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{{Coexpression_clusters
{{Coexpression_clusters|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.571498051547798,0.70350911749046,0.521418857037502,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1.0754444356266,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0702852779578603,0.33157801473549,0.792349734984542,1.29366894111379,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1.20522624669682,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1.29447091384683,1.34143082547496,0.434701020002233,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1.46450990505843,0.640685378064006,0.72331243662409,0.927616710207603,0,0,0,0,0,0,0,0,0,0,0,0,0,0.929352842471921,0.428105831777209,1.09107799000844,0.132974626782668,0.558193043452778,0.366762561925574,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.344885298375197,0,0.449376834911192,0,0,0,0,0,0,0,0,0,0,0,0,0,0.415649612735124,0.818075152295958,0,0,0,0,0.0322218878591601,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1.06976559384201,1.19921576062375,0,0,0,0,0,0,0,0,0,0.992957796879395,0.758909748641887,0.74325238930376,0.948916753726105,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.549592824056164,0.323472316605661,0.2596110820343,0.108034143853115,0.654453464225937,0.640424737799617,1.03018666421648,0.735194728420072,0,0,0,0,0,0,0,0,0,0,0.392739377694298,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.992710150837532,0.444324042614193,1.03459406728839,0,0,0,0,0,0.203507185739086,0,0,0,0,0,0.0717850907807411,0,0,0.258562315922861,0,0,0,0,0,0,0,0,0.04680465889238,0,0,0,0,0,0,0,0,0,0,0,0,1.66984392167637,1.65736967735508,0,0,0,0,0.291591597755179,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.255893981334376,0,0,0.251068148383664,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.832194294278457,0.0697118989465167,0,0,0,0,0,2.05262161395777,0,0.411933561424686,0.0180901572198087,0,0,0.00843961654883713,0.0334876163089719,0.0840229578243582,0,0,0,0,0,0,0.460228946736334,0,0,0,0,0,0,0,0,0,0,0,0,0.0790650569133411,0,0,0.205380659404915,0,0,0,0,0,0,0,0,0,0,0,0,0.91880291012865,0.751495560257985,0,1.45912664306402,0.0329432353726146,0.0433265804049448,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.231677263595219,0,0.118730395337086,0,0,0,0,0.464642100973416,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.142927500688746,0.145691822538464,0.12291372462026,0,0,0.0832560638586098,0,0,0,0,0,1.1420424773806,0.905579028623721,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.296989076175031,0,0.479678161692362,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.75450984780591,0,0.052217621604872,0,0,0,0,0.333070415914344,0,0,0,0,0,0,0.514086415638705,0,0,0,0,0,0,0,0,0,0,0.674070822324478,1.53116384959798,2.01946108808302,0.498467256755044,0,0,0,0.0895896456213401,0,0,0,0,0.049961086838963,0,0,0,1.3418101863613,0,0,0,0,0,0,0,0.0858467613960337,0,0,0,0,0,0,0,0,0,0,0.352158886104249,0.139783410471546,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1.62753005169345,0.169124272131648,0.710429659490141,0.900857056138814,0,0.0267975841371139,0,2.38886729213003,2.0368179438738,1.91682390357386,1.04601289233091,0.752604986627154,0.295971349506286,0,0,0,1.05351651481173,0.799813092706642,2.01185446706949,0,0.0796420028184954,0|full_id=C1597_tongue_esophagus_tonsil_salivary_Urothelial_uterus_Sebocyte|gostat_on_coexpression_clusters=GO:0001533!cornified envelope!4.97273171415869e-05!6698;3713$GO:0018149!peptide