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MCL coexpression mm9:714: Difference between revisions

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{{MCL_coexpression_mm9
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extracellular matrix;0.00239169796319844;58859,12306,26561!GO:0007596;blood coagulation;0.00239169796319844;58859,12306!GO:0007599;hemostasis;0.00239169796319844;58859,12306!GO:0050817;coagulation;0.00239169796319844;58859,12306!GO:0050878;regulation of body fluid levels;0.00322337681094783;58859,12306!GO:0042060;wound healing;0.00342353840125252;58859,12306!GO:0042730;fibrinolysis;0.0111526559670423;12306!GO:0030195;negative regulation of blood coagulation;0.0111526559670423;12306!GO:0055102;lipase inhibitor activity;0.0111526559670423;12306!GO:0004859;phospholipase inhibitor activity;0.0111526559670423;12306!GO:0030193;regulation of blood coagulation;0.0111526559670423;12306!GO:0050819;negative regulation of coagulation;0.015331541432823;12306!GO:0009611;response to wounding;0.0197055026113255;58859,12306!GO:0050818;regulation of coagulation;0.0197055026113255;12306!GO:0005641;nuclear envelope lumen;0.0204330967981858;67169!GO:0030199;collagen fibril organization;0.0287183028703937;12306!GO:0005544;calcium-dependent phospholipid binding;0.0292212346136963;12306!GO:0001725;stress fiber;0.0292212346136963;12306!GO:0032432;actin filament bundle;0.0292212346136963;12306!GO:0009605;response to external stimulus;0.0292212346136963;58859,12306!GO:0005624;membrane fraction;0.0292212346136963;67169,12306!GO:0031970;organelle envelope lumen;0.0292212346136963;67169!GO:0005769;early endosome;0.0306060134462106;12306!GO:0000267;cell fraction;0.0325670350830315;67169,12306!GO:0042383;sarcolemma;0.0342599583831768;12306!GO:0016020;membrane;0.0432491869866063;246154,67169,58859,12306,26561!GO:0065008;regulation of biological 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|gostat_on_MCL_coexpression=GO:0005578;proteinaceous extracellular matrix;0.00239169796319844;58859,12306,26561!GO:0007596;blood coagulation;0.00239169796319844;58859,12306!GO:0007599;hemostasis;0.00239169796319844;58859,12306!GO:0050817;coagulation;0.00239169796319844;58859,12306!GO:0050878;regulation of body fluid levels;0.00322337681094783;58859,12306!GO:0042060;wound healing;0.00342353840125252;58859,12306!GO:0042730;fibrinolysis;0.0111526559670423;12306!GO:0030195;negative regulation of blood coagulation;0.0111526559670423;12306!GO:0055102;lipase inhibitor activity;0.0111526559670423;12306!GO:0004859;phospholipase inhibitor activity;0.0111526559670423;12306!GO:0030193;regulation of blood coagulation;0.0111526559670423;12306!GO:0050819;negative regulation of coagulation;0.015331541432823;12306!GO:0009611;response to wounding;0.0197055026113255;58859,12306!GO:0050818;regulation of coagulation;0.0197055026113255;12306!GO:0005641;nuclear envelope lumen;0.0204330967981858;67169!GO:0030199;collagen fibril organization;0.0287183028703937;12306!GO:0005544;calcium-dependent phospholipid binding;0.0292212346136963;12306!GO:0001725;stress fiber;0.0292212346136963;12306!GO:0032432;actin filament bundle;0.0292212346136963;12306!GO:0009605;response to external stimulus;0.0292212346136963;58859,12306!GO:0005624;membrane fraction;0.0292212346136963;67169,12306!GO:0031970;organelle envelope lumen;0.0292212346136963;67169!GO:0005769;early endosome;0.0306060134462106;12306!GO:0000267;cell fraction;0.0325670350830315;67169,12306!GO:0042383;sarcolemma;0.0342599583831768;12306!GO:0016020;membrane;0.0432491869866063;246154,67169,58859,12306,26561!GO:0065008;regulation of biological quality;0.0432491869866063;58859,12306!
|ontology_enrichment_celltype=CL:0000333!6.87e-07!10;CL:0000095!6.87e-07!10;CL:0000243!6.87e-07!10;CL:0000123!6.87e-07!10;CL:0000125!6.87e-07!10;CL:0000030!6.87e-07!10;CL:0000339!6.87e-07!10
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0000464!7.80e-07!57
}}

