UBERON:0002950: Difference between revisions
From FANTOM5_SSTAR
(Created page with "{{UBERON
|id=UBERON:0002950
|name=regional part of midbrain
|namespace=
|def="A regional part of brain that is part of a midbrain [Obol]." [OBOL:automatic]
|xref=FMA:6199...") |
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{{UBERON | {{UBERON | ||
| | |alt_id=UBERON:NIF_GrossAnatomy_birnlex_763-FMA_61997 | ||
| | |anatomical_img_id=FMA:61997 | ||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
| | |def="A regional part of brain that is part of a midbrain [Obol]." [OBOL:automatic] | ||
|derives_from= | |derives_from= | ||
|develops_from= | |develops_from= | ||
|disjoint_from= | |||
|has_quality= | |has_quality= | ||
|id=UBERON:0002950 | |||
|is_a=UBERON:0002616 | |||
|is_obsolete= | |||
|located_in= | |located_in= | ||
|name=regional part of midbrain | |||
|namespace=FANTOM | |||
|obo_creation_date= | |||
|part_of=UBERON:0001891 | |part_of=UBERON:0001891 | ||
|preceded_by= | |||
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl | |property_value=IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl | ||
|subset= | |||
|synonym="anatomical structure of brain of midbrain" EXACT [OBOL:automatic];;"biological structure of brain of midbrain" EXACT [OBOL:automatic];;"brain anatomical structure of midbrain" EXACT [OBOL:automatic];;"brain biological structure of midbrain" EXACT [OBOL:automatic];;"midbrain anatomical structure of brain" EXACT [OBOL:automatic];;"midbrain biological structure of brain" EXACT [OBOL:automatic];;"midbrain brain anatomical structure" EXACT [OBOL:automatic];;"midbrain brain biological structure" EXACT [OBOL:automatic];;"midbrain neuraxis segment" EXACT [OBOL:automatic];;"midbrain regional part of brain" EXACT [OBOL:automatic];;"midbrain segment" EXACT [FMA:61997];;"midbrain segment of brain" EXACT [OBOL:automatic];;"neuraxis segment of midbrain" EXACT [OBOL:automatic];;"regional part of brain of midbrain" EXACT [OBOL:automatic];;"segment of brain of midbrain" EXACT [OBOL:automatic];;"segment of midbrain" EXACT [NIF_GrossAnatomy:birnlex_763] | |||
|union_of= | |||
|xref=FMA:61997;;NIF_GrossAnatomy:birnlex_763 | |||
}} | }} |
Latest revision as of 17:35, 12 September 2014
Name: | regional part of midbrain | ||
---|---|---|---|
Namespace: | FANTOM | ||
Definition: | "A regional part of brain that is part of a midbrain [Obol]." [OBOL:automatic] | ||
Xrefs: |
| ||
Synonyms: |
