Novel motif:7

name:	motif7_CGNATC

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0042506	tyrosine phosphorylation of Stat5 protein	1.000792e-9
GO:0045911	positive regulation of DNA recombination	1.359701e-8
GO:0000018	regulation of DNA recombination	3.199208e-8
GO:0000416	positive regulation of histone H3-K36 methylation	1.342466e-7
GO:0045830	positive regulation of isotype switching	2.619284e-7
GO:0006289	nucleotide-excision repair	4.057882e-7
GO:0009145	purine nucleoside triphosphate biosynthetic process	4.785308e-7
GO:0097151	positive regulation of inhibitory postsynaptic membrane potential	4.991831e-7
GO:0045684	positive regulation of epidermis development	7.437033e-7
GO:0009142	nucleoside triphosphate biosynthetic process	8.064215e-7
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	1.414701e-6
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	2.061730e-6
GO:0006164	purine nucleotide biosynthetic process	2.215631e-6
GO:0006344	maintenance of chromatin silencing	2.368030e-6
GO:0046939	nucleotide phosphorylation	2.501689e-6
GO:0006458	'de novo' protein folding	2.578128e-6
GO:0043044	ATP-dependent chromatin remodeling	3.371423e-6
GO:0015862	uridine transport	3.400193e-6
GO:0009201	ribonucleoside triphosphate biosynthetic process	3.665556e-6
GO:0072522	purine-containing compound biosynthetic process	3.737012e-6
GO:0043486	histone exchange	3.915035e-6
GO:0030579	ubiquitin-dependent SMAD protein catabolic process	4.115393e-6
GO:0021592	fourth ventricle development	4.199366e-6
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	4.801687e-6
GO:0045109	intermediate filament organization	4.849918e-6
GO:0021993	initiation of neural tube closure	5.460653e-6
GO:0034470	ncRNA processing	5.986497e-6
GO:0035344	hypoxanthine transport	7.225038e-6
GO:0035364	thymine transport	7.225038e-6
GO:0015854	guanine transport	7.225038e-6
GO:0006283	transcription-coupled nucleotide-excision repair	7.390495e-6
GO:0042866	pyruvate biosynthetic process	7.839401e-6
GO:0009071	serine family amino acid catabolic process	8.828777e-6
GO:0032472	Golgi calcium ion transport	9.665951e-6
GO:0030026	cellular manganese ion homeostasis	9.665951e-6
GO:0032468	Golgi calcium ion homeostasis	9.665951e-6
GO:0006271	DNA strand elongation involved in DNA replication	9.703222e-6
GO:0015853	adenine transport	1.026845e-5
GO:0031444	slow-twitch skeletal muscle fiber contraction	1.084656e-5
GO:0006668	sphinganine-1-phosphate metabolic process	1.244729e-5
GO:0006565	L-serine catabolic process	1.255356e-5
GO:0048298	positive regulation of isotype switching to IgA isotypes	1.259223e-5
GO:0008272	sulfate transport	1.270639e-5
GO:0051084	'de novo' posttranslational protein folding	1.437510e-5
GO:0043353	enucleate erythrocyte differentiation	1.549057e-5
GO:0006754	ATP biosynthetic process	1.625828e-5
GO:0070489	T cell aggregation	1.645371e-5
GO:0035356	cellular triglyceride homeostasis	1.645371e-5
GO:0009152	purine ribonucleotide biosynthetic process	1.769206e-5
GO:0006302	double-strand break repair	1.878459e-5
GO:0072553	terminal button organization	1.926476e-5
GO:0045606	positive regulation of epidermal cell differentiation	1.984795e-5
GO:0009260	ribonucleotide biosynthetic process	1.993447e-5
GO:0006281	DNA repair	2.192122e-5
GO:0010890	positive regulation of sequestering of triglyceride	2.303645e-5
GO:0042147	retrograde transport, endosome to Golgi	2.879901e-5
GO:0048484	enteric nervous system development	2.981575e-5
GO:0014707	branchiomeric skeletal muscle development	3.111025e-5
GO:0000722	telomere maintenance via recombination	3.342147e-5
GO:0032201	telomere maintenance via semi-conservative replication	3.594533e-5
GO:0006670	sphingosine metabolic process	3.599067e-5
GO:0072303	positive regulation of glomerular metanephric mesangial cell proliferation	3.923239e-5
GO:0072126	positive regulation of glomerular mesangial cell proliferation	4.072651e-5
GO:0071506	cellular response to mycophenolic acid	4.072651e-5
GO:0021892	cerebral cortex GABAergic interneuron differentiation	4.121489e-5
GO:0034080	CenH3-containing nucleosome assembly at centromere	4.188399e-5
GO:0060087	relaxation of vascular smooth muscle	4.253963e-5
GO:0042503	tyrosine phosphorylation of Stat3 protein	4.411860e-5
GO:0031468	nuclear envelope reassembly	4.452764e-5
GO:0007184	SMAD protein import into nucleus	4.636196e-5
GO:0007413	axonal fasciculation	4.651913e-5
GO:0016073	snRNA metabolic process	5.252490e-5
GO:0006303	double-strand break repair via nonhomologous end joining	5.373371e-5
GO:0022616	DNA strand elongation	6.106866e-5
GO:0006261	DNA-dependent DNA replication	6.126531e-5
GO:0071044	histone mRNA catabolic process	6.665486e-5
GO:0006270	DNA-dependent DNA replication initiation	6.849921e-5
GO:0007431	salivary gland development	6.890255e-5
GO:0015858	nucleoside transport	7.133747e-5
GO:0019049	evasion of host defenses by virus	7.294145e-5
GO:0090150	establishment of protein localization in membrane	8.051328e-5
GO:0009259	ribonucleotide metabolic process	8.697729e-5
GO:0045110	intermediate filament bundle assembly	9.100657e-5
GO:0000414	regulation of histone H3-K36 methylation	9.100657e-5
GO:0060668	regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling	9.238295e-5
GO:0006420	arginyl-tRNA aminoacylation	1.007592e-4
GO:0071028	nuclear mRNA surveillance	1.007592e-4
GO:0015864	pyrimidine nucleoside transport	1.063701e-4
GO:0008033	tRNA processing	1.095204e-4
GO:0070192	chromosome organization involved in meiosis	1.149939e-4
GO:0007127	meiosis I	1.229097e-4
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	1.274980e-4
GO:0034660	ncRNA metabolic process	1.330961e-4
GO:0033299	secretion of lysosomal enzymes	1.370301e-4
GO:0010625	positive regulation of Schwann cell proliferation	1.408688e-4
GO:0032929	negative regulation of superoxide anion generation	1.444339e-4
GO:0009150	purine ribonucleotide metabolic process	1.483179e-4
GO:0010833	telomere maintenance via telomere lengthening	1.557312e-4
GO:0031167	rRNA methylation	1.617944e-4
GO:0090002	establishment of protein localization in plasma membrane	1.642675e-4
GO:0035093	spermatogenesis, exchange of chromosomal proteins	1.685327e-4
GO:0009205	purine ribonucleoside triphosphate metabolic process	1.888102e-4
GO:0010701	positive regulation of norepinephrine secretion	1.929813e-4
GO:0021678	third ventricle development	1.937793e-4
GO:0006260	DNA replication	1.994006e-4
GO:0002438	acute inflammatory response to antigenic stimulus	2.199673e-4
GO:0010189	vitamin E biosynthetic process	2.199673e-4
GO:0009199	ribonucleoside triphosphate metabolic process	2.239711e-4
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	2.307227e-4
GO:0009817	defense response to fungus, incompatible interaction	2.307227e-4
GO:0032287	peripheral nervous system myelin maintenance	2.316059e-4
GO:0007435	salivary gland morphogenesis	2.405745e-4
GO:0002889	regulation of immunoglobulin mediated immune response	2.612373e-4
GO:0051321	meiotic cell cycle	2.655402e-4
GO:0032383	regulation of intracellular cholesterol transport	2.674221e-4
GO:0001798	positive regulation of type IIa hypersensitivity	2.714206e-4
GO:0009144	purine nucleoside triphosphate metabolic process	2.729329e-4
GO:0007183	SMAD protein complex assembly	2.747408e-4
GO:0051588	regulation of neurotransmitter transport	2.784948e-4
GO:0000019	regulation of mitotic recombination	2.871930e-4
GO:0032967	positive regulation of collagen biosynthetic process	2.965310e-4
GO:0010520	regulation of reciprocal meiotic recombination	3.052508e-4
GO:0060445	branching involved in salivary gland morphogenesis	3.070831e-4
