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MCL coexpression mm9:994: Difference between revisions

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{{MCL_coexpression_mm9
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system development;0.0219142058839643;21386!GO:0007569;cell aging;0.0219142058839643;21386!GO:0035136;forelimb morphogenesis;0.0219142058839643;21386!GO:0030879;mammary gland development;0.0241056264723607;21386!GO:0007568;aging;0.02454391059004;21386!GO:0003007;heart morphogenesis;0.0248361000018262;21386!GO:0048754;branching morphogenesis of a tube;0.0266341886897412;21386!GO:0001763;morphogenesis of a branching structure;0.0266341886897412;21386!GO:0048732;gland development;0.0266341886897412;21386!GO:0035107;appendage morphogenesis;0.0266341886897412;21386!GO:0035108;limb morphogenesis;0.0266341886897412;21386!GO:0048736;appendage development;0.0266341886897412;21386!GO:0060173;limb development;0.0266341886897412;21386!GO:0030900;forebrain development;0.0313060084056633;21386!GO:0001701;in utero embryonic development;0.0347705400025567;21386!GO:0035239;tube morphogenesis;0.0372541500027393;21386!GO:0016564;transcription repressor activity;0.0372541500027393;21386!GO:0007507;heart development;0.0372541500027393;21386!GO:0007420;brain development;0.0372541500027393;21386!GO:0045892;negative regulation of transcription, DNA-dependent;0.0372541500027393;21386!GO:0035295;tube development;0.0372541500027393;21386!GO:0001568;blood vessel development;0.0372541500027393;21386!GO:0001944;vasculature development;0.0372541500027393;21386!GO:0043009;chordate embryonic development;0.0372541500027393;21386!GO:0009792;embryonic development ending in birth or egg hatching;0.0372541500027393;21386!GO:0007417;central nervous system development;0.0372541500027393;21386!GO:0045893;positive regulation of transcription, DNA-dependent;0.0372541500027393;21386!GO:0016481;negative regulation of transcription;0.0372541500027393;21386!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0385387758649027;21386!GO:0045941;positive regulation of transcription;0.0399934257382348;21386!GO:0045935;positive regulation of nucleobase, 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|gostat_on_MCL_coexpression=GO:0021761;limbic system development;0.0219142058839643;21386!GO:0007569;cell aging;0.0219142058839643;21386!GO:0035136;forelimb morphogenesis;0.0219142058839643;21386!GO:0030879;mammary gland development;0.0241056264723607;21386!GO:0007568;aging;0.02454391059004;21386!GO:0003007;heart morphogenesis;0.0248361000018262;21386!GO:0048754;branching morphogenesis of a tube;0.0266341886897412;21386!GO:0001763;morphogenesis of a branching structure;0.0266341886897412;21386!GO:0048732;gland development;0.0266341886897412;21386!GO:0035107;appendage morphogenesis;0.0266341886897412;21386!GO:0035108;limb morphogenesis;0.0266341886897412;21386!GO:0048736;appendage development;0.0266341886897412;21386!GO:0060173;limb development;0.0266341886897412;21386!GO:0030900;forebrain development;0.0313060084056633;21386!GO:0001701;in utero embryonic development;0.0347705400025567;21386!GO:0035239;tube morphogenesis;0.0372541500027393;21386!GO:0016564;transcription repressor activity;0.0372541500027393;21386!GO:0007507;heart development;0.0372541500027393;21386!GO:0007420;brain development;0.0372541500027393;21386!GO:0045892;negative regulation of transcription, DNA-dependent;0.0372541500027393;21386!GO:0035295;tube development;0.0372541500027393;21386!GO:0001568;blood vessel development;0.0372541500027393;21386!GO:0001944;vasculature development;0.0372541500027393;21386!GO:0043009;chordate embryonic development;0.0372541500027393;21386!GO:0009792;embryonic development ending in birth or egg hatching;0.0372541500027393;21386!GO:0007417;central nervous system development;0.0372541500027393;21386!GO:0045893;positive regulation of transcription, DNA-dependent;0.0372541500027393;21386!GO:0016481;negative regulation of transcription;0.0372541500027393;21386!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0385387758649027;21386!GO:0045941;positive regulation of transcription;0.0399934257382348;21386!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0399934257382348;21386!GO:0031324;negative regulation of cellular metabolic process;0.0399934257382348;21386!GO:0009892;negative regulation of metabolic process;0.0438284117679286;21386!GO:0031325;positive regulation of cellular metabolic process;0.0449885756088443;21386!GO:0009893;positive regulation of metabolic process;0.0460824443731363;21386!
|ontology_enrichment_celltype=CL:0000107!2.09e-07!9
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0005157!7.70e-10!20;UBERON:0000468!3.25e-09!333;UBERON:0002048!4.67e-09!14;UBERON:0000117!4.67e-09!14;UBERON:0000171!4.67e-09!14;UBERON:0000170!4.67e-09!14;UBERON:0005597!4.67e-09!14;UBERON:0000118!4.67e-09!14;UBERON:0003064!4.13e-08!14;UBERON:0005153!6.79e-08!17;UBERON:0000922!1.41e-07!320;UBERON:0002410!2.09e-07!9;UBERON:0006554!3.33e-07!18;UBERON:0001008!6.47e-07!19
}}

