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{{UBERON
{{UBERON
|id=UBERON:0001255
|alt_id=UBERON:FMA_15900-FMA_7203-MA_0000368-MA_0000380-MIAA_0000118-MIAA_0000119-MIAA_0000122-WBbt_0005775-XAO_0000154-ZFA_0000529
|name=urinary bladder
|anatomical_img_id=FMA:15900
|namespace=
|def="Organ with organ cavity which is continuous proximally with the right and left ureters and distally with the urethra." [FMA:15900, Wikipedia:Urinary_bladder]
|xref=AAO:0000623;;BTO:0001418;;EFO:0000290;;EHDAA:9328;;EHDAA2:0000174;;EMAPA:18321;;EV:0100098;;FMA:15900;;GAID:0000004;;galen:UrinaryBladder;;http://upload.wikimedia.org/wikipedia/commons/thumb/3/30/Urinary_system.svg/200px-Urinary_system.svg.png;;MA:0000380;;MAT:0000122;;MESH:A.05.810.161;;MIAA:0000122;;ncithesaurus:Bladder;;OpenCyc:Mx4rvVjMmZwpEbGdrcN5Y29ycA;;SCTID:302512001;;VHOG:0000740;;XAO:0000154
|is_a=UBERON:0000077;;UBERON:0000489;;UBERON:0002075;;UBERON:0006554
|synonym="bladder" EXACT [];;"excretory canal" BROAD []
|comment=editor note: consider adding a 'bladder' grouping class
|comment=editor note: consider adding a 'bladder' grouping class
|alt_id=UBERON:FMA_15900-FMA_7203-MA_0000368-MA_0000380-MIAA_0000118-MIAA_0000119-MIAA_0000122-WBbt_0005775-XAO_0000154-ZFA_0000529
|disjoint_from=
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="Organ with organ cavity which is continuous proximally with the right and left ureters and distally with the urethra." [FMA:15900, Wikipedia:Urinary_bladder]
|subset=major_organ;;organ_slim;;uberon_slim
|adjacent_to=
|derives_from=
|derives_from=
|develops_from=UBERON:0000164
|develops_from=UBERON:0000164
|disjoint_from=
|has_quality=
|has_quality=
|id=UBERON:0001255
|is_a=UBERON:0000489 ;;UBERON:0002075 ;;UBERON:0004120 ;;UBERON:0006554
|is_obsolete=
|located_in=
|located_in=
|part_of=UBERON:0001556;;UBERON:0002323
|name=urinary bladder
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.obo.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl
|namespace=FANTOM
|is_obsolete=
|obo_creation_date=
|part_of=UBERON:0001556
|preceded_by=
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl;;UBPROP:0000001 "Anatomical structure which consists of a membranous sac used to temporarily store urine until it is excreted from the body.[AAO]" xsd:string
|subset=major_organ;;organ_slim;;uberon_slim
|synonym="bladder" EXACT [];;"excretory canal" BROAD [];;"vesica urinaria" RELATED LATIN [Wikipedia:Urinary_bladder]
|union_of=
|xref=AAO:0000623;;BTO:0001418;;EFO:0000290;;EHDAA2:0000174;;EHDAA:9328;;EMAPA:18321;;EV:0100098;;FMA:15900;;GAID:0000004;;galen:UrinaryBladder;;http://upload.wikimedia.org/wikipedia/commons/3/30/Urinary_system.svg;;http://upload.wikimedia.org/wikipedia/commons/thumb/3/30/Urinary_system.svg/200px-Urinary_system.svg.png;;MA:0000380;;MAT:0000122;;MESH:A.05.810.161;;MIAA:0000122;;ncithesaurus:Bladder;;OpenCyc:Mx4rvVjMmZwpEbGdrcN5Y29ycA;;SCTID:302512001;;VHOG:0000740;;XAO:0000154
}}
}}

Latest revision as of 17:17, 12 September 2014

Name:urinary bladder
Namespace:FANTOM
Definition:"Organ with organ cavity which is continuous proximally with the right and left ureters and distally with the urethra." [FMA:15900, Wikipedia:Urinary_bladder]
Xrefs:
links:

AAO:0000623
BTO:0001418
EFO:0000290
EHDAA2:0000174
EHDAA:9328
EMAPA:18321
EV:0100098
FMA:15900
GAID:0000004
galen:UrinaryBladder
[1]
[ 200px-Urinary_system.svg.png 200px-Urinary_system.svg.png]
MA:0000380
MAT:0000122
MESH:A.05.810.161
MIAA:0000122
ncithesaurus:Bladder
OpenCyc:Mx4rvVjMmZwpEbGdrcN5Y29ycA
SCTID:302512001
VHOG:0000740

XAO:0000154
Synonyms: "bladder" EXACT []
"excretory canal" BROAD []
"vesica urinaria" RELATED LATIN [Wikipedia:Urinary_bladder]
Comments:editor note: consider adding a 'bladder' grouping class
Alt_id: UBERON:FMA_15900-FMA_7203-MA_0000368-MA_0000380-MIAA_0000118-MIAA_0000119-MIAA_0000122-WBbt_0005775-XAO_0000154-ZFA_0000529
Subset: major_organ
organ_slim
uberon_slim

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0000489(cavitated compound organ),UBERON:0002075(viscus),UBERON:0004120(mesoderm-derived structure),UBERON:0006554(urinary system structure)
develops_from:UBERON:0000164(primitive urogenital sinus)
part_of:UBERON:0001556(lower urinary tract)



Children

derives from:FF:0010011 (human bladder - adult sample),FF:0011437 (mouse urinary bladder- adult sample)
part of:UBERON:0001256 (wall of urinary bladder),UBERON:0001259 (mucosa of urinary bladder),CL:0002597 (smooth muscle cell of bladder),UBERON:0004645 (urinary bladder urothelium),CL:1001319 (bladder cell)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology


Human (Homo sapiens)

Mouse (Mus musculus)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001255 (urinary bladder), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data