"anatomical structure of brain of midbrain" EXACT [OBOL:automatic] "biological structure of brain of midbrain" EXACT [OBOL:automatic] "brain anatomical structure of midbrain" EXACT [OBOL:automatic] "brain biological structure of midbrain" EXACT [OBOL:automatic] "midbrain anatomical structure of brain" EXACT [OBOL:automatic] "midbrain biological structure of brain" EXACT [OBOL:automatic] "midbrain brain anatomical structure" EXACT [OBOL:automatic] "midbrain brain biological structure" EXACT [OBOL:automatic] "midbrain neuraxis segment" EXACT [OBOL:automatic] "midbrain regional part of brain" EXACT [OBOL:automatic] "midbrain segment" EXACT [FMA:61997] "midbrain segment of brain" EXACT [OBOL:automatic] "neuraxis segment of midbrain" EXACT [OBOL:automatic] "regional part of brain of midbrain" EXACT [OBOL:automatic] "segment of brain of midbrain" EXACT [OBOL:automatic] "segment of midbrain" EXACT [NIF_GrossAnatomy:birnlex_763] | ||
Alt_id: | UBERON:NIF_GrossAnatomy_birnlex_763-FMA_61997 |
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
is_a: | UBERON:0002616(regional part of brain) |
---|---|
part_of: | UBERON:0001891(midbrain) |
Children
is a: | UBERON:0002314 (midbrain tectum) |
---|
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 10158-103A5 (substantia nigra, adult, donor10252)
- 10178-103C7 (substantia nigra - adult, donor10196)
- 10358-105E7 (substantia nigra, newborn, donor10223)
- 10371-105G2 (substantia nigra, adult, donor10258)
- 11489-119E4 (Mouse Neurons - substantia nigra, donor4)
- 11490-119E5 (Mouse Neurons - substantia nigra, donor5)
- 11770-123I6 (Mouse Neurons - substantia nigra, donor6)
- 16-22A4 (corpora quadrigemina, adult)
Mouse (Mus musculus)
- 10158-103A5 (substantia nigra, adult, donor10252)
- 10178-103C7 (substantia nigra - adult, donor10196)
- 10358-105E7 (substantia nigra, newborn, donor10223)
- 10371-105G2 (substantia nigra, adult, donor10258)
- 11489-119E4 (Mouse Neurons - substantia nigra, donor4)
- 11490-119E5 (Mouse Neurons - substantia nigra, donor5)
- 11770-123I6 (Mouse Neurons - substantia nigra, donor6)
- 16-22A4 (corpora quadrigemina, adult)
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002950 (regional part of midbrain), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
P-value | FFCP | Short description |
---|---|---|
9.37e-99 | FFCP PHASE2:Hg19::chr9:139916913..139916917,+#_13c30aef985bf4955f282afd3b276ebc | p@chr9:139916913..139916917, + |
9.37e-99 | FFCP PHASE1:Hg19::chr9:139916913..139916917,+#_13c30aef985bf4955f282afd3b276ebc | p@chr9:139916913..139916917, + |
9.37e-99 | FFCP PHASE2:Hg19::chr4:56229918..56229919,-#_13c30aef985bf4955f282afd3b276ebc | p@chr4:56229918..56229919, - |
9.37e-99 | FFCP PHASE2:Hg19::chr10:68718064..68718067,-#_13c30aef985bf4955f282afd3b276ebc | p@chr10:68718064..68718067, - |
9.37e-99 | FFCP PHASE1:Hg19::chr4:56229918..56229919,-#_13c30aef985bf4955f282afd3b276ebc | p@chr4:56229918..56229919, - |
9.37e-99 | FFCP PHASE1:Hg19::chr10:62149979..62149980,-#_13c30aef985bf4955f282afd3b276ebc | p59@ANK3 |
9.37e-99 | FFCP PHASE2:Hg19::chr1:24915966..24915971,+#_13c30aef985bf4955f282afd3b276ebc | p5@C1orf130 |
