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{{UBERON
{{UBERON
|id=UBERON:0001820
|alt_id=UBERON:FMA_59152-MA_0000150
|name=sweat gland
|namespace=
|def="Sweat glands are exocrine glands, found in the skin of all mammal species, that are used for body temperature regulation. In humans a system of apocrine - and merocrine sweat glands is the main method of cooling. Many other mammals rely on panting or other means as a primary source of cooling, but still use sweat glands to aid in body temperature regulation. Sweat also serves a purpose of increasing friction on the palms of hands or the pads of paws. Both apocrine and merocrine sweat glands contain myoepithelial cells (from Greek myo-, 'muscle'), specialized epithelial cells located between the gland cells and the underlying basal lamina. Myoepithelial cell contractions squeeze the gland and discharge the accumulated secretions. The secretory activities of the gland cells and the contractions of myoepithelial cells are controlled by both the autonomic nervous system and by the circulating hormones. Additionally, ceruminous glands, which produce ear wax, and mammary glands, which produce milk, are frequently considered to be modified sweat glands. [WP,unvetted]." [Wikipedia:Sweat_gland]
|xref=BTO:0001331;;EV:0100160;;FMA:59152;;GAID:943;;http://upload.wikimedia.org/wikipedia/commons/6/6d/Skin.svg;;http://upload.wikimedia.org/wikipedia/commons/thumb/6/6d/Skin.svg/200px-Skin.svg.png;;MA:0000150;;MESH:A.10.336.899;;ncithesaurus:Sweat_Gland;;OpenCyc:Mx4rvVjx15wpEbGdrcN5Y29ycA;;SCTID:361700009;;VHOG:0001467
|is_a=UBERON:0002365;;UBERON:0007771
|synonym="glandula sudorifera" RELATED [BTO:0001331];;"sudoriferous gland" RELATED [BTO:0001331];;"sudoriparous gland" RELATED [BTO:0001331]
|comment=todo - check if all sweat glands are epidermal - see EMAPA:29743
|comment=todo - check if all sweat glands are epidermal - see EMAPA:29743
|alt_id=UBERON:FMA_59152-MA_0000150
|disjoint_from=
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="Sweat glands are exocrine glands, found in the skin of all mammal species, that are used for body temperature regulation. In humans a system of apocrine - and merocrine sweat glands is the main method of cooling. Many other mammals rely on panting or other means as a primary source of cooling, but still use sweat glands to aid in body temperature regulation. Sweat also serves a purpose of increasing friction on the palms of hands or the pads of paws. Both apocrine and merocrine sweat glands contain myoepithelial cells (from Greek myo-, 'muscle'), specialized epithelial cells located between the gland cells and the underlying basal lamina. Myoepithelial cell contractions squeeze the gland and discharge the accumulated secretions. The secretory activities of the gland cells and the contractions of myoepithelial cells are controlled by both the autonomic nervous system and by the circulating hormones. Additionally, ceruminous glands, which produce ear wax, and mammary glands, which produce milk, are frequently considered to be modified sweat glands. [WP,unvetted]." [Wikipedia:Sweat_gland]