P-valueFFCPShort description
1.55e-98FFCP PHASE1:Hg19::chr10:5660248..5660254,-#_2c05b9049aa6f1d0b902d7807dc6f71dp2@ENST00000427341
1.55e-98FFCP PHASE2:Hg19::chr15:101282110..101282113,+#_2c05b9049aa6f1d0b902d7807dc6f71dp@chr15:101282110..101282113, +
1.55e-98FFCP PHASE1:Hg19::chr15:101282110..101282113,+#_2c05b9049aa6f1d0b902d7807dc6f71dp@chr15:101282110..101282113, +
1.55e-98FFCP PHASE2:Hg19::chr5:148796190..148796191,+#_2c05b9049aa6f1d0b902d7807dc6f71dp@chr5:148796190..148796191, +
1.55e-98FFCP PHASE2:Hg19::chr9:125155637..125155639,+#_2c05b9049aa6f1d0b902d7807dc6f71dp@chr9:125155637..125155639, +
1.55e-98FFCP PHASE1:Hg19::chr5:148796190..148796191,+#_2c05b9049aa6f1d0b902d7807dc6f71dp@chr5:148796190..148796191, +
1.55e-98FFCP PHASE1:Hg19::chr9:125155637..125155639,+#_2c05b9049aa6f1d0b902d7807dc6f71dp@chr9:125155637..125155639, +
1.55e-98FFCP PHASE2:Hg19::chr17:3808512..3808513,-#_2c05b9049aa6f1d0b902d7807dc6f71dp@chr17:3808512..3808513, -
1.55e-98FFCP PHASE1:Hg19::chr17:3808512..3808513,-#_2c05b9049aa6f1d0b902d7807dc6f71dp@chr17:3808512..3808513, -
1.55e-98FFCP PHASE2:Hg19::chr1:184801068..184801075,-#_2c05b9049aa6f1d0b902d7807dc6f71dp@chr1:184801068..184801075, -
1.55e-98FFCP PHASE2:Hg19::chr15:99673979..99673984,+#_2c05b9049aa6f1d0b902d7807dc6f71dp27@SYNM
1.55e-98FFCP PHASE2:Hg19::chr10:5660248..5660254,-#_2c05b9049aa6f1d0b902d7807dc6f71dp2@ENST00000427341
1.55e-98FFCP PHASE1:Hg19::chr1:184801068..184801075,-#_2c05b9049aa6f1d0b902d7807dc6f71dp@chr1:184801068..184801075, -
1.55e-98FFCP PHASE1:Hg19::chr15:99673979..99673984,+#_2c05b9049aa6f1d0b902d7807dc6f71dp27@SYNM
3.07e-86FFCP PHASE1:Mm9::chr14:68331267..68331286,-#_666dd11fd0d5bfa7db6780f33bf9e653p@chr14:68331267..68331286, -
3.07e-86FFCP PHASE2:Mm9::chr15:84847637..84847642,+#_666dd11fd0d5bfa7db6780f33bf9e653p3@Upk3a
3.07e-86FFCP PHASE1:Mm9::chr18:44429795..44429800,+#_666dd11fd0d5bfa7db6780f33bf9e653p3@Npy6r
3.07e-86FFCP PHASE2:Mm9::chr14:29722238..29722242,-#_666dd11fd0d5bfa7db6780f33bf9e653p@chr14:29722238..29722242, -
3.07e-86FFCP PHASE2:Mm9::chr15:36485068..36485103,-#_666dd11fd0d5bfa7db6780f33bf9e653p@chr15:36485068..36485103, -
3.07e-86FFCP PHASE1:Mm9::chr19:58073599..58073605,+#_666dd11fd0d5bfa7db6780f33bf9e653p@chr19:58073599..58073605, +
3.07e-86FFCP PHASE1:Mm9::chr19:34791339..34791346,-#_666dd11fd0d5bfa7db6780f33bf9e653p@chr19:34791339..34791346, -
3.07e-86FFCP PHASE2:Mm9::chr11:89595040..89595050,-#_666dd11fd0d5bfa7db6780f33bf9e653p@chr11:89595040..89595050, -
3.07e-86FFCP PHASE1:Mm9::chr10:77520043..77520048,+#_666dd11fd0d5bfa7db6780f33bf9e653p@chr10:77520043..77520048, +
3.07e-86FFCP PHASE1:Mm9::chr15:36485068..36485103,-#_666dd11fd0d5bfa7db6780f33bf9e653p@chr15:36485068..36485103, -
3.07e-86FFCP PHASE2:Mm9::chr12:80992302..80992309,+#_666dd11fd0d5bfa7db6780f33bf9e653p@chr12:80992302..80992309, +
