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Coexpression cluster:C2558: Difference between revisions

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{{Coexpression_clusters
{{Coexpression_clusters|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.082837032480696,0,0,0,0,0,0,0.374537259271891,0.557155511649587,0.309498469216314,0.948516764153638,1.11687914003913,1.01741527365641,0.029478255492678,0.322198489588,0.133050698758413,0.446626472916642,0.693834690245877,0.735592065751224,0.0549060649465745,0.325957509341887,0.361276648761166,0.55765303237392,0.881289875945255,0.848915548980513,0.201586646852783,0.262989231446241,0.400884229061524,0.526780960626813,0.826649447583278,0.653697386688898,0,0.0728975751126705,0.077093984435699,0.684841972419043,1.06043816420884,1.0119288960965,0.0486718136065485,0.408994025090247,0.399837432724053,0.327623194072376,0.942634514309662,0.964893985149995,0.0416178427326497,0,0,0,0.0303823191668334,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0137745948241495,0,0,0.169656560659316,0.149637401226179,0.143807977408699,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.201612826790636,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.735870042306661,0.532395930934396,0.687030192201356,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.756977649436606,0.989470567027675,0.678668569920213,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0627459241303645,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0640322205040047,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.145210702642573,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.191309559403354,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.272614009213675,0,0,0,0,0,0,0,0.0824118928404978,0,0,0,0.0789089986057754,0.0529736480204785,0,0,0,0,0,0,0,0.0408567533019575,0,0,0,0.0877941970266383,0,0,0,0,0,0,0,0,0,0,0,0.0469196373315304,0,0,0,0,0,0,0.0582708382012885,0,0,0,0,0.060122588700003,0,0.157572468746099,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0368115019473605,0,0,0,0,0.123914545149119,0,0,0,0,0,0,0,0,0.128460281304596,0,0,0,0,0,0,0,0,0,0,0,0.115084761086022,0,0,0,0,0.0585993079488215,0,0,0,0,0.0749067107755451,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0804146167727012,0,0,0,0,0.0448042842895513,0,0,0.0775504613844595,0,0.0790620517896127,0,0,0,0,0,0,0,0,0.0800410362214332,0,0,0,0,0,0.0721347217979341,0,0.0460825052702691,0.0222033657448865,0,0,0,0,0.110327525703921,0,0,0,0,0,0,0,0,0.0558168060456155,0.183217912531785,0,0.0269678279474476,0,0,0.060346547517227,0.0317050203334407,0.150522826464445,0.28545854753774,0,0,0,0,0,0,0,0,0,0,0.0970426649908326,0,0.0663535486603203,0.0852696671988736,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0281204388731878,0,0,0.0328953981802498,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0645061522333104,0,0.064320887423737,0.0405144918818814,0,0.0426519280681946,0.0650101077405693,0,0,0,0,0,0,0,0,0.0157467137568215,0,0.125394621167623,0,0,0,0.0661191511914413,0,0.0407972803666135,0.0133515564209632,0,0,0,0,0,0,0,0,0,0.0539174741935774,0,0,0.0679744606813858,0.0659408339033261,0,0,0.0909572035293623,0,0,0,0,0,0.0580284054719272,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0212213629697974,0,0,0,0,0,0,0,0,0,0.0429233806980168,0,0,0,0.0778431765528363,0.157734556569545,0.076549908334415,0,0.244922625166224,0.10938689352187,0,0,0,0,0,0,0.0581752393062885,0,0.0403086390560309,0,0,0,0,0,0,0,0,0,0,0,0,0.114247114056015,0,0,0.0408295247396738,0,0,0.0271819376754428,0.116907281006366,0,0.059996549492054,0,0,0.063914004774844,0.0283076897745917,0.103384095489567,0,0,0,0,0,0,0,0,0,0.142399000819678,0|full_id=C2558_CD14_Monocytederived_Macrophage_spleen_dura_lymph_left|gostat_on_coexpression_clusters=GO:0030886!negative regulation of myeloid dendritic cell activation!0.00373837277758154!3586$GO:0045355!negative regulation of interferon-alpha biosynthetic process!0.00373837277758154!3586$GO:0005141!interleukin-10 receptor binding!0.00373837277758154!3586$GO:0032695!negative regulation of