Novel motif:53

name:	motif53_ANGCTG

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	5.416657e-15
GO:0031440	regulation of mRNA 3'-end processing	1.022647e-12
GO:0031442	positive regulation of mRNA 3'-end processing	1.923953e-11
GO:0050685	positive regulation of mRNA processing	4.063278e-11
GO:0061014	positive regulation of mRNA catabolic process	2.032145e-10
GO:0061013	regulation of mRNA catabolic process	2.039313e-9
GO:0010625	positive regulation of Schwann cell proliferation	6.473005e-9
GO:0001885	endothelial cell development	1.297141e-8
GO:0000387	spliceosomal snRNP assembly	4.924375e-8
GO:0042424	catecholamine catabolic process	6.525988e-8
GO:0032012	regulation of ARF protein signal transduction	7.331988e-8
GO:0060837	blood vessel endothelial cell differentiation	1.006810e-7
GO:0045446	endothelial cell differentiation	1.615150e-7
GO:0060020	Bergmann glial cell differentiation	1.641525e-7
GO:0090130	tissue migration	2.393919e-7
GO:0045112	integrin biosynthetic process	3.390326e-7
GO:0051580	regulation of neurotransmitter uptake	3.544203e-7
GO:0008078	mesodermal cell migration	3.861048e-7
GO:0035814	negative regulation of renal sodium excretion	4.547045e-7
GO:0060014	granulosa cell differentiation	5.006327e-7
GO:0032855	positive regulation of Rac GTPase activity	5.064718e-7
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	5.370957e-7
GO:0042703	menstruation	1.094838e-6
GO:0019101	female somatic sex determination	1.094838e-6
GO:0051898	negative regulation of protein kinase B signaling cascade	1.158738e-6
GO:0034048	negative regulation of protein phosphatase type 2A activity	1.250801e-6
GO:0021526	medial motor column neuron differentiation	1.384900e-6
GO:0035572	N-terminal peptidyl-serine dimethylation	1.388004e-6
GO:0035573	N-terminal peptidyl-serine trimethylation	1.388004e-6
GO:0018016	N-terminal peptidyl-proline dimethylation	1.388004e-6
GO:0018012	N-terminal peptidyl-alanine trimethylation	1.388004e-6
GO:0032088	negative regulation of NF-kappaB transcription factor activity	1.955509e-6
GO:0019083	viral transcription	2.137911e-6
GO:0051546	keratinocyte migration	2.211165e-6
GO:0006415	translational termination	2.289279e-6
GO:0042069	regulation of catecholamine metabolic process	2.498402e-6
GO:0032007	negative regulation of TOR signaling cascade	2.686480e-6
GO:0032321	positive regulation of Rho GTPase activity	2.722188e-6
GO:0030237	female sex determination	3.547869e-6
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	4.171292e-6
GO:0002074	extraocular skeletal muscle development	4.289260e-6
GO:0002604	regulation of dendritic cell antigen processing and presentation	4.928143e-6
GO:0070417	cellular response to cold	4.983520e-6
GO:0051085	chaperone mediated protein folding requiring cofactor	5.187296e-6
GO:0006636	unsaturated fatty acid biosynthetic process	5.441959e-6
GO:0006691	leukotriene metabolic process	5.628027e-6
GO:0045606	positive regulation of epidermal cell differentiation	6.495008e-6
GO:0043241	protein complex disassembly	7.480679e-6
GO:0042420	dopamine catabolic process	8.306696e-6
GO:0042053	regulation of dopamine metabolic process	8.412563e-6
GO:0019058	viral infectious cycle	8.505014e-6
GO:0006772	thiamine metabolic process	8.711243e-6
GO:0045618	positive regulation of keratinocyte differentiation	8.711243e-6
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	8.801853e-6
GO:0046456	icosanoid biosynthetic process	9.501976e-6
GO:0015993	molecular hydrogen transport	9.847401e-6
GO:0042488	positive regulation of odontogenesis of dentine-containing tooth	1.101776e-5
GO:0000086	G2/M transition of mitotic cell cycle	1.216253e-5
GO:0003158	endothelium development	1.281011e-5
GO:0060611	mammary gland fat development	1.281754e-5
GO:0007509	mesoderm migration involved in gastrulation	1.419241e-5
GO:0043088	regulation of Cdc42 GTPase activity	1.456829e-5
GO:0071421	manganese ion transmembrane transport	1.481167e-5
GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	1.568127e-5
GO:0019370	leukotriene biosynthetic process	1.682916e-5
GO:0035307	positive regulation of protein dephosphorylation	1.727336e-5
GO:0046718	entry of virus into host cell	1.759787e-5
GO:0008156	negative regulation of DNA replication	1.979238e-5
GO:0070561	vitamin D receptor signaling pathway	1.981374e-5
GO:0055010	ventricular cardiac muscle tissue morphogenesis	2.049202e-5
GO:0051156	glucose 6-phosphate metabolic process	2.249469e-5
GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	2.312400e-5
GO:0015936	coenzyme A metabolic process	2.351249e-5
GO:0031282	regulation of guanylate cyclase activity	2.361380e-5
GO:0032695	negative regulation of interleukin-12 production	2.394156e-5
GO:0071603	endothelial cell-cell adhesion	2.699123e-5
GO:0002002	regulation of angiotensin levels in blood	2.708507e-5
GO:0032515	negative regulation of phosphoprotein phosphatase activity	2.730465e-5
GO:0035304	regulation of protein dephosphorylation	3.178078e-5
GO:0045085	negative regulation of interleukin-2 biosynthetic process	3.388999e-5
GO:2000660	negative regulation of interleukin-1-mediated signaling pathway	3.400188e-5
GO:0030010	establishment of cell polarity	3.505393e-5
GO:0008366	axon ensheathment	3.520188e-5
GO:0006414	translational elongation	3.647108e-5
GO:0035306	positive regulation of dephosphorylation	4.077985e-5
GO:0015937	coenzyme A biosynthetic process	4.157638e-5
GO:0050779	RNA destabilization	4.260013e-5
GO:0002028	regulation of sodium ion transport	4.286144e-5
GO:0043624	cellular protein complex disassembly	4.337657e-5
GO:0042273	ribosomal large subunit biogenesis	4.750257e-5
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	4.750257e-5
GO:0043983	histone H4-K12 acetylation	4.838410e-5
GO:0006972	hyperosmotic response	4.863686e-5
GO:0051764	actin crosslink formation	4.878252e-5
GO:0048845	venous blood vessel morphogenesis	5.011356e-5
GO:0001826	inner cell mass cell differentiation	5.108145e-5
GO:0071391	cellular response to estrogen stimulus	5.207276e-5
GO:0002577	regulation of antigen processing and presentation	5.495106e-5
GO:0045345	positive regulation of MHC class I biosynthetic process	5.513433e-5
GO:0007398	ectoderm development	5.617660e-5
GO:0018993	somatic sex determination	5.844159e-5
GO:0035104	positive regulation of transcription via sterol regulatory element binding	5.926486e-5
GO:0032202	telomere assembly	5.938056e-5
GO:0070633	transepithelial transport	6.048777e-5
GO:0051135	positive regulation of NK T cell activation	6.273283e-5
GO:0043982	histone H4-K8 acetylation	6.653817e-5
GO:0043981	histone H4-K5 acetylation	6.653817e-5
GO:0051030	snRNA transport	6.745725e-5
GO:0045820	negative regulation of glycolysis	6.820732e-5
GO:0072593	reactive oxygen species metabolic process	6.998535e-5
GO:0001768	establishment of T cell polarity	7.500459e-5
GO:0060419	heart growth	7.564753e-5
GO:0007163	establishment or maintenance of cell polarity	8.365469e-5
GO:0050764	regulation of phagocytosis	8.997438e-5
GO:0033559	unsaturated fatty acid metabolic process	9.210415e-5
GO:0033700	phospholipid efflux	9.311234e-5
GO:0010624	regulation of Schwann cell proliferation	9.659761e-5
GO:0019062	virion attachment to host cell surface receptor	1.003757e-4
GO:0045059	positive thymic T cell selection	1.078624e-4
GO:0022415	viral reproductive process	1.079404e-4
GO:0014807	regulation of somitogenesis	1.081934e-4
GO:0034198	cellular response to amino acid starvation	1.180075e-4
GO:0034330	cell junction organization	1.323467e-4
GO:0032637	interleukin-8 production	1.380376e-4
GO:0046314	phosphocreatine biosynthetic process	1.424675e-4
