Personal tools

Coexpression cluster:C4081: Difference between revisions

From FANTOM5_SSTAR

Jump to: navigation, search
No edit summary
No edit summary
Line 5: Line 5:
|ontology_enrichment_disease=DOID:1240!5.68e-10!39;DOID:2531!6.69e-08!51;DOID:0060083!6.69e-08!51;DOID:8692!2.16e-07!31
|ontology_enrichment_disease=DOID:1240!5.68e-10!39;DOID:2531!6.69e-08!51;DOID:0060083!6.69e-08!51;DOID:8692!2.16e-07!31
|ontology_enrichment_uberon=UBERON:0007023!3.72e-42!115;UBERON:0002390!2.86e-41!102;UBERON:0003061!2.86e-41!102;UBERON:0002193!1.13e-36!112;UBERON:0002371!9.40e-34!80;UBERON:0001474!2.63e-29!86;UBERON:0002405!1.21e-25!115;UBERON:0004765!3.69e-22!101;UBERON:0001434!3.69e-22!101;UBERON:0001049!2.17e-14!57;UBERON:0005068!2.17e-14!57;UBERON:0006241!2.17e-14!57;UBERON:0007135!2.17e-14!57;UBERON:0003080!2.22e-11!42;UBERON:0002780!5.09e-11!41;UBERON:0001890!5.09e-11!41;UBERON:0006240!5.09e-11!41;UBERON:0002616!8.65e-11!59;UBERON:0003081!7.02e-10!216;UBERON:0002020!7.64e-09!34;UBERON:0003528!7.64e-09!34;UBERON:0001893!1.04e-08!34;UBERON:0002791!1.99e-08!33;UBERON:0001017!3.03e-08!82;UBERON:0003075!3.62e-08!86;UBERON:0007284!3.62e-08!86;UBERON:0000955!3.82e-08!69;UBERON:0006238!3.82e-08!69;UBERON:0005743!9.36e-08!86;UBERON:0001869!9.82e-08!32;UBERON:0002346!3.62e-07!90
|ontology_enrichment_uberon=UBERON:0007023!3.72e-42!115;UBERON:0002390!2.86e-41!102;UBERON:0003061!2.86e-41!102;UBERON:0002193!1.13e-36!112;UBERON:0002371!9.40e-34!80;UBERON:0001474!2.63e-29!86;UBERON:0002405!1.21e-25!115;UBERON:0004765!3.69e-22!101;UBERON:0001434!3.69e-22!101;UBERON:0001049!2.17e-14!57;UBERON:0005068!2.17e-14!57;UBERON:0006241!2.17e-14!57;UBERON:0007135!2.17e-14!57;UBERON:0003080!2.22e-11!42;UBERON:0002780!5.09e-11!41;UBERON:0001890!5.09e-11!41;UBERON:0006240!5.09e-11!41;UBERON:0002616!8.65e-11!59;UBERON:0003081!7.02e-10!216;UBERON:0002020!7.64e-09!34;UBERON:0003528!7.64e-09!34;UBERON:0001893!1.04e-08!34;UBERON:0002791!1.99e-08!33;UBERON:0001017!3.03e-08!82;UBERON:0003075!3.62e-08!86;UBERON:0007284!3.62e-08!86;UBERON:0000955!3.82e-08!69;UBERON:0006238!3.82e-08!69;UBERON:0005743!9.36e-08!86;UBERON:0001869!9.82e-08!32;UBERON:0002346!3.62e-07!90
|tfbs_overrepresentation=0.147255,0.0586687,0.35968,0.0477154,0.199763,0.0460856,0.0430074,0.414564,0.03272,0.0257057,0.139423,0.225367,0.188771,0.125978,0.148679,0.0619003,0.140982,0.0982016,0.0528514,0.108057,0.188635,0.132577,0.081977,0.00465244,0.0415721,0.215492,0.209392,0.0907212,0.143747,0.0933697,0.204953,0.114046,0.0180314,0.208242,0.0665252,0.0844722,0.688181,0.0429682,0.120351,0.0667043,0.0964797,0.0246116,0.140039,0.184019,0.120917,0.0362416,0.0380166,0.18151,0.111283,0.121201,0.154071,0.0541794,0.0701653,0.0929951,0.198787,0.0384161,0.107455,0.212709,0.0783235,0.105572,0.0294301,0.149417,0.108602,0.0759481,0.054569,0.0504887,0.352278,0.0600088,0.0860723,0.167053,0.378921,0.067678,0.089036,0.119