Novel motif:34

name:	motif34_GANCCT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0010624	regulation of Schwann cell proliferation	4.687878e-14
GO:0060251	regulation of glial cell proliferation	1.031219e-12
GO:0010625	positive regulation of Schwann cell proliferation	1.772459e-11
GO:0002019	regulation of renal output by angiotensin	1.328053e-10
GO:0002002	regulation of angiotensin levels in blood	6.294237e-10
GO:0060020	Bergmann glial cell differentiation	2.746715e-9
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	4.478233e-9
GO:0070208	protein heterotrimerization	5.391754e-9
GO:0031440	regulation of mRNA 3'-end processing	6.621242e-9
GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	9.886428e-9
GO:0008210	estrogen metabolic process	1.351774e-8
GO:0031442	positive regulation of mRNA 3'-end processing	1.613222e-8
GO:0032753	positive regulation of interleukin-4 production	3.297390e-8
GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	4.369866e-8
GO:0007386	compartment pattern specification	4.443614e-8
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	6.746011e-8
GO:0071874	cellular response to norepinephrine stimulus	8.817637e-8
GO:0060253	negative regulation of glial cell proliferation	9.580009e-8
GO:0016056	rhodopsin mediated signaling pathway	1.164353e-7
GO:0007296	vitellogenesis	1.539460e-7
GO:0060351	cartilage development involved in endochondral bone morphogenesis	1.765977e-7
GO:0060897	neural plate regionalization	2.361346e-7
GO:0046434	organophosphate catabolic process	3.958287e-7
GO:0051693	actin filament capping	4.016429e-7
GO:0007522	visceral muscle development	4.283529e-7
GO:0051898	negative regulation of protein kinase B signaling cascade	5.181932e-7
GO:0048570	notochord morphogenesis	6.328018e-7
GO:0060252	positive regulation of glial cell proliferation	6.402329e-7
GO:0032571	response to vitamin K	6.923444e-7
GO:0006012	galactose metabolic process	7.050499e-7
GO:0006689	ganglioside catabolic process	7.242092e-7
GO:0030509	BMP signaling pathway	7.531929e-7
GO:0034504	protein localization to nucleus	8.136142e-7
GO:0008078	mesodermal cell migration	1.029346e-6
GO:0021999	neural plate anterior/posterior regionalization	1.076551e-6
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	1.114007e-6
GO:0030037	actin filament reorganization involved in cell cycle	1.350217e-6
GO:0045606	positive regulation of epidermal cell differentiation	1.435471e-6
GO:0060448	dichotomous subdivision of terminal units involved in lung branching	1.675602e-6
GO:0032933	SREBP-mediated signaling pathway	1.715169e-6
GO:0035814	negative regulation of renal sodium excretion	1.787256e-6
GO:0071276	cellular response to cadmium ion	1.789287e-6
GO:0051580	regulation of neurotransmitter uptake	1.790050e-6
GO:0034505	tooth mineralization	2.259155e-6
GO:0060177	regulation of angiotensin metabolic process	2.407763e-6
GO:0003180	aortic valve morphogenesis	2.485944e-6
GO:0000072	M phase specific microtubule process	2.562631e-6
GO:0009313	oligosaccharide catabolic process	2.851884e-6
GO:0006545	glycine biosynthetic process	2.851884e-6
GO:0042396	phosphagen biosynthetic process	2.930881e-6
GO:0070574	cadmium ion transmembrane transport	3.305798e-6
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	3.548689e-6
GO:0007603	phototransduction, visible light	3.592523e-6
GO:0019532	oxalate transport	3.636729e-6
GO:0014028	notochord formation	3.762193e-6
GO:0042506	tyrosine phosphorylation of Stat5 protein	3.783727e-6
GO:0001990	regulation of systemic arterial blood pressure by hormone	3.836672e-6
GO:0045655	regulation of monocyte differentiation	3.993280e-6
GO:0060337	type I interferon-mediated signaling pathway	4.810508e-6
GO:0014807	regulation of somitogenesis	5.029560e-6
GO:0014014	negative regulation of gliogenesis	5.422701e-6
GO:0046314	phosphocreatine biosynthetic process	5.525175e-6
GO:0034340	response to type I interferon	5.583187e-6
GO:0002579	positive regulation of antigen processing and presentation	5.618087e-6
GO:0032462	regulation of protein homooligomerization	6.024923e-6
GO:0060326	cell chemotaxis	6.201750e-6
GO:0000413	protein peptidyl-prolyl isomerization	6.695472e-6
GO:0030835	negative regulation of actin filament depolymerization	6.762181e-6
GO:0045838	positive regulation of membrane potential	7.155942e-6
GO:0060586	multicellular organismal iron ion homeostasis	8.785680e-6
GO:0032459	regulation of protein oligomerization	8.941301e-6
GO:0060323	head morphogenesis	9.130951e-6
GO:0014013	regulation of gliogenesis	1.030929e-5
GO:0002268	follicular dendritic cell differentiation	1.032475e-5
GO:0043462	regulation of ATPase activity	1.079008e-5
GO:0045657	positive regulation of monocyte differentiation	1.132421e-5
GO:0019265	glycine biosynthetic process, by transamination of glyoxylate	1.146712e-5
GO:0046724	oxalic acid secretion	1.146712e-5
GO:0045604	regulation of epidermal cell differentiation	1.152134e-5
GO:0042177	negative regulation of protein catabolic process	1.157231e-5
GO:0007509	mesoderm migration involved in gastrulation	1.162767e-5
GO:0060319	primitive erythrocyte differentiation	1.186734e-5
GO:0002575	basophil chemotaxis	1.186734e-5
GO:0043491	protein kinase B signaling cascade	1.221350e-5
GO:0014015	positive regulation of gliogenesis	1.266209e-5
GO:0001694	histamine biosynthetic process	1.294990e-5
GO:0045575	basophil activation	1.294990e-5
GO:0003416	endochondral bone growth	1.342691e-5
GO:0007602	phototransduction	1.388220e-5
GO:0032526	response to retinoic acid	1.481400e-5
GO:0002407	dendritic cell chemotaxis	1.483568e-5
GO:0045415	negative regulation of interleukin-8 biosynthetic process	1.504922e-5
GO:0009651	response to salt stress	1.631992e-5
GO:0071421	manganese ion transmembrane transport	1.790818e-5
GO:0071104	response to interleukin-9	1.807228e-5
GO:0045619	regulation of lymphocyte differentiation	1.865976e-5
GO:0060896	neural plate pattern specification	2.112925e-5
GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger	2.311285e-5
GO:0060291	long-term synaptic potentiation	2.364362e-5
GO:0015884	folic acid transport	2.434224e-5
GO:0070979	protein K11-linked ubiquitination	2.488200e-5
GO:0010626	negative regulation of Schwann cell proliferation	2.492346e-5
GO:0001823	mesonephros development	2.515400e-5
GO:0001569	patterning of blood vessels	2.543923e-5
GO:0045835	negative regulation of meiosis	2.604146e-5
GO:0061014	positive regulation of mRNA catabolic process	2.694596e-5
GO:0016188	synaptic vesicle maturation	2.717733e-5
GO:0045618	positive regulation of keratinocyte differentiation	2.727278e-5
GO:0045061	thymic T cell selection	2.741635e-5
GO:0046855	inositol phosphate dephosphorylation	2.755532e-5
GO:0018012	N-terminal peptidyl-alanine trimethylation	2.850655e-5
GO:0035572	N-terminal peptidyl-serine dimethylation	2.850655e-5
GO:0035573	N-terminal peptidyl-serine trimethylation	2.850655e-5
GO:0018016	N-terminal peptidyl-proline dimethylation	2.850655e-5
GO:0060730	regulation of intestinal epithelial structure maintenance	2.896112e-5
GO:0035305	negative regulation of dephosphorylation	3.083214e-5
GO:0003084	positive regulation of systemic arterial blood pressure	3.094939e-5
GO:0016142	O-glycoside catabolic process	3.190477e-5
GO:0006438	valyl-tRNA aminoacylation	3.241325e-5
GO:0031077	post-embryonic camera-type eye development	3.342543e-5
GO:0030903	notochord development	3.459943e-5
GO:0060346	bone trabecula formation	3.471441e-5
GO:0045668	negative regulation of osteoblast differentiation	3.473617e-5
GO:0010529	negative regulation of transposition	3.634596e-5
GO:0051016	barbed-end actin filament capping	3.891396e-5
GO:0035308	negative regulation of protein dephosphorylation	4.305470e-5
