FF:10711-109H9: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005056 | ||
| | |accession_numbers=CAGE;DRX007887;DRR008759;DRZ000184;DRZ001569;DRZ011534;DRZ012919 | ||
| | |ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0000014,UBERON:0002097,UBERON:0002199,UBERON:0002371,UBERON:0001474,UBERON:0002384,UBERON:0000479,UBERON:0000064,UBERON:0000062,UBERON:0004120,UBERON:0000061,UBERON:0000465,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0003102,UBERON:0004765,UBERON:0010317,UBERON:0002204,UBERON:0001434,UBERON:0002390,UBERON:0002193,UBERON:0002405,UBERON:0002416 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0000151,CL:0002320,CL:0002371,CL:0000766,CL:0000219,CL:0000054,CL:0000738,CL:0000255,CL:0002092,CL:0000137,CL:0000092 | |||
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:0060072,DOID:0060085,DOID:7,DOID:201,DOID:0060100,DOID:3165,DOID:0060121,DOID:200,DOID:2438,DOID:4305,DOID:4418 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100583,FF:0100372,FF:0100969,FF:0103765,FF:0103766 | |||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr12:66218255..66218304,+!p3@HMGA2!2.04!281.18!HMGA2;;chr12:66218598..66218645,+!p2@HMGA2!1.79!265.28!HMGA2;;chr12:66218212..66218244,+!p5@HMGA2!1.76!80.08!HMGA2;;chr12:66218183..66218209,+!p4@HMGA2!1.64!80.68!HMGA2;;chr2:223163706..223163730,-!p1@PAX3!1.56!35.57!PAX3;;chr12:66218378..66218401,+!p6@HMGA2!1.54!51.67!HMGA2;;chr14:29235961..29236008,+!p1@FOXG1!1.48!29.41!FOXG1;;chr12:66218836..66218888,+!p1@HMGA2!1.45!241.24!HMGA2;;chr12:66218443..66218461,+!p8@HMGA2!1.43!32.59!HMGA2;;chr8:23564065..23564087,-!p1@NKX2-6!1.31!19.47!NKX2-6;;chr12:66218469..66218477,+!p16@HMGA2!1.28!18.08!HMGA2;;chr12:66218420..66218439,+!p12@HMGA2!1.26!17.29!HMGA2;;chr12:66218573..66218596,+!p7@HMGA2!1.24!24.24!HMGA2;;chr12:66218003..66218018,+!p9@HMGA2!1.21!18.28!HMGA2;;chr11:65667884..65667895,-!p2@FOSL1!1.20!57.03!FOSL1;;chr19:9811125..9811144,-!p2@ZNF812!1.17!13.71!ZNF812;;chr2:200322654..200322707,-!p2@SATB2!1.15!18.88!SATB2;;chr15:83953397..83953425,-!p1@BNC1!1.14!14.70!BNC1;;chr20:55204351..55204377,+!p1@TFAP2C!1.13!16.10!TFAP2C;;chr12:66218152..66218174,+!p10@HMGA2!1.12!13.12!HMGA2;;chr12:66358080..66358094,+!p15@HMGA2!1.10!11.72!HMGA2;;chr6:10412600..10412637,-!p1@TFAP2A!1.08!18.68!TFAP2A;;chr14:29236269..29236285,+!p3@FOXG1!1.08!11.13!FOXG1;;chr16:86544113..86544145,+!p1@FOXF1!1.03!12.12!FOXF1;;chr19:42636586..42636607,-!p1@POU2F2!1.02!26.83!POU2F2;;chr12:66218904..66218913,+!p11@HMGA2!1.02!9.54!HMGA2;;chr12:66357214..66357233,+!p13@HMGA2!1.01!9.34!HMGA2;;chr6:29648890..29648944,-!p1@ZFP57!1.00!8.94!ZFP57;;chr11:65667846..65667868,-!p1@FOSL1!0.99!234.28!FOSL1;;chr11:65686802..65686818,+!p6@DRAP1!0.99!15.50!DRAP1;;chr19:9609272..9609297,-!p1@ZNF560!0.97!8.35!ZNF560;;chr17:35294075..35294102,+!p1@ENST00000559335!0.96!8.15!LHX1;;chr3:169381420..169381535,-!p1@MECOM!0.95!9.34!MECOM;;chrX:132352373..132352384,-!p1@TFDP3!0.94!7.75!TFDP3;;chr6:34204921..34204939,+!p3@HMGA1!0.90!219.98!HMGA1;;chr12:115121962..115121987,-!p1@TBX3!0.89!60.21!TBX3;;chr14:29236169..29236216,+!p6@FOXG1!0.89!6.76!FOXG1;;chr21:38071430..38071456,+!p1@SIM2!0.89!6.76!SIM2;;chr11:65686732..65686756,+!p2@DRAP1!0.87!28.61!DRAP1;;chr19:22235279..22235301,+!p1@ZNF257!0.87!12.52!ZNF257;;chr1:158985493..158985535,+!p4@IFI16!0.87!10.13!IFI16;;chr1:170633348..170633399,+!p2@PRRX1!0.87!8.94!PRRX1;;chr21:38071403..38071428,+!p2@SIM2!0.87!6.36!SIM2;;chr12:66218923..66218934,+!p14@HMGA2!0.87!6.36!HMGA2;;chr17:8027418..8027432,-!p1@HES7!0.87!6.36!HES7;;chr6:10415276..10415341,-!p2@TFAP2A!0.85!7.55!TFAP2A;;chr17:46682321..46682362,-!p1@HOXB6!0.85!6.16!HOXB6;;chr12:85673977..85674015,+!p1@ALX1!0.85!6.16!ALX1;;chr19:20188776..20188826,+!p1@ZNF90!0.84!16.69!ZNF90;;chr5:134369905..134369972,-!p1@PITX1!0.83!9.14!PITX1;;chr19:9811101..9811112,-!p3@ZNF812!0.83!5.76!ZNF812;;chr12:54410664..54410684,+!p1@HOXC4,p1@HOXC5,p1@HOXC6!0.83!5.76!HOXC5;;chr5:138609782..138609826,+!p5@MATR3!0.82!39.35!MATR3;;chr16:29818199..29818216,+!p11@MAZ!0.82!9.54!MAZ;;chr20:50179368..50179392,-!p2@NFATC2!0.82!7.35!NFATC2;;chr2:172949484..172949522,+!p1@DLX1!0.82!5.56!DLX1;;chr19:22034809..22034878,-!p2@ZNF43!0.81!20.27!ZNF43;;chr11:61520075..61520136,+!p1@C11orf9!0.81!12.12!C11orf9;;chr5:72744445..72744466,-!p2@FOXD1!0.81!9.54!FOXD1;;chr15:67418119..67418162,+!p5@SMAD3!0.81!6.16!SMAD3;;chr17:41623692..41623715,-!p1@ETV4!0.80!24.64!ETV4;;chr17:41622925..41622976,-!p3@ETV4!0.80!8.15!ETV4;;chr17:46687959..46688007,-!p2@HOXB7!0.80!7.55!HOXB7;;chr12:2986206..2986258,-!p2@FOXM1!0.79!34.18!FOXM1;;chr20:42543441..42543497,+!p1@TOX2!0.79!25.04!TOX2;;chr8:106330656..106330684,+!p1@ZFPM2!0.79!14.51!ZFPM2;;chr6:10412392..10412409,-!p4@TFAP2A!0.79!5.96!TFAP2A;;chr12:2986275..2986363,-!p1@FOXM1!0.78!55.64!FOXM1;;chr11:65687222..65687240,+!p7@DRAP1!0.78!6.56!DRAP1;;chr5:176738887..176738934,-!p1@MXD3!0.77!35.77!MXD3;;chr5:321810..321877,+!p1@AHRR!0.76!16.29!AHRR;;chr12:66218413..66218418,+!p17@HMGA2!0.76!4.77!HMGA2;;chr11:65687158..65687216,+!p4@DRAP1!0.75!29.21!DRAP1;;chr1:47779762..47779827,-!p1@STIL,p1@TAL1!0.75!23.05!TAL1;;chr2:185463247..185463263,+!p1@ZNF804A!0.75!8.74!ZNF804A;;chr17:46622229..46622257,-!p6@HOXB2!0.75!5.56!HOXB2;;chr19:22193731..22193751,-!p1@ZNF208!0.75!4.57!ZNF208;;chr4:109089095..109089144,-!p6@LEF1!0.75!4.57!LEF1;;chr12:77459306..77459365,-!p1@E2F7!0.74!62.40!E2F7;;chr15:67418047..67418093,+!p4@SMAD3!0.73!5.76!SMAD3;;chr1:158985469..158985489,+!p7@IFI16!0.73!5.37!IFI16;;chr7:26191809..26191890,+!p1@NFE2L3!0.72!23.65!NFE2L3;;chr5:72744594..72744609,-!p1@FOXD1!0.72!21.46!FOXD1;;chr17:41277372..41277418,-!p1@BRCA1!0.72!16.89!BRCA1;;chr7:19157248..19157268,-!p1@TWIST1!0.71!12.52!TWIST1;;chr14:35872962..35873025,-!p3@NFKBIA!0.71!11.53!NFKBIA;;chr2:200323414..200323455,-!p1@SATB2!0.71!9.54!SATB2;;chr19:24097706..24097731,+!p2@ZNF726!0.71!8.54!ZNF726;;chr12:27485762..27485776,+!p3@ARNTL2!0.70!11.92!ARNTL2;;chr20:42543506..42543549,+!p2@TOX2!0.70!10.53!TOX2;;chr4:81118647..81118666,+!p1@PRDM8!0.70!5.56!PRDM8;;chr11:120107344..120107351,+!p1@POU2F3!0.70!4.97!POU2F3;;chr1:170632285..170632309,+!p1@PRRX1!0.70!4.57!PRRX1;;chr11:65687362..65687436,+!p3@DRAP1!0.69!19.87!DRAP1;;chr15:96875657..96875760,+!p14@NR2F2!0.69!6.76!NR2F2;;chr14:75988771..75988826,+!p1@BATF!0.69!5.37!BATF;;chr6:31126291..31126399,+!p1@TCF19!0.68!40.94!TCF19;;chr11:65687243..65687276,+!p8@DRAP1!0.68!5.37!DRAP1;;chr11:34642612..34642646,+!p1@EHF!0.68!3.78!EHF;;chr7:27196267..27196311,-!p1@HOXA7!0.68!3.78!HOXA7;;chr4:53206..53260,+!p1@ZNF595,p1@ZNF718!0.67!40.74!ZNF595;;chr12:27485785..27485816,+!p1@ARNTL2!0.67!29.01!ARNTL2;;chr2:60780753..60780800,-!p1@BCL11A!0.67!20.47!BCL11A;;chr6:20402102..20402152,+!p1@E2F3!0.67!17.29!E2F3;;chr8:23540441..23540466,-!p1@NKX3-1!0.67!7.95!NKX3-1;;chr17:46688334..46688385,-!p1@HOXB7!0.67!5.56!HOXB7;;chr10:35484804..35484902,+!p2@CREM!0.66!15.50!CREM;;chr7:19157043..19157088,-!p2@TWIST1!0.66!9.94!TWIST1;;chr1:45805872..45805900,+!p2@TOE1!0.66!9.54!TOE1;;chr12:54447599..54447630,+!p3@HOXC4!0.66!4.57!HOXC4;;chr12:115122318..115122331,-!p2@TBX3!0.66!3.58!TBX3;;chr16:29818160..29818188,+!p6@MAZ!0.65!18.68!MAZ;;chr2:239756739..239756755,+!p2@TWIST2!0.65!6.36!TWIST2;;chr11:6947720..6947812,+!p1@ZNF215!0.65!4.77!ZNF215;;chr17:41622765..41622821,-!p2@ETV4!0.64!5.56!ETV4;;chr1:120190786..120190915,-!p1@ZNF697!0.63!27.62!ZNF697;;chr19:22817119..22817145,+!p1@ZNF492!0.63!5.96!ZNF492;;chr10:44070016..44070069,-!p1@ZNF239!0.62!10.93!ZNF239;;chr1:59249645..59249656,-!p4@JUN!0.62!8.94!JUN;;chr11:32457103..32457123,-!p3@WT1!0.62!3.18!WT1;;chr12:54394309..54394336,+!p2@HOXC9!0.62!3.18!HOXC9;;chr15:67418177..67418204,+!p9@SMAD3!0.62!3.18!SMAD3;;chr3:157823517..157823562,-!p1@SHOX2!0.61!3.38!SHOX2;;chr12:7079780..7079791,-!p2@PHB2!0.60!18.48!PHB2;;chr19:23433144..23433204,-!p1@ZNF724P!0.60!15.90!ZNF724P;;chr19:12203100..12203132,+!p1@ZNF788!0.60!6.76!ZNF788;;chr6:28973090..28973094,-!p1@ZNF311!0.60!3.97!ZNF311;;chr2:172967353..172967365,-!p5@DLX2!0.60!2.98!DLX2;;chr9:4300050..4300118,-!p1@GLIS3!0.59!22.65!GLIS3;;chr2:60780607..60780624,-!p2@BCL11A!0.59!10.33!BCL11A;;chr1:170633262..170633285,+!p3@PRRX1!0.59!3.38!PRRX1;;chr2:172967621..172967637,-!p1@DLX2!0.58!8.74!DLX2;;chr12:3068466..3068495,+!p3@TEAD4!0.58!6.96!TEAD4;;chr17:46622205..46622218,-!p3@HOXB2!0.58!3.38!HOXB2;;chr17:46622440..46622477,-!p5@HOXB2!0.58!3.18!HOXB2;;chr2:172967276..172967296,-!p3@DLX2!0.58!2.78!DLX2;;chr6:10415484..10415508,-!p3@TFAP2A!0.58!2.78!TFAP2A;;chr11:57103327..57103372,-!p1@SSRP1!0.57!159.57!SSRP1;;chr6:34204973..34204990,+!p4@HMGA1!0.57!45.31!HMGA1;;chr5:133450365..133450444,+!p1@TCF7!0.57!14.90!TCF7;;chr2:101436564..101436647,+!p1@NPAS2!0.56!66.77!NPAS2;;chr11:65686952..65686975,+!p5@DRAP1!0.56!17.88!DRAP1;;chr8:106330696..106330719,+!p2@ZFPM2!0.56!3.58!ZFPM2;;chr20:32274179..32274