Novel motif:88

name:	motif88_CCCTCTTT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0031326	regulation of cellular biosynthetic process	4.297795e-18
GO:0009889	regulation of biosynthetic process	4.523206e-16
GO:0010829	negative regulation of glucose transport	1.086096e-15
GO:2000112	regulation of cellular macromolecule biosynthetic process	2.588318e-15
GO:0031327	negative regulation of cellular biosynthetic process	3.823163e-15
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	4.395990e-15
GO:0051252	regulation of RNA metabolic process	5.504466e-15
GO:0006355	regulation of transcription, DNA-dependent	1.191126e-14
GO:0009890	negative regulation of biosynthetic process	1.200848e-14
GO:0010558	negative regulation of macromolecule biosynthetic process	1.950783e-14
GO:0006357	regulation of transcription from RNA polymerase II promoter	4.499945e-14
GO:0010629	negative regulation of gene expression	5.229606e-14
GO:0048705	skeletal system morphogenesis	2.230831e-13
GO:0010556	regulation of macromolecule biosynthetic process	2.258155e-13
GO:0001957	intramembranous ossification	2.562907e-13
GO:0045892	negative regulation of transcription, DNA-dependent	4.655954e-13
GO:0010468	regulation of gene expression	7.601940e-13
GO:0051253	negative regulation of RNA metabolic process	1.014506e-12
GO:0051172	negative regulation of nitrogen compound metabolic process	1.535213e-12
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	2.065757e-12
GO:0002706	regulation of lymphocyte mediated immunity	2.123304e-12
GO:0019219	regulation of nucleobase-containing compound metabolic process	3.402315e-12
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	4.943038e-12
GO:0045893	positive regulation of transcription, DNA-dependent	5.627191e-12
GO:0051254	positive regulation of RNA metabolic process	5.990447e-12
GO:0051173	positive regulation of nitrogen compound metabolic process	7.008020e-12
GO:0060346	bone trabecula formation	7.806626e-12
GO:0045415	negative regulation of interleukin-8 biosynthetic process	7.889734e-12
GO:0051171	regulation of nitrogen compound metabolic process	1.047650e-11
GO:0035418	protein localization to synapse	1.114705e-11
GO:0060351	cartilage development involved in endochondral bone morphogenesis	1.125166e-11
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	1.168216e-11
GO:0009892	negative regulation of metabolic process	1.448708e-11
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	2.366141e-11
GO:0010605	negative regulation of macromolecule metabolic process	2.993670e-11
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.002921e-11
GO:0043270	positive regulation of ion transport	4.221010e-11
GO:0051239	regulation of multicellular organismal process	4.695437e-11
GO:0050890	cognition	5.770332e-11
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	6.198557e-11
GO:0010628	positive regulation of gene expression	8.531465e-11
GO:0031328	positive regulation of cellular biosynthetic process	8.764965e-11
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	9.547485e-11
GO:0002712	regulation of B cell mediated immunity	1.126347e-10
GO:0060349	bone morphogenesis	1.667700e-10
GO:0031324	negative regulation of cellular metabolic process	2.088565e-10
GO:0014070	response to organic cyclic compound	3.030931e-10
GO:0060350	endochondral bone morphogenesis	3.649707e-10
GO:0007611	learning or memory	3.821061e-10
GO:0010718	positive regulation of epithelial to mesenchymal transition	4.856459e-10
GO:0001941	postsynaptic membrane organization	4.899648e-10
GO:0002819	regulation of adaptive immune response	5.672214e-10
GO:0050877	neurological system process	6.001631e-10
GO:0002889	regulation of immunoglobulin mediated immune response	7.603911e-10
GO:0001958	endochondral ossification	8.204570e-10
GO:0002315	marginal zone B cell differentiation	8.344287e-10
GO:0045064	T-helper 2 cell differentiation	8.344287e-10
GO:0006351	transcription, DNA-dependent	1.828126e-9
GO:0014050	negative regulation of glutamate secretion	2.257911e-9
GO:0060712	spongiotrophoblast layer development	2.490770e-9
GO:0031668	cellular response to extracellular stimulus	3.615533e-9
GO:0048523	negative regulation of cellular process	3.811179e-9
GO:0002268	follicular dendritic cell differentiation	5.740217e-9
GO:0070164	negative regulation of adiponectin secretion	5.909681e-9
GO:0060355	positive regulation of cell adhesion molecule production	5.909681e-9
GO:0035505	positive regulation of myosin light chain kinase activity	5.909681e-9
GO:0002708	positive regulation of lymphocyte mediated immunity	6.179900e-9
GO:0048598	embryonic morphogenesis	6.309133e-9
GO:0010717	regulation of epithelial to mesenchymal transition	6.324160e-9
GO:0003002	regionalization	6.480348e-9
GO:0048519	negative regulation of biological process	6.488843e-9
GO:0050804	regulation of synaptic transmission	6.599159e-9
GO:0043009	chordate embryonic development	6.843806e-9
GO:0034505	tooth mineralization	6.988181e-9
GO:0071496	cellular response to external stimulus	7.018088e-9
GO:2000467	positive regulation of glycogen (starch) synthase activity	7.215087e-9
GO:0022603	regulation of anatomical structure morphogenesis	7.526019e-9
GO:0009991	response to extracellular stimulus	7.849397e-9
GO:0016140	O-glycoside metabolic process	8.548314e-9
GO:0031622	positive regulation of fever generation	8.768704e-9
GO:0031323	regulation of cellular metabolic process	1.039483e-8
GO:0010557	positive regulation of macromolecule biosynthetic process	1.210885e-8
GO:0007612	learning	1.271466e-8
GO:0070208	protein heterotrimerization	1.322802e-8
GO:0009891	positive regulation of biosynthetic process	1.476338e-8
GO:0031652	positive regulation of heat generation	1.576942e-8
GO:0070163	regulation of adiponectin secretion	1.596548e-8
GO:0060348	bone development	1.607541e-8
GO:0080090	regulation of primary metabolic process	1.615488e-8
GO:0021871	forebrain regionalization	1.748522e-8
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	1.840426e-8
GO:0034114	regulation of heterotypic cell-cell adhesion	1.840426e-8
GO:0042634	regulation of hair cycle	1.990114e-8
GO:0002439	chronic inflammatory response to antigenic stimulus	2.162727e-8
GO:0044057	regulation of system process	2.280669e-8
GO:0031325	positive regulation of cellular metabolic process	2.405480e-8
GO:0046325	negative regulation of glucose import	2.550346e-8
GO:0051797	regulation of hair follicle development	2.729818e-8
GO:0044060	regulation of endocrine process	2.950664e-8
GO:0097120	receptor localization to synapse	3.215015e-8
GO:0072578	neurotransmitter-gated ion channel clustering	3.215015e-8
GO:2000465	regulation of glycogen (starch) synthase activity	3.285888e-8
GO:0010765	positive regulation of sodium ion transport	3.363883e-8
GO:0045838	positive regulation of membrane potential	3.557007e-8
GO:0010470	regulation of gastrulation	3.956546e-8
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	4.517462e-8
GO:0009792	embryo development ending in birth or egg hatching	5.660351e-8
GO:0045840	positive regulation of mitosis	5.679944e-8
GO:0051781	positive regulation of cell division	5.764773e-8
GO:0032774	RNA biosynthetic process	6.317369e-8
GO:0051094	positive regulation of developmental process	6.581632e-8
GO:0060323	head morphogenesis	6.860003e-8
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	6.971480e-8
GO:0032355	response to estradiol stimulus	7.186834e-8
GO:0097113	alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering	7.398626e-8
GO:0060325	face morphogenesis	7.582774e-8