9.37e-99 | FFCP PHASE1:Hg19::chr10:68718064..68718067,-#_13c30aef985bf4955f282afd3b276ebc | p@chr10:68718064..68718067, - |
9.37e-99 | FFCP PHASE1:Hg19::chr1:24915966..24915971,+#_13c30aef985bf4955f282afd3b276ebc | p5@C1orf130 |
9.37e-99 | FFCP PHASE2:Hg19::chr10:62149979..62149980,-#_13c30aef985bf4955f282afd3b276ebc | p59@ANK3 |
2.55e-98 | FFCP PHASE2:Hg19::chr18:74702556..74702558,-#_e507a854b733ac7500ee560022241c1b | p@chr18:74702556..74702558, - |
2.55e-98 | FFCP PHASE2:Hg19::chr5:57935348..57935354,-#_e507a854b733ac7500ee560022241c1b | p@chr5:57935348..57935354, - |
2.55e-98 | FFCP PHASE2:Hg19::chr1:65776926..65776928,+#_e507a854b733ac7500ee560022241c1b | p@chr1:65776926..65776928, + |
2.55e-98 | FFCP PHASE1:Hg19::chr5:57935348..57935354,-#_e507a854b733ac7500ee560022241c1b | p@chr5:57935348..57935354, - |
2.55e-98 | FFCP PHASE1:Hg19::chr18:74702556..74702558,-#_e507a854b733ac7500ee560022241c1b | p@chr18:74702556..74702558, - |
2.55e-98 | FFCP PHASE1:Hg19::chr1:65776926..65776928,+#_e507a854b733ac7500ee560022241c1b | p@chr1:65776926..65776928, + |
1.23e-66 | FFCP PHASE1:Hg19::chr8:53312058..53312067,-#_2afbe33b3ff608518733346f7e1625f9 | p@chr8:53312058..53312067, - |
1.23e-66 | FFCP PHASE2:Hg19::chr10:22967066..22967069,-#_2afbe33b3ff608518733346f7e1625f9 | p@chr10:22967066..22967069, - |
1.23e-66 | FFCP PHASE1:Hg19::chr16:81170013..81170024,-#_2afbe33b3ff608518733346f7e1625f9 | p6@PKD1L2 |
1.23e-66 | FFCP PHASE2:Hg19::chr16:57309513..57309516,-#_2afbe33b3ff608518733346f7e1625f9 | p@chr16:57309513..57309516, - |
1.23e-66 | FFCP PHASE1:Hg19::chr16:57309513..57309516,-#_2afbe33b3ff608518733346f7e1625f9 | p@chr16:57309513..57309516, - |
1.23e-66 | FFCP PHASE1:Hg19::chr10:22967066..22967069,-#_2afbe33b3ff608518733346f7e1625f9 | p@chr10:22967066..22967069, - |
1.23e-66 | FFCP PHASE2:Hg19::chr16:81170013..81170024,-#_2afbe33b3ff608518733346f7e1625f9 | p6@PKD1L2 |
1.23e-66 | FFCP PHASE2:Hg19::chr8:53312058..53312067,-#_2afbe33b3ff608518733346f7e1625f9 | p@chr8:53312058..53312067, - |
2.39e-66 | FFCP PHASE1:Hg19::chr1:44956567..44956571,+#_c996a56d86627bfda9b6528262ef7624 | p@chr1:44956567..44956571, + |
2.39e-66 | FFCP PHASE1:Hg19::chr11:7340444..7340448,+#_c996a56d86627bfda9b6528262ef7624 | p@chr11:7340444..7340448, + |
2.39e-66 | FFCP PHASE2:Hg19::chr14:95727527..95727529,-#_c996a56d86627bfda9b6528262ef7624 | p@chr14:95727527..95727529, - |
2.39e-66 | FFCP PHASE1:Hg19::chr14:95727527..95727529,-#_c996a56d86627bfda9b6528262ef7624 | p@chr14:95727527..95727529, - |
2.39e-66 | FFCP PHASE2:Hg19::chr1:44956567..44956571,+#_c996a56d86627bfda9b6528262ef7624 | p@chr1:44956567..44956571, + |
2.39e-66 | FFCP PHASE2:Hg19::chr11:7340444..7340448,+#_c996a56d86627bfda9b6528262ef7624 | p@chr11:7340444..7340448, + |