213,-!p1@E2F1!0.55!20.87!E2F1;;chr12:3068501..3068515,+!p4@TEAD4!0.55!4.97!TEAD4;;chr12:54447637..54447659,+!p4@HOXC4!0.55!2.58!HOXC4;;chr7:27153454..27153469,-!p2@HOXA3!0.55!2.58!HOXA3;;chr19:22605136..22605154,-!p1@ZNF98!0.55!2.58!ZNF98;;chr4:188916918..188916942,+!p1@ZFP42!0.55!2.58!ZFP42;;chr6:34204672..34204692,+!p1@HMGA1!0.54!353.91!HMGA1;;chr17:41622834..41622883,-!p6@ETV4!0.54!3.18!ETV4;;chr3:71114066..71114114,-!p1@FOXP1!0.53!63.19!FOXP1;;chr20:48809000..48809053,+!p12@CEBPB!0.53!3.38!CEBPB;;chr17:46806067..46806097,-!p1@HOXB13!0.53!2.38!HOXB13;;chr13:100634031..100634045,+!p1@ZIC2!0.53!2.38!ZIC2;;chr3:147111198..147111225,+!p4@ZIC1!0.53!2.38!ZIC1;;chr6:34210478..34210481,+!p8@HMGA1!0.53!2.38!HMGA1;;chr7:27169801..27169844,-!p2@HOXA4!0.53!2.38!HOXA4;;chr7:96634850..96634874,+!p3@DLX6!0.53!2.38!DLX6;;chr20:30193083..30193098,+!p1@ID1!0.52!246.41!ID1;;chr12:26277956..26277980,-!p1@BHLHE41!0.52!10.33!BHLHE41;;chr8:145669791..145669834,-!p1@TONSL!0.52!8.15!TONSL;;chr5:150284532..150284549,-!p1@ZNF300!0.52!5.56!ZNF300;;chr19:23299814..23299844,+!p1@ZNF730!0.52!2.98!ZNF730;;chr12:19592405..19592492,+!p2@AEBP2!0.51!24.64!AEBP2;;chr5:72743793..72743855,-!p4@FOXD1!0.51!2.78!FOXD1;;chr12:48298785..48298828,-!p1@VDR!0.50!14.90!VDR;;chr2:239756671..239756732,+!p1@TWIST2!0.50!8.74!TWIST2;;chr20:32274150..32274166,-!p2@E2F1!0.50!4.77!E2F1;;chr1:247171347..247171366,-!p2@ZNF695!0.50!4.57!ZNF695;;chr15:57511609..57511651,+!p2@TCF12!0.50!4.17!TCF12;;chr17:41623009..41623053,-!p4@ETV4!0.50!3.97!ETV4;;chr17:46687935..46687950,-!p3@HOXB7!0.50!2.19!HOXB7;;chr5:134369879..134369898,-!p2@PITX1!0.50!2.19!PITX1;;chr5:50679228..50679288,+!p1@ISL1!0.50!2.19!ISL1;;chr2:113999263..113999274,-!p13@PAX8!0.50!2.19!PAX8;;chr3:25470062..25470084,+!p4@RARB!0.50!2.19!RARB;;chr11:31832658..31832681,-!p1@PAX6!0.50!2.19!PAX6;;chr12:54393880..54393962,+!p1@HOXC9!0.50!2.19!HOXC9;;chr13:100634004..100634025,+!p2@ZIC2!0.50!2.19!ZIC2;;chr14:29236301..29236317,+!p5@FOXG1!0.50!2.19!FOXG1;;chr12:3068544..3068597,+!p1@TEAD4!0.49!16.49!TEAD4;;chr6:34205372..34205412,+!p5@HMGA1!0.49!13.71!HMGA1;;chr8:77593474..77593612,+!p1@ZFHX4!0.49!11.33!ZFHX4;;chr7:42276787..42276815,-!p1@GLI3!0.49!6.96!GLI3;;chr5:138647473..138647476,+!p6@MATR3!0.49!6.56!MATR3;;chr12:48298765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| |||
|ffid_belonging_in_development=CL:0000049,CL:0000134,CL:0000335,UBERON:0002532,UBERON:0006603,UBERON:0010316 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |||
| | |||
|fonse_cell_line=FF:0100583,FF:0103765 | |fonse_cell_line=FF:0100583,FF:0103765 | ||
|fonse_cell_line_closure=FF:0100583,FF:0103765 | |fonse_cell_line_closure=FF:0100583,FF:0103765 | ||
Line 66: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|top_motifs= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/fibrous%2520histiocytoma%2520cell%2520line%253aGCT%2520TIB-223.CNhs11842.10711-109H9.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/fibrous%2520histiocytoma%2520cell%2520line%253aGCT%2520TIB-223.CNhs11842.10711-109H9.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/fibrous%2520histiocytoma%2520cell%2520line%253aGCT%2520TIB-223.CNhs11842.10711-109H9.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/fibrous%2520histiocytoma%2520cell%2520line%253aGCT%2520TIB-223.CNhs11842.10711-109H9.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/fibrous%2520histiocytoma%2520cell%2520line%253aGCT%2520TIB-223.CNhs11842.10711-109H9.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10711-109H9 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0103766 | |||
|is_obsolete= | |||
|library_id=CNhs11842 | |||
|library_id_phase_based=2:CNhs11842 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10711 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10711 | |||
|name=fibrous histiocytoma cell line:GCT TIB-223 | |||
|namespace=FANTOM5 | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs11842,LSID829,release010,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,-0.0149882089931272,0,-0.0233319289686302,0.155318092416473,0,0,0,0,0,0,0,0,0,0,0,0.078715799182705,0,0.146309145540884,0,0,0,0.0393578995913525,0,-0.0192420970853526,0,0,0.166675566110449,0,0,0,0,0,0,0,0,0,0,0.078715799182705,0,-0.0646057434843514,0,0,0,0,0,0,0,0,-0.0242150211128343,0,0,0,0,0,0,0.078715799182705,0.157037841982279,0,0,-0.018627828030392,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0393578995913525,0,0,0,0,0,0,0,0,0,-0.0584468268118252,-0.00139073244309074,0,0,0.0393578995913525,0.078715799182705,-0.0193195520550015,0.227810904576807,0,0,0,0,0,0,0,0,0,0,0.254030203224884,0,0,0,0,0,0,-0.096373593922461,0.254030203224884,0,0,-0.0133121660657801,-0.271524318836707,0,0,0.0953471419062993,0,0,0.145329821093259 | |||
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| |||
|rna_box=109 | |||
|rna_catalog_number= | |||
|rna_concentration=1.28128 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.17 | |||
|rna_od260/280=2.09 | |||
|rna_position=H9 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=109H9 | |||
|rna_weight_ug=60.22016 | |||
|sample_age=29 | |||
|sample_category=cell lines | |||
|sample_cell_catalog=TIB-223 | |||
|sample_cell_line=GCT TIB-223 | |||
|sample_cell_lot= | |||
|sample_cell_type=unclassifiable | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=ATCC | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=fibrous histiocytoma | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.81017699416886e-276!GO:0043227;membrane-bound organelle;2.69400962917934e-230!GO:0043231;intracellular membrane-bound organelle;2.69400962917934e-230!GO:0043226;organelle;3.96397479318549e-230!GO:0043229;intracellular organelle;2.03174766023183e-229!GO:0005737;cytoplasm;8.09084174095754e-174!GO:0044422;organelle part;3.74232608658832e-169!GO:0044446;intracellular organelle part;2.83187084663239e-167!GO:0032991;macromolecular complex;1.07863951181493e-127!GO:0005634;nucleus;1.11600607058596e-118!GO:0044444;cytoplasmic part;1.18158889455081e-118!GO:0044237;cellular metabolic process;3.01283971455861e-109!GO:0030529;ribonucleoprotein complex;1.84056586426924e-107!GO:0043170;macromolecule metabolic process;2.62162773578508e-107!GO:0044238;primary metabolic process;2.91345271964092e-107!GO:0044428;nuclear part;1.88749678217413e-102!GO:0043233;organelle lumen;3.92529193499939e-91!GO:0031974;membrane-enclosed lumen;3.92529193499939e-91!GO:0003723;RNA binding;1.57094219391944e-88!GO:0005515;protein binding;5.43667645185056e-78!GO:0043283;biopolymer metabolic process;1.15453772814694e-68!GO:0005739;mitochondrion;1.52256158713738e-68!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.33048200462171e-64!GO:0043234;protein complex;6.13316979066098e-64!GO:0006396;RNA processing;4.88569346827245e-63!GO:0005840;ribosome;8.42983793171598e-63!GO:0006412;translation;8.70379606516791e-63!GO:0010467;gene expression;2.23111084103212e-62!GO:0031981;nuclear lumen;2.1248252748343e-61!GO:0016043;cellular component organization and biogenesis;2.51931482258369e-58!GO:0003735;structural constituent of ribosome;6.0918253576456e-55!GO:0019538;protein metabolic process;2.39833398062288e-54!GO:0044267;cellular protein metabolic process;1.05901741519226e-48!GO:0044260;cellular macromolecule metabolic process;4.17340378848885e-48!GO:0006259;DNA metabolic process;3.14007609610007e-47!GO:0031090;organelle membrane;1.44900629034906e-46!GO:0043228;non-membrane-bound organelle;3.23797845533441e-46!GO:0043232;intracellular non-membrane-bound organelle;3.23797845533441e-46!GO:0016071;mRNA metabolic process;2.37959190741187e-45!GO:0033279;ribosomal subunit;2.45041065459547e-45!GO:0044429;mitochondrial part;8.12391513936292e-45!GO:0009059;macromolecule biosynthetic process;1.7973077647286e-44!GO:0031967;organelle envelope;2.80412521488837e-44!GO:0044249;cellular biosynthetic process;3.01619405789081e-44!GO:0033036;macromolecule localization;4.10859183007986e-44!GO:0015031;protein transport;4.75430043609089e-44!GO:0031975;envelope;7.02012817139077e-44!GO:0006996;organelle organization and biogenesis;1.2235098616109e-43!GO:0008380;RNA splicing;3.38506859868692e-43!GO:0003676;nucleic acid binding;4.55516313102236e-42!GO:0009058;biosynthetic process;7.12913378474458e-41!GO:0045184;establishment of protein localization;1.31405651553877e-40!GO:0008104;protein localization;3.51716048486407e-40!GO:0006397;mRNA processing;9.57298358208242e-40!GO:0065003;macromolecular complex assembly;7.45898382051219e-39!GO:0046907;intracellular transport;9.5478906713245e-39!GO:0022613;ribonucleoprotein complex biogenesis and assembly;2.23189062950423e-38!GO:0005829;cytosol;2.51920243774294e-38!GO:0005654;nucleoplasm;3.359783895991e-37!GO:0007049;cell cycle;4.24520347080729e-37!GO:0022607;cellular component