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|gostat_on_coexpression_clusters=GO:0008253!5'-nucleotidase activity!0.0275670551604664!84618$GO:0008252!nucleotidase activity!0.0275670551604664!84618$GO:0000287!magnesium ion binding!0.0275670551604664!5214;84618$GO:0005829!cytosol!0.0275670551604664!5214;84618$GO:0005945!6-phosphofructokinase complex!0.0275670551604664!5214$GO:0003872!6-phosphofructokinase activity!0.0275670551604664!5214$GO:0007190!adenylate cyclase activation!0.0275670551604664!10486$GO:0031281!positive regulation of cyclase activity!0.0275670551604664!10486$GO:0051349!positive regulation of lyase activity!0.0275670551604664!10486$GO:0045762!positive regulation of adenylate cyclase activity!0.0275670551604664!10486$GO:0008443!phosphofructokinase activity!0.0275670551604664!5214$GO:0007163!establishment and/or maintenance of cell polarity!0.0275670551604664!10486$GO:0007189!G-protein signaling, adenylate cyclase activating pathway!0.0281659660913172!10486$GO:0030425!dendrite!0.0281659660913172!23109$GO:0045761!regulation of adenylate cyclase activity!0.0281659660913172!10486$GO:0031279!regulation of cyclase activity!0.0281659660913172!10486$GO:0051339!regulation of lyase activity!0.0281659660913172!10486$GO:0009116!nucleoside metabolic process!0.0329202640965178!84618$GO:0019200!carbohydrate kinase activity!0.0353750131089477!5214$GO:0043005!neuron projection!0.0449943136693105!23109$GO:0007188!G-protein signaling, coupled to cAMP nucleotide second messenger!0.0449943136693105!10486$GO:0019933!cAMP-mediated signaling!0.0449943136693105!10486
|gostat_on_coexpression_clusters=GO:0008253!5'-nucleotidase activity!0.0275670551604664!84618$GO:0008252!nucleotidase activity!0.0275670551604664!84618$GO:0000287!magnesium ion binding!0.0275670551604664!5214;84618$GO:0005829!cytosol!0.0275670551604664!5214;84618$GO:0005945!6-phosphofructokinase complex!0.0275670551604664!5214$GO:0003872!6-phosphofructokinase activity!0.0275670551604664!5214$GO:0007190!adenylate cyclase activation!0.0275670551604664!10486$GO:0031281!positive regulation of cyclase activity!0.0275670551604664!10486$GO:0051349!positive regulation of lyase activity!0.0275670551604664!10486$GO:0045762!positive regulation of adenylate cyclase activity!0.0275670551604664!10486$GO:0008443!phosphofructokinase activity!0.0275670551604664!5214$GO:0007163!establishment and/or maintenance of cell polarity!0.0275670551604664!10486$GO:0007189!G-protein signaling, adenylate cyclase activating pathway!0.0281659660913172!10486$GO:0030425!dendrite!0.0281659660913172!23109$GO:0045761!regulation of adenylate cyclase activity!0.0281659660913172!10486$GO:0031279!regulation of cyclase activity!0.0281659660913172!10486$GO:0051339!regulation of lyase activity!0.0281659660913172!10486$GO:0009116!nucleoside metabolic process!0.0329202640965178!84618$GO:0019200!carbohydrate kinase activity!0.0353750131089477!5214$GO:0043005!neuron projection!0.0449943136693105!23109$GO:0007188!G-protein signaling, coupled to cAMP nucleotide second messenger!0.0449943136693105!10486$GO:0019933!cAMP-mediated signaling!0.0449943136693105!10486
|id=C978
|id=C978
|ontology_enrichment_celltype=CL:0000055!2.09e-08!180
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0000475!2.62e-26!365;UBERON:0005743!4.65e-26!86;UBERON:0000073!1.92e-25!94;UBERON:0001016!1.92e-25!94;UBERON:0001017!1.81e-24!82;UBERON:0000033!5.37e-24!123;UBERON:0000955!1.43e-23!69;UBERON:0006238!1.43e-23!69;UBERON:0000481!2.55e-23!347;UBERON:0004121!5.11e-23!169;UBERON:0000153!1.03e-22!129;UBERON:0007811!1.03e-22!129;UBERON:0000924!3.69e-22!173;UBERON:0006601!3.69e-22!173;UBERON:0003075!8.07e-22!86;UBERON:0007284!8.07e-22!86;UBERON:0001049!3.51e-21!57;UBERON:0005068!3.51e-21!57;UBERON:0006241!3.51e-21!57;UBERON:0007135!3.51e-21!57;UBERON:0007023!7.66e-21!115;UBERON:0002616!1.35e-20!59;UBERON:0002346!2.04e-20!90;UBERON:0001869!1.40e-18!32;UBERON:0002780!3.27e-18!41;UBERON:0001890!3.27e-18!41;UBERON:0006240!3.27e-18!41;UBERON:0001893!3.89e-18!34;UBERON:0000468!5.38e-18!659;UBERON:0002020!6.66e-18!34;UBERON:0003528!6.66e-18!34;UBERON:0003080!8.36e-18!42;UBERON:0002791!1.86e-17!33;UBERON:0003056!8.02e-17!61;UBERON:0000477!1.47e-16!286;UBERON:0000483!2.34e-15!309;UBERON:0000119!3.60e-15!312;UBERON:0002619!7.59e-15!22;UBERON:0000956!8.27e-15!25;UBERON:0000203!8.27e-15!25;UBERON:0004111!1.23e-14!241;UBERON:0001950!1.35e-13!20;UBERON:0000467!1.62e-13!625;UBERON:0000480!3.25e-13!626;UBERON:0000025!5.77e-13!194;UBERON:0000062!3.50e-12!511;UBERON:0000064!4.61e-12!219;UBERON:0000922!2.94e-11!612;UBERON:0002050!2.07e-10!605;UBERON:0005423!2.07e-10!605;UBERON:0000923!3.75e-10!604;UBERON:0005291!3.75e-10!604;UBERON:0006598!3.75e-10!604;UBERON:0002532!3.75e-10!604
}}
}}

