	regulation of mRNA stability	6.646531e-3
GO:0045333	cellular respiration	6.653642e-3
GO:0045657	positive regulation of monocyte differentiation	6.662994e-3
GO:0003192	mitral valve formation	6.662994e-3
GO:0070050	neuron homeostasis	6.799735e-3
GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process	6.980773e-3
GO:0070831	basement membrane assembly	6.980773e-3
GO:0046605	regulation of centrosome cycle	7.018425e-3
GO:0033108	mitochondrial respiratory chain complex assembly	7.018425e-3
GO:2000053	regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	7.271808e-3
GO:0003062	regulation of heart rate by chemical signal	7.271808e-3
GO:0001973	adenosine receptor signaling pathway	7.271808e-3
GO:0006685	sphingomyelin catabolic process	7.403768e-3
GO:0000076	DNA replication checkpoint	7.403768e-3
GO:0003341	cilium movement	7.420359e-3
GO:0032990	cell part morphogenesis	7.456549e-3
GO:0016578	histone deubiquitination	7.499962e-3
GO:0045446	endothelial cell differentiation	7.686268e-3
GO:0071277	cellular response to calcium ion	7.782432e-3
GO:0014902	myotube differentiation	7.872823e-3
GO:0032012	regulation of ARF protein signal transduction	7.985963e-3
GO:0045655	regulation of monocyte differentiation	8.204912e-3
GO:0048702	embryonic neurocranium morphogenesis	8.284019e-3
GO:0006108	malate metabolic process	8.284019e-3
GO:0090026	positive regulation of monocyte chemotaxis	8.497723e-3
GO:0051131	chaperone-mediated protein complex assembly	8.510573e-3
GO:0045040	protein import into mitochondrial outer membrane	8.510573e-3
GO:0045654	positive regulation of megakaryocyte differentiation	8.510573e-3
GO:0007214	gamma-aminobutyric acid signaling pathway	8.521138e-3
GO:0051220	cytoplasmic sequestering of protein	8.637498e-3
GO:0006780	uroporphyrinogen III biosynthetic process	8.668106e-3
GO:0034776	response to histamine	8.668106e-3
GO:0006258	UDP-glucose catabolic process	8.668106e-3
GO:0090273	regulation of somatostatin secretion	8.960156e-3
GO:0003323	type B pancreatic cell development	9.003549e-3
GO:0003175	tricuspid valve development	9.003549e-3
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	9.017170e-3
GO:0045046	protein import into peroxisome membrane	9.017170e-3
GO:0003221	right ventricular cardiac muscle tissue morphogenesis	9.017170e-3
GO:2000162	negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis	9.088673e-3
GO:2000164	negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis	9.088673e-3
GO:2000166	negative regulation of planar cell polarity pathway involved in pericardium morphogenesis	9.088673e-3
GO:2000168	negative regulation of planar cell polarity pathway involved in neural tube closure	9.088673e-3
GO:2000149	negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis	9.088673e-3
GO:2000151	negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	9.088673e-3
GO:2000055	positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	9.088673e-3
GO:0033572	transferrin transport	9.088673e-3
GO:0002541	activation of plasma proteins involved in acute inflammatory response	9.088673e-3
GO:0046952	ketone body catabolic process	9.088673e-3
GO:0061310	canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development	9.088673e-3
GO:0050935	iridophore differentiation	9.177356e-3
GO:0048937	lateral line nerve glial cell development	9.177356e-3
GO:0021533	cell differentiation in hindbrain	9.182605e-3
GO:0048268	clathrin coat assembly	9.365267e-3
GO:0050918	positive chemotaxis	9.517991e-3
GO:0035522	monoubiquitinated histone H2A deubiquitination	9.630854e-3
GO:0071722	detoxification of arsenic-containing substance	9.630854e-3
GO:0071726	cellular response to diacyl bacterial lipopeptide	9.630854e-3
GO:0042496	detection of diacyl bacterial lipopeptide	9.630854e-3
GO:0071354	cellular response to interleukin-6	9.920460e-3
GO:0071173	spindle assembly checkpoint	9.978262e-3
GO:0071108	protein K48-linked deubiquitination	9.978262e-3
GO:0006901	vesicle coating	1.013976e-2
GO:0009152	purine ribonucleotide biosynthetic process	1.048818e-2
GO:0051788	response to misfolded protein	1.063062e-2
GO:0050765	negative regulation of phagocytosis	1.063062e-2
GO:0060948	cardiac vascular smooth muscle cell development	1.067921e-2