GO:0008334	histone mRNA metabolic process	3.074066e-4
GO:0015866	ADP transport	3.132353e-4
GO:0044253	positive regulation of multicellular organismal metabolic process	3.169496e-4
GO:0042254	ribosome biogenesis	3.263668e-4
GO:0006457	protein folding	3.345128e-4
GO:0045039	protein import into mitochondrial inner membrane	3.370703e-4
GO:2000427	positive regulation of apoptotic cell clearance	3.553267e-4
GO:0072111	cell proliferation involved in kidney development	3.578538e-4
GO:0070947	neutrophil mediated killing of fungus	3.587498e-4
GO:0002712	regulation of B cell mediated immunity	3.616495e-4
GO:0006297	nucleotide-excision repair, DNA gap filling	3.620286e-4
GO:0045191	regulation of isotype switching	3.682393e-4
GO:0046732	active induction of host immune response by virus	3.754508e-4
GO:0051580	regulation of neurotransmitter uptake	3.948132e-4
GO:0010936	negative regulation of macrophage cytokine production	3.973358e-4
GO:0000726	non-recombinational repair	4.051582e-4
GO:0034389	lipid particle organization	4.091897e-4
GO:0016191	synaptic vesicle uncoating	4.251889e-4
GO:0033490	cholesterol biosynthetic process via lathosterol	4.251889e-4
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	4.346842e-4
GO:0007339	binding of sperm to zona pellucida	4.408787e-4
GO:0006944	cellular membrane fusion	4.488372e-4
GO:0060707	trophoblast giant cell differentiation	4.512202e-4
GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity	4.539484e-4
GO:0016568	chromatin modification	4.572456e-4
GO:0006268	DNA unwinding involved in replication	4.651677e-4
GO:0045835	negative regulation of meiosis	4.774624e-4
GO:0060020	Bergmann glial cell differentiation	4.858251e-4
GO:0033605	positive regulation of catecholamine secretion	4.868746e-4
GO:0051954	positive regulation of amine transport	5.037918e-4
GO:0019883	antigen processing and presentation of endogenous antigen	5.104112e-4
GO:0046604	positive regulation of mitotic centrosome separation	5.268160e-4
GO:0010734	negative regulation of protein glutathionylation	5.291224e-4
GO:0008049	male courtship behavior	5.291224e-4
GO:0048266	behavioral response to pain	5.720902e-4
GO:0035426	extracellular matrix-cell signaling	5.738698e-4
GO:0009106	lipoate metabolic process	5.821348e-4
GO:0045792	negative regulation of cell size	5.940769e-4
GO:0043249	erythrocyte maturation	5.982214e-4
GO:0045217	cell-cell junction maintenance	6.124245e-4
GO:0031055	chromatin remodeling at centromere	6.216786e-4
GO:0007129	synapsis	6.238485e-4
GO:0007126	meiosis	6.284322e-4
GO:0072110	glomerular mesangial cell proliferation	6.636393e-4
GO:0045986	negative regulation of smooth muscle contraction	6.636393e-4
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	6.767968e-4
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	6.767968e-4
GO:0043174	nucleoside salvage	6.930874e-4
GO:0051225	spindle assembly	7.292978e-4
GO:0010430	fatty acid omega-oxidation	7.657010e-4
GO:0007131	reciprocal meiotic recombination	7.967729e-4
GO:0001941	postsynaptic membrane organization	8.035008e-4
GO:0090399	replicative senescence	8.212104e-4
GO:0060706	cell differentiation involved in embryonic placenta development	8.321784e-4
GO:0000154	rRNA modification	9.016350e-4
GO:0071593	lymphocyte aggregation	9.089903e-4
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	1.027503e-3
GO:0031120	snRNA pseudouridine synthesis	1.035401e-3
GO:0001555	oocyte growth	1.035401e-3
GO:0002882	positive regulation of chronic inflammatory response to non-antigenic stimulus	1.035401e-3
GO:0032916	positive regulation of transforming growth factor beta3 production	1.046926e-3
GO:0009141	nucleoside triphosphate metabolic process	1.107092e-3
GO:0035607	fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development	1.139567e-3
GO:0050765	negative regulation of phagocytosis	1.142288e-3
GO:0061025	membrane fusion	1.181536e-3
GO:0046730	induction of host immune response by virus	1.200162e-3
GO:0031536	positive regulation of exit from mitosis	1.200162e-3
GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	1.211838e-3
GO:0042360	vitamin E metabolic process	1.213842e-3
GO:0045618	positive regulation of keratinocyte differentiation	1.241787e-3
GO:0031284	positive regulation of guanylate cyclase activity	1.258163e-3
GO:0010693	negative regulation of alkaline phosphatase activity	1.258163e-3
GO:0006756	AMP phosphorylation	1.264165e-3
GO:0006430	lysyl-tRNA aminoacylation	1.264165e-3
GO:0032200	telomere organization	1.286008e-3
GO:0072109	glomerular mesangium development	1.289550e-3
GO:0045103	intermediate filament-based process	1.291443e-3
GO:0001830	trophectodermal cell fate commitment	1.296684e-3
GO:0070943	neutrophil mediated killing of symbiont cell	1.369965e-3
GO:0035036	sperm-egg recognition	1.409804e-3
GO:0000733	DNA strand renaturation	1.425972e-3
GO:0045347	negative regulation of MHC class II biosynthetic process	1.427863e-3
GO:0006610	ribosomal protein import into nucleus	1.438139e-3
GO:0051054	positive regulation of DNA metabolic process	1.474226e-3
GO:0090174	organelle membrane fusion	1.491893e-3
GO:0006171	cAMP biosynthetic process	1.497205e-3
GO:0002513	tolerance induction to self antigen	1.525304e-3
GO:0007195	inhibition of adenylate cyclase activity by dopamine receptor signaling pathway	1.578900e-3
GO:0006379	mRNA cleavage	1.603944e-3
GO:0071956	cellular component maintenance at cellular level	1.623341e-3
GO:0001970	positive regulation of activation of membrane attack complex	1.642289e-3
GO:0033233	regulation of protein sumoylation	1.653014e-3
GO:0035092	sperm chromatin condensation	1.654561e-3
GO:0032235	negative regulation of calcium ion transport via store-operated calcium channel activity	1.674725e-3
GO:0071025	RNA surveillance	1.674725e-3
GO:0016180	snRNA processing	1.703939e-3
GO:0006695	cholesterol biosynthetic process	1.724571e-3
GO:0071480	cellular response to gamma radiation	1.735337e-3
GO:0006515	misfolded or incompletely synthesized protein catabolic process	1.748262e-3
GO:0046952	ketone body catabolic process	1.811192e-3
GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	1.825595e-3
GO:0007004	telomere maintenance via telomerase	1.826262e-3
GO:0043587	tongue morphogenesis	1.842221e-3
GO:0035752	lysosomal lumen pH elevation	1.850585e-3
GO:0001575	globoside metabolic process	1.850585e-3
GO:0000046	autophagic vacuole fusion	1.850585e-3
GO:0045415	negative regulation of interleukin-8 biosynthetic process	1.914544e-3
GO:0044342	type B pancreatic cell proliferation	1.924256e-3
GO:0010918	positive regulation of mitochondrial membrane potential	1.924256e-3
GO:0051798	positive regulation of hair follicle development	1.931225e-3
GO:0042508	tyrosine phosphorylation of Stat1 protein	1.958367e-3
GO:0051865	protein autoubiquitination	1.964329e-3
GO:0010799	regulation of peptidyl-threonine phosphorylation	1.980061e-3
GO:2000119	negative regulation of sodium-dependent phosphate transport	2.009148e-3
GO:0008295	spermidine biosynthetic process	2.009148e-3
GO:0006563	L-serine metabolic process	2.053135e-3
GO:0007158	neuron cell-cell adhesion	2.065637e-3
GO:0007096	regulation of exit from mitosis	2.098973e-3
GO:0042699	follicle-stimulating hormone signaling pathway	2.107887e-3
GO:0072012	glomerulus vasculature development	2.207164e-3
GO:0016446	somatic hypermutation of immunoglobulin genes	2.227932e-3
GO:0010523	negative regulation of calcium ion transport into cytosol	2.234504e-3
GO:0048483	autonomic nervous system development	2.242882e-3
GO:0006312	mitotic recombination	2.338990e-3
GO:0000725	recombinational repair	2.383150e-3
GO:0015842	synaptic vesicle amine transport	2.399733e-3
