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{{CL
{{CL
|id=CL:0002431
|alt_id=
|name=CD4-positive, CD8-intermediate double-positive thymocyte
|namespace=cell;;efo
|def="A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive,  and is in the process of down regulating the CD4 co-receptor." [GOC:tfm, http://www.immgen.org/index_content.html]
|xref=
|is_a=CL:0000809
|synonym="T.4int8+.th" EXACT []
|comment=
|comment=
|alt_id=
|disjoint_from=
|union_of=
|created_by=tmeehan
|created_by=tmeehan
|obo_creation_date=2010-10-21T02:29:23Z
|def="A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive,  and is in the process of down regulating the CD4 co-receptor." [GOC:tfm, http://www.immgen.org/index_content.html]
|subset=
|derives_from=
|derives_from=
|develops_from=CL:0002429
|develops_from=CL:0002429
|disjoint_from=
|has_quality=
|has_quality=
|id=CL:0002431
|is_a=CL:0000809
|is_obsolete=
|located_in=
|located_in=
|name=CD4-positive, CD8-intermediate double-positive thymocyte
|namespace=cell;;efo
|obo_creation_date=2010-10-21T02:29:23Z
|part_of=
|part_of=
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl
|is_obsolete=
|subset=
|preceded_by=
|synonym="T.4int8+.th" EXACT []
|union_of=
|xref=
}}
}}

Revision as of 10:27, 12 September 2014

Name:CD4-positive, CD8-intermediate double-positive thymocyte
Namespace:cell;;efo
Definition:"A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD4 co-receptor." [GOC:tfm, http://www.immgen.org/index_content.html]
Synonyms: "T.4int8+.th" EXACT []
Created by:tmeehan
Creation date:2010-10-21T02:29:23Z


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:CL:0000809(double-positive, alpha-beta thymocyte)
develops_from:CL:0002429(CD69-positive double-positive thymocyte)



Children


develops from:CL:0002433 (CD69-positive, CD4-positive single-positive thymocyte)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.



Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0002431 (CD4-positive, CD8-intermediate double-positive thymocyte), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
2.55e-98FFCP PHASE1:Hg19::chr1:183622379..183622388,-#_a9a14d073e6c889dd2ac2106f15d43b9p4@APOBEC4
2.55e-98FFCP PHASE2:Hg19::chr1:183622379..183622388,-#_a9a14d073e6c889dd2ac2106f15d43b9p4@APOBEC4
2.55e-98FFCP PHASE1:Hg19::chr2:162762361..162762364,+#_a9a14d073e6c889dd2ac2106f15d43b9p@chr2:162762361..162762364, +
2.55e-98FFCP PHASE2:Hg19::chr2:162762361..162762364,+#_a9a14d073e6c889dd2ac2106f15d43b9p@chr2:162762361..162762364, +
1.36e-86FFCP PHASE2:Mm9::chr13:30878406..30878419,+#_4d75394299cde7064e7339cb4d0adc52p@chr13:30878406..30878419, +