GO:0010936	negative regulation of macrophage cytokine production	1.067921e-2
GO:0019049	evasion of host defenses by virus	1.067921e-2
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	1.085744e-2
GO:0031959	mineralocorticoid receptor signaling pathway	1.085744e-2
GO:0003349	epicardium-derived cardiac endothelial cell differentiation	1.085744e-2
GO:0006529	asparagine biosynthetic process	1.085744e-2
GO:0046856	phosphatidylinositol dephosphorylation	1.096165e-2
GO:0016226	iron-sulfur cluster assembly	1.096165e-2
GO:0000271	polysaccharide biosynthetic process	1.103017e-2
GO:0032354	response to follicle-stimulating hormone stimulus	1.103324e-2
GO:0009086	methionine biosynthetic process	1.155043e-2
GO:0030149	sphingolipid catabolic process	1.155203e-2
GO:0021874	Wnt receptor signaling pathway involved in forebrain neuroblast division	1.157136e-2
GO:0090245	axis elongation involved in somitogenesis	1.157136e-2
GO:0045646	regulation of erythrocyte differentiation	1.171237e-2
GO:0046112	nucleobase biosynthetic process	1.189510e-2
GO:0030219	megakaryocyte differentiation	1.189510e-2
GO:0051661	maintenance of centrosome location	1.244753e-2
GO:0018009	N-terminal peptidyl-L-cysteine N-palmitoylation	1.244753e-2
GO:0090102	cochlea development	1.278350e-2
GO:0001845	phagolysosome assembly	1.293821e-2
GO:0021903	rostrocaudal neural tube patterning	1.299800e-2
GO:0045599	negative regulation of fat cell differentiation	1.304396e-2
GO:0032981	mitochondrial respiratory chain complex I assembly	1.308038e-2
GO:0032319	regulation of Rho GTPase activity	1.320225e-2
GO:0010522	regulation of calcium ion transport into cytosol	1.325509e-2
GO:0031448	positive regulation of fast-twitch skeletal muscle fiber contraction	1.338047e-2
GO:0016101	diterpenoid metabolic process	1.341627e-2
GO:0031365	N-terminal protein amino acid modification	1.357071e-2
GO:0006555	methionine metabolic process	1.357071e-2
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	1.360015e-2
GO:0090303	positive regulation of wound healing	1.418947e-2
GO:0046007	negative regulation of activated T cell proliferation	1.418947e-2
GO:0031947	negative regulation of glucocorticoid biosynthetic process	1.418947e-2
GO:0044340	canonical Wnt receptor signaling pathway involved in regulation of cell proliferation	1.418947e-2
GO:0090292	nuclear matrix anchoring at nuclear membrane	1.445047e-2
GO:0001830	trophectodermal cell fate commitment	1.445047e-2
GO:0006405	RNA export from nucleus	1.463742e-2
GO:0043519	regulation of myosin II filament organization	1.471259e-2
GO:0090286	cytoskeletal anchoring at nuclear membrane	1.527225e-2
GO:0061181	regulation of chondrocyte development	1.527225e-2
GO:0021644	vagus nerve morphogenesis	1.527225e-2
GO:0046882	negative regulation of follicle-stimulating hormone secretion	1.527225e-2
GO:0003158	endothelium development	1.536198e-2
GO:0021564	vagus nerve development	1.549233e-2
GO:0006334	nucleosome assembly	1.575306e-2
GO:0051492	regulation of stress fiber assembly	1.584148e-2
GO:0033504	floor plate development	1.621485e-2
GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose	1.621485e-2
GO:0051590	positive regulation of neurotransmitter transport	1.627133e-2
GO:0045023	G0 to G1 transition	1.702609e-2
GO:0097152	mesenchymal cell apoptosis	1.702609e-2
GO:0042492	gamma-delta T cell differentiation	1.702609e-2
GO:0014028	notochord formation	1.702609e-2
GO:0014819	regulation of skeletal muscle contraction	1.703037e-2
GO:0001702	gastrulation with mouth forming second	1.714848e-2
GO:0031577	spindle checkpoint	1.757370e-2
GO:0090277	positive regulation of peptide hormone secretion	1.762549e-2
GO:0021955	central nervous system neuron axonogenesis	1.767651e-2
GO:0048683	regulation of collateral sprouting of intact axon in response to injury	1.774461e-2
GO:0045329	carnitine biosynthetic process	1.774461e-2
GO:0006669	sphinganine-1-phosphate biosynthetic process	1.774461e-2
GO:0046520	sphingoid biosynthetic process	1.775522e-2
GO:0010171	body morphogenesis	1.782302e-2
GO:0046466	membrane lipid catabolic process	1.784226e-2
GO:0000097	sulfur amino acid biosynthetic process	1.786836e-2
GO:0070933	histone H4 deacetylation	1.794567e-2
