MCL coexpression mm9:704

Phase1 CAGE Peaks

	Short description
Mm9::chr11:121296262..121296301,+	p1@Fn3k
Mm9::chr11:31770901..31770923,+	p1@Cpeb4
Mm9::chr11:61770282..61770293,+	p3@Specc1
Mm9::chr11:74433096..74433145,+	p1@E130309D14Rik
Mm9::chr16:58670619..58670668,+	p@chr16:58670619..58670668 +
Mm9::chr2:84574207..84574264,+	p1@Ypel4
Mm9::chr2:84578292..84578295,+	p@chr2:84578292..84578295 +
Mm9::chr6:72047555..72047624,+	p1@St3gal5
Mm9::chr8:63433523..63433587,-	p2@Clcn3
Mm9::chr9:44096214..44096236,-	p3@Abcg4

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0030389	fructosamine metabolic process	0.0241056264723607
GO:0030387	fructosamine-3-kinase activity	0.0241056264723607
GO:0004109	coproporphyrinogen oxidase activity	0.032134671976103

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

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Cell Type

Ontology term	p-value	n
neuron	3.48e-07	33
neuronal stem cell	3.48e-07	33
neuroblast	3.48e-07	33
electrically signaling cell	3.48e-07	33

Uber Anatomy

Ontology term	p-value	n
central nervous system	4.30e-18	73
nervous system	2.28e-17	75
neurectoderm	1.01e-16	64
neural plate	1.01e-16	64
presumptive neural plate	1.01e-16	64
regional part of nervous system	1.41e-16	54
structure with developmental contribution from neural crest	2.32e-16	92
neural tube	1.92e-15	52
neural rod	1.92e-15	52
future spinal cord	1.92e-15	52
neural keel	1.92e-15	52
ectoderm-derived structure	6.47e-15	95
ectoderm	6.47e-15	95
presumptive ectoderm	6.47e-15	95
ecto-epithelium	1.26e-13	73
brain	2.65e-13	47
future brain	2.65e-13	47
regional part of brain	7.31e-13	46
pre-chordal neural plate	9.11e-12	49
gray matter	2.46e-11	34
anterior neural tube	6.51e-11	40
tube	9.37e-11	114
regional part of forebrain	2.53e-10	39
forebrain	2.53e-10	39
future forebrain	2.53e-10	39
anatomical conduit	3.38e-10	122
brain grey matter	1.80e-09	29
regional part of telencephalon	1.80e-09	29
telencephalon	1.80e-09	29
multi-cellular organism	1.05e-07	333
cerebral cortex	6.29e-07	21
cerebral hemisphere	6.29e-07	21
pallium	6.29e-07	21

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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