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Coexpression cluster:C280: Difference between revisions

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|full_id=C280_Mast_Natural_CD19_CD8_Eosinophils_CD34_CD4
|full_id=C280_Mast_Natural_CD19_CD8_Eosinophils_CD34_CD4
|id=C280
|id=C280
|ontology_enrichment_celltype=CL:0000037!7.05e-45!172;CL:0000566!7.05e-45!172;CL:0000738!2.04e-44!140;CL:0000988!4.70e-41!182;CL:0002032!4.78e-41!165;CL:0000837!4.78e-41!165;CL:0002031!4.02e-35!124;CL:0002087!9.96e-34!119;CL:0002057!1.49e-23!42;CL:0000860!1.27e-21!45;CL:0000542!2.46e-20!53;CL:0000051!2.46e-20!53;CL:0000763!3.71e-20!112;CL:0000049!3.71e-20!112;CL:0000838!4.25e-20!52;CL:0000766!1.36e-18!76;CL:0000557!6.71e-16!71;CL:0000839!2.61e-14!70;CL:0002009!2.63e-13!65;CL:0002194!2.13e-12!63;CL:0000576!2.13e-12!63;CL:0000040!2.13e-12!63;CL:0000559!2.13e-12!63;CL:0000084!9.75e-11!25;CL:0000827!9.75e-11!25;CL:0000791!1.34e-10!18;CL:0000789!1.34e-10!18;CL:0002420!1.34e-10!18;CL:0002419!1.34e-10!18;CL:0000790!1.34e-10!18;CL:0000945!9.11e-09!24;CL:0000826!9.11e-09!24;CL:0000236!1.98e-07!14;CL:0000625!9.13e-07!11
|ontology_enrichment_celltype=CL:0000738!3.85e-66!136;CL:0000037!6.94e-55!168;CL:0000566!6.94e-55!168;CL:0002031!4.20e-54!120;CL:0002087!6.62e-54!115;CL:0000988!2.77e-52!177;CL:0002032!4.48e-50!161;CL:0000837!4.48e-50!161;CL:0000860!3.47e-40!42;CL:0002057!3.47e-40!42;CL:0000766!1.76e-33!72;CL:0000473!5.23e-33!48;CL:0000234!5.23e-33!48;CL:0000557!4.79e-30!67;CL:0002009!1.51e-27!61;CL:0000839!3.94e-26!66;CL:0002194!8.39e-26!59;CL:0000576!8.39e-26!59;CL:0000040!8.39e-26!59;CL:0000559!8.39e-26!59;CL:0000763!6.50e-25!108;CL:0000049!6.50e-25!108;CL:0000838!1.40e-24!52;CL:0000542!7.87e-24!53;CL:0000051!7.87e-24!53;CL:0002242!2.03e-22!55;CL:0000134!2.30e-20!354;CL:0002320!1.13e-19!361;CL:0000219!7.26e-17!386;CL:0000325!1.74e-14!87;CL:0000084!3.12e-14!25;CL:0000827!3.12e-14!25;CL:0000791!1.75e-13!18;CL:0000789!1.75e-13!18;CL:0002420!1.75e-13!18;CL:0002419!1.75e-13!18;CL:0000790!1.75e-13!18;CL:0000034!2.33e-12!441;CL:0000048!5.11e-12!427;CL:0000723!1.07e-11!433;CL:0002393!1.27e-10!9;CL:0002397!1.27e-10!9;CL:0000236!7.68e-09!14;CL:0000945!7.71e-09!24;CL:0000826!7.71e-09!24;CL:0000625!2.46e-08!11;CL:0000624!3.81e-08!6;CL:0000094!1.57e-07!8
|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0002390!1.44e-20!102;UBERON:0003061!1.44e-20!102;UBERON:0002193!1.15e-17!112;UBERON:0002371!2.94e-14!80;UBERON:0001474!4.73e-14!86;UBERON:0007023!3.73e-10!115;UBERON:0002405!6.52e-10!115;UBERON:0004765!6.35e-09!101;UBERON:0001434!6.35e-09!101
|ontology_enrichment_uberon=UBERON:0002390!2.32e-32!98;UBERON:0003061!2.32e-32!98;UBERON:0002371!5.34e-28!76;UBERON:0002193!3.60e-27!108;UBERON:0001474!1.03e-25!82;UBERON:0002405!2.89e-23!93;UBERON:0004765!1.44e-22!90;UBERON:0001434!1.99e-18!100;UBERON:0002384!4.58e-18!371;UBERON:0003081!2.25e-08!203
|pathway_enrichment=6.17544927282532e-06;0.00390905938969842;3;162;TNF alpha/NF-kB down reg. targets (Netpath):NetPath_9
|pathway_enrichment=6.17544927282532e-06;0.00390905938969842;3;162;TNF alpha/NF-kB down reg. targets (Netpath):NetPath_9
