MCL coexpression mm9:1025: Difference between revisions
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{{MCL_coexpression_mm9 | 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of epithelial cell polarity;0.0176214447361656;15227!GO:0030859;polarized epithelial cell differentiation;0.0176214447361656;15227!GO:0035089;establishment of apical/basal cell polarity;0.0176214447361656;15227!GO:0045197;establishment and/or maintenance of epithelial cell polarity;0.0176214447361656;15227!GO:0035088;establishment and/or maintenance of apical/basal cell polarity;0.0176214447361656;15227!GO:0001738;morphogenesis of a polarized epithelium;0.0176214447361656;15227!GO:0030010;establishment of cell polarity;0.0176214447361656;15227!GO:0048566;embryonic gut development;0.0176214447361656;15227!GO:0048565;gut development;0.0216849603820765;15227!GO:0007163;establishment and/or maintenance of cell polarity;0.0260176733532009;15227!GO:0001570;vasculogenesis;0.0285761028610465;15227!GO:0030855;epithelial cell differentiation;0.0308432971942609;15227!GO:0048568;embryonic organ development;0.0308432971942609;15227!GO:0007179;transforming growth factor beta receptor signaling pathway;0.0325006961650463;12160!GO:0048513;organ development;0.0325006961650463;15227,12160!GO:0051216;cartilage development;0.0325006961650463;12160!GO:0030198;extracellular matrix organization and biogenesis;0.0363153402358759;15227!GO:0030324;lung development;0.0370449151759794;15227!GO:0030323;respiratory tube development;0.0370449151759794;15227!GO:0048731;system development;0.0371793008965218;15227,12160!GO:0048869;cellular developmental process;0.0371793008965218;15227,12160!GO:0030154;cell differentiation;0.0371793008965218;15227,12160!GO:0007178;transmembrane receptor protein serine/threonine kinase signaling pathway;0.0371793008965218;12160!GO:0001503;ossification;0.0397919222532879;12160!GO:0031214;biomineral formation;0.0397919222532879;12160!GO:0043062;extracellular structure organization and biogenesis;0.0397919222532879;15227!GO:0048856;anatomical structure development;0.0397919222532879;15227,12160!GO:0046849;bone remodeling;0.0397919222532879;12160!GO:0048771;tissue remodeling;0.043510276184561;12160!GO:0002009;morphogenesis of an epithelium;0.043510276184561;15227!GO:0007275;multicellular organismal 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|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,0,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,0.373039446463946,0,0,0,-0.0611293222874226,0,0,-0.00154748369056074,0,0,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,0,-0.0611293222874226,-0.00846253853340387,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,0,0,0,0,0,-0.0611293222874226,-0.0611293222874226,0,0,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,0,0,0,0,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,-0.0233340696584343,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,0,-0.0195720377718515,0,0,0.0516706472848098,0.0479937644036057,0.0600126189759312,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,0,0,-0.0611293222874226,-0.0159973480263422,0,0,0,-0.0611293222874226,0.000623985402756634,0.112145192034931,0.0933296615241452,0,-0.0294275787049755,0,0.221362450951087,0.396867606562509,0,0,0.200866766