383,0.00747605,0.0171177,0.0964936,0.0436945,0.0372495,0.00725252,0.0956287,0.226912,0.0425,0.114846,0.291327,0.251834,0.064341,0.209032,0.0693924,0.062747,0.0857568,0.0495878,0.0953825,0.0473737,0.0853887,0.115028,0.58489,0.153631,0.0927458,0.27413,0.0574857,0.276221,0.141874,0.0370665,0.219088,0.0409286,0.0669887,0.338096,0.144217,0.269326,0.182599,0.0339971,0.149552,0.0176855,0.101221,0.0337525,0.0203386,0.0566549,0.139021,0.0838393,0.16671,0.214708,0.140123,0.0857827,0.102368,0.176912,0.0906875,0.0147934,0.0843604,0.134932,0.0595773,0.0748346,0.0572164,0.0227861,0.125792,0.108101,0.0648644,0.0553359,0.0330399,0.00395526,0.022776,0.127606,0.0223702,0.155998,0.596561,0.0693171,0.0988228,0.0842275,0.0389418,0.120833,0.200647,0.143677,0.180712,0.0265818,0.0427088,0.117549,0.0747594,0.00239446,0.0516985,0.0337251,0.227719,0.0952829,0.116642,0.147788,0.273479,0.114283,0.0400322,0.127369,0.0403542,0.00660878,0.179689,0.137725,0.46397,0.0541353,0.0799324,0.090079,0.140334,0.181817,0.178449,0.0356339,0.158844,0.122474,0.0274061,0.115574,0.0737247,0.118847,0.183031,0.0401756,0.0828697,0.173562,0.107145,0.187297,0.122935,0.228812,0.112671,0.0470731,0.0782523,0.0602859,0.0676496,0.109673,0.0893019,0.060398,0.0308319,0.0606036,0.136451,0.259411,0.27358,0.15185,0.206299,0.178359,0.0458667,0.104357,0.121154,0.1129,0.312578,0.169057,0.164202,0.100942,0.062995,0.10299,0.14193,0.0119362,0.15606,0.161026,0.0738599,0.126611,0.138852,0.085973,0.060453,0.059896,0.569726,0.384785,0.0418404,0.0765029,0.0959204,0.0931946,0.0472272,0.263087,0.163502,0.214803,0.182472,0.348993,0.0983991,0.0830921,0.116283,0.136838,0.0815104,0.111647,0.372804,0.117027,0.159052,0.185164,0.185743,0.0980288,0.0980899,0.159674,0.107242,0.201859,0.0695832,0.582402,0.0619218,0.1751,0.163376,0.128096,0.0345133,0.0810678,0.0811639,0.0920653,0.118078,0.0755168,0.278352,0.063292,0.254773,0.446759,0.0865903,0.0380459,0.130174,0.584917,0.713218,0.782949,0.0821962,0.051522,0.00879988,0.807281,0.335423,0.629514,0.261553,0.446302,0.373681,0.309233,0.49143,0.330703,0.395854,0.329568,0.53472,0.615744,0.271958,0.292154,0.405773,0.39729,0.581713,0.230901,0.187251,0.0756284,0.181715,0.423979,0.109988,0.330894,0.218329,0.427027,0.376924,0.463191,0.647576,0.528324,0.520763,0.370782,0.415647,0.484505,0.253571,0.276829,0.301787,0.0291592,0.316882,0.223503,0.155672,0.603208,0.283727,0.314747,0.577664,0.291709,0.448095,0.576651,0.416816,0.292835,0.476744,0.115044,0.373868,0.57762,0.241757,0.18237,0.346458,0.248484,0.747852,0.275351,0.236471,0.185661,0.0684159,0.179399,0.270984,0.625945,0.503058,0.513852,0.522083,0.248634,0.281576,0.472384,0.163244,0.0670502,0.0730934,0.184794,0.596648,0.762864,0.581837,0.412837,0.305671,0.546839,0.191921,0.448039,0.218623,0.312808,0.695172,0.0451077,0.0747529,0.229003,0.650179,0.589326,0.50215,0.294698,0.34331,0.477304,0.289204,0.327108,0.683186,0.278