4.66e-66 | FFCP PHASE2:Hg19::chr14:105166013..105166017,+#_fd449d7c45f1b7227f6c9fcce29a31ba | p@chr14:105166013..105166017, + |
4.66e-66 | FFCP PHASE2:Hg19::chr9:79516011..79516022,-#_fd449d7c45f1b7227f6c9fcce29a31ba | p@chr9:79516011..79516022, - |
4.66e-66 | FFCP PHASE2:Hg19::chr17:29623232..29623241,-#_fd449d7c45f1b7227f6c9fcce29a31ba | p8@OMG |
4.66e-66 | FFCP PHASE2:Hg19::chr13:43872447..43872452,-#_fd449d7c45f1b7227f6c9fcce29a31ba | p@chr13:43872447..43872452, - |
4.66e-66 | FFCP PHASE1:Hg19::chr14:105166013..105166017,+#_fd449d7c45f1b7227f6c9fcce29a31ba | p@chr14:105166013..105166017, + |
4.66e-66 | FFCP PHASE1:Hg19::chr9:79516011..79516022,-#_fd449d7c45f1b7227f6c9fcce29a31ba | p@chr9:79516011..79516022, - |
4.66e-66 | FFCP PHASE1:Hg19::chr13:43872447..43872452,-#_fd449d7c45f1b7227f6c9fcce29a31ba | p@chr13:43872447..43872452, - |
4.66e-66 | FFCP PHASE2:Hg19::chr13:34922094..34922105,+#_fd449d7c45f1b7227f6c9fcce29a31ba | p@chr13:34922094..34922105, + |
4.66e-66 | FFCP PHASE1:Hg19::chr17:29623232..29623241,-#_fd449d7c45f1b7227f6c9fcce29a31ba | p8@OMG |
4.66e-66 | FFCP PHASE1:Hg19::chr13:34922094..34922105,+#_fd449d7c45f1b7227f6c9fcce29a31ba | p@chr13:34922094..34922105, + |
1.46e-50 | FFCP PHASE1:Hg19::chrX:28627633..28627642,+#_e5a8ce706b31c1f73ffd2233bd1c205c | p@chrX:28627633..28627642, + |
1.46e-50 | FFCP PHASE2:Hg19::chrX:28627633..28627642,+#_e5a8ce706b31c1f73ffd2233bd1c205c | p@chrX:28627633..28627642, + |
1.46e-50 | FFCP PHASE1:Hg19::chr9:108178201..108178203,+#_e5a8ce706b31c1f73ffd2233bd1c205c | p@chr9:108178201..108178203, + |
1.46e-50 | FFCP PHASE2:Hg19::chr9:108178201..108178203,+#_e5a8ce706b31c1f73ffd2233bd1c205c | p@chr9:108178201..108178203, + |
3.99e-50 | FFCP PHASE1:Hg19::chr20:52570026..52570037,-#_5884383296f1fb2b0a521d6e821ca7bb | p@chr20:52570026..52570037, - |
3.99e-50 | FFCP PHASE2:Hg19::chr3:50717966..50717971,+#_5884383296f1fb2b0a521d6e821ca7bb | p@chr3:50717966..50717971, + |
3.99e-50 | FFCP PHASE1:Hg19::chr3:50717966..50717971,+#_5884383296f1fb2b0a521d6e821ca7bb | p@chr3:50717966..50717971, + |
3.99e-50 | FFCP PHASE2:Hg19::chr6:134626498..134626502,-#_5884383296f1fb2b0a521d6e821ca7bb | p@chr6:134626498..134626502, - |
3.99e-50 | FFCP PHASE1:Hg19::chr6:134626498..134626502,-#_5884383296f1fb2b0a521d6e821ca7bb | p@chr6:134626498..134626502, - |
3.99e-50 | FFCP PHASE2:Hg19::chr6:89803656..89803659,+#_5884383296f1fb2b0a521d6e821ca7bb | p@chr6:89803656..89803659, + |
3.99e-50 | FFCP PHASE2:Hg19::chr20:52570026..52570037,-#_5884383296f1fb2b0a521d6e821ca7bb | p@chr20:52570026..52570037, - |
3.99e-50 | FFCP PHASE1:Hg19::chr6:89803656..89803659,+#_5884383296f1fb2b0a521d6e821ca7bb | p@chr6:89803656..89803659, + |
6.58e-50 | FFCP PHASE2:Hg19::chr9:19515907..19515918,-#_2ef63967c4239e70449c0ae05a8e1749 | p@chr9:19515907..19515918, - |
