Coexpression cluster:C2234: Difference between revisions
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|full_id=C2234_Monocytederived_Dendritic_CD14_Macrophage_CD4_CD14CD16_acute
|id=C2234
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{{Coexpression_clusters | {{Coexpression_clusters|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0,0,0.0477126478678714,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.929892215463955,0.939453280959212,1.06771406816331,0,0,0,0,0,0.262444833400555,1.05349653748261,0.952790995505191,1.03887989931263,1.16271704421986,1.15319797166235,1.21034574128517,0.881294378957879,0.994623194389854,0.878093253655938,0.841513166868245,0.965771622654076,0.89336494809851,1.00042597013467,1.00410699231368,0.828316978269804,0.987040649937771,1.01189588044188,0.746023449222663,0.947974584064448,0.832530465029438,0.822278920160563,1.03479927411655,0.955648296269218,0.958196909944512,0.925567250230469,0.888701142242884,1.01574526265181,1.13139701678982,0.905765222292669,0.803114935848692,0.995027237686497,0.937800328918235,0.937891802408559,1.00031253664199,0.991326785155324,0.865301898279798,1.07233777575701,1.10116936100879,0.941810068712483,1.32486168283694,1.33525624012456,1.17848715781267,0.93364719618844,1.09086472928091,0.936895522062773,0,0.07018719834321,0,0.154341861042433,0,0.197212289927417,0.220381364985783,0,0.00771852916442245,0.200641830559455,0,0.092781878064914,0.163272087601334,0.383192214213463,1.06151805132422,0.985663642903856,1.12877549452765,0.857293692196922,0.912009657734308,0.761611803608781,0.63398933085639,1.00139110882849,0.871392954486308,0.830444039456955,0.909953406071448,0.981718023078275,0.938715720187568,0.994751204681037,0.965573045879295,1.1205926244844,1.14487691286098,1.12488639725537,1.24125714100087,0.975359731389871,0.862972398262654,1.04739428223778,1.06083852833574,0.90873503010325,0.423355588444036,0.524073524849625,0.831456808073212,0.888245477146067,0.856231847327618,0.903388388126992,0.446120916644198,0.0612630850697145,0,0.160569232081516,0,0,0,0,0,0.0293736339771562,0,0,0,0,0.0365629421359175,0.28988387235656,0,0,0.905032201845726,0.733664991767222,0.908479348291944,0.962832223854532,0.885636130507362,0.757572192767554,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.581214274232451,0.815255199587655,0,0,0,0,0,0.182330314034704,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.058052678619159,0.0607877333709642,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0249913395934798,0.0270248130898286,0.106755404617316,0.0219749941377395,0,0,0,0,0,0,0,0.0242804828511018,0,0,0,0.0856043003192711,0,0,0,0,0.120044307824596,0,0.205262792334875,0,0,0.297284871485779,0.169385553164967,0.521220672198064,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1.10101704606284,0.665166815091586,0.967576396550818,0,0,0,0,0,0,0.603984542907533,0.609864035571027,0.499918875048024,0.523760176104352,0.623314462423367,0.0259611465776227,0.0702522028732065,0.262155792373131,0,0.0425075842205678,0.228375713661222,0.0981783143155785,0.09665351272214,0.0785711816082655,0.0585508702232369,0,0,0,0.051206238195096,0,0.0497034598730432,0,0,0.106525016469515,0,0,0,0,0,0,0,0,1.09304309303046,1.11701690159046,0.957452774291493,0,0,0,0,0,0,0,0.757029081832689,0.6437262868033,0.725672834185353,0,0,0,0.0627459241303645,0,0.475673668579065,0,0.470119640033332,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1.05466467089122,1.02969737282111,1.03509039936312,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0520636240695665,0,0,0