MCL coexpression mm9:792: Difference between revisions
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{{MCL_coexpression_mm9 | 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complex;0.00580002165270492;232440,68089,14707,11974,66172!GO:0008154;actin polymerization and/or depolymerization;0.00602443029504808;68089,12631!GO:0032991;macromolecular complex;0.00602443029504808;232440,68089,14707,11974,66172!GO:0044446;intracellular organelle part;0.00776976149973157;232440,68089,12631,11974,66172!GO:0044422;organelle part;0.00776976149973157;232440,68089,12631,11974,66172!GO:0030836;positive regulation of actin filament depolymerization;0.0253074409282662;12631!GO:0001842;neural fold formation;0.0299583719443181;12631!GO:0030036;actin cytoskeleton organization and biogenesis;0.0299583719443181;68089,12631!GO:0030029;actin filament-based process;0.0305337940963763;68089,12631!GO:0015629;actin cytoskeleton;0.036334407086668;68089,12631!GO:0051130;positive regulation of cellular component organization and biogenesis;0.0404586405716512;12631!GO:0015991;ATP hydrolysis coupled proton transport;0.0404586405716512;11974!GO:0005885;Arp2/3 protein complex;0.0404586405716512;68089!GO:0003779;actin binding;0.0404586405716512;68089,12631!GO:0015988;energy coupled proton transport, against electrochemical gradient;0.0404586405716512;11974!|ontology_enrichment_celltype=CL:0000219!3.23e-15!54;CL:0002320!4.62e-11!46;CL:0000134!4.62e-11!46;CL:0002371!8.07e-11!118;CL:0000548!1.83e-09!115;CL:0000255!1.83e-09!115;CL:0000988!2.64e-07!32;CL:0002032!2.64e-07!32;CL:0000037!2.64e-07!32;CL:0000566!2.64e-07!32;CL:0000837!2.64e-07!32;CL:0000333!5.97e-07!10;CL:0000095!5.97e-07!10;CL:0000243!5.97e-07!10;CL:0000123!5.97e-07!10;CL:0000125!5.97e-07!10;CL:0000030!5.97e-07!10;CL:0000339!5.97e-07!10|ontology_enrichment_disease=|ontology_enrichment_uberon=UBERON:0002384!4.62e-11!46;UBERON:0002204!3.64e-09!32;UBERON:0002371!4.38e-08!16|tfbs_overrepresentation_for_novel_motifs=0.93395,0.433653,0.879518,0.394491,0.227651,1.05171,0.495658,2.03865,0.154135,0.0330111,0.453212,0.484001,0.449446,0.507558,0.24249,0,0.696644,0.22065,0.134657,0.0703872,0.296085,0.179861,1.26371,0.64218,0.337218,0.534339,0.128175,0.428336,0.268347,0.319094,0.414842,0.796599,0.624261,0.735537,0.242923,0.00999634,1.78391,1.20775,0.559915,0.167387,0.224094,0.419787,0.371854,0.244285,0.812975,0.998423,1.49936,0.443479,0.314152,1.36808,0.679429,0.560572,0.30602,0.937018,0.954342,1.28038,1.39791,0.471658,0.384731,0.512521,0.776777,0.569793,0.492158,0.668331,0.525334,0.708248,1.08987,1.43807,0.772155,1.29123,0.31262,0.151245,0.424998,0.987652,1.22652,0.107966,0.113315,0.607043,0.759798,0.299972,0.152219,0.713779,0.568383,0.14134,0.873141,0.967095,0.439624,0.0965007,0.623