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{{Coexpression_clusters
{{Coexpression_clusters
|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0319790978673642,0,0.0329050193664387,0.144064671875115,0,0.165674064961392,0,0,0,0,0.057730457053664,0,0.507313559908549,1.00106272607812,0.792969959510598,0,0,0,0.482241016522323,0.399933835234624,0.34496577392992,0.67383751528609,0.773348614634313,0.602872524704688,0.748426689770576,0.66145771448084,0.350673490455787,0.765403243489262,0.641988115773021,0.569201765171362,0.698188197105211,0.541453612078576,0.291561130040146,0.697150028882196,0.415748562090744,0.68448833566647,0.298755709453128,0.557606593427159,0.495700232751619,0.99984737936768,0.696504615391315,0.614276030777965,0.895813530161878,1.07740938067351,0.401840684896235,0.665805773168088,0.453530569481038,0.412008702850566,0.180246580925176,0.301531442707928,0.152079493649239,0.327008559924594,0.24325748919447,0.388550595315416,0.0489018692844709,0.145455399178477,0.0796676883963131,0,0,0,0,0,0,0,0,0.195681888795628,0.139821868884298,0.140593896684098,0,0,0,0.083261934772818,0.410278233557711,0.208657508460569,0,0,0,0,0,0,0,0.104078526590485,0.0523442574910016,0.0531012520152427,0.0661163340840885,0,0,0,0,0,0,0,0,0.0686539798597396,0,0,0,0,0,0,0,0,0.256820409353761,0.368696059538965,0.198463979662155,0,0,0,0,0,0,0,0,0,0,0,0.0449580749545185,0,0,0,0,0.0542137952531537,0.02214757755956,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.560577092055277,0.652709074935565,0,0,0,0.0540033816753664,0.109523411542048,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.187004028169722,0,0,0,0,0.0995565284045724,0,0.126310890838218,0,0.0977547706744154,0,0,0.0711224080461804,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0810931932687443,0.057546229904239,0.020225860711375,0,0,0,0,0,0,0.173961836914205,0.101796995028086,0.0382462855462598,0.00904730862265854,0.0516318862226721,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.492528432668985,0,0,0,0,0,0,0,0.208818370510298,0.360549006701814,0.426260611157522,0,0,0,0,0,0.999482198615591,1.20298044633303,0.5423888076298,0,0,0,0.0820564584332857,0.0713034174053426,0,0,0,0,0,0,0,0,0,0,0.261755686906388,0.306871673988367,0.185722801069447,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0425916600387234,0.0380513783661453,0.0227539793633894,0,0,0,0,0,0,0,0,0,0,0,0,0,0.016644813772392,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0390744040629657,0,0,0,0,0,0.124939875660588,0.195802046114694,0.12500461485436,0.0568365595237027,0,0.126709624667596,0,0,0,0,0,0,0.0840131281069015,0,0,0,0.0833856393724342,0,0.107480362063099,0,0,0,0,0.0210990751343502,0.0798320938648321,0,0,0,0,0,0,0,0,0,0,0,0,0.0583945787235586,0,0.00081716947734918,0,0,0,0,0,0.0571597974145305,0.0458347162451775,0,0,0.0789089986057754,0,0,0,0.0504125515893149,0,0,0.0715216048933879,0,0,0,0,0,0.0385280