Novel motif:111

name:	motif111_WWAATYCGCTCC

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0003230	cardiac atrium development	3.326871e-10
GO:0042088	T-helper 1 type immune response	3.958518e-10
GO:0003209	cardiac atrium morphogenesis	2.604969e-8
GO:0044258	intestinal lipid catabolic process	2.825286e-8
GO:0018350	protein esterification	2.825286e-8
GO:0016056	rhodopsin mediated signaling pathway	4.760697e-8
GO:0060351	cartilage development involved in endochondral bone morphogenesis	5.188048e-8
GO:0060350	endochondral bone morphogenesis	8.278303e-8
GO:0003211	cardiac ventricle formation	9.218040e-8
GO:0006289	nucleotide-excision repair	1.096045e-7
GO:0097022	lymphocyte migration into lymph node	1.995633e-7
GO:0045838	positive regulation of membrane potential	2.094273e-7
GO:0007099	centriole replication	2.790448e-7
GO:0072610	interleukin-12 secretion	3.556003e-7
GO:0002408	myeloid dendritic cell chemotaxis	3.556003e-7
GO:0009404	toxin metabolic process	5.400534e-7
GO:0006283	transcription-coupled nucleotide-excision repair	5.724015e-7
GO:0018126	protein hydroxylation	6.425668e-7
GO:0003283	atrial septum development	1.029772e-6
GO:0032727	positive regulation of interferon-alpha production	1.109333e-6
GO:0032736	positive regulation of interleukin-13 production	1.166774e-6
GO:0034418	urate biosynthetic process	1.223740e-6
GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process	1.260608e-6
GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	1.431194e-6
GO:0010960	magnesium ion homeostasis	2.268049e-6
GO:0046390	ribose phosphate biosynthetic process	3.036533e-6
GO:0006370	mRNA capping	3.810636e-6
GO:2000659	regulation of interleukin-1-mediated signaling pathway	3.909823e-6
GO:2000409	positive regulation of T cell extravasation	4.250381e-6
GO:0043310	negative regulation of eosinophil degranulation	4.250381e-6
GO:0035696	monocyte extravasation	4.250381e-6
GO:0035705	T-helper 17 cell chemotaxis	4.250381e-6
GO:0002831	regulation of response to biotic stimulus	5.432154e-6
GO:0003417	growth plate cartilage development	5.687102e-6
GO:0048630	skeletal muscle tissue growth	5.887350e-6
GO:0007031	peroxisome organization	7.099688e-6
GO:0034695	response to prostaglandin E stimulus	7.667263e-6
GO:0009452	RNA capping	9.153132e-6
GO:0003091	renal water homeostasis	9.377045e-6
GO:0071894	histone H2B conserved C-terminal lysine ubiquitination	1.027610e-5
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	1.034599e-5
GO:0009586	rhodopsin mediated phototransduction	1.043604e-5
GO:0001824	blastocyst development	1.182062e-5
GO:0045175	basal protein localization	1.251930e-5
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	1.381956e-5
GO:0006356	regulation of transcription from RNA polymerase I promoter	1.561214e-5
GO:0044240	multicellular organismal lipid catabolic process	1.620921e-5
GO:0060056	mammary gland involution	1.786715e-5
GO:0051298	centrosome duplication	1.898077e-5
GO:0015887	pantothenate transmembrane transport	2.015123e-5
GO:0015878	biotin transport	2.015123e-5
GO:0002832	negative regulation of response to biotic stimulus	2.078099e-5
GO:0002711	positive regulation of T cell mediated immunity	2.107075e-5
GO:0048627	myoblast development	2.258877e-5
GO:0018364	peptidyl-glutamine methylation	2.293982e-5
GO:0072428	signal transduction involved in intra-S DNA damage checkpoint	2.293982e-5
GO:0003170	heart valve development	2.407136e-5
GO:0032862	activation of Rho GTPase activity	2.494692e-5
GO:2000348	regulation of CD40 signaling pathway	2.807293e-5
GO:0030157	pancreatic juice secretion	3.022343e-5
GO:0060325	face morphogenesis	3.227859e-5
GO:0032753	positive regulation of interleukin-4 production	3.252402e-5
GO:0050935	iridophore differentiation	3.322698e-5
GO:0048937	lateral line nerve glial cell development	3.322698e-5
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	3.395815e-5
GO:0090281	negative regulation of calcium ion import	3.440204e-5
GO:0071584	negative regulation of zinc ion import	3.440204e-5
GO:0071460	cellular response to cell-matrix adhesion	3.596259e-5
GO:0032609	interferon-gamma production	3.606812e-5
GO:0050755	chemokine metabolic process	3.678860e-5
GO:0009440	cyanate catabolic process	3.842175e-5
GO:0007602	phototransduction	4.068084e-5
GO:0042264	peptidyl-aspartic acid hydroxylation	4.621291e-5
GO:0048846	axon extension involved in axon guidance	4.756659e-5
GO:0045980	negative regulation of nucleotide metabolic process	4.803161e-5
GO:0016558	protein import into peroxisome matrix	5.107184e-5
GO:0042696	menarche	5.130286e-5
GO:0032656	regulation of interleukin-13 production	5.566470e-5
GO:0060323	head morphogenesis	5.973540e-5
GO:0070432	regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	6.202814e-5
GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	6.202814e-5
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	6.402074e-5
GO:0030803	negative regulation of cyclic nucleotide biosynthetic process	6.691548e-5
GO:0002697	regulation of immune effector process	6.915114e-5
GO:0048642	negative regulation of skeletal muscle tissue development	7.064149e-5
GO:0006657	CDP-choline pathway	7.423542e-5
GO:0001757	somite specification	8.027866e-5
GO:0001768	establishment of T cell polarity	8.240303e-5
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	8.392676e-5
GO:0046825	regulation of protein export from nucleus	8.515818e-5
GO:0050847	progesterone receptor signaling pathway	9.113582e-5
GO:0021849	neuroblast division in subventricular zone	9.152716e-5
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	9.201100e-5
GO:0051461	positive regulation of corticotropin secretion	9.858182e-5
GO:0032754	positive regulation of interleukin-5 production	9.900373e-5
GO:0007521	muscle cell fate determination	9.915283e-5
GO:0032649	regulation of interferon-gamma production	1.020677e-4
GO:0003179	heart valve morphogenesis	1.036746e-4
GO:0046826	negative regulation of protein export from nucleus	1.067283e-4
GO:0097039	protein linear polyubiquitination	1.067851e-4
GO:0006337	nucleosome disassembly	1.120486e-4
GO:0060980	cell migration involved in coronary vasculogenesis	1.143257e-4
GO:0035910	ascending aorta morphogenesis	1.152900e-4
GO:2000761	positive regulation of N-terminal peptidyl-lysine acetylation	1.152900e-4
GO:0042095	interferon-gamma biosynthetic process	1.166983e-4
GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	1.172872e-4
GO:0044243	multicellular organismal catabolic process	1.248326e-4
GO:0006829	zinc ion transport	1.256515e-4
GO:0042693	muscle cell fate commitment	1.300567e-4
GO:0008628	induction of apoptosis by hormones	1.351304e-4
GO:0003218	cardiac left ventricle formation	1.353375e-4
GO:0045084	positive regulation of interleukin-12 biosynthetic process	1.365026e-4
GO:0060413	atrial septum morphogenesis	1.366325e-4
GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion	1.367605e-4
GO:0030818	negative regulation of cAMP biosynthetic process	1.425848e-4
GO:0015816	glycine transport	1.427291e-4
GO:0043966	histone H3 acetylation	1.486649e-4
GO:0061037	negative regulation of cartilage development	1.489990e-4
GO:0032720	negative regulation of tumor necrosis factor production	1.490431e-4
GO:0042033	chemokine biosynthetic process	1.550763e-4
GO:0042253	granulocyte macrophage colony-stimulating factor biosynthetic process	1.550763e-4
GO:2000256	positive regulation of male germ cell proliferation	1.550763e-4
GO:0042231	interleukin-13 biosynthetic process	1.550763e-4
GO:0010171	body morphogenesis	1.728118e-4
GO:0055078	sodium ion homeostasis	1.729134e-4
GO:0034766	negative regulation of ion transmembrane transport	1.750599e-4