GO:0007567	parturition	1.794567e-2
GO:0050779	RNA destabilization	1.843106e-2
GO:0048539	bone marrow development	1.843106e-2
GO:0060112	generation of ovulation cycle rhythm	1.852357e-2
GO:0060802	epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification	1.852357e-2
GO:0090010	transforming growth factor beta receptor signaling pathway involved in primitive streak formation	1.852357e-2
GO:0046683	response to organophosphorus	1.852357e-2
GO:0048327	axial mesodermal cell fate specification	1.852357e-2
GO:0016482	cytoplasmic transport	1.852357e-2
GO:0002085	inhibition of neuroepithelial cell differentiation	1.852357e-2
GO:0001988	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	1.852357e-2
GO:0007518	myoblast cell fate determination	1.852357e-2
GO:0014908	myotube differentiation involved in skeletal muscle regeneration	1.852357e-2
GO:0003171	atrioventricular valve development	1.952887e-2
GO:0010172	embryonic body morphogenesis	1.956626e-2
GO:0034968	histone lysine methylation	1.957765e-2
GO:0050919	negative chemotaxis	1.958984e-2
GO:0032970	regulation of actin filament-based process	1.961733e-2
GO:0016071	mRNA metabolic process	1.962901e-2
GO:0008053	mitochondrial fusion	1.965709e-2
GO:0001502	cartilage condensation	1.972282e-2
GO:0045750	positive regulation of S phase of mitotic cell cycle	1.973986e-2
GO:0035058	nonmotile primary cilium assembly	1.978238e-2
GO:0061333	renal tubule morphogenesis	1.982180e-2
GO:0006942	regulation of striated muscle contraction	2.040256e-2
GO:0048663	neuron fate commitment	2.073464e-2
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.074624e-2
GO:0032926	negative regulation of activin receptor signaling pathway	2.074624e-2
GO:0006323	DNA packaging	2.080145e-2
GO:0032693	negative regulation of interleukin-10 production	2.084556e-2
GO:0006734	NADH metabolic process	2.087590e-2
GO:0035304	regulation of protein dephosphorylation	2.093770e-2
GO:0070723	response to cholesterol	2.104010e-2
GO:0051561	elevation of mitochondrial calcium ion concentration	2.128449e-2
GO:0031943	regulation of glucocorticoid metabolic process	2.128449e-2
GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport	2.146924e-2
GO:0070935	3'-UTR-mediated mRNA stabilization	2.146924e-2
GO:0044332	Wnt receptor signaling pathway involved in dorsal/ventral axis specification	2.146924e-2
GO:0021530	spinal cord oligodendrocyte cell fate specification	2.146924e-2
GO:0009125	nucleoside monophosphate catabolic process	2.212539e-2
GO:0072282	metanephric nephron tubule morphogenesis	2.229060e-2
GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	2.229060e-2
GO:0015881	creatine transport	2.241868e-2
GO:0015680	intracellular copper ion transport	2.241868e-2
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	2.265015e-2
GO:0002793	positive regulation of peptide secretion	2.286651e-2
GO:0035601	protein deacylation	2.319941e-2
GO:0010799	regulation of peptidyl-threonine phosphorylation	2.336670e-2
GO:0045647	negative regulation of erythrocyte differentiation	2.377478e-2
GO:0001936	regulation of endothelial cell proliferation	2.390532e-2
GO:0070460	thyroid-stimulating hormone secretion	2.390656e-2
GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	2.390656e-2
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	2.390656e-2
GO:0015827	tryptophan transport	2.390656e-2
GO:0007094	mitotic cell cycle spindle assembly checkpoint	2.414812e-2
GO:0030071	regulation of mitotic metaphase/anaphase transition	2.432436e-2
GO:0021513	spinal cord dorsal/ventral patterning	2.554033e-2
GO:0018027	peptidyl-lysine dimethylation	2.588199e-2
GO:0006164	purine nucleotide biosynthetic process	2.612856e-2
GO:0048755	branching morphogenesis of a nerve	2.629678e-2
GO:0031536	positive regulation of exit from mitosis	2.629678e-2
GO:0071174	mitotic cell cycle spindle checkpoint	2.663796e-2
GO:0061113	pancreas morphogenesis	2.663796e-2
GO:0003065	positive regulation of heart rate by epinephrine	2.663796e-2
GO:0009950	dorsal/ventral axis specification	2.668140e-2
GO:0032321	positive regulation of Rho GTPase activity	2.693770e-2
GO:0030902	hindbrain development	2.704782e-2
GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation	2.736079e-2
