Novel motif:120

name:	motif120_TTSMTGNNGKTG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0043170	macromolecule metabolic process	1.813791e-18
GO:0044260	cellular macromolecule metabolic process	5.788883e-18
GO:2000273	positive regulation of receptor activity	4.407449e-15
GO:0051592	response to calcium ion	1.182516e-14
GO:0009611	response to wounding	3.422717e-14
GO:0042060	wound healing	1.725544e-13
GO:0010468	regulation of gene expression	2.072448e-13
GO:0060255	regulation of macromolecule metabolic process	8.004429e-13
GO:0006355	regulation of transcription, DNA-dependent	1.175070e-12
GO:0030154	cell differentiation	1.331449e-12
GO:0009888	tissue development	2.065154e-12
GO:0019222	regulation of metabolic process	2.290253e-12
GO:0090304	nucleic acid metabolic process	3.747487e-12
GO:0051252	regulation of RNA metabolic process	6.109873e-12
GO:0032501	multicellular organismal process	9.154435e-12
GO:2000112	regulation of cellular macromolecule biosynthetic process	1.022293e-11
GO:0010038	response to metal ion	1.129535e-11
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	1.141219e-11
GO:0071850	mitotic cell cycle arrest	1.172357e-11
GO:0016070	RNA metabolic process	1.228084e-11
GO:0009653	anatomical structure morphogenesis	1.808474e-11
GO:0032502	developmental process	2.306251e-11
GO:2000467	positive regulation of glycogen (starch) synthase activity	3.153189e-11
GO:0048869	cellular developmental process	3.291018e-11
GO:0006139	nucleobase-containing compound metabolic process	3.631614e-11
GO:0050896	response to stimulus	5.102553e-11
GO:0048646	anatomical structure formation involved in morphogenesis	5.951404e-11
GO:0050680	negative regulation of epithelial cell proliferation	7.688369e-11
GO:0010556	regulation of macromolecule biosynthetic process	8.041224e-11
GO:2000465	regulation of glycogen (starch) synthase activity	8.919429e-11
GO:0006351	transcription, DNA-dependent	1.059070e-10
GO:0001775	cell activation	1.184193e-10
GO:0050794	regulation of cellular process	1.423669e-10
GO:0030261	chromosome condensation	1.662183e-10
GO:0080090	regulation of primary metabolic process	2.239777e-10
GO:0032774	RNA biosynthetic process	2.683831e-10
GO:0009887	organ morphogenesis	3.405320e-10
GO:0002694	regulation of leukocyte activation	5.217203e-10
GO:0051276	chromosome organization	5.367046e-10
GO:0044238	primary metabolic process	5.686929e-10
GO:0010467	gene expression	5.861032e-10
GO:0019219	regulation of nucleobase-containing compound metabolic process	6.696759e-10
GO:0009889	regulation of biosynthetic process	7.358589e-10
GO:0031326	regulation of cellular biosynthetic process	7.678766e-10
GO:0034645	cellular macromolecule biosynthetic process	8.576411e-10
GO:0050789	regulation of biological process	1.009736e-9
GO:0030241	skeletal muscle myosin thick filament assembly	1.394065e-9
GO:0006950	response to stress	1.421609e-9
GO:0043085	positive regulation of catalytic activity	1.568671e-9
GO:0050863	regulation of T cell activation	1.886173e-9
GO:0051171	regulation of nitrogen compound metabolic process	1.932847e-9
GO:0065007	biological regulation	1.986300e-9
GO:0051146	striated muscle cell differentiation	2.203148e-9
GO:0048583	regulation of response to stimulus	2.795707e-9
GO:0009059	macromolecule biosynthetic process	4.100593e-9
GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine	4.418352e-9
GO:0008152	metabolic process	4.568968e-9
GO:0030855	epithelial cell differentiation	5.563869e-9
GO:0006807	nitrogen compound metabolic process	7.094026e-9
GO:0030168	platelet activation	7.502986e-9
GO:0050790	regulation of catalytic activity	8.507050e-9
GO:0031323	regulation of cellular metabolic process	8.805401e-9
GO:0034641	cellular nitrogen compound metabolic process	9.110951e-9
GO:0008285	negative regulation of cell proliferation	1.192748e-8
GO:0006349	regulation of gene expression by genetic imprinting	1.420880e-8
GO:0046628	positive regulation of insulin receptor signaling pathway	1.608340e-8
GO:0006323	DNA packaging	1.670908e-8
GO:0018149	peptide cross-linking	1.728078e-8
GO:0048739	cardiac muscle fiber development	2.523326e-8
GO:0050865	regulation of cell activation	2.648605e-8
GO:0071103	DNA conformation change	2.652395e-8
GO:0044237	cellular metabolic process	3.156920e-8
GO:0019538	protein metabolic process	3.288622e-8
GO:0002576	platelet degranulation	3.402814e-8
GO:0044093	positive regulation of molecular function	3.443220e-8
GO:0007275	multicellular organismal development	4.045735e-8
GO:0051249	regulation of lymphocyte activation	4.536533e-8
GO:0042986	positive regulation of amyloid precursor protein biosynthetic process	4.822153e-8
GO:0009968	negative regulation of signal transduction	4.843801e-8
GO:0042127	regulation of cell proliferation	4.965349e-8
GO:0006955	immune response	4.984643e-8
GO:0023057	negative regulation of signaling	5.188650e-8
GO:0008544	epidermis development	5.227067e-8
GO:0010648	negative regulation of cell communication	5.897794e-8
GO:0002696	positive regulation of leukocyte activation	6.650688e-8
GO:0050678	regulation of epithelial cell proliferation	7.731689e-8
GO:0007015	actin filament organization	8.639755e-8
GO:0018199	peptidyl-glutamine modification	1.018013e-7
GO:0060662	salivary gland cavitation	1.025172e-7
GO:0007389	pattern specification process	1.044854e-7
GO:0046006	regulation of activated T cell proliferation	1.060514e-7
GO:0065009	regulation of molecular function	1.070046e-7
GO:0002376	immune system process	1.111904e-7
GO:0048731	system development	1.159068e-7
GO:0060370	susceptibility to T cell mediated cytotoxicity	1.499764e-7
GO:0048769	sarcomerogenesis	2.029782e-7
GO:0071577	zinc ion transmembrane transport	2.537250e-7
GO:0002250	adaptive immune response	2.557188e-7
GO:0050867	positive regulation of cell activation	2.831788e-7
GO:0050870	positive regulation of T cell activation	3.016052e-7
GO:0010035	response to inorganic substance	3.261129e-7
GO:0060429	epithelium development	3.852551e-7
GO:0048584	positive regulation of response to stimulus	4.074393e-7
GO:0055013	cardiac muscle cell development	4.130767e-7
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	4.503752e-7
GO:0007162	negative regulation of cell adhesion	4.567003e-7
GO:0014866	skeletal myofibril assembly	4.615112e-7
GO:0071514	genetic imprinting	4.778339e-7
GO:0009966	regulation of signal transduction	4.999098e-7
GO:0007596	blood coagulation	5.498602e-7
GO:0043163	cell envelope organization	5.653929e-7
GO:0034621	cellular macromolecular complex subunit organization	5.729723e-7
GO:0055001	muscle cell development	5.752362e-7
GO:0045214	sarcomere organization	5.867605e-7
GO:2000627	positive regulation of miRNA catabolic process	6.095261e-7
GO:0071042	nuclear polyadenylation-dependent mRNA catabolic process	6.095261e-7
GO:0000964	mitochondrial RNA 5'-end processing	6.095261e-7
GO:0002765	immune response-inhibiting signal transduction	7.277695e-7
GO:0043412	macromolecule modification	7.499430e-7
GO:0051251	positive regulation of lymphocyte activation	8.327614e-7
GO:0007599	hemostasis	8.487235e-7
GO:0016043	cellular component organization	8.782670e-7
GO:0044267	cellular protein metabolic process	8.804811e-7
GO:0006464	protein modification process	8.928177e-7
GO:0030216	keratinocyte differentiation	9.024494e-7
GO:0002682	regulation of immune system process	1.013538e-6