079017836,0,0,0,0,0,0,0,0,0,0,0,0.0494492378997174,0,0.0867720438244607,0,0,0,0,0.0321956448428329,0,0,0.0108836128867963,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0549201943193819,0,0,0,0,0,0,0,0,0.0978631351411755,0,0,0,0,0,0,0,0.0197406134363507,0,0,0,0.0699368280688007,0,0,0,0,0,0,0,0,0,0.0266602233572113,0,0,0,0,0,0,0.0332623591788961,0,0,0,0,0,0,0,0,0.105104912336182,0,0,0,0.0714512758514353,0.0896085685791025,0,0,0,0,0.0547535628453514,0,0,0,0,0,0,0,0,0.0622217579787005,0,0,0,0.0906072166380584,0,0.0256128589246175,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0342643952743103,0,0,0,0,0.0998759650431728,0.101906882599192,0,0,0.0440642112897698,0.0634100406668813,0.150522826464445,0,0,0,0,0,0,0,0,0,0,3.66977256590906e-05,0.0512262229954782,0,0.0870207733122038,0.0508408017580101,0,0,0,0.0383152234213799,0,0,0,0,0,0,0.075329031500352,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.106026559445686,0.0773171348687735,0,0.0281117036291189,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0329657938672155,0,0,0,0.0270351810347199,0,0.120332935578059,0,0,0,0.0650101077405693,0,0,0,0,0,0,0,0,3.67095291906594e-05,0,0,0,0,0,0,0,0.0815945607332269,0.0267031128419265,0,0,0.131413866294317,0,0,0,0.125898678133584,0,0.0890788809625826,0.0369091684033041,0,0,0.0322537268383439,0,0,0,0,0.0321026899668968,0,0,0,0.114032057865062,0.0580284054719272,0,0,0,0,0,0.0248734439502885,0,0,0,0,0,0,0,0,0.0131050867168601,0,0,0,0,0,0,0,0,0,0,0.0452997049655463,0,0,0,0,0.0622778521897,0,0.0778431765528363,0.112955512742184,0,0,0.0390109377342095,0.0197183067243338,0.0413694521212564,0.0105295018951914,0,0,0,0,0.109470268990959,0,0.0179064127138926,0,0,0,0,0,0,0,0,0,0,0,0,0.0283423537660401,0.103106967823645,0,0.106788054538657,0.0283751599101605,0,0,0.0508240440617333,0,0,0.079946807131842,0,0,0.0283076897745917,0,0,0,0,0,0,0,0.0500863030838633,0,0,0,0
|full_id=C273_Neutrophils_CD14_Eosinophils_Monocytederived_CD4_Natural_Mast
|full_id=C273_Neutrophils_CD14_Eosinophils_Monocytederived_CD4_Natural_Mast
|gostat_on_coexpression_clusters=GO:0004691!cAMP-dependent protein kinase activity!0.0302731887304975!11214$GO:0004708!MAP kinase kinase activity!0.0302731887304975!5606$GO:0004712!protein serine/threonine/tyrosine kinase activity!0.0302731887304975!5606$GO:0004690!cyclic nucleotide-dependent protein kinase activity!0.0302731887304975!11214$GO:0004674!protein serine/threonine kinase activity!0.0302731887304975!11214;5606
|gostat_on_coexpression_clusters=GO:0004691!cAMP-dependent protein kinase activity!0.0302731887304975!11214$GO:0004708!MAP kinase kinase activity!0.0302731887304975!5606$GO:0004712!protein serine/threonine/tyrosine kinase activity!0.0302731887304975!5606$GO:0004690!cyclic nucleotide-dependent protein kinase activity!0.0302731887304975!11214$GO:0004674!protein serine/threonine kinase activity!0.0302731887304975!11214;5606