044,0.807485,0.428671,0.228096,0.336314,0.19763,0.15631,0.567452,0.421464,0.48267,0.104399,0.516462,0.858756,0.335105,0.144809,0.145539,0.385517,0.376191,0.447325,0.459928,0.252232,0.152681,0.0465712,0.137098,0.259235,0.134788,0.0985856,0.0460163,0.293698,0.284593,0.343734,0.306556,0.305777,0.2348,0.503082,0.522888,0.284629,0.262537,0.359455,0.226257,0.405955,0.41707,0.363685,0.464871,0.753577,0.206222,0.00713629,0.284166,0.437176,0.269226,0.339277,0.552319,0.281425,0.141758,0.124432,0.520495,0.159617,0.238587,0.0799758,0.232251,0.189515,0.0891382,0.0595618,0.524997,0.625309,0.347298,0.182325,0.34988,0.475069,0.404569,0.6408,0.630264,0.316179,0.0697683,0.0556835,0.192544,0.0779981,0.0575676,0.144322,0.223391,0.203656,0.442884,0.441735,0.191777,0.111931,0.28934,0.0435386,0.303336,0.126478,0.134852,0.10689,0.273326,0.0627924,0.381386,0.0179103,0.303939,0.279795,0.390395,0.0464827,0.169603,0.114583,0.104559,0.0899537,0.0866966,0.15983,0.107111,0.0438639,0.00389058,0.123593,0.129156,0.210369,0.193675,0.346372,0.0499762,0.0828956,0.0666953,0.182185,0.111277,0.219383,0.332809,0.19559,0.132201,0.188694,0.0481795,0.199971,0.406014,0.127758,0.175785,0.184486,0.169234,0.0876426,0.0952322,0.0112557,0.222432,0.107043,0.275244,0.00481323,0.173708,0.141119,0.211595,0.0300692,0.131551,0.0445237,0.052362,0.208866,0.153187,0.0797897,0.0974211,0.160149,0.123526,0.0906475,0.0558058,0.28262,0.517717,0.137332,0.0145999,0.0656973,0.211746,0.220538,0.0801488,0.0757897,0.161801,0.193215,0.0549034,0.0779715,0.0561838,0.0417636,0.0345419,0.0388736,0.254674,0.170307,0.201033,0.0488949,0.174921,0.370421,0.0330727,0.348757,0.219556,0.0394698,0.0596469,0.419264,0.122476,0.108872,0.11002,0.26144,0.0286025,0.549354,0.144567,0.038848,0.0874516,0.0550279,0.144067,0.253693,0.217069,0.190048,0.131088,0.394069,0.237101,0.286988,0.0761239,0.172491,0.0818785,0.182701,0.335058,0.147698,0.141463,0.167267,0.140622,0.0889592,0.309588,0.28711,0.0473033,0.094881,0.445524,0.132886,0.0774373,0.109194,0.128564,0.131452,0.323837,0.448776,0.051838,0.0993999,0.0500365,0.061829,0.0755121,0.0936516,0.144075,0.0340203,0.0741807,0.0425274,0.739716,0.655293,0.21727,0.0465945,0.119215,0.192475,0.177967,0.547859,0.057571,0.047591,0.392974,0.0608699,0.175319,0.300597,0.0713214,0.223874,0.291114,0.0355833,0.125606,0.175094,0.911304,0.936279,0.206454,0.218192,0.108277,0.0673484,0.108748,0.0494066,0.0958493,0.205732,0.0755808,0.045654,0.110216,0.070276,0.226171,0.153469,0.0376916,0.0004316,0.0450031,0.0539144,0.114242,0.0929549,0.172425,0.104948,0.221645,0.057168,0.234298,0.0759837,0.286863,0.152372,0.194941,0.218271,0.101607,0.327067,0.172982,0.340936,0.151597,0.0626744,0.191335,0.148574,0.504592,0.155821,0.0718905,0.0919008,0.0602373,0.144304,0.15063,0.0973823,0.15503,0.170295,0.193653,0.137219,0.228144,0.251466,0.288096,0.11903,0.0838874,0.331451,0.113145,0.112651,0.186638,0.