Novel motif:50

name:	motif50_GTCCNA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0051001	negative regulation of nitric-oxide synthase activity	1.543495e-9
GO:0035269	protein O-linked mannosylation	3.681316e-9
GO:0015742	alpha-ketoglutarate transport	3.011886e-8
GO:0046655	folic acid metabolic process	8.358726e-8
GO:0072109	glomerular mesangium development	1.419236e-7
GO:0006457	protein folding	1.606816e-7
GO:2000249	regulation of actin cytoskeleton reorganization	1.881829e-7
GO:0045947	negative regulation of translational initiation	4.938949e-7
GO:0050909	sensory perception of taste	5.306801e-7
GO:0043249	erythrocyte maturation	5.575751e-7
GO:0030853	negative regulation of granulocyte differentiation	7.023668e-7
GO:0000956	nuclear-transcribed mRNA catabolic process	1.219870e-6
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	1.486196e-6
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	1.865095e-6
GO:0006415	translational termination	1.925446e-6
GO:0043241	protein complex disassembly	2.683473e-6
GO:0072110	glomerular mesangial cell proliferation	3.335516e-6
GO:0007274	neuromuscular synaptic transmission	4.167013e-6
GO:0006414	translational elongation	5.092434e-6
GO:0019058	viral infectious cycle	5.569305e-6
GO:0042254	ribosome biogenesis	6.427232e-6
GO:0031365	N-terminal protein amino acid modification	6.807930e-6
GO:0032754	positive regulation of interleukin-5 production	7.444741e-6
GO:0019083	viral transcription	8.119354e-6
GO:0060712	spongiotrophoblast layer development	8.137884e-6
GO:0006402	mRNA catabolic process	8.752253e-6
GO:0006401	RNA catabolic process	9.142603e-6
GO:0043624	cellular protein complex disassembly	9.277312e-6
GO:0060457	negative regulation of digestive system process	1.059976e-5
GO:0071816	tail-anchored membrane protein insertion into ER membrane	1.129760e-5
GO:0016072	rRNA metabolic process	1.150181e-5
GO:0060713	labyrinthine layer morphogenesis	1.274240e-5
GO:0010424	DNA methylation on cytosine within a CG sequence	1.405561e-5
GO:0060711	labyrinthine layer development	1.510089e-5
GO:0006760	folic acid-containing compound metabolic process	1.804256e-5
GO:0002502	peptide antigen assembly with MHC class I protein complex	1.861318e-5
GO:0006304	DNA modification	2.750508e-5
GO:0006364	rRNA processing	2.794465e-5
GO:0071504	cellular response to heparin	2.797466e-5
GO:0046618	drug export	2.804246e-5
GO:0017148	negative regulation of translation	2.894724e-5
GO:0043045	DNA methylation involved in embryo development	3.039460e-5
GO:0051973	positive regulation of telomerase activity	3.091292e-5
GO:0030719	P granule organization	3.192900e-5
GO:0071593	lymphocyte aggregation	3.392742e-5
GO:0031848	protection from non-homologous end joining at telomere	3.528790e-5
GO:0040030	regulation of molecular function, epigenetic	3.932592e-5
GO:2000251	positive regulation of actin cytoskeleton reorganization	3.932592e-5
GO:0070489	T cell aggregation	3.972720e-5
GO:0030421	defecation	3.972720e-5
GO:0032202	telomere assembly	4.090073e-5
GO:0060708	spongiotrophoblast differentiation	4.116830e-5
GO:0002268	follicular dendritic cell differentiation	4.614832e-5
GO:0009142	nucleoside triphosphate biosynthetic process	4.696145e-5
GO:0033233	regulation of protein sumoylation	4.963080e-5
GO:0010897	negative regulation of triglyceride catabolic process	5.048116e-5
GO:0010987	negative regulation of high-density lipoprotein particle clearance	5.048116e-5
GO:0007199	G-protein signaling, coupled to cGMP nucleotide second messenger	5.358055e-5
GO:0001977	renal system process involved in regulation of blood volume	5.497784e-5
GO:0032984	macromolecular complex disassembly	5.583916e-5
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	5.850360e-5
GO:0009258	10-formyltetrahydrofolate catabolic process	6.049519e-5
GO:0003105	negative regulation of glomerular filtration	6.330099e-5
GO:0051668	localization within membrane	6.712614e-5
GO:0050779	RNA destabilization	6.729343e-5
GO:0060669	embryonic placenta morphogenesis	7.096145e-5
GO:0051205	protein insertion into membrane	7.298885e-5
GO:0070172	positive regulation of tooth mineralization	7.307570e-5
GO:0046499	S-adenosylmethioninamine metabolic process	7.598915e-5
GO:0006505	GPI anchor metabolic process	7.653605e-5
GO:0009145	purine nucleoside triphosphate biosynthetic process	8.010997e-5
GO:0060306	regulation of membrane repolarization	8.053327e-5
GO:0042558	pteridine-containing compound metabolic process	8.348579e-5
GO:0090196	regulation of chemokine secretion	9.210421e-5
GO:0071503	response to heparin	9.210421e-5
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	9.492237e-5
GO:0018023	peptidyl-lysine trimethylation	9.828032e-5
GO:0061101	neuroendocrine cell differentiation	9.877936e-5
GO:0006506	GPI anchor biosynthetic process	1.005504e-4
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	1.078533e-4
GO:0006700	C21-steroid hormone biosynthetic process	1.140907e-4
GO:0009201	ribonucleoside triphosphate biosynthetic process	1.145702e-4
GO:0030968	endoplasmic reticulum unfolded protein response	1.153262e-4
GO:0006400	tRNA modification	1.209326e-4
GO:0006695	cholesterol biosynthetic process	1.277871e-4
GO:0045842	positive regulation of mitotic metaphase/anaphase transition	1.402428e-4
GO:0016126	sterol biosynthetic process	1.432967e-4
GO:0060591	chondroblast differentiation	1.444704e-4
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	1.473462e-4
GO:0002478	antigen processing and presentation of exogenous peptide antigen	1.508793e-4
GO:0034623	cellular macromolecular complex disassembly	1.548722e-4
GO:0043089	positive regulation of Cdc42 GTPase activity	1.603513e-4
GO:0060621	negative regulation of cholesterol import	1.653234e-4
GO:0032864	activation of Cdc42 GTPase activity	1.653234e-4
GO:0046939	nucleotide phosphorylation	1.673942e-4
GO:0060620	regulation of cholesterol import	1.787736e-4
GO:0090197	positive regulation of chemokine secretion	1.831410e-4
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	1.831410e-4
GO:0072126	positive regulation of glomerular mesangial cell proliferation	1.906437e-4
GO:0071506	cellular response to mycophenolic acid	1.906437e-4
GO:0042908	xenobiotic transport	1.991714e-4
GO:0060670	branching involved in embryonic placenta morphogenesis	2.059551e-4
GO:0032736	positive regulation of interleukin-13 production	2.142473e-4
GO:0044027	hypermethylation of CpG island	2.184787e-4
GO:0022417	protein maturation by protein folding	2.222728e-4
GO:2000649	regulation of sodium ion transmembrane transporter activity	2.314458e-4
GO:0034470	ncRNA processing	2.315253e-4
GO:0019542	propionate biosynthetic process	2.354465e-4
GO:0019413	acetate biosynthetic process	2.354465e-4
GO:0018192	enzyme active site formation via L-cysteine persulfide	2.354465e-4
GO:0015761	mannose transport	2.354465e-4
GO:0070988	demethylation	2.490628e-4
GO:0034340	response to type I interferon	2.595927e-4
GO:0006335	DNA replication-dependent nucleosome assembly	2.690316e-4
GO:0032782	bile acid secretion	2.691948e-4
GO:0051208	sequestering of calcium ion	2.726669e-4
GO:0014819	regulation of skeletal muscle contraction	2.726669e-4
GO:0046533	negative regulation of photoreceptor cell differentiation	2.754812e-4
GO:0045604	regulation of epidermal cell differentiation	2.984560e-4
GO:0046498	S-adenosylhomocysteine metabolic process	3.001433e-4
GO:0030852	regulation of granulocyte differentiation	3.057423e-4
GO:0007538	primary sex determination	3.077987e-4
GO:0032203	telomere formation via telomerase	3.094015e-4
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	3.240264e-4
GO:0006826	iron ion transport	3.372793e-4
GO:0072303	positive regulation of glomerular metanephric mesangial cell proliferation	3.425862e-4