GO:0048486	parasympathetic nervous system development	1.425720e-4
GO:0022411	cellular component disassembly	1.491898e-4
GO:0006690	icosanoid metabolic process	1.518222e-4
GO:0030853	negative regulation of granulocyte differentiation	1.539043e-4
GO:0055017	cardiac muscle tissue growth	1.544537e-4
GO:0050774	negative regulation of dendrite morphogenesis	1.595833e-4
GO:0045575	basophil activation	1.598033e-4
GO:0001694	histamine biosynthetic process	1.598033e-4
GO:0050862	positive regulation of T cell receptor signaling pathway	1.618337e-4
GO:0007296	vitellogenesis	1.698830e-4
GO:0003229	ventricular cardiac muscle tissue development	1.721175e-4
GO:0008610	lipid biosynthetic process	1.762157e-4
GO:0002367	cytokine production involved in immune response	1.790201e-4
GO:0001886	endothelial cell morphogenesis	1.805345e-4
GO:2000188	regulation of cholesterol homeostasis	2.027056e-4
GO:0000022	mitotic spindle elongation	2.027056e-4
GO:0010923	negative regulation of phosphatase activity	2.098389e-4
GO:0001692	histamine metabolic process	2.104028e-4
GO:0060706	cell differentiation involved in embryonic placenta development	2.132752e-4
GO:0065002	intracellular protein transmembrane transport	2.204616e-4
GO:0045908	negative regulation of vasodilation	2.249555e-4
GO:0018277	protein deamination	2.292138e-4
GO:0060177	regulation of angiotensin metabolic process	2.475145e-4
GO:0045061	thymic T cell selection	2.488843e-4
GO:0008643	carbohydrate transport	2.659493e-4
GO:0002579	positive regulation of antigen processing and presentation	2.697036e-4
GO:0032319	regulation of Rho GTPase activity	2.724867e-4
GO:0034616	response to laminar fluid shear stress	2.774869e-4
GO:0070574	cadmium ion transmembrane transport	2.909381e-4
GO:0045343	regulation of MHC class I biosynthetic process	3.007510e-4
GO:0002019	regulation of renal output by angiotensin	3.048504e-4
GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	3.074470e-4
GO:0001771	immunological synapse formation	3.159877e-4
GO:0032312	regulation of ARF GTPase activity	3.359215e-4
GO:0033209	tumor necrosis factor-mediated signaling pathway	3.359215e-4
GO:0042776	mitochondrial ATP synthesis coupled proton transport	3.399123e-4
GO:0003032	detection of oxygen	3.481487e-4
GO:0051973	positive regulation of telomerase activity	3.490582e-4
GO:0007028	cytoplasm organization	3.568326e-4
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	3.568326e-4
GO:0051937	catecholamine transport	3.575711e-4
GO:0030488	tRNA methylation	3.748510e-4
GO:0031508	centromeric heterochromatin formation	3.791950e-4
GO:0022601	menstrual cycle phase	3.817086e-4
GO:0051293	establishment of spindle localization	3.927918e-4
GO:0007195	inhibition of adenylate cyclase activity by dopamine receptor signaling pathway	3.957226e-4
GO:0060381	positive regulation of single-stranded telomeric DNA binding	4.039103e-4
GO:0071845	cellular component disassembly at cellular level	4.078474e-4
GO:0007051	spindle organization	4.123847e-4
GO:0007020	microtubule nucleation	4.192644e-4
GO:0042506	tyrosine phosphorylation of Stat5 protein	4.426511e-4
GO:0050766	positive regulation of phagocytosis	4.568225e-4
GO:0042320	regulation of circadian sleep/wake cycle, REM sleep	4.866994e-4
GO:0035357	peroxisome proliferator activated receptor signaling pathway	5.071282e-4
GO:0015760	glucose-6-phosphate transport	5.071282e-4
GO:0032984	macromolecular complex disassembly	5.274639e-4
GO:0085020	protein K6-linked ubiquitination	5.302893e-4
GO:0033002	muscle cell proliferation	5.582210e-4
GO:0021846	cell proliferation in forebrain	5.818480e-4
GO:0048532	anatomical structure arrangement	5.934077e-4
GO:0006014	D-ribose metabolic process	6.286276e-4
GO:0044154	histone H3-K14 acetylation	6.314544e-4
GO:0090086	negative regulation of protein deubiquitination	6.491603e-4
GO:0007161	calcium-independent cell-matrix adhesion	6.601978e-4
GO:0046730	induction of host immune response by virus	6.820695e-4
GO:0042487	regulation of odontogenesis of dentine-containing tooth	6.820695e-4
GO:0044240	multicellular organismal lipid catabolic process	6.853516e-4
GO:0060038	cardiac muscle cell proliferation	7.142753e-4
GO:0045651	positive regulation of macrophage differentiation	7.176119e-4
GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	7.319572e-4
GO:0006032	chitin catabolic process	7.320696e-4
GO:0044062	regulation of excretion	7.360065e-4
GO:0002540	leukotriene production involved in inflammatory response	7.503691e-4
GO:0090085	regulation of protein deubiquitination	7.660797e-4
GO:0035419	activation of MAPK activity involved in innate immune response	7.660797e-4
GO:0010763	positive regulation of fibroblast migration	7.741649e-4
GO:0061028	establishment of endothelial barrier	7.756605e-4
GO:0021984	adenohypophysis development	7.812472e-4
GO:0042552	myelination	7.832854e-4
GO:0045217	cell-cell junction maintenance	7.856768e-4
GO:0006909	phagocytosis	7.962941e-4
GO:0051323	metaphase	8.249577e-4
GO:0007000	nucleolus organization	8.254008e-4
GO:0018198	peptidyl-cysteine modification	8.649695e-4
GO:0050798	activated T cell proliferation	8.719759e-4
GO:0030336	negative regulation of cell migration	8.812085e-4
GO:0019228	regulation of action potential in neuron	8.861199e-4
GO:0006013	mannose metabolic process	8.999520e-4
GO:0033119	negative regulation of RNA splicing	9.143508e-4
GO:0007522	visceral muscle development	9.158792e-4
GO:0009226	nucleotide-sugar biosynthetic process	9.425222e-4
GO:0030382	sperm mitochondrion organization	9.473061e-4
GO:0030174	regulation of DNA-dependent DNA replication initiation	9.473061e-4
GO:0060251	regulation of glial cell proliferation	9.501420e-4
GO:2000465	regulation of glycogen (starch) synthase activity	9.521173e-4
GO:0015684	ferrous iron transport	9.632585e-4
GO:0043534	blood vessel endothelial cell migration	9.671926e-4
GO:0071956	cellular component maintenance at cellular level	9.697441e-4
GO:0007143	female meiosis	9.746791e-4
GO:0045218	zonula adherens maintenance	9.776895e-4
GO:0006090	pyruvate metabolic process	9.797500e-4
GO:0071281	cellular response to iron ion	9.954951e-4
GO:0006026	aminoglycan catabolic process	1.006694e-3
GO:0010631	epithelial cell migration	1.007737e-3
GO:0001300	chronological cell aging	1.030020e-3
GO:0031627	telomeric loop formation	1.103452e-3
GO:0042407	cristae formation	1.103452e-3
GO:0031529	ruffle organization	1.114781e-3
GO:0003073	regulation of systemic arterial blood pressure	1.117706e-3
GO:0002523	leukocyte migration involved in inflammatory response	1.121038e-3
GO:0060124	positive regulation of growth hormone secretion	1.121314e-3
GO:0005993	trehalose catabolic process	1.123854e-3
GO:0015872	dopamine transport	1.132643e-3
GO:0060707	trophoblast giant cell differentiation	1.139113e-3
GO:0043537	negative regulation of blood vessel endothelial cell migration	1.166010e-3
GO:0015853	adenine transport	1.183957e-3
GO:2000466	negative regulation of glycogen (starch) synthase activity	1.214416e-3
GO:0034776	response to histamine	1.226999e-3
GO:0015851	nucleobase transport	1.231802e-3
GO:0042396	phosphagen biosynthetic process	1.252724e-3
GO:0010985	negative regulation of lipoprotein particle clearance	1.254037e-3
GO:0060178	regulation of exocyst localization	1.290244e-3
GO:0001928	regulation of exocyst assembly	1.290244e-3
GO:0006408	snRNA export from nucleus	1.290244e-3
GO:0060134	prepulse inhibition	1.303218e-3
GO:0032241	positive regulation of nucleobase-containing compound transport	1.306210e-3
GO:0060218	hemopoietic stem cell differentiation	1.318441e-3