174776,0.0948451,0.264079,0.249049,0.140533,0.0997756,0.257598,0.103667,0.113069,0.025556,0.16791,0.09066,0.585505,0.166967,0.188651,0.0813902,0.184948,0.156261,0.311847,0.511859,0.0590944,0.247324,0.178389,0.218229,0.231073,0.407281,0.619906,0.0360851,0.412187,0.131093,0.0434602,0.133616,0.418146,0.36927,0.449036,0.407369,0.231447,0.544776,0.43956,0.37006,0.42622,0.120472,0.197484,0.396996,0.36145,0.406019,0.0129,0.580441,0.276075,0.432035,0.366326,0.390366,0.48809,0.50058,0.443185,0.522904,0.875915,0.871256,0.227104,0.518585,0.617852,0.38649,0.284625,0.504757,0.55194,0.729153,0.28907,0.164197,0.462688,0.287881,0.21103,0.478174,0.336276,0.468444,0.258219,0.446557,0.243383,0.442897,0.390974,0.73485,0.683217,0.161598,0.751174,0.0868402,0.496032,0.799185,0.37357,0.454657,0.477353,0.78384,0.399222,0.771991,0.0222555,0.200493,0.20558,0.300504,0.25656,0.425963,0.349197,0.383291,0.156104,0.141318,0.0168417,0.0961477,0.055627,0.354789,0.163828,0.0289012,0.120226,0.00486063,0.562405,0.0556238,0.181415,0.282286,0.78,0.616388,0.408413,0.516511,0.322213,0.656109,0.33942,0.0700181,0.387276,0.522605,0.802166,0.537348,0.222037,0.102227,0.416292,0.462712,0.734551,0.215157,0.204817,0.452428,0.138871,0.673493,0.000885521,0.19783,0.0833851,0.316453,0.48065,0.175199,0.332919,0.373557,0.523625,0.408861,0.365487,0.178743,0.39088,0.363192,0.236011,0.203486,0.273398,0.375787,0.4466,0.351067,0.275347,0.637444,0.305885,0.241132,0.371414,0.30666,0.303709,0.495883,0.386538,0.159081,0.250964,0.383276,0.457886,0.504711,0.220231,0.509064,0.020816,0.191517,0.463751,0.235208,0.307334,0.459728,0.283463,0.563586,0.472935,0.399569,0.273281,0.368095,0.275089,0.384593,0.138622,0.359231,0.339729,0.0209984,0.608187,0.387069,0.332774,0.52832,0.299887,0.634365,0.205413,0.17639,0.0779009,0.276869,0.022685,0.0337138,0.18966,0.258854,0.188263,0.0719199,0.264884,0.162568,0.19104,0.163057,0.219428,0.208013,0.0900729,0.0953646,0.166124,0.252184,0.378361,0.255516,0.20753,0.447185,0.179412,0.193601,0.220904,0.0269454,0.341681,0.310674,0.21801,0.198614,0.186804,0.123324,0.199468,0.0325925,0.0933115,0.12405,0.179889,0.226869,0.27872,0.0855609,0.131118,0.20837,0.247588,0.222339,0.0673329,0.20847,0.266544,0.113092,0.145701,0.229428,0.162145,0.228955,0.168748,0.0384949,0.0660995,0.0521984,0.0455518,0.268741,0.201602,0.350452,0.154941,0.120196,0.0986735,0.108462,0.0595618,0.21593,0.158479,0.220319,0.195218,0.124213,0.259632,0.30793,0.180606,0.159884,0.257294,0.150733,0.217112,0.123917,0.184317,0.185335,0.0723291,0.258496,0.261744,0.203781,0.21382,0.207559,0.141867,0.193031,0.249101,0.115972,0.224568,0.246105,0.173026,0.200432,0.139785,0.197112,0.240478,0.156465,0.13108,0.256963,0.222798,0.172134,0.176789,0.0969345,0.202137,0.310405,0.280943,0.218161,0.0822373,0.202065,0.106739,0.0536053,0.0537737,0.15113,0.078016,0.0407233,0.0537355,0.319922,0.261724,0.211332,0.187731,0.233