cross-linking!4.97273171415869e-05!6698;3713$GO:0030216!keratinocyte differentiation!4.97273171415869e-05!6698;3713$GO:0031424!keratinization!6.02634697148427e-05!6698;3713$GO:0009913!epidermal cell differentiation!8.0631044571239e-05!6698;3713$GO:0048730!epidermis morphogenesis!8.48377189719717e-05!6698;3713$GO:0048729!tissue morphogenesis!0.000125121378813316!6698;3713$GO:0030674!protein binding, bridging!0.000175335735425548!6698;3713$GO:0008544!epidermis development!0.000343951134968523!6698;3713$GO:0007398!ectoderm development!0.000362182563126683!6698;3713$GO:0018153!isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine!0.000896639637616591!3713$GO:0018262!isopeptide cross-linking!0.000896639637616591!3713$GO:0018199!peptidyl-glutamine modification!0.000896639637616591!3713$GO:0009888!tissue development!0.00112951219199769!6698;3713$GO:0010224!response to UV-B!0.00233098856281588!3713$GO:0018205!peptidyl-lysine modification!0.00327766317991456!3713$GO:0009653!anatomical structure morphogenesis!0.0106752079742699!6698;3713$GO:0009411!response to UV!0.0106752079742699!3713$GO:0048513!organ development!0.0114829820279232!6698;3713$GO:0005856!cytoskeleton!0.0167343191641621!6698;3713$GO:0048731!system development!0.020371068107999!6698;3713$GO:0009416!response to light stimulus!0.0214083531263655!3713$GO:0048869!cellular developmental process!0.0225762523406492!6698;3713$GO:0030154!cell differentiation!0.0225762523406492!6698;3713$GO:0009314!response to radiation!0.0234772039668322!3713$GO:0048856!anatomical structure development!0.0254717113136489!6698;3713$GO:0018193!peptidyl-amino acid modification!0.0260273918288617!3713$GO:0043687!post-translational protein modification!0.0292534242733274!6698;3713$GO:0007275!multicellular organismal development!0.0298465535499906!6698;3713$GO:0009628!response to abiotic stimulus!0.0319013040474445!3713$GO:0005911!intercellular junction!0.0323614306114214!1824$GO:0006464!protein modification process!0.0361448543059518!6698;3713$GO:0007156!homophilic cell adhesion!0.0361448543059518!1824$GO:0005515!protein binding!0.0361448543059518!1824;6698;3713$GO:0043412!biopolymer modification!0.0366866041825411!6698;3713$GO:0043232!intracellular non-membrane-bound organelle!0.0372597586169451!6698;3713$GO:0043228!non-membrane-bound organelle!0.0372597586169451!6698;3713$GO:0032502!developmental 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|full_id=C1597_tongue_esophagus_tonsil_salivary_Urothelial_uterus_Sebocyte
|gostat_on_coexpression_clusters=GO:0001533!cornified envelope!4.97273171415869e-05!6698;3713$GO:0018149!peptide cross-linking!4.97273171415869e-05!6698;3713$GO:0030216!keratinocyte differentiation!4.97273171415869e-05!6698;3713$GO:0031424!keratinization!6.02634697148427e-05!6698;3713$GO:0009913!epidermal cell differentiation!8.0631044571239e-05!6698;3713$GO:0048730!epidermis morphogenesis!8.48377189719717e-05!6698;3713$GO:0048729!tissue morphogenesis!0.000125121378813316!6698;3713$GO:0030674!protein binding, bridging!0.000175335735425548!6698;3713$GO:0008544!epidermis development!0.000343951134968523!6698;3713$GO:0007398!ectoderm development!0.000362182563126683!6698;3713$GO:0018153!isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine!0.000896639637616591!3713$GO:0018262!isopeptide cross-linking!0.000896639637616591!3713$GO:0018199!peptidyl-glutamine modification!0.000896639637616591!3713$GO:0009888!tissue development!0.00112951219199769!6698;3713$GO:0010224!response to