1.36e-86FFCP PHASE2:Mm9::chrX:54476786..54476810,+#_4d75394299cde7064e7339cb4d0adc52p@chrX:54476786..54476810, +
1.36e-86FFCP PHASE1:Mm9::chrX:54476786..54476810,+#_4d75394299cde7064e7339cb4d0adc52p@chrX:54476786..54476810, +
1.36e-86FFCP PHASE1:Mm9::chr13:30878406..30878419,+#_4d75394299cde7064e7339cb4d0adc52p@chr13:30878406..30878419, +
1.01e-74FFCP PHASE2:Mm9::chr16:52032670..52032685,+#_7f0b4793417bab67ff55692e3855b8a4p@chr16:52032670..52032685, +
1.01e-74FFCP PHASE1:Mm9::chr16:52032670..52032685,+#_7f0b4793417bab67ff55692e3855b8a4p@chr16:52032670..52032685, +
2.41e-74FFCP PHASE2:Mm9::chr16:93777453..93777464,+#_03c3d92a6e6ac583f7859c11845d00fdp@chr16:93777453..93777464, +
2.41e-74FFCP PHASE2:Mm9::chr14:54795946..54795960,+#_03c3d92a6e6ac583f7859c11845d00fdp1@ENSMUST00000103701
2.41e-74FFCP PHASE1:Mm9::chr16:93777453..93777464,+#_03c3d92a6e6ac583f7859c11845d00fdp@chr16:93777453..93777464, +
2.41e-74FFCP PHASE1:Mm9::chr14:54795946..54795960,+#_03c3d92a6e6ac583f7859c11845d00fdp1@ENSMUST00000103701
2.48e-72FFCP PHASE1:Mm9::chr13:30853488..30853499,+#_21c7f1a8ae1b768a1fc0215bf834b782p@chr13:30853488..30853499, +
2.48e-72FFCP PHASE1:Mm9::chr15:80403112..80403122,+#_21c7f1a8ae1b768a1fc0215bf834b782p12@Grap2
2.48e-72FFCP PHASE2:Mm9::chr15:80403112..80403122,+#_21c7f1a8ae1b768a1fc0215bf834b782p12@Grap2
2.48e-72FFCP PHASE2:Mm9::chr14:122362270..122362291,-#_21c7f1a8ae1b768a1fc0215bf834b782p@chr14:122362270..122362291, -
2.48e-72FFCP PHASE2:Mm9::chr14:54827490..54827502,+#_21c7f1a8ae1b768a1fc0215bf834b782p@chr14:54827490..54827502, +
2.48e-72FFCP PHASE1:Mm9::chr14:122362270..122362291,-#_21c7f1a8ae1b768a1fc0215bf834b782p@chr14:122362270..122362291, -
2.48e-72FFCP PHASE1:Mm9::chr11:11587720..11587735,+#_21c7f1a8ae1b768a1fc0215bf834b782p@chr11:11587720..11587735, +
2.48e-72FFCP PHASE2:Mm9::chr11:11587720..11587735,+#_21c7f1a8ae1b768a1fc0215bf834b782p@chr11:11587720..11587735, +
2.48e-72FFCP PHASE1:Mm9::chr11:11592840..11592849,+#_21c7f1a8ae1b768a1fc0215bf834b782p@chr11:11592840..11592849, +
2.48e-72FFCP PHASE2:Mm9::chr13:30853488..30853499,+#_21c7f1a8ae1b768a1fc0215bf834b782p@chr13:30853488..30853499, +
2.48e-72FFCP PHASE1:Mm9::chr14:54827490..54827502,+#_21c7f1a8ae1b768a1fc0215bf834b782p@chr14:54827490..54827502, +
2.48e-72FFCP PHASE2:Mm9::chr11:11592840..11592849,+#_21c7f1a8ae1b768a1fc0215bf834b782p@chr11:11592840..11592849, +
2.39e-66FFCP PHASE1:Hg19::chr9:75772924..75772957,+#_552fe0a51e21b2ce33571016b5fe62bep17@ANXA1
2.39e-66FFCP PHASE2:Hg19::chr9:75772924..75772957,+#_552fe0a51e21b2ce33571016b5fe62bep17@ANXA1
4.66e-66FFCP PHASE1:Hg19::chr20:37493438..37493456,-#_594a8f0b5f57f605dfeb4c3ed67c8debp@chr20:37493438..37493456, -