assembly;1.66777790725379e-34!GO:0005681;spliceosome;6.32085456940035e-32!GO:0006886;intracellular protein transport;1.99153438432934e-31!GO:0005830;cytosolic ribosome (sensu Eukaryota);3.17885575431419e-31!GO:0044451;nucleoplasm part;1.30383372535479e-30!GO:0016070;RNA metabolic process;4.35768500606886e-30!GO:0000278;mitotic cell cycle;7.00477261512682e-29!GO:0000166;nucleotide binding;1.61627313829965e-28!GO:0022402;cell cycle process;2.09877869481842e-28!GO:0005740;mitochondrial envelope;4.69619116048491e-28!GO:0005694;chromosome;1.38303440175609e-27!GO:0051649;establishment of cellular localization;9.58294740113722e-27!GO:0051641;cellular localization;1.87200374748337e-26!GO:0031966;mitochondrial membrane;2.5219089852798e-26!GO:0019866;organelle inner membrane;4.99312034208461e-26!GO:0044427;chromosomal part;1.92789479419517e-25!GO:0005730;nucleolus;2.69392092520566e-25!GO:0006974;response to DNA damage stimulus;2.69392092520566e-25!GO:0015934;large ribosomal subunit;7.35875625910821e-25!GO:0044445;cytosolic part;8.63007737229885e-25!GO:0005743;mitochondrial inner membrane;9.28292150658916e-24!GO:0006119;oxidative phosphorylation;1.88137850745423e-23!GO:0022403;cell cycle phase;2.63757628788122e-23!GO:0000087;M phase of mitotic cell cycle;3.475921649991e-23!GO:0016462;pyrophosphatase activity;5.87987332515412e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;7.48831296416388e-23!GO:0007067;mitosis;8.85625967936698e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;1.26121133235827e-22!GO:0017111;nucleoside-triphosphatase activity;1.86678200436955e-22!GO:0006281;DNA repair;1.95630678453605e-22!GO:0051276;chromosome organization and biogenesis;1.16731455987162e-21!GO:0015935;small ribosomal subunit;1.18150836170674e-21!GO:0022618;protein-RNA complex assembly;1.68316020537014e-21!GO:0044455;mitochondrial membrane part;2.3148371957194e-21!GO:0006457;protein folding;6.06176948005023e-21!GO:0006260;DNA replication;9.48900364930665e-21!GO:0000279;M phase;1.40784900148904e-20!GO:0016874;ligase activity;7.92776603003327e-20!GO:0031980;mitochondrial lumen;1.28621317081137e-19!GO:0005759;mitochondrial matrix;1.28621317081137e-19!GO:0006512;ubiquitin cycle;1.44358864659282e-19!GO:0032553;ribonucleotide binding;1.907855280182e-19!GO:0032555;purine ribonucleotide binding;1.907855280182e-19!GO:0051603;proteolysis involved in cellular protein catabolic process;2.56922579914318e-19!GO:0017076;purine nucleotide binding;2.65711726457878e-19!GO:0043285;biopolymer catabolic process;3.08270827318083e-19!GO:0019941;modification-dependent protein catabolic process;3.24776029442413e-19!GO:0043632;modification-dependent macromolecule catabolic process;3.24776029442413e-19!GO:0051301;cell division;3.45282654248591e-19!GO:0012505;endomembrane system;5.35750637560004e-19!GO:0044257;cellular protein catabolic process;5.55607775277496e-19!GO:0006511;ubiquitin-dependent protein catabolic process;6.28396622781386e-19!GO:0044265;cellular macromolecule catabolic process;1.95745937793865e-18!GO:0042254;ribosome biogenesis and assembly;2.13760607414319e-18!GO:0005746;mitochondrial respiratory chain;3.1271330791967e-18!GO:0000502;proteasome complex (sensu Eukaryota);3.22845045614162e-18!GO:0005761;mitochondrial ribosome;4.43019792784809e-18!GO:0000313;organellar ribosome;4.43019792784809e-18!GO:0030163;protein catabolic process;9.20836049506924e-18!GO:0008135;translation factor activity, nucleic acid binding;1.27738039949968e-17!GO:0005524;ATP binding;2.06527687697419e-17!GO:0006605;protein targeting;2.09826155551558e-17!GO:0008134;transcription factor binding;2.10286894423461e-17!GO:0009057;macromolecule catabolic process;2.83831926221525e-17!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;4.7461809030848e-17!GO:0032559;adenyl ribonucleotide binding;6.837055264592e-17!GO:0005635;nuclear envelope;7.31745991735585e-17!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.08553598329907e-16!GO:0030554;adenyl nucleotide binding;1.52977679443904e-16!GO:0044453;nuclear membrane part;3.31718819640027e-16!GO:0051082;unfolded protein binding;3.37081634557448e-16!GO:0009719;response to endogenous stimulus;4.24776891648416e-16!GO:0031965;nuclear membrane;4.38006635454426e-16!GO:0050136;NADH dehydrogenase (quinone) activity;4.3988153909235e-16!GO:0003954;NADH dehydrogenase activity;4.3988153909235e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;4.3988153909235e-16!GO:0000398;nuclear mRNA splicing, via spliceosome;5.93027553604338e-16!GO:0000375;RNA splicing, via transesterification reactions;5.93027553604338e-16!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;5.93027553604338e-16!GO:0048770;pigment granule;7.71792539746273e-16!GO:0042470;melanosome;7.71792539746273e-16!GO:0006325;establishment and/or maintenance of chromatin architecture;8.18845199245362e-16!GO:0006323;DNA packaging;3.63418149331133e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);8.36786122337135e-15!GO:0006399;tRNA metabolic process;1.47607568757862e-14!GO:0006913;nucleocytoplasmic transport;1.77864727786829e-14!GO:0044248;cellular catabolic process;2.06117606663885e-14!GO:0016604;nuclear body;2.40268679902968e-14!GO:0042775;organelle ATP synthesis coupled electron transport;2.58598727771699e-14!GO:0042773;ATP synthesis coupled electron transport;2.58598727771699e-14!GO:0051169;nuclear transport;4.37626471922067e-14!GO:0043412;biopolymer modification;4.65394300399818e-14!GO:0030964;NADH dehydrogenase complex (quinone);6.15977017899918e-14!GO:0045271;respiratory chain complex I;6.15977017899918e-14!GO:0005747;mitochondrial respiratory chain complex I;6.15977017899918e-14!GO:0051186;cofactor metabolic process;6.54857112764206e-14!GO:0005643;nuclear pore;8.02649988514429e-14!GO:0051726;regulation of cell cycle;1.525006326641e-13!GO:0048193;Golgi vesicle transport;1.73366825059086e-13!GO:0000074;regulation of progression through cell cycle;1.9322617101145e-13!GO:0016887;ATPase activity;1.94651913362045e-13!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;2.03691109509044e-13!GO:0012501;programmed cell death;2.27337636359508e-13!GO:0005783;endoplasmic reticulum;2.93003138427627e-13!GO:0006915;apoptosis;3.74506822283859e-13!GO:0003743;translation initiation factor activity;4.60632355361192e-13!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;4.67702398846016e-13!GO:0004386;helicase activity;4.89826303385223e-13!GO:0000785;chromatin;5.61938564524758e-13!GO:0065004;protein-DNA complex assembly;6.5034451988494e-13!GO:0006333;chromatin assembly or disassembly;7.47837719747496e-13!GO:0042623;ATPase activity, coupled;9.89552657363779e-13!GO:0006413;translational initiation;1.11879736922183e-12!GO:0006446;regulation of translational initiation;3.14593451542262e-12!GO:0044432;endoplasmic reticulum part;4.42737703016771e-12!GO:0006464;protein modification process;4.49725550935812e-12!GO:0008219;cell death;6.45768442692346e-12!GO:0016265;death;6.45768442692346e-12!GO:0006364;rRNA processing;6.57830761906042e-12!GO:0003712;transcription cofactor activity;1.17686691156277e-11!GO:0016072;rRNA metabolic process;2.01077151053483e-11!GO:0017038;protein import;2.04336139909438e-11!GO:0006366;transcription from RNA polymerase II promoter;2.18334958663465e-11!GO:0006403;RNA localization;2.50398177027614e-11!GO:0050794;regulation of cellular process;2.9461593480913e-11!GO:0065002;intracellular protein transport across a membrane;3.07395673093846e-11!GO:0050657;nucleic acid transport;3.18537404741369e-11!GO:0051236;establishment of RNA localization;3.18537404741369e-11!GO:0050658;RNA transport;3.18537404741369e-11!GO:0005794;Golgi apparatus;3.28434635019147e-11!GO:0046930;pore complex;4.02391302704904e-11!GO:0006261;DNA-dependent DNA replication;4.36308293864235e-11!GO:0008639;small protein conjugating enzyme activity;4.62781737636541e-11!GO:0008026;ATP-dependent helicase activity;5.57142454525912e-11!GO:0043687;post-translational protein modification;7.1400982777988e-11!GO:0016192;vesicle-mediated transport;7.93806880711618e-11!GO:0015630;microtubule cytoskeleton;8.7177802506267e-11!GO:0006732;coenzyme metabolic process;8.92650026585781e-11!