GO:0010742	macrophage derived foam cell differentiation	2.423641e-3
GO:0019695	choline metabolic process	2.537663e-3
GO:0021903	rostrocaudal neural tube patterning	2.541345e-3
GO:0006256	UDP catabolic process	2.549424e-3
GO:0060252	positive regulation of glial cell proliferation	2.580199e-3
GO:0032793	positive regulation of CREB transcription factor activity	2.592430e-3
GO:0000724	double-strand break repair via homologous recombination	2.645456e-3
GO:0051298	centrosome duplication	2.664108e-3
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	2.668718e-3
GO:0097116	gephyrin clustering	2.697167e-3
GO:0051968	positive regulation of synaptic transmission, glutamatergic	2.733827e-3
GO:0060631	regulation of meiosis I	2.743282e-3
GO:0032007	negative regulation of TOR signaling cascade	2.771454e-3
GO:0034654	nucleobase-containing compound biosynthetic process	2.772223e-3
GO:0097105	presynaptic membrane assembly	2.779104e-3
GO:0003149	membranous septum morphogenesis	2.882066e-3
GO:0009446	putrescine biosynthetic process	3.034666e-3
GO:0035427	purine nucleoside transmembrane transport	3.034666e-3
GO:0006258	UDP-glucose catabolic process	3.034666e-3
GO:0034241	positive regulation of macrophage fusion	3.072353e-3
GO:0008625	induction of apoptosis via death domain receptors	3.105625e-3
GO:0010157	response to chlorate	3.157912e-3
GO:0030917	midbrain-hindbrain boundary development	3.172105e-3
GO:0010458	exit from mitosis	3.239008e-3
GO:0085029	extracellular matrix assembly	3.253656e-3
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	3.262190e-3
GO:0048210	Golgi vesicle fusion to target membrane	3.264809e-3
GO:0045218	zonula adherens maintenance	3.326490e-3
GO:0030202	heparin metabolic process	3.326490e-3
GO:0060828	regulation of canonical Wnt receptor signaling pathway	3.334052e-3
GO:0006370	mRNA capping	3.341735e-3
GO:0030206	chondroitin sulfate biosynthetic process	3.376331e-3
GO:0052200	response to host defenses	3.397592e-3
GO:0051952	regulation of amine transport	3.438082e-3
GO:0045838	positive regulation of membrane potential	3.488849e-3
GO:0006596	polyamine biosynthetic process	3.488849e-3
GO:0035645	enteric smooth muscle cell differentiation	3.509534e-3
GO:0003339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	3.581775e-3
GO:0003218	cardiac left ventricle formation	3.614816e-3
GO:0070198	protein localization to chromosome, telomeric region	3.631392e-3
GO:0006325	chromatin organization	3.782261e-3
GO:0034394	protein localization at cell surface	3.788902e-3
GO:0032965	regulation of collagen biosynthetic process	3.798623e-3
GO:0022601	menstrual cycle phase	3.840922e-3
GO:0006275	regulation of DNA replication	3.867749e-3
GO:0008216	spermidine metabolic process	3.875370e-3
GO:0009649	entrainment of circadian clock	3.904932e-3
GO:0002885	positive regulation of hypersensitivity	3.917343e-3
GO:0043029	T cell homeostasis	4.015029e-3
GO:0045682	regulation of epidermis development	4.047095e-3
GO:0071218	cellular response to misfolded protein	4.058440e-3
GO:0097119	postsynaptic density protein 95 clustering	4.154525e-3
GO:0097104	postsynaptic membrane assembly	4.154525e-3
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	4.301538e-3
GO:0006278	RNA-dependent DNA replication	4.320380e-3
GO:0051152	positive regulation of smooth muscle cell differentiation	4.339266e-3
GO:0051926	negative regulation of calcium ion transport	4.516232e-3
GO:0008588	release of cytoplasmic sequestered NF-kappaB	4.570495e-3
GO:2000002	negative regulation of DNA damage checkpoint	4.572033e-3
GO:0021551	central nervous system morphogenesis	4.572033e-3
GO:0070625	zymogen granule exocytosis	4.572033e-3
GO:0022004	midbrain-hindbrain boundary maturation during brain development	4.572033e-3
GO:0021588	cerebellum formation	4.572033e-3
GO:0010982	regulation of high-density lipoprotein particle clearance	4.595659e-3
GO:0031069	hair follicle morphogenesis	4.653945e-3
GO:0019532	oxalate transport	4.738821e-3
GO:0046607	positive regulation of centrosome cycle	4.808121e-3
GO:0006529	asparagine biosynthetic process	4.808121e-3
GO:0016242	negative regulation of macroautophagy	4.808121e-3
GO:0006669	sphinganine-1-phosphate biosynthetic process	4.808121e-3
GO:0010983	positive regulation of high-density lipoprotein particle clearance	4.808121e-3
GO:0016072	rRNA metabolic process	4.893525e-3
GO:0048642	negative regulation of skeletal muscle tissue development	5.019620e-3
GO:0072124	regulation of glomerular mesangial cell proliferation	5.087884e-3
GO:0045604	regulation of epidermal cell differentiation	5.191287e-3
GO:0042149	cellular response to glucose starvation	5.202325e-3
GO:0010536	positive regulation of activation of Janus kinase activity	5.286528e-3
GO:0015904	tetracycline transport	5.294852e-3
GO:0002922	positive regulation of humoral immune response	5.480915e-3
GO:0061205	paramesonephric duct development	5.527449e-3
GO:2000466	negative regulation of glycogen (starch) synthase activity	5.527449e-3
GO:0046501	protoporphyrinogen IX metabolic process	5.527449e-3
GO:0002331	pre-B cell allelic exclusion	5.527449e-3
GO:0007260	tyrosine phosphorylation of STAT protein	5.600166e-3
GO:0000718	nucleotide-excision repair, DNA damage removal	5.601930e-3
GO:0048251	elastic fiber assembly	5.616021e-3
GO:0032910	regulation of transforming growth factor beta3 production	5.653335e-3
GO:0051026	chiasma assembly	5.744625e-3
GO:0000723	telomere maintenance	5.845059e-3
GO:0050434	positive regulation of viral transcription	5.878907e-3
GO:0060290	transdifferentiation	5.960434e-3
GO:0002092	positive regulation of receptor internalization	6.102492e-3
GO:0009247	glycolipid biosynthetic process	6.280387e-3
GO:0009107	lipoate biosynthetic process	6.288492e-3
GO:0016925	protein sumoylation	6.299782e-3
GO:0019388	galactose catabolic process	6.361411e-3
GO:0021933	radial glia guided migration of cerebellar granule cell	6.375390e-3
GO:0070179	D-serine biosynthetic process	6.375390e-3
GO:0006783	heme biosynthetic process	6.380567e-3
GO:0014059	regulation of dopamine secretion	6.416870e-3
GO:0006396	RNA processing	6.544911e-3
GO:0043932	ossification involved in bone remodeling	6.632333e-3
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	6.632333e-3
GO:0033522	histone H2A ubiquitination	6.685215e-3
GO:0051973	positive regulation of telomerase activity	6.720851e-3
GO:0032025	response to cobalt ion	6.720851e-3
GO:0006646	phosphatidylethanolamine biosynthetic process	6.720851e-3
GO:0032801	receptor catabolic process	6.856387e-3
GO:0051788	response to misfolded protein	7.066909e-3
GO:0006166	purine ribonucleoside salvage	7.107913e-3
GO:0090141	positive regulation of mitochondrial fission	7.107913e-3
GO:0006598	polyamine catabolic process	7.107913e-3
GO:0006298	mismatch repair	7.135133e-3
GO:0042796	snRNA transcription from RNA polymerase III promoter	7.202311e-3
GO:0046318	negative regulation of glucosylceramide biosynthetic process	7.202311e-3
GO:0042795	snRNA transcription from RNA polymerase II promoter	7.202311e-3
GO:0017196	N-terminal peptidyl-methionine acetylation	7.202311e-3
GO:0048755	branching morphogenesis of a nerve	7.296241e-3
GO:0046602	regulation of mitotic centrosome separation	7.345535e-3
GO:0046208	spermine catabolic process	7.375879e-3
GO:0061198	fungiform papilla formation	7.449142e-3
GO:0045414	regulation of interleukin-8 biosynthetic process	7.469077e-3
GO:0016570	histone modification	7.519353e-3
GO:0060708	spongiotrophoblast differentiation	7.529394e-3
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	7.572781e-3
GO:0018130	heterocycle biosynthetic process	7.669000e-3
