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MCL coexpression mm9:2602: Difference between revisions

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{{MCL_coexpression_mm9
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hydroxylation;0.00177505067660111;18453!GO:0031545;peptidyl-proline 4-dioxygenase activity;0.00177505067660111;18453!GO:0018401;peptidyl-proline hydroxylation to 4-hydroxy-L-proline;0.00177505067660111;18453!GO:0019471;4-hydroxyproline metabolic process;0.00177505067660111;18453!GO:0004656;procollagen-proline 4-dioxygenase activity;0.00177505067660111;18453!GO:0018208;peptidyl-proline modification;0.00197227852955679;18453!GO:0019798;procollagen-proline dioxygenase activity;0.00207089245603463;18453!GO:0031543;peptidyl-proline dioxygenase activity;0.00207089245603463;18453!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.00207089245603463;18453!GO:0003756;protein disulfide isomerase activity;0.00207089245603463;18453!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00215157657769831;18453!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.00616337040486496;18453!GO:0045454;cell redox homeostasis;0.00908656893974376;18453!GO:0016860;intramolecular oxidoreductase activity;0.00908656893974376;18453!GO:0046483;heterocycle metabolic process;0.0130170382950748;18453!GO:0006575;amino acid derivative metabolic process;0.0160863967566975;18453!GO:0018193;peptidyl-amino acid modification;0.0161842855807748;18453!GO:0016705;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;0.0205445680162165;18453!GO:0016853;isomerase activity;0.0221176949386011;18453!GO:0005792;microsome;0.0221176949386011;18453!GO:0042598;vesicular fraction;0.0221176949386011;18453!GO:0019725;cellular homeostasis;0.0283739161183965;18453!GO:0006519;amino acid and derivative metabolic process;0.0362727746957618;18453!GO:0042592;homeostatic process;0.0388144414616776;18453!GO:0009308;amine metabolic 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|gostat_on_MCL_coexpression=GO:0019511;peptidyl-proline hydroxylation;0.00177505067660111;18453!GO:0031545;peptidyl-proline 4-dioxygenase activity;0.00177505067660111;18453!GO:0018401;peptidyl-proline hydroxylation to 4-hydroxy-L-proline;0.00177505067660111;18453!GO:0019471;4-hydroxyproline metabolic process;0.00177505067660111;18453!GO:0004656;procollagen-proline 4-dioxygenase activity;0.00177505067660111;18453!GO:0018208;peptidyl-proline modification;0.00197227852955679;18453!GO:0019798;procollagen-proline dioxygenase activity;0.00207089245603463;18453!GO:0031543;peptidyl-proline dioxygenase activity;0.00207089245603463;18453!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.00207089245603463;18453!GO:0003756;protein disulfide isomerase activity;0.00207089245603463;18453!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00215157657769831;18453!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.00616337040486496;18453!GO:0045454;cell redox homeostasis;0.00908656893974376;18453!GO:0016860;intramolecular oxidoreductase activity;0.00908656893974376;18453!GO:0046483;heterocycle metabolic process;0.0130170382950748;18453!GO:0006575;amino acid derivative metabolic process;0.0160863967566975;18453!GO:0018193;peptidyl-amino acid modification;0.0161842855807748;18453!GO:0016705;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;0.0205445680162165;18453!GO:0016853;isomerase activity;0.0221176949386011;18453!GO:0005792;microsome;0.0221176949386011;18453!GO:0042598;vesicular fraction;0.0221176949386011;18453!GO:0019725;cellular homeostasis;0.0283739161183965;18453!GO:0006519;amino acid and derivative metabolic process;0.0362727746957618;18453!GO:0042592;homeostatic process;0.0388144414616776;18453!GO:0009308;amine metabolic process;0.0388144414616776;18453!GO:0006807;nitrogen compound metabolic process;0.0401662108230891;18453!GO:0005624;membrane fraction;0.0488686791212404;18453!
}}

Latest revision as of 18:47, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr10:90545781..90545820,+p1@Ikbip
Mm9::chr10:90545826..90545848,+p2@Ikbip
Mm9::chr11:120434136..120434156,-p2@P4hb