,0,0.043048141145727,0,0,0,0,0.27140454435617,0,0,0,0,0,0,0,0,0,0,0,0.0519372574301261,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0687021194498525,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.114081610908163,0.058606388680655,0,0,0,0.157986552652174,0,0.0164136111166698,0,0,0,0,0,0,0.299312953566444,0,0,0,0,1.03706320047194,0.947664125493176,1.0279643554612,0.948639283985144,0.937566222628812,1.11961423152429,1.04517929156928,1.01050451026253,0,0,0,0.030552775458397,0,0.838051196030929,0,0.201652865601365,0.591511397298565,0.725341431506739,0.405942870908136,0.256352153599155,0.713894410422282,0.755030118638089,0,0.367329952788721,0.145869915250038,0.399928300127012,0.475875580852904,0.589478484530893,0.67088468411813,0.57761755101658,0.616998659751609,0.62663484539163,0.0533344296716605,0.335707784709379,0.427128410039171,0,0,0,0.331699710686779,0,0.497536880612184,0,0.046490866944115,0.101234535406224,0,0,0.225296951675135,0,0,0,0.243596137495721,0.395369167108553,0,0,0.364165086025872,0,0,0,0.477559288667154,0.0926490999255608,0.721904959458693,0,0,0.12184731704697,0.238280904943946,0,0,0.118394496259328,0,0,0,0,0,0,0,0.170961232827935,0,0.0455495587624001,0.0562266902389565,0.0789958067334975,0,0,0.155009784683122,0,0,0,0,0.107157256199878,0,0.185552006688486,0.305766756572264,0.434286558860722,0.436779110017901,0,0,0,0,0.353278744379379,0,0,0,0,0,0.181982876621091,0.103551833417506,0.430512887228219,0.395435513155428,0.473064598376886,0.398884708229302,0.266232776262519,0.251803386779034,0,0,0,0.126325658803801,0.439188277874969,0,0.713358964238698,0,0,0,0,0,0,0,0,0.0994556584182447,0,0,0.310529906536186,0,0,0,0,0.155051772487567,0,0.139824685950746,0,0,0.177581354547698,0,0,0.265167523949611,0,0,0,0,0,0,0,0,0,0,0,0.273411316494059,0.189664758802821,0.0886035244721425,0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regulation of catalytic activity!0.00280566097991554!920;5330$GO:0000746!conjugation!0.00280566097991554!920$GO:0000747!conjugation with cellular fusion!0.00280566097991554!920$GO:0019932!second-messenger-mediated signaling!0.00280566097991554!920;5330$GO:0042289!MHC class II protein binding!0.00745842523517691!920$GO:0050850!positive regulation of calcium-mediated signaling!0.00745842523517691!920$GO:0050790!regulation of catalytic activity!0.00745842523517691!920;5330$GO:0001948!glycoprotein binding!0.00745842523517691!920$GO:0065009!regulation of a molecular function!0.00745842523517691!920;5330$GO:0050848!regulation of calcium-mediated signaling!0.00745842523517691!920$GO:0045058!T cell selection!0.00871738324255253!920$GO:0045086!positive regulation of interleukin-2 biosynthetic process!0.00953192220820685!920$GO:0042101!T cell receptor complex!0.00953192220820685!920$GO:0045076!regulation of interleukin-2 biosynthetic process!0.00953192220820685!920$GO:0007202!phospholipase C activation!0.00953192220820685!5330$GO:0015026!coreceptor activity!0.00953192220820685!920$GO:0042094!interleukin-2 biosynthetic process!0.00953192220820685!920$GO:0001772!immunological synapse!0.00953192220820685!920$GO:0050731!positive regulation of peptidyl-tyrosine phosphorylation!0.00953192220820685!920$GO:0032623!interleukin-2 production!0.0110461033008635!920$GO:0042327!positive regulation of phosphorylation!0.0110461033008635!920$GO:0042287!MHC protein binding!0.0110461033008635!920$GO:0045937!positive regulation of phosphate metabolic process!0.0110461033008635!920$GO:0001934!positive regulation of protein amino acid phosphorylation!0.0110461033008635!920$GO:0033240!positive