015,1.60001,1.15927,0.878077,1.89585,0.657661,0.188213,0.17334,0.14449,0.812053,0.618454,0.0816605,0.210602,0.796322,0.919715,0.680015,0.678976,1.07585,0.737915,0.439611,1.48974,0.297733,0.348012,0.921485,0.301014,0.458194,1.16629,0.222515,0.496288,0.398075,0.697928,0.207304,0.993019,0.647706,0.536114,0.606154,1.22022,0.763454,0.503569,0.802564,1.08836,0.235546,0.90286,1.00644,1.05894,0.527782,1.18781,0.177062,0.951467,0.421136,1.13883,1.96797,1.5682,1.09456,0.547855,0.806961,0.672593,0.420221,0.621266,1.92834,0.364791,0.229209,0.665499,0.369078,0.938577,0.178329,0.526881,1.01974,0.561556,0.253271,0.352329,0.950885,1.1483,0.872292,0.763895,0.914544,0.669337,0.519673,0.602679,0.482466,0.254444|tfbs_overrepresentation_jaspar=MA0003.1;0.458525,MA0004.1;1.02263,MA0006.1;0.238555,MA0007.1;0.38073,MA0009.1;0.82278,MA0014.1;0.433479,MA0017.1;0.726051,MA0019.1;1.551,MA0024.1;0.779446,MA0025.1;1.05446,MA0027.1;2.46647,MA0028.1;2.77501,MA0029.1;0.757957,MA0030.1;0.764448,MA0031.1;0.729293,MA0038.1;0.534262,MA0040.1;0.835181,MA0041.1;0.323687,MA0042.1;0.311486,MA0043.1;0.918718,MA0046.1;0.858391,MA0048.1;0.589612,MA0050.1;0.431976,MA0051.1;0.542972,MA0052.1;0.84317,MA0055.1;0.692644,MA0056.1;0,MA0057.1;0.258928,MA0058.1;2.27565,MA0059.1;0.316585,MA0060.1;0.9744,MA0061.1;0.56663,MA0063.1;0,MA0066.1;0.523573,MA0067.1;2.62093,MA0068.1;0.563625,MA0069.1;0.843506,MA0070.1;0.833895,MA0071.1;0.431174,MA0072.1;0.825495,MA0073.1;0.000250057,MA0074.1;0.488775,MA0076.1;2.9863,MA0077.1;0.804033,MA0078.1;0.575205,MA0081.1;0.338098,MA0083.1;0.917931,MA0084.1;1.49188,MA0087.1;0.87515,MA0088.1;0.413524,MA0089.1;0,MA0090.1;0.362551,MA0091.1;0.407455,MA0092.1;0.362847,MA0093.1;1.30984,MA0095.1;0,MA0098.1;0,MA0100.1;0.477594,MA0101.1;0.324888,MA0103.1;0.272167,MA0105.1;0.35523,MA0106.1;1.42499,MA0107.1;0.73569,MA0108.2;0.665343,MA0109.1;0,MA0111.1;0.375908,MA0113.1;0.555251,MA0114.1;1.06861,MA0115.1;0.921497,MA0116.1;0.238371,MA0117.1;0.88947,MA0119.1;0.325434,MA0122.1;0.909168,MA0124.1;1.11203,MA0125.1;1.03833,MA0130.1;0,MA0131.1;0.638414,MA0132.1;0,MA0133.1;0,MA0135.1;0.954884,MA0136.1;0.508047,MA0139.1;0.143341,MA0140.1;0.477483,MA0141.1;0.29014,MA0142.1;0.714976,MA0143.1;0.571221,MA0144.1;0.195095,MA0145.1;0.200183,MA0146.1;0.77944,MA0147.1;0.205697,MA0148.1;0.410398,MA0149.1;0.330018,MA0062.2;6.35383,MA0035.2;0.482026,MA0039.2;2.7644,MA0138.2;0.630612,MA0002.2;0.877049,MA0137.2;0.783415,MA0104.2;0.476119,MA0047.2;1.32079,MA0112.2;0.200175,MA0065.2;0.0545595,MA0150.1;0.380623,MA0151.1;0,MA0152.1;0.53362,MA0153.1;0.971406,MA0154.1;0.581988,MA0155.1;0.490492,MA0156.1;1.39718,MA0157.1;0.683365,MA0158.1;0,MA0159.1;0.214506,MA0160.1;0.413266,MA0161.1;0,MA0162.1;0.348617,MA0163.1;0.0600297,MA0164.1;0.508398,MA0080.2;0.267388,MA0018.2;0.51781,MA0099.2;0.624421,MA0079.2;0.968591,MA0102.2;1.5442,MA0258.1;0.180934,MA0259.1;0.196451,MA0442.1;0}} | ||