GO:0050764	regulation of phagocytosis	8.123507e-3
GO:0010535	positive regulation of activation of JAK2 kinase activity	8.160560e-3
GO:0051088	PMA-inducible membrane protein ectodomain proteolysis	8.166178e-3
GO:0046039	GTP metabolic process	8.373060e-3
GO:0006525	arginine metabolic process	8.498411e-3
GO:0021555	midbrain-hindbrain boundary morphogenesis	8.510736e-3
GO:0032212	positive regulation of telomere maintenance via telomerase	8.546514e-3
GO:0051873	killing by host of symbiont cells	8.551506e-3
GO:0044246	regulation of multicellular organismal metabolic process	8.589425e-3
GO:0021837	motogenic signaling involved in postnatal olfactory bulb interneuron migration	8.638465e-3
GO:0010845	positive regulation of reciprocal meiotic recombination	8.638465e-3
GO:0034728	nucleosome organization	8.669974e-3
GO:0032508	DNA duplex unwinding	8.681384e-3
GO:0002891	positive regulation of immunoglobulin mediated immune response	8.684773e-3
GO:0045338	farnesyl diphosphate metabolic process	8.737257e-3
GO:0035518	histone H2A monoubiquitination	8.786777e-3
GO:0051414	response to cortisol stimulus	8.811089e-3
GO:0045843	negative regulation of striated muscle tissue development	8.882880e-3
GO:0033603	positive regulation of dopamine secretion	8.897897e-3
GO:0007007	inner mitochondrial membrane organization	8.897897e-3
GO:0010712	regulation of collagen metabolic process	9.008609e-3
GO:0007497	posterior midgut development	9.014178e-3
GO:0006957	complement activation, alternative pathway	9.042263e-3
GO:0045660	positive regulation of neutrophil differentiation	9.145958e-3
GO:0010994	free ubiquitin chain polymerization	9.280758e-3
GO:0009452	RNA capping	9.330795e-3
GO:0035303	regulation of dephosphorylation	9.399721e-3
GO:0008156	negative regulation of DNA replication	9.433006e-3
GO:0006744	ubiquinone biosynthetic process	9.586625e-3
GO:0032392	DNA geometric change	9.631809e-3
GO:0070172	positive regulation of tooth mineralization	9.658431e-3
GO:0016246	RNA interference	9.671981e-3
GO:0022614	membrane to membrane docking	9.802093e-3
GO:0021759	globus pallidus development	9.809700e-3
GO:0010631	epithelial cell migration	9.840778e-3
GO:0051324	prophase	9.866877e-3
GO:0032075	positive regulation of nuclease activity	1.016344e-2
GO:0000239	pachytene	1.016344e-2
GO:0016578	histone deubiquitination	1.020552e-2
GO:0051454	intracellular pH elevation	1.026450e-2
GO:0006175	dATP biosynthetic process	1.026450e-2
GO:0090161	Golgi ribbon formation	1.051229e-2
GO:0022417	protein maturation by protein folding	1.051229e-2
GO:0007522	visceral muscle development	1.056093e-2
GO:0008215	spermine metabolic process	1.057935e-2
GO:0016188	synaptic vesicle maturation	1.086331e-2
GO:0051095	regulation of helicase activity	1.086750e-2
GO:0034199	activation of protein kinase A activity	1.112046e-2
GO:2000463	positive regulation of excitatory postsynaptic membrane potential	1.115373e-2
GO:2000249	regulation of actin cytoskeleton reorganization	1.118517e-2
GO:2000064	regulation of cortisol biosynthetic process	1.130677e-2
GO:0010760	negative regulation of macrophage chemotaxis	1.148662e-2
GO:0006338	chromatin remodeling	1.155487e-2
GO:0045128	negative regulation of reciprocal meiotic recombination	1.156826e-2
GO:0006311	meiotic gene conversion	1.156826e-2
GO:0042732	D-xylose metabolic process	1.156826e-2
GO:0034498	early endosome to Golgi transport	1.157351e-2
GO:0048313	Golgi inheritance	1.157351e-2
GO:0002017	regulation of blood volume by renal aldosterone	1.157351e-2
GO:0048627	myoblast development	1.169821e-2
GO:0061301	cerebellum vasculature morphogenesis	1.177296e-2
GO:0048596	embryonic camera-type eye morphogenesis	1.178723e-2
GO:0045416	positive regulation of interleukin-8 biosynthetic process	1.191365e-2
GO:0009165	nucleotide biosynthetic process	1.196830e-2
GO:0045994	positive regulation of translational initiation by iron	1.207326e-2
GO:0002037	negative regulation of L-glutamate transport	1.207326e-2
GO:0043097	pyrimidine nucleoside salvage	1.208008e-2
GO:0090130	tissue migration	1.212618e-2
GO:2000378	negative regulation of reactive oxygen species metabolic process	1.214154e-2
GO:0061196	fungiform papilla development	1.231326e-2
GO:0016569	covalent chromatin modification	1.233728e-2
GO:0016573	histone acetylation	1.241747e-2
GO:0050832	defense response to fungus	1.246800e-2
GO:0015671	oxygen transport	1.253437e-2
GO:0033148	positive regulation of estrogen receptor signaling pathway	1.264888e-2
GO:0031647	regulation of protein stability	1.274610e-2
GO:0006184	GTP catabolic process	1.280852e-2
GO:0001825	blastocyst formation	1.281930e-2
GO:0050821	protein stabilization	1.308132e-2
GO:0051255	spindle midzone assembly	1.314895e-2
GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine	1.314895e-2
GO:0032922	circadian regulation of gene expression	1.324717e-2
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	1.356068e-2
GO:0033128	negative regulation of histone phosphorylation	1.356068e-2
GO:0051303	establishment of chromosome localization	1.368691e-2
GO:0046950	cellular ketone body metabolic process	1.381021e-2
GO:0090140	regulation of mitochondrial fission	1.385382e-2
GO:0048668	collateral sprouting	1.393488e-2
GO:0045426	quinone cofactor biosynthetic process	1.397491e-2
GO:0031943	regulation of glucocorticoid metabolic process	1.405716e-2
GO:0010889	regulation of sequestering of triglyceride	1.420011e-2
GO:0006348	chromatin silencing at telomere	1.420130e-2
GO:2000300	regulation of synaptic vesicle exocytosis	1.445613e-2
GO:0009301	snRNA transcription	1.459082e-2
GO:0048771	tissue remodeling	1.462981e-2
GO:0060620	regulation of cholesterol import	1.466135e-2
GO:0046034	ATP metabolic process	1.508902e-2
GO:0061100	lung neuroendocrine cell differentiation	1.515335e-2
GO:0061102	stomach neuroendocrine cell differentiation	1.515335e-2
GO:0071259	cellular response to magnetism	1.515335e-2
GO:0061104	adrenal chromaffin cell differentiation	1.515335e-2
GO:0061103	carotid body glomus cell differentiation	1.515335e-2
GO:0060165	regulation of timing of subpallium neuron differentiation	1.515335e-2
GO:0060163	subpallium neuron fate commitment	1.515335e-2
GO:0007079	mitotic chromosome movement towards spindle pole	1.515335e-2
GO:0003359	noradrenergic neuron fate commitment	1.515335e-2
GO:0007400	neuroblast fate determination	1.515335e-2
GO:0019448	L-cysteine catabolic process	1.516598e-2
GO:0044336	canonical Wnt receptor signaling pathway involved in negative regulation of apoptosis	1.521927e-2
GO:0045104	intermediate filament cytoskeleton organization	1.524202e-2
GO:0060337	type I interferon-mediated signaling pathway	1.533188e-2
GO:0034619	cellular chaperone-mediated protein complex assembly	1.554514e-2
GO:0070585	protein localization in mitochondrion	1.562394e-2
GO:0006474	N-terminal protein amino acid acetylation	1.570371e-2
GO:0070213	protein auto-ADP-ribosylation	1.573559e-2
GO:0071951	conversion of methionyl-tRNA to N-formyl-methionyl-tRNA	1.581130e-2
GO:0034453	microtubule anchoring	1.584950e-2
GO:0032069	regulation of nuclease activity	1.586084e-2
GO:0030262	apoptotic nuclear change	1.597875e-2
GO:0007143	female meiosis	1.609684e-2
GO:0015669	gas transport	1.621694e-2
GO:0002861	regulation of inflammatory response to antigenic stimulus	1.628224e-2
GO:0033602	negative regulation of dopamine secretion	1.629873e-2
GO:0060816	random inactivation of X chromosome	1.631964e-2
GO:0060220	camera-type eye photoreceptor cell fate commitment	1.631964e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0034382	chylomicron remnant clearance	1.848597e-14