Latest revision as of 15:46, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr11:70051072..70051102,-p5@0610010K14Rik
Mm9::chr16:4639956..4639978,+p1@Vasn
Mm9::chr19:5474617..5474644,+p2@Efemp2
Mm9::chr19:5474681..5474775,+p1@Efemp2
Mm9::chr19:5474796..5474822,+p4@Efemp2
Mm9::chr19:5476132..5476138,+p@chr19:5476132..5476138
+
Mm9::chr4:155027293..155027345,-p1@Mmp23
Mm9::chr9:110526854..110526862,-p2@Nradd
Mm9::chr9:69301891..69301923,+p2@Anxa2
Mm9::chrX:70740946..70740969,+p@chrX:70740946..70740969
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0005578proteinaceous extracellular matrix0.00239169796319844
GO:0007596blood coagulation0.00239169796319844
GO:0007599hemostasis0.00239169796319844
GO:0050817coagulation0.00239169796319844
GO:0050878regulation of body fluid levels0.00322337681094783
GO:0042060wound healing0.00342353840125252
GO:0042730fibrinolysis0.0111526559670423
GO:0030195negative regulation of blood coagulation0.0111526559670423
GO:0055102lipase inhibitor activity0.0111526559670423
GO:0004859phospholipase inhibitor activity0.0111526559670423
GO:0030193regulation of blood coagulation0.0111526559670423
GO:0050819negative regulation of coagulation0.015331541432823
GO:0009611response to wounding0.0197055026113255
GO:0050818regulation of coagulation0.0197055026113255
GO:0005641nuclear envelope lumen0.0204330967981858
GO:0030199collagen fibril organization0.0287183028703937
GO:0005544calcium-dependent phospholipid binding0.0292212346136963
GO:0001725stress fiber0.0292212346136963
GO:0032432actin filament bundle0.0292212346136963
GO:0009605response to external stimulus0.0292212346136963
GO:0005624membrane fraction0.0292212346136963
GO:0031970organelle envelope lumen0.0292212346136963
GO:0005769early endosome0.0306060134462106
GO:0000267cell fraction0.0325670350830315
GO:0042383sarcolemma0.0342599583831768
GO:0016020membrane0.0432491869866063
GO:0065008regulation of biological quality0.0432491869866063



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
anatomical space7.80e-0757


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.16.01049
MA0004.10.360508
MA0006.10.604851
MA0007.11.63994
MA0009.10.780842
MA0014.11.092
MA0017.10.233089
MA0019.10.603066
MA0024.10.737933
MA0025.11.01089
MA0027.12.42079
MA0028.10.219287
MA0029.10.716673
MA0030.10.723093
MA0031.10.688336
MA0038.11.24163
MA0040.10.79313
MA0041.10.291712
MA0042.10.279998
MA0043.10.875991
MA0046.10.816137
MA0048.10.066679
MA0050.10.396459
MA0051.10.504875
MA0052.10.801048
MA0055.10.0139872
MA0056.10
MA0057.10.216209
MA0058.10.273976
MA0059.10.28489
MA0060.10.145297
MA0061.10.973999
MA0063.10
MA0066.10.485868
MA0067.11.12095
MA0068.10.22316
MA0069.10.801381
MA0070.10.791856
MA0071.12.71242
MA0072.10.783532
MA0073.12.92131
MA0074.10.451832
MA0076.10.249619
MA0077.10.762273
MA0078.10.536502
MA0081.10.305576
MA0083.10.875209
MA0084.11.44691
MA0087.10.832758
MA0088.10.14959
MA0089.10
MA0090.10.329158
MA0091.10.372635
MA0092.10.877917
MA0093.10.226349
MA0095.10
MA0098.10
MA0100.10.440912
MA0101.10.795627
MA0103.10.242398
MA0105.11.56265
MA0106.10.543967
MA0107.10.66744
MA0108.20.625209
MA0109.10
MA0111.10.342068
MA0113.10.516916
MA0114.10.500166
MA0115.10.878749
MA0116.10.210297
MA0117.10.846964
MA0119.10.293392
MA0122.10.866511
MA0124.11.06819
MA0125.10.994853
MA0130.10
MA0131.10.598671
MA0132.10
MA0133.10
MA0135.10.911905
MA0136.10.470672
MA0139.11.26076
MA0140.10.440804
MA0141.10.719522
MA0142.10.674191
MA0143.10.53259
MA0144.10.506239
MA0145.10.664015
MA0146.11.62155
MA0147.10.179496
MA0148.10.375491
MA0149.10.2978
MA0062.20.649383
MA0035.20.44524
MA0039.21.98211
MA0138.20.590987
MA0002.20.391079
MA0137.20.257017
MA0104.20.134457
MA0047.20.495607
MA0112.20.0422488
MA0065.20.373167
MA0150.10.346631
MA0151.10
MA0152.10.495709
MA0153.10.92832
MA0154.10.232525
MA0155.14.66496
MA0156.10.248865
MA0157.10.642984
MA0158.10
MA0159.10.187774
MA0160.10.378276
MA0161.10
MA0162.11.0367
MA0163.10.679942
MA0164.10.471016
MA0080.20.237846
MA0018.20.480226
MA0099.20.584892
MA0079.22.58709
MA0102.21.49914
MA0258.10.156336
MA0259.10.50935
MA0442.10
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