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MCL coexpression mm9:1072: Difference between revisions

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{{MCL_coexpression_mm9
{{MCL_coexpression_mm9|coexpression_dpi_cluster_scores_mean=0.0247400618323704,-0.0800978506353981,-0.0467582074528286,-0.066374913862393,-0.0805597003848339,0.0220336883508873,0.0237477967678951,-0.0373628616455289,-0.11611393054927,-0.068303287026266,-0.0849673190954088,-0.0818714989476911,-0.0588311913239496,-0.0452336426744261,0.0411300171572361,0.0740360776885243,0.0561295778429727,-0.105637367022907,-0.0816949666359406,-0.106291635679329,0.0432573683734952,0.0325846970800584,0.00357901942990993,0.0315466573510082,0.0819398311586321,-0.016278872958501,-0.00981746766720829,0.0139511133626513,0.0501895712906245,0.0143541904075744,-0.00377036845073093,0.10635463628873,0.119469055127851,0.0490326472193819,0.0175179257430456,0.0382790134760035,0.0540786370822784,0.044427498865059,0.0480744543705347,0.00896415291679014,-0.0422988837470824,-0.0541838287586506,0.00923587369970971,0.139557453985726,0.140691885369989,0.10101754956792,0.207695108220214,0.0283702230257187,0.00868711220047609,0.0316025428518893,0.0593375634532024,0.0451005118142029,-0.117339194739224,-0.107383664883459,-0.0915819675631637,0.0898881271470462,0.126321712457876,0.0552120040692564,-0.0321296526008943,-0.0891785421831883,-0.0325898696999347,0.0180580442654009,0.0329526900882767,0.307036526613845,0.288294766087114,0.272048767506336,0.14187282383875,0.186610904880918,-0.0524453035304907,-0.0650098544243018,-0.057045277413389,-0.0213651246841039,-0.0516490211778591,-0.0817266599965053,-0.0739448117445477,-0.044557436914004,-0.0871635930878657,-0.055199525104757,-0.0500102606930239,-0.084783269865006,-0.0798137108628615,-0.083990732811662,-0.044368398501472,-0.0525533345405141,0.00398091198264831,-0.0622827946598491,-0.0326609956615771,-0.0355070194396146,-0.0631868090942196,0.0236387238761021,0.154784638369692,0.08042723588971,-0.127472542557871,-0.101004684946917,-0.0780597093065804,-0.048210622133464,0.0237511958025092,0.0166519619815621,0.085968894305601,0.0252074240694048,-0.0217696187951281,0.0252393171373986,0.043379677521785,0.0599510028800849,-0.0311080082577773,-0.0331507839856279,-0.0622347223284899,0.0542947962845172,0.0291822798787073,0.0457634581717309,0.0684640412013127,0.0164380806261197,0.0218310624823133,0.0363075177344835,0.0227834923473815,0.0106194127615108,1.15575363998076,0.0412718831856004,0.0766927243268335,0.107008186317708,0.0304437983542919,0.0253935543006922,0.0637928468611444,-0.0140258280361224,0.00489665704668526,0.0577270238457885,0.0272257778040667,0.0223867656251003,0.0278833440068998,-0.0385718860663426,-0.0269375895583267,-0.0804099809738363,-0.0279866650561354,-0.0477237627926044,-0.0490399651877959,-0.0421998425808437,0.0742803834372465,0.0559057533801822,0.0591825822613201,0.0464589271127186,0.0196802486756865,0.0253845319817546,0.0315552018908562,0.0495392944145354,0.0536650886626593,0.0360250979299026,0.0398700668559724,0.0598002880219027,-0.0028149071804007,0.0229578404927958,0.00408097395097269,0.0280674394343714,0.0160485221046294,0.0175138008898043,0.032905380693224,0.0430383764322791,-0.00610804444352457,0.0530590098966354,0.044048852279575,0.0221217661712392,0.00634592575154723,-0.000388764446100221,0.0261427210703476,-0.0112006582471874,0.0241388864127683,-0.0301076133587751,0.00188343972838059,0.00204564138375161,0.0260962337520162,-0.0132338616831537,-0.00473365688837544,-0.0198593564431121,0.00279254358036388,0.0180101839433217,-0.0240223232015631,-0.0396251860235039,0.00355161912914285,0.0770469150382805,0.0280162006087942,0.0417252752806054,0.0977218059456818,0.358881890011234,0.597904291224997,0.847127825555186,0.0391259918109398,0.782634736374934,0.679716390007972,0.690892334655726,0.675181801271202,0.