|tf_chipseq_enrich=BCL11A#53335;7:4.31709099402716:0.00107808455223402:0.00761182210321585!BCL3#602;6:4.50614384396587:0.00203598686755354:0.011824960096787!BRCA1#672;14:6.14302671750288:2.82527442542498e-08:1.92603678666423e-06!CCNT2#905;28:3.85681835119465:5.0761257913336e-12:6.61854558702984e-10!CEBPB#1051;16:2.77257308724341:8.85618406965618e-05:0.00129760242431372!CHD2#1106;18:4.04766110900225:1.04787550155742e-07:6.1241784838923e-06!E2F1#1869;28:2.9871064786222:2.49079647788142e-09:2.11149588760923e-07!E2F4#1874;14:3.85549661769527:7.64706218551962e-06:0.000217972578491671!E2F6#1876;29:3.16298948302661:2.2426729101714e-10:2.30307292099696e-08!EBF1#1879;14:2.71066382286883:0.000362959321375386:0.0036243530514508!EGR1#1958;33:3.5784763071464:5.64412029062498e-14:9.12486500050436e-12!ELF1#1997;29:2.68445306098736:1.25513880516566e-08:9.32328888141514e-07!ELK4#2005;8:2.82359681016835:0.0065676080623261:0.0280698321501586!EP300#2033;22:3.23971126036762:1.08793059315116e-07:6.34053477779654e-06!ESR1#2099;10:6.68882680351184:1.82003034097748e-06:6.75487380175364e-05!FOS#2353;13:2.5429004133832:0.00114812904151676:0.00785313045824668!FOSL2#2355;12:4.41657407075522:1.05147803526648e-05:0.000273172424192028!FOXA1#3169;12:2.8908051520136:0.000607265396656524:0.00506890910816901!GABPB1#2553;16:2.4583248125851:0.000365642238697712:0.00364939886920397!GATA1#2623;11:3.24268238221315:0.000413014145073238:0.00393386085702726!GATA3#2625;7:4.14468727174874:0.00136354510042279:0.00897506061278478!GTF2B#2959;5:3.47215542764394:0.0141834843127147:0.0497584453522206!GTF2F1#2962;15:4.15423724242097:1.27657572022556e-06:5.10625398868776e-05!HDAC2#3066;9:2.62479526368775:0.00622874315131898:0.0274888529888275!HEY1#23462;33:2.89834053092366:2.79057128948827e-11:3.26365593396266e-09!HMGN3#9324;22:3.91147934595028:3.33656122442016e-09:2.75468077246812e-07!HSF1#3297;3:10.7146086956522:0.00280936760046875:0.0153801720828933!IRF1#3659;20:3.32050597981039:3.90366729260953e-07:1.8980219197991e-05!JUN#3725;14:3.80825236288497:8.80966587461091e-06:0.000237744882242504!JUND#3727;22:3.34527405915571:6.07520271249101e-08:3.7677440385383e-06!MAX#4149;19:2.66518597111164:2.38683755310401e-05:0.000520415296886493!MEF2A#4205;10:4.07461541514001:0.000128748098105541:0.00171116347900797!MEF2C#4208;5:4.49036461876348:0.00498555779780012:0.0232740332042038!MXI1#4601;25:5.4138976243257:8.99596347527704e-14:1.41495395993141e-11!MYC#4609;26:2.95172453612705:2.08087698330037e-08:1.48041356443397e-06!NFKB1#4790;29:3.45986607177437:2.34035757418545e-11:2.787053645272e-09!NFYA#4800;9:3.60500491953206:0.00071804020229504:0.00573679625822304!NFYB#4801;11:4.0077766475848:6.43485465705113e-05:0.00104696959889042!NR3C1#2908;11:3.58050557919355:0.000175334496021333:0.00213249789565297!NRF1#4899;14:3.71617200582506:1.1653236447232e-05:0.000296552719618046!PAX5#5079;27:3.91474498569133:1.19828201832722e-11:1.48984971085805e-09!PBX3#5090;9:4.28762204740646:0.000202422191565356:0.00240427286078633!POLR2A#5430;44:2.0540856471425:7.59234119205233e-13:1.08919851889664e-10!POU2F2#5452;26:5.14693968481099:6.7909221724601e-14:1.08446042931125e-11!PRDM1#639;3:8.59767102896483:0.00518603874945122:0.0240369547310139!RDBP#7