interleukin-12 production!0.00373837277758154!3586$GO:0030885!regulation of myeloid dendritic cell activation!0.00421703056648373!3586$GO:0045347!negative regulation of MHC class II biosynthetic process!0.00421703056648373!3586$GO:0032655!regulation of interleukin-12 production!0.00421703056648373!3586$GO:0007253!cytoplasmic sequestering of NF-kappaB!0.00421703056648373!3586$GO:0001773!myeloid dendritic cell activation!0.00421703056648373!3586$GO:0042347!negative regulation of NF-kappaB import into nucleus!0.00421703056648373!3586$GO:0045348!positive regulation of MHC class II biosynthetic process!0.00421703056648373!3586$GO:0045354!regulation of interferon-alpha biosynthetic process!0.00421703056648373!3586$GO:0032607!interferon-alpha production!0.00421703056648373!3586$GO:0045349!interferon-alpha biosynthetic process!0.00421703056648373!3586$GO:0045342!MHC class II biosynthetic process!0.00421703056648373!3586$GO:0045346!regulation of MHC class II biosynthetic process!0.00421703056648373!3586$GO:0032615!interleukin-12 production!0.00421703056648373!3586$GO:0007267!cell-cell signaling!0.00421703056648373!6507;3586$GO:0001504!neurotransmitter uptake!0.00421703056648373!6507$GO:0032606!interferon type I production!0.00421703056648373!3586$GO:0042130!negative regulation of T cell proliferation!0.00421703056648373!3586$GO:0005313!L-glutamate transmembrane transporter activity!0.00421703056648373!6507$GO:0045351!interferon type I biosynthetic process!0.00421703056648373!3586$GO:0045191!regulation of isotype switching!0.00421703056648373!3586$GO:0015172!acidic amino acid transmembrane transporter activity!0.00421703056648373!6507$GO:0042994!cytoplasmic sequestering of transcription factor!0.00421703056648373!3586$GO:0002237!response to molecule of bacterial origin!0.00421703056648373!3586$GO:0042092!T-helper 2 type immune response!0.00421703056648373!3586$GO:0001818!negative regulation of cytokine production!0.00421703056648373!3586$GO:0051220!cytoplasmic sequestering of protein!0.00421703056648373!3586$GO:0042308!negative regulation of protein import into nucleus!0.00421703056648373!3586$GO:0002208!somatic diversification of immunoglobulins during immune response!0.00421703056648373!3586$GO:0002381!immunoglobulin production during immune response!0.00421703056648373!3586$GO:0042992!negative regulation of transcription factor import into nucleus!0.00421703056648373!3586$GO:0050672!negative regulation of lymphocyte proliferation!0.00421703056648373!3586$GO:0002204!somatic recombination of immunoglobulin genes during immune response!0.00421703056648373!3586$GO:0050868!negative regulation of T cell activation!0.00421703056648373!3586$GO:0045190!isotype switching!0.00421703056648373!3586$GO:0032945!negative regulation of mononuclear cell proliferation!0.00421703056648373!3586$GO:0042345!regulation of NF-kappaB import into nucleus!0.00422524021915686!3586$GO:0042348!NF-kappaB import into nucleus!0.00422524021915686!3586$GO:0046823!negative regulation of nucleocytoplasmic transport!0.00422524021915686!3586$GO:0015813!L-glutamate transport!0.00422524021915686!6507$GO:0016447!somatic recombination of immunoglobulin gene segments!0.00422524021915686!3586$GO:0051224!negative regulation of protein transport!0.00422524021915686!3586$GO:0015800!acidic amino acid transport!0.00422524021915686!6507$GO:0016444!somatic cell DNA recombination!0.00448512294667026!3586$GO:0016445!somatic diversification of immunoglobulins!0.00448512294667026!3586$GO:0002562!somatic diversification of immune receptors via germline recombination within a single locus!0.00448512294667026!3586$GO:0017153!sodium:dicarboxylate symporter activity!0.00448512294667026!6507$GO:0002200!somatic diversification of immune receptors!0.00460005837853158!3586$GO:0042036!negative regulation of cytokine biosynthetic process!0.00460005837853158!3586$GO:0006835!dicarboxylic acid transport!0.00470647192314367!6507$GO:0005310!dicarboxylic acid transmembrane transporter activity!0.00470647192314367!6507$GO:0002377!immunoglobulin production!0.00480527663985466!3586$GO:0042100!B