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;8.92650026585781e-11!GO:0004812;aminoacyl-tRNA ligase activity;8.92650026585781e-11!GO:0016875;ligase activity, forming carbon-oxygen bonds;8.92650026585781e-11!GO:0016607;nuclear speck;8.95931277225823e-11!GO:0043566;structure-specific DNA binding;9.05764688553188e-11!GO:0004842;ubiquitin-protein ligase activity;1.01013764407487e-10!GO:0019787;small conjugating protein ligase activity;1.02231320123522e-10!GO:0006334;nucleosome assembly;1.48082375107088e-10!GO:0000775;chromosome, pericentric region;1.58144861499154e-10!GO:0005793;ER-Golgi intermediate compartment;2.39147439511397e-10!GO:0043038;amino acid activation;2.4351110383599e-10!GO:0006418;tRNA aminoacylation for protein translation;2.4351110383599e-10!GO:0043039;tRNA aminoacylation;2.4351110383599e-10!GO:0009259;ribonucleotide metabolic process;3.1075473618943e-10!GO:0016879;ligase activity, forming carbon-nitrogen bonds;3.78003485447238e-10!GO:0003697;single-stranded DNA binding;4.21639009859328e-10!GO:0006163;purine nucleotide metabolic process;4.80231025365936e-10!GO:0030532;small nuclear ribonucleoprotein complex;5.19667495597446e-10!GO:0016779;nucleotidyltransferase activity;6.27967297576942e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;6.50115820116332e-10!GO:0009055;electron carrier activity;6.6774095848227e-10!GO:0006461;protein complex assembly;8.30001055160767e-10!GO:0031497;chromatin assembly;1.08367528025333e-09!GO:0005667;transcription factor complex;1.33412306949997e-09!GO:0016881;acid-amino acid ligase activity;1.72762798021391e-09!GO:0006164;purine nucleotide biosynthetic process;2.05034996223129e-09!GO:0051028;mRNA transport;2.36717099910153e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;3.58693851499588e-09!GO:0009150;purine ribonucleotide metabolic process;3.7178216279505e-09!GO:0042175;nuclear envelope-endoplasmic reticulum network;3.89030396139105e-09!GO:0051188;cofactor biosynthetic process;4.82976649491006e-09!GO:0009260;ribonucleotide biosynthetic process;4.83804749157001e-09!GO:0048523;negative regulation of cellular process;5.89435401790947e-09!GO:0005819;spindle;6.29429653177108e-09!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;9.1779882420889e-09!GO:0051246;regulation of protein metabolic process;1.02619424796512e-08!GO:0016568;chromatin modification;1.1980518123358e-08!GO:0009056;catabolic process;1.30161735232733e-08!GO:0005789;endoplasmic reticulum membrane;1.30378992115236e-08!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.43092152394316e-08!GO:0015986;ATP synthesis coupled proton transport;1.46985878458647e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.46985878458647e-08!GO:0009152;purine ribonucleotide biosynthetic process;1.57971826362556e-08!GO:0008565;protein transporter activity;1.65736501297008e-08!GO:0043067;regulation of programmed cell death;2.29078216180318e-08!GO:0042981;regulation of apoptosis;2.80770401377783e-08!GO:0019222;regulation of metabolic process;2.85124452531114e-08!GO:0000245;spliceosome assembly;3.71819185051591e-08!GO:0005657;replication fork;5.66566054847362e-08!GO:0003899;DNA-directed RNA polymerase activity;5.66566054847362e-08!GO:0007051;spindle organization and biogenesis;5.77437758795742e-08!GO:0051170;nuclear import;5.77437758795742e-08!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;6.22137376014332e-08!GO:0006888;ER to Golgi vesicle-mediated transport;6.3021497161529e-08!GO:0005813;centrosome;7.21596379801569e-08!GO:0015078;hydrogen ion transmembrane transporter activity;8.54058533086671e-08!GO:0005839;proteasome core complex (sensu Eukaryota);8.95920760322949e-08!GO:0009199;ribonucleoside triphosphate metabolic process;9.07463248456947e-08!GO:0009141;nucleoside triphosphate metabolic process;1.04694277927193e-07!GO:0019829;cation-transporting ATPase activity;1.37257263116281e-07!GO:0051329;interphase of mitotic cell cycle;1.65290114856655e-07!GO:0046034;ATP metabolic process;1.84285873356865e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.85882581917636e-07!GO:0009144;purine nucleoside triphosphate metabolic process;1.85882581917636e-07!GO:0009142;nucleoside triphosphate biosynthetic process;1.85882581917636e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.85882581917636e-07!GO:0006606;protein import into nucleus;1.97395754115475e-07!GO:0050789;regulation of biological process;1.99204864015336e-07!GO:0005815;microtubule organizing center;2.21856389452696e-07!GO:0043069;negative regulation of programmed cell death;2.38680178482432e-07!GO:0048519;negative regulation of biological process;2.40551634944883e-07!GO:0006754;ATP biosynthetic process;2.65564461932449e-07!GO:0006753;nucleoside phosphate metabolic process;2.65564461932449e-07!GO:0016787;hydrolase activity;2.80159339608112e-07!GO:0000075;cell cycle checkpoint;2.96082551073393e-07!GO:0009108;coenzyme biosynthetic process;2.98832729626997e-07!GO:0031324;negative regulation of cellular metabolic process;3.22333756267933e-07!GO:0007005;mitochondrion organization and biogenesis;3.67898630916864e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;3.8913924530027e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;3.8913924530027e-07!GO:0032446;protein modification by small protein conjugation;4.06086359513294e-07!GO:0009060;aerobic respiration;4.3971160263865e-07!GO:0043623;cellular protein complex assembly;5.0187713082838e-07!GO:0016469;proton-transporting two-sector ATPase complex;5.03637218235295e-07!GO:0043066;negative regulation of apoptosis;5.31111001916581e-07!GO:0045259;proton-transporting ATP synthase complex;6.72026008418326e-07!GO:0051325;interphase;6.72755796988455e-07!GO:0004298;threonine endopeptidase activity;6.93350395820502e-07!GO:0016567;protein ubiquitination;7.52484442865043e-07!GO:0003724;RNA helicase activity;7.6223575348088e-07!GO:0000151;ubiquitin ligase complex;8.44822240506778e-07!GO:0007249;I-kappaB kinase/NF-kappaB cascade;8.52545012518318e-07!GO:0005762;mitochondrial large ribosomal subunit;8.54764229558869e-07!GO:0000315;organellar large ribosomal subunit;8.54764229558869e-07!GO:0005768;endosome;8.85333965758392e-07!GO:0009117;nucleotide metabolic process;9.24332673141431e-07!GO:0006916;anti-apoptosis;9.60752895990924e-07!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;9.92484385049952e-07!GO:0031202;RNA splicing factor activity, transesterification mechanism;9.95545360717212e-07!GO:0016740;transferase activity;1.09541092462206e-06!GO:0016564;transcription repressor activity;1.17852168740088e-06!GO:0030120;vesicle coat;1.19947666426295e-06!GO:0030662;coated vesicle membrane;1.19947666426295e-06!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.52455405342631e-06!GO:0007088;regulation of mitosis;2.28027546613439e-06!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.34513156240836e-06!GO:0045333;cellular respiration;2.38133478205031e-06!GO:0003714;transcription corepressor activity;2.53786042042402e-06!GO:0003924;GTPase activity;3.00047334594641e-06!GO:0006099;tricarboxylic acid cycle;3.82144819898292e-06!GO:0046356;acetyl-CoA catabolic process;3.82144819898292e-06!GO:0008094;DNA-dependent ATPase activity;4.05891832893854e-06!GO:0003690;double-stranded DNA binding;4.6048515216075e-06!GO:0031323;regulation of cellular metabolic process;4.8043791383241e-06!GO:0000314;organellar small ribosomal subunit;5.37896538467831e-06!GO:0005763;mitochondrial small ribosomal subunit;5.37896538467831e-06!GO:0006793;phosphorus metabolic process;5.92080309415017e-06!GO:0006796;phosphate metabolic process;5.92080309415017e-06!GO:0006752;group transfer coenzyme metabolic process;6.15496906347889e-06!GO:0048475;coated membrane;6.73654786703653e-06!GO:0030117;membrane coat;6.73654786703653e-06!GO:0003713;transcription coactivator activity;7.06246737860081e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;9.34632783434158e-06!GO:0006350;transcription;9.40737149231163e-06!GO:0007059;chromosome segregation;9.43274263528579e-06!GO:0016563;transcription activator activity;9.5620965043604e-06!GO:0008033;tRNA processing;9.62670859731773e-06!GO:0006084;acetyl-CoA metabolic process;9.80652033466182e-06!GO:0051427;hormone receptor binding;9.9574956211277e-06!GO:0045786;negative regulation of progression through cell cycle;1.01433670502958e-05!GO:0044452;nucleolar part;1.07086330374916e-05!GO:0051052;regulation of DNA metabolic process;1.09701687809613e-05!GO:0000776;kinetochore;1.11177306118649e-05!GO:0006302;double-strand break repair;1.12787152659076e-05!GO:0000786;nucleosome;1.17039719513982e-05!GO:0044440;endosomal part;1.22939945576775e-05!GO:0010008;endosome membrane;1.22939945576775e-05!GO:0051168;nuclear export;1.2311898743311e-05!GO:0006613;cotranslational protein targeting to membrane;1.31849877746161e-05!GO:0009892;negative regulation of metabolic process;1.41152368090388e-05!GO:0006357;regulation of transcription from RNA polymerase II promoter;1.73367186815856e-05!GO:0003682;chromatin binding;1.88732837866975e-05!GO:0035257;nuclear hormone receptor binding;2.36402266394034e-05!GO:0005788;endoplasmic reticulum lumen;2.50925819978268e-05!GO:0044431;Golgi apparatus part;2.64380110496818e-05!GO:0006310;DNA recombination;3.02792915637745e-05!GO:0007010;cytoskeleton organization and biogenesis;3.37873723348428e-05!GO:0051187;cofactor catabolic process;3.43420245706715e-05!GO:0005769;early endosome;3.59617549800472e-05!GO:0005525;GTP binding;3.70729543079015e-05!GO:0043681;protein import into