GO:0060084	synaptic transmission involved in micturition	3.483738e-4
GO:0061037	negative regulation of cartilage development	3.502470e-4
GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	3.630285e-4
GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	3.630285e-4
GO:0032938	negative regulation of translation in response to oxidative stress	3.662719e-4
GO:0031591	wybutosine biosynthetic process	3.662719e-4
GO:0010616	negative regulation of cardiac muscle adaptation	3.728131e-4
GO:0009098	leucine biosynthetic process	3.728131e-4
GO:0006550	isoleucine catabolic process	3.728131e-4
GO:0006754	ATP biosynthetic process	3.839105e-4
GO:0034442	regulation of lipoprotein oxidation	3.839985e-4
GO:0034227	tRNA thio-modification	3.839985e-4
GO:0002098	tRNA wobble uridine modification	3.839985e-4
GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response	3.975036e-4
GO:0042481	regulation of odontogenesis	4.062652e-4
GO:0046292	formaldehyde metabolic process	4.064766e-4
GO:0030573	bile acid catabolic process	4.064766e-4
GO:0035039	male pronucleus assembly	4.095546e-4
GO:0045814	negative regulation of gene expression, epigenetic	4.099138e-4
GO:0002636	positive regulation of germinal center formation	4.132375e-4
GO:0006694	steroid biosynthetic process	4.145332e-4
GO:0035854	eosinophil fate commitment	4.530202e-4
GO:0030222	eosinophil differentiation	4.530202e-4
GO:0071353	cellular response to interleukin-4	4.570064e-4
GO:0035552	oxidative single-stranded DNA demethylation	4.619234e-4
GO:0060337	type I interferon-mediated signaling pathway	4.643556e-4
GO:0060455	negative regulation of gastric acid secretion	4.891728e-4
GO:0060381	positive regulation of single-stranded telomeric DNA binding	4.891728e-4
GO:0007063	regulation of sister chromatid cohesion	4.908756e-4
GO:0046474	glycerophospholipid biosynthetic process	5.027539e-4
GO:0042218	1-aminocyclopropane-1-carboxylate biosynthetic process	5.028092e-4
GO:0032055	negative regulation of translation in response to stress	5.345354e-4
GO:0010452	histone H3-K36 methylation	5.402399e-4
GO:0030300	regulation of intestinal cholesterol absorption	5.637678e-4
GO:0051972	regulation of telomerase activity	5.657310e-4
GO:0060706	cell differentiation involved in embryonic placenta development	5.746913e-4
GO:0070670	response to interleukin-4	5.820041e-4
GO:0032312	regulation of ARF GTPase activity	5.946027e-4
GO:0015746	citrate transport	6.184724e-4
GO:0061103	carotid body glomus cell differentiation	6.294792e-4
GO:0061104	adrenal chromaffin cell differentiation	6.294792e-4
GO:0061102	stomach neuroendocrine cell differentiation	6.294792e-4
GO:0071259	cellular response to magnetism	6.294792e-4
GO:0061100	lung neuroendocrine cell differentiation	6.294792e-4
GO:0007400	neuroblast fate determination	6.294792e-4
GO:0003359	noradrenergic neuron fate commitment	6.294792e-4
GO:0060163	subpallium neuron fate commitment	6.294792e-4
GO:0060165	regulation of timing of subpallium neuron differentiation	6.294792e-4
GO:0007028	cytoplasm organization	6.307543e-4
GO:0035814	negative regulation of renal sodium excretion	7.071318e-4
GO:0060299	negative regulation of sarcomere organization	7.547701e-4
GO:0033292	T-tubule organization	7.547701e-4
GO:0048790	maintenance of presynaptic active zone structure	7.622114e-4
GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane	7.622114e-4
GO:0022613	ribonucleoprotein complex biogenesis	7.639613e-4
GO:0070170	regulation of tooth mineralization	8.348510e-4
GO:0010988	regulation of low-density lipoprotein particle clearance	8.450114e-4
GO:0015884	folic acid transport	8.465422e-4
GO:0072298	regulation of metanephric glomerulus development	8.765947e-4
GO:0032057	negative regulation of translational initiation in response to stress	8.829319e-4
GO:0045835	negative regulation of meiosis	9.176457e-4
GO:0070849	response to epidermal growth factor stimulus	9.205172e-4
GO:0045358	negative regulation of interferon-beta biosynthetic process	9.475335e-4
GO:0090084	negative regulation of inclusion body assembly	9.507454e-4
GO:0032415	regulation of sodium:hydrogen antiporter activity	9.566142e-4
GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter	9.800442e-4
GO:0042797	tRNA transcription from RNA polymerase III promoter	9.800442e-4
GO:0070483	detection of hypoxia	9.887079e-4
GO:0010989	negative regulation of low-density lipoprotein particle clearance	9.892181e-4
GO:0071843	cellular component biogenesis at cellular level	1.021315e-3
GO:0000084	S phase of mitotic cell cycle	1.055772e-3
GO:0043461	proton-transporting ATP synthase complex assembly	1.080083e-3
GO:0022415	viral reproductive process	1.082600e-3
GO:0006501	C-terminal protein lipidation	1.107726e-3
GO:0006704	glucocorticoid biosynthetic process	1.140861e-3
GO:0048873	homeostasis of number of cells within a tissue	1.167231e-3
GO:0006458	'de novo' protein folding	1.200153e-3
GO:0046778	modification by virus of host mRNA processing	1.213570e-3
GO:0030046	parallel actin filament bundle assembly	1.213570e-3
GO:0032200	telomere organization	1.232905e-3
GO:0003417	growth plate cartilage development	1.238371e-3
GO:0033153	T cell receptor V(D)J recombination	1.264009e-3
GO:0002033	vasodilation by angiotensin involved in regulation of systemic arterial blood pressure	1.291452e-3
GO:0031118	rRNA pseudouridine synthesis	1.297104e-3
GO:0023035	CD40 signaling pathway	1.297104e-3
GO:0072302	negative regulation of metanephric glomerular mesangial cell proliferation	1.435424e-3
GO:0061032	visceral serous pericardium development	1.435424e-3
GO:0006342	chromatin silencing	1.459575e-3
GO:0032674	regulation of interleukin-5 production	1.485478e-3
GO:0018410	C-terminal protein amino acid modification	1.502730e-3
GO:0051320	S phase	1.526489e-3
GO:0007296	vitellogenesis	1.540593e-3
GO:0060307	regulation of ventricular cardiomyocyte membrane repolarization	1.564062e-3
GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity	1.564062e-3
GO:0043418	homocysteine catabolic process	1.564062e-3
GO:0006535	cysteine biosynthetic process from serine	1.564062e-3
GO:0019343	cysteine biosynthetic process via cystathionine	1.564062e-3
GO:0019346	transsulfuration	1.564062e-3
GO:0048243	norepinephrine secretion	1.593860e-3
GO:0006835	dicarboxylic acid transport	1.604644e-3
GO:0003093	regulation of glomerular filtration	1.626502e-3
GO:0051323	metaphase	1.631893e-3
GO:0006942	regulation of striated muscle contraction	1.651913e-3
GO:0035645	enteric smooth muscle cell differentiation	1.718117e-3
GO:0008272	sulfate transport	1.724753e-3
GO:0006482	protein demethylation	1.727647e-3
GO:0051238	sequestering of metal ion	1.790033e-3
GO:0014741	negative regulation of muscle hypertrophy	1.813171e-3
GO:0060707	trophoblast giant cell differentiation	1.896906e-3
GO:0001892	embryonic placenta development	1.910411e-3
GO:0006621	protein retention in ER lumen	1.920157e-3
GO:0000724	double-strand break repair via homologous recombination	1.935694e-3
GO:0051084	'de novo' posttranslational protein folding	1.964065e-3
GO:0032416	negative regulation of sodium:hydrogen antiporter activity	1.973513e-3
GO:0018293	protein-FAD linkage	1.973513e-3
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	1.973513e-3
GO:0060351	cartilage development involved in endochondral bone morphogenesis	1.973581e-3
GO:0009304	tRNA transcription	2.015854e-3
GO:0072124	regulation of glomerular mesangial cell proliferation	2.028250e-3
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	2.030756e-3
GO:0010701	positive regulation of norepinephrine secretion	2.035754e-3
GO:0010172	embryonic body morphogenesis	2.119732e-3
GO:0034635	glutathione transport	2.171107e-3
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	2.171107e-3
GO:0019478	D-amino acid catabolic process	2.171107e-3