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	3.233617e-12
GO:0010985	negative regulation of lipoprotein particle clearance	5.259956e-12
GO:0010984	regulation of lipoprotein particle clearance	7.568254e-12
GO:0045717	negative regulation of fatty acid biosynthetic process	7.170882e-11
GO:0006538	glutamate catabolic process	7.235135e-11
GO:0045922	negative regulation of fatty acid metabolic process	1.268734e-10
GO:0006184	GTP catabolic process	1.348673e-10
GO:0051005	negative regulation of lipoprotein lipase activity	2.211295e-10
GO:0031536	positive regulation of exit from mitosis	3.611213e-10
GO:0046039	GTP metabolic process	5.637446e-10
GO:0045806	negative regulation of endocytosis	4.693199e-9
GO:0009817	defense response to fungus, incompatible interaction	7.567166e-9
GO:0008608	attachment of spindle microtubules to kinetochore	7.728378e-9
GO:0032488	Cdc42 protein signal transduction	2.078149e-8
GO:0031507	heterochromatin formation	2.493860e-8
GO:0060192	negative regulation of lipase activity	2.564929e-8
GO:0010987	negative regulation of high-density lipoprotein particle clearance	7.317476e-8
GO:0010897	negative regulation of triglyceride catabolic process	7.317476e-8
GO:0010982	regulation of high-density lipoprotein particle clearance	7.759198e-8
GO:0006540	glutamate decarboxylation to succinate	1.002811e-7
GO:0006656	phosphatidylcholine biosynthetic process	1.004044e-7
GO:0051055	negative regulation of lipid biosynthetic process	1.026735e-7
GO:0006139	nucleobase-containing compound metabolic process	1.357280e-7
GO:0042254	ribosome biogenesis	1.551927e-7
GO:0002513	tolerance induction to self antigen	1.655317e-7
GO:0016032	viral reproduction	1.681178e-7
GO:0050995	negative regulation of lipid catabolic process	1.761202e-7
GO:0048261	negative regulation of receptor-mediated endocytosis	1.881593e-7
GO:0034470	ncRNA processing	1.954841e-7
GO:0031508	centromeric heterochromatin formation	2.103748e-7
GO:0010989	negative regulation of low-density lipoprotein particle clearance	2.118948e-7
GO:0007096	regulation of exit from mitosis	2.634607e-7
GO:0016072	rRNA metabolic process	5.087920e-7
GO:0010467	gene expression	5.419118e-7
GO:0034447	very-low-density lipoprotein particle clearance	6.641648e-7
GO:0033239	negative regulation of cellular amine metabolic process	7.808592e-7
GO:0045833	negative regulation of lipid metabolic process	7.868903e-7
GO:0010936	negative regulation of macrophage cytokine production	8.995799e-7
GO:0045046	protein import into peroxisome membrane	1.007109e-6
GO:0002536	respiratory burst involved in inflammatory response	1.106069e-6
GO:0009082	branched chain family amino acid biosynthetic process	1.250807e-6
GO:0010900	negative regulation of phosphatidylcholine catabolic process	1.250807e-6
GO:0050713	negative regulation of interleukin-1 beta secretion	1.262688e-6
GO:0034641	cellular nitrogen compound metabolic process	1.847002e-6
GO:0071173	spindle assembly checkpoint	2.113132e-6
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	2.256808e-6
GO:0031577	spindle checkpoint	3.450252e-6
GO:0044249	cellular biosynthetic process	3.739506e-6
GO:0033700	phospholipid efflux	3.792648e-6
GO:0007406	negative regulation of neuroblast proliferation	4.059509e-6
GO:0090304	nucleic acid metabolic process	4.792990e-6
GO:0006807	nitrogen compound metabolic process	4.915588e-6
GO:0007224	smoothened signaling pathway	5.034668e-6
GO:0016075	rRNA catabolic process	5.911791e-6
GO:0060390	regulation of SMAD protein import into nucleus	7.473644e-6
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	8.237488e-6
GO:0051028	mRNA transport	8.277626e-6
GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	8.564116e-6
GO:0048298	positive regulation of isotype switching to IgA isotypes	8.966023e-6
GO:0050658	RNA transport	9.101505e-6
GO:0000075	cell cycle checkpoint	9.229219e-6
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	9.763007e-6
GO:0044260	cellular macromolecule metabolic process	1.077736e-5
GO:0034660	ncRNA metabolic process	1.277255e-5
GO:0002719	negative regulation of cytokine production involved in immune response	1.364882e-5
GO:0043932	ossification involved in bone remodeling	1.427536e-5
GO:0006536	glutamate metabolic process	1.484701e-5
GO:0051313	attachment of spindle microtubules to chromosome	1.655789e-5
GO:0061136	regulation of proteasomal protein catabolic process	1.714817e-5
GO:0015931	nucleobase-containing compound transport	1.834275e-5
GO:0032375	negative regulation of cholesterol transport	1.845505e-5
GO:0014043	negative regulation of neuron maturation	1.864570e-5
GO:0050711	negative regulation of interleukin-1 secretion	1.897320e-5
GO:0060391	positive regulation of SMAD protein import into nucleus	2.067430e-5
GO:0002701	negative regulation of production of molecular mediator of immune response	2.084370e-5
GO:0070508	cholesterol import	2.242194e-5
GO:0051340	regulation of ligase activity	2.421038e-5
GO:0051788	response to misfolded protein	2.463401e-5
GO:0060433	bronchus development	2.524917e-5
GO:0071843	cellular component biogenesis at cellular level	2.667715e-5
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	2.822483e-5
GO:0046814	virion attachment, binding of host cell surface coreceptor	3.076156e-5
GO:0019064	viral envelope fusion with host membrane	3.076156e-5
GO:0034380	high-density lipoprotein particle assembly	3.098983e-5
GO:0006657	CDP-choline pathway	3.374581e-5
GO:0006364	rRNA processing	3.573988e-5
GO:0050768	negative regulation of neurogenesis	3.604910e-5
GO:0006646	phosphatidylethanolamine biosynthetic process	3.617326e-5
GO:0043537	negative regulation of blood vessel endothelial cell migration	3.667668e-5
GO:0046670	positive regulation of retinal cell programmed cell death	3.791021e-5
GO:0046452	dihydrofolate metabolic process	3.791021e-5
GO:0002525	acute inflammatory response to non-antigenic stimulus	3.791021e-5
GO:0009067	aspartate family amino acid biosynthetic process	3.948572e-5
GO:0009207	purine ribonucleoside triphosphate catabolic process	4.143703e-5
GO:0016557	peroxisome membrane biogenesis	4.279293e-5
GO:0051438	regulation of ubiquitin-protein ligase activity	4.332150e-5
GO:0007212	dopamine receptor signaling pathway	4.628888e-5
GO:0060696	regulation of phospholipid catabolic process	4.894813e-5
GO:2000178	negative regulation of neural precursor cell proliferation	4.953119e-5
GO:0033084	regulation of immature T cell proliferation in thymus	5.254941e-5
GO:0009146	purine nucleoside triphosphate catabolic process	5.495161e-5
GO:0090343	positive regulation of cell aging	5.625086e-5
GO:0032465	regulation of cytokinesis	5.757687e-5
GO:0045541	negative regulation of cholesterol biosynthetic process	6.537274e-5
GO:0006403	RNA localization	6.785264e-5
GO:0060621	negative regulation of cholesterol import	6.872134e-5
GO:0033344	cholesterol efflux	7.134583e-5
GO:0009065	glutamine family amino acid catabolic process	7.193348e-5
GO:0046474	glycerophospholipid biosynthetic process	7.549699e-5
GO:0018243	protein O-linked glycosylation via threonine	7.554333e-5
GO:0018242	protein O-linked glycosylation via serine	7.554333e-5
GO:0022613	ribonucleoprotein complex biogenesis	7.748324e-5
GO:0008652	cellular amino acid biosynthetic process	8.378917e-5
GO:0071156	regulation of cell cycle arrest	8.862150e-5
GO:0019550	glutamate catabolic process to aspartate	9.019161e-5
GO:0019551	glutamate catabolic process to 2-oxoglutarate	9.019161e-5
GO:0006533	aspartate catabolic process	9.019161e-5
GO:0006532	aspartate biosynthetic process	9.019161e-5
GO:0008033	tRNA processing	9.189310e-5
GO:0035307	positive regulation of protein dephosphorylation	9.374132e-5