GO:0032515	negative regulation of phosphoprotein phosphatase activity	4.305470e-5
GO:0006544	glycine metabolic process	4.322133e-5
GO:0045060	negative thymic T cell selection	4.439465e-5
GO:0002026	regulation of the force of heart contraction	4.473106e-5
GO:0030834	regulation of actin filament depolymerization	4.495120e-5
GO:0060325	face morphogenesis	4.549466e-5
GO:0006695	cholesterol biosynthetic process	4.569763e-5
GO:0045414	regulation of interleukin-8 biosynthetic process	4.675830e-5
GO:0051365	cellular response to potassium ion starvation	4.793476e-5
GO:0014067	negative regulation of phosphatidylinositol 3-kinase cascade	4.975594e-5
GO:0002016	regulation of blood volume by renin-angiotensin	5.042500e-5
GO:0032863	activation of Rac GTPase activity	5.171137e-5
GO:0097150	neuronal stem cell maintenance	5.171137e-5
GO:0046847	filopodium assembly	5.219018e-5
GO:0042274	ribosomal small subunit biogenesis	5.268684e-5
GO:0007028	cytoplasm organization	5.304525e-5
GO:0051291	protein heterooligomerization	5.311983e-5
GO:0071545	inositol phosphate catabolic process	5.413221e-5
GO:0014896	muscle hypertrophy	5.442123e-5
GO:0006703	estrogen biosynthetic process	5.576976e-5
GO:0018894	dibenzo-p-dioxin metabolic process	5.576976e-5
GO:0009062	fatty acid catabolic process	5.613100e-5
GO:0045580	regulation of T cell differentiation	6.003279e-5
GO:0048242	epinephrine secretion	6.127432e-5
GO:0060456	positive regulation of digestive system process	6.384096e-5
GO:0032792	negative regulation of CREB transcription factor activity	6.580015e-5
GO:0001300	chronological cell aging	6.832017e-5
GO:0006690	icosanoid metabolic process	6.936347e-5
GO:0021773	striatal medium spiny neuron differentiation	7.040244e-5
GO:0009895	negative regulation of catabolic process	7.052751e-5
GO:0030322	stabilization of membrane potential	7.107178e-5
GO:0002438	acute inflammatory response to antigenic stimulus	7.107178e-5
GO:0060455	negative regulation of gastric acid secretion	7.254139e-5
GO:0002502	peptide antigen assembly with MHC class I protein complex	7.254139e-5
GO:0097118	neuroligin clustering	7.330355e-5
GO:0033085	negative regulation of T cell differentiation in thymus	7.428645e-5
GO:0043654	recognition of apoptotic cell	7.491732e-5
GO:0048569	post-embryonic organ development	7.609971e-5
GO:0008624	induction of apoptosis by extracellular signals	7.664965e-5
GO:0030035	microspike assembly	7.864172e-5
GO:0007263	nitric oxide mediated signal transduction	8.020075e-5
GO:0070206	protein trimerization	8.140003e-5
GO:0014895	smooth muscle hypertrophy	8.177385e-5
GO:0003106	negative regulation of glomerular filtration by angiotensin	8.177385e-5
GO:0010243	response to organic nitrogen	8.595703e-5
GO:0050685	positive regulation of mRNA processing	8.845700e-5
GO:0006635	fatty acid beta-oxidation	8.905728e-5
GO:0015862	uridine transport	8.948078e-5
GO:0009070	serine family amino acid biosynthetic process	9.264612e-5
GO:0048241	epinephrine transport	9.785613e-5
GO:0031295	T cell costimulation	9.999371e-5
GO:0035418	protein localization to synapse	1.004774e-4
GO:0097116	gephyrin clustering	1.023331e-4
GO:0034014	response to triglyceride	1.023331e-4
GO:0050862	positive regulation of T cell receptor signaling pathway	1.023331e-4
GO:0032673	regulation of interleukin-4 production	1.033511e-4
GO:0090189	regulation of branching involved in ureteric bud morphogenesis	1.038025e-4
GO:0046456	icosanoid biosynthetic process	1.051156e-4
GO:0002443	leukocyte mediated immunity	1.145470e-4
GO:0007021	tubulin complex assembly	1.162367e-4
GO:0018208	peptidyl-proline modification	1.172403e-4
GO:0002449	lymphocyte mediated immunity	1.174279e-4
GO:0050975	sensory perception of touch	1.198758e-4
GO:0002003	angiotensin maturation	1.203395e-4
GO:0097119	postsynaptic density protein 95 clustering	1.204181e-4
GO:0097104	postsynaptic membrane assembly	1.204181e-4
GO:0000076	DNA replication checkpoint	1.234658e-4
GO:0003229	ventricular cardiac muscle tissue development	1.282813e-4
GO:2000463	positive regulation of excitatory postsynaptic membrane potential	1.299238e-4
GO:0048844	artery morphogenesis	1.317584e-4
GO:0055010	ventricular cardiac muscle tissue morphogenesis	1.330665e-4
GO:0045651	positive regulation of macrophage differentiation	1.377520e-4
GO:0035105	sterol regulatory element binding protein import into nucleus	1.408575e-4
GO:0014874	response to stimulus involved in regulation of muscle adaptation	1.466357e-4
GO:0042074	cell migration involved in gastrulation	1.487664e-4
GO:0002250	adaptive immune response	1.518311e-4
GO:0016140	O-glycoside metabolic process	1.545128e-4
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	1.549522e-4
GO:0044057	regulation of system process	1.560231e-4
GO:0045079	negative regulation of chemokine biosynthetic process	1.599000e-4
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	1.615170e-4
GO:0035026	leading edge cell differentiation	1.686916e-4
GO:0072668	tubulin complex biogenesis	1.721272e-4
GO:0030149	sphingolipid catabolic process	1.893917e-4
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	1.950160e-4
GO:0050863	regulation of T cell activation	1.974308e-4
GO:0033159	negative regulation of protein import into nucleus, translocation	1.985884e-4
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	2.041834e-4
GO:0044062	regulation of excretion	2.090386e-4
GO:0002769	natural killer cell inhibitory signaling pathway	2.095895e-4
GO:0030513	positive regulation of BMP signaling pathway	2.142517e-4
GO:0051588	regulation of neurotransmitter transport	2.160898e-4
GO:0043088	regulation of Cdc42 GTPase activity	2.200945e-4
GO:0019221	cytokine-mediated signaling pathway	2.210320e-4
GO:0002883	regulation of hypersensitivity	2.211209e-4
GO:0033559	unsaturated fatty acid metabolic process	2.226050e-4
GO:0009133	nucleoside diphosphate biosynthetic process	2.273024e-4
GO:0060035	notochord cell development	2.338850e-4
GO:0045076	regulation of interleukin-2 biosynthetic process	2.352149e-4
GO:2000178	negative regulation of neural precursor cell proliferation	2.431357e-4
GO:0000088	mitotic prophase	2.459313e-4
GO:0010171	body morphogenesis	2.472151e-4
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	2.492031e-4
GO:0006026	aminoglycan catabolic process	2.522276e-4
GO:0002274	myeloid leukocyte activation	2.536287e-4
GO:0001817	regulation of cytokine production	2.540576e-4
GO:0048711	positive regulation of astrocyte differentiation	2.563636e-4
GO:0055009	atrial cardiac muscle tissue morphogenesis	2.581245e-4
GO:2000107	negative regulation of leukocyte apoptosis	2.587982e-4
GO:0006694	steroid biosynthetic process	2.657252e-4
GO:0009069	serine family amino acid metabolic process	2.660264e-4
GO:0048536	spleen development	2.664609e-4
GO:0042755	eating behavior	2.717765e-4
GO:0060343	trabecula formation	2.738179e-4
GO:0032862	activation of Rho GTPase activity	2.803495e-4
GO:0072125	negative regulation of glomerular mesangial cell proliferation	2.844962e-4
GO:2000001	regulation of DNA damage checkpoint	2.902161e-4
GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter	2.908455e-4
GO:0050870	positive regulation of T cell activation	2.926128e-4
GO:0002920	regulation of humoral immune response	2.930937e-4
GO:0001974	blood vessel remodeling	2.949636e-4
GO:0006782	protoporphyrinogen IX biosynthetic process	3.009873e-4
GO:0001941	postsynaptic membrane organization	3.013537e-4
GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	3.053615e-4
GO:0001757	somite specification	3.074188e-4
GO:0043471	regulation of cellular carbohydrate catabolic process	3.076878e-4
GO:0008065	establishment of blood-nerve barrier	3.327352e-4
GO:0002765	immune response-inhibiting signal transduction	3.327352e-4