regulation of amine metabolic process!0.0110461033008635!920$GO:0045764!positive regulation of amino acid metabolic process!0.0110461033008635!920$GO:0050730!regulation of peptidyl-tyrosine phosphorylation!0.0110461033008635!920$GO:0019722!calcium-mediated signaling!0.0128906242346119!920$GO:0042108!positive regulation of cytokine biosynthetic process!0.0128906242346119!920$GO:0050870!positive regulation of T cell activation!0.0128906242346119!920$GO:0030217!T cell differentiation!0.0128906242346119!920$GO:0018108!peptidyl-tyrosine phosphorylation!0.0128906242346119!920$GO:0018212!peptidyl-tyrosine modification!0.0128906242346119!920$GO:0001932!regulation of protein amino acid phosphorylation!0.0128906242346119!920$GO:0004435!phosphoinositide phospholipase C activity!0.0128906242346119!5330$GO:0004434!inositol or phosphatidylinositol phosphodiesterase activity!0.0128906242346119!5330$GO:0033238!regulation of amine metabolic process!0.0128906242346119!920$GO:0006521!regulation of amino acid metabolic process!0.0128906242346119!920$GO:0009897!external side of plasma membrane!0.0135761902533257!920$GO:0051251!positive regulation of lymphocyte activation!0.0135761902533257!920$GO:0045727!positive regulation of translation!0.0137640724414414!920$GO:0007242!intracellular signaling cascade!0.0138868445486009!920;5330$GO:0004629!phospholipase C activity!0.0138868445486009!5330$GO:0050863!regulation of T cell activation!0.0138868445486009!920$GO:0042035!regulation of cytokine biosynthetic process!0.0138868445486009!920$GO:0031328!positive regulation of cellular biosynthetic process!0.0138868445486009!920$GO:0042325!regulation of phosphorylation!0.0140594504035753!920$GO:0030098!lymphocyte differentiation!0.0140594504035753!920$GO:0042089!cytokine biosynthetic process!0.0140594504035753!920$GO:0042107!cytokine metabolic process!0.0140594504035753!920$GO:0051174!regulation of phosphorus metabolic process!0.0140594504035753!920$GO:0019220!regulation of phosphate metabolic process!0.0140594504035753!920$GO:0009891!positive regulation of biosynthetic process!0.0140594504035753!920$GO:0051345!positive regulation of hydrolase activity!0.0147081714237988!5330$GO:0051249!regulation of lymphocyte activation!0.0147081714237988!920$GO:0050865!regulation of cell activation!0.0152049201089264!920$GO:0019901!protein kinase binding!0.0154976632607284!920$GO:0051247!positive regulation of protein metabolic process!0.0155970015631685!920$GO:0007166!cell surface receptor linked signal transduction!0.015608544421815!920;5330$GO:0007200!G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)!0.015608544421815!5330$GO:0002521!leukocyte differentiation!0.0157011280879805!920$GO:0042110!T cell activation!0.0167207294086174!920$GO:0019900!kinase binding!0.0167207294086174!920$GO:0043235!receptor complex!0.0182853325870361!920$GO:0001816!cytokine production!0.0184942205328129!920$GO:0004620!phospholipase activity!0.0191794236901238!5330$GO:0018193!peptidyl-amino acid modification!0.0192101293103155!920$GO:0005201!extracellular matrix structural constituent!0.0192399133725936!920$GO:0048015!phosphoinositide-mediated signaling!0.0198842451852989!5330$GO:0008081!phosphoric diester hydrolase activity!0.0207059383359219!5330$GO:0045860!positive regulation of protein kinase activity!0.0207059383359219!920$GO:0016298!lipase activity!0.0207059383359219!5330$GO:0033674!positive regulation of kinase activity!0.0207059383359219!920$GO:0016042!lipid catabolic process!0.0207059383359219!5330$GO:0051347!positive regulation of