GO:0031365	N-terminal protein amino acid modification	1.320507e-3
GO:0015747	urate transport	1.346054e-3
GO:0061077	chaperone-mediated protein folding	1.360258e-3
GO:0032862	activation of Rho GTPase activity	1.377644e-3
GO:0070904	transepithelial L-ascorbic acid transport	1.389693e-3
GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter	1.394276e-3
GO:0000226	microtubule cytoskeleton organization	1.400743e-3
GO:2000209	regulation of anoikis	1.402312e-3
GO:0045943	positive regulation of transcription from RNA polymerase I promoter	1.410782e-3
GO:0048808	male genitalia morphogenesis	1.416979e-3
GO:0045604	regulation of epidermal cell differentiation	1.424345e-3
GO:0032964	collagen biosynthetic process	1.433262e-3
GO:0032717	negative regulation of interleukin-8 production	1.452109e-3
GO:0043001	Golgi to plasma membrane protein transport	1.459551e-3
GO:0051590	positive regulation of neurotransmitter transport	1.468661e-3
GO:0043089	positive regulation of Cdc42 GTPase activity	1.468661e-3
GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness	1.471701e-3
GO:0021783	preganglionic parasympathetic nervous system development	1.472615e-3
GO:0034014	response to triglyceride	1.519569e-3
GO:0009133	nucleoside diphosphate biosynthetic process	1.519569e-3
GO:0021623	oculomotor nerve formation	1.577650e-3
GO:0003404	optic vesicle morphogenesis	1.577650e-3
GO:0003409	optic cup structural organization	1.577650e-3
GO:0046950	cellular ketone body metabolic process	1.577804e-3
GO:0007197	inhibition of adenylate cyclase activity by muscarinic acetylcholine receptor signaling pathway	1.594039e-3
GO:0002016	regulation of blood volume by renin-angiotensin	1.625972e-3
GO:0044236	multicellular organismal metabolic process	1.643460e-3
GO:0010765	positive regulation of sodium ion transport	1.669381e-3
GO:0019693	ribose phosphate metabolic process	1.673606e-3
GO:0045616	regulation of keratinocyte differentiation	1.678607e-3
GO:0030260	entry into host cell	1.722055e-3
GO:0045542	positive regulation of cholesterol biosynthetic process	1.743030e-3
GO:0051004	regulation of lipoprotein lipase activity	1.746147e-3
GO:0006264	mitochondrial DNA replication	1.750838e-3
GO:0034959	endothelin maturation	1.770487e-3
GO:0010816	calcitonin catabolic process	1.770487e-3
GO:0010814	substance P catabolic process	1.770487e-3
GO:0032720	negative regulation of tumor necrosis factor production	1.776710e-3
GO:0007213	muscarinic acetylcholine receptor signaling pathway	1.810581e-3
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	1.822252e-3
GO:0032863	activation of Rac GTPase activity	1.822586e-3
GO:0072488	ammonium transmembrane transport	1.848090e-3
GO:0050704	regulation of interleukin-1 secretion	1.854734e-3
GO:0002005	angiotensin catabolic process in blood	1.857366e-3
GO:0034047	regulation of protein phosphatase type 2A activity	1.867051e-3
GO:0009992	cellular water homeostasis	1.867051e-3
GO:0003017	lymph circulation	1.867051e-3
GO:0034623	cellular macromolecular complex disassembly	1.894054e-3
GO:0050711	negative regulation of interleukin-1 secretion	1.923859e-3
GO:0046951	ketone body biosynthetic process	1.923859e-3
GO:0043314	negative regulation of neutrophil degranulation	1.937386e-3
GO:0042755	eating behavior	1.951495e-3
GO:0033865	nucleoside bisphosphate metabolic process	1.952841e-3
GO:0051918	negative regulation of fibrinolysis	1.967364e-3
GO:0043171	peptide catabolic process	1.975731e-3
GO:0032042	mitochondrial DNA metabolic process	1.986668e-3
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	1.988542e-3
GO:0032204	regulation of telomere maintenance	2.026788e-3
GO:0043249	erythrocyte maturation	2.094093e-3
GO:0042147	retrograde transport, endosome to Golgi	2.100041e-3
GO:0030302	deoxynucleotide transport	2.112408e-3
GO:0032364	oxygen homeostasis	2.146981e-3
GO:0000244	assembly of spliceosomal tri-snRNP	2.195380e-3
GO:0035813	regulation of renal sodium excretion	2.195463e-3
GO:2000573	positive regulation of DNA biosynthetic process	2.207791e-3
GO:0030037	actin filament reorganization involved in cell cycle	2.222101e-3
GO:0001916	positive regulation of T cell mediated cytotoxicity	2.244833e-3
GO:0044058	regulation of digestive system process	2.265438e-3
GO:0090141	positive regulation of mitochondrial fission	2.307338e-3
GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep	2.307628e-3
GO:0051152	positive regulation of smooth muscle cell differentiation	2.312009e-3
GO:0006682	galactosylceramide biosynthetic process	2.368608e-3
GO:0034766	negative regulation of ion transmembrane transport	2.368608e-3
GO:0048266	behavioral response to pain	2.391105e-3
GO:0060252	positive regulation of glial cell proliferation	2.394506e-3
GO:0010873	positive regulation of cholesterol esterification	2.394506e-3
GO:0000132	establishment of mitotic spindle orientation	2.408564e-3
GO:0055009	atrial cardiac muscle tissue morphogenesis	2.410612e-3
GO:0060956	endocardial cell differentiation	2.425524e-3
GO:0010596	negative regulation of endothelial cell migration	2.456540e-3
GO:0034695	response to prostaglandin E stimulus	2.497498e-3
GO:0090162	establishment of epithelial cell polarity	2.522963e-3
GO:0051271	negative regulation of cellular component movement	2.602060e-3
GO:0030862	positive regulation of polarized epithelial cell differentiation	2.614483e-3
GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	2.614483e-3
GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	2.614483e-3
GO:0006021	inositol biosynthetic process	2.614483e-3
GO:0071955	recycling endosome to Golgi transport	2.627078e-3
GO:0034499	late endosome to Golgi transport	2.627078e-3
GO:0090136	epithelial cell-cell adhesion	2.630550e-3
GO:0015914	phospholipid transport	2.679467e-3
GO:0010984	regulation of lipoprotein particle clearance	2.689265e-3
GO:0000236	mitotic prometaphase	2.700612e-3
GO:0090205	positive regulation of cholesterol metabolic process	2.736861e-3
GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	2.814092e-3
GO:0045010	actin nucleation	2.825771e-3
GO:0033622	integrin activation	2.856009e-3
GO:0007321	sperm displacement	2.856009e-3
GO:0010735	positive regulation of transcription via serum response element binding	2.878316e-3
GO:0007144	female meiosis I	2.878316e-3
GO:0070307	lens fiber cell development	2.894548e-3
GO:0030953	astral microtubule organization	2.923029e-3
GO:0030321	transepithelial chloride transport	2.939717e-3
GO:0060267	positive regulation of respiratory burst	2.967978e-3
GO:0097150	neuronal stem cell maintenance	2.970771e-3
GO:0009817	defense response to fungus, incompatible interaction	3.066454e-3
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	3.066454e-3
GO:0090161	Golgi ribbon formation	3.066454e-3
GO:0048143	astrocyte activation	3.066454e-3
GO:0040001	establishment of mitotic spindle localization	3.066904e-3
GO:0008210	estrogen metabolic process	3.070185e-3
GO:0042048	olfactory behavior	3.100026e-3
GO:0021557	oculomotor nerve development	3.206082e-3
GO:0043462	regulation of ATPase activity	3.233718e-3
GO:0040015	negative regulation of multicellular organism growth	3.265240e-3
GO:0090031	positive regulation of steroid hormone biosynthetic process	3.279846e-3
GO:0043547	positive regulation of GTPase activity	3.349406e-3
GO:0009119	ribonucleoside metabolic process	3.406808e-3
GO:0043932	ossification involved in bone remodeling	3.424785e-3
GO:0006911	phagocytosis, engulfment	3.433215e-3
GO:0006481	C-terminal protein methylation	3.486380e-3
GO:0034259	negative regulation of Rho GTPase activity	3.502409e-3
GO:0019344	cysteine biosynthetic process	3.502409e-3