GO:0032119	sequestering of zinc ion	1.123268e-6
GO:0009698	phenylpropanoid metabolic process	1.147001e-6
GO:0016568	chromatin modification	1.178648e-6
GO:0045859	regulation of protein kinase activity	1.184574e-6
GO:0007398	ectoderm development	1.238696e-6
GO:0048856	anatomical structure development	1.364875e-6
GO:0051131	chaperone-mediated protein complex assembly	1.555186e-6
GO:0005513	detection of calcium ion	1.717412e-6
GO:0071840	cellular component organization or biogenesis	1.723807e-6
GO:0003002	regionalization	1.909084e-6
GO:0051338	regulation of transferase activity	1.984026e-6
GO:0007166	cell surface receptor linked signaling pathway	2.088843e-6
GO:0090031	positive regulation of steroid hormone biosynthetic process	2.260452e-6
GO:0030239	myofibril assembly	2.292985e-6
GO:0043633	polyadenylation-dependent RNA catabolic process	2.485815e-6
GO:0048468	cell development	2.501301e-6
GO:0021796	cerebral cortex regionalization	2.568367e-6
GO:0071842	cellular component organization at cellular level	2.762078e-6
GO:0042104	positive regulation of activated T cell proliferation	2.905781e-6
GO:0016310	phosphorylation	2.954052e-6
GO:0048513	organ development	3.105446e-6
GO:0008219	cell death	3.272733e-6
GO:0042692	muscle cell differentiation	3.296520e-6
GO:0007076	mitotic chromosome condensation	3.663255e-6
GO:0042094	interleukin-2 biosynthetic process	3.770821e-6
GO:0001818	negative regulation of cytokine production	3.820450e-6
GO:0030240	skeletal muscle thin filament assembly	3.896741e-6
GO:0048522	positive regulation of cellular process	3.960909e-6
GO:0034605	cellular response to heat	3.963691e-6
GO:0006887	exocytosis	3.970379e-6
GO:0031032	actomyosin structure organization	3.975199e-6
GO:0045918	negative regulation of cytolysis	4.013996e-6
GO:0002684	positive regulation of immune system process	4.173482e-6
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	4.358974e-6
GO:0051893	regulation of focal adhesion assembly	4.370787e-6
GO:0048730	epidermis morphogenesis	4.449274e-6
GO:0009812	flavonoid metabolic process	4.949835e-6
GO:0043623	cellular protein complex assembly	5.256692e-6
GO:0031424	keratinization	5.458235e-6
GO:0010646	regulation of cell communication	5.461792e-6
GO:0034622	cellular macromolecular complex assembly	5.889840e-6
GO:0033059	cellular pigmentation	5.998877e-6
GO:0055003	cardiac myofibril assembly	6.129073e-6
GO:0043933	macromolecular complex subunit organization	6.129607e-6
GO:0055002	striated muscle cell development	6.335140e-6
GO:0008284	positive regulation of cell proliferation	6.403551e-6
GO:0017158	regulation of calcium ion-dependent exocytosis	6.438974e-6
GO:0006796	phosphate-containing compound metabolic process	6.551880e-6
GO:0016265	death	6.713289e-6
GO:0010759	positive regulation of macrophage chemotaxis	6.755489e-6
GO:0009913	epidermal cell differentiation	6.775771e-6
GO:0070875	positive regulation of glycogen metabolic process	7.053755e-6
GO:0090030	regulation of steroid hormone biosynthetic process	7.269040e-6
GO:0030007	cellular potassium ion homeostasis	7.396334e-6
GO:0051336	regulation of hydrolase activity	7.504822e-6
GO:0019748	secondary metabolic process	7.915983e-6
GO:0065003	macromolecular complex assembly	8.207749e-6
GO:0050878	regulation of body fluid levels	9.136739e-6
GO:0031295	T cell costimulation	9.269124e-6
GO:0043473	pigmentation	9.822429e-6
GO:0030382	sperm mitochondrion organization	9.910607e-6
GO:0010692	regulation of alkaline phosphatase activity	9.996206e-6
GO:0010628	positive regulation of gene expression	1.004604e-5
GO:0071841	cellular component organization or biogenesis at cellular level	1.056632e-5
GO:0000965	mitochondrial RNA 3'-end processing	1.087151e-5
GO:0000958	mitochondrial mRNA catabolic process	1.087151e-5
GO:0000962	positive regulation of mitochondrial RNA catabolic process	1.087151e-5
GO:0090343	positive regulation of cell aging	1.098258e-5
GO:0009987	cellular process	1.135460e-5
GO:0001649	osteoblast differentiation	1.263696e-5
GO:0048523	negative regulation of cellular process	1.394022e-5
GO:0023051	regulation of signaling	1.408323e-5
GO:0009115	xanthine catabolic process	1.414012e-5
GO:0007422	peripheral nervous system development	1.493280e-5
GO:0046110	xanthine metabolic process	1.560970e-5
GO:0050860	negative regulation of T cell receptor signaling pathway	1.623674e-5
GO:0002449	lymphocyte mediated immunity	1.628626e-5
GO:0002769	natural killer cell inhibitory signaling pathway	1.703874e-5
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	1.733846e-5
GO:0046889	positive regulation of lipid biosynthetic process	1.783347e-5
GO:0010758	regulation of macrophage chemotaxis	1.821949e-5
GO:0006325	chromatin organization	1.901295e-5
GO:0010812	negative regulation of cell-substrate adhesion	1.927312e-5
GO:0043549	regulation of kinase activity	1.942141e-5
GO:0048518	positive regulation of biological process	1.964682e-5
GO:0045741	positive regulation of epidermal growth factor-activated receptor activity	1.979324e-5
GO:0051241	negative regulation of multicellular organismal process	2.024486e-5
GO:0006357	regulation of transcription from RNA polymerase II promoter	2.330384e-5
GO:0009593	detection of chemical stimulus	2.349702e-5
GO:0022407	regulation of cell-cell adhesion	2.485789e-5
GO:0045940	positive regulation of steroid metabolic process	2.604015e-5
GO:0006468	protein phosphorylation	2.699060e-5
GO:0009443	pyridoxal 5'-phosphate salvage	2.716811e-5
GO:0051041	positive regulation of calcium-independent cell-cell adhesion	2.793565e-5
GO:0050902	leukocyte adhesive activation	2.793565e-5
GO:0019724	B cell mediated immunity	2.853185e-5
GO:0055069	zinc ion homeostasis	3.021072e-5
GO:0051482	elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger	3.089885e-5
GO:0035148	tube formation	3.179623e-5
GO:0070271	protein complex biogenesis	3.225064e-5
GO:0051648	vesicle localization	3.253544e-5
GO:0006434	seryl-tRNA aminoacylation	3.265227e-5
GO:0001501	skeletal system development	3.439367e-5
GO:0071675	regulation of mononuclear cell migration	3.492873e-5
GO:0032717	negative regulation of interleukin-8 production	3.605877e-5
GO:0071822	protein complex subunit organization	3.684192e-5
GO:0007165	signal transduction	3.719257e-5
GO:0043277	apoptotic cell clearance	3.827827e-5
GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development	3.886518e-5
GO:0048747	muscle fiber development	3.902343e-5
GO:0001574	ganglioside biosynthetic process	3.927722e-5
GO:0007154	cell communication	3.947279e-5
GO:0006461	protein complex assembly	3.955802e-5
GO:0071902	positive regulation of protein serine/threonine kinase activity	4.083072e-5
GO:0040011	locomotion	4.176313e-5
GO:0009058	biosynthetic process	4.180647e-5
GO:0001932	regulation of protein phosphorylation	4.321144e-5
GO:0021918	regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment	4.572509e-5
GO:0021905	forebrain-midbrain boundary formation	4.572509e-5
GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	4.572509e-5
GO:0003322	pancreatic A cell development	4.572509e-5
GO:0032940	secretion by cell	4.732577e-5
GO:0044249	cellular biosynthetic process	5.149503e-5
GO:0071622	regulation of granulocyte chemotaxis	5.591431e-5
GO:0002891	positive regulation of immunoglobulin mediated immune response	5.658961e-5