3.07e-86FFCP PHASE2:Mm9::chr17:24078882..24078896,+#_666dd11fd0d5bfa7db6780f33bf9e653p2@Sbp
3.07e-86FFCP PHASE1:Mm9::chr9:109794961..109794968,-#_666dd11fd0d5bfa7db6780f33bf9e653p@chr9:109794961..109794968, -
3.07e-86FFCP PHASE1:Mm9::chr12:80992302..80992309,+#_666dd11fd0d5bfa7db6780f33bf9e653p@chr12:80992302..80992309, +
3.07e-86FFCP PHASE2:Mm9::chr9:109794961..109794968,-#_666dd11fd0d5bfa7db6780f33bf9e653p@chr9:109794961..109794968, -
3.07e-86FFCP PHASE1:Mm9::chr14:29722238..29722242,-#_666dd11fd0d5bfa7db6780f33bf9e653p@chr14:29722238..29722242, -
3.07e-86FFCP PHASE1:Mm9::chr15:84847637..84847642,+#_666dd11fd0d5bfa7db6780f33bf9e653p3@Upk3a
3.07e-86FFCP PHASE2:Mm9::chr19:58073599..58073605,+#_666dd11fd0d5bfa7db6780f33bf9e653p@chr19:58073599..58073605, +
3.07e-86FFCP PHASE1:Mm9::chr11:89595040..89595050,-#_666dd11fd0d5bfa7db6780f33bf9e653p@chr11:89595040..89595050, -
3.07e-86FFCP PHASE1:Mm9::chr9:74005044..74005065,+#_666dd11fd0d5bfa7db6780f33bf9e653p@chr9:74005044..74005065, +
3.07e-86FFCP PHASE2:Mm9::chr18:44429795..44429800,+#_666dd11fd0d5bfa7db6780f33bf9e653p3@Npy6r
3.07e-86FFCP PHASE2:Mm9::chr10:61188929..61188936,+#_666dd11fd0d5bfa7db6780f33bf9e653p@chr10:61188929..61188936, +
3.07e-86FFCP PHASE2:Mm9::chr9:74005044..74005065,+#_666dd11fd0d5bfa7db6780f33bf9e653p@chr9:74005044..74005065, +
3.07e-86FFCP PHASE2:Mm9::chr19:34791339..34791346,-#_666dd11fd0d5bfa7db6780f33bf9e653p@chr19:34791339..34791346, -
3.07e-86FFCP PHASE1:Mm9::chr17:24078882..24078896,+#_666dd11fd0d5bfa7db6780f33bf9e653p2@Sbp
3.07e-86FFCP PHASE2:Mm9::chr10:77520043..77520048,+#_666dd11fd0d5bfa7db6780f33bf9e653p@chr10:77520043..77520048, +
3.07e-86FFCP PHASE1:Mm9::chr7:31388578..31388584,-#_666dd11fd0d5bfa7db6780f33bf9e653p@chr7:31388578..31388584, -
3.07e-86FFCP PHASE2:Mm9::chr14:68331267..68331286,-#_666dd11fd0d5bfa7db6780f33bf9e653p@chr14:68331267..68331286, -
3.07e-86FFCP PHASE2:Mm9::chr7:31388578..31388584,-#_666dd11fd0d5bfa7db6780f33bf9e653p@chr7:31388578..31388584, -
3.07e-86FFCP PHASE1:Mm9::chr10:61188929..61188936,+#_666dd11fd0d5bfa7db6780f33bf9e653p@chr10:61188929..61188936, +
2.74e-50FFCP PHASE1:Hg19::chr6:21666284..21666297,+#_32c08e31778648c4e259c4ac139a6b1dp26@LINC00340
2.74e-50FFCP PHASE1:Hg19::chr6:21383702..21383704,+#_32c08e31778648c4e259c4ac139a6b1dp@chr6:21383702..21383704, +
2.74e-50FFCP PHASE2:Hg19::chr6:21588091..21588098,-#_32c08e31778648c4e259c4ac139a6b1dp@chr6:21588091..21588098, -
2.74e-50FFCP PHASE1:Hg19::chr21:39627877..39627884,+#_32c08e31778648c4e259c4ac139a6b1dp@chr21:39627877..39627884, +
2.74e-50FFCP PHASE2:Hg19::chr3:13992334..13992338,-#_32c08e31778648c4e259c4ac139a6b1dp@chr3:13992334..13992338, -
2.74e-50FFCP PHASE1:Hg19::chr6:21588091..21588098,-#_32c08e31778648c4e259c4ac139a6b1dp@chr6:21588091..21588098, -
2.74e-50FFCP PHASE1:Hg19::chr3:13992334..13992338,-#_32c08e31778648c4e259c4ac139a6b1dp@chr3:13992334..13992338, -