GO:0032463	negative regulation of protein homooligomerization	3.355007e-4
GO:0002922	positive regulation of humoral immune response	3.363126e-4
GO:0072676	lymphocyte migration	3.399568e-4
GO:0050747	positive regulation of lipoprotein metabolic process	3.508765e-4
GO:0042886	amide transport	3.662063e-4
GO:0009583	detection of light stimulus	3.689745e-4
GO:0002005	angiotensin catabolic process in blood	3.765354e-4
GO:0070947	neutrophil mediated killing of fungus	3.765354e-4
GO:0006027	glycosaminoglycan catabolic process	3.808195e-4
GO:0051496	positive regulation of stress fiber assembly	3.826164e-4
GO:0051965	positive regulation of synapse assembly	3.828918e-4
GO:0010701	positive regulation of norepinephrine secretion	3.836976e-4
GO:0006636	unsaturated fatty acid biosynthetic process	3.864302e-4
GO:0007179	transforming growth factor beta receptor signaling pathway	3.882214e-4
GO:0046687	response to chromate	4.004272e-4
GO:0033986	response to methanol	4.004272e-4
GO:0042415	norepinephrine metabolic process	4.065658e-4
GO:0060236	regulation of mitotic spindle organization	4.128336e-4
GO:0032736	positive regulation of interleukin-13 production	4.135170e-4
GO:0009201	ribonucleoside triphosphate biosynthetic process	4.159508e-4
GO:0071356	cellular response to tumor necrosis factor	4.182813e-4
GO:0009635	response to herbicide	4.287311e-4
GO:0009151	purine deoxyribonucleotide metabolic process	4.330543e-4
GO:0060840	artery development	4.374437e-4
GO:0072178	nephric duct morphogenesis	4.421456e-4
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	4.494654e-4
GO:0061032	visceral serous pericardium development	4.494654e-4
GO:0014061	regulation of norepinephrine secretion	4.632015e-4
GO:0001807	regulation of type IV hypersensitivity	4.674165e-4
GO:0072166	posterior mesonephric tubule development	4.777679e-4
GO:0045058	T cell selection	4.841558e-4
GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	4.886427e-4
GO:0070383	DNA cytosine deamination	4.922686e-4
GO:2000251	positive regulation of actin cytoskeleton reorganization	4.922686e-4
GO:0042488	positive regulation of odontogenesis of dentine-containing tooth	4.922686e-4
GO:0060457	negative regulation of digestive system process	4.922686e-4
GO:0072333	signal transduction by p53 class mediator resulting in induction of anoikis	4.977424e-4
GO:0008612	peptidyl-lysine modification to hypusine	4.977424e-4
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	5.006014e-4
GO:0002830	positive regulation of type 2 immune response	5.035111e-4
GO:0010816	calcitonin catabolic process	5.035130e-4
GO:0034959	endothelin maturation	5.035130e-4
GO:0010814	substance P catabolic process	5.035130e-4
GO:0010508	positive regulation of autophagy	5.050966e-4
GO:0042339	keratan sulfate metabolic process	5.117358e-4
GO:0030423	targeting of mRNA for destruction involved in RNA interference	5.177487e-4
GO:0009258	10-formyltetrahydrofolate catabolic process	5.177487e-4
GO:0070715	sodium-dependent organic cation transport	5.201074e-4
GO:0060731	positive regulation of intestinal epithelial structure maintenance	5.201074e-4
GO:0052106	quorum sensing involved in interaction with host	5.201074e-4
GO:0043383	negative T cell selection	5.222144e-4
GO:0003073	regulation of systemic arterial blood pressure	5.244523e-4
GO:0045221	negative regulation of FasL biosynthetic process	5.371814e-4
GO:0002731	negative regulation of dendritic cell cytokine production	5.371814e-4
GO:0045086	positive regulation of interleukin-2 biosynthetic process	5.414173e-4
GO:0031952	regulation of protein autophosphorylation	5.750239e-4
GO:0010836	negative regulation of protein ADP-ribosylation	5.804646e-4
GO:0072176	nephric duct development	5.997245e-4
GO:0021919	BMP signaling pathway involved in spinal cord dorsal/ventral patterning	6.029220e-4
GO:0003105	negative regulation of glomerular filtration	6.029220e-4
GO:0006855	drug transmembrane transport	6.333147e-4
GO:0001768	establishment of T cell polarity	6.513597e-4
GO:0051929	positive regulation of calcium ion transport via voltage-gated calcium channel activity	6.513597e-4
GO:0043647	inositol phosphate metabolic process	6.518061e-4
GO:0018963	phthalate metabolic process	6.547418e-4
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	6.722549e-4
GO:0008625	induction of apoptosis via death domain receptors	7.000645e-4
GO:0009169	purine ribonucleoside monophosphate catabolic process	7.044293e-4
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	7.089205e-4
GO:0007221	positive regulation of transcription of Notch receptor target	7.114707e-4
GO:0048710	regulation of astrocyte differentiation	7.131083e-4
GO:0009142	nucleoside triphosphate biosynthetic process	7.154149e-4
GO:0045662	negative regulation of myoblast differentiation	7.386388e-4
GO:0003208	cardiac ventricle morphogenesis	7.497248e-4
GO:0001957	intramembranous ossification	7.528312e-4
GO:0015893	drug transport	7.548809e-4
GO:0050764	regulation of phagocytosis	7.561008e-4
GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion	7.778737e-4
GO:0061383	trabecula morphogenesis	7.789538e-4
GO:0045342	MHC class II biosynthetic process	7.881293e-4
GO:0070839	divalent metal ion export	7.881293e-4
GO:0043091	L-arginine import	7.881293e-4
GO:0032632	interleukin-3 production	7.881293e-4
GO:0006876	cellular cadmium ion homeostasis	7.881293e-4
GO:0015707	nitrite transport	7.881293e-4
GO:0001560	regulation of cell growth by extracellular stimulus	7.881293e-4
GO:0046466	membrane lipid catabolic process	7.900899e-4
GO:0016486	peptide hormone processing	8.065801e-4
GO:0006196	AMP catabolic process	8.079176e-4
GO:0019388	galactose catabolic process	8.079176e-4
GO:0018119	peptidyl-cysteine S-nitrosylation	8.079176e-4
GO:0032615	interleukin-12 production	8.203719e-4
GO:0060923	cardiac muscle cell fate commitment	8.260290e-4
GO:0097091	synaptic vesicle clustering	8.301824e-4
GO:0035854	eosinophil fate commitment	8.431759e-4
GO:0030222	eosinophil differentiation	8.431759e-4
GO:0071870	cellular response to catecholamine stimulus	8.435141e-4
GO:0009145	purine nucleoside triphosphate biosynthetic process	8.641315e-4
GO:0019322	pentose biosynthetic process	8.670707e-4
GO:0010940	positive regulation of necrotic cell death	8.684967e-4
GO:0003417	growth plate cartilage development	8.684967e-4
GO:0046655	folic acid metabolic process	8.728895e-4
GO:0010717	regulation of epithelial to mesenchymal transition	8.774317e-4
GO:0010954	positive regulation of protein processing	9.049051e-4
GO:0048661	positive regulation of smooth muscle cell proliferation	9.049321e-4
GO:0022616	DNA strand elongation	9.061580e-4
GO:0043101	purine-containing compound salvage	9.102360e-4
GO:0001808	negative regulation of type IV hypersensitivity	9.565136e-4
GO:0031104	dendrite regeneration	9.614687e-4
GO:0006607	NLS-bearing substrate import into nucleus	9.803916e-4
GO:0050821	protein stabilization	9.840523e-4
GO:0032653	regulation of interleukin-10 production	9.923980e-4
GO:0045582	positive regulation of T cell differentiation	1.008202e-3
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	1.026777e-3
GO:0021599	abducens nerve formation	1.029066e-3
GO:0051932	synaptic transmission, GABAergic	1.029066e-3
GO:0007634	optokinetic behavior	1.029066e-3
GO:2000210	positive regulation of anoikis	1.036638e-3
GO:0009132	nucleoside diphosphate metabolic process	1.046963e-3
GO:0044242	cellular lipid catabolic process	1.054767e-3
GO:0071071	regulation of phospholipid biosynthetic process	1.071070e-3
GO:0042593	glucose homeostasis	1.080993e-3
GO:0042088	T-helper 1 type immune response	1.102089e-3
GO:0032007	negative regulation of TOR signaling cascade	1.121289e-3
GO:0042117	monocyte activation	1.129648e-3
GO:0070670	response to interleukin-4	1.132009e-3
