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MCL coexpression mm9:1555: Difference between revisions

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|gostat_on_MCL_coexpression=GO:0017015;regulation of transforming growth factor beta receptor signaling pathway;0.00657426176518929;27528!GO:0007179;transforming growth factor beta receptor signaling pathway;0.0151208020599354;27528!GO:0007178;transmembrane receptor protein serine/threonine kinase signaling pathway;0.0173122226483318;27528!GO:0007167;enzyme linked receptor protein signaling pathway;0.0435216128855531;27528!GO:0009966;regulation of signal transduction;0.0435216128855531;27528!
|gostat_on_MCL_coexpression=GO:0017015;regulation of transforming growth factor beta receptor signaling pathway;0.00657426176518929;27528!GO:0007179;transforming growth factor beta receptor signaling pathway;0.0151208020599354;27528!GO:0007178;transmembrane receptor protein serine/threonine kinase signaling pathway;0.0173122226483318;27528!GO:0007167;enzyme linked receptor protein signaling pathway;0.0435216128855531;27528!GO:0009966;regulation of signal transduction;0.0435216128855531;27528!
|ontology_enrichment_celltype=CL:0000117!3.02e-09!23;CL:0000337!3.02e-09!23;CL:0000540!5.05e-09!33;CL:0000047!5.05e-09!33;CL:0000031!5.05e-09!33;CL:0000404!5.05e-09!33;CL:0000393!9.64e-07!39;CL:0000211!9.64e-07!39
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0000468!1.68e-10!333;UBERON:0010314!1.59e-09!92;UBERON:0002346!2.27e-08!64;UBERON:0003075!2.27e-08!64;UBERON:0007284!2.27e-08!64;UBERON:0010371!4.04e-08!73;UBERON:0000922!8.50e-08!320;UBERON:0001017!1.51e-07!73;UBERON:0004121!2.25e-07!95;UBERON:0000924!2.25e-07!95;UBERON:0006601!2.25e-07!95
}}
}}

Revision as of 17:04, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr11:119089775..119089818,-p1@Tbc1d16
Mm9::chr18:33622192..33622198,-p@chr18:33622192..33622198
-
Mm9::chr18:33623069..33623097,-p1@D0H4S114
Mm9::chr18:33623104..33623127,-p4@D0H4S114
Mm9::chr7:52410080..52410104,+p@chr7:52410080..52410104
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0017015regulation of transforming growth factor beta receptor signaling pathway0.00657426176518929
GO:0007179transforming growth factor beta receptor signaling pathway0.0151208020599354
GO:0007178transmembrane receptor protein serine/threonine kinase signaling pathway0.0173122226483318
GO:0007167enzyme linked receptor protein signaling pathway0.0435216128855531
GO:0009966regulation of signal transduction0.0435216128855531



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
CNS neuron (sensu Vertebrata)3.02e-0923
neuroblast (sensu Vertebrata)3.02e-0923
neuron5.05e-0933
neuronal stem cell5.05e-0933
neuroblast5.05e-0933
electrically signaling cell5.05e-0933
electrically responsive cell9.64e-0739
electrically active cell9.64e-0739


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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