transferase activity!0.0207059383359219!920$GO:0009986!cell surface!0.0207059383359219!920$GO:0009967!positive regulation of signal transduction!0.0211259120621586!920$GO:0046649!lymphocyte activation!0.0211270589636876!920$GO:0042803!protein homodimerization activity!0.0212624215466013!920$GO:0030097!hemopoiesis!0.0213943647765682!920$GO:0048534!hemopoietic or lymphoid organ development!0.0227011416197799!920$GO:0045321!leukocyte activation!0.023278481821903!920$GO:0002520!immune system development!0.023278481821903!920$GO:0006417!regulation of translation!0.023278481821903!920$GO:0004091!carboxylesterase activity!0.0233786574867989!5330$GO:0031326!regulation of cellular biosynthetic process!0.0245375569140324!920$GO:0004871!signal transducer activity!0.0245375569140324!920;5330$GO:0060089!molecular transducer activity!0.0245375569140324!920;5330$GO:0001775!cell activation!0.0247871288886715!920$GO:0007169!transmembrane receptor protein tyrosine kinase signaling pathway!0.0247871288886715!920$GO:0006644!phospholipid metabolic process!0.0250539646838414!5330$GO:0009889!regulation of biosynthetic process!0.0250539646838414!920$GO:0045859!regulation of protein kinase activity!0.0270608654844422!920$GO:0043549!regulation of kinase activity!0.0273357959594244!920$GO:0051338!regulation of transferase activity!0.0276048558785031!920$GO:0006643!membrane lipid metabolic process!0.0300711054365039!5330$GO:0051239!regulation of multicellular organismal process!0.0303059335980524!920$GO:0007167!enzyme linked receptor protein signaling pathway!0.0324763465972865!920$GO:0019899!enzyme binding!0.0325660750257327!920$GO:0051336!regulation of hydrolase activity!0.0325660750257327!5330$GO:0019953!sexual reproduction!0.0330799505842489!920$GO:0051704!multi-organism process!0.0346181715556092!920$GO:0042802!identical protein binding!0.0369436518033426!920$GO:0031325!positive regulation of cellular metabolic process!0.0369436518033426!920$GO:0046983!protein dimerization activity!0.0369436518033426!920$GO:0009893!positive regulation of metabolic process!0.0387476195252912!920$GO:0007165!signal transduction!0.0387476195252912!920;5330$GO:0051246!regulation of protein metabolic process!0.0413786854225017!920$GO:0007154!cell communication!0.0444727613318158!920;5330$GO:0006520!amino acid metabolic 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| ||
|full_id=C2234_Monocytederived_Dendritic_CD14_Macrophage_CD4_CD14CD16_acute | |||
|id=C2234 | |||
}} |
Latest revision as of 12:01, 17 September 2013
Full id: C2234_Monocytederived_Dendritic_CD14_Macrophage_CD4_CD14CD16_acute
Phase1 CAGE Peaks
Hg19::chr12:6898674..6898739,+ | p1@CD4 |
Hg19::chr12:6898749..6898763,+ | p2@CD4 |
Hg19::chr12:6927635..6927648,+ | p@chr12:6927635..6927648 + |
Hg19::chr15:40599895..40599916,- | p4@PLCB2 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
No results for this coexpression
Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0043085 | positive regulation of catalytic activity | 0.00280566097991554 |
GO:0000746 | conjugation | 0.00280566097991554 |
GO:0000747 | conjugation with cellular fusion | 0.00280566097991554 |
GO:0019932 | second-messenger-mediated signaling | 0.00280566097991554 |
GO:0042289 | MHC class II protein binding | 0.00745842523517691 |
GO:0050850 | positive regulation of calcium-mediated signaling | 0.00745842523517691 |
GO:0050790 | regulation of catalytic activity | 0.00745842523517691 |
GO:0001948 | glycoprotein binding | 0.00745842523517691 |
GO:0065009 | regulation of a molecular function | 0.00745842523517691 |