GO:0000212	meiotic spindle organization	1.132967e-3
GO:0061017	hepatoblast differentiation	1.137508e-3
GO:0001692	histamine metabolic process	1.139057e-3
GO:0045084	positive regulation of interleukin-12 biosynthetic process	1.157042e-3
GO:0008617	guanosine metabolic process	1.172133e-3
GO:0060014	granulosa cell differentiation	1.172133e-3
GO:0042866	pyruvate biosynthetic process	1.172133e-3
GO:0070079	histone H4-R3 demethylation	1.192548e-3
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	1.192548e-3
GO:0070078	histone H3-R2 demethylation	1.192548e-3
GO:0051491	positive regulation of filopodium assembly	1.197636e-3
GO:0010621	negative regulation of transcription by transcription factor localization	1.260163e-3
GO:0032656	regulation of interleukin-13 production	1.295829e-3
GO:0009637	response to blue light	1.303137e-3
GO:0030422	production of siRNA involved in RNA interference	1.303137e-3
GO:0048705	skeletal system morphogenesis	1.308509e-3
GO:0019724	B cell mediated immunity	1.308678e-3
GO:0051926	negative regulation of calcium ion transport	1.318502e-3
GO:0035104	positive regulation of transcription via sterol regulatory element binding	1.333087e-3
GO:0060611	mammary gland fat development	1.335148e-3
GO:0008277	regulation of G-protein coupled receptor protein signaling pathway	1.353498e-3
GO:0048263	determination of dorsal identity	1.353646e-3
GO:0022002	negative regulation of anterior neural cell fate commitment of the neural plate by Wnt receptor signaling pathway	1.353646e-3
GO:0035510	DNA dealkylation	1.358276e-3
GO:0046618	drug export	1.359931e-3
GO:0006090	pyruvate metabolic process	1.360331e-3
GO:0014040	positive regulation of Schwann cell differentiation	1.366502e-3
GO:0055026	negative regulation of cardiac muscle tissue development	1.370433e-3
GO:0060947	cardiac vascular smooth muscle cell differentiation	1.370433e-3
GO:0060450	positive regulation of hindgut contraction	1.376793e-3
GO:0045925	positive regulation of female receptivity	1.376793e-3
GO:0021933	radial glia guided migration of cerebellar granule cell	1.376793e-3
GO:0019402	galactitol metabolic process	1.408081e-3
GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus	1.408081e-3
GO:0009586	rhodopsin mediated phototransduction	1.427187e-3
GO:0072284	metanephric S-shaped body morphogenesis	1.431380e-3
GO:0060390	regulation of SMAD protein import into nucleus	1.432940e-3
GO:0000389	nuclear mRNA 3'-splice site recognition	1.442539e-3
GO:0048008	platelet-derived growth factor receptor signaling pathway	1.445552e-3
GO:0006110	regulation of glycolysis	1.465043e-3
GO:0002768	immune response-regulating cell surface receptor signaling pathway	1.466918e-3
GO:0045416	positive regulation of interleukin-8 biosynthetic process	1.466932e-3
GO:0061049	cell growth involved in cardiac muscle cell development	1.492318e-3
GO:0014873	response to muscle activity involved in regulation of muscle adaptation	1.492318e-3
GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure	1.492318e-3
GO:0003331	positive regulation of extracellular matrix constituent secretion	1.492318e-3
GO:0032754	positive regulation of interleukin-5 production	1.502448e-3
GO:0018879	biphenyl metabolic process	1.502448e-3
GO:0045616	regulation of keratinocyte differentiation	1.510683e-3
GO:0014075	response to amine stimulus	1.517565e-3
GO:0048708	astrocyte differentiation	1.593929e-3
GO:0007412	axon target recognition	1.606335e-3
GO:0071072	negative regulation of phospholipid biosynthetic process	1.613773e-3
GO:0019882	antigen processing and presentation	1.624059e-3
GO:0002027	regulation of heart rate	1.629934e-3
GO:0006606	protein import into nucleus	1.631493e-3
GO:0050432	catecholamine secretion	1.671978e-3
GO:0010718	positive regulation of epithelial to mesenchymal transition	1.681387e-3
GO:0023019	signal transduction involved in regulation of gene expression	1.694155e-3
GO:0002828	regulation of type 2 immune response	1.707433e-3
GO:0006002	fructose 6-phosphate metabolic process	1.752236e-3
GO:0043171	peptide catabolic process	1.752236e-3
GO:0035606	peptidyl-cysteine S-trans-nitrosylation	1.761793e-3
GO:0031953	negative regulation of protein autophosphorylation	1.789464e-3
GO:0045581	negative regulation of T cell differentiation	1.790243e-3
GO:0032964	collagen biosynthetic process	1.826995e-3
GO:0051130	positive regulation of cellular component organization	1.830847e-3
GO:0045338	farnesyl diphosphate metabolic process	1.846036e-3
GO:0032674	regulation of interleukin-5 production	1.862296e-3
GO:0003300	cardiac muscle hypertrophy	1.869746e-3
GO:0006760	folic acid-containing compound metabolic process	1.897300e-3
GO:0061379	inferior colliculus development	1.898211e-3
GO:0061381	cell migration in diencephalon	1.898211e-3
GO:0061374	mammillothalamic axonal tract development	1.898211e-3
GO:0021855	hypothalamus cell migration	1.898211e-3
GO:0061011	hepatic duct development	1.931523e-3
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	1.948522e-3
GO:0048790	maintenance of presynaptic active zone structure	2.008863e-3
GO:0015747	urate transport	2.008863e-3
GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane	2.008863e-3
GO:0033273	response to vitamin	2.023273e-3
GO:0035886	vascular smooth muscle cell differentiation	2.042179e-3
GO:0060644	mammary gland epithelial cell differentiation	2.062176e-3
GO:0002446	neutrophil mediated immunity	2.062925e-3
GO:0009584	detection of visible light	2.074721e-3
GO:0010520	regulation of reciprocal meiotic recombination	2.095572e-3
GO:0002432	granuloma formation	2.095572e-3
GO:0035691	macrophage migration inhibitory factor signaling pathway	2.106697e-3
GO:0000966	RNA 5'-end processing	2.106697e-3
GO:0046533	negative regulation of photoreceptor cell differentiation	2.148737e-3
GO:0023041	neuronal signal transduction	2.149259e-3
GO:0048635	negative regulation of muscle organ development	2.162261e-3
GO:0010544	negative regulation of platelet activation	2.174099e-3
GO:0080111	DNA demethylation	2.188009e-3
GO:0032649	regulation of interferon-gamma production	2.195024e-3
GO:0006754	ATP biosynthetic process	2.234459e-3
GO:0070669	response to interleukin-2	2.235075e-3
GO:0015817	histidine transport	2.246846e-3
GO:0002522	leukocyte migration involved in immune response	2.253131e-3
GO:0072179	nephric duct formation	2.258697e-3
GO:0033504	floor plate development	2.260624e-3
GO:0046425	regulation of JAK-STAT cascade	2.264462e-3
GO:0032461	positive regulation of protein oligomerization	2.295546e-3
GO:0034695	response to prostaglandin E stimulus	2.310412e-3
GO:0046532	regulation of photoreceptor cell differentiation	2.310412e-3
GO:0034635	glutathione transport	2.325985e-3
GO:0071335	hair follicle cell proliferation	2.325985e-3
GO:0032290	peripheral nervous system myelin formation	2.325985e-3
GO:0010189	vitamin E biosynthetic process	2.325985e-3
GO:0031503	protein complex localization	2.326202e-3
GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development	2.340134e-3
GO:0071299	cellular response to vitamin A	2.341927e-3
GO:0044236	multicellular organismal metabolic process	2.350650e-3
GO:0006400	tRNA modification	2.381397e-3
GO:0032464	positive regulation of protein homooligomerization	2.456723e-3
GO:0032233	positive regulation of actin filament bundle assembly	2.463023e-3
GO:0031064	negative regulation of histone deacetylation	2.477919e-3
GO:0006525	arginine metabolic process	2.483109e-3
GO:0045955	negative regulation of calcium ion-dependent exocytosis	2.505076e-3
GO:0010677	negative regulation of cellular carbohydrate metabolic process	2.508444e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0000303	response to superoxide	9.290672e-9
GO:0051764	actin crosslink formation	3.097949e-8