|subset=organ_slim;;uberon_slim
|derives_from=
|derives_from=
|develops_from=UBERON:0005089
|develops_from=UBERON:0005089
|disjoint_from=
|has_quality=
|has_quality=
|id=UBERON:0001820
|is_a=UBERON:0002365 ;;UBERON:0007771
|is_obsolete=
|located_in=
|located_in=
|name=sweat gland
|namespace=
|obo_creation_date=
|part_of=UBERON:0001003
|part_of=UBERON:0001003
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl
|is_obsolete=
|subset=organ_slim;;uberon_slim
|preceded_by=
|synonym="glandula sudorifera" RELATED [BTO:0001331];;"sudoriferous gland" RELATED [BTO:0001331];;"sudoriparous gland" RELATED [BTO:0001331]
|union_of=
|xref=BTO:0001331;;EV:0100160;;FMA:59152;;GAID:943;;http://upload.wikimedia.org/wikipedia/commons/6/6d/Skin.svg;;http://upload.wikimedia.org/wikipedia/commons/thumb/6/6d/Skin.svg/200px-Skin.svg.png;;MA:0000150;;MESH:A.10.336.899;;ncithesaurus:Sweat_Gland;;OpenCyc:Mx4rvVjx15wpEbGdrcN5Y29ycA;;SCTID:361700009;;VHOG:0001467
}}
}}

Revision as of 11:05, 12 September 2014

Name:sweat gland
Definition:"Sweat glands are exocrine glands, found in the skin of all mammal species, that are used for body temperature regulation. In humans a system of apocrine - and merocrine sweat glands is the main method of cooling. Many other mammals rely on panting or other means as a primary source of cooling, but still use sweat glands to aid in body temperature regulation. Sweat also serves a purpose of increasing friction on the palms of hands or the pads of paws. Both apocrine and merocrine sweat glands contain myoepithelial cells (from Greek myo-, 'muscle'), specialized epithelial cells located between the gland cells and the underlying basal lamina. Myoepithelial cell contractions squeeze the gland and discharge the accumulated secretions. The secretory activities of the gland cells and the contractions of myoepithelial cells are controlled by both the autonomic nervous system and by the circulating hormones. Additionally, ceruminous glands, which produce ear wax, and mammary glands, which produce milk, are frequently considered to be modified sweat glands. [WP,unvetted]." [Wikipedia:Sweat_gland]
Xrefs:
links:

BTO:0001331
EV:0100160
FMA:59152
GAID:943
[1]
[ 200px-Skin.svg.png 200px-Skin.svg.png]
MA:0000150
MESH:A.10.336.899
ncithesaurus:Sweat_Gland
OpenCyc:Mx4rvVjx15wpEbGdrcN5Y29ycA
SCTID:361700009

VHOG:0001467
Synonyms: "glandula sudorifera" RELATED [BTO:0001331]
"sudoriferous gland" RELATED [BTO:0001331]
"sudoriparous gland" RELATED [BTO:0001331]
Comments:todo - check if all sweat glands are epidermal - see EMAPA:29743