GO:0043542	endothelial cell migration	3.513124e-3
GO:0051561	elevation of mitochondrial calcium ion concentration	3.521176e-3
GO:0022009	central nervous system vasculogenesis	3.549951e-3
GO:0019367	fatty acid elongation, saturated fatty acid	3.568857e-3
GO:0000920	cytokinetic cell separation	3.568857e-3
GO:0045404	positive regulation of interleukin-4 biosynthetic process	3.572124e-3
GO:0042136	neurotransmitter biosynthetic process	3.626629e-3
GO:2000974	negative regulation of pro-B cell differentiation	3.661212e-3
GO:0006826	iron ion transport	3.669313e-3
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling	3.671302e-3
GO:0032376	positive regulation of cholesterol transport	3.675125e-3
GO:0006891	intra-Golgi vesicle-mediated transport	3.781487e-3
GO:0035264	multicellular organism growth	3.823920e-3
GO:0051917	regulation of fibrinolysis	3.835764e-3
GO:0032914	positive regulation of transforming growth factor beta1 production	3.839674e-3
GO:0048194	Golgi vesicle budding	3.937374e-3
GO:0006140	regulation of nucleotide metabolic process	3.944840e-3
GO:0001990	regulation of systemic arterial blood pressure by hormone	3.949629e-3
GO:0010755	regulation of plasminogen activation	3.949629e-3
GO:0006656	phosphatidylcholine biosynthetic process	3.965667e-3
GO:0018026	peptidyl-lysine monomethylation	3.969927e-3
GO:0042508	tyrosine phosphorylation of Stat1 protein	3.987602e-3
GO:0044268	multicellular organismal protein metabolic process	4.005776e-3
GO:0006172	ADP biosynthetic process	4.005776e-3
GO:0032980	keratinocyte activation	4.055383e-3
GO:0010756	positive regulation of plasminogen activation	4.055383e-3
GO:0046833	positive regulation of RNA export from nucleus	4.088026e-3
GO:0090007	regulation of mitotic anaphase	4.088026e-3
GO:0008645	hexose transport	4.140820e-3
GO:0035305	negative regulation of dephosphorylation	4.159939e-3
GO:0032632	interleukin-3 production	4.174644e-3
GO:0045342	MHC class II biosynthetic process	4.174644e-3
GO:0070839	divalent metal ion export	4.174644e-3
GO:0043091	L-arginine import	4.174644e-3
GO:0006876	cellular cadmium ion homeostasis	4.174644e-3
GO:0015707	nitrite transport	4.174644e-3
GO:0032226	positive regulation of synaptic transmission, dopaminergic	4.174644e-3
GO:0060482	lobar bronchus development	4.232691e-3
GO:0006420	arginyl-tRNA aminoacylation	4.247154e-3
GO:2000077	negative regulation of type B pancreatic cell development	4.247154e-3
GO:0032098	regulation of appetite	4.280197e-3
GO:0046339	diacylglycerol metabolic process	4.332097e-3
GO:0033121	regulation of purine nucleotide catabolic process	4.346276e-3
GO:0010936	negative regulation of macrophage cytokine production	4.359872e-3
GO:0034260	negative regulation of GTPase activity	4.383517e-3
GO:0046513	ceramide biosynthetic process	4.418277e-3
GO:0031848	protection from non-homologous end joining at telomere	4.420493e-3
GO:0048144	fibroblast proliferation	4.420493e-3
GO:0000301	retrograde transport, vesicle recycling within Golgi	4.458387e-3
GO:0015844	monoamine transport	4.485553e-3
GO:0019321	pentose metabolic process	4.507823e-3
GO:0045402	regulation of interleukin-4 biosynthetic process	4.522550e-3
GO:0015749	monosaccharide transport	4.536773e-3
GO:0043313	regulation of neutrophil degranulation	4.560067e-3
GO:0051895	negative regulation of focal adhesion assembly	4.624713e-3
GO:0000089	mitotic metaphase	4.628458e-3
GO:0046101	hypoxanthine biosynthetic process	4.644380e-3
GO:0002513	tolerance induction to self antigen	4.644380e-3
GO:0034115	negative regulation of heterotypic cell-cell adhesion	4.651945e-3
GO:0010742	macrophage derived foam cell differentiation	4.651945e-3
GO:0001516	prostaglandin biosynthetic process	4.657991e-3
GO:0010875	positive regulation of cholesterol efflux	4.727783e-3
GO:0010954	positive regulation of protein processing	4.866685e-3
GO:0016032	viral reproduction	4.882626e-3
GO:0009298	GDP-mannose biosynthetic process	4.889737e-3
GO:0055072	iron ion homeostasis	4.896195e-3
GO:0045655	regulation of monocyte differentiation	4.916561e-3
GO:0001964	startle response	4.968679e-3
GO:0006385	transcription elongation from RNA polymerase III promoter	5.001409e-3
GO:0006386	termination of RNA polymerase III transcription	5.001409e-3
GO:0071816	tail-anchored membrane protein insertion into ER membrane	5.004941e-3
GO:0010919	regulation of inositol phosphate biosynthetic process	5.051818e-3
GO:0010039	response to iron ion	5.058241e-3
GO:0044254	multicellular organismal protein catabolic process	5.070872e-3
GO:0002067	glandular epithelial cell differentiation	5.128437e-3
GO:0001836	release of cytochrome c from mitochondria	5.166336e-3
GO:0051788	response to misfolded protein	5.224124e-3
GO:0072060	outer medullary collecting duct development	5.268581e-3
GO:0072061	inner medullary collecting duct development	5.268581e-3
GO:0016332	establishment or maintenance of polarity of embryonic epithelium	5.268581e-3
GO:0006600	creatine metabolic process	5.271759e-3
GO:0006200	ATP catabolic process	5.294488e-3
GO:0046687	response to chromate	5.328870e-3
GO:0033986	response to methanol	5.328870e-3
GO:0006879	cellular iron ion homeostasis	5.335451e-3
GO:0033962	cytoplasmic mRNA processing body assembly	5.378625e-3
GO:0042730	fibrinolysis	5.432575e-3
GO:0051584	regulation of dopamine uptake	5.432832e-3
GO:0006693	prostaglandin metabolic process	5.460622e-3
GO:0070120	ciliary neurotrophic factor-mediated signaling pathway	5.518368e-3
GO:0031284	positive regulation of guanylate cyclase activity	5.520025e-3
GO:0060370	susceptibility to T cell mediated cytotoxicity	5.530037e-3
GO:0042503	tyrosine phosphorylation of Stat3 protein	5.540176e-3
GO:0048873	homeostasis of number of cells within a tissue	5.638914e-3
GO:0007260	tyrosine phosphorylation of STAT protein	5.700442e-3
GO:0021849	neuroblast division in subventricular zone	5.712480e-3
GO:0045955	negative regulation of calcium ion-dependent exocytosis	5.802339e-3
GO:0045039	protein import into mitochondrial inner membrane	5.812583e-3
GO:0042321	negative regulation of circadian sleep/wake cycle, sleep	5.812583e-3
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	5.937652e-3
GO:0080009	mRNA methylation	5.940166e-3
GO:2000781	positive regulation of double-strand break repair	5.940166e-3
GO:0042747	circadian sleep/wake cycle, REM sleep	5.940166e-3
GO:0045212	neurotransmitter receptor biosynthetic process	5.940166e-3
GO:0032223	negative regulation of synaptic transmission, cholinergic	5.940166e-3
GO:0010523	negative regulation of calcium ion transport into cytosol	6.035985e-3
GO:0046731	passive induction of host immune response by virus	6.083848e-3
GO:0034314	Arp2/3 complex-mediated actin nucleation	6.083848e-3
GO:0051220	cytoplasmic sequestering of protein	6.194453e-3
GO:0072332	signal transduction by p53 class mediator resulting in induction of apoptosis	6.232398e-3
GO:0006667	sphinganine metabolic process	6.376188e-3
GO:0001766	membrane raft polarization	6.376188e-3
GO:0001845	phagolysosome assembly	6.376188e-3
GO:0007386	compartment pattern specification	6.381041e-3
GO:0003417	growth plate cartilage development	6.381041e-3
GO:2000146	negative regulation of cell motility	6.382148e-3
GO:0051056	regulation of small GTPase mediated signal transduction	6.429508e-3
GO:0045109	intermediate filament organization	6.618388e-3
GO:0019883	antigen processing and presentation of endogenous antigen	6.623396e-3
GO:0003157	endocardium development	6.695859e-3
GO:0070613	regulation of protein processing	6.717914e-3
GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	6.746984e-3