488319,0.0996473036687316,0.236217688278263,-0.0611293222874226,0,-0.0611293222874226,0,0,0,-0.0611293222874226,0,0,0,0.245926317651782,0,0,0.0717287025946314,0.115432590314795,0.0675843291993101,0,0.0306000195230731,0,0.512052865058765,0.0374397385171714,0,0,0,0,0.856492705492007,0,0,0.296288115903851,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,0,0,-0.0611293222874226,-0.0311999484694313,0,0,0,0.0980317817133869,0,0,0,0,-0.0611293222874226,0,0.00122422220381524,-0.0611293222874226,-0.0581013801628183,0,0,0,0,0,0,0,0,0,0,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,0,0.0915002620172692,0,0.168347036942697,0,0.0479517783046174,0,0.0420835621102283,0,0,0,0,0,0,0,0,0.0425379529581421,0,0.313403641258937,0.843361802026556,0.832886635468424,0.675517721466291,0.775581306066608,0.821952057490189,0.625616364378449,0.583653179863698,0.641919912778859,0.59168342587615,0.868509876371349,0.783616232866627,0.505142099544583,0.618890154235365,0.660789219714841,0.0348473425698773,0.169042041180933,0,0.120191580279107,0.142359732304287,0.107394261255838,0,0,0,0.0346654955459424,0.437414674086382,0.144092762839815,0.140108153822136,0.253444755960825,0.206442762994762,0.293298154786566,0.334857183265246,0.435554021529114,0.453551102870363,0.321856331993588,0.427535889262335,0.638416222351445,0.616838864724281,0.577304215051994,0.23491941546046,0.388692634028637,1.04035616217637,0.713390657229626,1.00543958202828,0.919027789179529,1.12070199336583,1.21066810060338,1.05107788608828,1.12199116373229,1.2852348824557,1.31870761741455,1.21954303368998,1.22197016476223,1.12065122512038,1.23845539176103,-0.0611293222874226,-0.0611293222874226,0,-0.0549474808905443,0.0598067581751967,0,0,0,-0.0416830600141183,0,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,-0.0525240647425379,-0.0611293222874226,-0.0611293222874226,-0.0161128359202233,0,0.0576433181427177,0.132301710080237,0.172795775280084,0.138037326797407,0,0.233179609083634,0.280344013671734,0.133611193224808,0.214390645928567,0.287125017839874,0.425644821012536,0.134665885471472,0.0712896364779774,0.390395118069972,0,-0.0611293222874226,-0.0611293222874226,0.133577925442038,0,0.023209918109119,0,0.0713665499857744,0.00502845218818564,0,0.0915514965999916,0.356215685647852,0,0,0,0,-0.0121547495677054,0,0.695377280363183,0,-0.0295007185396757,0.246780347704247,0.191893350882575,0,0,0,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,0.587038450077457,0.665320140199487,0.773413674892608,0.820613726731806,0.861692620574189,0.756959983405197,0.796554179606259,0.826274949804432,0.72042618347013,0.685582376436925,0,0,0,0,0,0.0527554171614426,0.0172986928028943,0.0481920468563092,0.0393820939646292,0,0,0,0,0.0491638249932542,0.0744933641321686,0,0,0,-0.0611293222874226,-0.0611293222874226,0,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,-0.0611293222874226,0,0,0,0,0.879424833959412,0.0860494934903872,0.0294023061657368,0.0548887275343478,0,0,-0.0611293222874226,0,0,-0.0611293222874226,0,0,0,-0.0194460089283749,0,0.210244682285048,0.145825435924841,0.179609468438842,0.295000909831166,0.191185617619174,0.392828464370476,0.379983514940949,0.387789300396402,0.358634647190438,0.390232370477072,0.358878095737742,0.380919050829796,0.401774258754985,0.491907883051857,0.430740281251374,0.32427692852616,0.406944550830704,0.435718511354535,0.515738108514392,0.303651209980129,0.246068759555923,0.446741765955426,0.525424744965774,0.491306606280184,0.477633282089454,0.495975530572231,0.456648447017477,0.453545823251582,0.412915665138367,0.326803611095607,0.396727014808193,0.411091683365513,0.421097641412443,0.421339262374887,0.437141410095906,0.175981558593572,0.380860325368858,0.584651816004308,0,0,0 | |||