GO:0051973	positive regulation of telomerase activity	5.832815e-5
GO:0050983	deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase	5.898666e-5
GO:0006941	striated muscle contraction	6.001768e-5
GO:0006928	cellular component movement	6.087582e-5
GO:0045725	positive regulation of glycogen biosynthetic process	6.403342e-5
GO:0051345	positive regulation of hydrolase activity	6.490507e-5
GO:0060675	ureteric bud morphogenesis	6.559298e-5
GO:0072592	oxygen metabolic process	7.013552e-5
GO:0001935	endothelial cell proliferation	7.134188e-5
GO:0019220	regulation of phosphate metabolic process	7.137303e-5
GO:0046580	negative regulation of Ras protein signal transduction	7.359626e-5
GO:0016064	immunoglobulin mediated immune response	7.576529e-5
GO:0009952	anterior/posterior pattern specification	7.701983e-5
GO:0006710	androgen catabolic process	7.702665e-5
GO:0051347	positive regulation of transferase activity	7.720996e-5
GO:0030183	B cell differentiation	7.947203e-5
GO:0035282	segmentation	8.126570e-5
GO:0030155	regulation of cell adhesion	8.143026e-5
GO:0043616	keratinocyte proliferation	8.250510e-5
GO:0042221	response to chemical stimulus	8.437067e-5
GO:0035051	cardiac cell differentiation	8.437640e-5
GO:0031017	exocrine pancreas development	8.452913e-5
GO:0008016	regulation of heart contraction	8.490014e-5
GO:0045760	positive regulation of action potential	8.650177e-5
GO:0010557	positive regulation of macromolecule biosynthetic process	8.957253e-5
GO:0048066	developmental pigmentation	9.007615e-5
GO:0043589	skin morphogenesis	9.226498e-5
GO:0006956	complement activation	9.326005e-5
GO:0072009	nephron epithelium development	9.401984e-5
GO:0045860	positive regulation of protein kinase activity	9.952045e-5
GO:0071954	chemokine (C-C motif) ligand 11 production	1.002832e-4
GO:2000525	positive regulation of T cell costimulation	1.002832e-4
GO:0002215	defense response to nematode	1.002832e-4
GO:0035712	T-helper 2 cell activation	1.002832e-4
GO:0035709	memory T cell activation	1.002832e-4
GO:0035708	interleukin-4-dependent isotype switching to IgE isotypes	1.002832e-4
GO:0006338	chromatin remodeling	1.033738e-4
GO:0042325	regulation of phosphorylation	1.047565e-4
GO:0008154	actin polymerization or depolymerization	1.048377e-4
GO:0048729	tissue morphogenesis	1.053652e-4
GO:0042113	B cell activation	1.079504e-4
GO:0048598	embryonic morphogenesis	1.085358e-4
GO:0042984	regulation of amyloid precursor protein biosynthetic process	1.120758e-4
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	1.141809e-4
GO:0046415	urate metabolic process	1.165319e-4
GO:0050912	detection of chemical stimulus involved in sensory perception of taste	1.178569e-4
GO:0008286	insulin receptor signaling pathway	1.249678e-4
GO:0000959	mitochondrial RNA metabolic process	1.272223e-4
GO:0008283	cell proliferation	1.287189e-4
GO:0006888	ER to Golgi vesicle-mediated transport	1.291688e-4
GO:0071636	positive regulation of transforming growth factor beta production	1.292749e-4
GO:0016192	vesicle-mediated transport	1.313917e-4
GO:0071899	negative regulation of estrogen receptor binding	1.334514e-4
GO:0010694	positive regulation of alkaline phosphatase activity	1.375559e-4
GO:0006882	cellular zinc ion homeostasis	1.389785e-4
GO:0006688	glycosphingolipid biosynthetic process	1.399136e-4
GO:0023052	signaling	1.440356e-4
GO:0010647	positive regulation of cell communication	1.476505e-4
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	1.502333e-4
GO:0048519	negative regulation of biological process	1.524134e-4
GO:0006996	organelle organization	1.526224e-4
GO:0006333	chromatin assembly or disassembly	1.542288e-4
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	1.643080e-4
GO:0061333	renal tubule morphogenesis	1.664665e-4
GO:0000966	RNA 5'-end processing	1.669390e-4
GO:0010927	cellular component assembly involved in morphogenesis	1.748392e-4
GO:2000116	regulation of cysteine-type endopeptidase activity	1.751903e-4
GO:0045893	positive regulation of transcription, DNA-dependent	1.790834e-4
GO:0035986	senescence-associated heterochromatin focus formation	1.801770e-4
GO:2000774	positive regulation of cellular senescence	1.801770e-4
GO:0042129	regulation of T cell proliferation	1.809876e-4
GO:0006954	inflammatory response	1.837311e-4
GO:0009891	positive regulation of biosynthetic process	1.871140e-4
GO:0009624	response to nematode	1.877482e-4
GO:0046814	virion attachment, binding of host cell surface coreceptor	1.877482e-4
GO:0007200	activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger	1.901880e-4
GO:0030198	extracellular matrix organization	1.929995e-4
GO:0072283	metanephric renal vesicle morphogenesis	1.942186e-4
GO:0002052	positive regulation of neuroblast proliferation	1.949224e-4
GO:0051058	negative regulation of small GTPase mediated signal transduction	1.978950e-4
GO:0090084	negative regulation of inclusion body assembly	2.024792e-4
GO:0051216	cartilage development	2.101933e-4
GO:0007249	I-kappaB kinase/NF-kappaB cascade	2.103063e-4
GO:0051254	positive regulation of RNA metabolic process	2.155203e-4
GO:0048016	inositol phosphate-mediated signaling	2.244197e-4
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	2.291102e-4
GO:0048193	Golgi vesicle transport	2.301600e-4
GO:0072088	nephron epithelium morphogenesis	2.353027e-4
GO:0002252	immune effector process	2.357885e-4
GO:0032914	positive regulation of transforming growth factor beta1 production	2.373733e-4
GO:0012501	programmed cell death	2.382493e-4
GO:0045329	carnitine biosynthetic process	2.429336e-4
GO:0048102	autophagic cell death	2.432305e-4
GO:0031328	positive regulation of cellular biosynthetic process	2.440272e-4
GO:0023056	positive regulation of signaling	2.511669e-4
GO:0033148	positive regulation of estrogen receptor signaling pathway	2.593616e-4
GO:0071845	cellular component disassembly at cellular level	2.595683e-4
GO:0051302	regulation of cell division	2.607922e-4
GO:0045794	negative regulation of cell volume	2.619937e-4
GO:0072073	kidney epithelium development	2.670789e-4
GO:0045945	positive regulation of transcription from RNA polymerase III promoter	2.752357e-4
GO:0045726	positive regulation of integrin biosynthetic process	2.790414e-4
GO:0051856	adhesion to symbiont	2.818295e-4
GO:0019062	virion attachment to host cell surface receptor	2.836370e-4
GO:0060209	estrus	2.869843e-4
GO:0006952	defense response	2.949338e-4
GO:0008291	acetylcholine metabolic process	2.971114e-4
GO:0090183	regulation of kidney development	2.974594e-4
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	2.989406e-4
GO:0060816	random inactivation of X chromosome	2.989869e-4
GO:0006427	histidyl-tRNA aminoacylation	2.989869e-4
GO:0006959	humoral immune response	3.008527e-4
GO:0000070	mitotic sister chromatid segregation	3.025414e-4
GO:0009893	positive regulation of metabolic process	3.066535e-4
GO:0022411	cellular component disassembly	3.113744e-4
GO:0009967	positive regulation of signal transduction	3.114384e-4
GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway	3.126569e-4
GO:0032438	melanosome organization	3.132985e-4
GO:0016571	histone methylation	3.149377e-4
GO:0008380	RNA splicing	3.193649e-4
GO:0048753	pigment granule organization	3.210981e-4
GO:0000819	sister chromatid segregation	3.272540e-4
GO:0033572	transferrin transport	3.288701e-4