GO:2000463	positive regulation of excitatory postsynaptic membrane potential	8.159368e-8
GO:0007565	female pregnancy	8.770849e-8
GO:0060429	epithelium development	9.418884e-8
GO:0071637	regulation of monocyte chemotactic protein-1 production	1.086730e-7
GO:0009612	response to mechanical stimulus	1.146532e-7
GO:0010893	positive regulation of steroid biosynthetic process	1.153835e-7
GO:2000026	regulation of multicellular organismal development	1.192167e-7
GO:0007267	cell-cell signaling	1.201358e-7
GO:0060216	definitive hemopoiesis	1.273687e-7
GO:0002703	regulation of leukocyte mediated immunity	1.326891e-7
GO:0009790	embryo development	1.395404e-7
GO:0051798	positive regulation of hair follicle development	1.499058e-7
GO:0046827	positive regulation of protein export from nucleus	1.681168e-7
GO:0001503	ossification	1.726751e-7
GO:0045410	positive regulation of interleukin-6 biosynthetic process	1.793768e-7
GO:0002821	positive regulation of adaptive immune response	2.090041e-7
GO:0034116	positive regulation of heterotypic cell-cell adhesion	2.204775e-7
GO:0007613	memory	2.305952e-7
GO:0030730	sequestering of triglyceride	2.443911e-7
GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	2.481727e-7
GO:0061138	morphogenesis of a branching epithelium	2.482063e-7
GO:0046626	regulation of insulin receptor signaling pathway	2.564970e-7
GO:0048545	response to steroid hormone stimulus	3.061725e-7
GO:0060706	cell differentiation involved in embryonic placenta development	3.062389e-7
GO:0043627	response to estrogen stimulus	3.312020e-7
GO:0017145	stem cell division	3.791157e-7
GO:0046068	cGMP metabolic process	4.281735e-7
GO:0031644	regulation of neurological system process	4.361513e-7
GO:0035690	cellular response to drug	4.467926e-7
GO:0048706	embryonic skeletal system development	4.649380e-7
GO:0045765	regulation of angiogenesis	4.880604e-7
GO:0048522	positive regulation of cellular process	5.254066e-7
GO:0051302	regulation of cell division	5.421500e-7
GO:0009952	anterior/posterior pattern specification	5.454278e-7
GO:0030799	regulation of cyclic nucleotide metabolic process	5.835644e-7
GO:0010171	body morphogenesis	5.858566e-7
GO:0001660	fever generation	6.052197e-7
GO:0045766	positive regulation of angiogenesis	6.346908e-7
GO:0033129	positive regulation of histone phosphorylation	6.606078e-7
GO:0045994	positive regulation of translational initiation by iron	7.061621e-7
GO:0002037	negative regulation of L-glutamate transport	7.061621e-7
GO:0045778	positive regulation of ossification	7.297053e-7
GO:0043266	regulation of potassium ion transport	8.398682e-7
GO:0065007	biological regulation	8.518841e-7
GO:0001892	embryonic placenta development	8.567704e-7
GO:0033209	tumor necrosis factor-mediated signaling pathway	8.706767e-7
GO:0032308	positive regulation of prostaglandin secretion	9.205602e-7
GO:0050794	regulation of cellular process	9.434372e-7
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	9.621489e-7
GO:0035105	sterol regulatory element binding protein import into nucleus	9.700081e-7
GO:0002467	germinal center formation	1.085047e-6
GO:0071639	positive regulation of monocyte chemotactic protein-1 production	1.119183e-6
GO:0052697	xenobiotic glucuronidation	1.139396e-6
GO:0070980	biphenyl catabolic process	1.139396e-6
GO:0052696	flavonoid glucuronidation	1.139396e-6
GO:0016142	O-glycoside catabolic process	1.139396e-6
GO:0051552	flavone metabolic process	1.139396e-6
GO:0006789	bilirubin conjugation	1.139396e-6
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	1.182285e-6
GO:0001823	mesonephros development	1.209018e-6
GO:0002920	regulation of humoral immune response	1.211836e-6
GO:0042093	T-helper cell differentiation	1.246594e-6
GO:0071230	cellular response to amino acid stimulus	1.257867e-6
GO:0051899	membrane depolarization	1.306099e-6
GO:0051216	cartilage development	1.316895e-6
GO:0051148	negative regulation of muscle cell differentiation	1.364951e-6
GO:0010604	positive regulation of macromolecule metabolic process	1.404109e-6
GO:0033280	response to vitamin D	1.408044e-6
GO:0007389	pattern specification process	1.421201e-6
GO:0033273	response to vitamin	1.442281e-6
GO:0032753	positive regulation of interleukin-4 production	1.444255e-6
GO:0045906	negative regulation of vasoconstriction	1.460520e-6
GO:0070904	transepithelial L-ascorbic acid transport	1.487358e-6
GO:0032874	positive regulation of stress-activated MAPK cascade	1.496613e-6
GO:0010469	regulation of receptor activity	1.518036e-6
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	1.525900e-6
GO:0001890	placenta development	1.578010e-6
GO:0060670	branching involved in embryonic placenta morphogenesis	1.586518e-6
GO:0051930	regulation of sensory perception of pain	1.623838e-6
GO:0060255	regulation of macromolecule metabolic process	1.633115e-6
GO:0032892	positive regulation of organic acid transport	1.649284e-6
GO:0046543	development of secondary female sexual characteristics	1.651701e-6
GO:0050806	positive regulation of synaptic transmission	2.044107e-6
GO:0022601	menstrual cycle phase	2.048007e-6
GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	2.270252e-6
GO:0051043	regulation of membrane protein ectodomain proteolysis	2.464496e-6
GO:0050789	regulation of biological process	2.512321e-6
GO:0010467	gene expression	2.558151e-6
GO:0051901	positive regulation of mitochondrial depolarization	2.589721e-6
GO:0045787	positive regulation of cell cycle	2.658994e-6
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	3.003418e-6
GO:0014805	smooth muscle adaptation	3.081126e-6
GO:0090287	regulation of cellular response to growth factor stimulus	3.222803e-6
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	3.334008e-6
GO:0032964	collagen biosynthetic process	3.368235e-6
GO:0002437	inflammatory response to antigenic stimulus	3.465643e-6
GO:0031667	response to nutrient levels	3.519024e-6
GO:0030802	regulation of cyclic nucleotide biosynthetic process	3.622748e-6
GO:0010720	positive regulation of cell development	3.682169e-6
GO:0097119	postsynaptic density protein 95 clustering	4.099655e-6
GO:0097104	postsynaptic membrane assembly	4.099655e-6
GO:0032649	regulation of interferon-gamma production	4.197389e-6
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	4.341889e-6
GO:0031444	slow-twitch skeletal muscle fiber contraction	4.404410e-6
GO:0043588	skin development	4.457036e-6
GO:0031058	positive regulation of histone modification	4.463912e-6
GO:0051241	negative regulation of multicellular organismal process	4.469581e-6
GO:0060343	trabecula formation	4.513597e-6
GO:0051971	positive regulation of transmission of nerve impulse	4.642598e-6
GO:0097116	gephyrin clustering	4.739653e-6
GO:0048536	spleen development	4.788978e-6
GO:0046888	negative regulation of hormone secretion	4.795543e-6
GO:0072176	nephric duct development	4.883680e-6
GO:0051291	protein heterooligomerization	4.901200e-6
GO:0035272	exocrine system development	4.929512e-6
GO:0030326	embryonic limb morphogenesis	4.990587e-6
GO:0051591	response to cAMP	5.044327e-6
GO:0045684	positive regulation of epidermis development	5.196505e-6
GO:0021798	forebrain dorsal/ventral pattern formation	5.386458e-6
GO:0009893	positive regulation of metabolic process	5.802875e-6
GO:0003097	renal water transport	5.830558e-6
GO:0032729	positive regulation of interferon-gamma production	5.909701e-6
GO:0007184	SMAD protein import into nucleus	5.911777e-6
GO:0048730	epidermis morphogenesis	5.998364e-6
GO:0090303	positive regulation of wound healing	6.201360e-6