|gostat_on_MCL_coexpression=GO:0045198;establishment of epithelial cell polarity;0.0176214447361656;15227!GO:0030859;polarized epithelial cell differentiation;0.0176214447361656;15227!GO:0035089;establishment of apical/basal cell polarity;0.0176214447361656;15227!GO:0045197;establishment and/or maintenance of epithelial cell polarity;0.0176214447361656;15227!GO:0035088;establishment and/or maintenance of apical/basal cell polarity;0.0176214447361656;15227!GO:0001738;morphogenesis of a polarized epithelium;0.0176214447361656;15227!GO:0030010;establishment of cell polarity;0.0176214447361656;15227!GO:0048566;embryonic gut development;0.0176214447361656;15227!GO:0048565;gut development;0.0216849603820765;15227!GO:0007163;establishment and/or maintenance of cell polarity;0.0260176733532009;15227!GO:0001570;vasculogenesis;0.0285761028610465;15227!GO:0030855;epithelial cell differentiation;0.0308432971942609;15227!GO:0048568;embryonic organ development;0.0308432971942609;15227!GO:0007179;transforming growth factor beta receptor signaling pathway;0.0325006961650463;12160!GO:0048513;organ development;0.0325006961650463;15227,12160!GO:0051216;cartilage development;0.0325006961650463;12160!GO:0030198;extracellular matrix organization and biogenesis;0.0363153402358759;15227!GO:0030324;lung development;0.0370449151759794;15227!GO:0030323;respiratory tube development;0.0370449151759794;15227!GO:0048731;system development;0.0371793008965218;15227,12160!GO:0048869;cellular developmental process;0.0371793008965218;15227,12160!GO:0030154;cell differentiation;0.0371793008965218;15227,12160!GO:0007178;transmembrane receptor protein serine/threonine kinase signaling pathway;0.0371793008965218;12160!GO:0001503;ossification;0.0397919222532879;12160!GO:0031214;biomineral formation;0.0397919222532879;12160!GO:0043062;extracellular structure organization and biogenesis;0.0397919222532879;15227!GO:0048856;anatomical structure development;0.0397919222532879;15227,12160!GO:0046849;bone remodeling;0.0397919222532879;12160!GO:0048771;tissue remodeling;0.043510276184561;12160!GO:0002009;morphogenesis of an epithelium;0.043510276184561;15227!GO:0007275;multicellular organismal development;0.043510276184561;15227,12160! | |||
|ontology_enrichment_celltype= | |||
|ontology_enrichment_disease= | |||
|ontology_enrichment_uberon=UBERON:0005177!1.20e-11!79;UBERON:0002048!4.13e-11!14;UBERON:0000117!4.13e-11!14;UBERON:0000171!4.13e-11!14;UBERON:0000170!4.13e-11!14;UBERON:0005597!4.13e-11!14;UBERON:0000118!4.13e-11!14;UBERON:0004921!6.11e-11!114;UBERON:0004119!1.04e-10!118;UBERON:0000925!1.04e-10!118;UBERON:0006595!1.04e-10!118;UBERON:0001007!2.69e-10!116;UBERON:0001555!2.69e-10!116;UBERON:0007026!2.69e-10!116;UBERON:0009569!3.50e-10!66;UBERON:0000466!3.64e-10!79;UBERON:0005178!6.99e-09!17;UBERON:0005181!6.99e-09!17;UBERON:0002224!6.99e-09!17;UBERON:0000915!6.99e-09!17;UBERON:0008947!6.99e-09!17;UBERON:0003258!6.99e-09!17;UBERON:0002100!8.83e-09!90;UBERON:0005153!2.09e-08!17;UBERON:0000468!2.35e-08!333;UBERON:0005409!6.16e-08!47 | |||