GO:0032653	regulation of interleukin-10 production	3.355172e-4
GO:0002712	regulation of B cell mediated immunity	3.376085e-4
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	3.430838e-4
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	3.486459e-4
GO:0032733	positive regulation of interleukin-10 production	3.597664e-4
GO:0050798	activated T cell proliferation	3.615527e-4
GO:0046885	regulation of hormone biosynthetic process	3.635759e-4
GO:0006120	mitochondrial electron transport, NADH to ubiquinone	3.664680e-4
GO:0000398	nuclear mRNA splicing, via spliceosome	3.672696e-4
GO:0022607	cellular component assembly	3.727837e-4
GO:0035625	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway	3.766488e-4
GO:0031069	hair follicle morphogenesis	3.862228e-4
GO:0001756	somitogenesis	3.880109e-4
GO:0032203	telomere formation via telomerase	3.944926e-4
GO:0032350	regulation of hormone metabolic process	3.960274e-4
GO:0070997	neuron death	4.051111e-4
GO:0030317	sperm motility	4.091482e-4
GO:0010604	positive regulation of macromolecule metabolic process	4.111901e-4
GO:0001985	negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure	4.183782e-4
GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	4.196133e-4
GO:0048793	pronephros development	4.203420e-4
GO:0035456	response to interferon-beta	4.245348e-4
GO:0051716	cellular response to stimulus	4.322754e-4
GO:0001658	branching involved in ureteric bud morphogenesis	4.359144e-4
GO:0045822	negative regulation of heart contraction	4.615742e-4
GO:0002064	epithelial cell development	4.640608e-4
GO:0051972	regulation of telomerase activity	4.692314e-4
GO:0043154	negative regulation of caspase activity	4.841644e-4
GO:0016071	mRNA metabolic process	4.852386e-4
GO:0048935	peripheral nervous system neuron development	4.944915e-4
GO:0042363	fat-soluble vitamin catabolic process	4.978822e-4
GO:0061072	iris morphogenesis	5.003626e-4
GO:0006958	complement activation, classical pathway	5.014859e-4
GO:0070584	mitochondrion morphogenesis	5.042145e-4
GO:0006337	nucleosome disassembly	5.089755e-4
GO:0019064	viral envelope fusion with host membrane	5.092200e-4
GO:0045823	positive regulation of heart contraction	5.092736e-4
GO:0043408	regulation of MAPKKK cascade	5.095516e-4
GO:0050778	positive regulation of immune response	5.110536e-4
GO:0006259	DNA metabolic process	5.166678e-4
GO:0033151	V(D)J recombination	5.225053e-4
GO:0022409	positive regulation of cell-cell adhesion	5.239004e-4
GO:0050856	regulation of T cell receptor signaling pathway	5.240783e-4
GO:0006428	isoleucyl-tRNA aminoacylation	5.255018e-4
GO:0072553	terminal button organization	5.273530e-4
GO:0046587	positive regulation of calcium-dependent cell-cell adhesion	5.273530e-4
GO:0003057	regulation of the force of heart contraction by chemical signal	5.332209e-4
GO:0070873	regulation of glycogen metabolic process	5.336105e-4
GO:0032400	melanosome localization	5.386753e-4
GO:0051546	keratinocyte migration	5.417125e-4
GO:0045906	negative regulation of vasoconstriction	5.444441e-4
GO:0001952	regulation of cell-matrix adhesion	5.539628e-4
GO:0055007	cardiac muscle cell differentiation	5.541919e-4
GO:0045892	negative regulation of transcription, DNA-dependent	5.673438e-4
GO:0007411	axon guidance	5.704795e-4
GO:0031399	regulation of protein modification process	5.706168e-4
GO:0048706	embryonic skeletal system development	5.738707e-4
GO:2000027	regulation of organ morphogenesis	5.762133e-4
GO:0021535	cell migration in hindbrain	5.769338e-4
GO:0042823	pyridoxal phosphate biosynthetic process	5.932445e-4
GO:0021935	cerebellar granule cell precursor tangential migration	5.932445e-4
GO:0050868	negative regulation of T cell activation	6.140046e-4
GO:0072087	renal vesicle development	6.141277e-4
GO:0034465	response to carbon monoxide	6.144286e-4
GO:0072028	nephron morphogenesis	6.222229e-4
GO:0010558	negative regulation of macromolecule biosynthetic process	6.308111e-4
GO:0072079	nephron tubule formation	6.329463e-4
GO:0001101	response to acid	6.449139e-4
GO:0032623	interleukin-2 production	6.484962e-4
GO:0006620	posttranslational protein targeting to membrane	6.644793e-4
GO:0032714	negative regulation of interleukin-5 production	6.734701e-4
GO:0060073	micturition	6.850622e-4
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	6.921502e-4
GO:0000375	RNA splicing, via transesterification reactions	6.974527e-4
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	6.993908e-4
GO:0034378	chylomicron assembly	7.067546e-4
GO:0050909	sensory perception of taste	7.106317e-4
GO:0051923	sulfation	7.108481e-4
GO:0046586	regulation of calcium-dependent cell-cell adhesion	7.225791e-4
GO:0010560	positive regulation of glycoprotein biosynthetic process	7.245596e-4
GO:0046651	lymphocyte proliferation	7.260334e-4
GO:0051402	neuron apoptosis	7.302811e-4
GO:0045087	innate immune response	7.358265e-4
GO:0060710	chorio-allantoic fusion	7.512947e-4
GO:0005975	carbohydrate metabolic process	7.591077e-4
GO:0007499	ectoderm and mesoderm interaction	7.787472e-4
GO:0002200	somatic diversification of immune receptors	7.787886e-4
GO:0002455	humoral immune response mediated by circulating immunoglobulin	7.858192e-4
GO:0060628	regulation of ER to Golgi vesicle-mediated transport	7.925949e-4
GO:0061326	renal tubule development	8.021821e-4
GO:0060252	positive regulation of glial cell proliferation	8.116718e-4
GO:0010827	regulation of glucose transport	8.232947e-4
GO:0048070	regulation of developmental pigmentation	8.264526e-4
GO:0033674	positive regulation of kinase activity	8.268042e-4
GO:0023019	signal transduction involved in regulation of gene expression	8.307476e-4
GO:0009408	response to heat	8.480900e-4
GO:0000117	regulation of transcription involved in G2/M-phase of mitotic cell cycle	8.552684e-4
GO:0001525	angiogenesis	8.611981e-4
GO:0072080	nephron tubule development	8.617570e-4
GO:0050877	neurological system process	8.702022e-4
GO:0045333	cellular respiration	8.755983e-4
GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	8.810604e-4
GO:0032570	response to progesterone stimulus	8.849808e-4
GO:0002285	lymphocyte activation involved in immune response	8.859253e-4
GO:0021797	forebrain anterior/posterior pattern specification	9.083271e-4
GO:0032696	negative regulation of interleukin-13 production	9.247257e-4
GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	9.395638e-4
GO:0006284	base-excision repair	9.458110e-4
GO:0010627	regulation of intracellular protein kinase cascade	9.547389e-4
GO:0010810	regulation of cell-substrate adhesion	9.566261e-4
GO:0051875	pigment granule localization	9.566628e-4
GO:0072077	renal vesicle morphogenesis	9.633797e-4
GO:0048705	skeletal system morphogenesis	9.652428e-4
GO:0050954	sensory perception of mechanical stimulus	9.761864e-4
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	9.770381e-4
GO:2000026	regulation of multicellular organismal development	9.787981e-4
GO:0019932	second-messenger-mediated signaling	9.859418e-4
GO:0048520	positive regulation of behavior	9.981304e-4
GO:0042107	cytokine metabolic process	1.005648e-3
GO:0070373	negative regulation of ERK1 and ERK2 cascade	1.006155e-3
GO:0019985	translesion synthesis	1.009498e-3
GO:0032703	negative regulation of interleukin-2 production	1.014715e-3