cell proliferation!0.00480527663985466!3586$GO:0051250!negative regulation of lymphocyte activation!0.00498317648473598!3586$GO:0042990!regulation of transcription factor import into nucleus!0.00532086228261171!3586$GO:0042991!transcription factor import into nucleus!0.00532086228261171!3586$GO:0042306!regulation of protein import into nucleus!0.00539139544131378!3586$GO:0033157!regulation of intracellular protein transport!0.00539139544131378!3586$GO:0030595!leukocyte chemotaxis!0.00554546659648675!3586$GO:0032507!maintenance of cellular protein localization!0.0056622003417305!3586$GO:0050864!regulation of B cell activation!0.0056622003417305!3586$GO:0051651!maintenance of cellular localization!0.0056622003417305!3586$GO:0032386!regulation of intracellular transport!0.0056622003417305!3586$GO:0045185!maintenance of protein localization!0.00580071207558523!3586$GO:0002440!production of molecular mediator of immune response!0.00584912688971298!3586$GO:0002274!myeloid leukocyte activation!0.00584912688971298!3586$GO:0051223!regulation of protein transport!0.00597901945045953!3586$GO:0046822!regulation of nucleocytoplasmic transport!0.00602045177069617!3586$GO:0030183!B cell differentiation!0.00602045177069617!3586$GO:0051051!negative regulation of transport!0.00626153430883787!3586$GO:0050900!leukocyte migration!0.00626153430883787!3586$GO:0015179!L-amino acid transmembrane transporter activity!0.00637724512346562!6507$GO:0042129!regulation of T cell proliferation!0.00668647045420683!3586$GO:0005343!organic acid:sodium symporter activity!0.00737562614066439!6507$GO:0015296!anion:cation symporter activity!0.00737797439175931!6507$GO:0042098!T cell proliferation!0.00737797439175931!3586$GO:0001817!regulation of cytokine production!0.00747223366902842!3586$GO:0051235!maintenance of localization!0.00747223366902842!3586$GO:0017148!negative regulation of translation!0.00747223366902842!3586$GO:0050670!regulation of lymphocyte proliferation!0.00747223366902842!3586$GO:0032944!regulation of mononuclear cell proliferation!0.00747223366902842!3586$GO:0031327!negative regulation of cellular biosynthetic process!0.00791142726813731!3586$GO:0009890!negative regulation of biosynthetic process!0.00870251049755147!3586$GO:0016064!immunoglobulin mediated immune response!0.00870251049755147!3586$GO:0019724!B cell mediated immunity!0.00870251049755147!3586$GO:0032943!mononuclear cell proliferation!0.00870251049755147!3586$GO:0045727!positive regulation of translation!0.00870251049755147!3586$GO:0046651!lymphocyte proliferation!0.00870251049755147!3586$GO:0005126!hematopoietin/interferon-class (D200-domain) cytokine receptor binding!0.00943610885175068!3586$GO:0050863!regulation of T cell activation!0.00943610885175068!3586$GO:0042035!regulation of cytokine biosynthetic process!0.00943610885175068!3586$GO:0031328!positive regulation of cellular biosynthetic process!0.00943610885175068!3586$GO:0042113!B cell activation!0.00949330646860266!3586$GO:0015171!amino acid transmembrane transporter activity!0.0097031985626071!6507$GO:0030098!lymphocyte differentiation!0.00975649000092232!3586$GO:0042089!cytokine biosynthetic process!0.0101102086620081!3586$GO:0042107!cytokine metabolic process!0.0101583465632025!3586$GO:0006865!amino acid transport!0.0102517777777559!6507$GO:0009891!positive regulation of biosynthetic process!0.0102517777777559!3586$GO:0002449!lymphocyte mediated immunity!0.0104420024233583!3586$GO:0002250!adaptive immune response!0.0106885360918715!3586$GO:0002460!adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains!0.0106885360918715!3586$GO:0051249!regulation of lymphocyte activation!0.0106885360918715!3586$GO:0006836!neurotransmitter transport!0.0106885360918715!6507$GO:0002443!leukocyte mediated immunity!0.0106885360918715!3586$GO:0001505!regulation of neurotransmitter levels!0.0106885360918715!6507$GO:0050865!regulation of cell activation!0.0108626209758598!3586$GO:0015837!amine transport!0.0113023312774558!6507$GO:0051247!positive regulation of protein metabolic