006275942365855,0.0473560537041577,0.0182097301327577,0.00900985189925436,0.0136968024456295,0.0174468730721176,0.0753456908595529,0.0731609706237525,0.0571821535246132,0.114085802707921,0.121076634511882,0.191064090009333,0.222851553556346,-0.025355910175354,0.0546213314782096,0.0746905831541774,0.0504870725718771,0.101818293917245,0.141945109803421,0.0703185502715544,0.201820754231975,0.102145755014006,0.0536971709894123,0.0609050522207366,0.126773292736003,0.115223367865765,0.0472718490457943,0.0304585899429836,0.0300930728642334,0.0509162417562347,-0.0035522706496126,0.0142153492680527,0.0288188575324456,0.0171818963672963,0.01255203430621,0.0575095460368767,0.034848171026228,0.0255440841511406,0.0662563210764453,0.0678462195968156,0.0187493352725002,0.0150440579734543,0.0740634201713468,0.187467497752629,0.168594104932858,0.101317752470996,0.0442370800755317,-0.0506753504323372,-0.0644161195585753,0.0400996791190974,0.00569802440895706,0.00860759646877028,-0.0360292619266797,-0.0153870186511476,-0.0341120089072047,-0.0585242236443716,-0.0420074497503534,-0.0139238590641994,-0.0468399161201407,-0.0437421512037204,-0.0490059977960614,0.0835792568762183,0.094003247198105,0.0630066998491716,0.0808320817476787,0.0615617677889947,0.0586316610287043,0.0341414749954659,0.0328527319833794,0.0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expression=GO:0042802;identical protein binding;0.00657390157114121;76524,18826!GO:0031987;locomotion during locomotory behavior;0.00657390157114121;76524!GO:0001891;phagocytic cup;0.00657390157114121;18826!GO:0045851;pH reduction;0.00657390157114121;76524!GO:0051452;cellular pH reduction;0.00657390157114121;76524!GO:0051453;regulation of cellular pH;0.00657390157114121;76524!GO:0007042;lysosomal lumen acidification;0.00657390157114121;76524!GO:0030641;cellular hydrogen ion homeostasis;0.00862777307470345;76524!GO:0045862;positive regulation of proteolysis;0.0115024368688939;76524!GO:0019864;IgG binding;0.0115024368688939;14132!GO:0030004;cellular monovalent inorganic cation homeostasis;0.013143481366302;76524!GO:0055067;monovalent inorganic cation homeostasis;0.013143481366302;76524!GO:0001573;ganglioside metabolic process;0.013143481366302;76524!GO:0005788;endoplasmic reticulum lumen;0.013143481366302;76524!GO:0019865;immunoglobulin binding;0.0137998992205248;14132!GO:0006687;glycosphingolipid metabolic process;0.0143741073271484;76524!GO:0030162;regulation of proteolysis;0.0166073491042501;76524!GO:0051017;actin filament bundle formation;0.0166073491042501;18826!GO:0007040;lysosome organization and biogenesis;0.0174702955590397;76524!GO:0042612;MHC class I protein complex;0.0174702955590397;14132!GO:0006664;glycolipid metabolic process;0.0174702955590397;76524!GO:0006885;regulation of pH;0.0174702955590397;76524!GO:0006022;aminoglycan metabolic process;0.0174702955590397;76524!GO:0030203;glycosaminoglycan metabolic process;0.0174702955590397;76524!GO:0007033;vacuole organization and biogenesis;0.0174702955590397;76524!GO:0006672;ceramide metabolic process;0.0195774227074295;76524!GO:0005884;actin filament;0.0195774227074295;18826!GO:0051015;actin filament binding;0.0196979418924547;18826!GO:0046519;sphingoid metabolic process;0.0198100625757227;76524!GO:0042611;MHC protein complex;0.0206794381373428;14132!GO:0001726;ruffle;0.0251910804746685;18826!GO:0007015;actin filament organization;0.0287009797667726;18826!GO:0006665;sphingolipid metabolic process;0.0292196113910994;76524!GO:0032403;protein complex binding;0.0330742153113077;14132!GO:0019882;antigen processing and presentation;0.0373584336140453;14132!GO:0006996;organelle organization and biogenesis;0.0396637116983314;76524,18826!GO:0008203;cholesterol metabolic process;0.0396637116983314;76524!GO:0016125;sterol metabolic process;0.0417293940792968;76524!GO:0051247;positive regulation of protein metabolic