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| |||
| | |||
}} |
Latest revision as of 15:53, 17 September 2013
Phase1 CAGE Peaks
Short description | |
---|---|
Mm9::chr11:70265407..70265452,+ | p1@Med11 |
Mm9::chr17:26813332..26813333,+ | p3@Atp6v0e |
Mm9::chr17:26813335..26813346,+ | p2@Atp6v0e |
Mm9::chr17:26813350..26813411,+ | p1@Atp6v0e |
Mm9::chr19:5490512..5490525,+ | p1@Cfl1 p1@LOC100048522 |
Mm9::chr3:146162814..146162850,+ | p1@Gm13342 p1@Gm15776 p1@Gm4356 p1@Gng5 p1@LOC100048410 |
Mm9::chr5:124928339..124928393,- | p1@Rilpl2 |
Mm9::chr6:113328152..113328185,+ | p1@Arpc4 |
Mm9::chr6:136756784..136756866,+ | p1@H2afj |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0043234 | protein complex | 0.00580002165270492 |
GO:0008154 | actin polymerization and/or depolymerization | 0.00602443029504808 |
GO:0032991 | macromolecular complex | 0.00602443029504808 |
GO:0044446 | intracellular organelle part | 0.00776976149973157 |
GO:0044422 | organelle part | 0.00776976149973157 |
GO:0030836 | positive regulation of actin filament depolymerization | 0.0253074409282662 |
GO:0001842 | neural fold formation | 0.0299583719443181 |
GO:0030036 | actin cytoskeleton organization and biogenesis | 0.0299583719443181 |
GO:0030029 | actin filament-based process | 0.0305337940963763 |
GO:0015629 | actin cytoskeleton | 0.036334407086668 |
GO:0051130 | positive regulation of cellular component organization and biogenesis | 0.0404586405716512 |
GO:0015991 | ATP hydrolysis coupled proton transport | 0.0404586405716512 |
GO:0005885 | Arp2/3 protein complex | 0.0404586405716512 |
GO:0003779 | actin binding | 0.0404586405716512 |
GO:0015988 | energy coupled proton transport, against electrochemical gradient | 0.0404586405716512 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
motile cell | 3.23e-15 | 54 |
connective tissue cell | 4.62e-11 | 46 |
mesenchymal cell | 4.62e-11 | 46 |
somatic cell | 8.07e-11 | 118 |
animal cell | 1.83e-09 | 115 |
eukaryotic cell | 1.83e-09 | 115 |
hematopoietic cell | 2.64e-07 | 32 |
hematopoietic oligopotent progenitor cell | 2.64e-07 | 32 |
hematopoietic stem cell | 2.64e-07 | 32 |
angioblastic mesenchymal cell | 2.64e-07 | 32 |
hematopoietic multipotent progenitor cell | 2.64e-07 | 32 |
migratory neural crest cell | 5.97e-07 | 10 |
neuron associated cell | 5.97e-07 | 10 |
glial cell (sensu Vertebrata) | 5.97e-07 | 10 |
neuron associated cell (sensu Vertebrata) | 5.97e-07 | 10 |
glial cell | 5.97e-07 | 10 |
glioblast | 5.97e-07 | 10 |
glioblast (sensu Vertebrata) | 5.97e-07 | 10 |
Ontology term | p-value | n |
---|---|---|
connective tissue | 4.62e-11 | 46 |