Alt_id: UBERON:FMA_59152-MA_0000150
Subset: organ_slim
uberon_slim

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0002365(exocrine gland),UBERON:0007771(epidermis gland)
develops_from:UBERON:0005089(sweat gland placode)
part_of:UBERON:0001003(skin epidermis)



Children

part of:CL:1000448 (epithelial cell of sweat gland)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001820 (sweat gland), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
1.55e-98FFCP PHASE2:Hg19::chr1:153321274..153321283,-#_c9286bc92a57327cb2e65684653c8e79p2@PGLYRP4
1.55e-98FFCP PHASE1:Hg19::chr1:153321274..153321283,-#_c9286bc92a57327cb2e65684653c8e79p2@PGLYRP4
2.56e-98FFCP PHASE2:Hg19::chrY:7671916..7671924,-#_3e253814abd0bd9b6452b1a4174efec6p@chrY:7671916..7671924, -
2.56e-98FFCP PHASE1:Hg19::chrY:7671916..7671924,-#_3e253814abd0bd9b6452b1a4174efec6p@chrY:7671916..7671924, -
3.49e-79FFCP PHASE1:Hg19::chr17:19702846..19702866,-#_b086a99efdaff5da3db85154d4a16ca6p@chr17:19702846..19702866, -
3.49e-79FFCP PHASE2:Hg19::chr17:19702846..19702866,-#_b086a99efdaff5da3db85154d4a16ca6p@chr17:19702846..19702866, -
5.22e-79FFCP PHASE2:Hg19::chr1:207038965..207038969,+#_5c2aa962bf474727d4dd343d6afc15fbp1@IL20
5.22e-79FFCP PHASE1:Hg19::chr1:207038965..207038969,+#_5c2aa962bf474727d4dd343d6afc15fbp1@IL20
5.53e-66FFCP PHASE1:Hg19::chr6:12577789..12577820,-#_367662138ab3e11d961c62344cd56dc4p@chr6:12577789..12577820, -
5.53e-66FFCP PHASE2:Hg19::chr6:12577789..12577820,-#_367662138ab3e11d961c62344cd56dc4p@chr6:12577789..12577820, -
4.77e-57FFCP PHASE1:Hg19::chr10:118187325..118187332,+#_288317122f9e796fa878fbdecfc83b71p5@PNLIPRP3
4.77e-57FFCP PHASE2:Hg19::chr10:118187325..118187332,+#_288317122f9e796fa878fbdecfc83b71p5@PNLIPRP3
1.13e-56FFCP PHASE2:Hg19::chr9:27524485..27524505,+#_9af2a8bdf8778245f060688781828b79p2@IFNK
1.13e-56FFCP PHASE1:Hg19::chr9:27524485..27524505,+#_9af2a8bdf8778245f060688781828b79p2@IFNK
4.0e-50FFCP PHASE1:Hg19::chr8:22844791..22844808,+#_8240af04fdeaa54a2da9380a87b17d12p16@RHOBTB2
4.0e-50FFCP PHASE2:Hg19::chr8:22844791..22844808,+#_8240af04fdeaa54a2da9380a87b17d12p16@RHOBTB2
4.52e-50FFCP PHASE2:Hg19::chr15:42566576..42566581,+#_3806ec57a4051a139ed82b7da84947afp18@GANC
4.52e-50FFCP PHASE1:Hg19::chr15:42566576..42566581,+#_3806ec57a4051a139ed82b7da84947afp18@GANC
4.52e-50FFCP PHASE1:Hg19::chr12:122430653..122430662,+#_3806ec57a4051a139ed82b7da84947afp@chr12:122430653..122430662, +
4.52e-50FFCP PHASE2:Hg19::chr5:150951045..150951053,-#_3806ec57a4051a139ed82b7da84947afp@chr5:150951045..150951053, -
4.52e-50FFCP PHASE1:Hg19::chr5:150951045..150951053,-#_3806ec57a4051a139ed82b7da84947afp@chr5:150951045..150951053, -
4.52e-50FFCP PHASE2:Hg19::chr12:122430653..122430662,+#_3806ec57a4051a139ed82b7da84947afp@chr12:122430653..122430662, +