GO:0008306	associative learning	6.383842e-6
GO:0051956	negative regulation of amino acid transport	6.575778e-6
GO:0048167	regulation of synaptic plasticity	6.725161e-6
GO:0045086	positive regulation of interleukin-2 biosynthetic process	6.985430e-6
GO:0001501	skeletal system development	7.152373e-6
GO:0014819	regulation of skeletal muscle contraction	7.390573e-6
GO:0001825	blastocyst formation	7.418183e-6
GO:0035066	positive regulation of histone acetylation	7.772955e-6
GO:0031056	regulation of histone modification	8.101520e-6
GO:0042127	regulation of cell proliferation	8.385371e-6
GO:0007399	nervous system development	8.523580e-6
GO:0051130	positive regulation of cellular component organization	8.586004e-6
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	9.045829e-6
GO:0060997	dendritic spine morphogenesis	9.128894e-6
GO:0045682	regulation of epidermis development	9.521266e-6
GO:0010994	free ubiquitin chain polymerization	9.786350e-6
GO:0030213	hyaluronan biosynthetic process	9.859541e-6
GO:0070482	response to oxygen levels	9.934478e-6
GO:0048568	embryonic organ development	9.944124e-6
GO:0008544	epidermis development	1.026839e-5
GO:0032846	positive regulation of homeostatic process	1.068810e-5
GO:0045599	negative regulation of fat cell differentiation	1.077014e-5
GO:2000193	positive regulation of fatty acid transport	1.082483e-5
GO:0030814	regulation of cAMP metabolic process	1.092648e-5
GO:0010769	regulation of cell morphogenesis involved in differentiation	1.157072e-5
GO:0061383	trabecula morphogenesis	1.209357e-5
GO:0033127	regulation of histone phosphorylation	1.225554e-5
GO:0010193	response to ozone	1.255229e-5
GO:0071310	cellular response to organic substance	1.414102e-5
GO:0048771	tissue remodeling	1.473936e-5
GO:0032720	negative regulation of tumor necrosis factor production	1.547754e-5
GO:0019222	regulation of metabolic process	1.559089e-5
GO:0016242	negative regulation of macroautophagy	1.611017e-5
GO:0031111	negative regulation of microtubule polymerization or depolymerization	1.666574e-5
GO:0060708	spongiotrophoblast differentiation	1.709448e-5
GO:0031646	positive regulation of neurological system process	1.745314e-5
GO:0045662	negative regulation of myoblast differentiation	1.755232e-5
GO:0090031	positive regulation of steroid hormone biosynthetic process	1.755232e-5
GO:0042026	protein refolding	1.772753e-5
GO:0046889	positive regulation of lipid biosynthetic process	1.813604e-5
GO:0045074	regulation of interleukin-10 biosynthetic process	1.857998e-5
GO:0030817	regulation of cAMP biosynthetic process	1.894729e-5
GO:0050891	multicellular organismal water homeostasis	1.945828e-5
GO:0071417	cellular response to organic nitrogen	1.976731e-5
GO:0071300	cellular response to retinoic acid	1.984755e-5
GO:0006447	regulation of translational initiation by iron	2.028302e-5
GO:0055012	ventricular cardiac muscle cell differentiation	2.057459e-5
GO:0051454	intracellular pH elevation	2.086173e-5
GO:0071229	cellular response to acid	2.098096e-5
GO:0051928	positive regulation of calcium ion transport	2.185742e-5
GO:0060976	coronary vasculature development	2.204667e-5
GO:0003008	system process	2.233935e-5
GO:0003091	renal water homeostasis	2.340047e-5
GO:0002699	positive regulation of immune effector process	2.378168e-5
GO:0002921	negative regulation of humoral immune response	2.421738e-5
GO:0035721	intraflagellar retrograde transport	2.467387e-5
GO:0031960	response to corticosteroid stimulus	2.486854e-5
GO:0032933	SREBP-mediated signaling pathway	2.495937e-5
GO:0043279	response to alkaloid	2.546118e-5
GO:0010535	positive regulation of activation of JAK2 kinase activity	2.553098e-5
GO:0031279	regulation of cyclase activity	2.553557e-5
GO:0007435	salivary gland morphogenesis	2.569977e-5
GO:0001974	blood vessel remodeling	2.580290e-5
GO:0070309	lens fiber cell morphogenesis	2.582844e-5
GO:0043589	skin morphogenesis	2.611651e-5
GO:0071418	cellular response to amine stimulus	2.646576e-5
GO:0060486	Clara cell differentiation	2.680779e-5
GO:0045761	regulation of adenylate cyclase activity	2.703940e-5
GO:0060430	lung saccule development	2.850629e-5
GO:0060364	frontal suture morphogenesis	2.956311e-5
GO:0042696	menarche	2.963191e-5
GO:0042755	eating behavior	2.975361e-5
GO:0071495	cellular response to endogenous stimulus	3.058193e-5
GO:0021554	optic nerve development	3.175481e-5
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	3.269759e-5
GO:0032526	response to retinoic acid	3.415185e-5
GO:0016241	regulation of macroautophagy	3.437045e-5
GO:0030952	establishment or maintenance of cytoskeleton polarity	3.477307e-5
GO:0031669	cellular response to nutrient levels	3.504856e-5
GO:0010936	negative regulation of macrophage cytokine production	3.662031e-5
GO:0045136	development of secondary sexual characteristics	3.666328e-5
GO:0009653	anatomical structure morphogenesis	3.739990e-5
GO:0002293	alpha-beta T cell differentiation involved in immune response	3.890171e-5
GO:0072178	nephric duct morphogenesis	3.892595e-5
GO:0001763	morphogenesis of a branching structure	3.921866e-5
GO:0045556	positive regulation of TRAIL biosynthetic process	3.926299e-5
GO:0007610	behavior	3.943220e-5
GO:0010646	regulation of cell communication	3.961626e-5
GO:0017148	negative regulation of translation	4.032286e-5
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	4.095391e-5
GO:0045940	positive regulation of steroid metabolic process	4.253993e-5
GO:0060124	positive regulation of growth hormone secretion	4.261737e-5
GO:0002009	morphogenesis of an epithelium	4.299016e-5
GO:0051240	positive regulation of multicellular organismal process	4.376001e-5
GO:0048562	embryonic organ morphogenesis	4.376816e-5
GO:0042073	intraflagellar transport	4.507726e-5
GO:0051968	positive regulation of synaptic transmission, glutamatergic	4.607986e-5
GO:0007268	synaptic transmission	4.624044e-5
GO:0072321	chaperone-mediated protein transport	4.676290e-5
GO:0001649	osteoblast differentiation	4.702855e-5
GO:0015809	arginine transport	4.802020e-5
GO:0097118	neuroligin clustering	4.965091e-5
GO:0000302	response to reactive oxygen species	5.014988e-5
GO:0051969	regulation of transmission of nerve impulse	5.061228e-5
GO:0060035	notochord cell development	5.076249e-5
GO:0043278	response to morphine	5.164956e-5
GO:0030111	regulation of Wnt receptor signaling pathway	5.347023e-5
GO:0045657	positive regulation of monocyte differentiation	5.369146e-5
GO:0016070	RNA metabolic process	5.376345e-5
GO:0043491	protein kinase B signaling cascade	5.492337e-5
GO:0032663	regulation of interleukin-2 production	5.565715e-5
GO:0006701	progesterone biosynthetic process	5.765804e-5
GO:0042476	odontogenesis	5.837585e-5
GO:0021797	forebrain anterior/posterior pattern specification	6.007003e-5
GO:0019226	transmission of nerve impulse	6.036958e-5
GO:0042108	positive regulation of cytokine biosynthetic process	6.162180e-5
GO:0001661	conditioned taste aversion	6.174409e-5
GO:0035176	social behavior	6.242882e-5
GO:0015804	neutral amino acid transport	6.462663e-5
GO:0050886	endocrine process	6.513868e-5
GO:0072177	mesonephric duct development	6.518175e-5
GO:0048168	regulation of neuronal synaptic plasticity	6.542432e-5
GO:0019086	late viral mRNA transcription	6.544263e-5
GO:0007605	sensory perception of sound	6.851433e-5
GO:0019730	antimicrobial humoral response	6.858459e-5
GO:0003218	cardiac left ventricle formation	6.881663e-5
GO:0001829	trophectodermal cell differentiation	6.980055e-5