process!0.0113346007808109!3586$GO:0015370!solute:sodium symporter activity!0.0116302848965169!6507$GO:0002521!leukocyte differentiation!0.0117899233592696!3586$GO:0042742!defense response to bacterium!0.0121168876006111!3586$GO:0006606!protein import into nucleus!0.0121168876006111!3586$GO:0046943!carboxylic acid transmembrane transporter activity!0.0121168876006111!6507$GO:0046942!carboxylic acid transport!0.0121168876006111!6507$GO:0051170!nuclear import!0.0121168876006111!3586$GO:0042110!T cell activation!0.0121168876006111!3586$GO:0015849!organic acid transport!0.0121168876006111!6507$GO:0005342!organic acid transmembrane transporter activity!0.0121168876006111!6507$GO:0051248!negative regulation of protein metabolic process!0.0126244345520289!3586$GO:0009617!response to bacterium!0.0127630680133989!3586$GO:0002252!immune effector process!0.0130336914204533!3586$GO:0051049!regulation of transport!0.0130336914204533!3586$GO:0001816!cytokine production!0.0132831418191474!3586$GO:0015294!solute:cation symporter activity!0.0132958028230356!6507$GO:0017038!protein import!0.0141168753275877!3586$GO:0007249!I-kappaB kinase/NF-kappaB cascade!0.0159562573805025!3586$GO:0042330!taxis!0.0162785650400583!3586$GO:0006935!chemotaxis!0.0162785650400583!3586$GO:0006913!nucleocytoplasmic transport!0.0172401688036447!3586$GO:0046649!lymphocyte activation!0.0172401688036447!3586$GO:0051169!nuclear transport!0.0172401688036447!3586$GO:0030097!hemopoiesis!0.0176606066078919!3586$GO:0006916!anti-apoptosis!0.0185092718642826!3586$GO:0048534!hemopoietic or lymphoid organ development!0.0186985862633258!3586$GO:0045321!leukocyte activation!0.0192502490155955!3586$GO:0007626!locomotory behavior!0.0192502490155955!3586$GO:0002520!immune system development!0.0192502490155955!3586$GO:0006417!regulation of translation!0.0193241649736255!3586$GO:0006310!DNA recombination!0.0205408360571791!3586$GO:0031326!regulation of cellular biosynthetic process!0.0206046712896671!3586$GO:0051707!response to other organism!0.0211801702295847!3586$GO:0001775!cell activation!0.0211953183833238!3586$GO:0008509!anion transmembrane transporter activity!0.0211953183833238!6507$GO:0032501!multicellular organismal process!0.021662995930589!6507;3586$GO:0009889!regulation of biosynthetic process!0.021662995930589!3586$GO:0006605!protein targeting!0.021662995930589!3586$GO:0008285!negative regulation of cell proliferation!0.0222082308787569!3586$GO:0043066!negative regulation of apoptosis!0.0222575744863357!3586$GO:0043069!negative regulation of programmed cell death!0.0224033379698629!3586$GO:0016477!cell migration!0.0225471826960967!3586$GO:0006810!transport!0.023112770376829!6507;3586$GO:0015293!symporter activity!0.0231147989916142!6507$GO:0051234!establishment of localization!0.023855702942669!6507;3586$GO:0008083!growth factor activity!0.023855702942669!3586$GO:0051239!regulation of multicellular organismal process!0.0259452236696486!3586$GO:0009607!response to biotic stimulus!0.0267462490658675!3586$GO:0007268!synaptic transmission!0.0267462490658675!6507$GO:0006954!inflammatory response!0.0267462490658675!3586$GO:0007610!behavior!0.0268550136245768!3586$GO:0051179!localization!0.0269409793953437!6507;3586$GO:0005125!cytokine activity!0.0279666644296476!3586$GO:0019226!transmission of nerve impulse!0.0295828715497254!6507$GO:0051704!multi-organism process!0.029671736813535!3586$GO:0015291!secondary active transmembrane transporter activity!0.0318738815999311!6507$GO:0031325!positive regulation of cellular metabolic process!0.0321229753329957!3586$GO:0007243!protein kinase cascade!0.0328910569679788!3586$GO:0031324!negative regulation of cellular metabolic process!0.0329189960355018!3586$GO:0006928!cell motility!0.0329189960355018!3586$GO:0051674!localization of cell!0.0329189960355018!3586$GO:0009893!positive regulation of metabolic process!0.0334095011152632!3586$GO:0051246!regulation of protein metabolic process!0.0357161306587689!3586$GO:0009611!response to wounding!0.0357161306587689!3586$GO:0009892!negative regulation of metabolic