5.15e-50FFCP PHASE2:Hg19::chr2:238933920..238933935,+#_69e772d54b36d83331acc554b02b61a1p7@UBE2F
5.15e-50FFCP PHASE1:Hg19::chr2:238933920..238933935,+#_69e772d54b36d83331acc554b02b61a1p7@UBE2F
1.09e-49FFCP PHASE1:Hg19::chr7:121156367..121156370,-#_64a85c81586a04d193f50531da11b29ep@chr7:121156367..121156370, -
1.09e-49FFCP PHASE2:Hg19::chr7:121156367..121156370,-#_64a85c81586a04d193f50531da11b29ep@chr7:121156367..121156370, -
3.19e-45FFCP PHASE1:Hg19::chr18:9538358..9538360,+#_62154b64e30d5656492ea707b35a228ep@chr18:9538358..9538360, +
3.19e-45FFCP PHASE2:Hg19::chr18:9538358..9538360,+#_62154b64e30d5656492ea707b35a228ep@chr18:9538358..9538360, +
9.79e-45FFCP PHASE2:Hg19::chr9:117972180..117972191,+#_bd973449e876971f471bea139972aa4bp@chr9:117972180..117972191, +
9.79e-45FFCP PHASE1:Hg19::chr9:117972180..117972191,+#_bd973449e876971f471bea139972aa4bp@chr9:117972180..117972191, +
1.91e-44FFCP PHASE1:Hg19::chr10:47740297..47740299,+#_4b2c714741526d30894eeeaf5a7633e8p1@FAM25HP
1.91e-44FFCP PHASE2:Hg19::chr10:47740297..47740299,+#_4b2c714741526d30894eeeaf5a7633e8p1@FAM25HP
1.34e-40FFCP PHASE1:Hg19::chr3:189654013..189654016,-#_8861c25d8be7cef9b6088fa424848692p@chr3:189654013..189654016, -
1.34e-40FFCP PHASE2:Hg19::chr7:97984729..97984742,-#_8861c25d8be7cef9b6088fa424848692p14@BAIAP2L1
1.34e-40FFCP PHASE1:Hg19::chr7:97984729..97984742,-#_8861c25d8be7cef9b6088fa424848692p14@BAIAP2L1
1.34e-40FFCP PHASE2:Hg19::chr3:189654013..189654016,-#_8861c25d8be7cef9b6088fa424848692p@chr3:189654013..189654016, -
2.01e-40FFCP PHASE1:Hg19::chr17:38652332..38652344,-#_94b39f8cc2c62402573d5f6fc5826ed2p18@TNS4
2.01e-40FFCP PHASE2:Hg19::chr2:131669803..131669810,+#_94b39f8cc2c62402573d5f6fc5826ed2p@chr2:131669803..131669810, +
2.01e-40FFCP PHASE2:Hg19::chr17:38652332..38652344,-#_94b39f8cc2c62402573d5f6fc5826ed2p18@TNS4
2.01e-40FFCP PHASE1:Hg19::chr2:131669803..131669810,+#_94b39f8cc2c62402573d5f6fc5826ed2p@chr2:131669803..131669810, +
2.46e-40FFCP PHASE2:Hg19::chr9:27524537..27524559,+#_b737cea3f709a8b5a96c0cb31487e974p1@IFNK
2.46e-40FFCP PHASE1:Hg19::chr9:27524537..27524559,+#_b737cea3f709a8b5a96c0cb31487e974p1@IFNK
5.49e-40FFCP PHASE2:Hg19::chr5:134906500..134906526,+#_d080a1b1f6ca3567347f5c14bde60d5ap@chr5:134906500..134906526, +
5.49e-40FFCP PHASE1:Hg19::chr5:134906500..134906526,+#_d080a1b1f6ca3567347f5c14bde60d5ap@chr5:134906500..134906526, +
1.89e-37FFCP PHASE1:Hg19::chr5:167247103..167247112,+#_736d2c1150938219ef54a31d8b578308p@chr5:167247103..167247112, +
1.89e-37FFCP PHASE2:Hg19::chr5:167247103..167247112,+#_736d2c1150938219ef54a31d8b578308p@chr5:167247103..167247112, +
4.73e-37FFCP PHASE2:Hg19::chr5:52619638..52619641,+#_b87ddfe387defabfb345431d8e081da2p@chr5:52619638..52619641, +
4.73e-37FFCP PHASE1:Hg19::chr5:52619638..52619641,+#_b87ddfe387defabfb345431d8e081da2p@chr5:52619638..52619641, +