6.58e-50 | FFCP PHASE1:Hg19::chr6:151042126..151042135,+#_2ef63967c4239e70449c0ae05a8e1749 | p21@PLEKHG1 |
6.58e-50 | FFCP PHASE1:Hg19::chr18:26665245..26665249,+#_2ef63967c4239e70449c0ae05a8e1749 | p@chr18:26665245..26665249, + |
6.58e-50 | FFCP PHASE1:Hg19::chr9:19515907..19515918,-#_2ef63967c4239e70449c0ae05a8e1749 | p@chr9:19515907..19515918, - |
6.58e-50 | FFCP PHASE2:Hg19::chr1:161275096..161275109,-#_2ef63967c4239e70449c0ae05a8e1749 | p@chr1:161275096..161275109, - |
6.58e-50 | FFCP PHASE2:Hg19::chr22:48980473..48980481,+#_2ef63967c4239e70449c0ae05a8e1749 | p@chr22:48980473..48980481, + |
6.58e-50 | FFCP PHASE1:Hg19::chr17:70910145..70910148,-#_2ef63967c4239e70449c0ae05a8e1749 | p@chr17:70910145..70910148, - |
6.58e-50 | FFCP PHASE1:Hg19::chr17:3479944..3479947,-#_2ef63967c4239e70449c0ae05a8e1749 | p@chr17:3479944..3479947, - |
6.58e-50 | FFCP PHASE1:Hg19::chr1:161275096..161275109,-#_2ef63967c4239e70449c0ae05a8e1749 | p@chr1:161275096..161275109, - |
6.58e-50 | FFCP PHASE1:Hg19::chr22:48980473..48980481,+#_2ef63967c4239e70449c0ae05a8e1749 | p@chr22:48980473..48980481, + |
6.58e-50 | FFCP PHASE2:Hg19::chr1:160009700..160009711,-#_2ef63967c4239e70449c0ae05a8e1749 | p10@KCNJ10 |
6.58e-50 | FFCP PHASE2:Hg19::chr6:163745521..163745530,-#_2ef63967c4239e70449c0ae05a8e1749 | p2@LOC285796 |
6.58e-50 | FFCP PHASE1:Hg19::chr9:137240632..137240635,+#_2ef63967c4239e70449c0ae05a8e1749 | p@chr9:137240632..137240635, + |
6.58e-50 | FFCP PHASE2:Hg19::chr9:137240632..137240635,+#_2ef63967c4239e70449c0ae05a8e1749 | p@chr9:137240632..137240635, + |
6.58e-50 | FFCP PHASE2:Hg19::chr18:26665245..26665249,+#_2ef63967c4239e70449c0ae05a8e1749 | p@chr18:26665245..26665249, + |
6.58e-50 | FFCP PHASE2:Hg19::chr6:151042126..151042135,+#_2ef63967c4239e70449c0ae05a8e1749 | p21@PLEKHG1 |
6.58e-50 | FFCP PHASE2:Hg19::chr17:70910145..70910148,-#_2ef63967c4239e70449c0ae05a8e1749 | p@chr17:70910145..70910148, - |
6.58e-50 | FFCP PHASE1:Hg19::chr1:160009700..160009711,-#_2ef63967c4239e70449c0ae05a8e1749 | p10@KCNJ10 |
6.58e-50 | FFCP PHASE1:Hg19::chr6:163745521..163745530,-#_2ef63967c4239e70449c0ae05a8e1749 | p2@LOC285796 |
6.58e-50 | FFCP PHASE2:Hg19::chr17:3479944..3479947,-#_2ef63967c4239e70449c0ae05a8e1749 | p@chr17:3479944..3479947, - |
2.38e-43 | FFCP PHASE2:Mm9::chr19:40804786..40804795,-#_4403ce2cab20455902a71871ad3aabbe | p@chr19:40804786..40804795, - |
2.38e-43 | FFCP PHASE1:Mm9::chr19:40804786..40804795,-#_4403ce2cab20455902a71871ad3aabbe | p@chr19:40804786..40804795, - |
6.62e-41 | FFCP PHASE1:Hg19::chr4:139891920..139891924,-#_d9664c16ef6ac65725191592ce29be43 | p@chr4:139891920..139891924, - |
6.62e-41 | FFCP PHASE2:Hg19::chr5:60933634..60933637,+#_d9664c16ef6ac65725191592ce29be43 | p4@C5orf64 |
6.62e-41 | FFCP PHASE1:Hg19::chr5:60933634..60933637,+#_d9664c16ef6ac65725191592ce29be43 | p4@C5orf64 |