GO:0006625	protein targeting to peroxisome	1.761810e-4
GO:0035909	aorta morphogenesis	1.766956e-4
GO:0050892	intestinal absorption	1.783231e-4
GO:0009953	dorsal/ventral pattern formation	1.792089e-4
GO:0021542	dentate gyrus development	1.854259e-4
GO:0033683	nucleotide-excision repair, DNA incision	1.919567e-4
GO:0002407	dendritic cell chemotaxis	1.952146e-4
GO:0031960	response to corticosteroid stimulus	2.023193e-4
GO:0007589	body fluid secretion	2.035124e-4
GO:0021759	globus pallidus development	2.093929e-4
GO:0006083	acetate metabolic process	2.136583e-4
GO:0030423	targeting of mRNA for destruction involved in RNA interference	2.136583e-4
GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness	2.142027e-4
GO:0001922	B-1 B cell homeostasis	2.143588e-4
GO:0046058	cAMP metabolic process	2.234459e-4
GO:0007603	phototransduction, visible light	2.308069e-4
GO:0014909	smooth muscle cell migration	2.317974e-4
GO:0032615	interleukin-12 production	2.332619e-4
GO:0061043	regulation of vascular wound healing	2.392647e-4
GO:0003416	endochondral bone growth	2.450104e-4
GO:0006982	response to lipid hydroperoxide	2.502418e-4
GO:0009151	purine deoxyribonucleotide metabolic process	2.612745e-4
GO:0050891	multicellular organismal water homeostasis	2.657055e-4
GO:0060349	bone morphogenesis	2.680661e-4
GO:0009448	gamma-aminobutyric acid metabolic process	2.690998e-4
GO:0001825	blastocyst formation	2.731903e-4
GO:0032729	positive regulation of interferon-gamma production	2.855409e-4
GO:0048936	peripheral nervous system neuron axonogenesis	2.928764e-4
GO:0032660	regulation of interleukin-17 production	3.050643e-4
GO:0016191	synaptic vesicle uncoating	3.233265e-4
GO:0050434	positive regulation of viral transcription	3.343317e-4
GO:0002536	respiratory burst involved in inflammatory response	3.413384e-4
GO:0048485	sympathetic nervous system development	3.466748e-4
GO:2000463	positive regulation of excitatory postsynaptic membrane potential	3.534476e-4
GO:0046782	regulation of viral transcription	3.570796e-4
GO:0002839	positive regulation of immune response to tumor cell	3.753898e-4
GO:0060689	cell differentiation involved in salivary gland development	3.890880e-4
GO:0007565	female pregnancy	3.962669e-4
GO:2000756	regulation of peptidyl-lysine acetylation	3.972001e-4
GO:0051384	response to glucocorticoid stimulus	4.024062e-4
GO:0007389	pattern specification process	4.176860e-4
GO:0071374	cellular response to parathyroid hormone stimulus	4.183014e-4
GO:0006844	acyl carnitine transport	4.190339e-4
GO:0006353	transcription termination, DNA-dependent	4.207014e-4
GO:0071481	cellular response to X-ray	4.411401e-4
GO:0035295	tube development	4.542593e-4
GO:0043574	peroxisomal transport	4.827721e-4
GO:0019693	ribose phosphate metabolic process	4.962242e-4
GO:0033159	negative regulation of protein import into nucleus, translocation	5.136440e-4
GO:0021766	hippocampus development	5.202335e-4
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	5.219109e-4
GO:0016246	RNA interference	5.226293e-4
GO:0016082	synaptic vesicle priming	5.255055e-4
GO:0061084	negative regulation of protein refolding	5.483388e-4
GO:0061143	alveolar primary septum development	5.551319e-4
GO:0002699	positive regulation of immune effector process	5.574993e-4
GO:0007522	visceral muscle development	5.654677e-4
GO:2000345	regulation of hepatocyte proliferation	5.786178e-4
GO:0015854	guanine transport	5.941262e-4
GO:0035364	thymine transport	5.941262e-4
GO:0035344	hypoxanthine transport	5.941262e-4
GO:0010836	negative regulation of protein ADP-ribosylation	5.941262e-4
GO:0006424	glutamyl-tRNA aminoacylation	5.941262e-4
GO:0005983	starch catabolic process	5.941262e-4
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	6.034257e-4
GO:0055012	ventricular cardiac muscle cell differentiation	6.037979e-4
GO:0060370	susceptibility to T cell mediated cytotoxicity	6.122353e-4
GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	6.122353e-4
GO:0051083	'de novo' cotranslational protein folding	6.189784e-4
GO:0006333	chromatin assembly or disassembly	6.278003e-4
GO:0060563	neuroepithelial cell differentiation	6.305105e-4
GO:2000009	negative regulation of protein localization at cell surface	6.359049e-4
GO:0090273	regulation of somatostatin secretion	6.426400e-4
GO:0043117	positive regulation of vascular permeability	6.565803e-4
GO:0043382	positive regulation of memory T cell differentiation	6.569253e-4
GO:0035441	cell migration involved in vasculogenesis	6.594970e-4
GO:0048662	negative regulation of smooth muscle cell proliferation	6.621576e-4
GO:0071299	cellular response to vitamin A	6.679874e-4
GO:0033559	unsaturated fatty acid metabolic process	6.695987e-4
GO:0009988	cell-cell recognition	6.707524e-4
GO:0030836	positive regulation of actin filament depolymerization	7.006179e-4
GO:0030299	intestinal cholesterol absorption	7.078851e-4
GO:0003205	cardiac chamber development	7.252053e-4
GO:0021764	amygdala development	7.441473e-4
GO:0002507	tolerance induction	7.448902e-4
GO:0006284	base-excision repair	7.535853e-4
GO:0051489	regulation of filopodium assembly	7.850729e-4
GO:0001822	kidney development	7.870746e-4
GO:0002920	regulation of humoral immune response	7.880865e-4
GO:0042538	hyperosmotic salinity response	7.981287e-4
GO:0032602	chemokine production	7.981287e-4
GO:0009214	cyclic nucleotide catabolic process	8.020045e-4
GO:0051182	coenzyme transport	8.025057e-4
GO:0007422	peripheral nervous system development	8.039113e-4
GO:0045136	development of secondary sexual characteristics	8.146353e-4
GO:0046543	development of secondary female sexual characteristics	8.184373e-4
GO:0048524	positive regulation of viral reproduction	8.234229e-4
GO:0006690	icosanoid metabolic process	8.422059e-4
GO:0002439	chronic inflammatory response to antigenic stimulus	8.719348e-4
GO:0048384	retinoic acid receptor signaling pathway	8.764651e-4
GO:0006198	cAMP catabolic process	8.798576e-4
GO:0006285	base-excision repair, AP site formation	8.880325e-4
GO:0031643	positive regulation of myelination	8.905344e-4
GO:0009394	2'-deoxyribonucleotide metabolic process	8.911945e-4
GO:0002819	regulation of adaptive immune response	8.975900e-4
GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly	9.111680e-4
GO:0006308	DNA catabolic process	9.399291e-4
GO:0001776	leukocyte homeostasis	9.663088e-4
GO:0006325	chromatin organization	9.706590e-4
GO:0005978	glycogen biosynthetic process	9.930514e-4
GO:0045843	negative regulation of striated muscle tissue development	9.948717e-4
GO:0046641	positive regulation of alpha-beta T cell proliferation	1.002973e-3
GO:0001773	myeloid dendritic cell activation	1.002973e-3
GO:0002328	pro-B cell differentiation	1.009544e-3
GO:0070845	polyubiquitinated misfolded protein transport	1.032048e-3
GO:0048295	positive regulation of isotype switching to IgE isotypes	1.032048e-3
GO:0002708	positive regulation of lymphocyte mediated immunity	1.045291e-3
GO:0034224	cellular response to zinc ion starvation	1.056806e-3
GO:0071585	detoxification of cadmium ion	1.056806e-3
GO:0060033	anatomical structure regression	1.056922e-3
GO:0033189	response to vitamin A	1.068651e-3
GO:2000252	negative regulation of feeding behavior	1.080396e-3
GO:0070922	small RNA loading onto RISC	1.080396e-3
GO:0060209	estrus	1.080396e-3
GO:0034144	negative regulation of toll-like receptor 4 signaling pathway	1.083764e-3
GO:0090291	negative regulation of osteoclast proliferation	1.084570e-3
GO:2000347	positive regulation of hepatocyte proliferation	1.084570e-3
GO:2000349	negative regulation of CD40 signaling pathway	1.084570e-3
GO:0072573	tolerance induction to lipopolysaccharide	1.084570e-3