GO:0002149	hypochlorous acid biosynthetic process	1.194238e-7
GO:0006705	mineralocorticoid biosynthetic process	2.614398e-7
GO:0014819	regulation of skeletal muscle contraction	2.656377e-7
GO:0019430	removal of superoxide radicals	4.573696e-7
GO:0000305	response to oxygen radical	5.256411e-7
GO:0051138	positive regulation of NK T cell differentiation	6.944598e-7
GO:0002886	regulation of myeloid leukocyte mediated immunity	7.863442e-7
GO:0030157	pancreatic juice secretion	1.462312e-6
GO:0006189	'de novo' IMP biosynthetic process	1.515834e-6
GO:0060427	lung connective tissue development	2.109686e-6
GO:0000302	response to reactive oxygen species	2.390028e-6
GO:0045017	glycerolipid biosynthetic process	2.433520e-6
GO:0046514	ceramide catabolic process	2.625682e-6
GO:0055010	ventricular cardiac muscle tissue morphogenesis	2.943668e-6
GO:0003229	ventricular cardiac muscle tissue development	3.040761e-6
GO:0030149	sphingolipid catabolic process	3.669954e-6
GO:0050832	defense response to fungus	4.822276e-6
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	6.468448e-6
GO:0042542	response to hydrogen peroxide	6.743402e-6
GO:0015074	DNA integration	7.218472e-6
GO:0019731	antibacterial humoral response	8.431475e-6
GO:0006734	NADH metabolic process	8.917280e-6
GO:0006188	IMP biosynthetic process	1.331601e-5
GO:0043534	blood vessel endothelial cell migration	1.357402e-5
GO:0090076	relaxation of skeletal muscle	1.455180e-5
GO:0032470	elevation of endoplasmic reticulum calcium ion concentration	1.455180e-5
GO:0043314	negative regulation of neutrophil degranulation	2.361946e-5
GO:0060442	branching involved in prostate gland morphogenesis	2.377613e-5
GO:0051013	microtubule severing	2.511880e-5
GO:0033382	maintenance of granzyme B location in T cell secretory granule	2.815625e-5
GO:0033373	maintenance of protease location in mast cell secretory granule	2.815625e-5
GO:0006801	superoxide metabolic process	2.897100e-5
GO:0017157	regulation of exocytosis	2.983015e-5
GO:0043300	regulation of leukocyte degranulation	3.140717e-5
GO:0002679	respiratory burst involved in defense response	3.427057e-5
GO:0048537	mucosal-associated lymphoid tissue development	3.714870e-5
GO:0002432	granuloma formation	4.086707e-5
GO:0043313	regulation of neutrophil degranulation	4.586723e-5
GO:0035967	cellular response to topologically incorrect protein	5.047311e-5
GO:0034505	tooth mineralization	5.065325e-5
GO:0043542	endothelial cell migration	5.220193e-5
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	5.750038e-5
GO:0032855	positive regulation of Rac GTPase activity	5.934025e-5
GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation	6.297021e-5
GO:0019730	antimicrobial humoral response	6.687528e-5
GO:0043154	negative regulation of caspase activity	6.753684e-5
GO:0006707	cholesterol catabolic process	6.760990e-5
GO:0002455	humoral immune response mediated by circulating immunoglobulin	6.823444e-5
GO:0001957	intramembranous ossification	7.081325e-5
GO:0006646	phosphatidylethanolamine biosynthetic process	7.441201e-5
GO:0045988	negative regulation of striated muscle contraction	7.571274e-5
GO:0035247	peptidyl-arginine omega-N-methylation	7.891618e-5
GO:0006650	glycerophospholipid metabolic process	8.615653e-5
GO:0009124	nucleoside monophosphate biosynthetic process	8.712430e-5
GO:0034614	cellular response to reactive oxygen species	8.921098e-5
GO:0046474	glycerophospholipid biosynthetic process	9.147343e-5
GO:0050432	catecholamine secretion	1.134701e-4
GO:0045989	positive regulation of striated muscle contraction	1.138548e-4
GO:0031448	positive regulation of fast-twitch skeletal muscle fiber contraction	1.157720e-4
GO:0034616	response to laminar fluid shear stress	1.310117e-4
GO:0018195	peptidyl-arginine modification	1.375253e-4
GO:0045655	regulation of monocyte differentiation	1.378689e-4
GO:0032321	positive regulation of Rho GTPase activity	1.532804e-4
GO:0046339	diacylglycerol metabolic process	1.579734e-4
GO:0072539	T-helper 17 cell differentiation	1.613035e-4
GO:0097039	protein linear polyubiquitination	1.614642e-4
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.614642e-4
GO:0034375	high-density lipoprotein particle remodeling	1.692224e-4
GO:0034969	histone arginine methylation	1.696672e-4
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.737169e-4
GO:0019432	triglyceride biosynthetic process	1.760906e-4
GO:0045933	positive regulation of muscle contraction	1.817700e-4
GO:0090185	negative regulation of kidney development	2.083174e-4
GO:0043691	reverse cholesterol transport	2.095456e-4
GO:0021631	optic nerve morphogenesis	2.116587e-4
GO:0046340	diacylglycerol catabolic process	2.204348e-4
GO:0045658	regulation of neutrophil differentiation	2.339314e-4
GO:0002551	mast cell chemotaxis	2.366428e-4
GO:0046486	glycerolipid metabolic process	2.519849e-4
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.583863e-4
GO:0048007	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	2.638051e-4
GO:0060527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	2.669243e-4
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	2.669243e-4
GO:0033364	mast cell secretory granule organization	2.713529e-4
GO:0019882	antigen processing and presentation	3.253062e-4
GO:0048242	epinephrine secretion	3.435091e-4
GO:0043089	positive regulation of Cdc42 GTPase activity	3.536899e-4
GO:0009167	purine ribonucleoside monophosphate metabolic process	3.549722e-4
GO:0035066	positive regulation of histone acetylation	3.594570e-4
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	3.897044e-4
GO:0030166	proteoglycan biosynthetic process	3.932643e-4
GO:0071529	cementum mineralization	3.938834e-4
GO:0045217	cell-cell junction maintenance	3.954850e-4
GO:0048535	lymph node development	4.024149e-4
GO:0046504	glycerol ether biosynthetic process	4.108497e-4
GO:0060620	regulation of cholesterol import	4.305586e-4
GO:0045660	positive regulation of neutrophil differentiation	4.400074e-4
GO:0017158	regulation of calcium ion-dependent exocytosis	4.483732e-4
GO:0006656	phosphatidylcholine biosynthetic process	4.563291e-4
GO:0046112	nucleobase biosynthetic process	4.768169e-4
GO:0035966	response to topologically incorrect protein	4.797855e-4
GO:0035246	peptidyl-arginine N-methylation	4.875654e-4
GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	5.044396e-4
GO:0046470	phosphatidylcholine metabolic process	5.089031e-4
GO:0034369	plasma lipoprotein particle remodeling	5.097094e-4
GO:0034976	response to endoplasmic reticulum stress	5.118469e-4
GO:0032094	response to food	5.156851e-4
GO:0018216	peptidyl-arginine methylation	5.172965e-4
GO:0002740	negative regulation of cytokine secretion involved in immune response	5.205820e-4
GO:0050965	detection of temperature stimulus involved in sensory perception of pain	5.234320e-4
GO:0001935	endothelial cell proliferation	5.469940e-4
GO:0046463	acylglycerol biosynthetic process	5.480728e-4
GO:0050951	sensory perception of temperature stimulus	5.518276e-4
GO:0003339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	5.628559e-4
GO:0008654	phospholipid biosynthetic process	5.902096e-4
GO:0090224	regulation of spindle organization	6.146431e-4
GO:0045792	negative regulation of cell size	6.146431e-4
GO:0071218	cellular response to misfolded protein	6.194799e-4
GO:0000072	M phase specific microtubule process	6.194799e-4
GO:0072183	negative regulation of nephron tubule epithelial cell differentiation	6.234502e-4
GO:0002678	positive regulation of chronic inflammatory response	6.490997e-4
GO:0048241	epinephrine transport	6.544846e-4
GO:0042744	hydrogen peroxide catabolic process	6.611528e-4
GO:0045730	respiratory burst	6.659767e-4
GO:0009113	purine base biosynthetic process	6.775551e-4