GO:0000725	recombinational repair	2.189626e-3
GO:0031296	B cell costimulation	2.303365e-3
GO:0022411	cellular component disassembly	2.322813e-3
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	2.334988e-3
GO:0097039	protein linear polyubiquitination	2.338619e-3
GO:0033599	regulation of mammary gland epithelial cell proliferation	2.377873e-3
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	2.391237e-3
GO:0000730	DNA recombinase assembly	2.547861e-3
GO:0032796	uropod organization	2.565344e-3
GO:0072262	metanephric glomerular mesangial cell proliferation involved in metanephros development	2.578813e-3
GO:0043128	positive regulation of 1-phosphatidylinositol 4-kinase activity	2.578813e-3
GO:0071670	smooth muscle cell chemotaxis	2.668162e-3
GO:0060981	cell migration involved in coronary angiogenesis	2.668162e-3
GO:0090346	cellular organofluorine metabolic process	2.668162e-3
GO:0046210	nitric oxide catabolic process	2.668162e-3
GO:0060764	cell-cell signaling involved in mammary gland development	2.668162e-3
GO:0043602	nitrate catabolic process	2.668162e-3
GO:0046294	formaldehyde catabolic process	2.668162e-3
GO:0048692	negative regulation of axon extension involved in regeneration	2.717088e-3
GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly	2.800553e-3
GO:0032780	negative regulation of ATPase activity	2.809466e-3
GO:0071347	cellular response to interleukin-1	2.820139e-3
GO:0030490	maturation of SSU-rRNA	2.851661e-3
GO:2000195	negative regulation of female gonad development	2.935970e-3
GO:0006348	chromatin silencing at telomere	2.954248e-3
GO:0072329	monocarboxylic acid catabolic process	2.962006e-3
GO:0045630	positive regulation of T-helper 2 cell differentiation	2.972008e-3
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	2.995896e-3
GO:0016926	protein desumoylation	2.995896e-3
GO:0042267	natural killer cell mediated cytotoxicity	3.016357e-3
GO:0016577	histone demethylation	3.092331e-3
GO:0006598	polyamine catabolic process	3.098429e-3
GO:0002158	osteoclast proliferation	3.098429e-3
GO:0002762	negative regulation of myeloid leukocyte differentiation	3.130739e-3
GO:0009152	purine ribonucleotide biosynthetic process	3.133189e-3
GO:0003071	renal system process involved in regulation of systemic arterial blood pressure	3.151434e-3
GO:0021548	pons development	3.186994e-3
GO:0031444	slow-twitch skeletal muscle fiber contraction	3.191864e-3
GO:0007497	posterior midgut development	3.256181e-3
GO:0060087	relaxation of vascular smooth muscle	3.258886e-3
GO:0071044	histone mRNA catabolic process	3.341759e-3
GO:0021588	cerebellum formation	3.377332e-3
GO:0022004	midbrain-hindbrain boundary maturation during brain development	3.377332e-3
GO:2000002	negative regulation of DNA damage checkpoint	3.377332e-3
GO:0021551	central nervous system morphogenesis	3.377332e-3
GO:0002082	regulation of oxidative phosphorylation	3.377332e-3
GO:0003106	negative regulation of glomerular filtration by angiotensin	3.377332e-3
GO:0006843	mitochondrial citrate transport	3.377332e-3
GO:0014895	smooth muscle hypertrophy	3.377332e-3
GO:0042274	ribosomal small subunit biogenesis	3.520625e-3
GO:0016264	gap junction assembly	3.543587e-3
GO:0030212	hyaluronan metabolic process	3.586385e-3
GO:0006266	DNA ligation	3.593689e-3
GO:2000194	regulation of female gonad development	3.631775e-3
GO:0006307	DNA dealkylation involved in DNA repair	3.719888e-3
GO:0072332	signal transduction by p53 class mediator resulting in induction of apoptosis	3.729719e-3
GO:0006306	DNA methylation	3.764740e-3
GO:0008052	sensory organ boundary specification	3.813203e-3
GO:0003416	endochondral bone growth	3.910423e-3
GO:0032020	ISG15-protein conjugation	3.965098e-3
GO:0033235	positive regulation of protein sumoylation	3.973453e-3
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	3.978308e-3
GO:0060049	regulation of protein glycosylation	4.081590e-3
GO:0071315	cellular response to morphine	4.089599e-3
GO:0071307	cellular response to vitamin K	4.089599e-3
GO:0090324	negative regulation of oxidative phosphorylation	4.089599e-3
GO:0071448	cellular response to alkyl hydroperoxide	4.089599e-3
GO:0071403	cellular response to high density lipoprotein particle stimulus	4.089599e-3
GO:0050904	diapedesis	4.089599e-3
GO:0031269	pseudopodium assembly	4.089599e-3
GO:0010255	glucose mediated signaling pathway	4.089599e-3
GO:0032900	negative regulation of neurotrophin production	4.089599e-3
GO:0032244	positive regulation of nucleoside transport	4.089599e-3
GO:0016233	telomere capping	4.157213e-3
GO:0071845	cellular component disassembly at cellular level	4.215186e-3
GO:0019062	virion attachment to host cell surface receptor	4.247068e-3
GO:0070344	regulation of fat cell proliferation	4.338849e-3
GO:0035511	oxidative DNA demethylation	4.339505e-3
GO:0045747	positive regulation of Notch signaling pathway	4.341364e-3
GO:0045616	regulation of keratinocyte differentiation	4.479012e-3
GO:0019884	antigen processing and presentation of exogenous antigen	4.485979e-3
GO:0045872	positive regulation of rhodopsin gene expression	4.507969e-3
GO:0006467	protein thiol-disulfide exchange	4.522184e-3
GO:0007386	compartment pattern specification	4.656177e-3
GO:0051775	response to redox state	4.686380e-3
GO:0043462	regulation of ATPase activity	4.703821e-3
GO:0035573	N-terminal peptidyl-serine trimethylation	4.705927e-3
GO:0035572	N-terminal peptidyl-serine dimethylation	4.705927e-3
GO:0018016	N-terminal peptidyl-proline dimethylation	4.705927e-3
GO:0018012	N-terminal peptidyl-alanine trimethylation	4.705927e-3
GO:0000089	mitotic metaphase	4.756891e-3
GO:0009119	ribonucleoside metabolic process	4.807835e-3
GO:0016139	glycoside catabolic process	4.917253e-3
GO:0021506	anterior neuropore closure	4.917253e-3
GO:0034384	high-density lipoprotein particle clearance	5.037299e-3
GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process	5.065513e-3
GO:0045006	DNA deamination	5.067875e-3
GO:0045820	negative regulation of glycolysis	5.116025e-3
GO:0006684	sphingomyelin metabolic process	5.119960e-3
GO:0006661	phosphatidylinositol biosynthetic process	5.184000e-3
GO:0031952	regulation of protein autophosphorylation	5.206330e-3
GO:0006635	fatty acid beta-oxidation	5.209225e-3
GO:0018198	peptidyl-cysteine modification	5.262404e-3
GO:0060051	negative regulation of protein glycosylation	5.326132e-3
GO:0060716	labyrinthine layer blood vessel development	5.348521e-3
GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity	5.428176e-3
GO:0032074	negative regulation of nuclease activity	5.428176e-3
GO:0031627	telomeric loop formation	5.428176e-3
GO:0015074	DNA integration	5.483872e-3
GO:0007620	copulation	5.552017e-3
GO:2000117	negative regulation of cysteine-type endopeptidase activity	5.612787e-3
GO:0048298	positive regulation of isotype switching to IgA isotypes	5.615475e-3
GO:0070328	triglyceride homeostasis	5.618922e-3
GO:0050435	beta-amyloid metabolic process	5.646733e-3
GO:0010536	positive regulation of activation of Janus kinase activity	5.679447e-3
GO:0046314	phosphocreatine biosynthetic process	5.697239e-3
GO:0048733	sebaceous gland development	5.804400e-3
GO:0014807	regulation of somitogenesis	5.804400e-3
GO:0001881	receptor recycling	5.804400e-3
GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness	5.804400e-3
GO:0046813	virion attachment, binding of host cell surface receptor	5.812649e-3
GO:0002250	adaptive immune response	5.873992e-3
GO:0018206	peptidyl-methionine modification	5.916115e-3
GO:0006651	diacylglycerol biosynthetic process	5.952925e-3
GO:0008215	spermine metabolic process	5.961623e-3
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	6.035673e-3
GO:0048632	negative regulation of skeletal muscle tissue growth	6.114394e-3