936;3:10.0198959123929:0.00338972538075314:0.0173004705585925!REST#5978;14:2.93696526143027:0.000156449057672803:0.00197287891020163!RFX5#5993;23:6.02395541359755:1.67009377927883e-13:2.55004275166816e-11!RXRA#6256;10:4.36404720415941:7.30215440325001e-05:0.0011468115845429!SIN3A#25942;31:3.64511796807107:4.95966755376827e-13:7.23439552581012e-11!SMARCB1#6598;8:3.17438535324477:0.00325417926254884:0.0168566227557454!SMARCC1#6599;5:4.74601731735125:0.00395057351957136:0.0189654768012187!SP1#6667;30:3.71633568139624:1.06920996712667e-12:1.50090349135406e-10!SP2#6668;6:3.41133006441452:0.00786754628487583:0.0323024989757498!SREBF1#6720;9:9.19679662966075:4.7861079389151e-07:2.25770698749934e-05!SRF#6722;12:3.59926389447856:7.89027074196385e-05:0.00120899645836262!TAF1#6872;42:3.05234660872396:3.92905562788341e-18:8.7307795897982e-16!TAF7#6879;19:4.7223547542077:3.1362546328173e-09:2.61828375377143e-07!TBP#6908;38:3.06211491542745:5.39932691943666e-15:9.47731603595034e-13!TCF12#6938;15:3.46776029419122:1.18181286891873e-05:0.000299000373587701!TCF7L2#6934;17:3.98028264289858:3.48856912736139e-07:1.72429091856364e-05!TFAP2C#7022;11:2.58481553714049:0.00265240747974016:0.0146398258522663!USF1#7391;17:2.35098886331598:0.000377508361736849:0.00374457173439403!YY1#7528;29:3.0961728640383:3.81833363335084e-10:3.78351941492911e-08!ZBTB33#10009;6:4.13018152564972:0.00313755291829468:0.0164739273658327!ZBTB7A#51341;15:2.3973617308291:0.00078613355652227:0.00615880297874348
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9304,0.353482,0.587959,0.140028,0.416672,0.455538,0.0871629,0.545363,0.967978,0.536371,0.565113,0.0577484,0.402912,0.0711668,0.0909881,0.460694,0.610541,0.592482,0.324222,0.00955474,0.533345,0.047452,0.359154,0.113777,0.220079,0.455315,0.0540887,0.580153,0.0940347,0.655476,0.723299,0.404588,0.365073,0.501818,0.0261599,0.0174066,0.342446,0.554763,0.730142,0.597429,0.180384,0.231896,0.90355,0.53213,0.902091,0.760349,0.0138037,0.890407,0.524331,0.0199525,0.0428605,0.373611,0.350295,0.262153,0.0631294,0.0683428,0.000822003,0.0126335,0.557888,0.799172,0.544831,0.624171,0.699978,0.444765,0.688375,0.411821,0.693285,0.731481,0.194568,0.466833,0.517507,0.599986,0.133345,1.21957e-12,0.577917,0.0419751,0.597147,0.00721487,0.000988766,0.618236,0.566798,0.0528543,0.3136,0.0446388,0.771551,0.426246,0.15351,0.793481,3.59076e-06,1.89882e-05,0.28322,0.0885009,0.257948,0.656681,0.526757,0.540181,0.457113,0.470213,0.70032,0.511547,0.833134,0.672839,0.35779,0.723738,0.445179,0.0240439,0.506413,0.0548491,0.844346,0.0651374,0.554482,0.506771,0.737838,0.594498,0.389407,0.341606,0.0807637,0.0443867,0.844404,0.0886434,0.227792,0.405532,0.556863,0.456561,0.919604,0.62933,0.836007,0.705709,0.0479142,0.732097,0.317027,0.771943,0.614274,0.908329,0.918188,0.465649,0.477287,0.162188,0.640648,0.0280349,0.365436,0.287046,0.595625,0.307958,0.388489,0.280287,0.280417,0.546789,0.390249,0.564496,0.0691999,0.948229,0.639104,0.0863578,0.0804351,0.480612,0.499932,0.0393555,0.327634,0.155215,0.427756,0.789075,0.152499,0.220376,0.143281,0.208033,0.482905,0.0666341,0.0924081,0.607018,0.00529905,0.355641,0.180762,0.0222386,0.00380864,0.0