GO:0031943	regulation of glucocorticoid metabolic process	7.028881e-4
GO:0070301	cellular response to hydrogen peroxide	7.218098e-4
GO:0070845	polyubiquitinated misfolded protein transport	7.253359e-4
GO:0031914	negative regulation of synaptic plasticity	7.253359e-4
GO:0009134	nucleoside diphosphate catabolic process	7.255543e-4
GO:0042439	ethanolamine-containing compound metabolic process	7.325789e-4
GO:0018192	enzyme active site formation via L-cysteine persulfide	7.420751e-4
GO:0006839	mitochondrial transport	7.624018e-4
GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter	7.885868e-4
GO:0006102	isocitrate metabolic process	7.885868e-4
GO:0006986	response to unfolded protein	8.111442e-4
GO:0045948	positive regulation of translational initiation	8.627582e-4
GO:0090075	relaxation of muscle	8.839878e-4
GO:0051898	negative regulation of protein kinase B signaling cascade	9.115595e-4
GO:0070508	cholesterol import	9.172581e-4
GO:0032222	regulation of synaptic transmission, cholinergic	9.222059e-4
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	9.241193e-4
GO:0002885	positive regulation of hypersensitivity	9.256206e-4
GO:0051693	actin filament capping	9.360395e-4
GO:0042311	vasodilation	9.438980e-4
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	9.470384e-4
GO:0043088	regulation of Cdc42 GTPase activity	9.773762e-4
GO:0007109	cytokinesis, completion of separation	9.986074e-4
GO:0007596	blood coagulation	1.010684e-3
GO:0006937	regulation of muscle contraction	1.045310e-3
GO:0006164	purine nucleotide biosynthetic process	1.048004e-3
GO:0044243	multicellular organismal catabolic process	1.049095e-3
GO:0006110	regulation of glycolysis	1.050320e-3
GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	1.052934e-3
GO:0031167	rRNA methylation	1.128763e-3
GO:0009408	response to heat	1.156862e-3
GO:0009161	ribonucleoside monophosphate metabolic process	1.164155e-3
GO:0009266	response to temperature stimulus	1.194789e-3
GO:0031642	negative regulation of myelination	1.209238e-3
GO:0021562	vestibulocochlear nerve development	1.221404e-3
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.229022e-3
GO:0033037	polysaccharide localization	1.229022e-3
GO:0042268	regulation of cytolysis	1.240082e-3
GO:0000387	spliceosomal snRNP assembly	1.240082e-3
GO:0042743	hydrogen peroxide metabolic process	1.252012e-3
GO:0060307	regulation of ventricular cardiomyocyte membrane repolarization	1.256938e-3
GO:0060299	negative regulation of sarcomere organization	1.256938e-3
GO:0051977	lysophospholipid transport	1.256938e-3
GO:0042228	interleukin-8 biosynthetic process	1.256938e-3
GO:0033002	muscle cell proliferation	1.268242e-3
GO:0048711	positive regulation of astrocyte differentiation	1.295700e-3
GO:0090207	regulation of triglyceride metabolic process	1.297864e-3
GO:0035023	regulation of Rho protein signal transduction	1.297974e-3
GO:0046426	negative regulation of JAK-STAT cascade	1.307302e-3
GO:0072593	reactive oxygen species metabolic process	1.367876e-3
GO:0035094	response to nicotine	1.393535e-3
GO:0019233	sensory perception of pain	1.401139e-3
GO:0006984	ER-nucleus signaling pathway	1.442202e-3
GO:0070831	basement membrane assembly	1.460873e-3
GO:0043471	regulation of cellular carbohydrate catabolic process	1.473752e-3
GO:0051561	elevation of mitochondrial calcium ion concentration	1.477366e-3
GO:0034227	tRNA thio-modification	1.493256e-3
GO:0006927	transformed cell apoptosis	1.512152e-3
GO:0010575	positive regulation vascular endothelial growth factor production	1.516474e-3
GO:0006084	acetyl-CoA metabolic process	1.574369e-3
GO:0072333	signal transduction by p53 class mediator resulting in induction of anoikis	1.618660e-3
GO:0030101	natural killer cell activation	1.625550e-3
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	1.650600e-3
GO:0030835	negative regulation of actin filament depolymerization	1.693175e-3
GO:0006883	cellular sodium ion homeostasis	1.706678e-3
GO:0045686	negative regulation of glial cell differentiation	1.726936e-3
GO:0045861	negative regulation of proteolysis	1.732066e-3
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	1.735741e-3
GO:0007586	digestion	1.743343e-3
GO:0050655	dermatan sulfate proteoglycan metabolic process	1.767199e-3
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	1.770992e-3
GO:0001887	selenium compound metabolic process	1.770992e-3
GO:0007599	hemostasis	1.850076e-3
GO:0031946	regulation of glucocorticoid biosynthetic process	1.857130e-3
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	1.909770e-3
GO:0030968	endoplasmic reticulum unfolded protein response	1.985708e-3
GO:0043301	negative regulation of leukocyte degranulation	2.004699e-3
GO:0050878	regulation of body fluid levels	2.012764e-3
GO:0019637	organophosphate metabolic process	2.023452e-3
GO:0051580	regulation of neurotransmitter uptake	2.086251e-3
GO:0071827	plasma lipoprotein particle organization	2.092826e-3
GO:0030837	negative regulation of actin filament polymerization	2.103132e-3
GO:0001886	endothelial cell morphogenesis	2.122208e-3
GO:0001798	positive regulation of type IIa hypersensitivity	2.155074e-3
GO:0043491	protein kinase B signaling cascade	2.199147e-3
GO:0060707	trophoblast giant cell differentiation	2.236109e-3
GO:0032506	cytokinetic process	2.273676e-3
GO:0055017	cardiac muscle tissue growth	2.298733e-3
GO:0010896	regulation of triglyceride catabolic process	2.309076e-3
GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein	2.321063e-3
GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein	2.326063e-3
GO:0031947	negative regulation of glucocorticoid biosynthetic process	2.326063e-3
GO:0019532	oxalate transport	2.370467e-3
GO:0006958	complement activation, classical pathway	2.427862e-3
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling	2.445184e-3
GO:0002051	osteoblast fate commitment	2.445184e-3
GO:0070243	regulation of thymocyte apoptosis	2.461777e-3
GO:0051541	elastin metabolic process	2.503582e-3
GO:0060621	negative regulation of cholesterol import	2.503582e-3
GO:0002475	antigen processing and presentation via MHC class Ib	2.503582e-3
GO:0046847	filopodium assembly	2.514357e-3
GO:0032963	collagen metabolic process	2.514820e-3
GO:0006099	tricarboxylic acid cycle	2.544914e-3
GO:0006144	purine base metabolic process	2.586898e-3
GO:0035907	dorsal aorta development	2.660939e-3
GO:0051241	negative regulation of multicellular organismal process	2.741487e-3
GO:0006942	regulation of striated muscle contraction	2.773524e-3
GO:0002248	connective tissue replacement involved in inflammatory response wound healing	2.810363e-3
GO:0046356	acetyl-CoA catabolic process	2.852043e-3
GO:0010982	regulation of high-density lipoprotein particle clearance	2.858766e-3
GO:0071299	cellular response to vitamin A	2.873002e-3
GO:0072267	metanephric capsule specification	2.896787e-3
GO:2000657	negative regulation of apolipoprotein binding	2.896787e-3
GO:0046986	negative regulation of hemoglobin biosynthetic process	2.896787e-3
GO:0006409	tRNA export from nucleus	2.896787e-3
GO:0006756	AMP phosphorylation	2.913885e-3
GO:0032863	activation of Rac GTPase activity	2.924925e-3
GO:0009191	ribonucleoside diphosphate catabolic process	2.924925e-3
GO:0009190	cyclic nucleotide biosynthetic process	2.938900e-3
GO:0030046	parallel actin filament bundle assembly	2.945496e-3
GO:0071874	cellular response to norepinephrine stimulus	2.951598e-3
GO:0006407	rRNA export from nucleus	2.995448e-3
GO:0006438	valyl-tRNA aminoacylation	2.995448e-3
GO:0002739	regulation of cytokine secretion involved in immune response	3.025544e-3
GO:0021555	midbrain-hindbrain boundary morphogenesis	3.029113e-3
GO:0001710	mesodermal cell fate commitment	3.062347e-3