mitochondrion;4.28299260771483e-05!GO:0009109;coenzyme catabolic process;4.70240316858133e-05!GO:0005770;late endosome;4.72562416106095e-05!GO:0043021;ribonucleoprotein binding;4.80836751318783e-05!GO:0016481;negative regulation of transcription;4.95928571211413e-05!GO:0019899;enzyme binding;5.03382458638491e-05!GO:0008186;RNA-dependent ATPase activity;5.14854792621477e-05!GO:0003684;damaged DNA binding;5.72549767510833e-05!GO:0006414;translational elongation;5.92423292634719e-05!GO:0016310;phosphorylation;6.0361522240143e-05!GO:0030880;RNA polymerase complex;6.21488546118017e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;6.40467311513959e-05!GO:0019867;outer membrane;8.90736277317267e-05!GO:0000059;protein import into nucleus, docking;8.90736277317267e-05!GO:0030867;rough endoplasmic reticulum membrane;9.86626826578717e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;9.87342716616922e-05!GO:0031072;heat shock protein binding;0.000108476992502561!GO:0010468;regulation of gene expression;0.000108557553141393!GO:0005874;microtubule;0.000109176964098271!GO:0031968;organelle outer membrane;0.000112024028336113!GO:0016853;isomerase activity;0.000114877139106318!GO:0016363;nuclear matrix;0.000124708935191341!GO:0004527;exonuclease activity;0.000124708935191341!GO:0005048;signal sequence binding;0.00013237022842846!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000132465316622297!GO:0000082;G1/S transition of mitotic cell cycle;0.000137384656590803!GO:0003729;mRNA binding;0.000143995446811087!GO:0006950;response to stress;0.000147454804045593!GO:0004004;ATP-dependent RNA helicase activity;0.000150212757645778!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000153177673146251!GO:0000428;DNA-directed RNA polymerase complex;0.000153177673146251!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000153554540996565!GO:0007093;mitotic cell cycle checkpoint;0.000157292447190748!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000167606677111181!GO:0016859;cis-trans isomerase activity;0.00017517689257625!GO:0048522;positive regulation of cellular process;0.000214271310778299!GO:0005798;Golgi-associated vesicle;0.000224368424796475!GO:0006612;protein targeting to membrane;0.00023838109852027!GO:0033116;ER-Golgi intermediate compartment membrane;0.000243213280224876!GO:0007052;mitotic spindle organization and biogenesis;0.000249120002174324!GO:0031252;leading edge;0.00026210101163873!GO:0006626;protein targeting to mitochondrion;0.000269282958516603!GO:0007017;microtubule-based process;0.000270752970705241!GO:0008654;phospholipid biosynthetic process;0.000275614535378854!GO:0008250;oligosaccharyl transferase complex;0.000324317073032608!GO:0008168;methyltransferase activity;0.000343221929743423!GO:0003678;DNA helicase activity;0.000347867393104805!GO:0043596;nuclear replication fork;0.000353811676052461!GO:0032508;DNA duplex unwinding;0.000354919980718624!GO:0032392;DNA geometric change;0.000354919980718624!GO:0000139;Golgi membrane;0.000357888770230825!GO:0016741;transferase activity, transferring one-carbon groups;0.000361579852837609!GO:0006383;transcription from RNA polymerase III promoter;0.000364353676221844!GO:0045454;cell redox homeostasis;0.000378785942466867!GO:0006275;regulation of DNA replication;0.00038974171288551!GO:0032561;guanyl ribonucleotide binding;0.00039207484937192!GO:0019001;guanyl nucleotide binding;0.00039207484937192!GO:0005741;mitochondrial outer membrane;0.000416747860301049!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00043410845041035!GO:0004576;oligosaccharyl transferase activity;0.000450763385634482!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000453255614498777!GO:0006352;transcription initiation;0.000587752351876359!GO:0007006;mitochondrial membrane organization and biogenesis;0.000608798266651004!GO:0000049;tRNA binding;0.000673557551992202!GO:0046483;heterocycle metabolic process;0.000696757465727495!GO:0005684;U2-dependent spliceosome;0.000696757465727495!GO:0032774;RNA biosynthetic process;0.000715992645312163!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00072500362809733!GO:0004518;nuclease activity;0.000741582683998159!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000745004699276826!GO:0016044;membrane organization and biogenesis;0.000763332700574752!GO:0065007;biological regulation;0.000770421731379538!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000770421731379538!GO:0003677;DNA binding;0.000770421731379538!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000781795127080146!GO:0005885;Arp2/3 protein complex;0.000781795127080146!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.000817158129117957!GO:0006268;DNA unwinding during replication;0.000877876706825522!GO:0008139;nuclear localization sequence binding;0.00089390877154949!GO:0005876;spindle microtubule;0.000914549939686753!GO:0051789;response to protein stimulus;0.000936183711218907!GO:0006986;response to unfolded protein;0.000936183711218907!GO:0009112;nucleobase metabolic process;0.000942975518739052!GO:0006351;transcription, DNA-dependent;0.000980083800935648!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00102914329027418!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00102914329027418!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00102914329027418!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00106238846905033!GO:0030036;actin cytoskeleton organization and biogenesis;0.00106238846905033!GO:0009165;nucleotide biosynthetic process;0.00107126269370817!GO:0018196;peptidyl-asparagine modification;0.00110794538325897!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00110794538325897!GO:0048471;perinuclear region of cytoplasm;0.00113847767674403!GO:0006402;mRNA catabolic process;0.00118251361975479!GO:0006284;base-excision repair;0.00118635514631719!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00127985281483829!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00127985281483829!GO:0051252;regulation of RNA metabolic process;0.00128831752277779!GO:0015631;tubulin binding;0.00134069303429966!GO:0019843;rRNA binding;0.00140782898692581!GO:0016272;prefoldin complex;0.00140782898692581!GO:0031988;membrane-bound vesicle;0.00141880239785715!GO:0007243;protein kinase cascade;0.00149451459344137!GO:0009116;nucleoside metabolic process;0.00155812420388684!GO:0043601;nuclear replisome;0.00159919693413965!GO:0030894;replisome;0.00159919693413965!GO:0000228;nuclear chromosome;0.00159919693413965!GO:0006401;RNA catabolic process;0.00161642775304761!GO:0042802;identical protein binding;0.00169110042940854!GO:0006839;mitochondrial transport;0.00169771474867168!GO:0051540;metal cluster binding;0.00176304789409079!GO:0051536;iron-sulfur cluster binding;0.00176304789409079!GO:0048500;signal recognition particle;0.00181144582134501!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.00188946909844873!GO:0016491;oxidoreductase activity;0.00204111642767981!GO:0051087;chaperone binding;0.0020903419396842!GO:0051920;peroxiredoxin activity;0.00209042043672571!GO:0046474;glycerophospholipid biosynthetic process;0.00209449657667452!GO:0030132;clathrin coat of coated pit;0.00209502812000313!GO:0016023;cytoplasmic membrane-bound vesicle;0.00209936264359736!GO:0051539;4 iron, 4 sulfur cluster binding;0.00211829991831149!GO:0003746;translation elongation factor activity;0.00213533616134841!GO:0000922;spindle pole;0.0023094181390289!GO:0006405;RNA export from nucleus;0.00235429085513451!GO:0006270;DNA replication initiation;0.00248126714504886!GO:0005637;nuclear inner membrane;0.00252544017919292!GO:0008022;protein C-terminus binding;0.00293934481327827!GO:0005773;vacuole;0.00307805646101285!GO:0006611;protein export from nucleus;0.00328963873032569!GO:0043284;biopolymer biosynthetic process;0.00342134413678978!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00349364424806806!GO:0015002;heme-copper terminal oxidase activity;0.00349364424806806!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00349364424806806!GO:0004129;cytochrome-c oxidase activity;0.00349364424806806!GO:0000819;sister chromatid segregation;0.00349364424806806!GO:0006417;regulation of translation;0.00355717900534861!GO:0006091;generation of precursor metabolites and energy;0.00355717900534861!GO:0008312;7S RNA binding;0.00359406321178747!GO:0045449;regulation of transcription;0.00365091963459291!GO:0046489;phosphoinositide biosynthetic process;0.0036649252515695!GO:0005905;coated pit;0.00373069739834526!GO:0008408;3'-5' exonuclease activity;0.00383298196579064!GO:0006818;hydrogen transport;0.00386838114732814!GO:0008180;signalosome;0.00388397470651563!GO:0043022;ribosome binding;0.00393453316664444!GO:0000792;heterochromatin;0.00395720116157798!GO:0032200;telomere organization and biogenesis;0.00397300168517859!GO:0000723;telomere maintenance;0.00397300168517859!GO:0015992;proton transport;0.00401983262249701!GO:0005791;rough endoplasmic reticulum;0.00412463275285407!GO:0003711;transcription elongation regulator activity;0.00412463275285407!