GO:0034148	negative regulation of toll-like receptor 5 signaling pathway	1.084570e-3
GO:0070429	negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	1.084570e-3
GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	1.084570e-3
GO:0001782	B cell homeostasis	1.085473e-3
GO:0042506	tyrosine phosphorylation of Stat5 protein	1.090399e-3
GO:0043114	regulation of vascular permeability	1.091216e-3
GO:0046634	regulation of alpha-beta T cell activation	1.105343e-3
GO:0055009	atrial cardiac muscle tissue morphogenesis	1.106596e-3
GO:0032743	positive regulation of interleukin-2 production	1.110350e-3
GO:0071300	cellular response to retinoic acid	1.136203e-3
GO:0071954	chemokine (C-C motif) ligand 11 production	1.181951e-3
GO:2000525	positive regulation of T cell costimulation	1.181951e-3
GO:0035712	T-helper 2 cell activation	1.181951e-3
GO:0035708	interleukin-4-dependent isotype switching to IgE isotypes	1.181951e-3
GO:0002215	defense response to nematode	1.181951e-3
GO:0035709	memory T cell activation	1.181951e-3
GO:0045652	regulation of megakaryocyte differentiation	1.214591e-3
GO:0010616	negative regulation of cardiac muscle adaptation	1.222165e-3
GO:2000108	positive regulation of leukocyte apoptosis	1.249103e-3
GO:0060322	head development	1.254835e-3
GO:0002885	positive regulation of hypersensitivity	1.282910e-3
GO:0006891	intra-Golgi vesicle-mediated transport	1.329927e-3
GO:0010822	positive regulation of mitochondrion organization	1.330043e-3
GO:0007379	segment specification	1.346333e-3
GO:0034199	activation of protein kinase A activity	1.357352e-3
GO:0002573	myeloid leukocyte differentiation	1.364007e-3
GO:0060430	lung saccule development	1.365629e-3
GO:0048880	sensory system development	1.365629e-3
GO:0002260	lymphocyte homeostasis	1.389027e-3
GO:0008156	negative regulation of DNA replication	1.392529e-3
GO:0051591	response to cAMP	1.394837e-3
GO:0007225	patched ligand maturation	1.412010e-3
GO:0048545	response to steroid hormone stimulus	1.442321e-3
GO:0016559	peroxisome fission	1.447370e-3
GO:0032663	regulation of interleukin-2 production	1.465472e-3
GO:0009792	embryo development ending in birth or egg hatching	1.494930e-3
GO:0002639	positive regulation of immunoglobulin production	1.512716e-3
GO:0050688	regulation of defense response to virus	1.517368e-3
GO:0051299	centrosome separation	1.523496e-3
GO:0097070	ductus arteriosus closure	1.528256e-3
GO:0032674	regulation of interleukin-5 production	1.561632e-3
GO:0060312	regulation of blood vessel remodeling	1.561981e-3
GO:0003002	regionalization	1.566206e-3
GO:0015074	DNA integration	1.567113e-3
GO:0045765	regulation of angiogenesis	1.596048e-3
GO:0003231	cardiac ventricle development	1.597481e-3
GO:0043009	chordate embryonic development	1.617717e-3
GO:0032981	mitochondrial respiratory chain complex I assembly	1.628916e-3
GO:0090307	spindle assembly involved in mitosis	1.630987e-3
GO:0002702	positive regulation of production of molecular mediator of immune response	1.636149e-3
GO:0043011	myeloid dendritic cell differentiation	1.656968e-3
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	1.656992e-3
GO:0001834	trophectodermal cell proliferation	1.684965e-3
GO:0046731	passive induction of host immune response by virus	1.714753e-3
GO:0070904	transepithelial L-ascorbic acid transport	1.726391e-3
GO:0003279	cardiac septum development	1.763105e-3
GO:0006368	transcription elongation from RNA polymerase II promoter	1.782873e-3
GO:0051014	actin filament severing	1.788863e-3
GO:0009186	deoxyribonucleoside diphosphate metabolic process	1.800009e-3
GO:0015939	pantothenate metabolic process	1.804991e-3
GO:0032845	negative regulation of homeostatic process	1.811427e-3
GO:0034136	negative regulation of toll-like receptor 2 signaling pathway	1.840174e-3
GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway	1.905727e-3
GO:0008049	male courtship behavior	1.920759e-3
GO:0010734	negative regulation of protein glutathionylation	1.920759e-3
GO:0060678	dichotomous subdivision of terminal units involved in ureteric bud branching	1.978345e-3
GO:0032856	activation of Ras GTPase activity	1.992169e-3
GO:0072661	protein targeting to plasma membrane	1.992246e-3
GO:0042769	DNA damage response, detection of DNA damage	1.995503e-3
GO:2000016	negative regulation of determination of dorsal identity	2.022563e-3
GO:0071803	positive regulation of podosome assembly	2.031882e-3
GO:0055089	fatty acid homeostasis	2.031882e-3
GO:0051142	positive regulation of NK T cell proliferation	2.031882e-3
GO:0006707	cholesterol catabolic process	2.038914e-3
GO:0051930	regulation of sensory perception of pain	2.045321e-3
GO:0010107	potassium ion import	2.058648e-3
GO:0030431	sleep	2.146901e-3
GO:0002437	inflammatory response to antigenic stimulus	2.164473e-3
GO:0046514	ceramide catabolic process	2.165274e-3
GO:0046640	regulation of alpha-beta T cell proliferation	2.173608e-3
GO:0044241	lipid digestion	2.177942e-3
GO:2000758	positive regulation of peptidyl-lysine acetylation	2.181464e-3
GO:0003357	noradrenergic neuron differentiation	2.233201e-3
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	2.241710e-3
GO:0006983	ER overload response	2.259521e-3
GO:0034721	histone H3-K4 demethylation, trimethyl-H3-K4-specific	2.270811e-3
GO:0071107	response to parathyroid hormone stimulus	2.270829e-3
GO:0043401	steroid hormone mediated signaling pathway	2.291259e-3
GO:0002250	adaptive immune response	2.299313e-3
GO:0035865	cellular response to potassium ion	2.322713e-3
GO:0034651	cortisol biosynthetic process	2.322713e-3
GO:0032342	aldosterone biosynthetic process	2.322713e-3
GO:0000717	nucleotide-excision repair, DNA duplex unwinding	2.322713e-3
GO:0060324	face development	2.324904e-3
GO:0051491	positive regulation of filopodium assembly	2.354243e-3
GO:0007079	mitotic chromosome movement towards spindle pole	2.422467e-3
GO:0046635	positive regulation of alpha-beta T cell activation	2.455431e-3
GO:0003289	atrial septum primum morphogenesis	2.504461e-3
GO:0035117	embryonic arm morphogenesis	2.514337e-3
GO:0030324	lung development	2.523090e-3
GO:0042363	fat-soluble vitamin catabolic process	2.549103e-3
GO:0030208	dermatan sulfate biosynthetic process	2.603958e-3
GO:0002051	osteoblast fate commitment	2.603958e-3
GO:0021524	visceral motor neuron differentiation	2.603958e-3
GO:0002922	positive regulation of humoral immune response	2.623046e-3
GO:2000427	positive regulation of apoptotic cell clearance	2.663535e-3
GO:0006367	transcription initiation from RNA polymerase II promoter	2.672657e-3
GO:0048536	spleen development	2.678528e-3
GO:0007611	learning or memory	2.682594e-3
GO:0071731	response to nitric oxide	2.700377e-3
GO:0010226	response to lithium ion	2.770877e-3
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	2.803473e-3
GO:0015993	molecular hydrogen transport	2.805213e-3
GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus	2.819933e-3
GO:0051412	response to corticosterone stimulus	2.835891e-3
GO:0060591	chondroblast differentiation	2.863881e-3
GO:0046521	sphingoid catabolic process	2.908562e-3
GO:0022600	digestive system process	2.925566e-3
GO:0035418	protein localization to synapse	2.941660e-3
GO:0032464	positive regulation of protein homooligomerization	2.941660e-3
GO:0000301	retrograde transport, vesicle recycling within Golgi	2.952922e-3
GO:0032526	response to retinoic acid	2.964755e-3
GO:0046069	cGMP catabolic process	2.978513e-3
GO:0002520	immune system development	2.985171e-3
GO:0045943	positive regulation of transcription from RNA polymerase I promoter	2.991459e-3
GO:0019369	arachidonic acid metabolic process	3.011903e-3
GO:0007638	mechanosensory behavior	3.025518e-3