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0019511peptidyl-proline hydroxylation0.00177505067660111
GO:0031545peptidyl-proline 4-dioxygenase activity0.00177505067660111
GO:0018401peptidyl-proline hydroxylation to 4-hydroxy-L-proline0.00177505067660111
GO:00194714-hydroxyproline metabolic process0.00177505067660111
GO:0004656procollagen-proline 4-dioxygenase activity0.00177505067660111
GO:0018208peptidyl-proline modification0.00197227852955679
GO:0019798procollagen-proline dioxygenase activity0.00207089245603463
GO:0031543peptidyl-proline dioxygenase activity0.00207089245603463
GO:0016864intramolecular oxidoreductase activity, transposing S-S bonds0.00207089245603463
GO:0003756protein disulfide isomerase activity0.00207089245603463
GO:0016862intramolecular oxidoreductase activity, interconverting keto- and enol-groups0.00215157657769831
GO:0016706oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors0.00616337040486496
GO:0045454cell redox homeostasis0.00908656893974376
GO:0016860intramolecular oxidoreductase activity0.00908656893974376
GO:0046483heterocycle metabolic process0.0130170382950748
GO:0006575amino acid derivative metabolic process0.0160863967566975
GO:0018193peptidyl-amino acid modification0.0161842855807748
GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen0.0205445680162165
GO:0016853isomerase activity0.0221176949386011
GO:0005792microsome0.0221176949386011
GO:0042598vesicular fraction0.0221176949386011
GO:0019725cellular homeostasis0.0283739161183965
GO:0006519amino acid and derivative metabolic process0.0362727746957618
GO:0042592homeostatic process0.0388144414616776
GO:0009308amine metabolic process0.0388144414616776
GO:0006807nitrogen compound metabolic process0.0401662108230891
GO:0005624membrane fraction0.0488686791212404



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
multi-cellular organism8.86e-07333


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.11.87396
MA0004.10.801718
MA0006.10.60285
MA0007.10.784593
MA0009.11.27673
MA0014.11.33691
MA0017.10.635031
MA0019.11.08369
MA0024.11.23079
MA0025.11.51835
MA0027.12.9431
MA0028.10.61552
MA0029.11.20789
MA0030.11.21482
MA0031.11.17722
MA0038.10.963265
MA0040.11.28983
MA0041.10.714279
MA0042.10.69885
MA0043.11.3775
MA0046.11.31428
MA0048.10.932001
MA0050.10.845669
MA0051.10.973068
MA0052.11.29825
MA0055.10.190475
MA0056.10
MA0057.10.896032
MA0058.10.690848
MA0059.10.705317
MA0060.11.25521
MA0061.10.5406
MA0063.10
MA0066.10.951196
MA0067.11.63197
MA0068.10.343188
MA0069.11.29861
MA0070.11.28847
MA0071.10.844726
MA0072.11.2796
MA0073.10.121346
MA0074.10.911576
MA0076.10.657929
MA0077.11.2569
MA0078.11.0091
MA0081.10.732313
MA0083.11.37668
MA0084.11.96428
MA0087.11.33189
MA0088.10.27999
MA0089.10
MA0090.10.762482
MA0091.10.816659
MA0092.10.762845
MA0093.10.62555
MA0095.10
MA0098.10
MA0100.10.89873
MA0101.10.71579
MA0103.10.647985
MA0105.10.405648
MA0106.11.01755
MA0107.10.640607
MA0108.21.10817
MA0109.10
MA0111.10.778753
MA0113.10.986839
MA0114.10.537669
MA0115.11.38041
MA0116.10.602598
MA0117.11.34691
MA0119.10.716476
MA0122.11.36752
MA0124.11.57762
MA0125.11.5017
MA0130.10
MA0131.11.07881
MA0132.10
MA0133.10
MA0135.11.4152
MA0136.10.933582
MA0139.11.16863
MA0140.10.898603
MA0141.10.671467
MA0142.11.16183
MA0143.11.00467
MA0144.10.541532
MA0145.10.292366
MA0146.11.44443
MA0147.10.556853
MA0148.10.820161
MA0149.10.722227
MA0062.20.412742
MA0035.20.903829
MA0039.26.10909
MA0138.21.07027
MA0002.20.466067
MA0137.20.668025
MA0104.20.48458
MA0047.20.962424
MA0112.20.794478
MA0065.20.292912
MA0150.10.784464
MA0151.10
MA0152.10.962542
MA0153.11.43238
MA0154.10.35067
MA0155.10.312898
MA0156.10.656895
MA0157.11.12772
MA0158.10
MA0159.10.569393
MA0160.10.823568
MA0161.10
MA0162.11.53682
MA0163.10.477233
MA0164.10.933981
MA0080.20.64167
MA0018.20.944669
MA0099.21.06348
MA0079.21.4764
MA0102.22.01714
MA0258.10.520639
MA0259.11.34197
MA0442.10
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