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00413910521693538!GO:0000070;mitotic sister chromatid segregation;0.00419854325198318!GO:0006595;polyamine metabolic process;0.0042110417472034!GO:0007050;cell cycle arrest;0.00422475076118652!GO:0008361;regulation of cell size;0.00458868372141276!GO:0008632;apoptotic program;0.00459265672455638!GO:0048146;positive regulation of fibroblast proliferation;0.00469082750593643!GO:0048487;beta-tubulin binding;0.00469097998228538!GO:0048144;fibroblast proliferation;0.00469383299833406!GO:0048145;regulation of fibroblast proliferation;0.00469383299833406!GO:0000725;recombinational repair;0.00481717379726054!GO:0000724;double-strand break repair via homologous recombination;0.00481717379726054!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00497958462443978!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00499290383875936!GO:0045047;protein targeting to ER;0.00499290383875936!GO:0044454;nuclear chromosome part;0.00500290562413683!GO:0031982;vesicle;0.00503434457028048!GO:0016251;general RNA polymerase II transcription factor activity;0.00520033842643247!GO:0030029;actin filament-based process;0.00542373760619628!GO:0000781;chromosome, telomeric region;0.00550347691253598!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.00555125058624264!GO:0035258;steroid hormone receptor binding;0.00557672841299218!GO:0004674;protein serine/threonine kinase activity;0.00593602561619015!GO:0006289;nucleotide-excision repair;0.00599988277372189!GO:0006520;amino acid metabolic process;0.00601360669623913!GO:0046966;thyroid hormone receptor binding;0.00601417222600442!GO:0031970;organelle envelope lumen;0.00607676947228276!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0062094405053355!GO:0030176;integral to endoplasmic reticulum membrane;0.00625339689545569!GO:0004532;exoribonuclease activity;0.00637427897268321!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00637427897268321!GO:0000339;RNA cap binding;0.00638851722616273!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00695611823029551!GO:0004003;ATP-dependent DNA helicase activity;0.00702057759897007!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.00713801356905162!GO:0015399;primary active transmembrane transporter activity;0.00713801356905162!GO:0030134;ER to Golgi transport vesicle;0.00720521799226565!GO:0006891;intra-Golgi vesicle-mediated transport;0.00723638185542188!GO:0001726;ruffle;0.00725303018243848!GO:0031570;DNA integrity checkpoint;0.00729302494569965!GO:0030658;transport vesicle membrane;0.00741705812577505!GO:0005669;transcription factor TFIID complex;0.00768431743678022!GO:0001558;regulation of cell growth;0.00770268134823951!GO:0065009;regulation of a molecular function;0.00775757995541509!GO:0016584;nucleosome positioning;0.00787581570665482!GO:0031901;early endosome membrane;0.0079568199841413!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0079568199841413!GO:0006376;mRNA splice site selection;0.00798252563325001!GO:0000389;nuclear mRNA 3'-splice site recognition;0.00798252563325001!GO:0031124;mRNA 3'-end processing;0.00808750132757206!GO:0016049;cell growth;0.00815941355946905!GO:0005758;mitochondrial intermembrane space;0.00815941355946905!GO:0005832;chaperonin-containing T-complex;0.00827453968072161!GO:0000323;lytic vacuole;0.00828232055945249!GO:0005764;lysosome;0.00828232055945249!GO:0015980;energy derivation by oxidation of organic compounds;0.00834415871570342!GO:0030663;COPI coated vesicle membrane;0.00843757993835184!GO:0030126;COPI vesicle coat;0.00843757993835184!GO:0046822;regulation of nucleocytoplasmic transport;0.00845235919010525!GO:0031902;late endosome membrane;0.00878282247226752!GO:0031410;cytoplasmic vesicle;0.00888656854204112!GO:0042770;DNA damage response, signal transduction;0.00909594769750244!GO:0032984;macromolecular complex disassembly;0.00909594769750244!GO:0019783;small conjugating protein-specific protease activity;0.00911325800093141!GO:0000152;nuclear ubiquitin ligase complex;0.00924234607789875!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0093248253697387!GO:0043488;regulation of mRNA stability;0.0093681213916904!GO:0043487;regulation of RNA stability;0.0093681213916904!GO:0000178;exosome (RNase complex);0.00943579271828401!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00970958257900433!GO:0031577;spindle checkpoint;0.00979187174177259!GO:0045045;secretory pathway;0.00981937181038316!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.00985454083952596!GO:0030127;COPII vesicle coat;0.00995219627745152!GO:0012507;ER to Golgi transport vesicle membrane;0.00995219627745152!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00995219627745152!GO:0042393;histone binding;0.0102499344932982!GO:0009451;RNA modification;0.0102997564624989!GO:0043241;protein complex disassembly;0.0103175578320436!GO:0008234;cysteine-type peptidase activity;0.0103183816606013!GO:0032259;methylation;0.0103470620744778!GO:0045941;positive regulation of transcription;0.0103955124858065!GO:0006144;purine base metabolic process;0.0105555479478354!GO:0045893;positive regulation of transcription, DNA-dependent;0.0105669435600322!GO:0046467;membrane lipid biosynthetic process;0.0106563947200972!GO:0051059;NF-kappaB binding;0.0108410557461847!GO:0003702;RNA polymerase II transcription factor activity;0.0108575342872546!GO:0043433;negative regulation of transcription factor activity;0.0109353590340887!GO:0004843;ubiquitin-specific protease activity;0.0110474808730227!GO:0006497;protein amino acid lipidation;0.0110587612462295!GO:0005869;dynactin complex;0.0112484550913718!GO:0022415;viral reproductive process;0.0113888693117854!GO:0045892;negative regulation of transcription, DNA-dependent;0.0115097324407996!GO:0030118;clathrin coat;0.0119906658290322!GO:0006378;mRNA polyadenylation;0.0119906658290322!GO:0030137;COPI-coated vesicle;0.0120903933056822!GO:0048468;cell development;0.0121557371729705!GO:0006338;chromatin remodeling;0.0125155007542153!GO:0000096;sulfur amino acid metabolic process;0.0135887833897184!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0137258328750635!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0137258328750635!GO:0030660;Golgi-associated vesicle membrane;0.0139599266345398!GO:0022890;inorganic cation transmembrane transporter activity;0.0142758870971338!GO:0043624;cellular protein complex disassembly;0.014297435893044!GO:0000910;cytokinesis;0.0147536704170416!GO:0051101;regulation of DNA binding;0.0147738797289232!GO:0006984;ER-nuclear signaling pathway;0.0147801722177986!GO:0006892;post-Golgi vesicle-mediated transport;0.0149890278031176!GO:0031326;regulation of cellular biosynthetic process;0.0153988498850581!GO:0031625;ubiquitin protein ligase binding;0.0155515825804387!GO:0031529;ruffle organization and biogenesis;0.0160410734958549!GO:0043414;biopolymer methylation;0.0160582069821716!GO:0009967;positive regulation of signal transduction;0.0162570254236335!GO:0000118;histone deacetylase complex;0.0162995348283188!GO:0005732;small nucleolar ribonucleoprotein complex;0.0164048617395135!GO:0016790;thiolester hydrolase activity;0.0164301203990143!GO:0007004;telomere maintenance via telomerase;0.0166768737931716!GO:0031371;ubiquitin conjugating enzyme complex;0.0166823872001439!GO:0008538;proteasome activator activity;0.016770902335536!GO:0030521;androgen receptor signaling pathway;0.017036986154006!GO:0046112;nucleobase biosynthetic process;0.017211875063253!GO:0006213;pyrimidine nucleoside metabolic process;0.0172906731439218!GO:0006778;porphyrin metabolic process;0.0175021100422172!GO:0033013;tetrapyrrole metabolic process;0.0175021100422172!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0175610048797692!GO:0045039;protein import into mitochondrial inner membrane;0.0175610048797692!GO:0051053;negative regulation of DNA metabolic process;0.018138526306195!GO:0004523;ribonuclease H activity;0.0183199169944022!GO:0022411;cellular component disassembly;0.0183813316249685!GO:0030133;transport vesicle;0.0183813316249685!GO:0031123;RNA 3'-end processing;0.01840634610768!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0185400676549596!GO:0048518;positive regulation of biological process;0.0185522461162972!GO:0007346;regulation of progression through mitotic cell cycle;0.0185891687576221!GO:0051348;negative regulation of transferase activity;0.0192939169384764!GO:0051098;regulation of binding;0.0200265307052148!GO:0033673;negative regulation of kinase activity;0.020163406161783!GO:0006469;negative regulation of protein kinase activity;0.020163406161783!GO:0004221;ubiquitin thiolesterase activity;0.0203905110824176!GO:0008017;microtubule binding;0.0204260169007021!