GO:0009262	deoxyribonucleotide metabolic process	3.072224e-3
GO:0032205	negative regulation of telomere maintenance	3.078690e-3
GO:0007631	feeding behavior	3.125200e-3
GO:0007567	parturition	3.125264e-3
GO:0003206	cardiac chamber morphogenesis	3.146422e-3
GO:0033504	floor plate development	3.167132e-3
GO:0033599	regulation of mammary gland epithelial cell proliferation	3.168391e-3
GO:0009113	purine base biosynthetic process	3.179546e-3
GO:0034116	positive regulation of heterotypic cell-cell adhesion	3.182987e-3
GO:0008039	synaptic target recognition	3.229146e-3
GO:2000171	negative regulation of dendrite development	3.276578e-3
GO:0071577	zinc ion transmembrane transport	3.284207e-3
GO:0001916	positive regulation of T cell mediated cytotoxicity	3.292727e-3
GO:0001957	intramembranous ossification	3.298742e-3
GO:0008033	tRNA processing	3.306649e-3
GO:0019322	pentose biosynthetic process	3.337825e-3
GO:0006268	DNA unwinding involved in replication	3.337825e-3
GO:0033108	mitochondrial respiratory chain complex assembly	3.353947e-3
GO:0006399	tRNA metabolic process	3.360600e-3
GO:0010900	negative regulation of phosphatidylcholine catabolic process	3.400366e-3
GO:0090231	regulation of spindle checkpoint	3.415645e-3
GO:0051925	regulation of calcium ion transport via voltage-gated calcium channel activity	3.471411e-3
GO:0044236	multicellular organismal metabolic process	3.538897e-3
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	3.547104e-3
GO:0015742	alpha-ketoglutarate transport	3.547104e-3
GO:0016568	chromatin modification	3.573463e-3
GO:0000720	pyrimidine dimer repair by nucleotide-excision repair	3.588439e-3
GO:0045063	T-helper 1 cell differentiation	3.600164e-3
GO:0007193	inhibition of adenylate cyclase activity by G-protein signaling pathway	3.614667e-3
GO:0002883	regulation of hypersensitivity	3.617884e-3
GO:0014894	response to denervation involved in regulation of muscle adaptation	3.651277e-3
GO:0051594	detection of glucose	3.651277e-3
GO:0070389	chaperone cofactor-dependent protein refolding	3.709548e-3
GO:0033131	regulation of glucokinase activity	3.845001e-3
GO:0061038	uterus morphogenesis	3.871659e-3
GO:0035565	regulation of pronephros size	3.896679e-3
GO:0039020	pronephric nephron tubule development	3.896679e-3
GO:0035545	determination of left/right asymmetry in nervous system	3.896679e-3
GO:0050748	negative regulation of lipoprotein metabolic process	4.234048e-3
GO:0043932	ossification involved in bone remodeling	4.234048e-3
GO:0050792	regulation of viral reproduction	4.262462e-3
GO:0051350	negative regulation of lyase activity	4.318576e-3
GO:0051901	positive regulation of mitochondrial depolarization	4.336737e-3
GO:0043500	muscle adaptation	4.363933e-3
GO:0008360	regulation of cell shape	4.371362e-3
GO:0009436	glyoxylate catabolic process	4.423634e-3
GO:0006420	arginyl-tRNA aminoacylation	4.433229e-3
GO:0006927	transformed cell apoptosis	4.494044e-3
GO:0050862	positive regulation of T cell receptor signaling pathway	4.494044e-3
GO:0014009	glial cell proliferation	4.540491e-3
GO:0030323	respiratory tube development	4.558090e-3
GO:0006479	protein methylation	4.603975e-3
GO:0071415	cellular response to purine-containing compound	4.670341e-3
GO:0030422	production of siRNA involved in RNA interference	4.706950e-3
GO:0003017	lymph circulation	4.706950e-3
GO:2000111	positive regulation of macrophage apoptosis	4.732870e-3
GO:0009449	gamma-aminobutyric acid biosynthetic process	4.746952e-3
GO:0003184	pulmonary valve morphogenesis	4.746952e-3
GO:0003139	secondary heart field specification	4.750641e-3
GO:0070646	protein modification by small protein removal	4.770194e-3
GO:0007512	adult heart development	4.878486e-3
GO:0016339	calcium-dependent cell-cell adhesion	4.902622e-3
GO:0006281	DNA repair	4.938422e-3
GO:0042255	ribosome assembly	4.942893e-3
GO:0045654	positive regulation of megakaryocyte differentiation	4.950794e-3
GO:0009612	response to mechanical stimulus	4.965973e-3
GO:0006351	transcription, DNA-dependent	5.008837e-3
GO:2000035	regulation of stem cell division	5.040904e-3
GO:0001958	endochondral ossification	5.062397e-3
GO:0006014	D-ribose metabolic process	5.068105e-3
GO:0048484	enteric nervous system development	5.104657e-3
GO:0010950	positive regulation of endopeptidase activity	5.126086e-3
GO:0021517	ventral spinal cord development	5.165957e-3
GO:0043900	regulation of multi-organism process	5.194383e-3
GO:0035710	CD4-positive, alpha-beta T cell activation	5.198495e-3
GO:0034393	positive regulation of smooth muscle cell apoptosis	5.232253e-3
GO:0043653	mitochondrial fragmentation involved in apoptosis	5.237668e-3
GO:0009880	embryonic pattern specification	5.406406e-3
GO:0031223	auditory behavior	5.469605e-3
GO:0048534	hemopoietic or lymphoid organ development	5.480925e-3
GO:0042093	T-helper cell differentiation	5.535670e-3
GO:0032700	negative regulation of interleukin-17 production	5.535670e-3
GO:0001569	patterning of blood vessels	5.543595e-3
GO:0046060	dATP metabolic process	5.557184e-3
GO:0060005	vestibular reflex	5.578632e-3
GO:0090200	positive regulation of release of cytochrome c from mitochondria	5.609532e-3
GO:0034140	negative regulation of toll-like receptor 3 signaling pathway	5.637579e-3
GO:0060348	bone development	5.667160e-3
GO:0070536	protein K63-linked deubiquitination	5.730548e-3
GO:0048935	peripheral nervous system neuron development	5.759887e-3
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	5.764103e-3
GO:0016046	detection of fungus	5.764103e-3
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	5.764103e-3
GO:0016579	protein deubiquitination	5.835935e-3
GO:0009153	purine deoxyribonucleotide biosynthetic process	5.848189e-3
GO:0042256	mature ribosome assembly	5.848189e-3
GO:0043615	astrocyte cell migration	6.030833e-3
GO:0071824	protein-DNA complex subunit organization	6.069592e-3
GO:0071295	cellular response to vitamin	6.107761e-3
GO:0030862	positive regulation of polarized epithelial cell differentiation	6.150894e-3
GO:0034728	nucleosome organization	6.156250e-3
GO:0009451	RNA modification	6.183547e-3
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	6.188208e-3
GO:0072001	renal system development	6.195356e-3
GO:0009187	cyclic nucleotide metabolic process	6.199078e-3
GO:0050691	regulation of defense response to virus by host	6.207292e-3
GO:0009223	pyrimidine deoxyribonucleotide catabolic process	6.207938e-3
GO:0007194	negative regulation of adenylate cyclase activity	6.237931e-3
GO:0032740	positive regulation of interleukin-17 production	6.246202e-3
GO:0060465	pharynx development	6.272067e-3
GO:0043148	mitotic spindle stabilization	6.272067e-3
GO:0034378	chylomicron assembly	6.272067e-3
GO:0007612	learning	6.356947e-3
GO:0009651	response to salt stress	6.408621e-3
GO:0014912	negative regulation of smooth muscle cell migration	6.429656e-3
GO:0046323	glucose import	6.481607e-3
GO:0045008	depyrimidination	6.481607e-3
GO:0033133	positive regulation of glucokinase activity	6.481607e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0072178	nephric duct morphogenesis	4.313148e-13
GO:0072176	nephric duct development	6.687174e-12
GO:0072179	nephric duct formation	9.242627e-11
GO:0072182	regulation of nephron tubule epithelial cell differentiation	9.846018e-11
GO:2000696	regulation of epithelial cell differentiation involved in kidney development	2.233295e-10
GO:0090185	negative regulation of kidney development	2.253105e-10
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	4.853178e-10
GO:0016579	protein deubiquitination	7.191764e-10
GO:0048568	embryonic organ development	9.069764e-10
GO:0072098	anterior/posterior pattern specification involved in kidney development	2.482582e-9