GO:0046628	positive regulation of insulin receptor signaling pathway	7.073839e-5
GO:0060707	trophoblast giant cell differentiation	7.240865e-5
GO:0045076	regulation of interleukin-2 biosynthetic process	7.293893e-5
GO:0045948	positive regulation of translational initiation	7.533171e-5
GO:0051339	regulation of lyase activity	7.744616e-5
GO:0060284	regulation of cell development	7.775006e-5
GO:2000273	positive regulation of receptor activity	7.902828e-5
GO:0048639	positive regulation of developmental growth	8.173261e-5
GO:0007566	embryo implantation	8.687327e-5
GO:0007431	salivary gland development	8.762281e-5
GO:0035507	regulation of myosin-light-chain-phosphatase activity	8.861956e-5
GO:0048133	male germ-line stem cell division	8.965192e-5
GO:0003417	growth plate cartilage development	8.987487e-5
GO:0071299	cellular response to vitamin A	9.230950e-5
GO:0030199	collagen fibril organization	9.392629e-5
GO:0002711	positive regulation of T cell mediated immunity	9.401510e-5
GO:0030501	positive regulation of bone mineralization	9.440261e-5
GO:0002697	regulation of immune effector process	9.686138e-5
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	9.971137e-5
GO:0002089	lens morphogenesis in camera-type eye	1.006332e-4
GO:0051896	regulation of protein kinase B signaling cascade	1.007014e-4
GO:0002544	chronic inflammatory response	1.019116e-4
GO:0001666	response to hypoxia	1.082818e-4
GO:0010715	regulation of extracellular matrix disassembly	1.174306e-4
GO:0051897	positive regulation of protein kinase B signaling cascade	1.184143e-4
GO:0070169	positive regulation of biomineral tissue development	1.227668e-4
GO:0071985	multivesicular body sorting pathway	1.273280e-4
GO:0003009	skeletal muscle contraction	1.303401e-4
GO:0072215	regulation of metanephros development	1.305306e-4
GO:0060828	regulation of canonical Wnt receptor signaling pathway	1.309882e-4
GO:0010159	specification of organ position	1.336352e-4
GO:0042593	glucose homeostasis	1.421058e-4
GO:0035752	lysosomal lumen pH elevation	1.422774e-4
GO:0000046	autophagic vacuole fusion	1.422774e-4
GO:0001575	globoside metabolic process	1.422774e-4
GO:0033591	response to L-ascorbic acid	1.477410e-4
GO:0007369	gastrulation	1.485113e-4
GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	1.486757e-4
GO:0032890	regulation of organic acid transport	1.547921e-4
GO:0035065	regulation of histone acetylation	1.549180e-4
GO:0034405	response to fluid shear stress	1.571830e-4
GO:0032872	regulation of stress-activated MAPK cascade	1.589240e-4
GO:0045637	regulation of myeloid cell differentiation	1.635610e-4
GO:0006620	posttranslational protein targeting to membrane	1.650156e-4
GO:0042946	glucoside transport	1.651830e-4
GO:0061302	smooth muscle cell-matrix adhesion	1.656942e-4
GO:0060669	embryonic placenta morphogenesis	1.662393e-4
GO:0043268	positive regulation of potassium ion transport	1.667166e-4
GO:0010225	response to UV-C	1.714895e-4
GO:0030327	prenylated protein catabolic process	1.742864e-4
GO:0009887	organ morphogenesis	1.760775e-4
GO:0045123	cellular extravasation	1.765253e-4
GO:0042035	regulation of cytokine biosynthetic process	1.843463e-4
GO:0016055	Wnt receptor signaling pathway	1.850339e-4
GO:0043932	ossification involved in bone remodeling	1.853737e-4
GO:0050881	musculoskeletal movement	1.855467e-4
GO:0016188	synaptic vesicle maturation	1.875879e-4
GO:0060444	branching involved in mammary gland duct morphogenesis	1.900877e-4
GO:2000109	regulation of macrophage apoptosis	1.904926e-4
GO:0090361	regulation of platelet-derived growth factor production	1.968478e-4
GO:0042104	positive regulation of activated T cell proliferation	2.044772e-4
GO:0002036	regulation of L-glutamate transport	2.045494e-4
GO:0001909	leukocyte mediated cytotoxicity	2.092067e-4
GO:0060322	head development	2.111672e-4
GO:0007601	visual perception	2.136844e-4
GO:0009953	dorsal/ventral pattern formation	2.182038e-4
GO:0035136	forelimb morphogenesis	2.236672e-4
GO:0010912	positive regulation of isomerase activity	2.308969e-4
GO:0010243	response to organic nitrogen	2.443700e-4
GO:0061005	cell differentiation involved in kidney development	2.504871e-4
GO:0072179	nephric duct formation	2.512925e-4
GO:0023041	neuronal signal transduction	2.513048e-4
GO:0048518	positive regulation of biological process	2.643719e-4
GO:0070633	transepithelial transport	2.684341e-4
GO:0046511	sphinganine biosynthetic process	2.733804e-4
GO:0072160	nephron tubule epithelial cell differentiation	2.744619e-4
GO:0002891	positive regulation of immunoglobulin mediated immune response	2.783323e-4
GO:0060996	dendritic spine development	2.802981e-4
GO:0010716	negative regulation of extracellular matrix disassembly	2.805011e-4
GO:0060021	palate development	2.850227e-4
GO:0008284	positive regulation of cell proliferation	2.883379e-4
GO:0050953	sensory perception of light stimulus	2.920317e-4
GO:0002028	regulation of sodium ion transport	3.095726e-4
GO:0019985	translesion synthesis	3.114329e-4
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	3.145082e-4
GO:2000110	negative regulation of macrophage apoptosis	3.186896e-4
GO:2000363	positive regulation of prostaglandin-E synthase activity	3.186896e-4
GO:0071608	macrophage inflammatory protein-1 alpha production	3.186896e-4
GO:0032701	negative regulation of interleukin-18 production	3.186896e-4
GO:0032498	detection of muramyl dipeptide	3.186896e-4
GO:0006965	positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria	3.186896e-4
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	3.227033e-4
GO:0044027	hypermethylation of CpG island	3.233968e-4
GO:0043923	positive regulation by host of viral transcription	3.236132e-4
GO:0060235	lens induction in camera-type eye	3.236132e-4
GO:0006446	regulation of translational initiation	3.255418e-4
GO:0042267	natural killer cell mediated cytotoxicity	3.261988e-4
GO:0030431	sleep	3.276962e-4
GO:0060078	regulation of postsynaptic membrane potential	3.289693e-4
GO:0061037	negative regulation of cartilage development	3.290007e-4
GO:0006621	protein retention in ER lumen	3.312628e-4
GO:0030856	regulation of epithelial cell differentiation	3.313286e-4
GO:0043586	tongue development	3.337989e-4
GO:0046069	cGMP catabolic process	3.348184e-4
GO:2000725	regulation of cardiac muscle cell differentiation	3.478053e-4
GO:0032736	positive regulation of interleukin-13 production	3.478053e-4
GO:0001817	regulation of cytokine production	3.508088e-4
GO:0007600	sensory perception	3.555066e-4
GO:0051955	regulation of amino acid transport	3.582913e-4
GO:0009804	coumarin metabolic process	3.586040e-4
GO:0060206	estrous cycle phase	3.644801e-4
GO:0001505	regulation of neurotransmitter levels	3.659414e-4
GO:0007423	sensory organ development	3.661071e-4
GO:0045911	positive regulation of DNA recombination	3.667368e-4
GO:0045061	thymic T cell selection	3.696579e-4
GO:0045414	regulation of interleukin-8 biosynthetic process	3.703850e-4
GO:0007442	hindgut morphogenesis	3.713541e-4
GO:0001704	formation of primary germ layer	3.741179e-4
GO:0048332	mesoderm morphogenesis	3.741697e-4
GO:0042256	mature ribosome assembly	3.784028e-4
GO:0035441	cell migration involved in vasculogenesis	3.784028e-4
GO:0035850	epithelial cell differentiation involved in kidney development	3.794606e-4
GO:0045408	regulation of interleukin-6 biosynthetic process	3.811016e-4
GO:0030855	epithelial cell differentiation	3.826410e-4
GO:0031343	positive regulation of cell killing	3.861504e-4
GO:0043113	receptor clustering	3.912708e-4
GO:0048704	embryonic skeletal system morphogenesis	3.924585e-4
