MCL coexpression mm9:2170

Phase1 CAGE Peaks

	Short description
Mm9::chr16:19883954..19883965,-	p4@A930003A15Rik
Mm9::chr17:25257732..25257748,+	p1@Ptx4
Mm9::chr3:89876563..89876579,+	p3@Tpm3
Mm9::chr5:137165168..137165170,+	p@chr5:137165168..137165170 +

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0032154	cleavage furrow	0.00300407238992677
GO:0002102	podosome	0.00300407238992677
GO:0005862	muscle thin filament tropomyosin	0.00300407238992677
GO:0032153	cell division site	0.00300407238992677
GO:0032155	cell division site part	0.00300407238992677
GO:0031941	filamentous actin	0.00300407238992677
GO:0030426	growth cone	0.00437736262532187
GO:0030427	site of polarized growth	0.00437736262532187
GO:0005865	striated muscle thin filament	0.00437736262532187
GO:0030863	cortical cytoskeleton	0.00437736262532187
GO:0005884	actin filament	0.00538392194558304
GO:0044448	cell cortex part	0.00600814477985354
GO:0006937	regulation of muscle contraction	0.00653633333192858
GO:0005938	cell cortex	0.00864437157101377
GO:0030017	sarcomere	0.0106859146441681
GO:0044449	contractile fiber part	0.0106859146441681
GO:0030016	myofibril	0.0106859146441681
GO:0043292	contractile fiber	0.0106859146441681
GO:0003012	muscle system process	0.0106859146441681
GO:0006936	muscle contraction	0.0106859146441681
GO:0043005	neuron projection	0.0142233631523063
GO:0015629	actin cytoskeleton	0.0222379384708865
GO:0003779	actin binding	0.0270926280135011
GO:0051239	regulation of multicellular organismal process	0.0298261472999872
GO:0008092	cytoskeletal protein binding	0.0344009203966471
GO:0042995	cell projection	0.0360488686791213
GO:0044430	cytoskeletal part	0.0495910362781562

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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