GO:0048389	intermediate mesoderm development	2.482582e-9
GO:0007501	mesodermal cell fate specification	6.309232e-9
GO:0070646	protein modification by small protein removal	7.128739e-9
GO:0003382	epithelial cell morphogenesis	1.201655e-8
GO:0048706	embryonic skeletal system development	1.249430e-8
GO:0001823	mesonephros development	1.392039e-8
GO:0051093	negative regulation of developmental process	1.628801e-8
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	1.976387e-8
GO:0072161	mesenchymal cell differentiation involved in kidney development	2.383261e-8
GO:0000281	cytokinesis after mitosis	2.605481e-8
GO:0001710	mesodermal cell fate commitment	3.583503e-8
GO:0019255	glucose 1-phosphate metabolic process	5.590830e-8
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB cascade	5.725087e-8
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	6.568497e-8
GO:0000082	G1/S transition of mitotic cell cycle	8.102402e-8
GO:0072189	ureter development	8.692644e-8
GO:0090183	regulation of kidney development	9.173434e-8
GO:0060548	negative regulation of cell death	9.534729e-8
GO:0072215	regulation of metanephros development	1.145278e-7
GO:0072078	nephron tubule morphogenesis	1.537420e-7
GO:0043066	negative regulation of apoptosis	1.690161e-7
GO:0071360	cellular response to exogenous dsRNA	1.991573e-7
GO:0048793	pronephros development	2.846198e-7
GO:0060795	cell fate commitment involved in formation of primary germ layers	2.966754e-7
GO:0043583	ear development	3.028755e-7
GO:0043069	negative regulation of programmed cell death	3.248332e-7
GO:0072172	mesonephric tubule formation	3.457172e-7
GO:0007423	sensory organ development	3.889391e-7
GO:0032649	regulation of interferon-gamma production	4.305120e-7
GO:0042421	norepinephrine biosynthetic process	5.153295e-7
GO:0031929	TOR signaling cascade	5.657605e-7
GO:0072171	mesonephric tubule morphogenesis	5.967274e-7
GO:2000352	negative regulation of endothelial cell apoptosis	6.031643e-7
GO:0032088	negative regulation of NF-kappaB transcription factor activity	6.084213e-7
GO:0072080	nephron tubule development	7.208975e-7
GO:0010604	positive regulation of macromolecule metabolic process	7.438275e-7
GO:0070167	regulation of biomineral tissue development	1.080574e-6
GO:0033085	negative regulation of T cell differentiation in thymus	1.164617e-6
GO:0051249	regulation of lymphocyte activation	1.201410e-6
GO:0072183	negative regulation of nephron tubule epithelial cell differentiation	1.249816e-6
GO:0043330	response to exogenous dsRNA	1.250284e-6
GO:0018924	mandelate metabolic process	1.303452e-6
GO:0061290	canonical Wnt receptor signaling pathway involved in metanephric kidney development	1.322768e-6
GO:0006355	regulation of transcription, DNA-dependent	1.380792e-6
GO:0060272	embryonic skeletal joint morphogenesis	1.447361e-6
GO:0045596	negative regulation of cell differentiation	1.593324e-6
GO:0010159	specification of organ position	1.903475e-6
GO:0072190	ureter urothelium development	1.929583e-6
GO:0051241	negative regulation of multicellular organismal process	2.019951e-6
GO:0030500	regulation of bone mineralization	2.101672e-6
GO:0061333	renal tubule morphogenesis	2.138288e-6
GO:0001822	kidney development	2.514767e-6
GO:2000611	positive regulation of thyroid hormone generation	2.599631e-6
GO:0051496	positive regulation of stress fiber assembly	2.662602e-6
GO:0009893	positive regulation of metabolic process	2.862273e-6
GO:0031325	positive regulation of cellular metabolic process	3.060177e-6
GO:0034728	nucleosome organization	3.119696e-6
GO:0043201	response to leucine	3.235873e-6
GO:0072498	embryonic skeletal joint development	3.301250e-6
GO:0001886	endothelial cell morphogenesis	3.564697e-6
GO:0072197	ureter morphogenesis	3.572713e-6
GO:0007250	activation of NF-kappaB-inducing kinase activity	3.764522e-6
GO:0003158	endothelium development	4.313207e-6
GO:0048562	embryonic organ morphogenesis	4.521627e-6
GO:0090005	negative regulation of establishment of protein localization in plasma membrane	4.655230e-6
GO:0061326	renal tubule development	4.727162e-6
GO:0051026	chiasma assembly	4.839637e-6
GO:2000826	regulation of heart morphogenesis	5.224334e-6
GO:0072202	cell differentiation involved in metanephros development	5.228694e-6
GO:0051173	positive regulation of nitrogen compound metabolic process	5.710662e-6
GO:0046324	regulation of glucose import	6.383453e-6
GO:0009889	regulation of biosynthetic process	7.125498e-6
GO:0072001	renal system development	7.486739e-6
GO:0072044	collecting duct development	7.848507e-6
GO:0035307	positive regulation of protein dephosphorylation	8.397366e-6
GO:0050953	sensory perception of light stimulus	9.042044e-6
GO:0031326	regulation of cellular biosynthetic process	9.464831e-6
GO:0048260	positive regulation of receptor-mediated endocytosis	9.508769e-6
GO:0060993	kidney morphogenesis	9.754367e-6
GO:0072141	renal interstitial cell development	1.006325e-5
GO:0030421	defecation	1.015522e-5
GO:0072259	metanephric interstitial cell development	1.021944e-5
GO:0090094	metanephric cap mesenchymal cell proliferation involved in metanephros development	1.021944e-5
GO:0072208	metanephric smooth muscle tissue development	1.021944e-5
GO:0072184	renal vesicle progenitor cell differentiation	1.021944e-5
GO:0072169	specification of posterior mesonephric tubule identity	1.021944e-5
GO:0072168	specification of anterior mesonephric tubule identity	1.021944e-5
GO:0035306	positive regulation of dephosphorylation	1.047117e-5
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	1.061655e-5
GO:0001819	positive regulation of cytokine production	1.069990e-5
GO:0048483	autonomic nervous system development	1.148552e-5
GO:0003279	cardiac septum development	1.192007e-5
GO:0000079	regulation of cyclin-dependent protein kinase activity	1.199690e-5
GO:0010556	regulation of macromolecule biosynthetic process	1.231385e-5
GO:0035564	regulation of kidney size	1.258231e-5
GO:0021528	commissural neuron differentiation in spinal cord	1.295867e-5
GO:2000112	regulation of cellular macromolecule biosynthetic process	1.329629e-5
GO:0007162	negative regulation of cell adhesion	1.344576e-5
GO:0010092	specification of organ identity	1.351781e-5
GO:0007601	visual perception	1.358279e-5
GO:0010616	negative regulation of cardiac muscle adaptation	1.375580e-5
GO:0043526	neuroprotection	1.387629e-5
GO:0003281	ventricular septum development	1.486942e-5
GO:0034374	low-density lipoprotein particle remodeling	1.676330e-5
GO:0061005	cell differentiation involved in kidney development	1.705592e-5
GO:0072088	nephron epithelium morphogenesis	1.817160e-5
GO:2000106	regulation of leukocyte apoptosis	1.840691e-5
GO:0045893	positive regulation of transcription, DNA-dependent	1.902556e-5
GO:0007379	segment specification	1.916614e-5
GO:0051252	regulation of RNA metabolic process	2.078450e-5
GO:2000351	regulation of endothelial cell apoptosis	2.185052e-5
GO:0060695	negative regulation of cholesterol transporter activity	2.333533e-5
GO:0015759	beta-glucoside transport	2.333533e-5
GO:0018027	peptidyl-lysine dimethylation	2.333836e-5
GO:0048523	negative regulation of cellular process	2.341160e-5
GO:0051492	regulation of stress fiber assembly	2.353528e-5
GO:0034441	plasma lipoprotein particle oxidation	2.378063e-5
GO:0072079	nephron tubule formation	2.480492e-5
GO:2000664	positive regulation of interleukin-5 secretion	2.484213e-5
GO:2000734	negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation	2.484213e-5
GO:2000703	negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation	2.484213e-5
GO:2000667	positive regulation of interleukin-13 secretion	2.484213e-5