GO:0030579	ubiquitin-dependent SMAD protein catabolic process	6.761062e-3
GO:0070947	neutrophil mediated killing of fungus	6.828005e-3
GO:0060876	semicircular canal formation	6.828005e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0046031	ADP metabolic process	2.270343e-9
GO:0002444	myeloid leukocyte mediated immunity	3.219803e-8
GO:0009179	purine ribonucleoside diphosphate metabolic process	1.263790e-7
GO:0043303	mast cell degranulation	2.286996e-7
GO:0045104	intermediate filament cytoskeleton organization	7.597972e-7
GO:0045055	regulated secretory pathway	1.162500e-6
GO:0045542	positive regulation of cholesterol biosynthetic process	1.276933e-6
GO:0045103	intermediate filament-based process	1.863743e-6
GO:0043299	leukocyte degranulation	1.873844e-6
GO:0046709	IDP catabolic process	1.935412e-6
GO:0046032	ADP catabolic process	1.935412e-6
GO:0032682	negative regulation of chemokine production	3.417704e-6
GO:0006360	transcription from RNA polymerase I promoter	3.570943e-6
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	4.334531e-6
GO:0032856	activation of Ras GTPase activity	4.461206e-6
GO:2000466	negative regulation of glycogen (starch) synthase activity	5.469817e-6
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	6.992437e-6
GO:0006172	ADP biosynthetic process	7.026193e-6
GO:0043094	cellular metabolic compound salvage	7.236491e-6
GO:0070198	protein localization to chromosome, telomeric region	7.725117e-6
GO:0045453	bone resorption	9.256529e-6
GO:0031331	positive regulation of cellular catabolic process	1.018263e-5
GO:0006644	phospholipid metabolic process	1.057622e-5
GO:0090074	negative regulation of protein homodimerization activity	1.067151e-5
GO:0042554	superoxide anion generation	1.101737e-5
GO:0045796	negative regulation of intestinal cholesterol absorption	1.267519e-5
GO:0010949	negative regulation of intestinal phytosterol absorption	1.267519e-5
GO:0061077	chaperone-mediated protein folding	1.360390e-5
GO:0060457	negative regulation of digestive system process	1.396873e-5
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	1.452500e-5
GO:0006887	exocytosis	1.626248e-5
GO:0006629	lipid metabolic process	1.890486e-5
GO:0071702	organic substance transport	1.973441e-5
GO:0031329	regulation of cellular catabolic process	2.058706e-5
GO:0046501	protoporphyrinogen IX metabolic process	2.074428e-5
GO:0032206	positive regulation of telomere maintenance	2.074428e-5
GO:0043089	positive regulation of Cdc42 GTPase activity	2.304905e-5
GO:0044255	cellular lipid metabolic process	2.568318e-5
GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	2.570052e-5
GO:0051127	positive regulation of actin nucleation	2.701525e-5
GO:0048002	antigen processing and presentation of peptide antigen	2.739376e-5
GO:0045576	mast cell activation	2.916093e-5
GO:0019882	antigen processing and presentation	2.965900e-5
GO:0009894	regulation of catabolic process	3.167812e-5
GO:0009185	ribonucleoside diphosphate metabolic process	3.633175e-5
GO:0033504	floor plate development	4.087048e-5
GO:0032862	activation of Rho GTPase activity	4.273444e-5
GO:0048050	post-embryonic eye morphogenesis	4.429491e-5
GO:0035441	cell migration involved in vasculogenesis	4.942115e-5
GO:0035021	negative regulation of Rac protein signal transduction	4.942115e-5
GO:0015758	glucose transport	5.190843e-5
GO:0032863	activation of Rac GTPase activity	5.233570e-5
GO:0009132	nucleoside diphosphate metabolic process	5.440725e-5
GO:0042168	heme metabolic process	5.449109e-5
GO:0008645	hexose transport	5.648614e-5
GO:0002642	positive regulation of immunoglobulin biosynthetic process	5.651322e-5
GO:0051345	positive regulation of hydrolase activity	6.092997e-5
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	7.821588e-5
GO:0010717	regulation of epithelial to mesenchymal transition	7.825664e-5
GO:0061014	positive regulation of mRNA catabolic process	7.989893e-5
GO:0042440	pigment metabolic process	8.480433e-5
GO:0090084	negative regulation of inclusion body assembly	8.617580e-5
GO:0009051	pentose-phosphate shunt, oxidative branch	8.789611e-5
GO:0070050	neuron homeostasis	9.245077e-5
GO:0046889	positive regulation of lipid biosynthetic process	9.283898e-5
GO:0015914	phospholipid transport	9.398402e-5
GO:0015749	monosaccharide transport	9.401960e-5
GO:0071715	icosanoid transport	9.671878e-5
GO:0009161	ribonucleoside monophosphate metabolic process	9.959874e-5
GO:0050482	arachidonic acid secretion	1.024817e-4
GO:0009220	pyrimidine ribonucleotide biosynthetic process	1.198272e-4
GO:0000303	response to superoxide	1.230001e-4
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	1.266560e-4
GO:0007440	foregut morphogenesis	1.270707e-4
GO:0008643	carbohydrate transport	1.366720e-4
GO:0007340	acrosome reaction	1.399975e-4
GO:0060052	neurofilament cytoskeleton organization	1.417636e-4
GO:2000116	regulation of cysteine-type endopeptidase activity	1.473163e-4
GO:0090086	negative regulation of protein deubiquitination	1.485593e-4
GO:0009260	ribonucleotide biosynthetic process	1.487493e-4
GO:0043096	purine base salvage	1.524883e-4
GO:0002274	myeloid leukocyte activation	1.532854e-4
GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter	1.601504e-4
GO:0048102	autophagic cell death	1.601504e-4
GO:0032287	peripheral nervous system myelin maintenance	1.601504e-4
GO:0033137	negative regulation of peptidyl-serine phosphorylation	1.608177e-4
GO:0019637	organophosphate metabolic process	1.610754e-4
GO:0001824	blastocyst development	1.622867e-4
GO:0009181	purine ribonucleoside diphosphate catabolic process	1.651046e-4
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	1.676954e-4
GO:0043088	regulation of Cdc42 GTPase activity	1.687830e-4
GO:0031648	protein destabilization	1.742343e-4
GO:0031558	induction of apoptosis in response to chemical stimulus	1.771707e-4
GO:0009156	ribonucleoside monophosphate biosynthetic process	1.829528e-4
GO:0032859	activation of Ral GTPase activity	1.965881e-4
GO:0060828	regulation of canonical Wnt receptor signaling pathway	2.073322e-4
GO:0071956	cellular component maintenance at cellular level	2.107891e-4
GO:0009896	positive regulation of catabolic process	2.239300e-4
GO:0006801	superoxide metabolic process	2.242199e-4
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	2.401004e-4
GO:0006997	nucleus organization	2.404339e-4
GO:0031442	positive regulation of mRNA 3'-end processing	2.444380e-4
GO:0046148	pigment biosynthetic process	2.554973e-4
GO:0070059	apoptosis in response to endoplasmic reticulum stress	2.577147e-4
GO:0060662	salivary gland cavitation	2.617254e-4
GO:0046483	heterocycle metabolic process	2.623120e-4
GO:0061013	regulation of mRNA catabolic process	2.627673e-4
GO:0060458	right lung development	2.680130e-4
GO:0048597	post-embryonic camera-type eye morphogenesis	2.680130e-4
GO:0022601	menstrual cycle phase	2.701222e-4
GO:0046903	secretion	2.717124e-4
GO:0033089	positive regulation of T cell differentiation in thymus	2.753298e-4
GO:0071034	CUT catabolic process	2.835297e-4
GO:0007352	zygotic specification of dorsal/ventral axis	2.896257e-4
GO:0035691	macrophage migration inhibitory factor signaling pathway	2.896257e-4
GO:0070842	aggresome assembly	2.919599e-4
GO:0033505	floor plate morphogenesis	2.919599e-4
GO:0009119	ribonucleoside metabolic process	3.002291e-4
GO:0042538	hyperosmotic salinity response	3.094617e-4
GO:0002478	antigen processing and presentation of exogenous peptide antigen	3.125786e-4
GO:0045880	positive regulation of smoothened signaling pathway	3.136938e-4
GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development	3.187591e-4
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	3.275906e-4
GO:0050701	interleukin-1 secretion	3.285386e-4
GO:0010900	negative regulation of phosphatidylcholine catabolic process	3.285386e-4
GO:0032940	secretion by cell	3.320172e-4
GO:0060014	granulosa cell differentiation	3.459270e-4
GO:0045620	negative regulation of lymphocyte differentiation	3.525925e-4
GO:0006003	fructose 2,6-bisphosphate metabolic process	3.544823e-4
GO:0042274	ribosomal small subunit biogenesis	3.677012e-4
GO:0048617	embryonic foregut morphogenesis	3.686912e-4
GO:0009218	pyrimidine ribonucleotide metabolic process	3.686912e-4
GO:0010660	regulation of muscle cell apoptosis	3.822097e-4
GO:0015884	folic acid transport	3.937830e-4
GO:0090083	regulation of inclusion body assembly	3.937830e-4
GO:0071529	cementum mineralization	4.066860e-4
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	4.093589e-4
GO:0009112	nucleobase metabolic process	4.366708e-4
GO:0070212	protein poly-ADP-ribosylation	4.486756e-4
GO:0032212	positive regulation of telomere maintenance via telomerase	4.486756e-4
GO:0032928	regulation of superoxide anion generation	4.532730e-4
GO:0006778	porphyrin-containing compound metabolic process	4.556648e-4
GO:0030111	regulation of Wnt receptor signaling pathway	4.581793e-4
GO:0046456	icosanoid biosynthetic process	4.588028e-4
GO:0042345	regulation of NF-kappaB import into nucleus	4.621749e-4
GO:0071407	cellular response to organic cyclic compound	4.775058e-4
GO:0033007	negative regulation of mast cell activation involved in immune response	4.791860e-4
GO:0072593	reactive oxygen species metabolic process	4.825322e-4
GO:0002830	positive regulation of type 2 immune response	5.054136e-4
GO:2000249	regulation of actin cytoskeleton reorganization	5.130938e-4
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB cascade	5.158125e-4
GO:0006690	icosanoid metabolic process	5.185290e-4
GO:0006869	lipid transport	5.358713e-4
GO:0046112	nucleobase biosynthetic process	5.383972e-4
GO:0003273	cell migration involved in endocardial cushion formation	5.437607e-4
GO:0071392	cellular response to estradiol stimulus	5.443548e-4
GO:0043103	hypoxanthine salvage	5.516240e-4
GO:0032261	purine nucleotide salvage	5.516240e-4
GO:0019835	cytolysis	5.564940e-4
GO:0045089	positive regulation of innate immune response	5.596267e-4
GO:0019430	removal of superoxide radicals	5.679356e-4
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	5.766441e-4
GO:0010719	negative regulation of epithelial to mesenchymal transition	5.980299e-4
GO:0033013	tetrapyrrole metabolic process	6.118202e-4
GO:0032612	interleukin-1 production	6.366016e-4
GO:0007422	peripheral nervous system development	6.551656e-4
GO:0030177	positive regulation of Wnt receptor signaling pathway	6.559422e-4
GO:0032365	intracellular lipid transport	6.566710e-4
GO:0060711	labyrinthine layer development	6.605772e-4
GO:0033687	osteoblast proliferation	6.643082e-4
GO:0060696	regulation of phospholipid catabolic process	6.643082e-4
GO:0008333	endosome to lysosome transport	6.659395e-4
GO:0051299	centrosome separation	6.916038e-4
GO:0072528	pyrimidine-containing compound biosynthetic process	6.945769e-4
GO:0042574	retinal metabolic process	7.325930e-4
GO:0046655	folic acid metabolic process	7.866211e-4
GO:0006783	heme biosynthetic process	7.883854e-4
GO:0000305	response to oxygen radical	7.923403e-4
GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation	8.084417e-4
GO:0070166	enamel mineralization	8.096193e-4
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	8.330090e-4
GO:0071257	cellular response to electrical stimulus	8.442939e-4
GO:0071248	cellular response to metal ion	8.475720e-4
GO:0031081	nuclear pore distribution	8.876304e-4
GO:0006222	UMP biosynthetic process	8.957036e-4
GO:0045732	positive regulation of protein catabolic process	9.131102e-4
GO:0022411	cellular component disassembly	9.163343e-4
GO:0042993	positive regulation of transcription factor import into nucleus	9.169868e-4
GO:0071593	lymphocyte aggregation	9.213870e-4
GO:0010761	fibroblast migration	9.408310e-4
GO:0046849	bone remodeling	9.717232e-4
GO:0009133	nucleoside diphosphate biosynthetic process	9.825515e-4
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	9.825515e-4
GO:0018130	heterocycle biosynthetic process	9.935133e-4
GO:0070213	protein auto-ADP-ribosylation	1.003372e-3
GO:0003420	regulation of growth plate cartilage chondrocyte proliferation	1.003372e-3
GO:0046210	nitric oxide catabolic process	1.014076e-3
GO:0090346	cellular organofluorine metabolic process	1.014076e-3
GO:0043602	nitrate catabolic process	1.014076e-3
GO:0006782	protoporphyrinogen IX biosynthetic process	1.014076e-3
GO:0001832	blastocyst growth	1.018529e-3
GO:0006144	purine base metabolic process	1.023671e-3
GO:0007274	neuromuscular synaptic transmission	1.033101e-3
GO:0015992	proton transport	1.056616e-3
GO:0002366	leukocyte activation involved in immune response	1.068353e-3
GO:0006818	hydrogen transport	1.068660e-3
GO:0015986	ATP synthesis coupled proton transport	1.080571e-3
GO:0060463	lung lobe morphogenesis	1.083890e-3
GO:0006702	androgen biosynthetic process	1.105127e-3
GO:0015876	acetyl-CoA transport	1.153150e-3
GO:0043173	nucleotide salvage	1.166377e-3
GO:0042346	positive regulation of NF-kappaB import into nucleus	1.175374e-3
GO:0006636	unsaturated fatty acid biosynthetic process	1.210088e-3
GO:0043616	keratinocyte proliferation	1.215986e-3
GO:0051297	centrosome organization	1.223737e-3
GO:0051546	keratinocyte migration	1.238486e-3
GO:0032463	negative regulation of protein homooligomerization	1.245702e-3
GO:0045217	cell-cell junction maintenance	1.245702e-3
GO:0015816	glycine transport	1.245702e-3
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	1.247317e-3
GO:0006650	glycerophospholipid metabolic process	1.250864e-3
GO:0019884	antigen processing and presentation of exogenous antigen	1.280841e-3
GO:0050927	positive regulation of positive chemotaxis	1.289246e-3
GO:0016075	rRNA catabolic process	1.298519e-3
GO:0008654	phospholipid biosynthetic process	1.346350e-3
GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.359120e-3
GO:0051125	regulation of actin nucleation	1.376444e-3
GO:0043101	purine-containing compound salvage	1.376444e-3
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	1.389816e-3
GO:0042891	antibiotic transport	1.389816e-3
GO:0042509	regulation of tyrosine phosphorylation of STAT protein	1.393156e-3
GO:0043392	negative regulation of DNA binding	1.422943e-3
GO:0002275	myeloid cell activation involved in immune response	1.436277e-3
GO:0042743	hydrogen peroxide metabolic process	1.509564e-3
GO:0048808	male genitalia morphogenesis	1.559515e-3
GO:0071845	cellular component disassembly at cellular level	1.571493e-3
GO:0009306	protein secretion	1.574531e-3
GO:0042662	negative regulation of mesodermal cell fate specification	1.587060e-3
GO:0055010	ventricular cardiac muscle tissue morphogenesis	1.591074e-3
GO:2000737	negative regulation of stem cell differentiation	1.616683e-3
GO:0002352	B cell negative selection	1.616683e-3
GO:0034391	regulation of smooth muscle cell apoptosis	1.694488e-3
GO:0033121	regulation of purine nucleotide catabolic process	1.695953e-3
GO:0051602	response to electrical stimulus	1.705908e-3
GO:0006779	porphyrin-containing compound biosynthetic process	1.714653e-3
GO:0071285	cellular response to lithium ion	1.719187e-3
GO:2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.719187e-3
GO:0051725	protein de-ADP-ribosylation	1.746914e-3