GO:0050848 | regulation of calcium-mediated signaling | 0.00745842523517691 |
GO:0045058 | T cell selection | 0.00871738324255253 |
GO:0045086 | positive regulation of interleukin-2 biosynthetic process | 0.00953192220820685 |
GO:0042101 | T cell receptor complex | 0.00953192220820685 |
GO:0045076 | regulation of interleukin-2 biosynthetic process | 0.00953192220820685 |
GO:0007202 | phospholipase C activation | 0.00953192220820685 |
GO:0015026 | coreceptor activity | 0.00953192220820685 |
GO:0042094 | interleukin-2 biosynthetic process | 0.00953192220820685 |
GO:0001772 | immunological synapse | 0.00953192220820685 |
GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | 0.00953192220820685 |
GO:0032623 | interleukin-2 production | 0.0110461033008635 |
GO:0042327 | positive regulation of phosphorylation | 0.0110461033008635 |
GO:0042287 | MHC protein binding | 0.0110461033008635 |
GO:0045937 | positive regulation of phosphate metabolic process | 0.0110461033008635 |
GO:0001934 | positive regulation of protein amino acid phosphorylation | 0.0110461033008635 |
GO:0033240 | positive regulation of amine metabolic process | 0.0110461033008635 |
GO:0045764 | positive regulation of amino acid metabolic process | 0.0110461033008635 |
GO:0050730 | regulation of peptidyl-tyrosine phosphorylation | 0.0110461033008635 |
GO:0019722 | calcium-mediated signaling | 0.0128906242346119 |
GO:0042108 | positive regulation of cytokine biosynthetic process | 0.0128906242346119 |
GO:0050870 | positive regulation of T cell activation | 0.0128906242346119 |
GO:0030217 | T cell differentiation | 0.0128906242346119 |
GO:0018108 | peptidyl-tyrosine phosphorylation | 0.0128906242346119 |
GO:0018212 | peptidyl-tyrosine modification | 0.0128906242346119 |
GO:0001932 | regulation of protein amino acid phosphorylation | 0.0128906242346119 |
GO:0004435 | phosphoinositide phospholipase C activity | 0.0128906242346119 |
GO:0004434 | inositol or phosphatidylinositol phosphodiesterase activity | 0.0128906242346119 |
GO:0033238 | regulation of amine metabolic process | 0.0128906242346119 |
GO:0006521 | regulation of amino acid metabolic process | 0.0128906242346119 |
GO:0009897 | external side of plasma membrane | 0.0135761902533257 |
GO:0051251 | positive regulation of lymphocyte activation | 0.0135761902533257 |
GO:0045727 | positive regulation of translation | 0.0137640724414414 |
GO:0007242 | intracellular signaling cascade | 0.0138868445486009 |
GO:0004629 | phospholipase C activity | 0.0138868445486009 |
GO:0050863 | regulation of T cell activation | 0.0138868445486009 |
GO:0042035 | regulation of cytokine biosynthetic process | 0.0138868445486009 |
GO:0031328 | positive regulation of cellular biosynthetic process | 0.0138868445486009 |
GO:0042325 | regulation of phosphorylation | 0.0140594504035753 |
GO:0030098 | lymphocyte differentiation | 0.0140594504035753 |
GO:0042089 | cytokine biosynthetic process | 0.0140594504035753 |
GO:0042107 | cytokine metabolic process | 0.0140594504035753 |
GO:0051174 | regulation of phosphorus metabolic process | 0.0140594504035753 |
GO:0019220 | regulation of phosphate metabolic process | 0.0140594504035753 |
GO:0009891 | positive regulation of biosynthetic process | 0.0140594504035753 |
GO:0051345 | positive regulation of hydrolase activity | 0.0147081714237988 |
GO:0051249 | regulation of lymphocyte activation | 0.0147081714237988 |
GO:0050865 | regulation of cell activation | 0.0152049201089264 |
GO:0019901 | protein kinase binding | 0.0154976632607284 |