4.66e-66FFCP PHASE1:Hg19::chr11:118209514..118209525,+#_594a8f0b5f57f605dfeb4c3ed67c8debp@chr11:118209514..118209525, +
4.66e-66FFCP PHASE2:Hg19::chr20:37493438..37493456,-#_594a8f0b5f57f605dfeb4c3ed67c8debp@chr20:37493438..37493456, -
4.66e-66FFCP PHASE2:Hg19::chr2:204816181..204816219,-#_594a8f0b5f57f605dfeb4c3ed67c8debp@chr2:204816181..204816219, -
4.66e-66FFCP PHASE2:Hg19::chr11:118209514..118209525,+#_594a8f0b5f57f605dfeb4c3ed67c8debp@chr11:118209514..118209525, +
4.66e-66FFCP PHASE1:Hg19::chr2:204816181..204816219,-#_594a8f0b5f57f605dfeb4c3ed67c8debp@chr2:204816181..204816219, -
1.05e-65FFCP PHASE2:Mm9::chr14:53242248..53242261,+#_846b13d8502994ac6c1b75424760f2aap@chr14:53242248..53242261, +
1.05e-65FFCP PHASE1:Mm9::chr14:53242248..53242261,+#_846b13d8502994ac6c1b75424760f2aap@chr14:53242248..53242261, +
1.74e-65FFCP PHASE2:Mm9::chr5:123439274..123439290,+#_31fcf082dc24a8fa08be21aab73078ecp4@ENSMUST00000148466, p4@uc008zmw.1
1.74e-65FFCP PHASE1:Mm9::chr5:123439274..123439290,+#_31fcf082dc24a8fa08be21aab73078ecp4@ENSMUST00000148466, p4@uc008zmw.1
2.25e-65FFCP PHASE1:Mm9::chr5:123465978..123465989,-#_0ba8b3ddd803acc13519a79f07088d24p@chr5:123465978..123465989, -
2.25e-65FFCP PHASE2:Mm9::chr5:123465978..123465989,-#_0ba8b3ddd803acc13519a79f07088d24p@chr5:123465978..123465989, -
2.25e-65FFCP PHASE2:Mm9::chr15:80403104..80403111,+#_0ba8b3ddd803acc13519a79f07088d24p10@Grap2
2.25e-65FFCP PHASE1:Mm9::chr1:140069290..140069308,+#_0ba8b3ddd803acc13519a79f07088d24p@chr1:140069290..140069308, +
2.25e-65FFCP PHASE2:Mm9::chr1:140069290..140069308,+#_0ba8b3ddd803acc13519a79f07088d24p@chr1:140069290..140069308, +
2.25e-65FFCP PHASE1:Mm9::chr15:80403104..80403111,+#_0ba8b3ddd803acc13519a79f07088d24p10@Grap2
2.9e-65FFCP PHASE2:Mm9::chr11:46200242..46200255,+#_8fbeb3c66307d49c1e296e4203b2f878p@chr11:46200242..46200255, +
2.9e-65FFCP PHASE1:Mm9::chr14:54817583..54817593,-#_8fbeb3c66307d49c1e296e4203b2f878p@chr14:54817583..54817593, -
2.9e-65FFCP PHASE1:Mm9::chr6:41504409..41504422,-#_8fbeb3c66307d49c1e296e4203b2f878p@chr6:41504409..41504422, -
2.9e-65FFCP PHASE2:Mm9::chr14:54817583..54817593,-#_8fbeb3c66307d49c1e296e4203b2f878p@chr14:54817583..54817593, -
2.9e-65FFCP PHASE2:Mm9::chr6:41504409..41504422,-#_8fbeb3c66307d49c1e296e4203b2f878p@chr6:41504409..41504422, -
2.9e-65FFCP PHASE1:Mm9::chr11:46200242..46200255,+#_8fbeb3c66307d49c1e296e4203b2f878p@chr11:46200242..46200255, +
3.74e-65FFCP PHASE2:Mm9::chr4:32328217..32328228,-#_d6064b3a4c2ddd8786ab88760eef8c5bp@chr4:32328217..32328228, -
3.74e-65FFCP PHASE1:Mm9::chr4:32328217..32328228,-#_d6064b3a4c2ddd8786ab88760eef8c5bp@chr4:32328217..32328228, -