Revision as of 15:00, 21 May 2012


Full id: C978_skeletal_amygdala_insula_occipital_medial_frontal_cerebral



Phase1 CAGE Peaks

Hg19::chr10:3147130..3147141,+p14@PFKP
Hg19::chr12:49393148..49393164,-p1@DDN
Hg19::chr14:89757957..89757974,-p1@ENST00000557743
Hg19::chr1:162458011..162458031,-p@chr1:162458011..162458031
-
Hg19::chr1:162458051..162458067,-p@chr1:162458051..162458067
-
Hg19::chr1:40137922..40137962,-p2@NT5C1A
Hg19::chr6:17393807..17393833,+p2@CAP2
Hg19::chr6:17393888..17393954,+p1@CAP2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:00082535'-nucleotidase activity0.0275670551604664
GO:0008252nucleotidase activity0.0275670551604664
GO:0000287magnesium ion binding0.0275670551604664
GO:0005829cytosol0.0275670551604664
GO:00059456-phosphofructokinase complex0.0275670551604664
GO:00038726-phosphofructokinase activity0.0275670551604664
GO:0007190adenylate cyclase activation0.0275670551604664
GO:0031281positive regulation of cyclase activity0.0275670551604664
GO:0051349positive regulation of lyase activity0.0275670551604664
GO:0045762positive regulation of adenylate cyclase activity0.0275670551604664
GO:0008443phosphofructokinase activity0.0275670551604664
GO:0007163establishment and/or maintenance of cell polarity0.0275670551604664
GO:0007189G-protein signaling, adenylate cyclase activating pathway0.0281659660913172
GO:0030425dendrite0.0281659660913172
GO:0045761regulation of adenylate cyclase activity0.0281659660913172
GO:0031279regulation of cyclase activity0.0281659660913172
GO:0051339regulation of lyase activity0.0281659660913172
GO:0009116nucleoside metabolic process0.0329202640965178
GO:0019200carbohydrate kinase activity0.0353750131089477
GO:0043005neuron projection0.0449943136693105
GO:0007188G-protein signaling, coupled to cAMP nucleotide second messenger0.0449943136693105
GO:0019933cAMP-mediated signaling0.0449943136693105



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
non-terminally differentiated cell2.09e-08180
Uber Anatomy
Ontology termp-valuen
organism subdivision2.62e-26365
regional part of nervous system1.92e-2594
nervous system1.92e-2594
central nervous system1.81e-2482
head5.37e-24123
brain1.43e-2369
future brain1.43e-2369
multi-tissue structure2.55e-23347
ectoderm-derived structure5.11e-23169
anterior region of body1.03e-22129
craniocervical region1.03e-22129
ectoderm3.69e-22173
presumptive ectoderm3.69e-22173
neural plate8.07e-2286
presumptive neural plate8.07e-2286
neural tube3.51e-2157
neural rod3.51e-2157
future spinal cord3.51e-2157
neural keel3.51e-2157
adult organism7.66e-21115
regional part of brain1.35e-2059
neurectoderm2.04e-2090
cerebral hemisphere1.40e-1832
regional part of forebrain3.27e-1841
forebrain3.27e-1841
future forebrain3.27e-1841
telencephalon3.89e-1834
multi-cellular organism5.38e-18659
gray matter6.66e-1834
brain grey matter6.66e-1834
anterior neural tube8.36e-1842
regional part of telencephalon1.86e-1733
pre-chordal neural plate8.02e-1761
anatomical cluster1.47e-16286
epithelium2.34e-15309
cell layer3.60e-15312
regional part of cerebral cortex7.59e-1522
cerebral cortex8.27e-1525
pallium8.27e-1525
anatomical conduit1.23e-14241
neocortex1.35e-1320
anatomical system1.62e-13625
anatomical group3.25e-13626
tube5.77e-13194
organ3.50e-12511
organ part4.61e-12219
embryo2.94e-11612
embryonic structure2.07e-10605
developing anatomical structure2.07e-10605
germ layer3.75e-10604
embryonic tissue3.75e-10604
presumptive structure3.75e-10604
epiblast (generic)3.75e-10604


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.