GO:0001806	type IV hypersensitivity	2.484213e-5
GO:0021568	rhombomere 2 development	2.484213e-5
GO:0060374	mast cell differentiation	2.484213e-5
GO:2000607	negative regulation of cell proliferation involved in mesonephros development	2.484213e-5
GO:0001958	endochondral ossification	2.591570e-5
GO:0055091	phospholipid homeostasis	2.667044e-5
GO:0002634	regulation of germinal center formation	2.709942e-5
GO:0072207	metanephric epithelium development	2.771868e-5
GO:0003215	cardiac right ventricle morphogenesis	2.803217e-5
GO:0048332	mesoderm morphogenesis	2.814586e-5
GO:0032703	negative regulation of interleukin-2 production	2.815329e-5
GO:0071173	spindle assembly checkpoint	3.144452e-5
GO:0048839	inner ear development	3.159877e-5
GO:0072009	nephron epithelium development	3.173877e-5
GO:0070432	regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	3.177916e-5
GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	3.177916e-5
GO:0035304	regulation of protein dephosphorylation	3.309656e-5
GO:0048641	regulation of skeletal muscle tissue development	3.314652e-5
GO:0032715	negative regulation of interleukin-6 production	3.324845e-5
GO:0072177	mesonephric duct development	3.456114e-5
GO:0045581	negative regulation of T cell differentiation	3.573513e-5
GO:0060536	cartilage morphogenesis	3.736071e-5
GO:0043496	regulation of protein homodimerization activity	3.759123e-5
GO:0002456	T cell mediated immunity	4.259580e-5
GO:0006551	leucine metabolic process	4.276693e-5
GO:0051254	positive regulation of RNA metabolic process	4.386785e-5
GO:0016191	synaptic vesicle uncoating	4.456359e-5
GO:0003170	heart valve development	4.488740e-5
GO:0051250	negative regulation of lymphocyte activation	4.826818e-5
GO:0072198	mesenchymal cell proliferation involved in ureter development	4.884561e-5
GO:0072200	negative regulation of mesenchymal cell proliferation involved in ureter development	4.884561e-5
GO:0072138	mesenchymal cell proliferation involved in ureteric bud development	4.884561e-5
GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis	4.884561e-5
GO:0072192	ureter epithelial cell differentiation	4.884561e-5
GO:2000137	negative regulation of cell proliferation involved in heart morphogenesis	4.884561e-5
GO:2000007	negative regulation of metanephric comma-shaped body morphogenesis	4.884561e-5
GO:2000005	negative regulation of metanephric S-shaped body morphogenesis	4.884561e-5
GO:0090194	negative regulation of glomerulus development	4.884561e-5
GO:0072101	specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway	4.884561e-5
GO:0060503	bud dilation involved in lung branching	4.884561e-5
GO:0055020	positive regulation of cardiac muscle fiber development	4.884561e-5
GO:0007500	mesodermal cell fate determination	4.884561e-5
GO:0072097	negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway	4.884561e-5
GO:0060502	epithelial cell proliferation involved in lung morphogenesis	4.884561e-5
GO:0048392	intermediate mesodermal cell differentiation	4.884561e-5
GO:0061155	pulmonary artery endothelial tube morphogenesis	4.884561e-5
GO:0071893	BMP signaling pathway involved in nephric duct formation	4.884561e-5
GO:0061151	BMP signaling pathway involved in renal system segmentation	4.884561e-5
GO:0061149	BMP signaling pathway involved in ureter morphogenesis	4.884561e-5
GO:0072282	metanephric nephron tubule morphogenesis	5.018812e-5
GO:0045737	positive regulation of cyclin-dependent protein kinase activity	5.203024e-5
GO:0003266	regulation of secondary heart field cardioblast proliferation	5.283478e-5
GO:0032516	positive regulation of phosphoprotein phosphatase activity	5.319933e-5
GO:2000647	negative regulation of stem cell proliferation	5.362217e-5
GO:0070563	negative regulation of vitamin D receptor signaling pathway	5.362217e-5
GO:0010839	negative regulation of keratinocyte proliferation	5.362217e-5
GO:0035921	desmosome disassembly	5.362217e-5
GO:0072162	metanephric mesenchymal cell differentiation	5.566254e-5
GO:0043331	response to dsRNA	5.703320e-5
GO:0045580	regulation of T cell differentiation	5.954192e-5
GO:0051276	chromosome organization	5.996903e-5
GO:0009620	response to fungus	6.037770e-5
GO:0072003	kidney rudiment formation	6.095109e-5
GO:0001656	metanephros development	6.229338e-5
GO:0019219	regulation of nucleobase-containing compound metabolic process	6.433931e-5
GO:0051171	regulation of nitrogen compound metabolic process	6.525241e-5
GO:0007252	I-kappaB phosphorylation	6.572058e-5
GO:0010557	positive regulation of macromolecule biosynthetic process	6.735209e-5
GO:0035303	regulation of dephosphorylation	6.747600e-5
GO:0072073	kidney epithelium development	6.781908e-5
GO:0071715	icosanoid transport	6.841583e-5
GO:0030279	negative regulation of ossification	7.410386e-5
GO:0072170	metanephric tubule development	7.518919e-5
GO:0072224	metanephric glomerulus development	7.752632e-5
GO:0006323	DNA packaging	7.757723e-5
GO:0002118	aggressive behavior	7.838373e-5
GO:0043009	chordate embryonic development	7.886544e-5
GO:0071874	cellular response to norepinephrine stimulus	8.009602e-5
GO:0002250	adaptive immune response	8.020922e-5
GO:0050865	regulation of cell activation	8.100984e-5
GO:0032774	RNA biosynthetic process	8.191694e-5
GO:0003231	cardiac ventricle development	8.253413e-5
GO:0072205	metanephric collecting duct development	8.355760e-5
GO:0045084	positive regulation of interleukin-12 biosynthetic process	8.425640e-5
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	8.456397e-5
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	8.456397e-5
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	8.456397e-5
GO:0032707	negative regulation of interleukin-23 production	8.456397e-5
GO:0045362	positive regulation of interleukin-1 biosynthetic process	8.456397e-5
GO:0009891	positive regulation of biosynthetic process	8.460140e-5
GO:0021532	neural tube patterning	8.686482e-5
GO:0002293	alpha-beta T cell differentiation involved in immune response	8.690915e-5
GO:0048642	negative regulation of skeletal muscle tissue development	8.732195e-5
GO:0031328	positive regulation of cellular biosynthetic process	8.854415e-5
GO:0001709	cell fate determination	8.922754e-5
GO:0071480	cellular response to gamma radiation	8.949763e-5
GO:0042249	establishment of planar polarity of embryonic epithelium	9.020071e-5
GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration	9.474933e-5
GO:0071359	cellular response to dsRNA	9.524850e-5
GO:0032233	positive regulation of actin filament bundle assembly	9.592184e-5
GO:0006351	transcription, DNA-dependent	9.631132e-5
GO:0035566	regulation of metanephros size	9.780877e-5
GO:0000103	sulfate assimilation	1.037543e-4
GO:0072107	positive regulation of ureteric bud formation	1.046469e-4
GO:0072095	regulation of branch elongation involved in ureteric bud branching	1.078155e-4
GO:0070168	negative regulation of biomineral tissue development	1.101502e-4
GO:0002694	regulation of leukocyte activation	1.125989e-4
GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway	1.139467e-4
GO:0034641	cellular nitrogen compound metabolic process	1.167328e-4
GO:0051055	negative regulation of lipid biosynthetic process	1.194133e-4
GO:0003179	heart valve morphogenesis	1.194133e-4
GO:0070562	regulation of vitamin D receptor signaling pathway	1.217560e-4
GO:0009792	embryo development ending in birth or egg hatching	1.238105e-4
GO:0001818	negative regulation of cytokine production	1.276324e-4
GO:0045911	positive regulation of DNA recombination	1.294604e-4
GO:0003211	cardiac ventricle formation	1.302757e-4
GO:0072234	metanephric nephron tubule development	1.309168e-4