GO:0021539	subthalamus development	9.892275e-5
GO:0009143	nucleoside triphosphate catabolic process	1.006751e-4
GO:0044237	cellular metabolic process	1.102486e-4
GO:0035306	positive regulation of dephosphorylation	1.114634e-4
GO:0051926	negative regulation of calcium ion transport	1.260440e-4
GO:0051351	positive regulation of ligase activity	1.260440e-4
GO:0009261	ribonucleotide catabolic process	1.270279e-4
GO:0071712	ER-associated misfolded protein catabolic process	1.273191e-4
GO:0032915	positive regulation of transforming growth factor beta2 production	1.273191e-4
GO:0090307	spindle assembly involved in mitosis	1.313188e-4
GO:0043163	cell envelope organization	1.314170e-4
GO:0009154	purine ribonucleotide catabolic process	1.318549e-4
GO:0033083	regulation of immature T cell proliferation	1.323971e-4
GO:0045862	positive regulation of proteolysis	1.365428e-4
GO:0019049	evasion of host defenses by virus	1.408973e-4
GO:0070286	axonemal dynein complex assembly	1.454773e-4
GO:0033088	negative regulation of immature T cell proliferation in thymus	1.454773e-4
GO:0060439	trachea morphogenesis	1.523933e-4
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling	1.566777e-4
GO:0048259	regulation of receptor-mediated endocytosis	1.724443e-4
GO:0018206	peptidyl-methionine modification	1.748765e-4
GO:0045839	negative regulation of mitosis	1.854749e-4
GO:0051443	positive regulation of ubiquitin-protein ligase activity	1.900240e-4
GO:0051004	regulation of lipoprotein lipase activity	1.912076e-4
GO:0045123	cellular extravasation	1.918139e-4
GO:0043623	cellular protein complex assembly	1.956880e-4
GO:0050765	negative regulation of phagocytosis	1.987574e-4
GO:0016567	protein ubiquitination	1.991419e-4
GO:0006868	glutamine transport	2.017399e-4
GO:0060438	trachea development	2.062499e-4
GO:0021871	forebrain regionalization	2.104226e-4
GO:0016070	RNA metabolic process	2.115584e-4
GO:0060620	regulation of cholesterol import	2.120782e-4
GO:0048368	lateral mesoderm development	2.120782e-4
GO:0051322	anaphase	2.120782e-4
GO:0045210	FasL biosynthetic process	2.298554e-4
GO:0001935	endothelial cell proliferation	2.307231e-4
GO:0043508	negative regulation of JUN kinase activity	2.407970e-4
GO:0018202	peptidyl-histidine modification	2.463070e-4
GO:0009199	ribonucleoside triphosphate metabolic process	2.466306e-4
GO:0008635	activation of caspase activity by cytochrome c	2.560087e-4
GO:0000733	DNA strand renaturation	2.744996e-4
GO:0033599	regulation of mammary gland epithelial cell proliferation	2.759721e-4
GO:0006713	glucocorticoid catabolic process	2.796881e-4
GO:0071636	positive regulation of transforming growth factor beta production	2.866025e-4
GO:0070979	protein K11-linked ubiquitination	2.872406e-4
GO:0000087	M phase of mitotic cell cycle	2.888051e-4
GO:0021933	radial glia guided migration of cerebellar granule cell	2.904389e-4
GO:0051315	attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation	2.914590e-4
GO:0034645	cellular macromolecule biosynthetic process	2.948068e-4
GO:0031055	chromatin remodeling at centromere	3.074165e-4
GO:0009205	purine ribonucleoside triphosphate metabolic process	3.120679e-4
GO:0021997	neural plate axis specification	3.220308e-4
GO:0042256	mature ribosome assembly	3.234183e-4
GO:0006531	aspartate metabolic process	3.234183e-4
GO:0006654	phosphatidic acid biosynthetic process	3.370696e-4
GO:0009309	amine biosynthetic process	3.421775e-4
GO:0070193	synaptonemal complex organization	3.450585e-4
GO:0048596	embryonic camera-type eye morphogenesis	3.507945e-4
GO:0045599	negative regulation of fat cell differentiation	3.577222e-4
GO:0021532	neural tube patterning	3.663559e-4
GO:0045778	positive regulation of ossification	3.730191e-4
GO:0051099	positive regulation of binding	3.730271e-4
GO:0008054	cyclin catabolic process	3.776015e-4
GO:0030202	heparin metabolic process	3.883739e-4
GO:0032446	protein modification by small protein conjugation	3.945558e-4
GO:0035024	negative regulation of Rho protein signal transduction	4.306562e-4
GO:0001573	ganglioside metabolic process	4.383864e-4
GO:0042136	neurotransmitter biosynthetic process	4.483176e-4
GO:0031396	regulation of protein ubiquitination	4.505355e-4
GO:0061072	iris morphogenesis	4.553452e-4
GO:0072205	metanephric collecting duct development	4.608999e-4
GO:0006999	nuclear pore organization	4.628643e-4
GO:0006106	fumarate metabolic process	4.700786e-4
GO:0000060	protein import into nucleus, translocation	4.735682e-4
GO:0031398	positive regulation of protein ubiquitination	4.808518e-4
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	4.876302e-4
GO:0060744	mammary gland branching involved in thelarche	4.977088e-4
GO:0035066	positive regulation of histone acetylation	5.009856e-4
GO:0006913	nucleocytoplasmic transport	5.177998e-4
GO:0042360	vitamin E metabolic process	5.375284e-4
GO:0051169	nuclear transport	5.399260e-4
GO:0006457	protein folding	5.405305e-4
GO:0001755	neural crest cell migration	5.592899e-4
GO:0031575	mitotic cell cycle G1/S transition checkpoint	5.713968e-4
GO:0031076	embryonic camera-type eye development	5.824145e-4
GO:0071218	cellular response to misfolded protein	6.010038e-4
GO:0007067	mitosis	6.043014e-4
GO:0010721	negative regulation of cell development	6.247437e-4
GO:0060461	right lung morphogenesis	6.477900e-4
GO:0090131	mesenchyme migration	6.477900e-4
GO:0060446	branching involved in open tracheal system development	6.477900e-4
GO:0048613	embryonic ectodermal digestive tract morphogenesis	6.477900e-4
GO:0048371	lateral mesodermal cell differentiation	6.477900e-4
GO:0014822	detection of wounding	6.477900e-4
GO:0051168	nuclear export	6.529002e-4
GO:0042772	DNA damage response, signal transduction resulting in transcription	6.565692e-4
GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	6.583811e-4
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	6.696617e-4
GO:0007093	mitotic cell cycle checkpoint	6.809059e-4
GO:0035645	enteric smooth muscle cell differentiation	7.180126e-4
GO:0030719	P granule organization	7.180126e-4
GO:0000395	nuclear mRNA 5'-splice site recognition	7.180126e-4
GO:0007497	posterior midgut development	7.180126e-4
GO:0007052	mitotic spindle organization	7.729056e-4
GO:0060364	frontal suture morphogenesis	7.769704e-4
GO:0006195	purine nucleotide catabolic process	7.874904e-4
GO:0008354	germ cell migration	7.885491e-4
GO:0009144	purine nucleoside triphosphate metabolic process	8.624828e-4
GO:0009259	ribonucleotide metabolic process	8.635211e-4
GO:0045629	negative regulation of T-helper 2 cell differentiation	8.657730e-4
GO:0031365	N-terminal protein amino acid modification	8.747924e-4
GO:0006555	methionine metabolic process	8.747924e-4
GO:0060020	Bergmann glial cell differentiation	8.802816e-4
GO:0060535	trachea cartilage morphogenesis	8.828940e-4
GO:0009141	nucleoside triphosphate metabolic process	9.274236e-4
GO:0046639	negative regulation of alpha-beta T cell differentiation	9.379588e-4
GO:0033238	regulation of cellular amine metabolic process	9.500873e-4
GO:0008208	C21-steroid hormone catabolic process	9.538797e-4
GO:0035315	hair cell differentiation	9.538797e-4
GO:0006611	protein export from nucleus	9.576130e-4
GO:0007569	cell aging	9.929936e-4
GO:0021546	rhombomere development	1.014160e-3
GO:0051693	actin filament capping	1.030220e-3
GO:0072061	inner medullary collecting duct development	1.031009e-3
GO:0072060	outer medullary collecting duct development	1.031009e-3
GO:0016332	establishment or maintenance of polarity of embryonic epithelium	1.031009e-3
GO:0006664	glycolipid metabolic process	1.043909e-3