GO:0002017	regulation of blood volume by renal aldosterone	6.114394e-3
GO:0090230	regulation of centromere complex assembly	6.157825e-3
GO:0034205	beta-amyloid formation	6.157825e-3
GO:0035308	negative regulation of protein dephosphorylation	6.290322e-3
GO:0071356	cellular response to tumor necrosis factor	6.315598e-3
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	6.346029e-3
GO:0033144	negative regulation of steroid hormone receptor signaling pathway	6.375780e-3
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	6.381571e-3
GO:0001974	blood vessel remodeling	6.488999e-3
GO:0045343	regulation of MHC class I biosynthetic process	6.526130e-3
GO:0032656	regulation of interleukin-13 production	6.605997e-3
GO:0018393	internal peptidyl-lysine acetylation	6.656681e-3
GO:0051958	methotrexate transport	6.920356e-3
GO:0046022	positive regulation of transcription from RNA polymerase II promoter during mitosis	6.920356e-3
GO:0019388	galactose catabolic process	6.920356e-3
GO:0010631	epithelial cell migration	6.945966e-3
GO:0042711	maternal behavior	6.998794e-3
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	7.036140e-3
GO:0032753	positive regulation of interleukin-4 production	7.038035e-3
GO:0007184	SMAD protein import into nucleus	7.038035e-3
GO:0032776	DNA methylation on cytosine	7.153712e-3
GO:0010626	negative regulation of Schwann cell proliferation	7.153712e-3
GO:2000016	negative regulation of determination of dorsal identity	7.158898e-3
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	7.158898e-3
GO:0045796	negative regulation of intestinal cholesterol absorption	7.158898e-3
GO:0032972	regulation of muscle filament sliding speed	7.158898e-3
GO:0010949	negative regulation of intestinal phytosterol absorption	7.158898e-3
GO:0060784	regulation of cell proliferation involved in tissue homeostasis	7.162496e-3
GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis	7.162496e-3
GO:0060517	epithelial cell proliferation involved in prostatic bud elongation	7.162496e-3
GO:0035622	intrahepatic bile duct development	7.162496e-3
GO:0003415	chondrocyte hypertrophy	7.162496e-3
GO:0019100	male germ-line sex determination	7.162496e-3
GO:0002467	germinal center formation	7.271893e-3
GO:0035364	thymine transport	7.296285e-3
GO:0035344	hypoxanthine transport	7.296285e-3
GO:0031658	negative regulation of cyclin-dependent protein kinase activity involved in G1/S	7.296285e-3
GO:0007092	activation of mitotic anaphase-promoting complex activity	7.296285e-3
GO:0015854	guanine transport	7.296285e-3
GO:0033687	osteoblast proliferation	7.339658e-3
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling	7.339658e-3
GO:0000072	M phase specific microtubule process	7.358768e-3
GO:0072011	glomerular endothelium development	7.366295e-3
GO:0072144	glomerular mesangial cell development	7.366295e-3
GO:0007192	activation of adenylate cyclase activity by serotonin receptor signaling pathway	7.366295e-3
GO:0001980	regulation of systemic arterial blood pressure by ischemic conditions	7.366295e-3
GO:0010529	negative regulation of transposition	7.391657e-3
GO:0031998	regulation of fatty acid beta-oxidation	7.478561e-3
GO:0001909	leukocyte mediated cytotoxicity	7.553748e-3
GO:0006346	methylation-dependent chromatin silencing	7.582820e-3
GO:0000413	protein peptidyl-prolyl isomerization	7.585817e-3
GO:0030382	sperm mitochondrion organization	7.602176e-3
GO:0032269	negative regulation of cellular protein metabolic process	7.746889e-3
GO:0002063	chondrocyte development	7.813118e-3
GO:0090192	regulation of glomerulus development	7.844081e-3
GO:0048821	erythrocyte development	7.903137e-3
GO:0018394	peptidyl-lysine acetylation	7.918965e-3
GO:0043046	DNA methylation involved in gamete generation	7.934977e-3
GO:0051365	cellular response to potassium ion starvation	7.937910e-3
GO:0009642	response to light intensity	7.937910e-3
GO:0006097	glyoxylate cycle	7.937910e-3
GO:0045759	negative regulation of action potential	8.070217e-3
GO:0090141	positive regulation of mitochondrial fission	8.093417e-3
GO:0070345	negative regulation of fat cell proliferation	8.093417e-3
GO:0030206	chondroitin sulfate biosynthetic process	8.188882e-3
GO:0006032	chitin catabolic process	8.470275e-3
GO:0051292	nuclear pore complex assembly	8.511327e-3
GO:0010712	regulation of collagen metabolic process	8.578640e-3
GO:0072529	pyrimidine-containing compound catabolic process	8.578640e-3
GO:0030238	male sex determination	8.602432e-3
GO:0006885	regulation of pH	8.724321e-3
GO:0070474	positive regulation of uterine smooth muscle contraction	8.764675e-3
GO:0009260	ribonucleotide biosynthetic process	8.916181e-3
GO:0015893	drug transport	9.023660e-3
GO:0022009	central nervous system vasculogenesis	9.234659e-3
GO:0006475	internal protein amino acid acetylation	9.326525e-3
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	9.364008e-3
GO:0009698	phenylpropanoid metabolic process	9.418863e-3
GO:0019448	L-cysteine catabolic process	9.511699e-3
GO:0070071	proton-transporting two-sector ATPase complex assembly	9.518914e-3
GO:0032965	regulation of collagen biosynthetic process	9.525750e-3
GO:0043304	regulation of mast cell degranulation	9.606550e-3
GO:0016071	mRNA metabolic process	9.642199e-3
GO:0030277	maintenance of gastrointestinal epithelium	9.666052e-3
GO:0019061	uncoating of virus	9.685892e-3
GO:0045626	negative regulation of T-helper 1 cell differentiation	9.814759e-3
GO:0006308	DNA catabolic process	9.914489e-3
GO:0035545	determination of left/right asymmetry in nervous system	9.922299e-3
GO:0007021	tubulin complex assembly	9.981973e-3
GO:0001782	B cell homeostasis	1.001376e-2
GO:0010522	regulation of calcium ion transport into cytosol	1.003900e-2
GO:0015891	siderophore transport	1.013409e-2
GO:0061014	positive regulation of mRNA catabolic process	1.013768e-2
GO:0006544	glycine metabolic process	1.028953e-2
GO:0070734	histone H3-K27 methylation	1.042423e-2
GO:0006720	isoprenoid metabolic process	1.043042e-2
GO:0043543	protein acylation	1.044154e-2
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	1.060550e-2
GO:0030220	platelet formation	1.060999e-2
GO:0044338	canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation	1.066391e-2
GO:0044339	canonical Wnt receptor signaling pathway involved in osteoblast differentiation	1.066391e-2
GO:0072166	posterior mesonephric tubule development	1.067368e-2
GO:0033057	multicellular organismal reproductive behavior	1.071187e-2
GO:0007597	blood coagulation, intrinsic pathway	1.078643e-2
GO:0010624	regulation of Schwann cell proliferation	1.080873e-2
GO:0015874	norepinephrine transport	1.086805e-2
GO:0010982	regulation of high-density lipoprotein particle clearance	1.098937e-2
GO:0051593	response to folic acid	1.126703e-2
GO:0048205	COPI coating of Golgi vesicle	1.128428e-2
GO:0090344	negative regulation of cell aging	1.140022e-2
GO:0006228	UTP biosynthetic process	1.140127e-2
GO:0006165	nucleoside diphosphate phosphorylation	1.140127e-2
GO:0006183	GTP biosynthetic process	1.140127e-2
GO:0061383	trabecula morphogenesis	1.147239e-2
GO:0050667	homocysteine metabolic process	1.149787e-2
GO:0006596	polyamine biosynthetic process	1.152812e-2
GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity	1.153932e-2
GO:0016032	viral reproduction	1.168810e-2
GO:0008535	respiratory chain complex IV assembly	1.168923e-2
GO:0009116	nucleoside metabolic process	1.186694e-2
GO:0018924	mandelate metabolic process	1.188913e-2
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	1.189917e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0048298	positive regulation of isotype switching to IgA isotypes	5.087187e-16
GO:0090031	positive regulation of steroid hormone biosynthetic process	2.832160e-12
GO:0035094	response to nicotine	7.982866e-12