GO:0034661	ncRNA catabolic process	1.762809e-3
GO:0032864	activation of Cdc42 GTPase activity	1.771213e-3
GO:0045767	regulation of anti-apoptosis	1.782685e-3
GO:0035520	monoubiquitinated protein deubiquitination	1.810144e-3
GO:0009152	purine ribonucleotide biosynthetic process	1.813613e-3
GO:0016998	cell wall macromolecule catabolic process	1.820751e-3
GO:0031440	regulation of mRNA 3'-end processing	1.865371e-3
GO:0034505	tooth mineralization	1.870411e-3
GO:0044070	regulation of anion transport	1.890228e-3
GO:0048705	skeletal system morphogenesis	1.891536e-3
GO:0060716	labyrinthine layer blood vessel development	1.902187e-3
GO:0051668	localization within membrane	1.920879e-3
GO:0003032	detection of oxygen	1.928002e-3
GO:0052548	regulation of endopeptidase activity	1.932730e-3
GO:0033081	regulation of T cell differentiation in thymus	1.941659e-3
GO:0035966	response to topologically incorrect protein	2.038433e-3
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	2.066265e-3
GO:0034654	nucleobase-containing compound biosynthetic process	2.169717e-3
GO:0035725	sodium ion transmembrane transport	2.218485e-3
GO:0018202	peptidyl-histidine modification	2.220598e-3
GO:0046427	positive regulation of JAK-STAT cascade	2.222785e-3
GO:0032849	positive regulation of cellular pH reduction	2.280928e-3
GO:0014044	Schwann cell development	2.283447e-3
GO:0072088	nephron epithelium morphogenesis	2.315543e-3
GO:0032321	positive regulation of Rho GTPase activity	2.324598e-3
GO:0038003	opioid receptor signaling pathway	2.363933e-3
GO:0031848	protection from non-homologous end joining at telomere	2.363933e-3
GO:0032479	regulation of type I interferon production	2.416952e-3
GO:0008209	androgen metabolic process	2.430015e-3
GO:0009167	purine ribonucleoside monophosphate metabolic process	2.445018e-3
GO:0042703	menstruation	2.445456e-3
GO:0019101	female somatic sex determination	2.445456e-3
GO:0006258	UDP-glucose catabolic process	2.445456e-3
GO:0001579	medium-chain fatty acid transport	2.445456e-3
GO:0002443	leukocyte mediated immunity	2.445785e-3
GO:0010656	negative regulation of muscle cell apoptosis	2.466948e-3
GO:0009259	ribonucleotide metabolic process	2.514856e-3
GO:0051788	response to misfolded protein	2.541651e-3
GO:0006654	phosphatidic acid biosynthetic process	2.579058e-3
GO:0048859	formation of anatomical boundary	2.590698e-3
GO:0006657	CDP-choline pathway	2.592104e-3
GO:0070366	regulation of hepatocyte differentiation	2.597787e-3
GO:0060977	coronary vasculature morphogenesis	2.602454e-3
GO:0032984	macromolecular complex disassembly	2.616894e-3
GO:0002831	regulation of response to biotic stimulus	2.628782e-3
GO:0048148	behavioral response to cocaine	2.655925e-3
GO:0050926	regulation of positive chemotaxis	2.662890e-3
GO:0032319	regulation of Rho GTPase activity	2.735397e-3
GO:0001570	vasculogenesis	2.745171e-3
GO:0001833	inner cell mass cell proliferation	2.749791e-3
GO:0021508	floor plate formation	2.810364e-3
GO:0006168	adenine salvage	2.810364e-3
GO:0006000	fructose metabolic process	2.820130e-3
GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	2.837699e-3
GO:0071347	cellular response to interleukin-1	2.858267e-3
GO:0006691	leukotriene metabolic process	2.902012e-3
GO:0001649	osteoblast differentiation	2.927291e-3
GO:0007184	SMAD protein import into nucleus	2.943753e-3
GO:0048566	embryonic digestive tract development	3.001173e-3
GO:0002858	regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	3.036626e-3
GO:0043503	skeletal muscle fiber adaptation	3.050459e-3
GO:0006927	transformed cell apoptosis	3.050459e-3
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	3.061283e-3
GO:0033344	cholesterol efflux	3.063182e-3
GO:0030162	regulation of proteolysis	3.087503e-3
GO:0015760	glucose-6-phosphate transport	3.175114e-3
GO:0051085	chaperone mediated protein folding requiring cofactor	3.210554e-3
GO:0002828	regulation of type 2 immune response	3.225611e-3
GO:0002358	B cell homeostatic proliferation	3.227106e-3
GO:0021526	medial motor column neuron differentiation	3.235928e-3
GO:0043280	positive regulation of caspase activity	3.293300e-3
GO:0051591	response to cAMP	3.300949e-3
GO:0032418	lysosome localization	3.302544e-3
GO:0070245	positive regulation of thymocyte apoptosis	3.304916e-3
GO:0046686	response to cadmium ion	3.338868e-3
GO:0046037	GMP metabolic process	3.347106e-3
GO:0010952	positive regulation of peptidase activity	3.374130e-3
GO:0018230	peptidyl-L-cysteine S-palmitoylation	3.417324e-3
GO:0035623	renal glucose absorption	3.417324e-3
GO:0001775	cell activation	3.438283e-3
GO:0001516	prostaglandin biosynthetic process	3.457334e-3
GO:0003308	negative regulation of Wnt receptor signaling pathway involved in heart development	3.462068e-3
GO:0061056	sclerotome development	3.462068e-3
GO:0070234	positive regulation of T cell apoptosis	3.507214e-3
GO:0060806	negative regulation of cell differentiation involved in embryonic placenta development	3.521359e-3
GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine	3.521359e-3
GO:0006433	prolyl-tRNA aminoacylation	3.521359e-3
GO:0021940	positive regulation of cerebellar granule cell precursor proliferation	3.530671e-3
GO:0044093	positive regulation of molecular function	3.654547e-3
GO:0032481	positive regulation of type I interferon production	3.657558e-3
GO:0070933	histone H4 deacetylation	3.697745e-3
GO:0048147	negative regulation of fibroblast proliferation	3.705409e-3
GO:0017156	calcium ion-dependent exocytosis	3.722208e-3
GO:0006817	phosphate ion transport	3.727008e-3
GO:0009110	vitamin biosynthetic process	3.758993e-3
GO:0060710	chorio-allantoic fusion	3.777682e-3
GO:0045332	phospholipid translocation	3.791774e-3
GO:0007243	intracellular protein kinase cascade	3.792818e-3
GO:0032872	regulation of stress-activated MAPK cascade	3.942020e-3
GO:0045578	negative regulation of B cell differentiation	3.948516e-3
GO:0022011	myelination in peripheral nervous system	3.964415e-3
GO:0021936	regulation of cerebellar granule cell precursor proliferation	3.964415e-3
GO:0006685	sphingomyelin catabolic process	3.980690e-3
GO:0061370	testosterone biosynthetic process	3.980690e-3
GO:0003140	determination of left/right asymmetry in lateral mesoderm	3.980690e-3
GO:0006998	nuclear envelope organization	4.017015e-3
GO:0006207	'de novo' pyrimidine base biosynthetic process	4.056726e-3
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	4.056920e-3
GO:0010833	telomere maintenance via telomere lengthening	4.074140e-3
GO:0051482	elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger	4.074751e-3
GO:0006693	prostaglandin metabolic process	4.087776e-3
GO:0007254	JNK cascade	4.117376e-3
GO:0002036	regulation of L-glutamate transport	4.187064e-3
GO:0055086	nucleobase-containing small molecule metabolic process	4.228129e-3
GO:0071391	cellular response to estrogen stimulus	4.233682e-3
GO:0045862	positive regulation of proteolysis	4.258388e-3
GO:0010893	positive regulation of steroid biosynthetic process	4.313619e-3
GO:0014029	neural crest formation	4.327202e-3
GO:0046580	negative regulation of Ras protein signal transduction	4.332838e-3
GO:0051092	positive regulation of NF-kappaB transcription factor activity	4.393404e-3
GO:0051084	'de novo' posttranslational protein folding	4.396982e-3
GO:0002227	innate immune response in mucosa	4.422717e-3
GO:0010248	establishment or maintenance of transmembrane electrochemical gradient	4.441551e-3
GO:0006796	phosphate-containing compound metabolic process	4.470547e-3
GO:0006767	water-soluble vitamin metabolic process	4.507411e-3