musculoskeletal system | 3.64e-09 | 32 |
bone marrow | 4.38e-08 | 16 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 0.458525 |
MA0004.1 | 1.02263 |
MA0006.1 | 0.238555 |
MA0007.1 | 0.38073 |
MA0009.1 | 0.82278 |
MA0014.1 | 0.433479 |
MA0017.1 | 0.726051 |
MA0019.1 | 1.551 |
MA0024.1 | 0.779446 |
MA0025.1 | 1.05446 |
MA0027.1 | 2.46647 |
MA0028.1 | 2.77501 |
MA0029.1 | 0.757957 |
MA0030.1 | 0.764448 |
MA0031.1 | 0.729293 |
MA0038.1 | 0.534262 |
MA0040.1 | 0.835181 |
MA0041.1 | 0.323687 |
MA0042.1 | 0.311486 |
MA0043.1 | 0.918718 |
MA0046.1 | 0.858391 |
MA0048.1 | 0.589612 |
MA0050.1 | 0.431976 |
MA0051.1 | 0.542972 |
MA0052.1 | 0.84317 |
MA0055.1 | 0.692644 |
MA0056.1 | 0 |
MA0057.1 | 0.258928 |
MA0058.1 | 2.27565 |
MA0059.1 | 0.316585 |
MA0060.1 | 0.9744 |
MA0061.1 | 0.56663 |
MA0063.1 | 0 |
MA0066.1 | 0.523573 |
MA0067.1 | 2.62093 |
MA0068.1 | 0.563625 |
MA0069.1 | 0.843506 |
MA0070.1 | 0.833895 |
MA0071.1 | 0.431174 |
MA0072.1 | 0.825495 |
MA0073.1 | 0.000250057 |
MA0074.1 | 0.488775 |
MA0076.1 | 2.9863 |
MA0077.1 | 0.804033 |
MA0078.1 | 0.575205 |
MA0081.1 | 0.338098 |
MA0083.1 | 0.917931 |
MA0084.1 | 1.49188 |
MA0087.1 | 0.87515 |
MA0088.1 | 0.413524 |
MA0089.1 | 0 |
MA0090.1 | 0.362551 |
MA0091.1 | 0.407455 |
MA0092.1 | 0.362847 |
MA0093.1 | 1.30984 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.477594 |
MA0101.1 | 0.324888 |
MA0103.1 | 0.272167 |
MA0105.1 | 0.35523 |
MA0106.1 | 1.42499 |
MA0107.1 | 0.73569 |
MA0108.2 | 0.665343 |
MA0109.1 | 0 |
MA0111.1 | 0.375908 |
MA0113.1 | 0.555251 |
MA0114.1 | 1.06861 |
MA0115.1 | 0.921497 |
MA0116.1 | 0.238371 |
MA0117.1 | 0.88947 |
MA0119.1 | 0.325434 |
MA0122.1 | 0.909168 |
MA0124.1 | 1.11203 |
MA0125.1 | 1.03833 |
MA0130.1 | 0 |
MA0131.1 | 0.638414 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 0.954884 |
MA0136.1 | 0.508047 |
MA0139.1 | 0.143341 |
MA0140.1 | 0.477483 |
MA0141.1 | 0.29014 |
MA0142.1 | 0.714976 |
MA0143.1 | 0.571221 |
MA0144.1 | 0.195095 |
MA0145.1 | 0.200183 |
MA0146.1 | 0.77944 |
MA0147.1 | 0.205697 |
MA0148.1 | 0.410398 |
MA0149.1 | 0.330018 |
MA0062.2 | 6.35383 |
MA0035.2 | 0.482026 |
MA0039.2 | 2.7644 |
MA0138.2 | 0.630612 |
MA0002.2 | 0.877049 |
MA0137.2 | 0.783415 |
MA0104.2 | 0.476119 |
MA0047.2 | 1.32079 |
MA0112.2 | 0.200175 |
MA0065.2 | 0.0545595 |
MA0150.1 | 0.380623 |
MA0151.1 | 0 |
MA0152.1 | 0.53362 |
MA0153.1 | 0.971406 |
MA0154.1 | 0.581988 |
MA0155.1 | 0.490492 |
MA0156.1 | 1.39718 |
MA0157.1 | 0.683365 |
MA0158.1 | 0 |
MA0159.1 | 0.214506 |
MA0160.1 | 0.413266 |
MA0161.1 | 0 |
MA0162.1 | 0.348617 |
MA0163.1 | 0.0600297 |
MA0164.1 | 0.508398 |
MA0080.2 | 0.267388 |
MA0018.2 | 0.51781 |
MA0099.2 | 0.624421 |
MA0079.2 | 0.968591 |
MA0102.2 | 1.5442 |
MA0258.1 | 0.180934 |
MA0259.1 | 0.196451 |
MA0442.1 | 0 |