Latest revision as of 16:13, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr5:120020745..120020748,-p@chr5:120020745..120020748
-
Mm9::chr5:120121262..120121282,+p6@Tbx3
Mm9::chr5:120121369..120121378,-p3@ENSMUST00000129108
Mm9::chr5:120121387..120121407,-p1@ENSMUST00000129108
Mm9::chr5:120121507..120121519,-p2@ENSMUST00000129108
Mm9::chr5:120121599..120121622,+p@chr5:120121599..120121622
+
Mm9::chr5:120121661..120121671,+p@chr5:120121661..120121671
+
Mm9::chr5:120121692..120121708,+p@chr5:120121692..120121708
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0021761limbic system development0.0219142058839643
GO:0007569cell aging0.0219142058839643
GO:0035136forelimb morphogenesis0.0219142058839643
GO:0030879mammary gland development0.0241056264723607
GO:0007568aging0.02454391059004
GO:0003007heart morphogenesis0.0248361000018262
GO:0048754branching morphogenesis of a tube0.0266341886897412
GO:0001763morphogenesis of a branching structure0.0266341886897412
GO:0048732gland development0.0266341886897412
GO:0035107appendage morphogenesis0.0266341886897412
GO:0035108limb morphogenesis0.0266341886897412
GO:0048736appendage development0.0266341886897412
GO:0060173limb development0.0266341886897412
GO:0030900forebrain development0.0313060084056633
GO:0001701in utero embryonic development0.0347705400025567
GO:0035239tube morphogenesis0.0372541500027393
GO:0016564transcription repressor activity0.0372541500027393
GO:0007507heart development0.0372541500027393
GO:0007420brain development0.0372541500027393
GO:0045892negative regulation of transcription, DNA-dependent0.0372541500027393
GO:0035295tube development0.0372541500027393
GO:0001568blood vessel development0.0372541500027393
GO:0001944vasculature development0.0372541500027393
GO:0043009chordate embryonic development0.0372541500027393
GO:0009792embryonic development ending in birth or egg hatching0.0372541500027393
GO:0007417central nervous system development0.0372541500027393
GO:0045893positive regulation of transcription, DNA-dependent0.0372541500027393
GO:0016481negative regulation of transcription0.0372541500027393
GO:0045934negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0385387758649027
GO:0045941positive regulation of transcription0.0399934257382348
GO:0045935positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0399934257382348
GO:0031324negative regulation of cellular metabolic process0.0399934257382348
GO:0009892negative regulation of metabolic process0.0438284117679286
GO:0031325positive regulation of cellular metabolic process0.0449885756088443
GO:0009893positive regulation of metabolic process0.0460824443731363



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
autonomic neuron2.09e-079

Uber Anatomy
Ontology termp-valuen
epithelial fold7.70e-1020
multi-cellular organism3.25e-09333
lung4.67e-0914
respiratory tube4.67e-0914
respiration organ4.67e-0914
pair of lungs4.67e-0914
lung primordium4.67e-0914
lung bud4.67e-0914
intermediate mesoderm4.13e-0814
epithelial bud6.79e-0817
embryo1.41e-07320
autonomic nervous system2.09e-079
urinary system structure3.33e-0718
renal system6.47e-0719


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.241599
MA0004.10.434673
MA0006.10.271714
MA0007.10.419994
MA0009.10.870101
MA0014.10.012738
MA0017.10.296816
MA0019.10.688051
MA0024.10.826339
MA0025.11.10341
MA0027.12.51754
MA0028.10.281528
MA0029.10.804619
MA0030.10.811181
MA0031.10.775627
MA0038.10.577528
MA0040.10.882616
MA0041.10.360875
MA0042.10.348174
MA0043.10.966833
MA0046.10.906029
MA0048.10.102483
MA0050.10.472794
MA0051.10.586414
MA0052.10.890676
MA0055.10.0283571
MA0056.10
MA0057.11.07246
MA0058.10.341628
MA0059.10.353484
MA0060.10.197678
MA0061.10.638933
MA0063.10
MA0066.10.566617
MA0067.11.21448
MA0068.10.0965831
MA0069.10.891016
MA0070.10.881319
MA0071.10.471969
MA0072.10.872842
MA0073.11.1212e-05
MA0074.10.531046
MA0076.10.315013
MA0077.10.851175
MA0078.10.61926
MA0081.10.375851
MA0083.10.96604
MA0084.11.54225
MA0087.10.922929
MA0088.12.36189
MA0089.10
MA0090.10.401197
MA0091.10.447561
MA0092.10.401504
MA0093.10.289361
MA0095.10
MA0098.10
MA0100.10.519598
MA0101.10.362124
MA0103.10.307078
MA0105.10.823589
MA0106.10.626997
MA0107.10.301222
MA0108.20.710846
MA0109.10
MA0111.10.415012
MA0113.10.598933
MA0114.10.222763
MA0115.10.969632
MA0116.10.27152
MA0117.10.937363
MA0119.10.362692
MA0122.10.957212
MA0124.11.16127
MA0125.11.0872
MA0130.10
MA0131.10.683521
MA0132.10
MA0133.10
MA0135.11.00325
MA0136.10.550755
MA0139.10.169849
MA0140.10.519484
MA0141.10.325895
MA0142.10.761136
MA0143.10.615203
MA0144.10.640537
MA0145.10.900473
MA0146.10.0169049
MA0147.10.236889
MA0148.10.450593
MA0149.10.367458
MA0062.20.137653
MA0035.20.524137
MA0039.20.254826
MA0138.20.675599
MA0002.22.2393
MA0137.20.32312
MA0104.20.18504
MA0047.20.576767
MA0112.20.0701537
MA0065.20.0704227
MA0150.10.419883
MA0151.10
MA0152.11.41249
MA0153.11.01988
MA0154.10.100744
MA0155.12.00864
MA0156.10.314185
MA0157.10.729116
MA0158.10
MA0159.10.246253
MA0160.10.453546
MA0161.10
MA0162.10.230918
MA0163.10.0186439
MA0164.10.551114
MA0080.20.302064
MA0018.20.560731
MA0099.20.669311
MA0079.21.19114
MA0102.21.59466
MA0258.10.210437
MA0259.10.227035
MA0442.10