GO:0060997	dendritic spine morphogenesis	3.079174e-3
GO:2001054	negative regulation of mesenchymal cell apoptosis	3.084508e-3
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	3.111111e-3
GO:0055009	atrial cardiac muscle tissue morphogenesis	3.129486e-3
GO:0048541	Peyer's patch development	3.130179e-3
GO:0021903	rostrocaudal neural tube patterning	3.137482e-3
GO:0009156	ribonucleoside monophosphate biosynthetic process	3.144776e-3
GO:0070328	triglyceride homeostasis	3.186967e-3
GO:0030174	regulation of DNA-dependent DNA replication initiation	3.259494e-3
GO:0009165	nucleotide biosynthetic process	3.282453e-3
GO:0003062	regulation of heart rate by chemical signal	3.325277e-3
GO:0031670	cellular response to nutrient	3.332000e-3
GO:0006515	misfolded or incompletely synthesized protein catabolic process	3.352206e-3
GO:0009117	nucleotide metabolic process	3.368738e-3
GO:0060346	bone trabecula formation	3.442175e-3
GO:0071300	cellular response to retinoic acid	3.487290e-3
GO:0042398	cellular modified amino acid biosynthetic process	3.520498e-3
GO:0010830	regulation of myotube differentiation	3.547698e-3
GO:0030917	midbrain-hindbrain boundary development	3.553972e-3
GO:0051029	rRNA transport	3.581132e-3
GO:0002528	regulation of vascular permeability involved in acute inflammatory response	3.623859e-3
GO:0048144	fibroblast proliferation	3.623859e-3
GO:0030574	collagen catabolic process	3.655028e-3
GO:0060419	heart growth	3.711165e-3
GO:0032796	uropod organization	3.743088e-3
GO:0072522	purine-containing compound biosynthetic process	3.747904e-3
GO:0045606	positive regulation of epidermal cell differentiation	3.797296e-3
GO:0030300	regulation of intestinal cholesterol absorption	3.858939e-3
GO:0006171	cAMP biosynthetic process	3.858939e-3
GO:0060193	positive regulation of lipase activity	3.872572e-3
GO:0031645	negative regulation of neurological system process	3.926063e-3
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	3.940181e-3
GO:0072668	tubulin complex biogenesis	3.976153e-3
GO:0016048	detection of temperature stimulus	4.000366e-3
GO:0045657	positive regulation of monocyte differentiation	4.000366e-3
GO:0006654	phosphatidic acid biosynthetic process	4.189800e-3
GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein	4.190218e-3
GO:0003065	positive regulation of heart rate by epinephrine	4.190218e-3
GO:0035813	regulation of renal sodium excretion	4.218651e-3
GO:0019674	NAD metabolic process	4.240903e-3
GO:0072098	anterior/posterior pattern specification involved in kidney development	4.242092e-3
GO:0072003	kidney rudiment formation	4.242092e-3
GO:0042732	D-xylose metabolic process	4.242092e-3
GO:0048389	intermediate mesoderm development	4.242092e-3
GO:0000060	protein import into nucleus, translocation	4.246731e-3
GO:0030502	negative regulation of bone mineralization	4.272501e-3
GO:0046940	nucleoside monophosphate phosphorylation	4.403022e-3
GO:0035912	dorsal aorta morphogenesis	4.403022e-3
GO:0030038	contractile actin filament bundle assembly	4.403022e-3
GO:0051187	cofactor catabolic process	4.416343e-3
GO:0031638	zymogen activation	4.530551e-3
GO:0072199	regulation of mesenchymal cell proliferation involved in ureter development	4.681469e-3
GO:0051590	positive regulation of neurotransmitter transport	4.681469e-3
GO:0006626	protein targeting to mitochondrion	4.750461e-3
GO:0030035	microspike assembly	4.766408e-3
GO:0021502	neural fold elevation formation	4.814531e-3
GO:0030388	fructose 1,6-bisphosphate metabolic process	4.819984e-3
GO:0021554	optic nerve development	4.837398e-3
GO:0009109	coenzyme catabolic process	4.930871e-3
GO:0003093	regulation of glomerular filtration	4.946495e-3
GO:0045932	negative regulation of muscle contraction	4.951603e-3
GO:0009123	nucleoside monophosphate metabolic process	5.028517e-3
GO:0051168	nuclear export	5.051445e-3
GO:0045639	positive regulation of myeloid cell differentiation	5.099730e-3
GO:0072300	positive regulation of metanephric glomerulus development	5.131220e-3
GO:0045618	positive regulation of keratinocyte differentiation	5.131220e-3
GO:0016045	detection of bacterium	5.165276e-3
GO:0007021	tubulin complex assembly	5.165276e-3
GO:0003018	vascular process in circulatory system	5.171070e-3
GO:0034441	plasma lipoprotein particle oxidation	5.190865e-3
GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	5.206112e-3
GO:0048710	regulation of astrocyte differentiation	5.250028e-3
GO:0070232	regulation of T cell apoptosis	5.319429e-3
GO:0032012	regulation of ARF protein signal transduction	5.385180e-3
GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	5.426581e-3
GO:0010894	negative regulation of steroid biosynthetic process	5.495401e-3
GO:0051006	positive regulation of lipoprotein lipase activity	5.546546e-3
GO:0042541	hemoglobin biosynthetic process	5.546546e-3
GO:0032781	positive regulation of ATPase activity	5.553825e-3
GO:0034380	high-density lipoprotein particle assembly	5.579363e-3
GO:0033363	secretory granule organization	5.579363e-3
GO:0060996	dendritic spine development	5.636339e-3
GO:0045920	negative regulation of exocytosis	5.652991e-3
GO:0009404	toxin metabolic process	5.679461e-3
GO:0021801	cerebral cortex radial glia guided migration	5.708875e-3
GO:0070509	calcium ion import	5.711190e-3
GO:0034654	nucleobase-containing compound biosynthetic process	5.730006e-3
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	5.747394e-3
GO:0051725	protein de-ADP-ribosylation	5.747394e-3
GO:0002071	glandular epithelial cell maturation	5.747394e-3
GO:0006644	phospholipid metabolic process	5.754369e-3
GO:0033137	negative regulation of peptidyl-serine phosphorylation	5.891082e-3
GO:0090257	regulation of muscle system process	5.932511e-3
GO:2000309	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production	5.934495e-3
GO:0061360	optic chiasma development	5.934495e-3
GO:2000597	positive regulation of optic nerve formation	5.934495e-3
GO:0021633	optic nerve structural organization	5.934495e-3
GO:0021650	vestibulocochlear nerve formation	5.934495e-3
GO:0035799	ureter maturation	5.934495e-3
GO:0010872	regulation of cholesterol esterification	5.936024e-3
GO:0055118	negative regulation of cardiac muscle contraction	5.953486e-3
GO:0007386	compartment pattern specification	5.953486e-3
GO:0006979	response to oxidative stress	6.021585e-3
GO:0045687	positive regulation of glial cell differentiation	6.022420e-3
GO:0009260	ribonucleotide biosynthetic process	6.023010e-3
GO:0006405	RNA export from nucleus	6.091323e-3
GO:0045453	bone resorption	6.125143e-3
GO:0046984	regulation of hemoglobin biosynthetic process	6.125317e-3
GO:0043304	regulation of mast cell degranulation	6.129674e-3
GO:0009259	ribonucleotide metabolic process	6.161592e-3
GO:0046479	glycosphingolipid catabolic process	6.185748e-3
GO:0090193	positive regulation of glomerulus development	6.185748e-3
GO:0050710	negative regulation of cytokine secretion	6.220436e-3
GO:0002444	myeloid leukocyte mediated immunity	6.387303e-3
GO:0003231	cardiac ventricle development	6.416643e-3
GO:0042249	establishment of planar polarity of embryonic epithelium	6.459052e-3
GO:2000145	regulation of cell motility	6.509883e-3
GO:0042346	positive regulation of NF-kappaB import into nucleus	6.629348e-3
GO:0034599	cellular response to oxidative stress	6.655363e-3
GO:0043252	sodium-independent organic anion transport	6.675974e-3
GO:0045609	positive regulation of auditory receptor cell differentiation	6.675974e-3
GO:0042667	auditory receptor cell fate specification	6.675974e-3
GO:0016078	tRNA catabolic process	6.675974e-3
GO:0001682	tRNA 5'-leader removal	6.675974e-3
GO:0030834	regulation of actin filament depolymerization	6.694770e-3
GO:0072376	protein activation cascade	6.743951e-3