GO:0002889	regulation of immunoglobulin mediated immune response	1.029304e-3
GO:0006583	melanin biosynthetic process from tyrosine	1.029817e-3
GO:0031497	chromatin assembly	1.034718e-3
GO:0043032	positive regulation of macrophage activation	1.042867e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0050896	response to stimulus	1.370961e-13
GO:0032501	multicellular organismal process	6.612518e-13
GO:0050789	regulation of biological process	8.668838e-11
GO:0065007	biological regulation	2.507686e-10
GO:0006950	response to stress	5.677509e-10
GO:0019222	regulation of metabolic process	7.115861e-10
GO:2000774	positive regulation of cellular senescence	1.667571e-9
GO:0090402	oncogene-induced senescence	1.667571e-9
GO:0035986	senescence-associated heterochromatin focus formation	1.667571e-9
GO:0051234	establishment of localization	1.689720e-9
GO:0051179	localization	1.949050e-9
GO:0050794	regulation of cellular process	2.142358e-9
GO:0001878	response to yeast	3.313714e-9
GO:0002456	T cell mediated immunity	4.823568e-9
GO:0051591	response to cAMP	5.139371e-9
GO:0009605	response to external stimulus	8.576659e-9
GO:0006810	transport	9.311438e-9
GO:0001887	selenium compound metabolic process	9.963270e-9
GO:0070588	calcium ion transmembrane transport	1.025191e-8
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	1.081815e-8
GO:0007154	cell communication	1.098720e-8
GO:0032649	regulation of interferon-gamma production	1.636321e-8
GO:0048193	Golgi vesicle transport	1.667086e-8
GO:0031507	heterochromatin formation	1.685844e-8
GO:0051716	cellular response to stimulus	1.954414e-8
GO:0046649	lymphocyte activation	2.048921e-8
GO:0001775	cell activation	2.322577e-8
GO:0060255	regulation of macromolecule metabolic process	2.412403e-8
GO:0051561	elevation of mitochondrial calcium ion concentration	2.470525e-8
GO:0040018	positive regulation of multicellular organism growth	2.911145e-8
GO:0051239	regulation of multicellular organismal process	3.497060e-8
GO:0048705	skeletal system morphogenesis	4.120051e-8
GO:0021758	putamen development	4.282180e-8
GO:0021757	caudate nucleus development	4.282180e-8
GO:0080090	regulation of primary metabolic process	4.288632e-8
GO:0051592	response to calcium ion	4.514828e-8
GO:0031214	biomineral tissue development	4.739664e-8
GO:0031324	negative regulation of cellular metabolic process	4.963869e-8
GO:0002376	immune system process	4.967347e-8
GO:0048519	negative regulation of biological process	5.483910e-8
GO:0010605	negative regulation of macromolecule metabolic process	5.840747e-8
GO:0006952	defense response	6.740594e-8
GO:0042221	response to chemical stimulus	7.134583e-8
GO:0009892	negative regulation of metabolic process	7.375499e-8
GO:0009612	response to mechanical stimulus	8.239493e-8
GO:0007275	multicellular organismal development	8.617533e-8
GO:0009890	negative regulation of biosynthetic process	1.086379e-7
GO:0045321	leukocyte activation	1.143587e-7
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	1.146500e-7
GO:0006811	ion transport	1.172157e-7
GO:0050790	regulation of catalytic activity	1.247920e-7
GO:0012502	induction of programmed cell death	1.384520e-7
GO:0008283	cell proliferation	1.397229e-7
GO:0006917	induction of apoptosis	1.444354e-7
GO:0023052	signaling	1.499672e-7
GO:2000772	regulation of cellular senescence	1.561998e-7
GO:0032469	endoplasmic reticulum calcium ion homeostasis	1.983623e-7
GO:0072183	negative regulation of nephron tubule epithelial cell differentiation	2.021040e-7
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	2.049395e-7
GO:0043933	macromolecular complex subunit organization	2.114884e-7
GO:0031327	negative regulation of cellular biosynthetic process	2.124166e-7
GO:0050900	leukocyte migration	2.159049e-7
GO:0031133	regulation of axon diameter	2.600209e-7
GO:0072182	regulation of nephron tubule epithelial cell differentiation	2.648606e-7
GO:0051253	negative regulation of RNA metabolic process	2.993792e-7
GO:0032502	developmental process	3.076894e-7
GO:0018149	peptide cross-linking	3.144443e-7
GO:0007165	signal transduction	3.427618e-7
GO:0010558	negative regulation of macromolecule biosynthetic process	3.447370e-7
GO:0002439	chronic inflammatory response to antigenic stimulus	3.737743e-7
GO:0065008	regulation of biological quality	3.805604e-7
GO:0060557	positive regulation of vitamin D biosynthetic process	3.833706e-7
GO:0008152	metabolic process	4.024278e-7
GO:0031323	regulation of cellular metabolic process	4.226279e-7
GO:0009620	response to fungus	4.308428e-7
GO:0043269	regulation of ion transport	5.185344e-7
GO:0065009	regulation of molecular function	5.232231e-7
GO:0002149	hypochlorous acid biosynthetic process	5.941202e-7
GO:0048706	embryonic skeletal system development	5.958195e-7
GO:0090343	positive regulation of cell aging	6.218438e-7
GO:0045892	negative regulation of transcription, DNA-dependent	6.470691e-7
GO:0042297	vocal learning	6.886100e-7
GO:0042110	T cell activation	7.791954e-7
GO:0030264	nuclear fragmentation involved in apoptotic nuclear change	7.949910e-7
GO:0009914	hormone transport	8.565816e-7
GO:0060986	endocrine hormone secretion	9.159562e-7
GO:0032963	collagen metabolic process	9.410029e-7
GO:2000679	positive regulation of transcription regulatory region DNA binding	9.570328e-7
GO:0060558	regulation of calcidiol 1-monooxygenase activity	1.036417e-6
GO:0043085	positive regulation of catalytic activity	1.087897e-6
GO:0006816	calcium ion transport	1.120263e-6
GO:0070509	calcium ion import	1.235173e-6
GO:0051172	negative regulation of nitrogen compound metabolic process	1.343506e-6
GO:0007600	sensory perception	1.512540e-6
GO:0009611	response to wounding	1.528115e-6
GO:0043170	macromolecule metabolic process	1.596015e-6
GO:0034341	response to interferon-gamma	1.619664e-6
GO:0008625	induction of apoptosis via death domain receptors	1.831232e-6
GO:0048731	system development	1.861524e-6
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	1.971764e-6
GO:0006919	activation of caspase activity	2.131787e-6
GO:0002679	respiratory burst involved in defense response	2.140736e-6
GO:0070206	protein trimerization	2.152843e-6
GO:0048732	gland development	2.158244e-6
GO:0051707	response to other organism	2.218440e-6
GO:0031448	positive regulation of fast-twitch skeletal muscle fiber contraction	2.333240e-6
GO:0030098	lymphocyte differentiation	2.462271e-6
GO:0010035	response to inorganic substance	2.488416e-6
GO:0051241	negative regulation of multicellular organismal process	2.564421e-6
GO:0032536	regulation of cell projection size	2.619943e-6
GO:0006066	alcohol metabolic process	2.665852e-6
GO:0060013	righting reflex	2.774410e-6
GO:0044259	multicellular organismal macromolecule metabolic process	2.883109e-6
GO:0001935	endothelial cell proliferation	2.937164e-6
GO:0034220	ion transmembrane transport	3.048029e-6
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.382457e-6
GO:2000683	regulation of cellular response to X-ray	3.695818e-6
GO:0070838	divalent metal ion transport	3.721031e-6
GO:0065003	macromolecular complex assembly	3.781346e-6
GO:0072511	divalent inorganic cation transport	3.823552e-6
GO:0072208	metanephric smooth muscle tissue development	3.972254e-6
GO:0090094	metanephric cap mesenchymal cell proliferation involved in metanephros development	3.972254e-6
GO:0072259	metanephric interstitial cell development	3.972254e-6