GO:0043114	regulation of vascular permeability	4.559719e-3
GO:0034504	protein localization to nucleus	4.700389e-3
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	4.706640e-3
GO:0030513	positive regulation of BMP signaling pathway	4.713438e-3
GO:0061136	regulation of proteasomal protein catabolic process	4.715640e-3
GO:0042982	amyloid precursor protein metabolic process	4.771322e-3
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	4.776411e-3
GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation	4.776411e-3
GO:0006904	vesicle docking involved in exocytosis	4.825375e-3
GO:0051984	positive regulation of chromosome segregation	4.835540e-3
GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport	4.835540e-3
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	4.835540e-3
GO:0090140	regulation of mitochondrial fission	4.835540e-3
GO:0006424	glutamyl-tRNA aminoacylation	4.835540e-3
GO:0010046	response to mycotoxin	4.835540e-3
GO:0002432	granuloma formation	4.835540e-3
GO:0007004	telomere maintenance via telomerase	4.835540e-3
GO:0043547	positive regulation of GTPase activity	4.862982e-3
GO:0061316	canonical Wnt receptor signaling pathway involved in heart development	4.895018e-3
GO:0006221	pyrimidine nucleotide biosynthetic process	4.896110e-3
GO:0009912	auditory receptor cell fate commitment	4.906768e-3
GO:0045581	negative regulation of T cell differentiation	4.915980e-3
GO:0070633	transepithelial transport	4.944697e-3
GO:0009124	nucleoside monophosphate biosynthetic process	4.984352e-3
GO:0045768	positive regulation of anti-apoptosis	4.994409e-3
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	5.036450e-3
GO:0060406	positive regulation of penile erection	5.036450e-3
GO:0010288	response to lead ion	5.065588e-3
GO:0015802	basic amino acid transport	5.117573e-3
GO:0061003	positive regulation of dendritic spine morphogenesis	5.118623e-3
GO:0050665	hydrogen peroxide biosynthetic process	5.170827e-3
GO:0031272	regulation of pseudopodium assembly	5.170827e-3
GO:0006085	acetyl-CoA biosynthetic process	5.170827e-3
GO:0033622	integrin activation	5.185964e-3
GO:0071169	establishment of protein localization to chromatin	5.185964e-3
GO:0007506	gonadal mesoderm development	5.185964e-3
GO:0006409	tRNA export from nucleus	5.185964e-3
GO:0001546	preantral ovarian follicle growth	5.185964e-3
GO:0090085	regulation of protein deubiquitination	5.225248e-3
GO:0060769	positive regulation of epithelial cell proliferation involved in prostate gland development	5.225248e-3
GO:0006177	GMP biosynthetic process	5.225248e-3
GO:0018023	peptidyl-lysine trimethylation	5.286283e-3
GO:0006883	cellular sodium ion homeostasis	5.286283e-3
GO:0051298	centrosome duplication	5.289498e-3
GO:0043154	negative regulation of caspase activity	5.436970e-3
GO:0044241	lipid digestion	5.506751e-3
GO:0043217	myelin maintenance	5.550713e-3
GO:0007625	grooming behavior	5.550713e-3
GO:0060571	morphogenesis of an epithelial fold	5.576675e-3
GO:0035136	forelimb morphogenesis	5.701619e-3
GO:0019509	L-methionine salvage from methylthioadenosine	5.726005e-3
GO:0060370	susceptibility to T cell mediated cytotoxicity	5.726005e-3
GO:0009217	purine deoxyribonucleoside triphosphate catabolic process	5.726005e-3
GO:0000492	box C/D snoRNP assembly	5.726005e-3
GO:0010312	detoxification of zinc ion	5.726005e-3
GO:0048305	immunoglobulin secretion	5.746979e-3
GO:0046323	glucose import	5.755471e-3
GO:0060447	bud outgrowth involved in lung branching	5.755471e-3
GO:0010876	lipid localization	5.767680e-3
GO:0046425	regulation of JAK-STAT cascade	5.769341e-3
GO:0034623	cellular macromolecular complex disassembly	5.838345e-3
GO:0005981	regulation of glycogen catabolic process	5.884019e-3
GO:0043434	response to peptide hormone stimulus	5.886856e-3
GO:0006541	glutamine metabolic process	5.918797e-3
GO:0002446	neutrophil mediated immunity	5.967920e-3
GO:0071214	cellular response to abiotic stimulus	5.977390e-3
GO:0046824	positive regulation of nucleocytoplasmic transport	6.023017e-3
GO:0007032	endosome organization	6.076714e-3
GO:0032367	intracellular cholesterol transport	6.167811e-3
GO:0010939	regulation of necrotic cell death	6.168949e-3
GO:0006346	methylation-dependent chromatin silencing	6.177314e-3
GO:0001821	histamine secretion	6.317205e-3
GO:0006787	porphyrin-containing compound catabolic process	6.324557e-3
GO:0046131	pyrimidine ribonucleoside metabolic process	6.380471e-3
GO:0009165	nucleotide biosynthetic process	6.444239e-3
GO:0045109	intermediate filament organization	6.454327e-3
GO:0050823	peptide antigen stabilization	6.472976e-3
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	6.472976e-3
GO:0046373	L-arabinose metabolic process	6.472976e-3
GO:0018993	somatic sex determination	6.472976e-3
GO:0008616	queuosine biosynthetic process	6.472976e-3
GO:0006487	protein N-linked glycosylation	6.508703e-3
GO:0032874	positive regulation of stress-activated MAPK cascade	6.510325e-3
GO:0009150	purine ribonucleotide metabolic process	6.523433e-3
GO:0051261	protein depolymerization	6.533698e-3
GO:0032613	interleukin-10 production	6.630142e-3
GO:0052063	induction by symbiont of defense-related host nitric oxide production	6.637657e-3
GO:0050968	detection of chemical stimulus involved in sensory perception of pain	6.637657e-3
GO:0060461	right lung morphogenesis	6.637657e-3
GO:0090131	mesenchyme migration	6.637657e-3
GO:0048613	embryonic ectodermal digestive tract morphogenesis	6.637657e-3
GO:0060446	branching involved in open tracheal system development	6.637657e-3
GO:0006550	isoleucine catabolic process	6.637657e-3
GO:0048371	lateral mesodermal cell differentiation	6.637657e-3
GO:0009098	leucine biosynthetic process	6.637657e-3
GO:0014822	detection of wounding	6.637657e-3
GO:0042892	chloramphenicol transport	6.637657e-3
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	6.641152e-3
GO:0009129	pyrimidine nucleoside monophosphate metabolic process	6.676408e-3
GO:0009996	negative regulation of cell fate specification	6.702071e-3
GO:0003229	ventricular cardiac muscle tissue development	6.764015e-3
GO:0001556	oocyte maturation	6.787003e-3
GO:0009988	cell-cell recognition	6.805644e-3
GO:0010823	negative regulation of mitochondrion organization	6.822597e-3
GO:0045730	respiratory burst	6.831203e-3
GO:0009101	glycoprotein biosynthetic process	6.870343e-3
GO:0060688	regulation of morphogenesis of a branching structure	6.877356e-3
GO:0021542	dentate gyrus development	6.924349e-3
GO:0051090	regulation of sequence-specific DNA binding transcription factor activity	6.931475e-3
GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis	7.019181e-3
GO:0006518	peptide metabolic process	7.055941e-3
GO:0048278	vesicle docking	7.103726e-3
GO:0007029	endoplasmic reticulum organization	7.103726e-3
GO:0003009	skeletal muscle contraction	7.103726e-3
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	7.115839e-3
GO:0033004	negative regulation of mast cell activation	7.115839e-3
GO:0007218	neuropeptide signaling pathway	7.358818e-3
GO:0035813	regulation of renal sodium excretion	7.426202e-3
GO:0032048	cardiolipin metabolic process	7.469751e-3
GO:2000043	regulation of cardiac cell fate specification	7.469751e-3
GO:0046874	quinolinate metabolic process	7.471251e-3
GO:0046488	phosphatidylinositol metabolic process	7.660022e-3
GO:0006284	base-excision repair	7.710785e-3
GO:0050685	positive regulation of mRNA processing	7.952942e-3
GO:0031573	intra-S DNA damage checkpoint	7.999994e-3
GO:0007041	lysosomal transport	8.012369e-3
GO:0042074	cell migration involved in gastrulation	8.157666e-3