014657,0.430806,0.301814,0.1718,0.149333,0.0724117,0.449744,0.971821,0.562644,0.901629,0.767188,0.104959,0.661683,0.922609,0.349339,0.89217,0.655098,0.512504,0.967513,0.545258,0.318415,0.00528288,0.324562,0.369726,0.0661218,0.488272,0.0586512,0.273266,0.122633,0.46211,7.68077e-05,4.88096e-05,0.754482,0.238423,0.111304,0.336831,0.886336,0.0271673,0.0459669,0.113458,0.599137,0.518596,0.96036,0.594851,0.0456492,0.413599,0.439368,0.631201,0.0933293,0.888561,0.799671,0.00741297,0.235581,0.0167043,0.0567361,0.507017,0.0183596,0.0119587,0.112554,0.00155308,0.575542,0.0102999,0.86661,0.00357243,0.038779,0.00587903,0.460606,0.261591,0.970662,0.467659,0.476574,0.237846,0.893959,0.462358,0.73309,0.413519,0.566528,0.45878,0.685648,0.359457,0.516958,0.909816,0.584175,0.752435,0.141864,0.51976,0.196531,0.00233187,0.0322571,0.30656,0.986764,0.92708,0.387831,0.153305,0.952217,0.0384334,0.86873,0.796622,0.000590921,0.633473,0.341853,0.831719,0.988735,0.481472,0.0408739,0.0508044,0.277226,0.574839,0.401971,0.0168839,0.308058,0.656387,0.736853,0.527257,0.308475,0.342331,0.285064,0.575497,0.352439,0.290947,0.546573,0.39347,0.490154,0.260505,0.780027,0.000993257,0.222932,0.193144,0.553838,0.896822,0.726206,0.000739045,0.0281752,0.923946,0.28655,0.81106,0.321913,0.258297,0.137113,0.297983,0.818493,0.462307,0.594296,0.393703,0.334933,0.0164011,0.653201,0.632436,0.25391,0.0312402,0.976218,0.83045,0.403506,0.144627,0.122765,0.95222,0.540828,0.555974,0.869576,0.752371,0.412774,0.810403,0.878512,0.656294,0.036502,0.979832,0.284591,0.369578,0.637244,0.475581,0.683868,0.347294,0.711648,0.730813,0.468413,0.0164245,0.402957,0.485493,0.828566,0.317205,0.849547,0.755011,0.835304,0.0591176,0.977596,0.97201,0.764802,0.454401,0.766462,0.936655,0.444325,0.472506,0.971746,0.889582,0.583923,0.841326,0.894937,0.898288,0.76613,0.50579,0.32646,0.659293,0.613942,0.867098,0.854439,0.398349,0.191655,0.00120686,0.585899,0.10506,0.561228,0.159653,0.365217,0.0300644,0.81028,0.53786,0.656594,0.481539,0.6986,0.28017,0.224336,0.761342,0.509464,0.759956,0.941219,0.452239,0.649563,0.00994998,0.000100851,0.523587,0.670236,0.222391,0.728993,0.859637,0.472787,0.828021,0.61,0.886508,0.129115,0.733679,0.426315,0.332443,0.838351,0.118235,0.193934,0.930838,0.0185487,0.243534,0.516866,0.601658,0.380495,0.608074,0.319668,0.484102,0.682877,0.462109,0.168306,0.971762,0.416107,0.962691,0.813995,0.56343,0.199412,0.806589,0.557053,0.967607,0.900618,0.434255,0.79209,0.123857,0.884026,0.666756,0.741418,0.553233,0.949359,0.790575,0.137476,0.345417,0.569479,0.726818,0.378783,0.454966,0.822851,0.207394,0.571527,0.918922,0.712199,0.471385,0.571262,4.7309e-05,0.00313135,0.493312,0.61762,0.0238409,0.402533,0.727471,0.794732,0.0833648,0.141701,0.26866,0.504935,0.650864,0.703641,0.0634325,0.830106,0.499288,0.654437,0.762956,0.11343,0.651051,0.143176,0.0219059,0.965226,0.636109,0.209549,0.502159,0.989256,0.855808,0.558223,0.00150898,0.294174,0.184617,0.750745,0.848568,0.00180008,0.502802,0.868442,0.853947,0.591262,0.592801,0.559131,0.848534,0.520668,0.979457,0.55999,0.645701,0.961221,0.745191,0.253436,0.45077,0.761729,0.745897,0.778315,0.941774,0.551392,0.478736,0.202638,0.747824,0.980154,0.944323,0.74257,0.058882,0.312333,0.711531,0.804645,0.740642,0.79588,0.00562037,0.173576,0.164921,0.867877,0.531878