6.21e-65FFCP PHASE2:Mm9::chr5:123465955..123465966,-#_ea38d4afafa4ec5d602175dd55fde27cp@chr5:123465955..123465966, -
6.21e-65FFCP PHASE2:Mm9::chr11:46200110..46200124,-#_ea38d4afafa4ec5d602175dd55fde27cp@chr11:46200110..46200124, -
6.21e-65FFCP PHASE1:Mm9::chr11:46200110..46200124,-#_ea38d4afafa4ec5d602175dd55fde27cp@chr11:46200110..46200124, -
6.21e-65FFCP PHASE1:Mm9::chr13:105412781..105412798,+#_ea38d4afafa4ec5d602175dd55fde27cp@chr13:105412781..105412798, +
6.21e-65FFCP PHASE1:Mm9::chr5:123465955..123465966,-#_ea38d4afafa4ec5d602175dd55fde27cp@chr5:123465955..123465966, -
6.21e-65FFCP PHASE2:Mm9::chr13:105412781..105412798,+#_ea38d4afafa4ec5d602175dd55fde27cp@chr13:105412781..105412798, +
1.0e-60FFCP PHASE1:Mm9::chr2:11097490..11097500,+#_6104f64cf17f5fef55f09acb519d1238p@chr2:11097490..11097500, +
1.0e-60FFCP PHASE2:Mm9::chr2:11097490..11097500,+#_6104f64cf17f5fef55f09acb519d1238p@chr2:11097490..11097500, +
1.33e-60FFCP PHASE1:Mm9::chr12:70398221..70398232,-#_b2a139c39c0d548e974ee07c541fb2a0p@chr12:70398221..70398232, -
1.33e-60FFCP PHASE2:Mm9::chr12:70398221..70398232,-#_b2a139c39c0d548e974ee07c541fb2a0p@chr12:70398221..70398232, -
1.33e-60FFCP PHASE2:Mm9::chr7:150943007..150943022,+#_b2a139c39c0d548e974ee07c541fb2a0p@chr7:150943007..150943022, +
1.33e-60FFCP PHASE1:Mm9::chr5:108160486..108160515,-#_b2a139c39c0d548e974ee07c541fb2a0p@chr5:108160486..108160515, -
1.33e-60FFCP PHASE1:Mm9::chr10:128157769..128157772,-#_b2a139c39c0d548e974ee07c541fb2a0p@chr10:128157769..128157772, -
1.33e-60FFCP PHASE2:Mm9::chr10:128157769..128157772,-#_b2a139c39c0d548e974ee07c541fb2a0p@chr10:128157769..128157772, -
1.33e-60FFCP PHASE1:Mm9::chr7:150943007..150943022,+#_b2a139c39c0d548e974ee07c541fb2a0p@chr7:150943007..150943022, +
1.33e-60FFCP PHASE2:Mm9::chr5:108160486..108160515,-#_b2a139c39c0d548e974ee07c541fb2a0p@chr5:108160486..108160515, -
1.77e-60FFCP PHASE2:Mm9::chr14:53414758..53414769,+#_2b6d2f8bea8f56bd75607128e7b0d9dep1@ENSMUST00000103582
1.77e-60FFCP PHASE1:Mm9::chr14:53414758..53414769,+#_2b6d2f8bea8f56bd75607128e7b0d9dep1@ENSMUST00000103582
2.34e-60FFCP PHASE1:Mm9::chr2:73290853..73290866,+#_a03fa8119b12fb002b6726c2b68d45adp@chr2:73290853..73290866, +
2.34e-60FFCP PHASE2:Mm9::chr2:73290853..73290866,+#_a03fa8119b12fb002b6726c2b68d45adp@chr2:73290853..73290866, +
4.1e-60FFCP PHASE1:Mm9::chr2:11181142..11181148,-#_5f58d1e2e8c18b0680cd6f12113f3321p@chr2:11181142..11181148, -
4.1e-60FFCP PHASE2:Mm9::chr1:138476217..138476228,+#_5f58d1e2e8c18b0680cd6f12113f3321p@chr1:138476217..138476228, +
4.1e-60FFCP PHASE2:Mm9::chr9:14708434..14708444,-#_5f58d1e2e8c18b0680cd6f12113f3321p8@Folr4
4.1e-60FFCP PHASE1:Mm9::chr9:14708434..14708444,-#_5f58d1e2e8c18b0680cd6f12113f3321p8@Folr4