}} |
Latest revision as of 16:16, 17 September 2013
Phase1 CAGE Peaks
Short description | |
---|---|
Mm9::chr10:51310245..51310270,- | p1@Fam162b |
Mm9::chr10:51310279..51310303,- | p2@Fam162b |
Mm9::chr11:8403889..8403913,- | p@chr11:8403889..8403913 - |
Mm9::chr8:123606985..123607053,- | p1@1110050K14Rik |
Mm9::chr8:123607738..123607759,+ | p@chr8:123607738..123607759 + |
Mm9::chr8:123608252..123608268,+ | p1@Foxf1a |
Mm9::chr9:75623162..75623185,+ | p1@Bmp5 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0045198 | establishment of epithelial cell polarity | 0.0176214447361656 |
GO:0030859 | polarized epithelial cell differentiation | 0.0176214447361656 |
GO:0035089 | establishment of apical/basal cell polarity | 0.0176214447361656 |
GO:0045197 | establishment and/or maintenance of epithelial cell polarity | 0.0176214447361656 |
GO:0035088 | establishment and/or maintenance of apical/basal cell polarity | 0.0176214447361656 |
GO:0001738 | morphogenesis of a polarized epithelium | 0.0176214447361656 |
GO:0030010 | establishment of cell polarity | 0.0176214447361656 |
GO:0048566 | embryonic gut development | 0.0176214447361656 |
GO:0048565 | gut development | 0.0216849603820765 |
GO:0007163 | establishment and/or maintenance of cell polarity | 0.0260176733532009 |
GO:0001570 | vasculogenesis | 0.0285761028610465 |
GO:0030855 | epithelial cell differentiation | 0.0308432971942609 |
GO:0048568 | embryonic organ development | 0.0308432971942609 |
GO:0007179 | transforming growth factor beta receptor signaling pathway | 0.0325006961650463 |
GO:0048513 | organ development | 0.0325006961650463 |
GO:0051216 | cartilage development | 0.0325006961650463 |
GO:0030198 | extracellular matrix organization and biogenesis | 0.0363153402358759 |
GO:0030324 | lung development | 0.0370449151759794 |
GO:0030323 | respiratory tube development | 0.0370449151759794 |
GO:0048731 | system development | 0.0371793008965218 |
GO:0048869 | cellular developmental process | 0.0371793008965218 |
GO:0030154 | cell differentiation | 0.0371793008965218 |
GO:0007178 | transmembrane receptor protein serine/threonine kinase signaling pathway | 0.0371793008965218 |
GO:0001503 | ossification | 0.0397919222532879 |
GO:0031214 | biomineral formation | 0.0397919222532879 |
GO:0043062 | extracellular structure organization and biogenesis | 0.0397919222532879 |
GO:0048856 | anatomical structure development | 0.0397919222532879 |
GO:0046849 | bone remodeling | 0.0397919222532879 |
GO:0048771 | tissue remodeling | 0.043510276184561 |
GO:0002009 | morphogenesis of an epithelium | 0.043510276184561 |
GO:0007275 | multicellular organismal development | 0.043510276184561 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
trunk region element | 1.20e-11 | 79 |
lung | 4.13e-11 | 14 |
respiratory tube | 4.13e-11 | 14 |
respiration organ | 4.13e-11 | 14 |
pair of lungs | 4.13e-11 | 14 |
lung primordium | 4.13e-11 | 14 |
lung bud | 4.13e-11 | 14 |
subdivision of digestive tract | 6.11e-11 | 114 |
endoderm-derived structure | 1.04e-10 | 118 |
endoderm | 1.04e-10 | 118 |