UV-B!0.00233098856281588!3713$GO:0018205!peptidyl-lysine modification!0.00327766317991456!3713$GO:0009653!anatomical structure morphogenesis!0.0106752079742699!6698;3713$GO:0009411!response to UV!0.0106752079742699!3713$GO:0048513!organ development!0.0114829820279232!6698;3713$GO:0005856!cytoskeleton!0.0167343191641621!6698;3713$GO:0048731!system development!0.020371068107999!6698;3713$GO:0009416!response to light stimulus!0.0214083531263655!3713$GO:0048869!cellular developmental process!0.0225762523406492!6698;3713$GO:0030154!cell differentiation!0.0225762523406492!6698;3713$GO:0009314!response to radiation!0.0234772039668322!3713$GO:0048856!anatomical structure development!0.0254717113136489!6698;3713$GO:0018193!peptidyl-amino acid modification!0.0260273918288617!3713$GO:0043687!post-translational protein modification!0.0292534242733274!6698;3713$GO:0007275!multicellular organismal development!0.0298465535499906!6698;3713$GO:0009628!response to abiotic stimulus!0.0319013040474445!3713$GO:0005911!intercellular junction!0.0323614306114214!1824$GO:0006464!protein modification process!0.0361448543059518!6698;3713$GO:0007156!homophilic cell adhesion!0.0361448543059518!1824$GO:0005515!protein binding!0.0361448543059518!1824;6698;3713$GO:0043412!biopolymer modification!0.0366866041825411!6698;3713$GO:0043232!intracellular non-membrane-bound organelle!0.0372597586169451!6698;3713$GO:0043228!non-membrane-bound organelle!0.0372597586169451!6698;3713$GO:0032502!developmental process!0.0472438379781197!6698;3713
|id=C1597
}}

Latest revision as of 11:48, 17 September 2013


Full id: C1597_tongue_esophagus_tonsil_salivary_Urothelial_uterus_Sebocyte



Phase1 CAGE Peaks

Hg19::chr10:88780049..88780051,+p1@FAM25A
p1@FAM25B
p1@FAM25C
p1@FAM25G
Hg19::chr18:28682042..28682065,-p1@DSC2
Hg19::chr1:152881014..152881031,+p1@IVL
Hg19::chr1:152956549..152956566,+p1@SPRR1A
Hg19::chr5:175837706..175837718,-p@chr5:175837706..175837718
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0001533cornified envelope4.97273171415869e-05
GO:0018149peptide cross-linking4.97273171415869e-05
GO:0030216keratinocyte differentiation4.97273171415869e-05
GO:0031424keratinization6.02634697148427e-05
GO:0009913epidermal cell differentiation8.0631044571239e-05
GO:0048730epidermis morphogenesis8.48377189719717e-05
GO:0048729tissue morphogenesis0.000125121378813316
GO:0030674protein binding, bridging0.000175335735425548
GO:0008544epidermis development0.000343951134968523
GO:0007398ectoderm development0.000362182563126683
GO:0018153isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine0.000896639637616591
GO:0018262isopeptide cross-linking0.000896639637616591
GO:0018199peptidyl-glutamine modification0.000896639637616591
GO:0009888tissue development0.00112951219199769
GO:0010224response to UV-B0.00233098856281588
GO:0018205peptidyl-lysine modification0.00327766317991456
GO:0009653anatomical structure morphogenesis0.0106752079742699
GO:0009411response to UV0.0106752079742699
GO:0048513organ development0.0114829820279232
GO:0005856cytoskeleton0.0167343191641621
GO:0048731system development0.020371068107999
GO:0009416response to light stimulus0.0214083531263655
GO:0048869cellular developmental process0.0225762523406492
GO:0030154cell differentiation0.0225762523406492
GO:0009314response to radiation0.0234772039668322
GO:0048856anatomical structure development0.0254717113136489
GO:0018193peptidyl-amino acid modification0.0260273918288617
GO:0043687post-translational protein modification0.0292534242733274