GO:0070848	response to growth factor stimulus	3.978936e-4
GO:0006527	arginine catabolic process	4.059163e-4
GO:0021631	optic nerve morphogenesis	4.141911e-4
GO:0045191	regulation of isotype switching	4.144406e-4
GO:0008285	negative regulation of cell proliferation	4.200332e-4

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0006357	regulation of transcription from RNA polymerase II promoter	8.261708e-16
GO:0060350	endochondral bone morphogenesis	3.967179e-13
GO:0060349	bone morphogenesis	4.842435e-13
GO:0010556	regulation of macromolecule biosynthetic process	1.365472e-12
GO:0016579	protein deubiquitination	2.624979e-12
GO:0060351	cartilage development involved in endochondral bone morphogenesis	4.216312e-12
GO:2000112	regulation of cellular macromolecule biosynthetic process	4.626647e-12
GO:0003002	regionalization	4.640743e-12
GO:0010557	positive regulation of macromolecule biosynthetic process	5.346222e-12
GO:0010468	regulation of gene expression	1.592862e-11
GO:0006355	regulation of transcription, DNA-dependent	1.671059e-11
GO:0007399	nervous system development	2.508773e-11
GO:0048706	embryonic skeletal system development	3.550123e-11
GO:0045892	negative regulation of transcription, DNA-dependent	3.928620e-11
GO:0031326	regulation of cellular biosynthetic process	4.125655e-11
GO:0070646	protein modification by small protein removal	4.268086e-11
GO:0051252	regulation of RNA metabolic process	4.688007e-11
GO:0010628	positive regulation of gene expression	4.936333e-11
GO:0048731	system development	5.165366e-11
GO:0045893	positive regulation of transcription, DNA-dependent	1.214685e-10
GO:0048598	embryonic morphogenesis	1.512925e-10
GO:0001501	skeletal system development	1.536620e-10
GO:0010629	negative regulation of gene expression	1.563173e-10
GO:0048705	skeletal system morphogenesis	1.662188e-10
GO:0021871	forebrain regionalization	1.964570e-10
GO:0010604	positive regulation of macromolecule metabolic process	2.679423e-10
GO:0051254	positive regulation of RNA metabolic process	2.697703e-10
GO:0009891	positive regulation of biosynthetic process	2.935619e-10
GO:0009889	regulation of biosynthetic process	2.941586e-10
GO:0031328	positive regulation of cellular biosynthetic process	3.170521e-10
GO:0048562	embryonic organ morphogenesis	4.278790e-10
GO:0051216	cartilage development	4.844395e-10
GO:0048568	embryonic organ development	6.060841e-10
GO:0051253	negative regulation of RNA metabolic process	6.099873e-10
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	8.198033e-10
GO:0030335	positive regulation of cell migration	1.074434e-9
GO:0007275	multicellular organismal development	1.224978e-9
GO:0031327	negative regulation of cellular biosynthetic process	1.857320e-9
GO:0007389	pattern specification process	1.995999e-9
GO:0032501	multicellular organismal process	2.667056e-9
GO:0010558	negative regulation of macromolecule biosynthetic process	3.353904e-9
GO:0051272	positive regulation of cellular component movement	3.823642e-9
GO:0009890	negative regulation of biosynthetic process	4.025278e-9
GO:0060255	regulation of macromolecule metabolic process	4.567905e-9
GO:0015816	glycine transport	4.643030e-9
GO:2000147	positive regulation of cell motility	5.934384e-9
GO:0048806	genitalia development	8.364312e-9
GO:0009888	tissue development	8.480229e-9
GO:0032879	regulation of localization	8.612022e-9
GO:0009653	anatomical structure morphogenesis	1.166641e-8
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	1.234970e-8
GO:0009952	anterior/posterior pattern specification	1.256198e-8
GO:0001958	endochondral ossification	1.261359e-8
GO:0060348	bone development	1.721305e-8
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	1.843327e-8
GO:0001957	intramembranous ossification	2.053106e-8
GO:0030154	cell differentiation	2.180412e-8
GO:0010646	regulation of cell communication	2.208893e-8
GO:0006351	transcription, DNA-dependent	2.259608e-8
GO:0032502	developmental process	2.727044e-8
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	2.886443e-8
GO:0040017	positive regulation of locomotion	2.918157e-8
GO:0032774	RNA biosynthetic process	2.949743e-8
GO:0051172	negative regulation of nitrogen compound metabolic process	2.956118e-8
GO:0060346	bone trabecula formation	3.285016e-8
GO:0048864	stem cell development	3.378308e-8
GO:0048704	embryonic skeletal system morphogenesis	3.758904e-8
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	3.854177e-8
GO:0015747	urate transport	4.166600e-8
GO:0030334	regulation of cell migration	4.419873e-8
GO:0048729	tissue morphogenesis	4.553420e-8
GO:0019219	regulation of nucleobase-containing compound metabolic process	5.530420e-8
GO:0002250	adaptive immune response	5.991932e-8
GO:0071229	cellular response to acid	6.013348e-8
GO:0048699	generation of neurons	6.324751e-8
GO:0031323	regulation of cellular metabolic process	7.784339e-8
GO:0080090	regulation of primary metabolic process	7.904652e-8
GO:0022008	neurogenesis	8.193877e-8
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	8.538312e-8
GO:0009893	positive regulation of metabolic process	8.900952e-8
GO:0051173	positive regulation of nitrogen compound metabolic process	9.107592e-8
GO:0034504	protein localization to nucleus	1.036863e-7
GO:0031325	positive regulation of cellular metabolic process	1.192377e-7
GO:0045165	cell fate commitment	1.335025e-7
GO:0042989	sequestering of actin monomers	1.483831e-7
GO:0001823	mesonephros development	1.513381e-7
GO:0051270	regulation of cellular component movement	1.517927e-7
GO:0048863	stem cell differentiation	1.589999e-7
GO:0048869	cellular developmental process	1.649006e-7
GO:0051171	regulation of nitrogen compound metabolic process	1.724741e-7
GO:0048523	negative regulation of cellular process	1.746567e-7
GO:0048856	anatomical structure development	1.781034e-7
GO:0070078	histone H3-R2 demethylation	2.164489e-7
GO:0070079	histone H4-R3 demethylation	2.164489e-7
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	2.164489e-7
GO:0050793	regulation of developmental process	2.181662e-7
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	2.558693e-7
GO:0040012	regulation of locomotion	2.674909e-7
GO:0072006	nephron development	2.733440e-7
GO:0045599	negative regulation of fat cell differentiation	3.054561e-7
GO:0019827	stem cell maintenance	3.327649e-7
GO:0001503	ossification	3.615842e-7
GO:0042346	positive regulation of NF-kappaB import into nucleus	4.073516e-7
GO:0009887	organ morphogenesis	4.418404e-7
GO:0048518	positive regulation of biological process	4.650838e-7
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	4.931269e-7
GO:2000195	negative regulation of female gonad development	5.173098e-7
GO:0060675	ureteric bud morphogenesis	5.693975e-7
GO:0000904	cell morphogenesis involved in differentiation	6.190322e-7
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	6.450420e-7
GO:0021993	initiation of neural tube closure	6.463690e-7
GO:0071230	cellular response to amino acid stimulus	6.676930e-7
GO:0048519	negative regulation of biological process	6.971235e-7
GO:2000145	regulation of cell motility	7.218607e-7
GO:0009953	dorsal/ventral pattern formation	8.394776e-7
GO:0048522	positive regulation of cellular process	8.515890e-7
GO:0060325	face morphogenesis	9.821287e-7
GO:0072236	metanephric loop of Henle development	1.019516e-6
GO:0033631	cell-cell adhesion mediated by integrin	1.084985e-6
GO:0050714	positive regulation of protein secretion	1.129553e-6
GO:0001658	branching involved in ureteric bud morphogenesis	1.352807e-6