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	1.020642e-11
GO:0010893	positive regulation of steroid biosynthetic process	1.601122e-11
GO:0046886	positive regulation of hormone biosynthetic process	1.966811e-10
GO:0046628	positive regulation of insulin receptor signaling pathway	4.093426e-10
GO:0090030	regulation of steroid hormone biosynthetic process	2.772941e-9
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	2.944956e-9
GO:0002636	positive regulation of germinal center formation	5.262165e-9
GO:2000467	positive regulation of glycogen (starch) synthase activity	9.578403e-9
GO:0045980	negative regulation of nucleotide metabolic process	9.833822e-9
GO:0046889	positive regulation of lipid biosynthetic process	1.770414e-8
GO:0035691	macrophage migration inhibitory factor signaling pathway	1.863664e-8
GO:0030818	negative regulation of cAMP biosynthetic process	3.882423e-8
GO:0051897	positive regulation of protein kinase B signaling cascade	5.526059e-8
GO:0032352	positive regulation of hormone metabolic process	5.832364e-8
GO:2000465	regulation of glycogen (starch) synthase activity	7.200082e-8
GO:0048240	sperm capacitation	8.409858e-8
GO:0051085	chaperone mediated protein folding requiring cofactor	1.231205e-7
GO:0019730	antimicrobial humoral response	1.619595e-7
GO:0006693	prostaglandin metabolic process	2.154956e-7
GO:0070228	regulation of lymphocyte apoptosis	2.934126e-7
GO:0046885	regulation of hormone biosynthetic process	5.093592e-7
GO:0001516	prostaglandin biosynthetic process	5.315458e-7
GO:0010935	regulation of macrophage cytokine production	6.769577e-7
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	7.438149e-7
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	8.780937e-7
GO:0034505	tooth mineralization	1.246377e-6
GO:0019731	antibacterial humoral response	1.252636e-6
GO:0032963	collagen metabolic process	1.355870e-6
GO:0007586	digestion	1.491802e-6
GO:0051084	'de novo' posttranslational protein folding	1.522544e-6
GO:0044259	multicellular organismal macromolecule metabolic process	1.816453e-6
GO:0019724	B cell mediated immunity	1.855055e-6
GO:0060346	bone trabecula formation	2.068554e-6
GO:0002830	positive regulation of type 2 immune response	2.118199e-6
GO:0007288	sperm axoneme assembly	2.260931e-6
GO:0016064	immunoglobulin mediated immune response	2.977164e-6
GO:0044236	multicellular organismal metabolic process	3.713152e-6
GO:0090083	regulation of inclusion body assembly	3.856586e-6
GO:0070230	positive regulation of lymphocyte apoptosis	4.287194e-6
GO:0060674	placenta blood vessel development	4.484765e-6
GO:0051896	regulation of protein kinase B signaling cascade	5.882862e-6
GO:0002604	regulation of dendritic cell antigen processing and presentation	6.362905e-6
GO:0030307	positive regulation of cell growth	7.036806e-6
GO:0042104	positive regulation of activated T cell proliferation	7.538574e-6
GO:0045725	positive regulation of glycogen biosynthetic process	7.828713e-6
GO:0070232	regulation of T cell apoptosis	9.465540e-6
GO:2000273	positive regulation of receptor activity	9.836997e-6
GO:0031999	negative regulation of fatty acid beta-oxidation	1.079946e-5
GO:0045940	positive regulation of steroid metabolic process	1.616714e-5
GO:0045796	negative regulation of intestinal cholesterol absorption	1.657591e-5
GO:0010949	negative regulation of intestinal phytosterol absorption	1.657591e-5
GO:0009817	defense response to fungus, incompatible interaction	1.657591e-5
GO:0070234	positive regulation of T cell apoptosis	1.763477e-5
GO:0001957	intramembranous ossification	1.860685e-5
GO:0070243	regulation of thymocyte apoptosis	2.185849e-5
GO:0015816	glycine transport	2.275274e-5
GO:0060711	labyrinthine layer development	2.472393e-5
GO:0035082	axoneme assembly	2.616283e-5
GO:0032094	response to food	3.072929e-5
GO:0031017	exocrine pancreas development	3.102518e-5
GO:0045908	negative regulation of vasodilation	3.376311e-5
GO:0006668	sphinganine-1-phosphate metabolic process	3.466634e-5
GO:0071874	cellular response to norepinephrine stimulus	3.484939e-5
GO:0007286	spermatid development	3.912867e-5
GO:0030574	collagen catabolic process	4.344949e-5
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	4.402829e-5
GO:0046006	regulation of activated T cell proliferation	4.460900e-5
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	5.548651e-5
GO:0060631	regulation of meiosis I	5.651208e-5
GO:0010520	regulation of reciprocal meiotic recombination	5.847401e-5
GO:0014910	regulation of smooth muscle cell migration	6.618133e-5
GO:0070245	positive regulation of thymocyte apoptosis	6.923150e-5
GO:0060716	labyrinthine layer blood vessel development	7.194576e-5
GO:0002579	positive regulation of antigen processing and presentation	7.270266e-5
GO:0016140	O-glycoside metabolic process	7.346788e-5
GO:0060907	positive regulation of macrophage cytokine production	7.451195e-5
GO:0031536	positive regulation of exit from mitosis	7.484248e-5
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	8.107485e-5
GO:0090023	positive regulation of neutrophil chemotaxis	8.518011e-5
GO:0001553	luteinization	8.518011e-5
GO:0045581	negative regulation of T cell differentiation	8.704385e-5
GO:0006360	transcription from RNA polymerase I promoter	8.730454e-5
GO:0001961	positive regulation of cytokine-mediated signaling pathway	9.286319e-5
GO:0002906	negative regulation of mature B cell apoptosis	9.587299e-5
GO:0044243	multicellular organismal catabolic process	9.867483e-5
GO:2000107	negative regulation of leukocyte apoptosis	1.044622e-4
GO:0002577	regulation of antigen processing and presentation	1.099044e-4
GO:0090086	negative regulation of protein deubiquitination	1.121701e-4
GO:0010718	positive regulation of epithelial to mesenchymal transition	1.196099e-4
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	1.309989e-4
GO:0071422	succinate transmembrane transport	1.318219e-4
GO:0071300	cellular response to retinoic acid	1.329918e-4
GO:0070229	negative regulation of lymphocyte apoptosis	1.342275e-4
GO:0046069	cGMP catabolic process	1.411290e-4
GO:0046314	phosphocreatine biosynthetic process	1.494705e-4
GO:0043064	flagellum organization	1.531971e-4
GO:0051973	positive regulation of telomerase activity	1.542754e-4
GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	1.542754e-4
GO:0021893	cerebral cortex GABAergic interneuron fate commitment	1.542754e-4
GO:0060709	glycogen cell development involved in embryonic placenta development	1.604968e-4
GO:0002426	immunoglobulin production in mucosal tissue	1.605537e-4
GO:0090022	regulation of neutrophil chemotaxis	1.633486e-4
GO:2000106	regulation of leukocyte apoptosis	1.659346e-4
GO:0045834	positive regulation of lipid metabolic process	1.683468e-4
GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain	1.730751e-4
GO:0046322	negative regulation of fatty acid oxidation	1.923584e-4
GO:0051904	pigment granule transport	2.039145e-4
GO:0060323	head morphogenesis	2.085607e-4
GO:0051781	positive regulation of cell division	2.182295e-4
GO:0019285	glycine betaine biosynthetic process from choline	2.298381e-4
GO:0006383	transcription from RNA polymerase III promoter	2.298381e-4
GO:0046037	GMP metabolic process	2.345513e-4
GO:0071299	cellular response to vitamin A	2.372774e-4
GO:0050810	regulation of steroid biosynthetic process	2.501938e-4
GO:0009296	flagellum assembly	2.577540e-4
GO:0006513	protein monoubiquitination	2.644372e-4
GO:0060325	face morphogenesis	2.827508e-4
GO:0032402	melanosome transport	2.857296e-4
GO:0072428	signal transduction involved in intra-S DNA damage checkpoint	2.862118e-4
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	2.930537e-4
GO:0010025	wax biosynthetic process	2.940719e-4
GO:0006669	sphinganine-1-phosphate biosynthetic process	3.027047e-4