Revision as of 15:31, 12 September 2012


Full id: C273_Neutrophils_CD14_Eosinophils_Monocytederived_CD4_Natural_Mast



Phase1 CAGE Peaks

Hg19::chr10:121154442..121154449,-p@chr10:121154442..121154449
-
Hg19::chr11:47377641..47377656,-p@chr11:47377641..47377656
-
Hg19::chr11:47377786..47377798,-p@chr11:47377786..47377798
-
Hg19::chr11:47378636..47378650,-p@chr11:47378636..47378650
-
Hg19::chr11:47379735..47379747,-p@chr11:47379735..47379747
-
Hg19::chr11:47379860..47379874,-p@chr11:47379860..47379874
-
Hg19::chr14:35871286..35871297,-p@chr14:35871286..35871297
-
Hg19::chr15:58447767..58447778,+p@chr15:58447767..58447778
+
Hg19::chr15:86212972..86212989,+p20@AKAP13
Hg19::chr16:31926161..31926175,+p@chr16:31926161..31926175
+
Hg19::chr17:21194520..21194548,+p7@MAP2K3
Hg19::chr19:47993823..47993862,-p@chr19:47993823..47993862
-
Hg19::chr1:183556727..183556731,-p@chr1:183556727..183556731
-
Hg19::chr1:27947499..27947502,-p@chr1:27947499..27947502
-
Hg19::chr1:27951156..27951162,-p@chr1:27951156..27951162
-
Hg19::chr1:27951294..27951312,-p@chr1:27951294..27951312
-
Hg19::chr1:27951368..27951397,-p@chr1:27951368..27951397
-
Hg19::chr1:27951398..27951454,-p@chr1:27951398..27951454
-
Hg19::chr1:27955714..27955719,-p@chr1:27955714..27955719
-
Hg19::chr1:33424609..33424645,-p@chr1:33424609..33424645
-
Hg19::chr1:89589346..89589358,-p@chr1:89589346..89589358
-
Hg19::chr20:48500628..48500646,+p@chr20:48500628..48500646
+
Hg19::chr22:35738610..35738623,+p@chr22:35738610..35738623
+
Hg19::chr22:35738627..35738686,+p@chr22:35738627..35738686
+
Hg19::chr22:35738688..35738740,+p@chr22:35738688..35738740
+
Hg19::chr22:35738813..35738828,+p@chr22:35738813..35738828
+
Hg19::chr22:35738894..35738925,+p@chr22:35738894..35738925
+
Hg19::chr22:35738945..35738954,+p@chr22:35738945..35738954
+
Hg19::chr22:35738968..35738980,+p@chr22:35738968..35738980
+
Hg19::chr22:35739061..35739082,+p@chr22:35739061..35739082
+
Hg19::chr22:35739086..35739098,+p@chr22:35739086..35739098
+
Hg19::chr22:35739277..35739390,+p@chr22:35739277..35739390
+
Hg19::chr22:35739411..35739459,+p@chr22:35739411..35739459
+
Hg19::chr22:35739472..35739491,+p@chr22:35739472..35739491
+
Hg19::chr22:35739601..35739650,+p@chr22:35739601..35739650
+
Hg19::chr22:35739658..35739678,+p@chr22:35739658..35739678
+
Hg19::chr22:35739706..35739737,+p4@TOM1
Hg19::chr22:35739742..35739814,+p2@TOM1
Hg19::chr22:35739816..35739887,+p3@TOM1
Hg19::chr2:114700995..114701006,+p@chr2:114700995..114701006
+
Hg19::chr2:145240683..145240706,-p@chr2:145240683..145240706
-
Hg19::chr2:145246478..145246502,-p@chr2:145246478..145246502
-
Hg19::chr2:28619598..28619640,+p@chr2:28619598..28619640
+
Hg19::chr5:169716803..169716815,-p@chr5:169716803..169716815
-
Hg19::chr6:13316777..13316781,-p@chr6:13316777..13316781
-
Hg19::chr7:130586359..130586363,-p@chr7:130586359..130586363
-
Hg19::chr8:59473361..59473383,+p@chr8:59473361..59473383
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0004691cAMP-dependent protein kinase activity0.0302731887304975
GO:0004708MAP kinase kinase activity0.0302731887304975
GO:0004712protein serine/threonine/tyrosine kinase activity0.0302731887304975
GO:0004690cyclic nucleotide-dependent protein kinase activity0.0302731887304975
GO:0004674protein serine/threonine kinase activity0.0302731887304975



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
hematopoietic system3.23e-25102
blood island3.23e-25102
hemolymphoid system1.44e-22112
bone marrow7.37e-2180
bone element1.60e-2086
adult organism2.79e-20115
skeletal element2.34e-15101
skeletal system2.34e-15101
immune system4.04e-14115
neural tube6.08e-1157
neural rod6.08e-1157
future spinal cord6.08e-1157
neural keel6.08e-1157
regional part of forebrain4.35e-0941
forebrain4.35e-0941
future forebrain4.35e-0941
anterior neural tube4.64e-0942
regional part of brain3.68e-0859
brain1.92e-0769
future brain1.92e-0769
gray matter2.35e-0734
brain grey matter2.35e-0734
telencephalon5.20e-0734
regional part of telencephalon6.25e-0733


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

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