presumptive endoderm | 1.04e-10 | 118 |
digestive system | 2.69e-10 | 116 |
digestive tract | 2.69e-10 | 116 |
primitive gut | 2.69e-10 | 116 |
subdivision of trunk | 3.50e-10 | 66 |
immaterial anatomical entity | 3.64e-10 | 79 |
thoracic cavity element | 6.99e-09 | 17 |
thoracic segment organ | 6.99e-09 | 17 |
thoracic cavity | 6.99e-09 | 17 |
thoracic segment of trunk | 6.99e-09 | 17 |
respiratory primordium | 6.99e-09 | 17 |
endoderm of foregut | 6.99e-09 | 17 |
trunk | 8.83e-09 | 90 |
epithelial bud | 2.09e-08 | 17 |
multi-cellular organism | 2.35e-08 | 333 |
gastrointestinal system | 6.16e-08 | 47 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 1.08574 |
MA0004.1 | 0.481116 |
MA0006.1 | 0.837454 |
MA0007.1 | 0.465969 |
MA0009.1 | 0.92425 |
MA0014.1 | 1.02494 |
MA0017.1 | 0.337808 |
MA0019.1 | 0.740036 |
MA0024.1 | 0.880057 |
MA0025.1 | 1.15921 |
MA0027.1 | 2.57545 |
MA0028.1 | 0.321735 |
MA0029.1 | 0.858105 |
MA0030.1 | 0.864739 |
MA0031.1 | 0.828781 |
MA0038.1 | 0.62758 |
MA0040.1 | 0.936879 |
MA0041.1 | 0.404721 |
MA0042.1 | 0.391504 |
MA0043.1 | 1.02178 |
MA0046.1 | 0.960497 |
MA0048.1 | 0.40238 |
MA0050.1 | 0.520357 |
MA0051.1 | 0.636645 |
MA0052.1 | 0.945011 |
MA0055.1 | 0.648475 |
MA0056.1 | 0 |
MA0057.1 | 0.376102 |
MA0058.1 | 0.384683 |
MA0059.1 | 0.397033 |
MA0060.1 | 0.232592 |
MA0061.1 | 0.261749 |
MA0063.1 | 0 |
MA0066.1 | 0.616444 |
MA0067.1 | 1.27078 |
MA0068.1 | 0.771749 |
MA0069.1 | 0.945354 |
MA0070.1 | 0.93557 |
MA0071.1 | 0.519509 |
MA0072.1 | 0.927016 |
MA0073.1 | 0.152496 |
MA0074.1 | 0.580087 |
MA0076.1 | 0.356883 |
MA0077.1 | 0.905143 |
MA0078.1 | 0.670113 |
MA0081.1 | 0.420276 |
MA0083.1 | 1.02098 |
MA0084.1 | 1.59945 |
MA0087.1 | 0.977537 |
MA0088.1 | 1.49527 |
MA0089.1 | 0 |
MA0090.1 | 0.446539 |
MA0091.1 | 0.494398 |
MA0092.1 | 0.446857 |
MA0093.1 | 0.329976 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.568369 |
MA0101.1 | 0.406019 |
MA0103.1 | 0.348572 |
MA0105.1 | 0.162418 |
MA0106.1 | 0.677988 |
MA0107.1 | 0.342432 |
MA0108.2 | 0.763162 |
MA0109.1 | 0 |
MA0111.1 | 0.460823 |
MA0113.1 | 0.649407 |
MA0114.1 | 0.719313 |
MA0115.1 | 1.0246 |
MA0116.1 | 0.311187 |
MA0117.1 | 0.992087 |
MA0119.1 | 1.04809 |
MA0122.1 | 1.01209 |
MA0124.1 | 1.21735 |
MA0125.1 | 1.14291 |
MA0130.1 | 0 |
MA0131.1 | 0.735438 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 1.05845 |
MA0136.1 | 0.600242 |
MA0139.1 | 0.202522 |
MA0140.1 | 0.568252 |
MA0141.1 | 0.964041 |
MA0142.1 | 0.814115 |
MA0143.1 | 0.665982 |
MA0144.1 | 0.72625 |
MA0145.1 | 0.0910975 |
MA0146.1 | 1.57153 |
MA0147.1 | 0.274511 |
MA0148.1 | 1.24416 |
MA0149.1 | 0.411562 |
MA0062.2 | 0.167299 |
MA0035.2 | 0.573016 |
MA0039.2 | 0.219063 |
MA0138.2 | 0.727395 |
MA0002.2 | 0.205289 |
MA0137.2 | 0.957645 |
MA0104.2 | 0.218974 |
MA0047.2 | 0.626803 |
MA0112.2 | 0.0910939 |
MA0065.2 | 0.305574 |
MA0150.1 | 0.465855 |
MA0151.1 | 0 |
MA0152.1 | 0.626912 |
MA0153.1 | 1.07519 |
MA0154.1 | 0.397336 |
MA0155.1 | 0.102995 |
MA0156.1 | 1.67246 |
MA0157.1 | 0.781683 |
MA0158.1 | 0 |
MA0159.1 | 0.776527 |
MA0160.1 | 0.50056 |
MA0161.1 | 0 |
MA0162.1 | 1.71182 |
MA0163.1 | 0.82914 |
MA0164.1 | 0.600609 |
MA0080.2 | 0.343316 |
MA0018.2 | 0.610433 |
MA0099.2 | 0.721008 |
MA0079.2 | 2.82057 |
MA0102.2 | 1.65195 |
MA0258.1 | 0.246285 |
MA0259.1 | 0.26402 |
MA0442.1 | 0 |