GO:0002513	tolerance induction to self antigen	3.039571e-4
GO:0033523	histone H2B ubiquitination	3.222858e-4
GO:0001867	complement activation, lectin pathway	3.379617e-4
GO:0048515	spermatid differentiation	3.400656e-4
GO:0051444	negative regulation of ubiquitin-protein ligase activity	3.571447e-4
GO:2001021	negative regulation of response to DNA damage stimulus	3.593184e-4
GO:0002483	antigen processing and presentation of endogenous peptide antigen	3.793385e-4
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	3.812224e-4
GO:0031848	protection from non-homologous end joining at telomere	3.812224e-4
GO:0006438	valyl-tRNA aminoacylation	3.812224e-4
GO:0031573	intra-S DNA damage checkpoint	3.815510e-4
GO:0048016	inositol phosphate-mediated signaling	3.822486e-4
GO:0043154	negative regulation of caspase activity	3.843359e-4
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	4.058764e-4
GO:0001578	microtubule bundle formation	4.085072e-4
GO:0002455	humoral immune response mediated by circulating immunoglobulin	4.158344e-4
GO:0046755	non-lytic virus budding	4.317027e-4
GO:0006354	transcription elongation, DNA-dependent	4.347226e-4
GO:0060760	positive regulation of response to cytokine stimulus	4.445904e-4
GO:2000147	positive regulation of cell motility	4.499605e-4
GO:0048936	peripheral nervous system neuron axonogenesis	4.557367e-4
GO:0006780	uroporphyrinogen III biosynthetic process	4.557367e-4
GO:0017196	N-terminal peptidyl-methionine acetylation	4.557367e-4
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	4.592395e-4
GO:0072376	protein activation cascade	4.741719e-4
GO:0007200	activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger	4.782728e-4
GO:0018158	protein oxidation	4.856016e-4
GO:0006208	pyrimidine base catabolic process	5.008337e-4
GO:0030050	vesicle transport along actin filament	5.420241e-4
GO:0045780	positive regulation of bone resorption	5.462560e-4
GO:0008286	insulin receptor signaling pathway	5.473921e-4
GO:0030335	positive regulation of cell migration	5.809391e-4
GO:0040017	positive regulation of locomotion	5.928995e-4
GO:0006412	translation	6.119665e-4
GO:0048631	regulation of skeletal muscle tissue growth	6.293354e-4
GO:0060457	negative regulation of digestive system process	6.293354e-4
GO:0042886	amide transport	6.346707e-4
GO:0032350	regulation of hormone metabolic process	6.348546e-4
GO:0010907	positive regulation of glucose metabolic process	6.455581e-4
GO:0045907	positive regulation of vasoconstriction	6.609338e-4
GO:0010225	response to UV-C	6.677649e-4
GO:0060947	cardiac vascular smooth muscle cell differentiation	6.689362e-4
GO:0090084	negative regulation of inclusion body assembly	6.830273e-4
GO:0016485	protein processing	6.856675e-4
GO:0044029	hypomethylation of CpG island	6.971113e-4
GO:0043932	ossification involved in bone remodeling	6.989482e-4
GO:0060547	negative regulation of necrotic cell death	7.426251e-4
GO:0000738	DNA catabolic process, exonucleolytic	7.426251e-4
GO:0045124	regulation of bone resorption	7.978731e-4
GO:0048486	parasympathetic nervous system development	8.188963e-4
GO:0044341	sodium-dependent phosphate transport	8.437374e-4
GO:0042663	regulation of endodermal cell fate specification	8.437374e-4
GO:0070875	positive regulation of glycogen metabolic process	8.665000e-4
GO:0007096	regulation of exit from mitosis	8.841342e-4
GO:0019229	regulation of vasoconstriction	8.981256e-4
GO:0035021	negative regulation of Rac protein signal transduction	9.106250e-4
GO:0060193	positive regulation of lipase activity	9.299956e-4
GO:0006368	transcription elongation from RNA polymerase II promoter	9.457298e-4
GO:0034393	positive regulation of smooth muscle cell apoptosis	9.841688e-4
GO:0071243	cellular response to arsenic-containing substance	9.922644e-4
GO:0008634	negative regulation of survival gene product expression	9.957534e-4
GO:0022614	membrane to membrane docking	9.957534e-4
GO:0051388	positive regulation of nerve growth factor receptor signaling pathway	9.961671e-4
GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing	9.961671e-4
GO:0010273	detoxification of copper ion	9.961671e-4
GO:0006206	pyrimidine base metabolic process	1.002421e-3
GO:0090179	planar cell polarity pathway involved in neural tube closure	1.005819e-3
GO:0014912	negative regulation of smooth muscle cell migration	1.037893e-3
GO:0015840	urea transport	1.062037e-3
GO:0051604	protein maturation	1.100277e-3
GO:0033085	negative regulation of T cell differentiation in thymus	1.109140e-3
GO:0016142	O-glycoside catabolic process	1.114979e-3
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	1.114979e-3
GO:0045620	negative regulation of lymphocyte differentiation	1.134920e-3
GO:0006378	mRNA polyadenylation	1.151650e-3
GO:0010390	histone monoubiquitination	1.153687e-3
GO:0032964	collagen biosynthetic process	1.193627e-3
GO:0060379	cardiac muscle cell myoblast differentiation	1.217087e-3
GO:0061077	chaperone-mediated protein folding	1.248820e-3
GO:0060744	mammary gland branching involved in thelarche	1.253402e-3
GO:0043279	response to alkaloid	1.280017e-3
GO:0032233	positive regulation of actin filament bundle assembly	1.283499e-3
GO:0031124	mRNA 3'-end processing	1.296123e-3
GO:0060326	cell chemotaxis	1.299924e-3
GO:0010936	negative regulation of macrophage cytokine production	1.308877e-3
GO:0006003	fructose 2,6-bisphosphate metabolic process	1.309969e-3
GO:0006734	NADH metabolic process	1.411206e-3
GO:0071894	histone H2B conserved C-terminal lysine ubiquitination	1.435509e-3
GO:0032218	riboflavin transport	1.435509e-3
GO:0007283	spermatogenesis	1.466232e-3
GO:0009303	rRNA transcription	1.505286e-3
GO:0007281	germ cell development	1.522891e-3
GO:0002903	negative regulation of B cell apoptosis	1.537894e-3
GO:0060381	positive regulation of single-stranded telomeric DNA binding	1.562675e-3
GO:0006409	tRNA export from nucleus	1.562675e-3
GO:0048632	negative regulation of skeletal muscle tissue growth	1.562675e-3
GO:0018206	peptidyl-methionine modification	1.575255e-3
GO:0043627	response to estrogen stimulus	1.606540e-3
GO:0007205	activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway	1.606820e-3
GO:0002069	columnar/cuboidal epithelial cell maturation	1.619109e-3
GO:0051905	establishment of pigment granule localization	1.681005e-3
GO:0035066	positive regulation of histone acetylation	1.938136e-3
GO:0001558	regulation of cell growth	1.938174e-3
GO:0048268	clathrin coat assembly	1.940725e-3
GO:0051272	positive regulation of cellular component movement	1.966458e-3
GO:0002485	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	1.995956e-3
GO:0021783	preganglionic parasympathetic nervous system development	1.996058e-3
GO:0010660	regulation of muscle cell apoptosis	2.015337e-3
GO:0002082	regulation of oxidative phosphorylation	2.045117e-3
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	2.072916e-3
GO:0046850	regulation of bone remodeling	2.117287e-3
GO:0032863	activation of Rac GTPase activity	2.145664e-3
GO:0006301	postreplication repair	2.153671e-3
GO:0060351	cartilage development involved in endochondral bone morphogenesis	2.160693e-3
GO:0042482	positive regulation of odontogenesis	2.202736e-3
GO:0071257	cellular response to electrical stimulus	2.227876e-3
GO:0072529	pyrimidine-containing compound catabolic process	2.234947e-3
GO:0006855	drug transmembrane transport	2.275775e-3
GO:0032869	cellular response to insulin stimulus	2.341783e-3
GO:0006901	vesicle coating	2.410515e-3
GO:0035104	positive regulation of transcription via sterol regulatory element binding	2.526187e-3
GO:0021542	dentate gyrus development	2.570950e-3
GO:0002449	lymphocyte mediated immunity	2.584034e-3
GO:0032241	positive regulation of nucleobase-containing compound transport	2.630779e-3