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0205332073664109!GO:0006506;GPI anchor biosynthetic process;0.0206999917633529!GO:0007021;tubulin folding;0.0214224674706213!GO:0030125;clathrin vesicle coat;0.0214464842246507!GO:0030665;clathrin coated vesicle membrane;0.0214464842246507!GO:0006607;NLS-bearing substrate import into nucleus;0.021456222216556!GO:0043189;H4/H2A histone acetyltransferase complex;0.0216776701753221!GO:0003887;DNA-directed DNA polymerase activity;0.0226025236774109!GO:0009889;regulation of biosynthetic process;0.0228069802755094!GO:0006509;membrane protein ectodomain proteolysis;0.0241999538438489!GO:0033619;membrane protein proteolysis;0.0241999538438489!GO:0008047;enzyme activator activity;0.0242891115689393!GO:0040029;regulation of gene expression, epigenetic;0.0248803722149026!GO:0043065;positive regulation of apoptosis;0.0251034201189575!GO:0006360;transcription from RNA polymerase I promoter;0.0253073333677211!GO:0006400;tRNA modification;0.0255807265024845!GO:0006650;glycerophospholipid metabolic process;0.0259218036927232!GO:0005680;anaphase-promoting complex;0.0259482928723978!GO:0005875;microtubule associated complex;0.0260098546179362!GO:0006505;GPI anchor metabolic process;0.0260928436968037!GO:0006278;RNA-dependent DNA replication;0.0265425061579065!GO:0000077;DNA damage checkpoint;0.0267445630078428!GO:0045792;negative regulation of cell size;0.0267445630078428!GO:0006355;regulation of transcription, DNA-dependent;0.0268023578619204!GO:0043130;ubiquitin binding;0.0268084600513128!GO:0032182;small conjugating protein binding;0.0268084600513128!GO:0016197;endosome transport;0.0269198085838299!GO:0004721;phosphoprotein phosphatase activity;0.0275630954978025!GO:0000175;3'-5'-exoribonuclease activity;0.0277936082682656!GO:0042158;lipoprotein biosynthetic process;0.0278371850138648!GO:0009066;aspartate family amino acid metabolic process;0.0278562959393577!GO:0043068;positive regulation of programmed cell death;0.0279965364294168!GO:0008243;plasminogen activator activity;0.0280305756764792!GO:0030308;negative regulation of cell growth;0.0280364974041512!GO:0005652;nuclear lamina;0.0280703042911486!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0281000262201614!GO:0030911;TPR domain binding;0.0281400330419885!GO:0006779;porphyrin biosynthetic process;0.0282241249031101!GO:0033014;tetrapyrrole biosynthetic process;0.0282241249031101!GO:0043492;ATPase activity, coupled to movement of substances;0.0287247993866702!GO:0005663;DNA replication factor C complex;0.0292340196746439!GO:0007094;mitotic cell cycle spindle assembly checkpoint;0.0296887090432562!GO:0006740;NADPH regeneration;0.0296887090432562!GO:0006098;pentose-phosphate shunt;0.0296887090432562!GO:0030508;thiol-disulfide exchange intermediate activity;0.0298836698984292!GO:0008276;protein methyltransferase activity;0.0301894262940851!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0302940702432848!GO:0009124;nucleoside monophosphate biosynthetic process;0.0304111061890575!GO:0009123;nucleoside monophosphate metabolic process;0.0304111061890575!GO:0005774;vacuolar membrane;0.0304678177919104!GO:0016791;phosphoric monoester hydrolase activity;0.0312811948917697!GO:0006897;endocytosis;0.0313727915648941!GO:0010324;membrane invagination;0.0313727915648941!GO:0030119;AP-type membrane coat adaptor complex;0.031519934644195!GO:0000726;non-recombinational repair;0.0319645945772718!GO:0046982;protein heterodimerization activity;0.0321579011391075!GO:0008536;Ran GTPase binding;0.0322851289486094!GO:0009303;rRNA transcription;0.032294605392521!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.0326748431621858!GO:0046519;sphingoid metabolic process;0.0328597673246738!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.033142936723816!GO:0005851;eukaryotic translation initiation factor 2B complex;0.0337428915562429!GO:0030032;lamellipodium biogenesis;0.0337428915562429!GO:0046983;protein dimerization activity;0.0338164120121891!GO:0042168;heme metabolic process;0.0339108086267549!GO:0050662;coenzyme binding;0.0341367702462009!GO:0030865;cortical cytoskeleton organization and biogenesis;0.0346005189582091!GO:0005784;translocon complex;0.0346566116661169!GO:0017134;fibroblast growth factor binding;0.0346566116661169!GO:0030041;actin filament polymerization;0.0347781152656021!GO:0035267;NuA4 histone acetyltransferase complex;0.0354827526075653!GO:0019206;nucleoside kinase activity;0.0354987720222291!GO:0016311;dephosphorylation;0.035711486261199!GO:0006007;glucose catabolic process;0.0358479025671603!GO:0050178;phenylpyruvate tautomerase activity;0.0361748815811377!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.0366119005136544!GO:0008637;apoptotic mitochondrial changes;0.0381012972157831!GO:0051338;regulation of transferase activity;0.0384367750784177!GO:0030833;regulation of actin filament polymerization;0.0386611361404571!GO:0006301;postreplication repair;0.0390052224905743!GO:0030384;phosphoinositide metabolic process;0.0391473373203309!GO:0006672;ceramide metabolic process;0.0393162448414694!GO:0000123;histone acetyltransferase complex;0.0393487412204343!GO:0051297;centrosome organization and biogenesis;0.0394444635554751!GO:0031023;microtubule organizing center organization and biogenesis;0.0394444635554751!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0396505508839911!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0406195867951755!GO:0010257;NADH dehydrogenase complex assembly;0.0406195867951755!GO:0033108;mitochondrial respiratory chain complex assembly;0.0406195867951755!GO:0004860;protein kinase inhibitor activity;0.041270851118003!GO:0050681;androgen receptor binding;0.0413417135221682!GO:0030659;cytoplasmic vesicle membrane;0.0415870791531937!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.042031033498512!GO:0030027;lamellipodium;0.0438097515890249!GO:0044450;microtubule organizing center part;0.0438323168708851!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0440159948292684!GO:0022408;negative regulation of cell-cell adhesion;0.0441116157194973!GO:0008156;negative regulation of DNA replication;0.0445920197506827!GO:0008629;induction of apoptosis by intracellular signals;0.0451721122716008!GO:0000209;protein polyubiquitination;0.0460711150634806!GO:0007162;negative regulation of cell adhesion;0.0464976934721965!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0473388632918021!GO:0009119;ribonucleoside metabolic process;0.0477277299804795!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.0478441727588573!GO:0000790;nuclear chromatin;0.0478662901553617!GO:0004177;aminopeptidase activity;0.0486154337278717!GO:0042026;protein refolding;0.0488054733727811!GO:0003725;double-stranded RNA binding;0.0490868261235512!GO:0006730;one-carbon compound metabolic process;0.0493623785577989!GO:0006541;glutamine metabolic process;0.0496505807532426!GO:0003923;GPI-anchor transamidase activity;0.0496505807532426!GO:0016255;attachment of GPI anchor to protein;0.0496505807532426!GO:0042765;GPI-anchor transamidase complex;0.0496505807532426!GO:0006596;polyamine biosynthetic process;0.0498055205644267!GO:0005092;GDP-dissociation inhibitor activity;0.0498471091046593 | |||
|sample_id=10711 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=lung | |||