GO:0033627	cell adhesion mediated by integrin	1.374222e-6
GO:0010893	positive regulation of steroid biosynthetic process	1.507233e-6
GO:0051492	regulation of stress fiber assembly	1.522608e-6
GO:0035272	exocrine system development	1.639113e-6
GO:0060993	kidney morphogenesis	1.701064e-6
GO:0071495	cellular response to endogenous stimulus	1.707807e-6
GO:0090005	negative regulation of establishment of protein localization in plasma membrane	1.783366e-6
GO:0045785	positive regulation of cell adhesion	1.854572e-6
GO:2001076	positive regulation of metanephric ureteric bud development	1.872160e-6
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	1.872160e-6
GO:0007356	thorax and anterior abdomen determination	1.872160e-6
GO:2000026	regulation of multicellular organismal development	1.897632e-6
GO:0072070	loop of Henle development	1.970264e-6
GO:0071418	cellular response to amine stimulus	1.974950e-6
GO:0006414	translational elongation	2.024078e-6
GO:0060376	positive regulation of mast cell differentiation	2.090922e-6
GO:0006606	protein import into nucleus	2.312756e-6
GO:0030155	regulation of cell adhesion	2.445789e-6
GO:0002883	regulation of hypersensitivity	2.462966e-6
GO:0030198	extracellular matrix organization	2.513790e-6
GO:0010718	positive regulation of epithelial to mesenchymal transition	2.560009e-6
GO:0030182	neuron differentiation	2.576578e-6
GO:0061005	cell differentiation involved in kidney development	2.583459e-6
GO:0032233	positive regulation of actin filament bundle assembly	2.595193e-6
GO:0002524	hypersensitivity	2.621443e-6
GO:0008284	positive regulation of cell proliferation	2.636274e-6
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	2.900281e-6
GO:0030520	estrogen receptor signaling pathway	3.080834e-6
GO:0015851	nucleobase transport	3.246201e-6
GO:0010595	positive regulation of endothelial cell migration	3.582775e-6
GO:0072075	metanephric mesenchyme development	3.713429e-6
GO:0030539	male genitalia development	3.716701e-6
GO:0010811	positive regulation of cell-substrate adhesion	3.992912e-6
GO:0071417	cellular response to organic nitrogen	4.113833e-6
GO:2000194	regulation of female gonad development	4.198141e-6
GO:0010594	regulation of endothelial cell migration	4.220808e-6
GO:0001656	metanephros development	4.456431e-6
GO:0021515	cell differentiation in spinal cord	4.662313e-6
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	4.885677e-6
GO:0010810	regulation of cell-substrate adhesion	4.925496e-6
GO:0051049	regulation of transport	4.983493e-6
GO:0051897	positive regulation of protein kinase B signaling cascade	5.050571e-6
GO:0035019	somatic stem cell maintenance	5.063810e-6
GO:0007435	salivary gland morphogenesis	5.129480e-6
GO:0072125	negative regulation of glomerular mesangial cell proliferation	5.277785e-6
GO:0051094	positive regulation of developmental process	5.297004e-6
GO:0072107	positive regulation of ureteric bud formation	5.397628e-6
GO:0071474	cellular hyperosmotic response	5.814134e-6
GO:0090031	positive regulation of steroid hormone biosynthetic process	5.837477e-6
GO:0006863	purine base transport	6.127426e-6
GO:0051093	negative regulation of developmental process	6.309682e-6
GO:0009790	embryo development	6.314411e-6
GO:0050794	regulation of cellular process	6.542788e-6
GO:0051170	nuclear import	6.833298e-6
GO:0045596	negative regulation of cell differentiation	6.927752e-6
GO:0030111	regulation of Wnt receptor signaling pathway	7.103410e-6
GO:0001657	ureteric bud development	7.537750e-6
GO:0072074	kidney mesenchyme development	7.554610e-6
GO:0021797	forebrain anterior/posterior pattern specification	7.587255e-6
GO:0060343	trabecula formation	7.642809e-6
GO:0000902	cell morphogenesis	7.768942e-6
GO:0032231	regulation of actin filament bundle assembly	8.466114e-6
GO:0051046	regulation of secretion	8.637794e-6
GO:0007431	salivary gland development	8.982576e-6
GO:0042127	regulation of cell proliferation	9.055611e-6
GO:0010389	regulation of G2/M transition of mitotic cell cycle	9.079424e-6
GO:0048812	neuron projection morphogenesis	9.255958e-6
GO:0010717	regulation of epithelial to mesenchymal transition	1.032232e-5
GO:0051239	regulation of multicellular organismal process	1.037505e-5
GO:0050789	regulation of biological process	1.073592e-5
GO:0072166	posterior mesonephric tubule development	1.091916e-5
GO:0071295	cellular response to vitamin	1.142797e-5
GO:0060173	limb development	1.349676e-5
GO:0045628	regulation of T-helper 2 cell differentiation	1.418418e-5
GO:0035411	catenin import into nucleus	1.450461e-5
GO:0045927	positive regulation of growth	1.457783e-5
GO:0045622	regulation of T-helper cell differentiation	1.463462e-5
GO:0070208	protein heterotrimerization	1.554363e-5
GO:2000242	negative regulation of reproductive process	1.555046e-5
GO:0050867	positive regulation of cell activation	1.556102e-5
GO:0048839	inner ear development	1.593808e-5
GO:0051222	positive regulation of protein transport	1.641811e-5
GO:0002449	lymphocyte mediated immunity	1.708644e-5
GO:0032754	positive regulation of interleukin-5 production	2.036125e-5
GO:0032237	activation of store-operated calcium channel activity	2.036125e-5
GO:0050863	regulation of T cell activation	2.082077e-5
GO:0048545	response to steroid hormone stimulus	2.087191e-5
GO:0046622	positive regulation of organ growth	2.105667e-5
GO:0007420	brain development	2.182155e-5
GO:0023051	regulation of signaling	2.212205e-5
GO:0072079	nephron tubule formation	2.244142e-5
GO:0035108	limb morphogenesis	2.278453e-5
GO:0072205	metanephric collecting duct development	2.400312e-5
GO:0051050	positive regulation of transport	2.503301e-5
GO:0032094	response to food	2.593810e-5
GO:0021953	central nervous system neuron differentiation	2.615805e-5
GO:2000273	positive regulation of receptor activity	2.692853e-5
GO:0046637	regulation of alpha-beta T cell differentiation	2.852795e-5
GO:0045787	positive regulation of cell cycle	2.854130e-5
GO:0043583	ear development	2.882423e-5
GO:0031670	cellular response to nutrient	3.007096e-5
GO:0050680	negative regulation of epithelial cell proliferation	3.059971e-5
GO:0060323	head morphogenesis	3.216446e-5
GO:2000602	regulation of interphase of mitotic cell cycle	3.281410e-5
GO:0072015	glomerular visceral epithelial cell development	3.459182e-5
GO:0071260	cellular response to mechanical stimulus	3.508449e-5
GO:0046129	purine ribonucleoside biosynthetic process	3.524974e-5
GO:0002885	positive regulation of hypersensitivity	3.586013e-5
GO:0032355	response to estradiol stimulus	3.601163e-5
GO:0017196	N-terminal peptidyl-methionine acetylation	3.606275e-5
GO:0002320	lymphoid progenitor cell differentiation	3.633530e-5
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	3.713085e-5
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	3.835546e-5
GO:0048513	organ development	3.904956e-5
GO:0019222	regulation of metabolic process	3.926770e-5
GO:0043524	negative regulation of neuron apoptosis	3.961365e-5
GO:0009161	ribonucleoside monophosphate metabolic process	3.981743e-5
GO:0008037	cell recognition	4.171446e-5
GO:0090183	regulation of kidney development	4.363524e-5
GO:0060389	pathway-restricted SMAD protein phosphorylation	4.387038e-5
GO:0030326	embryonic limb morphogenesis	4.422809e-5
GO:0072278	metanephric comma-shaped body morphogenesis	4.464347e-5
GO:0072284	metanephric S-shaped body morphogenesis	4.464347e-5
GO:0060429	epithelium development	4.470446e-5
GO:0045647	negative regulation of erythrocyte differentiation	4.482415e-5