2.74e-50FFCP PHASE2:Hg19::chr16:15850261..15850268,-#_32c08e31778648c4e259c4ac139a6b1dp@chr16:15850261..15850268, -
2.74e-50FFCP PHASE2:Hg19::chr4:186567032..186567041,-#_32c08e31778648c4e259c4ac139a6b1dp@chr4:186567032..186567041, -
2.74e-50FFCP PHASE1:Hg19::chr16:15850261..15850268,-#_32c08e31778648c4e259c4ac139a6b1dp@chr16:15850261..15850268, -
2.74e-50FFCP PHASE2:Hg19::chr6:21664489..21664494,+#_32c08e31778648c4e259c4ac139a6b1dp@chr6:21664489..21664494, +
2.74e-50FFCP PHASE1:Hg19::chr4:186567032..186567041,-#_32c08e31778648c4e259c4ac139a6b1dp@chr4:186567032..186567041, -
2.74e-50FFCP PHASE2:Hg19::chr6:21666284..21666297,+#_32c08e31778648c4e259c4ac139a6b1dp26@LINC00340
2.74e-50FFCP PHASE2:Hg19::chr6:21383702..21383704,+#_32c08e31778648c4e259c4ac139a6b1dp@chr6:21383702..21383704, +
2.74e-50FFCP PHASE2:Hg19::chr21:39627877..39627884,+#_32c08e31778648c4e259c4ac139a6b1dp@chr21:39627877..39627884, +
2.74e-50FFCP PHASE1:Hg19::chr6:21664489..21664494,+#_32c08e31778648c4e259c4ac139a6b1dp@chr6:21664489..21664494, +
4.52e-50FFCP PHASE2:Hg19::chr6:21876977..21876981,+#_e2deef71c9e90bd3a4a86d287f547de3p@chr6:21876977..21876981, +
4.52e-50FFCP PHASE1:Hg19::chr6:21876977..21876981,+#_e2deef71c9e90bd3a4a86d287f547de3p@chr6:21876977..21876981, +
4.52e-50FFCP PHASE2:Hg19::chr1:233430709..233430711,+#_e2deef71c9e90bd3a4a86d287f547de3p@chr1:233430709..233430711, +
4.52e-50FFCP PHASE1:Hg19::chr1:233430709..233430711,+#_e2deef71c9e90bd3a4a86d287f547de3p@chr1:233430709..233430711, +
2.74e-44FFCP PHASE1:Mm9::chr5:87332887..87332894,+#_209c0b79a5bc041797b0c88bca3eb031p@chr5:87332887..87332894, +
2.74e-44FFCP PHASE1:Mm9::chr10:77520022..77520033,+#_209c0b79a5bc041797b0c88bca3eb031p@chr10:77520022..77520033, +
2.74e-44FFCP PHASE2:Mm9::chr2:135755239..135755248,+#_209c0b79a5bc041797b0c88bca3eb031p@chr2:135755239..135755248, +
2.74e-44FFCP PHASE1:Mm9::chr7:31388597..31388604,-#_209c0b79a5bc041797b0c88bca3eb031p@chr7:31388597..31388604, -
2.74e-44FFCP PHASE2:Mm9::chr7:31388597..31388604,-#_209c0b79a5bc041797b0c88bca3eb031p@chr7:31388597..31388604, -
2.74e-44FFCP PHASE2:Mm9::chr16:38783715..38783726,-#_209c0b79a5bc041797b0c88bca3eb031p@chr16:38783715..38783726, -
2.74e-44FFCP PHASE2:Mm9::chr18:44429732..44429737,+#_209c0b79a5bc041797b0c88bca3eb031p2@Npy6r
2.74e-44FFCP PHASE2:Mm9::chr16:44943814..44943823,+#_209c0b79a5bc041797b0c88bca3eb031p4@Cd200r3
2.74e-44FFCP PHASE2:Mm9::chr4:53416435..53416446,-#_209c0b79a5bc041797b0c88bca3eb031p1@ENSMUST00000154377
2.74e-44FFCP PHASE2:Mm9::chr15:36485291..36485294,-#_209c0b79a5bc041797b0c88bca3eb031p2@Snx31
2.74e-44FFCP PHASE1:Mm9::chr9:48260437..48260446,+#_209c0b79a5bc041797b0c88bca3eb031p@chr9:48260437..48260446, +
2.74e-44FFCP PHASE1:Mm9::chr19:34791405..34791413,-#_209c0b79a5bc041797b0c88bca3eb031p@chr19:34791405..34791413, -
2.74e-44FFCP PHASE1:Mm9::chr2:135755239..135755248,+#_209c0b79a5bc041797b0c88bca3eb031p@chr2:135755239..135755248, +