process;0.0417293940792968;76524!GO:0031252;leading edge;0.0435394367539968;18826!GO:0044432;endoplasmic reticulum 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|gostat_on_MCL_coexpression=GO:0042802;identical protein binding;0.00657390157114121;76524,18826!GO:0031987;locomotion during locomotory behavior;0.00657390157114121;76524!GO:0001891;phagocytic cup;0.00657390157114121;18826!GO:0045851;pH reduction;0.00657390157114121;76524!GO:0051452;cellular pH reduction;0.00657390157114121;76524!GO:0051453;regulation of cellular pH;0.00657390157114121;76524!GO:0007042;lysosomal lumen acidification;0.00657390157114121;76524!GO:0030641;cellular hydrogen ion homeostasis;0.00862777307470345;76524!GO:0045862;positive regulation of proteolysis;0.0115024368688939;76524!GO:0019864;IgG binding;0.0115024368688939;14132!GO:0030004;cellular monovalent inorganic cation homeostasis;0.013143481366302;76524!GO:0055067;monovalent inorganic cation homeostasis;0.013143481366302;76524!GO:0001573;ganglioside metabolic process;0.013143481366302;76524!GO:0005788;endoplasmic reticulum lumen;0.013143481366302;76524!GO:0019865;immunoglobulin binding;0.0137998992205248;14132!GO:0006687;glycosphingolipid metabolic process;0.0143741073271484;76524!GO:0030162;regulation of proteolysis;0.0166073491042501;76524!GO:0051017;actin filament bundle formation;0.0166073491042501;18826!GO:0007040;lysosome organization and biogenesis;0.0174702955590397;76524!GO:0042612;MHC class I protein complex;0.0174702955590397;14132!GO:0006664;glycolipid metabolic process;0.0174702955590397;76524!GO:0006885;regulation of pH;0.0174702955590397;76524!GO:0006022;aminoglycan metabolic process;0.0174702955590397;76524!GO:0030203;glycosaminoglycan metabolic process;0.0174702955590397;76524!GO:0007033;vacuole organization and biogenesis;0.0174702955590397;76524!GO:0006672;ceramide metabolic process;0.0195774227074295;76524!GO:0005884;actin filament;0.0195774227074295;18826!GO:0051015;actin filament binding;0.0196979418924547;18826!GO:0046519;sphingoid metabolic process;0.0198100625757227;76524!GO:0042611;MHC protein complex;0.0206794381373428;14132!GO:0001726;ruffle;0.0251910804746685;18826!GO:0007015;actin filament organization;0.0287009797667726;18826!GO:0006665;sphingolipid metabolic process;0.0292196113910994;76524!GO:0032403;protein complex binding;0.0330742153113077;14132!GO:0019882;antigen processing and presentation;0.0373584336140453;14132!GO:0006996;organelle organization and biogenesis;0.0396637116983314;76524,18826!GO:0008203;cholesterol metabolic process;0.0396637116983314;76524!GO:0016125;sterol metabolic process;0.0417293940792968;76524!GO:0051247;positive regulation of protein metabolic process;0.0417293940792968;76524!GO:0031252;leading edge;0.0435394367539968;18826!GO:0044432;endoplasmic reticulum part;0.0447033451764874;76524!
}}

Latest revision as of 16:21, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr11:45669851..45669893,+p@chr11:45669851..45669893
+
Mm9::chr14:75576396..75576412,+p9@Lcp1
Mm9::chr17:24302011..24302034,-p@chr17:24302011..24302034
-
Mm9::chr7:52358439..52358450,-p@chr7:52358439..52358450
-
Mm9::chr7:52358454..52358468,-p@chr7:52358454..52358468
-
Mm9::chr9:108028873..108028890,-p@chr9:108028873..108028890
-
Mm9::chr9:62686574..62686623,+p1@Cln6


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0042802identical protein binding0.00657390157114121
GO:0031987locomotion during locomotory behavior0.00657390157114121
GO:0001891phagocytic cup0.00657390157114121
GO:0045851pH reduction0.00657390157114121
GO:0051452cellular pH reduction0.00657390157114121
GO:0051453regulation of cellular pH0.00657390157114121
GO:0007042lysosomal lumen acidification0.00657390157114121
GO:0030641cellular hydrogen ion homeostasis0.00862777307470345
GO:0045862positive regulation of proteolysis0.0115024368688939
GO:0019864IgG binding0.0115024368688939