GO:0035886	vascular smooth muscle cell differentiation	2.657937e-3
GO:2000278	regulation of DNA biosynthetic process	2.665695e-3
GO:0006956	complement activation	2.677880e-3
GO:0060986	endocrine hormone secretion	2.684981e-3
GO:0034105	positive regulation of tissue remodeling	2.700531e-3
GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus	2.706572e-3
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	2.706572e-3
GO:0045128	negative regulation of reciprocal meiotic recombination	2.706572e-3
GO:0006311	meiotic gene conversion	2.706572e-3
GO:0034337	RNA folding	2.793026e-3
GO:0032276	regulation of gonadotropin secretion	2.812561e-3
GO:0035814	negative regulation of renal sodium excretion	2.812699e-3
GO:0034767	positive regulation of ion transmembrane transport	2.863629e-3
GO:0031638	zymogen activation	2.863629e-3
GO:0033604	negative regulation of catecholamine secretion	2.881814e-3
GO:0010763	positive regulation of fibroblast migration	2.881814e-3
GO:0032401	establishment of melanosome localization	2.903269e-3
GO:0090096	positive regulation of metanephric cap mesenchymal cell proliferation	2.960677e-3
GO:0045773	positive regulation of axon extension	3.028020e-3
GO:0006878	cellular copper ion homeostasis	3.059381e-3
GO:0031954	positive regulation of protein autophosphorylation	3.065821e-3
GO:0050868	negative regulation of T cell activation	3.090541e-3
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	3.376911e-3
GO:0002268	follicular dendritic cell differentiation	3.376911e-3
GO:0009404	toxin metabolic process	3.412777e-3
GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	3.525632e-3
GO:0032836	glomerular basement membrane development	3.525632e-3
GO:0015670	carbon dioxide transport	3.525632e-3
GO:0006265	DNA topological change	3.525632e-3
GO:0032642	regulation of chemokine production	3.569180e-3
GO:0042088	T-helper 1 type immune response	3.597678e-3
GO:0021563	glossopharyngeal nerve development	3.632583e-3
GO:0090218	positive regulation of lipid kinase activity	3.671492e-3
GO:0045927	positive regulation of growth	3.689863e-3
GO:0060324	face development	3.751254e-3
GO:0060948	cardiac vascular smooth muscle cell development	3.985833e-3
GO:0043117	positive regulation of vascular permeability	3.985833e-3
GO:0033628	regulation of cell adhesion mediated by integrin	3.990254e-3
GO:0050714	positive regulation of protein secretion	4.009314e-3
GO:0045988	negative regulation of striated muscle contraction	4.083128e-3
GO:0014805	smooth muscle adaptation	4.126823e-3
GO:0035674	tricarboxylic acid transmembrane transport	4.126823e-3
GO:0009314	response to radiation	4.151044e-3
GO:0046475	glycerophospholipid catabolic process	4.281679e-3
GO:0071217	cellular response to external biotic stimulus	4.343452e-3
GO:0072249	metanephric glomerular visceral epithelial cell development	4.343452e-3
GO:0072274	metanephric glomerular basement membrane development	4.343452e-3
GO:0048677	axon extension involved in regeneration	4.343452e-3
GO:0042700	luteinizing hormone signaling pathway	4.343452e-3
GO:0017187	peptidyl-glutamic acid carboxylation	4.343452e-3
GO:0021933	radial glia guided migration of cerebellar granule cell	4.343452e-3
GO:0002542	Factor XII activation	4.343452e-3
GO:0032700	negative regulation of interleukin-17 production	4.370615e-3
GO:0032229	negative regulation of synaptic transmission, GABAergic	4.370615e-3
GO:0046626	regulation of insulin receptor signaling pathway	4.406596e-3
GO:0002902	regulation of B cell apoptosis	4.425222e-3
GO:0061383	trabecula morphogenesis	4.427388e-3
GO:0006817	phosphate ion transport	4.449784e-3
GO:0032892	positive regulation of organic acid transport	4.449784e-3
GO:0071870	cellular response to catecholamine stimulus	4.482051e-3
GO:0043923	positive regulation by host of viral transcription	4.610597e-3
GO:0090324	negative regulation of oxidative phosphorylation	4.883491e-3
GO:0000379	tRNA-type intron splice site recognition and cleavage	4.883491e-3
GO:0015761	mannose transport	4.883491e-3
GO:0010756	positive regulation of plasminogen activation	4.883491e-3
GO:0010255	glucose mediated signaling pathway	4.883491e-3
GO:0097039	protein linear polyubiquitination	4.899328e-3
GO:0016098	monoterpenoid metabolic process	4.899328e-3
GO:0002536	respiratory burst involved in inflammatory response	4.916910e-3
GO:0048242	epinephrine secretion	4.924319e-3
GO:0051302	regulation of cell division	4.965399e-3
GO:0097084	vascular smooth muscle cell development	4.966985e-3
GO:0043248	proteasome assembly	4.966985e-3
GO:0032714	negative regulation of interleukin-5 production	4.991583e-3
GO:0051135	positive regulation of NK T cell activation	4.995461e-3
GO:0032722	positive regulation of chemokine production	4.999989e-3
GO:0006308	DNA catabolic process	5.070880e-3
GO:0060160	negative regulation of dopamine receptor signaling pathway	5.082698e-3
GO:0015746	citrate transport	5.082698e-3
GO:0007041	lysosomal transport	5.153891e-3
GO:0014895	smooth muscle hypertrophy	5.258815e-3
GO:0032065	cortical protein anchoring	5.258815e-3
GO:0003106	negative regulation of glomerular filtration by angiotensin	5.258815e-3
GO:0010976	positive regulation of neuron projection development	5.304800e-3
GO:0051148	negative regulation of muscle cell differentiation	5.372969e-3
GO:0032277	negative regulation of gonadotropin secretion	5.374312e-3
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	5.523775e-3
GO:0032274	gonadotropin secretion	5.523775e-3
GO:0001569	patterning of blood vessels	5.531074e-3
GO:0042129	regulation of T cell proliferation	5.569965e-3
GO:0021564	vagus nerve development	5.589446e-3
GO:0005979	regulation of glycogen biosynthetic process	5.639753e-3
GO:0070305	response to cGMP	5.754613e-3
GO:0016559	peroxisome fission	5.855816e-3
GO:2001020	regulation of response to DNA damage stimulus	5.865547e-3
GO:0032696	negative regulation of interleukin-13 production	6.031413e-3
GO:0060343	trabecula formation	6.101500e-3
GO:0050766	positive regulation of phagocytosis	6.158931e-3
GO:0035767	endothelial cell chemotaxis	6.171125e-3
GO:0060322	head development	6.214384e-3
GO:0071157	negative regulation of cell cycle arrest	6.290608e-3
GO:0048715	negative regulation of oligodendrocyte differentiation	6.291153e-3
GO:0006910	phagocytosis, recognition	6.315635e-3
GO:0033133	positive regulation of glucokinase activity	6.420225e-3
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	6.536626e-3
GO:0060913	cardiac cell fate determination	6.634277e-3
GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	6.642367e-3
GO:0020027	hemoglobin metabolic process	6.686394e-3
GO:0045626	negative regulation of T-helper 1 cell differentiation	6.724502e-3
GO:0010845	positive regulation of reciprocal meiotic recombination	6.724502e-3
GO:0000238	zygotene	6.724502e-3
GO:0010661	positive regulation of muscle cell apoptosis	6.916641e-3
GO:0008210	estrogen metabolic process	6.940257e-3
GO:0042744	hydrogen peroxide catabolic process	7.156645e-3
GO:0032231	regulation of actin filament bundle assembly	7.214486e-3
GO:0035813	regulation of renal sodium excretion	7.470373e-3
GO:0046880	regulation of follicle-stimulating hormone secretion	7.566781e-3
GO:0048630	skeletal muscle tissue growth	7.566781e-3
GO:0045683	negative regulation of epidermis development	7.726193e-3
GO:0070537	histone H2A K63-linked deubiquitination	7.744662e-3
GO:0042396	phosphagen biosynthetic process	7.744662e-3
GO:0033159	negative regulation of protein import into nucleus, translocation	7.744662e-3
GO:0045730	respiratory burst	7.795072e-3
GO:0032868	response to insulin stimulus	7.919303e-3
GO:0009411	response to UV	7.926137e-3
GO:0030263	apoptotic chromosome condensation	7.951170e-3
GO:0051586	positive regulation of dopamine uptake	7.951170e-3