}}
}}

Revision as of 14:26, 19 October 2012


Full id: C280_Mast_Natural_CD19_CD8_Eosinophils_CD34_CD4



Phase1 CAGE Peaks

Hg19::chr10:3827417..3827428,-p3@KLF6
Hg19::chr11:62323018..62323031,-p@chr11:62323018..62323031
-
Hg19::chr11:65657918..65657945,-p@chr11:65657918..65657945
-
Hg19::chr11:66610757..66610775,-p3@CU688443
Hg19::chr12:25539082..25539099,-p@chr12:25539082..25539099
-
Hg19::chr12:9913489..9913506,-p1@CD69
Hg19::chr14:105947382..105947418,+p@chr14:105947382..105947418
+
Hg19::chr14:105947980..105947997,-p@chr14:105947980..105947997
-
Hg19::chr14:60715694..60715716,-p1@ENST00000529171
Hg19::chr14:75725656..75725708,-p@chr14:75725656..75725708
-
Hg19::chr14:75761343..75761358,+p@chr14:75761343..75761358
+
Hg19::chr17:17586443..17586462,-p@chr17:17586443..17586462
-
Hg19::chr17:17739693..17739737,+p@chr17:17739693..17739737
+
Hg19::chr17:38478879..38478895,-p@chr17:38478879..38478895
-
Hg19::chr17:62972061..62972090,-p7@AMZ2P1
Hg19::chr19:14117737..14117757,+p@chr19:14117737..14117757
+
Hg19::chr19:39892410..39892428,+p@chr19:39892410..39892428
+
Hg19::chr19:39892441..39892455,+p@chr19:39892441..39892455
+
Hg19::chr19:45954222..45954237,+p@chr19:45954222..45954237
+
Hg19::chr19:45954249..45954276,+p@chr19:45954249..45954276
+
Hg19::chr19:45954279..45954294,+p@chr19:45954279..45954294
+
Hg19::chr19:45972701..45972774,+p2@FOSB
Hg19::chr19:50554282..50554297,-p@chr19:50554282..50554297
-
Hg19::chr19:58609835..58609860,+p@chr19:58609835..58609860
+
Hg19::chr1:150207241..150207263,+p@chr1:150207241..150207263
+
Hg19::chr1:150584212..150584225,+p@chr1:150584212..150584225
+
Hg19::chr1:156076042..156076062,-p@chr1:156076042..156076062
-
Hg19::chr1:171455188..171455201,-p3@BC007549
Hg19::chr1:19923143..19923206,-p1@ENST00000416470
Hg19::chr1:245132972..245133020,+p2@EFCAB2
Hg19::chr1:245133062..245133098,+p3@EFCAB2
Hg19::chr20:34384518..34384529,-p@chr20:34384518..34384529
-
Hg19::chr21:44847380..44847401,+p@chr21:44847380..44847401
+
Hg19::chr22:42078575..42078594,+p@chr22:42078575..42078594
+
Hg19::chr2:157189859..157189868,+p@chr2:157189859..157189868
+
Hg19::chr2:201729344..201729359,-p3@CLK1
Hg19::chr2:24149009..24149030,+p@chr2:24149009..24149030
+
Hg19::chr2:25195035..25195063,+p2@DNAJC27-AS1
Hg19::chr3:20227985..20227998,+p@chr3:20227985..20227998
+
Hg19::chr6:116575441..116575452,+p4@uc003pwo.1
Hg19::chr6:157342586..157342600,-p@chr6:157342586..157342600
-
Hg19::chr6:16129308..16129327,+p1@MYLIP
Hg19::chr8:101964446..101964498,+p@chr8:101964446..101964498
+
Hg19::chr9:3525727..3525828,-p2@RFX3
Hg19::chr9:3526503..3526519,+p2@ENST00000423112
Hg19::chr9:91933575..91933588,-p@chr9:91933575..91933588
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

p.valueFDRnGenesnPathwayName
6.17544927282532e-060.003909059389698423162TNF alpha/NF-kB down reg. targets (Netpath):NetPath_9



Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
leukocyte3.85e-66136
hematopoietic stem cell6.94e-55168
angioblastic mesenchymal cell6.94e-55168
hematopoietic lineage restricted progenitor cell4.20e-54120