GO:0072184	renal vesicle progenitor cell differentiation	3.972254e-6
GO:0072169	specification of posterior mesonephric tubule identity	3.972254e-6
GO:0072168	specification of anterior mesonephric tubule identity	3.972254e-6
GO:0051353	positive regulation of oxidoreductase activity	4.352813e-6
GO:0048856	anatomical structure development	4.756057e-6
GO:0032689	negative regulation of interferon-gamma production	4.867697e-6
GO:0048583	regulation of response to stimulus	5.034027e-6
GO:0045884	regulation of survival gene product expression	5.045262e-6
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	5.061018e-6
GO:0002740	negative regulation of cytokine secretion involved in immune response	5.061018e-6
GO:0051259	protein oligomerization	5.241492e-6
GO:0001503	ossification	5.464142e-6
GO:0048523	negative regulation of cellular process	5.947895e-6
GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	6.027250e-6
GO:0045682	regulation of epidermis development	6.215995e-6
GO:0051704	multi-organism process	6.260308e-6
GO:0090076	relaxation of skeletal muscle	6.290354e-6
GO:0032470	elevation of endoplasmic reticulum calcium ion concentration	6.290354e-6
GO:0016310	phosphorylation	6.440599e-6
GO:0044093	positive regulation of molecular function	6.500537e-6
GO:2000696	regulation of epithelial cell differentiation involved in kidney development	6.593790e-6
GO:0001706	endoderm formation	7.821290e-6
GO:0030879	mammary gland development	9.021812e-6
GO:0002739	regulation of cytokine secretion involved in immune response	9.222937e-6
GO:0030490	maturation of SSU-rRNA	9.273761e-6
GO:0048878	chemical homeostasis	9.641782e-6
GO:0046879	hormone secretion	9.681064e-6
GO:0003008	system process	9.775142e-6
GO:0045730	respiratory burst	1.116281e-5
GO:0060556	regulation of vitamin D biosynthetic process	1.127574e-5
GO:0051171	regulation of nitrogen compound metabolic process	1.154767e-5
GO:0031117	positive regulation of microtubule depolymerization	1.162066e-5
GO:0009628	response to abiotic stimulus	1.167195e-5
GO:0045351	type I interferon biosynthetic process	1.210540e-5
GO:0009786	regulation of asymmetric cell division	1.224993e-5
GO:0048704	embryonic skeletal system morphogenesis	1.243585e-5
GO:0046666	retinal cell programmed cell death	1.250842e-5
GO:0050877	neurological system process	1.305992e-5
GO:0022037	metencephalon development	1.351073e-5
GO:0001501	skeletal system development	1.357168e-5
GO:0045994	positive regulation of translational initiation by iron	1.410197e-5
GO:0061048	negative regulation of branching involved in lung morphogenesis	1.410197e-5
GO:0034116	positive regulation of heterotypic cell-cell adhesion	1.410197e-5
GO:0002037	negative regulation of L-glutamate transport	1.410197e-5
GO:0023051	regulation of signaling	1.423475e-5
GO:0034369	plasma lipoprotein particle remodeling	1.430684e-5
GO:0008637	apoptotic mitochondrial changes	1.466633e-5
GO:0051797	regulation of hair follicle development	1.471608e-5
GO:0050707	regulation of cytokine secretion	1.512091e-5
GO:0010629	negative regulation of gene expression	1.530527e-5
GO:0021549	cerebellum development	1.542372e-5
GO:0016043	cellular component organization	1.547266e-5
GO:0009607	response to biotic stimulus	1.552729e-5
GO:0002904	positive regulation of B cell apoptosis	1.578672e-5
GO:0001553	luteinization	1.626091e-5
GO:0034382	chylomicron remnant clearance	1.642187e-5
GO:0010646	regulation of cell communication	1.660295e-5
GO:0031346	positive regulation of cell projection organization	1.686539e-5
GO:0046544	development of secondary male sexual characteristics	1.726454e-5
GO:0070059	apoptosis in response to endoplasmic reticulum stress	1.790697e-5
GO:0001101	response to acid	1.902799e-5
GO:0009888	tissue development	1.956075e-5
GO:0032369	negative regulation of lipid transport	1.974439e-5
GO:0071840	cellular component organization or biogenesis	2.091084e-5
GO:0072178	nephric duct morphogenesis	2.151206e-5
GO:0072176	nephric duct development	2.156967e-5
GO:0010038	response to metal ion	2.188404e-5
GO:0034375	high-density lipoprotein particle remodeling	2.196520e-5
GO:0006915	apoptosis	2.260177e-5
GO:0045429	positive regulation of nitric oxide biosynthetic process	2.287900e-5
GO:0070508	cholesterol import	2.388572e-5
GO:0021521	ventral spinal cord interneuron specification	2.458553e-5
GO:0048333	mesodermal cell differentiation	2.476510e-5
GO:0010985	negative regulation of lipoprotein particle clearance	2.478118e-5
GO:0006954	inflammatory response	2.562984e-5
GO:0019219	regulation of nucleobase-containing compound metabolic process	2.741654e-5
GO:0060052	neurofilament cytoskeleton organization	2.779682e-5
GO:0008624	induction of apoptosis by extracellular signals	2.894544e-5
GO:0072503	cellular divalent inorganic cation homeostasis	2.923478e-5
GO:0044236	multicellular organismal metabolic process	2.947535e-5
GO:0006812	cation transport	2.972928e-5
GO:0044260	cellular macromolecule metabolic process	3.120923e-5
GO:0048699	generation of neurons	3.166785e-5
GO:0022612	gland morphogenesis	3.200397e-5
GO:0042592	homeostatic process	3.202435e-5
GO:0060579	ventral spinal cord interneuron fate commitment	3.213778e-5
GO:0050715	positive regulation of cytokine secretion	3.334342e-5
GO:0002367	cytokine production involved in immune response	3.441120e-5
GO:0031344	regulation of cell projection organization	3.467736e-5
GO:0010975	regulation of neuron projection development	3.579377e-5
GO:0009887	organ morphogenesis	3.795666e-5
GO:0007143	female meiosis	3.805168e-5
GO:0042634	regulation of hair cycle	3.814339e-5
GO:2000026	regulation of multicellular organismal development	3.960684e-5
GO:0031223	auditory behavior	4.008353e-5
GO:0043200	response to amino acid stimulus	4.111602e-5
GO:0001818	negative regulation of cytokine production	4.153017e-5
GO:0032703	negative regulation of interleukin-2 production	4.184929e-5
GO:0051094	positive regulation of developmental process	4.317271e-5
GO:0030001	metal ion transport	4.351258e-5
GO:0009059	macromolecule biosynthetic process	4.434512e-5
GO:0050953	sensory perception of light stimulus	4.843986e-5
GO:0030730	sequestering of triglyceride	5.017759e-5
GO:0000028	ribosomal small subunit assembly	5.311435e-5
GO:0030003	cellular cation homeostasis	5.386701e-5
GO:0051336	regulation of hydrolase activity	5.561172e-5
GO:0042476	odontogenesis	5.680588e-5
GO:0045684	positive regulation of epidermis development	5.718793e-5
GO:0014819	regulation of skeletal muscle contraction	5.870012e-5
GO:0051252	regulation of RNA metabolic process	5.989634e-5
GO:0007601	visual perception	6.032139e-5
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	6.043624e-5
GO:0030856	regulation of epithelial cell differentiation	6.121459e-5
GO:0010033	response to organic substance	6.158027e-5
GO:0009790	embryo development	6.337175e-5
GO:0050974	detection of mechanical stimulus involved in sensory perception	6.554273e-5
GO:0042743	hydrogen peroxide metabolic process	6.589863e-5
GO:0002544	chronic inflammatory response	6.649617e-5
GO:0050954	sensory perception of mechanical stimulus	6.765917e-5
GO:0002521	leukocyte differentiation	6.784078e-5
GO:0048771	tissue remodeling	6.834678e-5
GO:0021514	ventral spinal cord interneuron differentiation	6.899284e-5
GO:0051276	chromosome organization	7.059213e-5