1.18e-36FFCP PHASE2:Hg19::chr19:44306567..44306574,-#_cd4bbbc3a82fa818bb94f703c65bf4f3p7@LYPD5
1.18e-36FFCP PHASE1:Hg19::chr19:44306567..44306574,-#_cd4bbbc3a82fa818bb94f703c65bf4f3p7@LYPD5
1.42e-36FFCP PHASE2:Hg19::chr14:51955760..51955769,+#_6f87a09f9225c6d124b42e8bd04f842bp29@FRMD6
1.42e-36FFCP PHASE1:Hg19::chr14:51955760..51955769,+#_6f87a09f9225c6d124b42e8bd04f842bp29@FRMD6
1.7e-36FFCP PHASE2:Hg19::chr2:213770576..213770587,+#_645c1846b712ed4b2482e015a23fe5e7p@chr2:213770576..213770587, +
1.7e-36FFCP PHASE1:Hg19::chr2:213770576..213770587,+#_645c1846b712ed4b2482e015a23fe5e7p@chr2:213770576..213770587, +
2.04e-36FFCP PHASE2:Hg19::chr13:30259768..30259777,+#_b1fbc7e46bd0b763c0288de6cdeaa0c1p@chr13:30259768..30259777, +
2.04e-36FFCP PHASE1:Hg19::chr13:30259768..30259777,+#_b1fbc7e46bd0b763c0288de6cdeaa0c1p@chr13:30259768..30259777, +
2.45e-36FFCP PHASE2:Hg19::chr2:62257232..62257274,+#_8406e411475504f56bb49c6ecfdfbf99p@chr2:62257232..62257274, +
2.45e-36FFCP PHASE1:Hg19::chr2:62257232..62257274,+#_8406e411475504f56bb49c6ecfdfbf99p@chr2:62257232..62257274, +
3.61e-34FFCP PHASE2:Hg19::chr5:93905715..93905716,+#_0b5ebe447c4d6dcf23fcbf5273636b16p2@uc003kkq.1
3.61e-34FFCP PHASE1:Hg19::chr5:93905715..93905716,+#_0b5ebe447c4d6dcf23fcbf5273636b16p2@uc003kkq.1
5.04e-34FFCP PHASE2:Hg19::chr16:57954541..57954548,-#_09d259c12f390c61b5ad05689c330147p@chr16:57954541..57954548, -
5.04e-34FFCP PHASE2:Hg19::chr5:64400723..64400730,-#_09d259c12f390c61b5ad05689c330147p@chr5:64400723..64400730, -
5.04e-34FFCP PHASE1:Hg19::chr16:57954541..57954548,-#_09d259c12f390c61b5ad05689c330147p@chr16:57954541..57954548, -
5.04e-34FFCP PHASE1:Hg19::chr5:64400723..64400730,-#_09d259c12f390c61b5ad05689c330147p@chr5:64400723..64400730, -
7.05e-34FFCP PHASE2:Hg19::chr4:87770064..87770069,-#_0fd59efc88be58cf54d177b984d373bbp13@SLC10A6
7.05e-34FFCP PHASE1:Hg19::chr4:87770064..87770069,-#_0fd59efc88be58cf54d177b984d373bbp13@SLC10A6
7.05e-34FFCP PHASE2:Hg19::chr4:44963669..44963674,+#_0fd59efc88be58cf54d177b984d373bbp@chr4:44963669..44963674, +
7.05e-34FFCP PHASE1:Hg19::chr4:44963669..44963674,+#_0fd59efc88be58cf54d177b984d373bbp@chr4:44963669..44963674, +
7.05e-34FFCP PHASE2:Hg19::chr7:17719182..17719193,-#_0fd59efc88be58cf54d177b984d373bbp@chr7:17719182..17719193, -
7.05e-34FFCP PHASE2:Hg19::chr19:1611369..1611372,-#_0fd59efc88be58cf54d177b984d373bbp13@TCF3
7.05e-34FFCP PHASE1:Hg19::chr7:17719182..17719193,-#_0fd59efc88be58cf54d177b984d373bbp@chr7:17719182..17719193, -
7.05e-34FFCP PHASE1:Hg19::chr19:1611369..1611372,-#_0fd59efc88be58cf54d177b984d373bbp13@TCF3
1.17e-33FFCP PHASE1:Hg19::chr12:28125953..28125964,-#_c0076909897908b712f870792ee7695bp17@PTHLH
1.17e-33FFCP PHASE2:Hg19::chr12:28125953..28125964,-#_c0076909897908b712f870792ee7695bp17@PTHLH
1.39e-33FFCP PHASE1:Hg19::chr16:69145093..69145094,+#_0809d46291ec5da3dcf1e79a21dadaadp@chr16:69145093..69145094, +