GO:0010994	free ubiquitin chain polymerization	1.085738e-3
GO:0032092	positive regulation of protein binding	1.087134e-3
GO:0071841	cellular component organization or biogenesis at cellular level	1.088730e-3
GO:0001555	oocyte growth	1.094409e-3
GO:0030382	sperm mitochondrion organization	1.094409e-3
GO:0021978	telencephalon regionalization	1.095421e-3
GO:0044238	primary metabolic process	1.104885e-3
GO:0022415	viral reproductive process	1.130044e-3
GO:0006344	maintenance of chromatin silencing	1.220499e-3
GO:0006687	glycosphingolipid metabolic process	1.239155e-3
GO:0010596	negative regulation of endothelial cell migration	1.277053e-3
GO:0042443	phenylethylamine metabolic process	1.300554e-3
GO:0018125	peptidyl-cysteine methylation	1.300554e-3
GO:0002418	immune response to tumor cell	1.300554e-3
GO:0051225	spindle assembly	1.308427e-3
GO:0060534	trachea cartilage development	1.309883e-3
GO:0043170	macromolecule metabolic process	1.332553e-3
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.339418e-3
GO:0090403	oxidative stress-induced premature senescence	1.339595e-3
GO:0007094	mitotic cell cycle spindle assembly checkpoint	1.339595e-3
GO:0051016	barbed-end actin filament capping	1.339595e-3
GO:0060033	anatomical structure regression	1.414009e-3
GO:0070925	organelle assembly	1.414260e-3
GO:0060458	right lung development	1.447239e-3
GO:0006398	histone mRNA 3'-end processing	1.447239e-3
GO:0009059	macromolecule biosynthetic process	1.465460e-3
GO:0009058	biosynthetic process	1.467644e-3
GO:0009166	nucleotide catabolic process	1.487705e-3
GO:0006780	uroporphyrinogen III biosynthetic process	1.504791e-3
GO:0035582	negative regulation of BMP signaling pathway by extracellular sequestering of BMP	1.504791e-3
GO:0017196	N-terminal peptidyl-methionine acetylation	1.504791e-3
GO:0090209	negative regulation of triglyceride metabolic process	1.520039e-3
GO:0009086	methionine biosynthetic process	1.520039e-3
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	1.520039e-3
GO:0007130	synaptonemal complex assembly	1.536229e-3
GO:0006396	RNA processing	1.547228e-3
GO:0007435	salivary gland morphogenesis	1.547805e-3
GO:0008156	negative regulation of DNA replication	1.661590e-3
GO:0042866	pyruvate biosynthetic process	1.661727e-3
GO:0071174	mitotic cell cycle spindle checkpoint	1.671392e-3
GO:0035426	extracellular matrix-cell signaling	1.715787e-3
GO:0016574	histone ubiquitination	1.721744e-3
GO:0030259	lipid glycosylation	1.780492e-3
GO:0009150	purine ribonucleotide metabolic process	1.795485e-3
GO:0031570	DNA integrity checkpoint	1.801284e-3
GO:0032369	negative regulation of lipid transport	1.812841e-3
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	1.817146e-3
GO:0014032	neural crest cell development	1.884203e-3
GO:0072523	purine-containing compound catabolic process	1.904573e-3
GO:0060136	embryonic process involved in female pregnancy	1.907294e-3
GO:0046394	carboxylic acid biosynthetic process	1.923118e-3
GO:0060363	cranial suture morphogenesis	1.962674e-3
GO:0010896	regulation of triglyceride catabolic process	1.962674e-3
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.990105e-3
GO:0016098	monoterpenoid metabolic process	1.990105e-3
GO:0031427	response to methotrexate	1.990105e-3
GO:0060482	lobar bronchus development	2.012461e-3
GO:0010310	regulation of hydrogen peroxide metabolic process	2.012461e-3
GO:2000774	positive regulation of cellular senescence	2.038137e-3
GO:0035986	senescence-associated heterochromatin focus formation	2.038137e-3
GO:0090402	oncogene-induced senescence	2.038137e-3
GO:0001829	trophectodermal cell differentiation	2.070165e-3
GO:0006302	double-strand break repair	2.081020e-3
GO:0046470	phosphatidylcholine metabolic process	2.095188e-3
GO:0042304	regulation of fatty acid biosynthetic process	2.110922e-3
GO:0006351	transcription, DNA-dependent	2.133637e-3
GO:0070723	response to cholesterol	2.154950e-3
GO:0090311	regulation of protein deacetylation	2.178615e-3
GO:0070370	cellular heat acclimation	2.224992e-3
GO:0045685	regulation of glial cell differentiation	2.229675e-3
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	2.252922e-3
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	2.252922e-3
GO:0043316	cytotoxic T cell degranulation	2.255187e-3
GO:0000279	M phase	2.255905e-3
GO:0043535	regulation of blood vessel endothelial cell migration	2.335053e-3
GO:0021903	rostrocaudal neural tube patterning	2.371548e-3
GO:0006368	transcription elongation from RNA polymerase II promoter	2.387780e-3
GO:0060686	negative regulation of prostatic bud formation	2.387780e-3
GO:0044091	membrane biogenesis	2.451744e-3
GO:0045077	negative regulation of interferon-gamma biosynthetic process	2.454688e-3
GO:0018199	peptidyl-glutamine modification	2.454688e-3
GO:0000077	DNA damage checkpoint	2.454729e-3
GO:0030260	entry into host cell	2.478230e-3
GO:2000045	regulation of G1/S transition of mitotic cell cycle	2.504301e-3
GO:0007431	salivary gland development	2.526352e-3
GO:0010458	exit from mitosis	2.542224e-3
GO:0048312	intracellular distribution of mitochondria	2.544074e-3
GO:0046599	regulation of centriole replication	2.544074e-3
GO:0045581	negative regulation of T cell differentiation	2.562163e-3
GO:0032774	RNA biosynthetic process	2.590673e-3
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	2.593088e-3
GO:0090312	positive regulation of protein deacetylation	2.603565e-3
GO:0090399	replicative senescence	2.608806e-3
GO:0009064	glutamine family amino acid metabolic process	2.772971e-3
GO:0060445	branching involved in salivary gland morphogenesis	2.906555e-3
GO:0072012	glomerulus vasculature development	2.919121e-3
GO:0031063	regulation of histone deacetylation	2.941533e-3
GO:0034655	nucleobase-containing compound catabolic process	2.948778e-3
GO:0008334	histone mRNA metabolic process	2.969027e-3
GO:0071779	G1/S transition checkpoint	3.015940e-3
GO:0042130	negative regulation of T cell proliferation	3.096177e-3
GO:0006975	DNA damage induced protein phosphorylation	3.116308e-3
GO:0072044	collecting duct development	3.117744e-3
GO:0010950	positive regulation of endopeptidase activity	3.126073e-3
GO:0000090	mitotic anaphase	3.126073e-3
GO:0032287	peripheral nervous system myelin maintenance	3.185246e-3
GO:0072104	glomerular capillary formation	3.213997e-3
GO:0030917	midbrain-hindbrain boundary development	3.282241e-3
GO:0014031	mesenchymal cell development	3.284984e-3
GO:0046939	nucleotide phosphorylation	3.349860e-3
GO:0014041	regulation of neuron maturation	3.411571e-3
GO:0072428	signal transduction involved in intra-S DNA damage checkpoint	3.496219e-3
GO:0002357	defense response to tumor cell	3.496219e-3
GO:0021930	cerebellar granule cell precursor proliferation	3.515413e-3
GO:0071394	cellular response to testosterone stimulus	3.515413e-3
GO:0021660	rhombomere 3 formation	3.515413e-3
GO:0021666	rhombomere 5 formation	3.515413e-3
GO:0021555	midbrain-hindbrain boundary morphogenesis	3.515653e-3
GO:0034661	ncRNA catabolic process	3.531426e-3
GO:0051150	regulation of smooth muscle cell differentiation	3.563164e-3
GO:0031065	positive regulation of histone deacetylation	3.607641e-3
GO:0009303	rRNA transcription	3.607641e-3
GO:0048048	embryonic eye morphogenesis	3.640774e-3
GO:0006642	triglyceride mobilization	3.655150e-3
GO:0046700	heterocycle catabolic process	3.671736e-3
GO:0045620	negative regulation of lymphocyte differentiation	3.693916e-3
GO:0060751	branch elongation involved in mammary gland duct branching	3.722775e-3
GO:0014033	neural crest cell differentiation	3.722794e-3
GO:0001777	T cell homeostatic proliferation	3.727466e-3
GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity	3.757649e-3
GO:0006601	creatine biosynthetic process	3.782652e-3
GO:0046502	uroporphyrinogen III metabolic process	3.782652e-3
GO:0071422	succinate transmembrane transport	3.782652e-3
GO:0033590	response to cobalamin	3.782652e-3
GO:0030501	positive regulation of bone mineralization	3.788130e-3
GO:0021993	initiation of neural tube closure	3.825101e-3
GO:0046718	entry of virus into host cell	3.882239e-3
GO:0010498	proteasomal protein catabolic process	3.895499e-3
GO:0034381	plasma lipoprotein particle clearance	3.928110e-3
GO:0060389	pathway-restricted SMAD protein phosphorylation	3.993608e-3
GO:0001569	patterning of blood vessels	3.999340e-3
GO:0006281	DNA repair	4.003435e-3
GO:0090342	regulation of cell aging	4.021892e-3
GO:0032509	endosome transport via multivesicular body sorting pathway	4.220290e-3
GO:0032467	positive regulation of cytokinesis	4.279761e-3
GO:0032367	intracellular cholesterol transport	4.293897e-3
GO:0010824	regulation of centrosome duplication	4.418187e-3
GO:0002739	regulation of cytokine secretion involved in immune response	4.420838e-3
GO:0010873	positive regulation of cholesterol esterification	4.558745e-3
GO:0046580	negative regulation of Ras protein signal transduction	4.631299e-3
GO:0048285	organelle fission	4.713742e-3
GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation	4.760215e-3
GO:0060644	mammary gland epithelial cell differentiation	4.769557e-3
GO:0021520	spinal cord motor neuron cell fate specification	4.820352e-3
GO:0072040	negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis	4.867778e-3
GO:0070169	positive regulation of biomineral tissue development	4.946040e-3
GO:0034377	plasma lipoprotein particle assembly	4.984335e-3
GO:0070534	protein K63-linked ubiquitination	4.986411e-3
GO:0051129	negative regulation of cellular component organization	5.008777e-3
GO:0003350	pulmonary myocardium development	5.098384e-3
GO:0090273	regulation of somatostatin secretion	5.100461e-3
GO:0090075	relaxation of muscle	5.299586e-3
GO:0072203	cell proliferation involved in metanephros development	5.357952e-3
GO:0050901	leukocyte tethering or rolling	5.357952e-3
GO:0070179	D-serine biosynthetic process	5.395122e-3
GO:0035674	tricarboxylic acid transmembrane transport	5.395122e-3
GO:0046636	negative regulation of alpha-beta T cell activation	5.533867e-3
GO:0071577	zinc ion transmembrane transport	5.547742e-3
GO:0019048	virus-host interaction	5.553469e-3
GO:0032785	negative regulation of transcription elongation, DNA-dependent	5.604528e-3
GO:0072136	metanephric mesenchymal cell proliferation involved in metanephros development	5.606815e-3
GO:0048597	post-embryonic camera-type eye morphogenesis	5.606815e-3
GO:0042713	sperm ejaculation	5.606815e-3
GO:0045017	glycerolipid biosynthetic process	5.638756e-3
GO:0019059	initiation of viral infection	5.694988e-3
GO:0048014	Tie receptor signaling pathway	5.694988e-3
GO:0009083	branched chain family amino acid catabolic process	5.748426e-3
GO:0051058	negative regulation of small GTPase mediated signal transduction	5.805023e-3
GO:0048352	paraxial mesoderm structural organization	5.807656e-3
GO:0032805	positive regulation of low-density lipoprotein particle receptor catabolic process	5.807656e-3
GO:0021998	neural plate mediolateral regionalization	5.807656e-3
GO:0021797	forebrain anterior/posterior pattern specification	5.867124e-3
GO:0030071	regulation of mitotic metaphase/anaphase transition	5.890122e-3
GO:0021658	rhombomere 3 morphogenesis	5.986756e-3
GO:0021568	rhombomere 2 development	5.986756e-3
GO:0045793	positive regulation of cell size	6.021143e-3
GO:0051152	positive regulation of smooth muscle cell differentiation	6.042251e-3
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	6.073313e-3
GO:0030835	negative regulation of actin filament depolymerization	6.073466e-3
GO:0000281	cytokinesis after mitosis	6.086088e-3
GO:0048762	mesenchymal cell differentiation	6.140958e-3
GO:0007521	muscle cell fate determination	6.336613e-3
GO:0046784	intronless viral mRNA export from host nucleus	6.414535e-3
GO:0030834	regulation of actin filament depolymerization	6.635557e-3
GO:0051865	protein autoubiquitination	6.694843e-3
GO:0060485	mesenchyme development	6.853904e-3
GO:0006354	transcription elongation, DNA-dependent	6.999495e-3
GO:0048311	mitochondrion distribution	7.074224e-3
GO:0009396	folic acid-containing compound biosynthetic process	7.074224e-3
GO:0055118	negative regulation of cardiac muscle contraction	7.178397e-3
GO:0043538	regulation of actin phosphorylation	7.314352e-3
GO:0035865	cellular response to potassium ion	7.314352e-3
GO:2000299	negative regulation of Rho-dependent protein serine/threonine kinase activity	7.314352e-3
GO:0090212	negative regulation of establishment of blood-brain barrier	7.314352e-3
GO:0055107	Golgi to secretory granule transport	7.314352e-3
GO:0016140	O-glycoside metabolic process	7.314352e-3
GO:0006256	UDP catabolic process	7.314352e-3
GO:0009236	cobalamin biosynthetic process	7.314352e-3
GO:0015969	guanosine tetraphosphate metabolic process	7.314352e-3
GO:0035750	protein localization to myelin sheath abaxonal region	7.314352e-3
GO:0034651	cortisol biosynthetic process	7.314352e-3
GO:0015804	neutral amino acid transport	7.339535e-3
GO:0032332	positive regulation of chondrocyte differentiation	7.439380e-3
GO:0006515	misfolded or incompletely synthesized protein catabolic process	7.457190e-3
GO:0042637	catagen	7.457190e-3
GO:0035195	gene silencing by miRNA	7.566956e-3
GO:0032916	positive regulation of transforming growth factor beta3 production	7.601355e-3
GO:0001880	Mullerian duct regression	7.618806e-3
GO:0072054	renal outer medulla development	7.618806e-3
GO:0006399	tRNA metabolic process	7.623634e-3
GO:0070509	calcium ion import	7.683871e-3
GO:0007089	traversing start control point of mitotic cell cycle	7.737204e-3
GO:2000173	negative regulation of branching morphogenesis of a nerve	7.737204e-3
GO:0014842	regulation of satellite cell proliferation	7.737204e-3
GO:0048213	Golgi vesicle prefusion complex stabilization	8.028652e-3
GO:0002542	Factor XII activation	8.028652e-3
GO:0010793	regulation of mRNA export from nucleus	8.028652e-3
GO:0051170	nuclear import	8.048158e-3
GO:0034375	high-density lipoprotein particle remodeling	8.101189e-3
GO:0061311	cell surface receptor linked signaling pathway involved in heart development	8.363616e-3
GO:0048562	embryonic organ morphogenesis	8.414963e-3
GO:0007398	ectoderm development	8.415730e-3
GO:0050868	negative regulation of T cell activation	8.419184e-3
GO:0002679	respiratory burst involved in defense response	8.449937e-3
GO:0060659	nipple sheath formation	8.621159e-3
GO:0061301	cerebellum vasculature morphogenesis	8.621159e-3
GO:0060649	mammary gland bud elongation	8.621159e-3
GO:0055089	fatty acid homeostasis	8.625766e-3
GO:0034508	centromere complex assembly	8.625766e-3
GO:0002740	negative regulation of cytokine secretion involved in immune response	8.749853e-3
GO:0032218	riboflavin transport	8.834859e-3
GO:0043248	proteasome assembly	8.942773e-3
GO:0042482	positive regulation of odontogenesis	8.942773e-3
GO:0007028	cytoplasm organization	8.942773e-3
GO:0072053	renal inner medulla development	9.059169e-3
GO:0043366	beta selection	9.059169e-3
GO:0048050	post-embryonic eye morphogenesis	9.059169e-3
GO:0001574	ganglioside biosynthetic process	9.306674e-3
GO:0007422	peripheral nervous system development	9.310250e-3
GO:0021932	hindbrain radial glia guided cell migration	9.355669e-3
GO:0048484	enteric nervous system development	9.392336e-3