626,0.189559,0.0812887,0.0981146,0.064145,0.121913,0.0638699,0.104603,0.0663259,0.0762523,0.128736,0.109171,0.04411,0.066952,0.089609,0.0367455,0.13497,0.204393,0.295769,0.286691,0.347036,0.141729,0.263159,0.255956,0.200105,0.227491,0.29837,0.253509,0.177664,0.28365,0.264413,0.131761,0.160658,0.206239,0.19924,0.28689,0.236464,0.325148,0.115817,0.218052,0.223831,0.11528,0.194982,0.190993,0.281727,0.283218,0.249955,0.164638,0.224257,0.0935776,0.327622,0.225752,0.207791,0.0958756,0.0859274,0.000648999,0.171683,0.158847,0.271275,0.071111,0.270604,0.101021,0.222548,0.175934,0.157274,0.215705,0.252796,0.205954,0.361435
}}
}}

Revision as of 19:43, 8 August 2012


Full id: C4081_granulocyte_Monocytederived_acute_Macrophage_CD14_Dendritic_biphenotypic



Phase1 CAGE Peaks

Hg19::chr21:45773460..45773487,+p3@TRPM2
Hg19::chr21:45773492..45773512,+p1@TRPM2
Hg19::chr21:45773515..45773524,+p5@TRPM2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen
hematopoietic stem cell2.34e-57172
angioblastic mesenchymal cell2.34e-57172
hematopoietic oligopotent progenitor cell1.89e-52165
hematopoietic multipotent progenitor cell1.89e-52165
hematopoietic cell4.95e-51182
leukocyte2.06e-49140
myeloid cell2.89e-46112
common myeloid progenitor2.89e-46112
nongranular leukocyte3.85e-42119
myeloid leukocyte8.11e-4276
hematopoietic lineage restricted progenitor cell1.93e-41124
granulocyte monocyte progenitor cell2.44e-3971
macrophage dendritic cell progenitor7.13e-3965
monopoietic cell1.45e-3763
monocyte1.45e-3763
monoblast1.45e-3763
promonocyte1.45e-3763
myeloid lineage restricted progenitor cell5.27e-3770
CD14-positive, CD16-negative classical monocyte3.85e-3142
classical monocyte1.13e-2745
lymphocyte3.06e-0753
common lymphoid progenitor3.06e-0753
mesenchymal cell5.65e-07358
lymphoid lineage restricted progenitor cell7.19e-0752
Uber Anatomy
Ontology termp-valuen
adult organism3.72e-42115
hematopoietic system2.86e-41102
blood island2.86e-41102
hemolymphoid system1.13e-36112
bone marrow9.40e-3480
bone element2.63e-2986
immune system1.21e-25115
skeletal element3.69e-22101
skeletal system3.69e-22101
neural tube2.17e-1457
neural rod2.17e-1457
future spinal cord2.17e-1457
neural keel2.17e-1457
anterior neural tube2.22e-1142
regional part of forebrain5.09e-1141
forebrain5.09e-1141
future forebrain5.09e-1141
regional part of brain8.65e-1159
lateral plate mesoderm7.02e-10216
gray matter7.64e-0934
brain grey matter7.64e-0934
telencephalon1.04e-0834
regional part of telencephalon1.99e-0833
central nervous system3.03e-0882
neural plate3.62e-0886
presumptive neural plate3.62e-0886
brain3.82e-0869
future brain3.82e-0869
cerebral hemisphere9.82e-0832
neurectoderm3.62e-0790
Disease
Ontology termp-valuen
leukemia5.68e-1039
hematologic cancer6.69e-0851
immune system cancer6.69e-0851
myeloid leukemia2.16e-0731


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.