6.62e-41 | FFCP PHASE2:Hg19::chr4:139891920..139891924,-#_d9664c16ef6ac65725191592ce29be43 | p@chr4:139891920..139891924, - |
9.91e-41 | FFCP PHASE1:Hg19::chrX:13792462..13792477,-#_662cc2a2211374e97162d4d078d40b39 | p@chrX:13792462..13792477, - |
9.91e-41 | FFCP PHASE2:Hg19::chrX:13792462..13792477,-#_662cc2a2211374e97162d4d078d40b39 | p@chrX:13792462..13792477, - |
9.91e-41 | FFCP PHASE2:Hg19::chr5:152017019..152017026,+#_662cc2a2211374e97162d4d078d40b39 | p@chr5:152017019..152017026, + |
9.91e-41 | FFCP PHASE2:Hg19::chr13:21100208..21100214,+#_662cc2a2211374e97162d4d078d40b39 | p@chr13:21100208..21100214, + |
9.91e-41 | FFCP PHASE1:Hg19::chr13:21100208..21100214,+#_662cc2a2211374e97162d4d078d40b39 | p@chr13:21100208..21100214, + |
9.91e-41 | FFCP PHASE1:Hg19::chr5:152017019..152017026,+#_662cc2a2211374e97162d4d078d40b39 | p@chr5:152017019..152017026, + |
1.48e-40 | FFCP PHASE1:Hg19::chr17:71046459..71046462,-#_8ecfa3a20ad4f4e7e9f950fa2f6c8e2d | p@chr17:71046459..71046462, - |
1.48e-40 | FFCP PHASE2:Hg19::chr2:135170207..135170218,+#_8ecfa3a20ad4f4e7e9f950fa2f6c8e2d | p@chr2:135170207..135170218, + |
1.48e-40 | FFCP PHASE1:Hg19::chr1:161275238..161275250,-#_8ecfa3a20ad4f4e7e9f950fa2f6c8e2d | p@chr1:161275238..161275250, - |
1.48e-40 | FFCP PHASE2:Hg19::chr1:109806865..109806872,+#_8ecfa3a20ad4f4e7e9f950fa2f6c8e2d | p10@CELSR2 |
1.48e-40 | FFCP PHASE1:Hg19::chr2:135170207..135170218,+#_8ecfa3a20ad4f4e7e9f950fa2f6c8e2d | p@chr2:135170207..135170218, + |
1.48e-40 | FFCP PHASE1:Hg19::chr1:109806865..109806872,+#_8ecfa3a20ad4f4e7e9f950fa2f6c8e2d | p10@CELSR2 |
1.48e-40 | FFCP PHASE2:Hg19::chr17:71046459..71046462,-#_8ecfa3a20ad4f4e7e9f950fa2f6c8e2d | p@chr17:71046459..71046462, - |
1.48e-40 | FFCP PHASE2:Hg19::chr9:139911084..139911102,-#_8ecfa3a20ad4f4e7e9f950fa2f6c8e2d | p@chr9:139911084..139911102, - |
1.48e-40 | FFCP PHASE1:Hg19::chr9:139911084..139911102,-#_8ecfa3a20ad4f4e7e9f950fa2f6c8e2d | p@chr9:139911084..139911102, - |
1.48e-40 | FFCP PHASE2:Hg19::chr1:161275238..161275250,-#_8ecfa3a20ad4f4e7e9f950fa2f6c8e2d | p@chr1:161275238..161275250, - |
2.21e-40 | FFCP PHASE2:Hg19::chr10:1246245..1246252,-#_605c9bbf4e7696c6f9c981d61308471d | p20@ADARB2 |
2.21e-40 | FFCP PHASE2:Hg19::chr8:27522642..27522647,+#_605c9bbf4e7696c6f9c981d61308471d | p@chr8:27522642..27522647, + |
2.21e-40 | FFCP PHASE1:Hg19::chr10:1246202..1246207,-#_605c9bbf4e7696c6f9c981d61308471d | p19@ADARB2 |
2.21e-40 | FFCP PHASE1:Hg19::chrX:103046993..103046994,+#_605c9bbf4e7696c6f9c981d61308471d | p@chrX:103046993..103046994, + |
2.21e-40 | FFCP PHASE2:Hg19::chrX:103046993..103046994,+#_605c9bbf4e7696c6f9c981d61308471d | p@chrX:103046993..103046994, + |
2.21e-40 | FFCP PHASE1:Hg19::chr8:27522642..27522647,+#_605c9bbf4e7696c6f9c981d61308471d | p@chr8:27522642..27522647, + |