MCL coexpression mm9:728

Phase1 CAGE Peaks

	Short description
Mm9::chr13:74945361..74945437,-	p1@Cast
Mm9::chr18:23912236..23912260,+	p5@Mapre2
Mm9::chr19:5560600..5560617,-	p1@Ovol1
Mm9::chr2:24223085..24223140,+	p3@Psd4
Mm9::chr4:55545337..55545357,-	p1@Klf4
Mm9::chr5:75098978..75098991,-	p4@Lnx1
Mm9::chr9:76414899..76414930,-	p1@Fam83b
Mm9::chr9:76414933..76414938,-	p2@Fam83b
Mm9::chrX:109812273..109812298,-	p2@Pof1b
Mm9::chrX:7318414..7318447,-	p2@Ccdc120

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0030161	calpain inhibitor activity	0.0405925320326153
GO:0042787	protein ubiquitination during ubiquitin-dependent protein catabolic process	0.0405925320326153
GO:0000239	pachytene	0.0405925320326153
GO:0030163	protein catabolic process	0.0405925320326153
GO:0045892	negative regulation of transcription, DNA-dependent	0.0405925320326153
GO:0043285	biopolymer catabolic process	0.0405925320326153
GO:0000279	M phase	0.0405925320326153
GO:0016481	negative regulation of transcription	0.0405925320326153
GO:0007128	meiotic prophase I	0.0405925320326153
GO:0051324	prophase	0.0405925320326153
GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.0405925320326153
GO:0032011	ARF protein signal transduction	0.0405925320326153
GO:0005086	ARF guanyl-nucleotide exchange factor activity	0.0405925320326153
GO:0030165	PDZ domain binding	0.0405925320326153
GO:0032012	regulation of ARF protein signal transduction	0.0405925320326153
GO:0022403	cell cycle phase	0.0405925320326153
GO:0009057	macromolecule catabolic process	0.0420435605551518
GO:0031324	negative regulation of cellular metabolic process	0.0420435605551518
GO:0009892	negative regulation of metabolic process	0.0491480804908414
GO:0008092	cytoskeletal protein binding	0.0491480804908414

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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