GO:0071300	cellular response to retinoic acid	4.500304e-5
GO:0030900	forebrain development	4.696943e-5
GO:0072073	kidney epithelium development	4.934504e-5
GO:0032689	negative regulation of interferon-gamma production	4.956723e-5
GO:0002443	leukocyte mediated immunity	5.061838e-5
GO:0034505	tooth mineralization	5.220563e-5
GO:0009725	response to hormone stimulus	5.309844e-5
GO:0045750	positive regulation of S phase of mitotic cell cycle	5.373599e-5
GO:0006474	N-terminal protein amino acid acetylation	5.488000e-5
GO:0042345	regulation of NF-kappaB import into nucleus	5.780515e-5
GO:0046628	positive regulation of insulin receptor signaling pathway	5.918282e-5
GO:0034329	cell junction assembly	5.962513e-5
GO:0010720	positive regulation of cell development	6.029099e-5
GO:0035295	tube development	6.105484e-5
GO:0097039	protein linear polyubiquitination	6.294673e-5
GO:0046033	AMP metabolic process	6.318109e-5
GO:0072124	regulation of glomerular mesangial cell proliferation	6.409936e-5
GO:0032736	positive regulation of interleukin-13 production	6.409936e-5
GO:0060364	frontal suture morphogenesis	6.472999e-5
GO:0016331	morphogenesis of embryonic epithelium	6.574905e-5
GO:0072112	glomerular visceral epithelial cell differentiation	7.265484e-5
GO:0072170	metanephric tubule development	7.353971e-5
GO:0009892	negative regulation of metabolic process	7.452068e-5
GO:0048667	cell morphogenesis involved in neuron differentiation	7.466885e-5
GO:0051251	positive regulation of lymphocyte activation	7.632237e-5
GO:0033025	regulation of mast cell apoptosis	7.916855e-5
GO:0031324	negative regulation of cellular metabolic process	8.097536e-5
GO:0071072	negative regulation of phospholipid biosynthetic process	8.529120e-5
GO:0032835	glomerulus development	8.636901e-5
GO:0071299	cellular response to vitamin A	8.671120e-5
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	8.683630e-5
GO:0010605	negative regulation of macromolecule metabolic process	8.801587e-5
GO:0045629	negative regulation of T-helper 2 cell differentiation	8.892749e-5
GO:0030855	epithelial cell differentiation	8.994799e-5
GO:0002696	positive regulation of leukocyte activation	9.109384e-5
GO:0090030	regulation of steroid hormone biosynthetic process	9.184466e-5
GO:0002828	regulation of type 2 immune response	9.203432e-5
GO:0009167	purine ribonucleoside monophosphate metabolic process	9.537135e-5
GO:0048663	neuron fate commitment	9.582946e-5
GO:0007409	axonogenesis	9.679251e-5
GO:0003050	regulation of systemic arterial blood pressure by atrial natriuretic peptide	9.691564e-5
GO:0007423	sensory organ development	9.811555e-5
GO:0032990	cell part morphogenesis	1.017211e-4
GO:0022612	gland morphogenesis	1.020033e-4
GO:0070231	T cell apoptosis	1.025909e-4
GO:0023035	CD40 signaling pathway	1.029882e-4
GO:0000722	telomere maintenance via recombination	1.029882e-4
GO:0001775	cell activation	1.043392e-4
GO:0045624	positive regulation of T-helper cell differentiation	1.093947e-4
GO:0072234	metanephric nephron tubule development	1.095009e-4
GO:0060231	mesenchymal to epithelial transition	1.095009e-4
GO:0002009	morphogenesis of an epithelium	1.107640e-4
GO:0030823	regulation of cGMP metabolic process	1.120587e-4
GO:0002861	regulation of inflammatory response to antigenic stimulus	1.152285e-4
GO:0060923	cardiac muscle cell fate commitment	1.154047e-4
GO:0072164	mesonephric tubule development	1.161582e-4
GO:0008361	regulation of cell size	1.170028e-4
GO:0045931	positive regulation of mitotic cell cycle	1.185500e-4
GO:2000467	positive regulation of glycogen (starch) synthase activity	1.215192e-4
GO:0048585	negative regulation of response to stimulus	1.218739e-4
GO:0032352	positive regulation of hormone metabolic process	1.241766e-4
GO:0048858	cell projection morphogenesis	1.253334e-4
GO:0042063	gliogenesis	1.253678e-4
GO:0072210	metanephric nephron development	1.293982e-4
GO:2000657	negative regulation of apolipoprotein binding	1.295569e-4
GO:0051496	positive regulation of stress fiber assembly	1.307006e-4
GO:0071214	cellular response to abiotic stimulus	1.315194e-4
GO:0021592	fourth ventricle development	1.355197e-4
GO:0034762	regulation of transmembrane transport	1.375439e-4
GO:0006366	transcription from RNA polymerase II promoter	1.437586e-4
GO:0051896	regulation of protein kinase B signaling cascade	1.492073e-4
GO:0071383	cellular response to steroid hormone stimulus	1.509860e-4
GO:0007154	cell communication	1.542014e-4
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	1.554114e-4
GO:0072001	renal system development	1.557493e-4
GO:0072080	nephron tubule development	1.587742e-4
GO:0002467	germinal center formation	1.594058e-4
GO:0051085	chaperone mediated protein folding requiring cofactor	1.595811e-4
GO:0043491	protein kinase B signaling cascade	1.618871e-4
GO:0007565	female pregnancy	1.661739e-4
GO:0043401	steroid hormone mediated signaling pathway	1.690395e-4
GO:0065007	biological regulation	1.696704e-4
GO:0001798	positive regulation of type IIa hypersensitivity	1.715729e-4
GO:0060690	epithelial cell differentiation involved in salivary gland development	1.753933e-4
GO:0002874	regulation of chronic inflammatory response to antigenic stimulus	1.753933e-4
GO:0048639	positive regulation of developmental growth	1.793179e-4
GO:0006646	phosphatidylethanolamine biosynthetic process	1.802353e-4
GO:0043410	positive regulation of MAPKKK cascade	1.879071e-4
GO:0032674	regulation of interleukin-5 production	1.931218e-4
GO:0007442	hindgut morphogenesis	1.946414e-4
GO:0061383	trabecula morphogenesis	2.042512e-4
GO:0002316	follicular B cell differentiation	2.072605e-4
GO:0010648	negative regulation of cell communication	2.161676e-4
GO:0060206	estrous cycle phase	2.177453e-4
GO:0014075	response to amine stimulus	2.227012e-4
GO:0060836	lymphatic endothelial cell differentiation	2.268516e-4
GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter	2.269143e-4
GO:0072363	regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter	2.269143e-4
GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter	2.269143e-4
GO:0048260	positive regulation of receptor-mediated endocytosis	2.301958e-4
GO:0007379	segment specification	2.304692e-4
GO:0001829	trophectodermal cell differentiation	2.366715e-4
GO:0002791	regulation of peptide secretion	2.374379e-4
GO:0072207	metanephric epithelium development	2.391204e-4
GO:0006909	phagocytosis	2.419177e-4
GO:0015711	organic anion transport	2.493745e-4
GO:0030825	positive regulation of cGMP metabolic process	2.499340e-4
GO:0010001	glial cell differentiation	2.530904e-4
GO:0051249	regulation of lymphocyte activation	2.555208e-4
GO:0023057	negative regulation of signaling	2.559265e-4
GO:0060324	face development	2.596665e-4
GO:0010543	regulation of platelet activation	2.601723e-4
GO:0060751	branch elongation involved in mammary gland duct branching	2.668053e-4
GO:0050865	regulation of cell activation	2.677738e-4
GO:0046898	response to cycloheximide	2.720056e-4
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.721760e-4
GO:0090189	regulation of branching involved in ureteric bud morphogenesis	2.733954e-4
GO:0001568	blood vessel development	2.741066e-4
GO:0001936	regulation of endothelial cell proliferation	2.756658e-4
GO:0060010	Sertoli cell fate commitment	2.776403e-4
GO:0045453	bone resorption	2.790737e-4
GO:0071071	regulation of phospholipid biosynthetic process	2.860826e-4
GO:0035148	tube formation	2.871331e-4
GO:0034616	response to laminar fluid shear stress	2.879580e-4
GO:0061326	renal tubule development	2.915788e-4