4.1e-60FFCP PHASE1:Mm9::chr1:138476217..138476228,+#_5f58d1e2e8c18b0680cd6f12113f3321p@chr1:138476217..138476228, +
4.1e-60FFCP PHASE2:Mm9::chr2:11181142..11181148,-#_5f58d1e2e8c18b0680cd6f12113f3321p@chr2:11181142..11181148, -
6.9e-59FFCP PHASE1:Mm9::chrX:54477240..54477286,+#_f74be00bdd5507d916edec5381e96dd2p@chrX:54477240..54477286, +
6.9e-59FFCP PHASE2:Mm9::chr11:87558695..87558707,+#_f74be00bdd5507d916edec5381e96dd2p@chr11:87558695..87558707, +
6.9e-59FFCP PHASE2:Mm9::chrX:54465221..54465232,+#_f74be00bdd5507d916edec5381e96dd2p4@Cd40lg
6.9e-59FFCP PHASE1:Mm9::chr11:87558695..87558707,+#_f74be00bdd5507d916edec5381e96dd2p@chr11:87558695..87558707, +
6.9e-59FFCP PHASE2:Mm9::chrX:54477240..54477286,+#_f74be00bdd5507d916edec5381e96dd2p@chrX:54477240..54477286, +
6.9e-59FFCP PHASE1:Mm9::chrX:54465221..54465232,+#_f74be00bdd5507d916edec5381e96dd2p4@Cd40lg
1.09e-58FFCP PHASE2:Mm9::chr4:32339235..32339263,+#_e5984f712c9f39211b99983179ccadf9p@chr4:32339235..32339263, +
1.09e-58FFCP PHASE1:Mm9::chr4:32339235..32339263,+#_e5984f712c9f39211b99983179ccadf9p@chr4:32339235..32339263, +
1.71e-58FFCP PHASE1:Mm9::chr19:10904395..10904400,-#_c625a66ae66633eeaf1425fe9ed7d93cp5@Cd6
1.71e-58FFCP PHASE2:Mm9::chr19:10904395..10904400,-#_c625a66ae66633eeaf1425fe9ed7d93cp5@Cd6
1.71e-58FFCP PHASE2:Mm9::chr16:23175296..23175310,+#_c625a66ae66633eeaf1425fe9ed7d93cp3@uc007ytl.1
1.71e-58FFCP PHASE1:Mm9::chr16:23175296..23175310,+#_c625a66ae66633eeaf1425fe9ed7d93cp3@uc007ytl.1
2.15e-58FFCP PHASE2:Mm9::chr14:54831123..54831141,+#_36132390cb85b423d4ca9a91f31a3e04p1@ENSMUST00000103733
2.15e-58FFCP PHASE1:Mm9::chr14:54831123..54831141,+#_36132390cb85b423d4ca9a91f31a3e04p1@ENSMUST00000103733
2.69e-58FFCP PHASE1:Mm9::chr4:32339511..32339518,+#_2e13774566e3e15611b49486d860edc7p@chr4:32339511..32339518, +
2.69e-58FFCP PHASE2:Mm9::chr4:151490126..151490137,+#_2e13774566e3e15611b49486d860edc7p3@Tnfrsf25
2.69e-58FFCP PHASE1:Mm9::chr4:151490126..151490137,+#_2e13774566e3e15611b49486d860edc7p3@Tnfrsf25
2.69e-58FFCP PHASE2:Mm9::chr4:32339511..32339518,+#_2e13774566e3e15611b49486d860edc7p@chr4:32339511..32339518, +
3.38e-58FFCP PHASE2:Mm9::chr6:48656532..48656548,+#_cc30ac3f595085be0999a6a275a6008ep@chr6:48656532..48656548, +
3.38e-58FFCP PHASE1:Mm9::chr6:48656532..48656548,+#_cc30ac3f595085be0999a6a275a6008ep@chr6:48656532..48656548, +
3.91e-58FFCP PHASE1:Mm9::chr11:33948971..33948984,+#_0478b88129db921877fdf5e45c7bb6d0p@chr11:33948971..33948984, +
3.91e-58FFCP PHASE1:Mm9::chrX:54467216..54467227,+#_0478b88129db921877fdf5e45c7bb6d0p@chrX:54467216..54467227, +

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