GO:0060231	mesenchymal to epithelial transition	1.309168e-4
GO:0032331	negative regulation of chondrocyte differentiation	1.387200e-4
GO:0006334	nucleosome assembly	1.397146e-4
GO:0031954	positive regulation of protein autophosphorylation	1.416674e-4
GO:0030502	negative regulation of bone mineralization	1.422733e-4
GO:0045764	positive regulation of cellular amino acid metabolic process	1.436778e-4
GO:0002287	alpha-beta T cell activation involved in immune response	1.444262e-4
GO:0003205	cardiac chamber development	1.457173e-4
GO:0045446	endothelial cell differentiation	1.476137e-4
GO:0097022	lymphocyte migration into lymph node	1.477026e-4
GO:0072610	interleukin-12 secretion	1.477026e-4
GO:0014043	negative regulation of neuron maturation	1.479505e-4
GO:0071599	otic vesicle development	1.496675e-4
GO:0061154	endothelial tube morphogenesis	1.524280e-4
GO:0061047	positive regulation of branching involved in lung morphogenesis	1.524280e-4
GO:0051453	regulation of intracellular pH	1.541050e-4
GO:0060363	cranial suture morphogenesis	1.573212e-4
GO:0071824	protein-DNA complex subunit organization	1.573845e-4
GO:0050482	arachidonic acid secretion	1.574338e-4
GO:0031577	spindle checkpoint	1.579999e-4
GO:0042471	ear morphogenesis	1.589181e-4
GO:0010628	positive regulation of gene expression	1.627120e-4
GO:0002320	lymphoid progenitor cell differentiation	1.680127e-4
GO:0010941	regulation of cell death	1.685791e-4
GO:0042415	norepinephrine metabolic process	1.687012e-4
GO:0042946	glucoside transport	1.724905e-4
GO:0035990	tendon cell differentiation	1.724905e-4
GO:0033128	negative regulation of histone phosphorylation	1.724905e-4
GO:0046717	acid secretion	1.755108e-4
GO:0072017	distal tubule development	1.783437e-4
GO:0045627	positive regulation of T-helper 1 cell differentiation	1.800788e-4
GO:0048704	embryonic skeletal system morphogenesis	1.840775e-4
GO:0050866	negative regulation of cell activation	1.855991e-4
GO:0010845	positive regulation of reciprocal meiotic recombination	1.889223e-4
GO:0035993	deltoid tuberosity development	1.917548e-4
GO:2000594	positive regulation of metanephric DCT cell differentiation	1.946011e-4
GO:0072305	negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis	1.946011e-4
GO:0039003	pronephric field specification	1.946011e-4
GO:0021542	dentate gyrus development	1.966320e-4
GO:0072180	mesonephric duct morphogenesis	2.024834e-4
GO:0001885	endothelial cell development	2.153042e-4
GO:0090304	nucleic acid metabolic process	2.223965e-4
GO:0030856	regulation of epithelial cell differentiation	2.227874e-4
GO:0072164	mesonephric tubule development	2.275768e-4
GO:0032736	positive regulation of interleukin-13 production	2.333703e-4
GO:0032963	collagen metabolic process	2.344053e-4
GO:0051216	cartilage development	2.364107e-4
GO:0008285	negative regulation of cell proliferation	2.365291e-4
GO:0097026	dendritic cell dendrite assembly	2.438936e-4
GO:0090074	negative regulation of protein homodimerization activity	2.438936e-4
GO:0014065	phosphatidylinositol 3-kinase cascade	2.447125e-4
GO:0045843	negative regulation of striated muscle tissue development	2.455997e-4
GO:0006139	nucleobase-containing compound metabolic process	2.492376e-4
GO:0042268	regulation of cytolysis	2.569135e-4
GO:0001817	regulation of cytokine production	2.573248e-4
GO:0032663	regulation of interleukin-2 production	2.611118e-4
GO:0032743	positive regulation of interleukin-2 production	2.723326e-4
GO:0090192	regulation of glomerulus development	2.736969e-4
GO:0032782	bile acid secretion	2.739184e-4
GO:0006780	uroporphyrinogen III biosynthetic process	2.739184e-4
GO:0003096	renal sodium ion transport	2.739184e-4
GO:0072300	positive regulation of metanephric glomerulus development	2.784279e-4
GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation	2.784279e-4
GO:0048298	positive regulation of isotype switching to IgA isotypes	2.784279e-4
GO:0050868	negative regulation of T cell activation	2.786939e-4
GO:0003207	cardiac chamber formation	2.837437e-4
GO:0007129	synapsis	2.879141e-4
GO:0045839	negative regulation of mitosis	2.907881e-4
GO:0061309	cardiac neural crest cell development involved in outflow tract morphogenesis	2.919238e-4
GO:0046326	positive regulation of glucose import	2.932708e-4
GO:0072028	nephron morphogenesis	2.971899e-4
GO:0072539	T-helper 17 cell differentiation	2.975674e-4
GO:0030221	basophil differentiation	2.975674e-4
GO:0072210	metanephric nephron development	3.009482e-4
GO:0033205	cell cycle cytokinesis	3.087965e-4
GO:0002695	negative regulation of leukocyte activation	3.280721e-4
GO:0030857	negative regulation of epithelial cell differentiation	3.289016e-4
GO:0002064	epithelial cell development	3.317515e-4
GO:0042476	odontogenesis	3.322572e-4
GO:0090184	positive regulation of kidney development	3.369827e-4
GO:0032733	positive regulation of interleukin-10 production	3.369827e-4
GO:0045620	negative regulation of lymphocyte differentiation	3.436202e-4
GO:0032814	regulation of natural killer cell activation	3.602561e-4
GO:0090189	regulation of branching involved in ureteric bud morphogenesis	3.625892e-4
GO:0045736	negative regulation of cyclin-dependent protein kinase activity	3.681641e-4
GO:0007602	phototransduction	3.692362e-4
GO:0032416	negative regulation of sodium:hydrogen antiporter activity	3.692826e-4
GO:0010002	cardioblast differentiation	3.732093e-4
GO:0010468	regulation of gene expression	3.740284e-4
GO:0032849	positive regulation of cellular pH reduction	3.807001e-4
GO:0006930	substrate-dependent cell migration, cell extension	3.814006e-4
GO:0009887	organ morphogenesis	3.831082e-4
GO:0045652	regulation of megakaryocyte differentiation	3.859559e-4
GO:0065001	specification of axis polarity	3.880032e-4
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	3.999995e-4
GO:0031589	cell-substrate adhesion	4.055570e-4
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	4.064439e-4
GO:0051145	smooth muscle cell differentiation	4.087741e-4
GO:0006325	chromatin organization	4.107729e-4
GO:0070374	positive regulation of ERK1 and ERK2 cascade	4.256006e-4
GO:0045619	regulation of lymphocyte differentiation	4.382287e-4
GO:2000319	regulation of T-helper 17 cell differentiation	4.425905e-4
GO:0034725	DNA replication-dependent nucleosome disassembly	4.425905e-4
GO:0050708	regulation of protein secretion	4.426308e-4
GO:0072289	metanephric nephron tubule formation	4.437264e-4
GO:0045844	positive regulation of striated muscle tissue development	4.515296e-4
GO:0003206	cardiac chamber morphogenesis	4.519605e-4
GO:0001707	mesoderm formation	4.528717e-4
GO:0010827	regulation of glucose transport	4.557171e-4
GO:0001825	blastocyst formation	4.593688e-4
GO:0048729	tissue morphogenesis	4.729504e-4
GO:0007613	memory	4.791444e-4
GO:0014041	regulation of neuron maturation	4.837813e-4
GO:0006333	chromatin assembly or disassembly	4.839631e-4
GO:0050793	regulation of developmental process	4.849054e-4
GO:0021930	cerebellar granule cell precursor proliferation	4.901363e-4
GO:0060065	uterus development	4.912794e-4
GO:0003139	secondary heart field specification	4.939739e-4
GO:0009996	negative regulation of cell fate specification	4.984019e-4
GO:0030641	regulation of cellular pH	5.046950e-4
GO:0070192	chromosome organization involved in meiosis	5.060562e-4
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	5.060562e-4
GO:0021591	ventricular system development	5.073999e-4
GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	5.136999e-4
GO:0006344	maintenance of chromatin silencing	5.221629e-4
GO:0002572	pro-T cell differentiation	5.221629e-4
GO:0001654	eye development	5.303715e-4
GO:0003208	cardiac ventricle morphogenesis	5.304980e-4