GO:0007275multicellular organismal development0.0298465535499906
GO:0009628response to abiotic stimulus0.0319013040474445
GO:0005911intercellular junction0.0323614306114214
GO:0006464protein modification process0.0361448543059518
GO:0007156homophilic cell adhesion0.0361448543059518
GO:0005515protein binding0.0361448543059518
GO:0043412biopolymer modification0.0366866041825411
GO:0043232intracellular non-membrane-bound organelle0.0372597586169451
GO:0043228non-membrane-bound organelle0.0372597586169451
GO:0032502developmental process0.0472438379781197



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Uber Anatomy
Ontology termp-valuen
endoderm-derived structure4.96e-16160
endoderm4.96e-16160
presumptive endoderm4.96e-16160
respiratory system1.56e-1474
orifice5.82e-1236
oral opening3.49e-1122
anterior region of body3.67e-1162
craniocervical region3.67e-1162
surface structure3.09e-1099
urothelium7.50e-105
mouth3.11e-0929
stomodeum3.11e-0929
digestive system3.79e-09145
digestive tract3.79e-09145
primitive gut3.79e-09145
respiratory tract2.43e-0854
head2.95e-0856
transitional epithelium3.99e-086
gingival epithelium4.98e-073
tracheobronchial tree5.35e-0715
lower respiratory tract5.35e-0715
gland of gut5.50e-0710
subdivision of head9.19e-0749
trachea9.30e-077
respiratory airway9.30e-077
Disease
Ontology termp-valuen
squamous cell carcinoma8.27e-0914


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.280184
MA0004.10.626788
MA0006.10.452993
MA0007.10.606704
MA0009.11.11255
MA0014.10.161847
MA0017.10.496101
MA0019.10.784036
MA0024.11.00439
MA0025.11.24931
MA0027.12.73598
MA0028.10.470679
MA0029.11.02437
MA0030.11.01252
MA0031.10.945567
MA0038.10.736268
MA0040.11.03042
MA0041.10.64667
MA0042.10.612397
MA0043.11.11288
MA0046.11.10134
MA0048.10.195817
MA0050.10.613347
MA0051.10.731787
MA0052.11.03442
MA0055.10.288856
MA0056.10
MA0057.10.189508
MA0058.10.523638
MA0059.10.522232
MA0060.10.321781
MA0061.10.791444
MA0063.10
MA0066.10.736721
MA0067.11.43651
MA0068.10.247962
MA0069.11.09737
MA0070.11.08584
MA0071.10.695094
MA0072.11.0812
MA0073.10.00220137
MA0074.10.730989
MA0076.10.540943
MA0077.11.07324
MA0078.10.836493
MA0081.10.522409
MA0083.11.12028
MA0084.11.62584
MA0087.11.07867
MA0088.10.412364
MA0089.10
MA0090.10.556637
MA0091.10.629594
MA0092.10.588959
MA0093.10.456342
MA0095.10
MA0098.10
MA0100.10.750974
MA0101.10.459973
MA0103.11.12656
MA0105.10.520776
MA0106.10.779931
MA0107.10.378225
MA0108.20.94238
MA0109.10
MA0111.11.40074
MA0113.10.797251
MA0114.10.973423
MA0115.11.35895
MA0116.10.382106
MA0117.11.1512
MA0119.10.504689
MA0122.11.17777
MA0124.11.31673
MA0125.11.23103
MA0130.10
MA0131.10.855546
MA0132.10
MA0133.10
MA0135.11.14377
MA0136.10.743749
MA0139.10.277033
MA0140.10.692258
MA0141.10.520334
MA0142.10.912455
MA0143.10.797437
MA0144.10.356507
MA0145.10.868598
MA0146.10.333008
MA0147.10.386018
MA0148.10.653474
MA0149.10.681935
MA0062.20.284987
MA0035.20.691506
MA0039.20.527987
MA0138.20.837782
MA0002.20.30855
MA0137.20.47779
MA0104.20.320919
MA0047.20.767096
MA0112.20.839774
MA0065.21.41695
MA0150.10.550239
MA0151.10
MA0152.10.69926
MA0153.11.21379
MA0154.10.98952
MA0155.10.409315
MA0156.10.480289
MA0157.10.883854
MA0158.10
MA0159.11.77901
MA0160.10.669748
MA0161.10
MA0162.10.21472
MA0163.10.168633
MA0164.10.810347
MA0080.20.456437
MA0018.20.781393
MA0099.21.66926
MA0079.20.146371
MA0102.21.66336
MA0258.10.345771
MA0259.10.395396
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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