GO:0051247 | positive regulation of protein metabolic process | 0.0155970015631685 |
GO:0007166 | cell surface receptor linked signal transduction | 0.015608544421815 |
GO:0007200 | G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) | 0.015608544421815 |
GO:0002521 | leukocyte differentiation | 0.0157011280879805 |
GO:0042110 | T cell activation | 0.0167207294086174 |
GO:0019900 | kinase binding | 0.0167207294086174 |
GO:0043235 | receptor complex | 0.0182853325870361 |
GO:0001816 | cytokine production | 0.0184942205328129 |
GO:0004620 | phospholipase activity | 0.0191794236901238 |
GO:0018193 | peptidyl-amino acid modification | 0.0192101293103155 |
GO:0005201 | extracellular matrix structural constituent | 0.0192399133725936 |
GO:0048015 | phosphoinositide-mediated signaling | 0.0198842451852989 |
GO:0008081 | phosphoric diester hydrolase activity | 0.0207059383359219 |
GO:0045860 | positive regulation of protein kinase activity | 0.0207059383359219 |
GO:0016298 | lipase activity | 0.0207059383359219 |
GO:0033674 | positive regulation of kinase activity | 0.0207059383359219 |
GO:0016042 | lipid catabolic process | 0.0207059383359219 |
GO:0051347 | positive regulation of transferase activity | 0.0207059383359219 |
GO:0009986 | cell surface | 0.0207059383359219 |
GO:0009967 | positive regulation of signal transduction | 0.0211259120621586 |
GO:0046649 | lymphocyte activation | 0.0211270589636876 |
GO:0042803 | protein homodimerization activity | 0.0212624215466013 |
GO:0030097 | hemopoiesis | 0.0213943647765682 |
GO:0048534 | hemopoietic or lymphoid organ development | 0.0227011416197799 |
GO:0045321 | leukocyte activation | 0.023278481821903 |
GO:0002520 | immune system development | 0.023278481821903 |
GO:0006417 | regulation of translation | 0.023278481821903 |
GO:0004091 | carboxylesterase activity | 0.0233786574867989 |
GO:0031326 | regulation of cellular biosynthetic process | 0.0245375569140324 |
GO:0004871 | signal transducer activity | 0.0245375569140324 |
GO:0060089 | molecular transducer activity | 0.0245375569140324 |
GO:0001775 | cell activation | 0.0247871288886715 |
GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 0.0247871288886715 |
GO:0006644 | phospholipid metabolic process | 0.0250539646838414 |
GO:0009889 | regulation of biosynthetic process | 0.0250539646838414 |
GO:0045859 | regulation of protein kinase activity | 0.0270608654844422 |
GO:0043549 | regulation of kinase activity | 0.0273357959594244 |
GO:0051338 | regulation of transferase activity | 0.0276048558785031 |
GO:0006643 | membrane lipid metabolic process | 0.0300711054365039 |
GO:0051239 | regulation of multicellular organismal process | 0.0303059335980524 |
GO:0007167 | enzyme linked receptor protein signaling pathway | 0.0324763465972865 |
GO:0019899 | enzyme binding | 0.0325660750257327 |
GO:0051336 | regulation of hydrolase activity | 0.0325660750257327 |
GO:0019953 | sexual reproduction | 0.0330799505842489 |
GO:0051704 | multi-organism process | 0.0346181715556092 |
GO:0042802 | identical protein binding | 0.0369436518033426 |
GO:0031325 | positive regulation of cellular metabolic process | 0.0369436518033426 |
GO:0046983 | protein dimerization activity | 0.0369436518033426 |
GO:0009893 | positive regulation of metabolic process | 0.0387476195252912 |
GO:0007165 | signal transduction | 0.0387476195252912 |
GO:0051246 | regulation of protein metabolic process | 0.0413786854225017 |
GO:0007154 | cell communication | 0.0444727613318158 |
GO:0006520 | amino acid metabolic process | 0.0455972927344681 |