GO:0060285	ciliary cell motility	2.736079e-2
GO:0002074	extraocular skeletal muscle development	2.736079e-2
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	2.742081e-2
GO:0046513	ceramide biosynthetic process	2.786074e-2
GO:0045793	positive regulation of cell size	2.819526e-2
GO:0061014	positive regulation of mRNA catabolic process	2.850903e-2
GO:0001842	neural fold formation	2.850903e-2
GO:0001675	acrosome assembly	2.850903e-2
GO:0043922	negative regulation by host of viral transcription	2.869630e-2
GO:0048240	sperm capacitation	2.894297e-2
GO:0032228	regulation of synaptic transmission, GABAergic	2.895035e-2
GO:0032925	regulation of activin receptor signaling pathway	2.904197e-2
GO:0032233	positive regulation of actin filament bundle assembly	2.919988e-2
GO:0046785	microtubule polymerization	2.934585e-2
GO:0006476	protein deacetylation	2.946778e-2
GO:0035499	carnosine biosynthetic process	2.969554e-2
GO:0051926	negative regulation of calcium ion transport	3.012389e-2
GO:0006450	regulation of translational fidelity	3.025651e-2
GO:0035307	positive regulation of protein dephosphorylation	3.044173e-2
GO:0032956	regulation of actin cytoskeleton organization	3.047606e-2
GO:0021535	cell migration in hindbrain	3.071215e-2
GO:0032897	negative regulation of viral transcription	3.094099e-2
GO:0042276	error-prone translesion synthesis	3.111622e-2
GO:0032277	negative regulation of gonadotropin secretion	3.111622e-2
GO:0032011	ARF protein signal transduction	3.111622e-2
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	3.111622e-2
GO:0033143	regulation of steroid hormone receptor signaling pathway	3.113929e-2
GO:0006898	receptor-mediated endocytosis	3.169108e-2
GO:0003181	atrioventricular valve morphogenesis	3.169949e-2
GO:0034629	cellular protein complex localization	3.212887e-2
GO:0010569	regulation of double-strand break repair via homologous recombination	3.212887e-2
GO:0010458	exit from mitosis	3.212887e-2
GO:0035306	positive regulation of dephosphorylation	3.229953e-2
GO:0006670	sphingosine metabolic process	3.229953e-2
GO:0022900	electron transport chain	3.230654e-2
GO:0048298	positive regulation of isotype switching to IgA isotypes	3.261783e-2
GO:0048708	astrocyte differentiation	3.262403e-2
GO:0007320	insemination	3.270791e-2
GO:0051646	mitochondrion localization	3.287112e-2
GO:0015671	oxygen transport	3.324168e-2
GO:0032318	regulation of Ras GTPase activity	3.331340e-2
GO:0006939	smooth muscle contraction	3.393021e-2
GO:0001975	response to amphetamine	3.409867e-2
GO:0002761	regulation of myeloid leukocyte differentiation	3.417518e-2
GO:0060037	pharyngeal system development	3.436649e-2
GO:0045652	regulation of megakaryocyte differentiation	3.464167e-2
GO:0072086	specification of loop of Henle identity	3.513804e-2
GO:2000095	regulation of Wnt receptor signaling pathway, planar cell polarity pathway	3.513804e-2
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.513804e-2
GO:0007099	centriole replication	3.513804e-2
GO:0000959	mitochondrial RNA metabolic process	3.513804e-2
GO:0060434	bronchus morphogenesis	3.517898e-2
GO:0061002	negative regulation of dendritic spine morphogenesis	3.517898e-2
GO:0045608	negative regulation of auditory receptor cell differentiation	3.517898e-2
GO:0060014	granulosa cell differentiation	3.517898e-2
GO:0030579	ubiquitin-dependent SMAD protein catabolic process	3.517898e-2
GO:2000078	positive regulation of type B pancreatic cell development	3.533490e-2
GO:0071733	transcriptional activation by promoter-enhancer looping	3.533490e-2
GO:0046501	protoporphyrinogen IX metabolic process	3.533490e-2
GO:0035106	operant conditioning	3.565065e-2
GO:0007023	post-chaperonin tubulin folding pathway	3.565065e-2
GO:0048664	neuron fate determination	3.598115e-2
GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	3.611746e-2
GO:0045607	regulation of auditory receptor cell differentiation	3.611746e-2
GO:0031623	receptor internalization	3.617878e-2
GO:0021984	adenohypophysis development	3.622680e-2
GO:0035914	skeletal muscle cell differentiation	3.664649e-2
GO:0002062	chondrocyte differentiation	3.699371e-2
GO:0060322	head development	3.713823e-2
GO:0051340	regulation of ligase activity	3.726279e-2