1.39e-33FFCP PHASE2:Hg19::chr16:69145093..69145094,+#_0809d46291ec5da3dcf1e79a21dadaadp@chr16:69145093..69145094, +
2.29e-33FFCP PHASE1:Hg19::chr11:128812910..128812927,-#_004d35b0b13569c4e2c00d6391fc5b6cp2@TP53AIP1
2.29e-33FFCP PHASE2:Hg19::chr11:128812910..128812927,-#_004d35b0b13569c4e2c00d6391fc5b6cp2@TP53AIP1
7.33e-32FFCP PHASE1:Hg19::chr17:38120375..38120394,+#_a404e190dc681339eef847b1635b7c80p@chr17:38120375..38120394, +
7.33e-32FFCP PHASE2:Hg19::chr17:38120375..38120394,+#_a404e190dc681339eef847b1635b7c80p@chr17:38120375..38120394, +
1.87e-31FFCP PHASE2:Hg19::chr17:60782123..60782133,+#_337f1327cbf1c9da6c034093cf439f61p@chr17:60782123..60782133, +
1.87e-31FFCP PHASE1:Hg19::chr17:60782123..60782133,+#_337f1327cbf1c9da6c034093cf439f61p@chr17:60782123..60782133, +
4.04e-31FFCP PHASE1:Hg19::chr11:72295793..72295812,-#_7bc568c0b4b6cee713537a3ff34d028ep9@PDE2A
4.04e-31FFCP PHASE2:Hg19::chr11:72295793..72295812,-#_7bc568c0b4b6cee713537a3ff34d028ep9@PDE2A
2.22e-29FFCP PHASE2:Hg19::chr21:44957855..44957891,-#_e3b005c3e52f1507c6c66f3d0edf8ec0p@chr21:44957855..44957891, -
2.22e-29FFCP PHASE1:Hg19::chr21:44957855..44957891,-#_e3b005c3e52f1507c6c66f3d0edf8ec0p@chr21:44957855..44957891, -
2.56e-29FFCP PHASE2:Hg19::chr17:80037380..80037391,-#_817b0d2001060eae4c7cb87d2e4ca3b1p6@BC065179
2.56e-29FFCP PHASE1:Hg19::chr17:80037380..80037391,-#_817b0d2001060eae4c7cb87d2e4ca3b1p6@BC065179
3.41e-29FFCP PHASE2:Hg19::chr5:167247213..167247223,+#_9d712d4b31feee0c495866e491ef4190p@chr5:167247213..167247223, +
3.41e-29FFCP PHASE1:Hg19::chr5:167247213..167247223,+#_9d712d4b31feee0c495866e491ef4190p@chr5:167247213..167247223, +
6.06e-29FFCP PHASE2:Hg19::chr11:93754316..93754353,+#_c9a449294f0544257dc9360794a9045fp2@HEPHL1
6.06e-29FFCP PHASE1:Hg19::chr11:93754316..93754353,+#_c9a449294f0544257dc9360794a9045fp2@HEPHL1
8.13e-28FFCP PHASE2:Hg19::chr7:40883521..40883532,+#_f3f875296907791ba0e9b5bb16ae4abap@chr7:40883521..40883532, +
8.13e-28FFCP PHASE1:Hg19::chr7:40883521..40883532,+#_f3f875296907791ba0e9b5bb16ae4abap@chr7:40883521..40883532, +
1.22e-27FFCP PHASE2:Hg19::chr5:111445067..111445085,-#_a854007251a30df34fefd6db5bb06dafp@chr5:111445067..111445085, -
1.22e-27FFCP PHASE1:Hg19::chr5:111445067..111445085,-#_a854007251a30df34fefd6db5bb06dafp@chr5:111445067..111445085, -
1.6e-27FFCP PHASE2:Hg19::chr7:157086249..157086269,-#_c7da856bcc0b3e778adf0b0ad087365dp@chr7:157086249..157086269, -
1.6e-27FFCP PHASE1:Hg19::chr7:157086249..157086269,-#_c7da856bcc0b3e778adf0b0ad087365dp@chr7:157086249..157086269, -
1.6e-27FFCP PHASE2:Hg19::chr1:209601525..209601530,+#_c7da856bcc0b3e778adf0b0ad087365dp@chr1:209601525..209601530, +
1.6e-27FFCP PHASE1:Hg19::chr1:209601525..209601530,+#_c7da856bcc0b3e778adf0b0ad087365dp@chr1:209601525..209601530, +

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