GO:0006796	phosphate-containing compound metabolic process	7.091986e-5
GO:0035786	protein complex oligomerization	7.112493e-5
GO:0045080	positive regulation of chemokine biosynthetic process	7.240455e-5
GO:0010468	regulation of gene expression	7.297955e-5
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	7.790935e-5
GO:0050673	epithelial cell proliferation	8.042421e-5
GO:0032375	negative regulation of cholesterol transport	8.995845e-5
GO:0012501	programmed cell death	9.122932e-5
GO:0045885	positive regulation of survival gene product expression	9.158969e-5
GO:0019538	protein metabolic process	9.195393e-5
GO:0002369	T cell cytokine production	9.248683e-5
GO:0044238	primary metabolic process	9.345828e-5
GO:0006874	cellular calcium ion homeostasis	9.416245e-5
GO:2000116	regulation of cysteine-type endopeptidase activity	9.434277e-5
GO:0051606	detection of stimulus	9.461135e-5
GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	9.535968e-5
GO:0031960	response to corticosteroid stimulus	9.553531e-5
GO:0048518	positive regulation of biological process	9.901150e-5
GO:0042255	ribosome assembly	1.008683e-4
GO:0045814	negative regulation of gene expression, epigenetic	1.010029e-4
GO:0048483	autonomic nervous system development	1.014363e-4
GO:0016525	negative regulation of angiogenesis	1.044667e-4
GO:0043009	chordate embryonic development	1.084334e-4
GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	1.094989e-4
GO:0051345	positive regulation of hydrolase activity	1.096214e-4
GO:0033135	regulation of peptidyl-serine phosphorylation	1.115349e-4
GO:0052547	regulation of peptidase activity	1.124388e-4
GO:0032274	gonadotropin secretion	1.134566e-4
GO:0072593	reactive oxygen species metabolic process	1.135417e-4
GO:0018958	phenol-containing compound metabolic process	1.139227e-4
GO:0051856	adhesion to symbiont	1.140018e-4
GO:0032606	type I interferon production	1.140018e-4
GO:0048522	positive regulation of cellular process	1.177964e-4
GO:0060555	induction of necroptosis by extracellular signals	1.180311e-4
GO:2000611	positive regulation of thyroid hormone generation	1.180311e-4
GO:0034380	high-density lipoprotein particle assembly	1.180345e-4
GO:0040011	locomotion	1.185455e-4
GO:0050821	protein stabilization	1.191934e-4
GO:0060443	mammary gland morphogenesis	1.196036e-4
GO:0050793	regulation of developmental process	1.203151e-4
GO:0032879	regulation of localization	1.211398e-4
GO:0042981	regulation of apoptosis	1.216157e-4
GO:0043280	positive regulation of caspase activity	1.250619e-4
GO:0045113	regulation of integrin biosynthetic process	1.255181e-4
GO:0021575	hindbrain morphogenesis	1.259352e-4
GO:0021587	cerebellum morphogenesis	1.263748e-4
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.266828e-4
GO:0032774	RNA biosynthetic process	1.278337e-4
GO:0042273	ribosomal large subunit biogenesis	1.295725e-4
GO:0060056	mammary gland involution	1.301746e-4
GO:0023057	negative regulation of signaling	1.303978e-4
GO:0014074	response to purine-containing compound	1.323993e-4
GO:0050832	defense response to fungus	1.334351e-4
GO:0051291	protein heterooligomerization	1.345778e-4
GO:0070271	protein complex biogenesis	1.347082e-4
GO:0052548	regulation of endopeptidase activity	1.369057e-4
GO:0060021	palate development	1.370804e-4
GO:0006351	transcription, DNA-dependent	1.374757e-4
GO:0034505	tooth mineralization	1.396337e-4
GO:0007267	cell-cell signaling	1.442927e-4
GO:0060346	bone trabecula formation	1.454797e-4
GO:0034645	cellular macromolecule biosynthetic process	1.508261e-4
GO:0055080	cation homeostasis	1.546395e-4
GO:0033138	positive regulation of peptidyl-serine phosphorylation	1.561585e-4
GO:0001777	T cell homeostatic proliferation	1.577252e-4
GO:0060992	response to fungicide	1.587543e-4
GO:0006338	chromatin remodeling	1.593419e-4
GO:0072162	metanephric mesenchymal cell differentiation	1.610501e-4
GO:0040007	growth	1.626432e-4
GO:0009966	regulation of signal transduction	1.635361e-4
GO:0080135	regulation of cellular response to stress	1.659284e-4
GO:0021554	optic nerve development	1.701904e-4
GO:0006461	protein complex assembly	1.718470e-4
GO:0034605	cellular response to heat	1.743269e-4
GO:0006801	superoxide metabolic process	1.747683e-4
GO:0031647	regulation of protein stability	1.759025e-4
GO:0010648	negative regulation of cell communication	1.779784e-4
GO:0043066	negative regulation of apoptosis	1.837160e-4
GO:0006468	protein phosphorylation	1.853642e-4
GO:0051385	response to mineralocorticoid stimulus	1.932188e-4
GO:0009581	detection of external stimulus	1.935611e-4
GO:0009792	embryo development ending in birth or egg hatching	1.939724e-4
GO:0072177	mesonephric duct development	1.983698e-4
GO:0010922	positive regulation of phosphatase activity	1.993348e-4
GO:0022008	neurogenesis	2.004419e-4
GO:0006885	regulation of pH	2.032242e-4
GO:0072180	mesonephric duct morphogenesis	2.085434e-4
GO:0042113	B cell activation	2.085561e-4
GO:0002036	regulation of L-glutamate transport	2.130248e-4
GO:0007000	nucleolus organization	2.147877e-4
GO:0010984	regulation of lipoprotein particle clearance	2.150002e-4
GO:0010694	positive regulation of alkaline phosphatase activity	2.150002e-4
GO:0007638	mechanosensory behavior	2.150002e-4
GO:0072507	divalent inorganic cation homeostasis	2.158479e-4
GO:0009889	regulation of biosynthetic process	2.181086e-4
GO:0043484	regulation of RNA splicing	2.205983e-4
GO:0015680	intracellular copper ion transport	2.245921e-4
GO:0042274	ribosomal small subunit biogenesis	2.269042e-4
GO:0003006	developmental process involved in reproduction	2.282631e-4
GO:0001958	endochondral ossification	2.285558e-4
GO:0071822	protein complex subunit organization	2.334355e-4
GO:0051005	negative regulation of lipoprotein lipase activity	2.371728e-4
GO:0043243	positive regulation of protein complex disassembly	2.406293e-4
GO:0048745	smooth muscle tissue development	2.452461e-4
GO:0050776	regulation of immune response	2.501262e-4
GO:0048513	organ development	2.512851e-4
GO:0009653	anatomical structure morphogenesis	2.527929e-4
GO:0051049	regulation of transport	2.542075e-4
GO:0071346	cellular response to interferon-gamma	2.548284e-4
GO:0031670	cellular response to nutrient	2.569821e-4
GO:0072143	mesangial cell development	2.591913e-4
GO:0032770	positive regulation of monooxygenase activity	2.595285e-4
GO:0010812	negative regulation of cell-substrate adhesion	2.601314e-4
GO:0007162	negative regulation of cell adhesion	2.628290e-4
GO:0010942	positive regulation of cell death	2.647148e-4
GO:0043067	regulation of programmed cell death	2.682188e-4
GO:0023061	signal release	2.683314e-4
GO:0051412	response to corticosterone stimulus	2.707195e-4
GO:0032674	regulation of interleukin-5 production	2.718245e-4
GO:0030574	collagen catabolic process	2.718245e-4
GO:0071397	cellular response to cholesterol	2.743725e-4
GO:0016192	vesicle-mediated transport	2.745247e-4
GO:0006323	DNA packaging	2.770137e-4
GO:0045989	positive regulation of striated muscle contraction	2.794803e-4
GO:0002572	pro-T cell differentiation	2.803110e-4
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.803110e-4
GO:0071827	plasma lipoprotein particle organization	2.808676e-4
GO:0010817	regulation of hormone levels	2.839128e-4
GO:0051130	positive regulation of cellular component organization	2.868639e-4