GO:0010518	positive regulation of phospholipase activity	8.022180e-3
GO:0021993	initiation of neural tube closure	8.107402e-3
GO:0010511	regulation of phosphatidylinositol biosynthetic process	8.107402e-3
GO:0030223	neutrophil differentiation	8.142707e-3
GO:0033602	negative regulation of dopamine secretion	8.364079e-3
GO:2000191	regulation of fatty acid transport	8.451813e-3
GO:0051131	chaperone-mediated protein complex assembly	8.530299e-3
GO:0090002	establishment of protein localization in plasma membrane	8.530299e-3
GO:0010569	regulation of double-strand break repair via homologous recombination	8.547029e-3
GO:0090280	positive regulation of calcium ion import	8.620116e-3
GO:0006102	isocitrate metabolic process	8.620116e-3
GO:2000108	positive regulation of leukocyte apoptosis	8.804002e-3
GO:0033566	gamma-tubulin complex localization	8.836624e-3
GO:0031627	telomeric loop formation	8.836624e-3
GO:0061302	smooth muscle cell-matrix adhesion	8.836624e-3
GO:0021919	BMP signaling pathway involved in spinal cord dorsal/ventral patterning	8.836624e-3
GO:0016068	type I hypersensitivity	8.836624e-3
GO:0018230	peptidyl-L-cysteine S-palmitoylation	8.836624e-3
GO:0006782	protoporphyrinogen IX biosynthetic process	8.988159e-3
GO:0006273	lagging strand elongation	8.988159e-3
GO:0043951	negative regulation of cAMP-mediated signaling	9.005059e-3
GO:0015793	glycerol transport	9.005059e-3
GO:0010991	negative regulation of SMAD protein complex assembly	9.005059e-3
GO:0019058	viral infectious cycle	9.083360e-3
GO:0002385	mucosal immune response	9.171290e-3
GO:0010667	negative regulation of cardiac muscle cell apoptosis	9.200388e-3
GO:0019835	cytolysis	9.512339e-3
GO:0033599	regulation of mammary gland epithelial cell proliferation	9.679752e-3
GO:0035441	cell migration involved in vasculogenesis	9.824546e-3
GO:0002251	organ or tissue specific immune response	1.026786e-2
GO:0055070	copper ion homeostasis	1.026786e-2
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	1.034733e-2
GO:0046890	regulation of lipid biosynthetic process	1.038783e-2
GO:0071321	cellular response to cGMP	1.043854e-2
GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	1.043854e-2
GO:0001765	membrane raft assembly	1.043854e-2
GO:0033081	regulation of T cell differentiation in thymus	1.064573e-2
GO:0010717	regulation of epithelial to mesenchymal transition	1.072704e-2
GO:0048241	epinephrine transport	1.076077e-2
GO:0051590	positive regulation of neurotransmitter transport	1.076941e-2
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	1.082646e-2
GO:0046092	deoxycytidine metabolic process	1.082733e-2
GO:0003094	glomerular filtration	1.082733e-2
GO:0002575	basophil chemotaxis	1.082733e-2
GO:0002432	granuloma formation	1.082733e-2
GO:0034619	cellular chaperone-mediated protein complex assembly	1.087702e-2
GO:0051875	pigment granule localization	1.102407e-2
GO:2000484	positive regulation of interleukin-8 secretion	1.116646e-2
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	1.116798e-2
GO:0060375	regulation of mast cell differentiation	1.133625e-2
GO:0071247	cellular response to chromate	1.146583e-2
GO:0071881	inhibition of adenylate cyclase activity by adrenergic receptor signaling pathway	1.146583e-2
GO:0071882	activation of phospholipase C activity by adrenergic receptor signaling pathway	1.146583e-2
GO:0032900	negative regulation of neurotrophin production	1.146583e-2
GO:0000059	protein import into nucleus, docking	1.146583e-2
GO:0010760	negative regulation of macrophage chemotaxis	1.146583e-2
GO:0018214	protein carboxylation	1.146583e-2
GO:0032244	positive regulation of nucleoside transport	1.146583e-2
GO:0019067	viral assembly, maturation, egress, and release	1.157976e-2
GO:0008333	endosome to lysosome transport	1.196573e-2
GO:0043631	RNA polyadenylation	1.217080e-2
GO:0050760	negative regulation of thymidylate synthase biosynthetic process	1.218280e-2
GO:0043137	DNA replication, removal of RNA primer	1.218280e-2
GO:0007174	epidermal growth factor catabolic process	1.218280e-2
GO:0015732	prostaglandin transport	1.218280e-2
GO:0010740	positive regulation of intracellular protein kinase cascade	1.229793e-2
GO:0006099	tricarboxylic acid cycle	1.237961e-2
GO:0032846	positive regulation of homeostatic process	1.240033e-2
GO:0060159	regulation of dopamine receptor signaling pathway	1.240406e-2
GO:0051006	positive regulation of lipoprotein lipase activity	1.241047e-2
GO:0045647	negative regulation of erythrocyte differentiation	1.241047e-2
GO:0006626	protein targeting to mitochondrion	1.252549e-2
GO:0051954	positive regulation of amine transport	1.258515e-2
GO:0048013	ephrin receptor signaling pathway	1.271267e-2
GO:0032606	type I interferon production	1.281051e-2
GO:0033137	negative regulation of peptidyl-serine phosphorylation	1.306819e-2
GO:0043467	regulation of generation of precursor metabolites and energy	1.309033e-2
GO:0050863	regulation of T cell activation	1.309920e-2
GO:0022616	DNA strand elongation	1.332672e-2
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	1.342709e-2
GO:0009062	fatty acid catabolic process	1.358055e-2
GO:0050432	catecholamine secretion	1.360374e-2
GO:0043921	modulation by host of viral transcription	1.374241e-2
GO:0009914	hormone transport	1.396391e-2
GO:0032228	regulation of synaptic transmission, GABAergic	1.396776e-2
GO:0034103	regulation of tissue remodeling	1.400718e-2
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.409307e-2
GO:0050917	sensory perception of umami taste	1.409307e-2
GO:0032784	regulation of transcription elongation, DNA-dependent	1.422005e-2
GO:0048545	response to steroid hormone stimulus	1.422726e-2
GO:0045835	negative regulation of meiosis	1.428245e-2
GO:0045358	negative regulation of interferon-beta biosynthetic process	1.449916e-2
GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway	1.449916e-2
GO:0021586	pons maturation	1.449916e-2
GO:0002478	antigen processing and presentation of exogenous peptide antigen	1.452439e-2
GO:0090150	establishment of protein localization in membrane	1.457482e-2
GO:0042321	negative regulation of circadian sleep/wake cycle, sleep	1.460907e-2
GO:0046544	development of secondary male sexual characteristics	1.460907e-2
GO:0044342	type B pancreatic cell proliferation	1.479412e-2
GO:0042996	regulation of Golgi to plasma membrane protein transport	1.479412e-2
GO:0008298	intracellular mRNA localization	1.479412e-2
GO:0030321	transepithelial chloride transport	1.481595e-2
GO:0006991	response to sterol depletion	1.481595e-2
GO:0051492	regulation of stress fiber assembly	1.488638e-2
GO:0014707	branchiomeric skeletal muscle development	1.492103e-2
GO:0046125	pyrimidine deoxyribonucleoside metabolic process	1.492103e-2
GO:0032849	positive regulation of cellular pH reduction	1.499115e-2
GO:0045332	phospholipid translocation	1.506801e-2
GO:0010700	negative regulation of norepinephrine secretion	1.506801e-2
GO:0040009	regulation of growth rate	1.506801e-2
GO:0050909	sensory perception of taste	1.507102e-2
GO:0051096	positive regulation of helicase activity	1.508248e-2
GO:0001835	blastocyst hatching	1.508248e-2
GO:0045116	protein neddylation	1.508248e-2
GO:0043088	regulation of Cdc42 GTPase activity	1.520094e-2
GO:0019218	regulation of steroid metabolic process	1.523976e-2
GO:0035025	positive regulation of Rho protein signal transduction	1.575669e-2
GO:0050768	negative regulation of neurogenesis	1.597822e-2
GO:0006635	fatty acid beta-oxidation	1.602289e-2
GO:0014819	regulation of skeletal muscle contraction	1.603533e-2
GO:0032855	positive regulation of Rac GTPase activity	1.607901e-2
GO:0034616	response to laminar fluid shear stress	1.616052e-2
GO:0006670	sphingosine metabolic process	1.617063e-2
GO:0046113	nucleobase catabolic process	1.621820e-2