GO:0034115	negative regulation of heterotypic cell-cell adhesion	5.515674e-4
GO:0030903	notochord development	5.538242e-4
GO:0072074	kidney mesenchyme development	5.629060e-4
GO:0060255	regulation of macromolecule metabolic process	5.650502e-4
GO:0030220	platelet formation	5.749088e-4
GO:0006885	regulation of pH	5.832666e-4
GO:0051382	kinetochore assembly	6.021196e-4
GO:0045885	positive regulation of survival gene product expression	6.066120e-4
GO:0033364	mast cell secretory granule organization	6.129965e-4
GO:0072193	ureter smooth muscle cell differentiation	6.129965e-4
GO:0045833	negative regulation of lipid metabolic process	6.133944e-4
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	6.294945e-4
GO:0006807	nitrogen compound metabolic process	6.406488e-4
GO:0030278	regulation of ossification	6.516117e-4
GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	6.673954e-4
GO:0055067	monovalent inorganic cation homeostasis	6.903306e-4
GO:0051247	positive regulation of protein metabolic process	6.972566e-4
GO:0055025	positive regulation of cardiac muscle tissue development	7.049670e-4
GO:0032765	positive regulation of mast cell cytokine production	7.073715e-4
GO:0034635	glutathione transport	7.073715e-4
GO:0006437	tyrosyl-tRNA aminoacylation	7.073715e-4
GO:0002431	Fc receptor mediated stimulatory signaling pathway	7.073715e-4
GO:2000108	positive regulation of leukocyte apoptosis	7.119022e-4
GO:0010933	positive regulation of macrophage tolerance induction	7.145108e-4
GO:0035249	synaptic transmission, glutamatergic	7.248982e-4
GO:0032231	regulation of actin filament bundle assembly	7.260565e-4
GO:0048485	sympathetic nervous system development	7.367455e-4
GO:0032835	glomerulus development	7.395843e-4
GO:0046622	positive regulation of organ growth	7.505068e-4
GO:0006357	regulation of transcription from RNA polymerase II promoter	7.510183e-4
GO:0010463	mesenchymal cell proliferation	7.538630e-4
GO:0035308	negative regulation of protein dephosphorylation	7.561027e-4
GO:0072006	nephron development	7.563066e-4
GO:0048633	positive regulation of skeletal muscle tissue growth	7.686627e-4
GO:0006710	androgen catabolic process	7.686627e-4
GO:0006408	snRNA export from nucleus	7.686627e-4
GO:0044259	multicellular organismal macromolecule metabolic process	7.772234e-4
GO:0070244	negative regulation of thymocyte apoptosis	7.889696e-4
GO:0048484	enteric nervous system development	8.427370e-4
GO:0032754	positive regulation of interleukin-5 production	8.447706e-4
GO:0001878	response to yeast	8.547623e-4
GO:0043666	regulation of phosphoprotein phosphatase activity	8.586851e-4
GO:0045884	regulation of survival gene product expression	8.697315e-4
GO:0034446	substrate adhesion-dependent cell spreading	8.766049e-4
GO:0060675	ureteric bud morphogenesis	8.787614e-4
GO:0016246	RNA interference	8.924349e-4
GO:0060037	pharyngeal system development	8.939281e-4
GO:0048635	negative regulation of muscle organ development	9.003004e-4
GO:0060931	sinoatrial node cell development	9.016287e-4
GO:0003167	atrioventricular bundle cell differentiation	9.016287e-4
GO:0006991	response to sterol depletion	9.016287e-4
GO:0031323	regulation of cellular metabolic process	9.037450e-4
GO:0001501	skeletal system development	9.186770e-4
GO:0045653	negative regulation of megakaryocyte differentiation	9.210656e-4
GO:0021604	cranial nerve structural organization	9.235239e-4
GO:0071103	DNA conformation change	9.423755e-4
GO:0002149	hypochlorous acid biosynthetic process	9.459852e-4
GO:0045601	regulation of endothelial cell differentiation	9.667625e-4
GO:0061098	positive regulation of protein tyrosine kinase activity	9.709591e-4
GO:0032615	interleukin-12 production	9.753093e-4
GO:0031394	positive regulation of prostaglandin biosynthetic process	9.753093e-4
GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	9.787266e-4
GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation	9.887858e-4
GO:0002883	regulation of hypersensitivity	9.961096e-4
GO:0048592	eye morphogenesis	9.975973e-4
GO:0031659	positive regulation of cyclin-dependent protein kinase activity involved in G1/S	1.019346e-3
GO:0072012	glomerulus vasculature development	1.023599e-3
GO:0010922	positive regulation of phosphatase activity	1.023599e-3
GO:0032410	negative regulation of transporter activity	1.023599e-3
GO:0045348	positive regulation of MHC class II biosynthetic process	1.045320e-3
GO:0032847	regulation of cellular pH reduction	1.045320e-3
GO:0021555	midbrain-hindbrain boundary morphogenesis	1.058103e-3
GO:0007064	mitotic sister chromatid cohesion	1.058103e-3
GO:0021516	dorsal spinal cord development	1.061229e-3
GO:0030219	megakaryocyte differentiation	1.080994e-3
GO:0002885	positive regulation of hypersensitivity	1.080994e-3
GO:0018022	peptidyl-lysine methylation	1.080994e-3
GO:0048333	mesodermal cell differentiation	1.099843e-3
GO:0043067	regulation of programmed cell death	1.103967e-3
GO:0007498	mesoderm development	1.130540e-3
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.156328e-3
GO:0014874	response to stimulus involved in regulation of muscle adaptation	1.156328e-3
GO:0003218	cardiac left ventricle formation	1.174361e-3
GO:0002031	G-protein coupled receptor internalization	1.174361e-3
GO:0060021	palate development	1.176904e-3
GO:0016070	RNA metabolic process	1.178622e-3
GO:0060051	negative regulation of protein glycosylation	1.184424e-3
GO:0021629	olfactory nerve structural organization	1.184424e-3
GO:0003130	BMP signaling pathway involved in heart induction	1.184424e-3
GO:0010957	negative regulation of vitamin D biosynthetic process	1.184424e-3
GO:0019543	propionate catabolic process	1.184424e-3
GO:0002700	regulation of production of molecular mediator of immune response	1.195009e-3
GO:0010454	negative regulation of cell fate commitment	1.198489e-3
GO:0009225	nucleotide-sugar metabolic process	1.216104e-3
GO:0071310	cellular response to organic substance	1.232691e-3
GO:0000052	citrulline metabolic process	1.248816e-3
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	1.265422e-3
GO:0061004	pattern specification involved in kidney development	1.265545e-3
GO:0045662	negative regulation of myoblast differentiation	1.287428e-3
GO:0002315	marginal zone B cell differentiation	1.294892e-3
GO:0045661	regulation of myoblast differentiation	1.319453e-3
GO:0060592	mammary gland formation	1.336922e-3
GO:0010921	regulation of phosphatase activity	1.343181e-3
GO:0019477	L-lysine catabolic process	1.352075e-3
GO:0021670	lateral ventricle development	1.356123e-3
GO:0060921	sinoatrial node cell differentiation	1.393206e-3
GO:2000679	positive regulation of transcription regulatory region DNA binding	1.412820e-3
GO:0071900	regulation of protein serine/threonine kinase activity	1.415802e-3
GO:0032689	negative regulation of interferon-gamma production	1.438628e-3
GO:0000238	zygotene	1.445026e-3
GO:0060379	cardiac muscle cell myoblast differentiation	1.445026e-3
GO:0051054	positive regulation of DNA metabolic process	1.454525e-3
GO:0042981	regulation of apoptosis	1.457324e-3
GO:0070243	regulation of thymocyte apoptosis	1.469582e-3
GO:0060019	radial glial cell differentiation	1.474766e-3
GO:0002825	regulation of T-helper 1 type immune response	1.474766e-3
GO:0032481	positive regulation of type I interferon production	1.508128e-3
GO:0005978	glycogen biosynthetic process	1.509687e-3
GO:0043010	camera-type eye development	1.509696e-3
GO:0065004	protein-DNA complex assembly	1.552841e-3
GO:0045919	positive regulation of cytolysis	1.553934e-3
GO:0042414	epinephrine metabolic process	1.553934e-3
GO:0006550	isoleucine catabolic process	1.553934e-3