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
Ontology term | p-value | n |
---|---|---|
hematopoietic system | 1.21e-51 | 98 |
blood island | 1.21e-51 | 98 |
hemolymphoid system | 1.17e-45 | 108 |
bone marrow | 5.23e-39 | 76 |
immune system | 4.67e-35 | 93 |
bone element | 9.05e-34 | 82 |
skeletal element | 5.70e-28 | 90 |
skeletal system | 9.83e-25 | 100 |
adult organism | 2.36e-21 | 114 |
lateral plate mesoderm | 1.29e-14 | 203 |
blood | 1.65e-11 | 15 |
haemolymphatic fluid | 1.65e-11 | 15 |
organism substance | 1.65e-11 | 15 |
musculoskeletal system | 5.96e-08 | 167 |
connective tissue | 9.68e-07 | 371 |
Ontology term | p-value | n |
---|---|---|
leukemia | 6.08e-07 | 39 |
Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 0.233555 |
MA0004.1 | 0.71247 |
MA0006.1 | 0.532262 |
MA0007.1 | 0.6918 |
MA0009.1 | 1.20602 |
MA0014.1 | 0.524262 |
MA0017.1 | 0.577281 |
MA0019.1 | 0.873355 |
MA0024.1 | 1.09684 |
MA0025.1 | 1.34373 |
MA0027.1 | 2.83281 |
MA0028.1 | 0.550763 |
MA0029.1 | 1.11704 |
MA0030.1 | 1.10506 |
MA0031.1 | 1.03735 |
MA0038.1 | 0.824639 |
MA0040.1 | 1.12314 |
MA0041.1 | 0.732902 |
MA0042.1 | 0.697662 |
MA0043.1 | 1.20635 |
MA0046.1 | 1.19471 |
MA0048.1 | 0.25531 |
MA0050.1 | 0.69864 |
MA0051.1 | 0.820063 |
MA0052.1 | 1.12718 |
MA0055.1 | 0.396851 |
MA0056.1 | 0 |
MA0057.1 | 0.69331 |
MA0058.1 | 0.605914 |
MA0059.1 | 0.604454 |
MA0060.1 | 0.393285 |
MA0061.1 | 0.360128 |
MA0063.1 | 0 |
MA0066.1 | 0.825101 |
MA0067.1 | 1.53181 |
MA0068.1 | 0.313194 |
MA0069.1 | 1.19071 |
MA0070.1 | 1.17908 |
MA0071.1 | 0.782546 |
MA0072.1 | 1.1744 |
MA0073.1 | 0.599068 |
MA0074.1 | 0.819248 |
MA0076.1 | 0.623864 |
MA0077.1 | 1.16637 |
MA0078.1 | 0.926725 |
MA0081.1 | 0.604638 |
MA0083.1 | 1.21381 |
MA0084.1 | 1.72172 |
MA0087.1 | 1.17185 |
MA0088.1 | 0.536981 |
MA0089.1 | 0 |
MA0090.1 | 0.640115 |
MA0091.1 | 1.70187 |
MA0092.1 | 0.673508 |
MA0093.1 | 0.535768 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.83965 |
MA0101.1 | 0.539569 |
MA0103.1 | 0.521546 |
MA0105.1 | 0.232357 |
MA0106.1 | 0.869173 |
MA0107.1 | 0.453492 |
MA0108.2 | 1.03412 |
MA0109.1 | 0 |
MA0111.1 | 0.655276 |
MA0113.1 | 0.886811 |
MA0114.1 | 0.447443 |
MA0115.1 | 1.45393 |
MA0116.1 | 2.9994 |
MA0117.1 | 1.24497 |
MA0119.1 | 0.586221 |
MA0122.1 | 1.27173 |
MA0124.1 | 1.41151 |
MA0125.1 | 1.32534 |
MA0130.1 | 0 |
MA0131.1 | 0.94608 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 1.23748 |
MA0136.1 | 0.832277 |
MA0139.1 | 0.344952 |
MA0140.1 | 0.779643 |
MA0141.1 | 0.602484 |
MA0142.1 | 1.00381 |
MA0143.1 | 0.887001 |
MA0144.1 | 0.430413 |
MA0145.1 | 1.08195 |
MA0146.1 | 1.25938 |
MA0147.1 | 0.46175 |
MA0148.1 | 0.739888 |
MA0149.1 | 1.813 |
MA0062.2 | 0.353589 |
MA0035.2 | 0.778873 |
MA0039.2 | 1.13403 |
MA0138.2 | 0.928035 |
MA0002.2 | 0.98779 |
MA0137.2 | 0.558189 |
MA0104.2 | 0.392359 |
MA0047.2 | 0.856092 |
MA0112.2 | 0.187982 |
MA0065.2 | 0.577908 |
MA0150.1 | 0.633493 |
MA0151.1 | 0 |
MA0152.1 | 0.78681 |
MA0153.1 | 1.30799 |
MA0154.1 | 0.649108 |
MA0155.1 | 1.61785 |
MA0156.1 | 0.560797 |
MA0157.1 | 0.97481 |
MA0158.1 | 0 |
MA0159.1 | 0.462502 |
MA0160.1 | 0.756582 |
MA0161.1 | 0 |
MA0162.1 | 0.0928415 |
MA0163.1 | 1.37853 |
MA0164.1 | 0.90014 |
MA0080.2 | 0.535868 |
MA0018.2 | 0.870662 |
MA0099.2 | 0.7872 |
MA0079.2 | 1.38179 |
MA0102.2 | 1.75932 |
MA0258.1 | 0.418966 |
MA0259.1 | 0.471671 |
MA0442.1 | 0 |
ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data
No analysis results for this cluster
Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data
This analysis result is provided for C0 - C305 clusters.