GO:0001649	osteoblast differentiation	2.934355e-4
GO:0045595	regulation of cell differentiation	2.962718e-4
GO:0060284	regulation of cell development	3.041300e-4
GO:0009967	positive regulation of signal transduction	3.080780e-4
GO:0050708	regulation of protein secretion	3.126811e-4
GO:0072179	nephric duct formation	3.127817e-4
GO:0001822	kidney development	3.171794e-4
GO:0046113	nucleobase catabolic process	3.177952e-4
GO:0001838	embryonic epithelial tube formation	3.193301e-4
GO:0007417	central nervous system development	3.220314e-4
GO:0006167	AMP biosynthetic process	3.259597e-4
GO:0006924	activation-induced cell death of T cells	3.272859e-4
GO:0046952	ketone body catabolic process	3.284189e-4
GO:0003097	renal water transport	3.314083e-4
GO:0072560	type B pancreatic cell maturation	3.340085e-4
GO:0018924	mandelate metabolic process	3.340085e-4
GO:0034405	response to fluid shear stress	3.349815e-4
GO:0046889	positive regulation of lipid biosynthetic process	3.373278e-4
GO:0072060	outer medullary collecting duct development	3.380943e-4
GO:0072061	inner medullary collecting duct development	3.380943e-4
GO:0032571	response to vitamin K	3.380943e-4
GO:0016332	establishment or maintenance of polarity of embryonic epithelium	3.380943e-4
GO:0060363	cranial suture morphogenesis	3.393253e-4
GO:0042976	activation of Janus kinase activity	3.433186e-4
GO:0042637	catagen	3.433186e-4
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	3.455786e-4
GO:0008344	adult locomotory behavior	3.491194e-4
GO:0072028	nephron morphogenesis	3.550036e-4
GO:0000060	protein import into nucleus, translocation	3.589972e-4
GO:0048702	embryonic neurocranium morphogenesis	3.596319e-4
GO:0045321	leukocyte activation	3.626965e-4
GO:0060341	regulation of cellular localization	3.654503e-4
GO:2000018	regulation of male gonad development	3.656596e-4
GO:0007422	peripheral nervous system development	3.839251e-4
GO:0007346	regulation of mitotic cell cycle	3.868860e-4
GO:0002438	acute inflammatory response to antigenic stimulus	3.914267e-4
GO:0048619	embryonic hindgut morphogenesis	3.964842e-4
GO:0048732	gland development	3.991531e-4
GO:0045081	negative regulation of interleukin-10 biosynthetic process	4.004757e-4
GO:0002115	store-operated calcium entry	4.004757e-4
GO:0042116	macrophage activation	4.037786e-4
GO:0021510	spinal cord development	4.043797e-4
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	4.066148e-4
GO:0048625	myoblast cell fate commitment	4.067621e-4
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	4.092188e-4
GO:0007166	cell surface receptor linked signaling pathway	4.196759e-4
GO:0031668	cellular response to extracellular stimulus	4.467601e-4
GO:0010544	negative regulation of platelet activation	4.529835e-4
GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway	4.580575e-4
GO:0072175	epithelial tube formation	4.645345e-4
GO:0035826	rubidium ion transport	4.654278e-4
GO:2000682	positive regulation of rubidium ion transport	4.654278e-4
GO:2000688	positive regulation of rubidium ion transmembrane transporter activity	4.654278e-4
GO:0043252	sodium-independent organic anion transport	4.654278e-4
GO:0001682	tRNA 5'-leader removal	4.654278e-4
GO:0016078	tRNA catabolic process	4.654278e-4
GO:0021528	commissural neuron differentiation in spinal cord	4.654278e-4
GO:0071496	cellular response to external stimulus	4.714683e-4
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	4.760346e-4
GO:0048701	embryonic cranial skeleton morphogenesis	4.808925e-4
GO:0043627	response to estrogen stimulus	4.885137e-4
GO:2000020	positive regulation of male gonad development	4.943537e-4
GO:0006206	pyrimidine base metabolic process	4.972515e-4
GO:0050868	negative regulation of T cell activation	4.978260e-4
GO:0021678	third ventricle development	4.986079e-4
GO:0071470	cellular response to osmotic stress	4.986079e-4
GO:0051584	regulation of dopamine uptake	4.986079e-4
GO:0040013	negative regulation of locomotion	4.986573e-4
GO:0042307	positive regulation of protein import into nucleus	4.992675e-4
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	4.998232e-4
GO:0061046	regulation of branching involved in lung morphogenesis	5.234923e-4
GO:0060421	positive regulation of heart growth	5.234923e-4
GO:0009260	ribonucleotide biosynthetic process	5.245295e-4
GO:0002040	sprouting angiogenesis	5.283080e-4
GO:0031175	neuron projection development	5.324126e-4
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	5.476191e-4
GO:0051130	positive regulation of cellular component organization	5.491974e-4
GO:0043589	skin morphogenesis	5.602606e-4
GO:0071731	response to nitric oxide	5.605214e-4
GO:0060602	branch elongation of an epithelium	5.665451e-4
GO:0043434	response to peptide hormone stimulus	5.738173e-4
GO:0051798	positive regulation of hair follicle development	5.745626e-4
GO:0002064	epithelial cell development	5.803438e-4
GO:0070668	positive regulation of mast cell proliferation	5.839657e-4
GO:0046168	glycerol-3-phosphate catabolic process	5.839657e-4
GO:0030490	maturation of SSU-rRNA	5.892731e-4
GO:0048268	clathrin coat assembly	6.050282e-4
GO:0000302	response to reactive oxygen species	6.052410e-4
GO:0016064	immunoglobulin mediated immune response	6.076975e-4
GO:0032870	cellular response to hormone stimulus	6.119694e-4
GO:0051580	regulation of neurotransmitter uptake	6.129669e-4
GO:0072240	metanephric DCT cell differentiation	6.156268e-4
GO:0072227	metanephric macula densa development	6.156268e-4
GO:0051451	myoblast migration	6.156268e-4
GO:0032096	negative regulation of response to food	6.218592e-4
GO:0001764	neuron migration	6.312556e-4
GO:0071805	potassium ion transmembrane transport	6.345542e-4
GO:0003338	metanephros morphogenesis	6.368097e-4
GO:0046649	lymphocyte activation	6.447456e-4
GO:0043010	camera-type eye development	6.471194e-4
GO:0034765	regulation of ion transmembrane transport	6.504331e-4
GO:0032526	response to retinoic acid	6.694096e-4
GO:0060482	lobar bronchus development	6.720803e-4
GO:0002052	positive regulation of neuroblast proliferation	6.734878e-4
GO:0090276	regulation of peptide hormone secretion	6.755760e-4
GO:0060014	granulosa cell differentiation	6.778288e-4
GO:0000189	MAPK import into nucleus	6.841229e-4
GO:0018206	peptidyl-methionine modification	6.841229e-4
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	6.916144e-4
GO:0014070	response to organic cyclic compound	6.958091e-4
GO:0055123	digestive system development	7.012663e-4
GO:0008286	insulin receptor signaling pathway	7.047111e-4
GO:0042993	positive regulation of transcription factor import into nucleus	7.059898e-4
GO:0071310	cellular response to organic substance	7.161254e-4
GO:0035249	synaptic transmission, glutamatergic	7.236566e-4
GO:0043299	leukocyte degranulation	7.243387e-4
GO:0051930	regulation of sensory perception of pain	7.254198e-4
GO:0023052	signaling	7.282189e-4
GO:0001654	eye development	7.344891e-4
GO:0045597	positive regulation of cell differentiation	7.506882e-4
GO:0009991	response to extracellular stimulus	7.525334e-4
GO:0019724	B cell mediated immunity	7.625622e-4
GO:0009968	negative regulation of signal transduction	7.649789e-4
GO:0035239	tube morphogenesis	7.745606e-4
GO:0006901	vesicle coating	7.823509e-4
GO:0060307	regulation of ventricular cardiomyocyte membrane repolarization	7.840157e-4
GO:0070345	negative regulation of fat cell proliferation	7.840157e-4
GO:0009637	response to blue light	7.840157e-4
GO:0060299	negative regulation of sarcomere organization	7.840157e-4