GO:0071295	cellular response to vitamin	2.905774e-4
GO:0042701	progesterone secretion	2.925843e-4
GO:0007605	sensory perception of sound	2.988358e-4
GO:0001817	regulation of cytokine production	2.995983e-4
GO:0015876	acetyl-CoA transport	3.011798e-4
GO:0042843	D-xylose catabolic process	3.011798e-4
GO:0048539	bone marrow development	3.034630e-4
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.034630e-4
GO:0042461	photoreceptor cell development	3.035952e-4
GO:0002437	inflammatory response to antigenic stimulus	3.054672e-4
GO:0042403	thyroid hormone metabolic process	3.081211e-4
GO:0090107	regulation of high-density lipoprotein particle assembly	3.101698e-4
GO:0048291	isotype switching to IgG isotypes	3.101698e-4
GO:0002368	B cell cytokine production	3.101698e-4
GO:0090342	regulation of cell aging	3.165419e-4
GO:0045595	regulation of cell differentiation	3.217543e-4
GO:0031326	regulation of cellular biosynthetic process	3.225667e-4
GO:0051204	protein insertion into mitochondrial membrane	3.240192e-4
GO:0006851	mitochondrial calcium ion transport	3.282623e-4
GO:0001555	oocyte growth	3.282623e-4
GO:0046449	creatinine metabolic process	3.287144e-4
GO:0055067	monovalent inorganic cation homeostasis	3.293404e-4
GO:0051004	regulation of lipoprotein lipase activity	3.430365e-4
GO:0042537	benzene-containing compound metabolic process	3.454947e-4
GO:0007160	cell-matrix adhesion	3.455866e-4
GO:0002874	regulation of chronic inflammatory response to antigenic stimulus	3.457137e-4
GO:0014012	peripheral nervous system axon regeneration	3.516394e-4
GO:0002252	immune effector process	3.526189e-4
GO:0051138	positive regulation of NK T cell differentiation	3.550829e-4
GO:0070265	necrotic cell death	3.558043e-4
GO:0043622	cortical microtubule organization	3.579918e-4
GO:0045358	negative regulation of interferon-beta biosynthetic process	3.579918e-4
GO:0030103	vasopressin secretion	3.579918e-4
GO:0007231	osmosensory signaling pathway	3.579918e-4
GO:0002694	regulation of leukocyte activation	3.625916e-4
GO:0050995	negative regulation of lipid catabolic process	3.683439e-4
GO:0000302	response to reactive oxygen species	3.702092e-4
GO:0021513	spinal cord dorsal/ventral patterning	3.710726e-4
GO:0032094	response to food	3.719286e-4
GO:0006955	immune response	3.805474e-4
GO:0043525	positive regulation of neuron apoptosis	3.818825e-4
GO:0009058	biosynthetic process	3.822658e-4
GO:0032673	regulation of interleukin-4 production	3.893238e-4
GO:0003179	heart valve morphogenesis	3.944172e-4
GO:0006325	chromatin organization	4.005246e-4
GO:0060004	reflex	4.012875e-4
GO:0030217	T cell differentiation	4.025744e-4
GO:0043069	negative regulation of programmed cell death	4.061668e-4
GO:0006355	regulation of transcription, DNA-dependent	4.096522e-4
GO:0051240	positive regulation of multicellular organismal process	4.118392e-4
GO:0045428	regulation of nitric oxide biosynthetic process	4.121877e-4
GO:0033687	osteoblast proliferation	4.182608e-4
GO:0010720	positive regulation of cell development	4.199314e-4
GO:0042462	eye photoreceptor cell development	4.203575e-4
GO:0007369	gastrulation	4.213953e-4
GO:0046661	male sex differentiation	4.295495e-4
GO:2000677	regulation of transcription regulatory region DNA binding	4.297065e-4
GO:0072202	cell differentiation involved in metanephros development	4.307233e-4
GO:0050982	detection of mechanical stimulus	4.346681e-4
GO:0009968	negative regulation of signal transduction	4.419244e-4
GO:0042098	T cell proliferation	4.422128e-4
GO:0000003	reproduction	4.515019e-4
GO:0010940	positive regulation of necrotic cell death	4.588867e-4
GO:0015698	inorganic anion transport	4.615794e-4
GO:0022603	regulation of anatomical structure morphogenesis	4.770669e-4
GO:0006875	cellular metal ion homeostasis	4.815514e-4
GO:0006464	protein modification process	4.820061e-4
GO:0009987	cellular process	4.879415e-4
GO:0030183	B cell differentiation	4.895411e-4
GO:0070887	cellular response to chemical stimulus	4.934379e-4
GO:0002634	regulation of germinal center formation	4.946739e-4
GO:0055074	calcium ion homeostasis	4.982767e-4
GO:0045109	intermediate filament organization	5.030922e-4
GO:0032753	positive regulation of interleukin-4 production	5.084245e-4
GO:0050851	antigen receptor-mediated signaling pathway	5.138266e-4
GO:0060675	ureteric bud morphogenesis	5.187471e-4
GO:2000667	positive regulation of interleukin-13 secretion	5.226467e-4
GO:0001806	type IV hypersensitivity	5.226467e-4
GO:2000734	negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation	5.226467e-4
GO:2000664	positive regulation of interleukin-5 secretion	5.226467e-4
GO:2000703	negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation	5.226467e-4
GO:0010897	negative regulation of triglyceride catabolic process	5.226467e-4
GO:2000607	negative regulation of cell proliferation involved in mesonephros development	5.226467e-4
GO:0010987	negative regulation of high-density lipoprotein particle clearance	5.226467e-4
GO:0060374	mast cell differentiation	5.226467e-4
GO:0010941	regulation of cell death	5.339104e-4
GO:0045104	intermediate filament cytoskeleton organization	5.415219e-4
GO:0055082	cellular chemical homeostasis	5.446547e-4
GO:0032964	collagen biosynthetic process	5.463338e-4
GO:0001823	mesonephros development	5.474880e-4
GO:0001844	protein insertion into mitochondrial membrane involved in induction of apoptosis	5.505284e-4
GO:0060620	regulation of cholesterol import	5.527917e-4
GO:0070302	regulation of stress-activated protein kinase signaling cascade	5.534056e-4
GO:0021523	somatic motor neuron differentiation	5.606959e-4
GO:0030154	cell differentiation	5.655536e-4
GO:0006921	cellular component disassembly involved in apoptosis	5.677575e-4
GO:0031650	regulation of heat generation	5.678817e-4
GO:0007268	synaptic transmission	5.789249e-4
GO:0016477	cell migration	5.821774e-4
GO:0043901	negative regulation of multi-organism process	5.857383e-4
GO:0007548	sex differentiation	5.981777e-4
GO:0031000	response to caffeine	6.016470e-4
GO:0002757	immune response-activating signal transduction	6.092785e-4
GO:0032863	activation of Rac GTPase activity	6.152271e-4
GO:0048541	Peyer's patch development	6.153391e-4
GO:0000187	activation of MAPK activity	6.273100e-4
GO:0060284	regulation of cell development	6.304175e-4
GO:0048584	positive regulation of response to stimulus	6.397566e-4
GO:0051251	positive regulation of lymphocyte activation	6.438880e-4
GO:0016568	chromatin modification	6.446444e-4
GO:0050850	positive regulation of calcium-mediated signaling	6.512956e-4
GO:0006576	cellular biogenic amine metabolic process	6.570324e-4
GO:0050865	regulation of cell activation	6.620721e-4
GO:0034337	RNA folding	6.794771e-4
GO:0042035	regulation of cytokine biosynthetic process	6.795866e-4
GO:0050801	ion homeostasis	6.810202e-4
GO:0043065	positive regulation of apoptosis	6.930110e-4
GO:0019233	sensory perception of pain	7.020045e-4
GO:0002764	immune response-regulating signaling pathway	7.096186e-4
GO:0042542	response to hydrogen peroxide	7.152523e-4
GO:0051325	interphase	7.240526e-4
GO:0030097	hemopoiesis	7.284073e-4
GO:0010556	regulation of macromolecule biosynthetic process	7.306036e-4
GO:0048608	reproductive structure development	7.339793e-4
GO:0009582	detection of abiotic stimulus	7.359135e-4