GO:0060291	long-term synaptic potentiation	6.750521e-3
GO:0046131	pyrimidine ribonucleoside metabolic process	6.752020e-3
GO:0010614	negative regulation of cardiac muscle hypertrophy	6.765345e-3
GO:0044236	multicellular organismal metabolic process	6.851561e-3
GO:0060687	regulation of branching involved in prostate gland morphogenesis	6.897247e-3
GO:0030433	ER-associated protein catabolic process	6.923762e-3
GO:0072141	renal interstitial cell development	6.930540e-3
GO:0060084	synaptic transmission involved in micturition	6.949331e-3
GO:0014057	positive regulation of acetylcholine secretion	6.949331e-3
GO:0071295	cellular response to vitamin	6.984433e-3
GO:0072305	negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis	7.015591e-3
GO:2000594	positive regulation of metanephric DCT cell differentiation	7.015591e-3
GO:0039003	pronephric field specification	7.015591e-3
GO:0014874	response to stimulus involved in regulation of muscle adaptation	7.062045e-3
GO:0003071	renal system process involved in regulation of systemic arterial blood pressure	7.106079e-3
GO:0048013	ephrin receptor signaling pathway	7.136463e-3
GO:0072161	mesenchymal cell differentiation involved in kidney development	7.186053e-3
GO:0043171	peptide catabolic process	7.186053e-3
GO:0070168	negative regulation of biomineral tissue development	7.250408e-3
GO:0010863	positive regulation of phospholipase C activity	7.279705e-3
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	7.355163e-3
GO:2000249	regulation of actin cytoskeleton reorganization	7.366466e-3
GO:0007006	mitochondrial membrane organization	7.375055e-3
GO:0032648	regulation of interferon-beta production	7.376097e-3
GO:0006706	steroid catabolic process	7.394627e-3
GO:0032608	interferon-beta production	7.437922e-3
GO:0046963	3'-phosphoadenosine 5'-phosphosulfate transport	7.437922e-3
GO:0001977	renal system process involved in regulation of blood volume	7.596659e-3
GO:0003219	cardiac right ventricle formation	7.596823e-3
GO:0006956	complement activation	7.607197e-3
GO:0060080	regulation of inhibitory postsynaptic membrane potential	7.632790e-3
GO:0003160	endocardium morphogenesis	7.632790e-3
GO:0015858	nucleoside transport	7.720599e-3
GO:0009152	purine ribonucleotide biosynthetic process	7.760465e-3
GO:2000210	positive regulation of anoikis	7.767124e-3
GO:0030325	adrenal gland development	7.791330e-3
GO:0031329	regulation of cellular catabolic process	7.844395e-3
GO:0045218	zonula adherens maintenance	7.852252e-3
GO:0008277	regulation of G-protein coupled receptor protein signaling pathway	7.912589e-3
GO:0010677	negative regulation of cellular carbohydrate metabolic process	8.142643e-3
GO:0051492	regulation of stress fiber assembly	8.154591e-3
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	8.241593e-3
GO:0006391	transcription initiation from mitochondrial promoter	8.241593e-3
GO:0031214	biomineral tissue development	8.352121e-3
GO:0060214	endocardium formation	8.466144e-3
GO:0032418	lysosome localization	8.630130e-3
GO:0019344	cysteine biosynthetic process	8.630130e-3
GO:0015722	canalicular bile acid transport	8.630130e-3
GO:0030953	astral microtubule organization	8.766994e-3
GO:0003218	cardiac left ventricle formation	8.766994e-3
GO:0061043	regulation of vascular wound healing	8.870714e-3
GO:0021813	cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration	8.870714e-3
GO:0000920	cytokinetic cell separation	9.037360e-3
GO:0050713	negative regulation of interleukin-1 beta secretion	9.037360e-3
GO:0055086	nucleobase-containing small molecule metabolic process	9.053697e-3
GO:0014015	positive regulation of gliogenesis	9.081516e-3
GO:0051494	negative regulation of cytoskeleton organization	9.307390e-3
GO:0042396	phosphagen biosynthetic process	9.347035e-3
GO:0048280	vesicle fusion with Golgi apparatus	9.347035e-3
GO:0014904	myotube cell development	9.347035e-3
GO:0010987	negative regulation of high-density lipoprotein particle clearance	9.347035e-3
GO:0010897	negative regulation of triglyceride catabolic process	9.347035e-3
GO:0043462	regulation of ATPase activity	9.433527e-3
GO:0010812	negative regulation of cell-substrate adhesion	9.474288e-3
GO:0034629	cellular protein complex localization	9.492988e-3
GO:0060292	long term synaptic depression	9.633473e-3
GO:0014014	negative regulation of gliogenesis	9.665067e-3
GO:0048167	regulation of synaptic plasticity	9.667876e-3
GO:0010574	regulation of vascular endothelial growth factor production	9.688689e-3
GO:0050729	positive regulation of inflammatory response	9.691399e-3
GO:0060017	parathyroid gland development	9.845857e-3
GO:0032272	negative regulation of protein polymerization	9.888179e-3
GO:0009912	auditory receptor cell fate commitment	9.901359e-3
GO:0031333	negative regulation of protein complex assembly	9.991884e-3
GO:0046931	pore complex assembly	1.000281e-2
GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	1.000281e-2
GO:0032224	positive regulation of synaptic transmission, cholinergic	1.000281e-2
GO:0045656	negative regulation of monocyte differentiation	1.000281e-2
GO:0016926	protein desumoylation	1.000281e-2
GO:0042273	ribosomal large subunit biogenesis	1.010844e-2
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	1.015072e-2
GO:0006662	glycerol ether metabolic process	1.016645e-2
GO:0006689	ganglioside catabolic process	1.020896e-2
GO:0009649	entrainment of circadian clock	1.020954e-2
GO:0001969	regulation of activation of membrane attack complex	1.020954e-2
GO:0060389	pathway-restricted SMAD protein phosphorylation	1.022013e-2
GO:0071956	cellular component maintenance at cellular level	1.026166e-2
GO:0072172	mesonephric tubule formation	1.029236e-2
GO:0001842	neural fold formation	1.031657e-2
GO:0042501	serine phosphorylation of STAT protein	1.059868e-2
GO:0030091	protein repair	1.059868e-2
GO:0001956	positive regulation of neurotransmitter secretion	1.059868e-2
GO:0051030	snRNA transport	1.064890e-2
GO:0010312	detoxification of zinc ion	1.064890e-2
GO:0005997	xylulose metabolic process	1.064890e-2
GO:0071260	cellular response to mechanical stimulus	1.078891e-2
GO:0006821	chloride transport	1.084788e-2
GO:0043299	leukocyte degranulation	1.093240e-2
GO:2000696	regulation of epithelial cell differentiation involved in kidney development	1.099749e-2
GO:0033602	negative regulation of dopamine secretion	1.113676e-2
GO:0046949	fatty-acyl-CoA biosynthetic process	1.118922e-2
GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	1.118922e-2
GO:0061049	cell growth involved in cardiac muscle cell development	1.118922e-2
GO:0003331	positive regulation of extracellular matrix constituent secretion	1.118922e-2
GO:0008065	establishment of blood-nerve barrier	1.118922e-2
GO:0014873	response to muscle activity involved in regulation of muscle adaptation	1.118922e-2
GO:0021919	BMP signaling pathway involved in spinal cord dorsal/ventral patterning	1.118922e-2
GO:0060525	prostate glandular acinus development	1.129798e-2
GO:0072189	ureter development	1.131040e-2
GO:0030334	regulation of cell migration	1.137673e-2
GO:0090234	regulation of kinetochore assembly	1.144092e-2
GO:0009313	oligosaccharide catabolic process	1.144092e-2
GO:0090169	regulation of spindle assembly	1.144092e-2
GO:0006518	peptide metabolic process	1.182742e-2
GO:0044259	multicellular organismal macromolecule metabolic process	1.190708e-2
GO:0044271	cellular nitrogen compound biosynthetic process	1.203434e-2
GO:0006750	glutathione biosynthetic process	1.223651e-2
GO:0010976	positive regulation of neuron projection development	1.225308e-2
GO:0006959	humoral immune response	1.246312e-2
GO:0060463	lung lobe morphogenesis	1.250681e-2
GO:0043243	positive regulation of protein complex disassembly	1.250681e-2