nongranular leukocyte6.62e-54115
hematopoietic cell2.77e-52177
hematopoietic oligopotent progenitor cell4.48e-50161
hematopoietic multipotent progenitor cell4.48e-50161
classical monocyte3.47e-4042
CD14-positive, CD16-negative classical monocyte3.47e-4042
myeloid leukocyte1.76e-3372
defensive cell5.23e-3348
phagocyte5.23e-3348
granulocyte monocyte progenitor cell4.79e-3067
macrophage dendritic cell progenitor1.51e-2761
myeloid lineage restricted progenitor cell3.94e-2666
monopoietic cell8.39e-2659
monocyte8.39e-2659
monoblast8.39e-2659
promonocyte8.39e-2659
myeloid cell6.50e-25108
common myeloid progenitor6.50e-25108
lymphoid lineage restricted progenitor cell1.40e-2452
lymphocyte7.87e-2453
common lymphoid progenitor7.87e-2453
nucleate cell2.03e-2255
mesenchymal cell2.30e-20354
connective tissue cell1.13e-19361
motile cell7.26e-17386
stuff accumulating cell1.74e-1487
T cell3.12e-1425
pro-T cell3.12e-1425
mature alpha-beta T cell1.75e-1318
alpha-beta T cell1.75e-1318
immature T cell1.75e-1318
mature T cell1.75e-1318
immature alpha-beta T cell1.75e-1318
stem cell2.33e-12441
multi fate stem cell5.11e-12427
somatic stem cell1.07e-11433
intermediate monocyte1.27e-109
CD14-positive, CD16-positive monocyte1.27e-109
B cell7.68e-0914
lymphocyte of B lineage7.71e-0924
pro-B cell7.71e-0924
CD8-positive, alpha-beta T cell2.46e-0811
CD4-positive, alpha-beta T cell3.81e-086
granulocyte1.57e-078
Uber Anatomy
Ontology termp-valuen
hematopoietic system2.32e-3298
blood island2.32e-3298
bone marrow5.34e-2876
hemolymphoid system3.60e-27108
bone element1.03e-2582
immune system2.89e-2393
skeletal element1.44e-2290
skeletal system1.99e-18100
connective tissue4.58e-18371
lateral plate mesoderm2.25e-08203


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
BCL11A#5333574.317090994027160.001078084552234020.00761182210321585
BCL3#60264.506143843965870.002035986867553540.011824960096787
BRCA1#672146.143026717502882.82527442542498e-081.92603678666423e-06
CCNT2#905283.856818351194655.0761257913336e-126.61854558702984e-10
CEBPB#1051162.772573087243418.85618406965618e-050.00129760242431372
CHD2#1106184.047661109002251.04787550155742e-076.1241784838923e-06
E2F1#1869282.98710647862222.49079647788142e-092.11149588760923e-07
E2F4#1874143.855496617695277.64706218551962e-060.000217972578491671
E2F6#1876293.162989483026612.2426729101714e-102.30307292099696e-08
EBF1#1879142.710663822868830.0003629593213753860.0036243530514508
EGR1#1958333.57847630714645.64412029062498e-149.12486500050436e-12
ELF1#1997292.684453060987361.25513880516566e-089.32328888141514e-07
ELK4#200582.823596810168350.00656760806232610.0280698321501586
EP300#2033223.239711260367621.08793059315116e-076.34053477779654e-06
ESR1#2099106.688826803511841.82003034097748e-066.75487380175364e-05
FOS#2353132.54290041338320.001148129041516760.00785313045824668
FOSL2#2355124.416574070755221.05147803526648e-050.000273172424192028
FOXA1#3169122.89080515201360.0006072653966565240.00506890910816901
GABPB1#2553162.45832481258510.0003656422386977120.00364939886920397
GATA1#2623113.242682382213150.0004130141450732380.00393386085702726