|top_motifs=ELK1,4_GABP{A,B1}:1.84929527854;GFI1:1.62632958406;CDC5L:1.394150428;TFDP1:1.35914835029;EN1,2:1.3470704703;E2F1..5:1.26451455119;ZBTB16:1.13447226852;POU2F1..3:1.09847186706;ZNF143:1.04130780847;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.03565854695;NFY{A,B,C}:0.956241101566;PITX1..3:0.944205109591;FOXQ1:0.861965253922;FOXD3:0.855981710568;ONECUT1,2:0.84698713163;NKX6-1,2:0.811866286981;PAX3,7:0.801987186499;YY1:0.777887168795;FOX{I1,J2}:0.734407955862;MYB:0.704530156897;ELF1,2,4:0.686105651119;PAX4:0.642027297322;bHLH_family:0.624189754708;HES1:0.598715413486;ALX4:0.592883970472;HOX{A4,D4}:0.585892257539;PAX8:0.569671942623;ALX1:0.565701168717;POU1F1:0.564507764878;BACH2:0.510777875537;NKX3-1:0.480659136914;CDX1,2,4:0.472856006474;HOX{A5,B5}:0.402847894267;NKX2-1,4:0.397378667467;PPARG:0.3704241743;PBX1:0.362525448855;ADNP_IRX_SIX_ZHX:0.358880916696;PRRX1,2:0.337578324585;FOXP1:0.322762385585;GZF1:0.319978166084;HBP1_HMGB_SSRP1_UBTF:0.319304129987;VSX1,2:0.314797596008;NKX2-2,8:0.297892498928;HSF1,2:0.276407171959;BREu{core}:0.253510943829;PAX1,9:0.249437881267;NRF1:0.241269395067;FOS_FOS{B,L1}_JUN{B,D}:0.241249293077;CUX2:0.220427052469;GTF2A1,2:0.209008140846;NFE2L2:0.204829043463;AHR_ARNT_ARNT2:0.19961772788;EVI1:0.188773825075;NFE2:0.180491866362;IKZF2:0.17439155363;MYOD1:0.155719002918;NFIX:0.148264900852;FOXL1:0.145974720071;RXR{A,B,G}:0.1344755544;FOSL2:0.130752167066;KLF4:0.127967285328;TLX1..3_NFIC{dimer}:0.118929055953;FOXM1:0.115667708115;NKX2-3_NKX2-5:0.0774157631055;NFKB1_REL_RELA:0.0772801677308;TOPORS:0.0482625867782;POU3F1..4:0.0338224990193;DMAP1_NCOR{1,2}_SMARC:0.0210962884392;ZIC1..3:0.00814124927486;MYBL2:-0.0102664506826;NR6A1:-0.0254658842298;SOX{8,9,10}:-0.0305036108882;UFEwm:-0.0319148196764;SOX17:-0.0407512020173;TBP:-0.0436955331167;HIC1:-0.0603745627998;OCT4_SOX2{dimer}:-0.068121551749;MZF1:-0.0744804802947;STAT1,3:-0.0968029699843;ARID5B:-0.111003474784;POU5F1:-0.118703412875;ATF5_CREB3:-0.123846617824;HLF:-0.127411895225;ZNF384:-0.128094686764;SPI1:-0.13148179818;PRDM1:-0.135713593463;ZNF423:-0.135715652525;MED-1{core}:-0.144388182629;RFX1:-0.15222309782;SPIB:-0.162499294413;RUNX1..3:-0.16649116786;PAX2:-0.173191021436;ETS1,2:-0.174949365314;TEAD1:-0.175210711848;CRX:-0.195424220134;HOXA9_MEIS1:-0.198656903452;AIRE:-0.205732257336;IRF1,2:-0.218069875237;NR3C1:-0.226357765995;GATA4:-0.227879793724;HNF1A:-0.24202989705;RBPJ:-0.246808017365;ZFP161:-0.259640900991;TEF:-0.260811501459;PAX5:-0.261466187062;XCPE1{core}:-0.274472426293;POU6F1:-0.282050785283;NR5A1,2:-0.282965619693;CEBPA,B_DDIT3:-0.297902015471;HNF4A_NR2F1,2:-0.305850928895;DBP:-0.311532057593;CREB1:-0.340227047117;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.352046532116;MEF2{A,B,C,D}:-0.366919671442;PAX6:-0.370605010123;STAT2,4,6:-0.375130469433;HAND1,2:-0.392666291399;NR1H4:-0.401839910723;IKZF1:-0.410941958835;TFAP2{A,C}:-0.413977206972;FOXP3:-0.414110425816;HOX{A6,A7,B6,B7}:-0.430721903589;GATA6:-0.432364975554;TFAP2B:-0.4349914494;MTE{core}:-0.457800363759;ZBTB6:-0.464683161544;HIF1A:-0.469624348695;BPTF:-0.48113975004;IRF7:-0.481154857156;MTF1:-0.482869713147;HMGA1,2:-0.486339453682;REST:-0.494362349979;GTF2I:-0.495876355896;NKX3-2:-0.496989415162;T:-0.5089770179;JUN:-0.521277800152;LEF1_TCF7_TCF7L1,2:-0.541106849801;ATF4:-0.561124885194;XBP1:-0.562896693039;GFI1B:-0.567073801512;FOXN1:-0.568187052463;SOX5:-0.570585636346;TP53:-0.573212238128;TAL1_TCF{3,4,12}:-0.573684381352;NANOG:-0.591813227078;STAT5{A,B}:-0.592403208426;PATZ1:-0.601447279192;ZEB1:-0.626372286514;ZNF238:-0.628457444353;NHLH1,2:-0.629694160347;SREBF1,2:-0.633072474677;RFX2..5_RFXANK_RFXAP:-0.652215643976;SOX2:-0.659632378797;TLX2:-0.664674756116;RORA:-0.665148803697;TBX4,5:-0.668884017774;SNAI1..3:-0.669679611567;EGR1..3:-0.669690221419;NFIL3:-0.670424547628;FOXA2:-0.672287707766;NANOG{mouse}:-0.679274985318;ZNF148:-0.681465532323;ATF2:-0.687786422624;LHX3,4:-0.690933577036;NFATC1..3:-0.707628885031;AR:-0.71350246006;FOX{D1,D2}:-0.714375218469;NFE2L1:-0.727744457965;TFCP2:-0.781197779028;TFAP4:-0.78823797688;GCM1,2:-0.797332157736;RXRA_VDR{dimer}:-0.803484411226;RREB1:-0.827000453898;PDX1:-0.840757288871;MAZ:-0.860545602735;LMO2:-0.864852169327;SRF:-0.868495866922;ESRRA:-0.883298411265;SPZ1:-0.920946111904;SMAD1..7,9:-0.921058252319;MYFfamily:-0.928083532428;EBF1:-0.967918180924;FOXO1,3,4:-1.00232618768;TGIF1:-1.0577634021;ATF6:-1.06264557037;FOX{F1,F2,J1}:-1.07509872269;SP1:-1.09443341354;EP300:-1.26684598626;GLI1..3:-1.53946975074;MAFB:-1.60105587542;ESR1:-1.63341414791;HMX1:-1.76151997828 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10711-109H9;search_select_hide=table117:FF:10711-109H9 | |||
}} | }} |
Latest revision as of 15:01, 3 June 2020
Name: | fibrous histiocytoma cell line:GCT TIB-223 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11842 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11842
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11842
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.211 |
10 | 10 | 0.117 |
100 | 100 | 0.261 |
101 | 101 | 0.429 |
102 | 102 | 0.423 |
103 | 103 | 0.684 |
104 | 104 | 0.995 |
105 | 105 | 0.354 |
106 | 106 | 0.389 |
107 | 107 | 0.785 |
108 | 108 | 0.965 |
109 | 109 | 0.831 |
11 | 11 | 0.675 |
110 | 110 | 0.287 |
111 | 111 | 0.13 |
112 | 112 | 0.215 |
113 | 113 | 0.209 |
114 | 114 | 0.676 |
115 | 115 | 0.397 |
116 | 116 | 0.78 |
117 | 117 | 0.178 |
118 | 118 | 0.786 |
119 | 119 | 0.416 |
12 | 12 | 0.838 |
120 | 120 | 0.399 |
121 | 121 | 0.89 |
122 | 122 | 0.771 |
123 | 123 | 0.931 |
124 | 124 | 0.271 |
125 | 125 | 0.304 |
126 | 126 | 0.738 |
127 | 127 | 0.316 |
128 | 128 | 0.17 |
129 | 129 | 0.991 |
13 | 13 | 0.106 |
130 | 130 | 0.0676 |
131 | 131 | 0.112 |
132 | 132 | 0.15 |
133 | 133 | 0.109 |
134 | 134 | 0.098 |
135 | 135 | 0.086 |
136 | 136 | 0.0745 |
137 | 137 | 0.673 |
138 | 138 | 0.497 |
139 | 139 | 0.036 |
14 | 14 | 0.322 |
140 | 140 | 0.181 |
141 | 141 | 0.974 |
142 | 142 | 0.52 |
143 | 143 | 0.63 |
144 | 144 | 0.788 |
145 | 145 | 0.585 |
146 | 146 | 0.418 |
147 | 147 | 0.684 |
148 | 148 | 0.867 |
149 | 149 | 0.0788 |
15 | 15 | 0.72 |
150 | 150 | 0.219 |
151 | 151 | 0.0938 |
152 | 152 | 0.226 |
153 | 153 | 0.178 |
154 | 154 | 0.718 |
155 | 155 | 0.289 |
156 | 156 | 0.917 |
157 | 157 | 0.269 |
158 | 158 | 0.433 |
159 | 159 | 0.143 |
16 | 16 | 0.357 |
160 | 160 | 0.681 |
161 | 161 | 0.408 |
162 | 162 | 0.589 |
163 | 163 | 0.992 |
164 | 164 | 0.84 |
165 | 165 | 0.614 |
166 | 166 | 0.28 |
167 | 167 | 0.722 |
168 | 168 | 0.723 |
169 | 169 | 0.0716 |
17 | 17 | 0.632 |
18 | 18 | 0.929 |
19 | 19 | 0.198 |
2 | 2 | 0.192 |
20 | 20 | 0.275 |
21 | 21 | 0.235 |
22 | 22 | 0.131 |
23 | 23 | 0.011 |
24 | 24 | 0.404 |
25 | 25 | 0.669 |
26 | 26 | 0.13 |
27 | 27 | 0.191 |
28 | 28 | 0.948 |
29 | 29 | 0.212 |
3 | 3 | 0.56 |
30 | 30 | 0.125 |
31 | 31 | 0.258 |
32 | 32 | 0.00511 |
33 | 33 | 0.508 |
34 | 34 | 0.182 |
35 | 35 | 0.649 |
36 | 36 | 0.205 |
37 | 37 | 0.716 |
38 | 38 | 0.812 |
39 | 39 | 0.32 |
4 | 4 | 0.302 |
40 | 40 | 0.617 |
41 | 41 | 0.264 |
42 | 42 | 0.283 |
43 | 43 | 0.662 |
44 | 44 | 0.918 |
45 | 45 | 0.281 |
46 | 46 | 0.578 |
47 | 47 | 0.372 |
48 | 48 | 0.268 |
49 | 49 | 0.652 |
5 | 5 | 0.129 |
50 | 50 | 0.824 |
51 | 51 | 0.329 |
52 | 52 | 0.0145 |
53 | 53 | 0.609 |
54 | 54 | 0.31 |
55 | 55 | 0.988 |
56 | 56 | 0.917 |
57 | 57 | 0.388 |
58 | 58 | 0.283 |
59 | 59 | 0.104 |
6 | 6 | 0.233 |
60 | 60 | 0.0717 |
61 | 61 | 0.533 |
62 | 62 | 0.289 |
63 | 63 | 0.924 |
64 | 64 | 0.755 |
65 | 65 | 0.205 |
66 | 66 | 9.64945e-6 |
67 | 67 | 0.223 |
68 | 68 | 0.605 |
69 | 69 | 0.138 |
7 | 7 | 0.892 |
70 | 70 | 0.343 |
71 | 71 | 0.675 |
72 | 72 | 0.313 |
73 | 73 | 0.981 |
74 | 74 | 0.31 |
75 | 75 | 0.107 |
76 | 76 | 0.268 |
77 | 77 | 0.507 |
78 | 78 | 0.827 |
79 | 79 | 0.218 |
8 | 8 | 0.419 |
80 | 80 | 0.129 |
81 | 81 | 0.791 |
82 | 82 | 0.0401 |
83 | 83 | 0.0402 |
84 | 84 | 0.813 |
85 | 85 | 0.0385 |
86 | 86 | 0.732 |
87 | 87 | 0.122 |
88 | 88 | 0.711 |
89 | 89 | 0.272 |
9 | 9 | 0.371 |
90 | 90 | 0.466 |
91 | 91 | 0.0225 |
92 | 92 | 0.162 |
93 | 93 | 0.816 |
94 | 94 | 0.726 |
95 | 95 | 0.423 |
96 | 96 | 0.602 |
97 | 97 | 0.616 |
98 | 98 | 0.673 |
99 | 99 | 0.621 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11842
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0103766 giant cell tumor cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0000151 (secretory cell)
0002320 (connective tissue cell)
0002371 (somatic cell)
0000766 (myeloid leukocyte)
0000219 (motile cell)
0000054 (bone matrix secreting cell)
0000738 (leukocyte)
0000255 (eukaryotic cell)
0002092 (bone marrow cell)
0000137 (osteocyte)
0000092 (osteoclast)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
0060072 (benign neoplasm)
0060085 (organ system benign neoplasm)
7 (disease of anatomical entity)
201 (connective tissue cancer)
0060100 (musculoskeletal system cancer)
3165 (skin benign neoplasm)
0060121 (integumentary system benign neoplasm)
200 (giant cell tumor)
2438 (dermis tumor)
4305 (bone giant cell tumor)
4418 (cutaneous fibrous histiocytoma)
UBERON: Anatomy
0000468 (multi-cellular organism)
0000014 (zone of skin)
0002097 (skin of body)
0002199 (integument)
0002371 (bone marrow)
0001474 (bone element)
0002384 (connective tissue)
0000479 (tissue)
0000064 (organ part)
0000062 (organ)
0004120 (mesoderm-derived structure)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0003102 (surface structure)
0004765 (skeletal element)
0010317 (germ layer / neural crest derived structure)
0002204 (musculoskeletal system)
0001434 (skeletal system)
0002390 (hematopoietic system)
0002193 (hemolymphoid system)
0002405 (immune system)
0002416 (integumental system)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100583 (bone marrow cancer cell sample)
0100372 (bone cancer cell)
0100969 (osteoclastoma cell sample)
0103765 (dermatofibroma cell line)
0103766 (giant cell tumor cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)
CL:0000335 (mesenchyme condensation cell)
UBERON:0002532 (epiblast (generic))
UBERON:0006603 (presumptive mesoderm)
UBERON:0010316 (germ layer / neural crest)