GO:0030004cellular monovalent inorganic cation homeostasis0.013143481366302
GO:0055067monovalent inorganic cation homeostasis0.013143481366302
GO:0001573ganglioside metabolic process0.013143481366302
GO:0005788endoplasmic reticulum lumen0.013143481366302
GO:0019865immunoglobulin binding0.0137998992205248
GO:0006687glycosphingolipid metabolic process0.0143741073271484
GO:0030162regulation of proteolysis0.0166073491042501
GO:0051017actin filament bundle formation0.0166073491042501
GO:0007040lysosome organization and biogenesis0.0174702955590397
GO:0042612MHC class I protein complex0.0174702955590397
GO:0006664glycolipid metabolic process0.0174702955590397
GO:0006885regulation of pH0.0174702955590397
GO:0006022aminoglycan metabolic process0.0174702955590397
GO:0030203glycosaminoglycan metabolic process0.0174702955590397
GO:0007033vacuole organization and biogenesis0.0174702955590397
GO:0006672ceramide metabolic process0.0195774227074295
GO:0005884actin filament0.0195774227074295
GO:0051015actin filament binding0.0196979418924547
GO:0046519sphingoid metabolic process0.0198100625757227
GO:0042611MHC protein complex0.0206794381373428
GO:0001726ruffle0.0251910804746685
GO:0007015actin filament organization0.0287009797667726
GO:0006665sphingolipid metabolic process0.0292196113910994
GO:0032403protein complex binding0.0330742153113077
GO:0019882antigen processing and presentation0.0373584336140453
GO:0006996organelle organization and biogenesis0.0396637116983314
GO:0008203cholesterol metabolic process0.0396637116983314
GO:0016125sterol metabolic process0.0417293940792968
GO:0051247positive regulation of protein metabolic process0.0417293940792968
GO:0031252leading edge0.0435394367539968
GO:0044432endoplasmic reticulum part0.0447033451764874



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br><br><br>



TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.79075
MA0004.13.10641
MA0006.10.311391
MA0007.10.465969
MA0009.10.92425
MA0014.10.222567
MA0017.12.43592
MA0019.10.740036
MA0024.10.880057
MA0025.11.15921
MA0027.12.57545
MA0028.10.321735
MA0029.10.858105
MA0030.10.864739
MA0031.10.828781
MA0038.10.62758
MA0040.10.936879
MA0041.10.404721
MA0042.10.391504
MA0043.11.02178
MA0046.12.20556
MA0048.10.128106
MA0050.10.520357
MA0051.10.636645
MA0052.10.945011
MA0055.11.43589
MA0056.10
MA0057.10.376102
MA0058.12.66057
MA0059.10.397033
MA0060.10.232592
MA0061.10.261749
MA0063.10
MA0066.10.616444
MA0067.11.27078
MA0068.10.121435
MA0069.10.945354
MA0070.10.93557
MA0071.10.519509
MA0072.10.927016
MA0073.10.00223012
MA0074.10.580087
MA0076.10.356883
MA0077.10.905143
MA0078.10.670113
MA0081.11.07783
MA0083.11.02098
MA0084.11.59945
MA0087.10.977537
MA0088.10.285759
MA0089.10
MA0090.10.446539
MA0091.10.494398
MA0092.10.446857
MA0093.13.30666
MA0095.10
MA0098.10
MA0100.10.568369
MA0101.10.406019
MA0103.10.348572
MA0105.10.488671
MA0106.10.677988
MA0107.10.342432
MA0108.20.763162
MA0109.10
MA0111.10.460823
MA0113.10.649407
MA0114.12.04376
MA0115.11.0246
MA0116.10.311187
MA0117.10.992087
MA0119.10.40661
MA0122.11.01209
MA0124.11.21735
MA0125.11.14291
MA0130.10
MA0131.10.735438
MA0132.10
MA0133.10
MA0135.17.30596
MA0136.10.600242
MA0139.10.202522
MA0140.11.3943
MA0141.10.368264
MA0142.10.814115
MA0143.10.665982
MA0144.10.72625
MA0145.10.0910975
MA0146.10.264322
MA0147.10.274511
MA0148.10.49752
MA0149.10.411562
MA0062.20.500692
MA0035.20.573016
MA0039.20.0478878
MA0138.20.727395
MA0002.20.205289
MA0137.20.957645
MA0104.20.624968
MA0047.20.626803
MA0112.21.05549
MA0065.21.56466
MA0150.10.465855
MA0151.10
MA0152.10.626912
MA0153.11.07519
MA0154.10.397336
MA0155.10.102995
MA0156.10.356017
MA0157.10.781683
MA0158.10
MA0159.10.776527
MA0160.10.50056
MA0161.10
MA0162.10.0312493
MA0163.10.116706
MA0164.10.600609
MA0080.20.343316
MA0018.20.610433
MA0099.20.721008
MA0079.20.16158
MA0102.21.65195
MA0258.11.27611
MA0259.10.729797
MA0442.10