GATA3#262574.144687271748740.001363545100422790.00897506061278478
GTF2B#295953.472155427643940.01418348431271470.0497584453522206
GTF2F1#2962154.154237242420971.27657572022556e-065.10625398868776e-05
HDAC2#306692.624795263687750.006228743151318980.0274888529888275
HEY1#23462332.898340530923662.79057128948827e-113.26365593396266e-09
HMGN3#9324223.911479345950283.33656122442016e-092.75468077246812e-07
HSF1#3297310.71460869565220.002809367600468750.0153801720828933
IRF1#3659203.320505979810393.90366729260953e-071.8980219197991e-05
JUN#3725143.808252362884978.80966587461091e-060.000237744882242504
JUND#3727223.345274059155716.07520271249101e-083.7677440385383e-06
MAX#4149192.665185971111642.38683755310401e-050.000520415296886493
MEF2A#4205104.074615415140010.0001287480981055410.00171116347900797
MEF2C#420854.490364618763480.004985557797800120.0232740332042038
MXI1#4601255.41389762432578.99596347527704e-141.41495395993141e-11
MYC#4609262.951724536127052.08087698330037e-081.48041356443397e-06
NFKB1#4790293.459866071774372.34035757418545e-112.787053645272e-09
NFYA#480093.605004919532060.000718040202295040.00573679625822304
NFYB#4801114.00777664758486.43485465705113e-050.00104696959889042
NR3C1#2908113.580505579193550.0001753344960213330.00213249789565297
NRF1#4899143.716172005825061.1653236447232e-050.000296552719618046
PAX5#5079273.914744985691331.19828201832722e-111.48984971085805e-09
PBX3#509094.287622047406460.0002024221915653560.00240427286078633
POLR2A#5430442.05408564714257.59234119205233e-131.08919851889664e-10
POU2F2#5452265.146939684810996.7909221724601e-141.08446042931125e-11
PRDM1#63938.597671028964830.005186038749451220.0240369547310139
RDBP#7936310.01989591239290.003389725380753140.0173004705585925
REST#5978142.936965261430270.0001564490576728030.00197287891020163
RFX5#5993236.023955413597551.67009377927883e-132.55004275166816e-11
RXRA#6256104.364047204159417.30215440325001e-050.0011468115845429
SIN3A#25942313.645117968071074.95966755376827e-137.23439552581012e-11
SMARCB1#659883.174385353244770.003254179262548840.0168566227557454
SMARCC1#659954.746017317351250.003950573519571360.0189654768012187
SP1#6667303.716335681396241.06920996712667e-121.50090349135406e-10
SP2#666863.411330064414520.007867546284875830.0323024989757498
SREBF1#672099.196796629660754.7861079389151e-072.25770698749934e-05
SRF#6722123.599263894478567.89027074196385e-050.00120899645836262
TAF1#6872423.052346608723963.92905562788341e-188.7307795897982e-16
TAF7#6879194.72235475420773.1362546328173e-092.61828375377143e-07
TBP#6908383.062114915427455.39932691943666e-159.47731603595034e-13
TCF12#6938153.467760294191221.18181286891873e-050.000299000373587701
TCF7L2#6934173.980282642898583.48856912736139e-071.72429091856364e-05
TFAP2C#7022112.584815537140490.002652407479740160.0146398258522663
USF1#7391172.350988863315980.0003775083617368490.00374457173439403
YY1#7528293.09617286403833.81833363335084e-103.78351941492911e-08
ZBTB33#1000964.130181525649720.003137552918294680.0164739273658327
ZBTB7A#51341152.39736173082910.000786133556522270.00615880297874348



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

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