2.74e-44FFCP PHASE1:Mm9::chr16:44943814..44943823,+#_209c0b79a5bc041797b0c88bca3eb031p4@Cd200r3
2.74e-44FFCP PHASE1:Mm9::chr7:31388822..31388831,-#_209c0b79a5bc041797b0c88bca3eb031p@chr7:31388822..31388831, -
2.74e-44FFCP PHASE2:Mm9::chr10:76337225..76337243,-#_209c0b79a5bc041797b0c88bca3eb031p@chr10:76337225..76337243, -
2.74e-44FFCP PHASE1:Mm9::chr16:34922180..34922189,+#_209c0b79a5bc041797b0c88bca3eb031p@chr16:34922180..34922189, +
2.74e-44FFCP PHASE2:Mm9::chr7:31388822..31388831,-#_209c0b79a5bc041797b0c88bca3eb031p@chr7:31388822..31388831, -
2.74e-44FFCP PHASE1:Mm9::chr16:38783715..38783726,-#_209c0b79a5bc041797b0c88bca3eb031p@chr16:38783715..38783726, -
2.74e-44FFCP PHASE2:Mm9::chr4:117650200..117650211,+#_209c0b79a5bc041797b0c88bca3eb031p@chr4:117650200..117650211, +
2.74e-44FFCP PHASE1:Mm9::chr15:36485291..36485294,-#_209c0b79a5bc041797b0c88bca3eb031p2@Snx31
2.74e-44FFCP PHASE1:Mm9::chr7:31390216..31390224,-#_209c0b79a5bc041797b0c88bca3eb031p@chr7:31390216..31390224, -
2.74e-44FFCP PHASE2:Mm9::chr7:31390216..31390224,-#_209c0b79a5bc041797b0c88bca3eb031p@chr7:31390216..31390224, -
2.74e-44FFCP PHASE1:Mm9::chr18:44429732..44429737,+#_209c0b79a5bc041797b0c88bca3eb031p2@Npy6r
2.74e-44FFCP PHASE1:Mm9::chr10:76337225..76337243,-#_209c0b79a5bc041797b0c88bca3eb031p@chr10:76337225..76337243, -
2.74e-44FFCP PHASE1:Mm9::chr2:35519156..35519171,+#_209c0b79a5bc041797b0c88bca3eb031p@chr2:35519156..35519171, +
2.74e-44FFCP PHASE1:Mm9::chr5:92827077..92827083,+#_209c0b79a5bc041797b0c88bca3eb031p@chr5:92827077..92827083, +
2.74e-44FFCP PHASE2:Mm9::chr2:35519156..35519171,+#_209c0b79a5bc041797b0c88bca3eb031p@chr2:35519156..35519171, +
2.74e-44FFCP PHASE2:Mm9::chr10:77520022..77520033,+#_209c0b79a5bc041797b0c88bca3eb031p@chr10:77520022..77520033, +
2.74e-44FFCP PHASE2:Mm9::chr4:41154091..41154099,-#_209c0b79a5bc041797b0c88bca3eb031p@chr4:41154091..41154099, -
2.74e-44FFCP PHASE2:Mm9::chr16:34922180..34922189,+#_209c0b79a5bc041797b0c88bca3eb031p@chr16:34922180..34922189, +
2.74e-44FFCP PHASE1:Mm9::chr7:31388537..31388547,-#_209c0b79a5bc041797b0c88bca3eb031p@chr7:31388537..31388547, -
2.74e-44FFCP PHASE2:Mm9::chr7:31388537..31388547,-#_209c0b79a5bc041797b0c88bca3eb031p@chr7:31388537..31388547, -
2.74e-44FFCP PHASE1:Mm9::chr4:53416435..53416446,-#_209c0b79a5bc041797b0c88bca3eb031p1@ENSMUST00000154377
2.74e-44FFCP PHASE2:Mm9::chr5:92827077..92827083,+#_209c0b79a5bc041797b0c88bca3eb031p@chr5:92827077..92827083, +
2.74e-44FFCP PHASE1:Mm9::chr7:31391935..31391967,+#_209c0b79a5bc041797b0c88bca3eb031p@chr7:31391935..31391967, +










Property "Property value" (as page type) with input value "UBPROP:0000001 "Anatomical structure which consists of a membranous sac used to temporarily store urine until it is excreted from the body.[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.