process!0.0365987540911655!3586$GO:0007154!cell communication!0.0382169243973137!6507;3586$GO:0042127!regulation of cell proliferation!0.0389099379666876!3586$GO:0005615!extracellular space!0.0433642124796889!3586$GO:0006886!intracellular protein transport!0.0433642124796889!3586$GO:0050789!regulation of biological process!0.0455825782743777!6507;3586$GO:0042981!regulation of apoptosis!0.0461863797398652!3586$GO:0043067!regulation of programmed cell death!0.0464147630813704!3586$GO:0006952!defense response!0.0467994791501073!3586$GO:0042221!response to chemical 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|full_id=C2558_CD14_Monocytederived_Macrophage_spleen_dura_lymph_left
|id=C2558
}}

Latest revision as of 12:08, 17 September 2013


Full id: C2558_CD14_Monocytederived_Macrophage_spleen_dura_lymph_left



Phase1 CAGE Peaks

Hg19::chr1:206944507..206944524,-p3@IL10
Hg19::chr3:9142472..9142491,+p@chr3:9142472..9142491
+
Hg19::chr5:36680430..36680455,+p6@SLC1A3
Hg19::chrX:5644225..5644242,-p1@ENST00000422914


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0030886negative regulation of myeloid dendritic cell activation0.00373837277758154
GO:0045355negative regulation of interferon-alpha biosynthetic process0.00373837277758154
GO:0005141interleukin-10 receptor binding0.00373837277758154
GO:0032695negative regulation of interleukin-12 production0.00373837277758154
GO:0030885regulation of myeloid dendritic cell activation0.00421703056648373
GO:0045347negative regulation of MHC class II biosynthetic process0.00421703056648373
GO:0032655regulation of interleukin-12 production0.00421703056648373
GO:0007253cytoplasmic sequestering of NF-kappaB0.00421703056648373
GO:0001773myeloid dendritic cell activation0.00421703056648373
GO:0042347negative regulation of NF-kappaB import into nucleus0.00421703056648373
GO:0045348positive regulation of MHC class II biosynthetic process0.00421703056648373
GO:0045354regulation of interferon-alpha biosynthetic process0.00421703056648373
GO:0032607interferon-alpha production0.00421703056648373
GO:0045349interferon-alpha biosynthetic process0.00421703056648373
GO:0045342MHC class II biosynthetic process0.00421703056648373
GO:0045346regulation of MHC class II biosynthetic process0.00421703056648373
GO:0032615interleukin-12 production0.00421703056648373
GO:0007267cell-cell signaling0.00421703056648373
GO:0001504neurotransmitter uptake0.00421703056648373
GO:0032606interferon type I production0.00421703056648373
GO:0042130negative regulation of T cell proliferation0.00421703056648373
GO:0005313L-glutamate transmembrane transporter activity0.00421703056648373
GO:0045351interferon type I biosynthetic process0.00421703056648373
GO:0045191regulation of isotype switching0.00421703056648373
GO:0015172acidic amino acid transmembrane transporter activity0.00421703056648373
GO:0042994cytoplasmic sequestering of transcription factor0.00421703056648373
GO:0002237response to molecule of bacterial origin0.00421703056648373
GO:0042092T-helper 2 type immune response0.00421703056648373
GO:0001818negative regulation of cytokine production0.00421703056648373
GO:0051220cytoplasmic sequestering of protein0.00421703056648373
GO:0042308negative regulation of protein import into nucleus0.00421703056648373
GO:0002208somatic diversification of immunoglobulins during immune response0.00421703056648373
GO:0002381immunoglobulin production during immune response0.00421703056648373
GO:0042992negative regulation of transcription factor import into nucleus0.00421703056648373
GO:0050672negative regulation of lymphocyte proliferation0.00421703056648373
GO:0002204somatic recombination of immunoglobulin genes during immune response0.00421703056648373
GO:0050868negative regulation of T cell activation0.00421703056648373
GO:0045190isotype switching0.00421703056648373
GO:0032945negative regulation of mononuclear cell proliferation0.00421703056648373
GO:0042345regulation of NF-kappaB import into nucleus0.00422524021915686
GO:0042348NF-kappaB import into nucleus0.00422524021915686
GO:0046823negative regulation of nucleocytoplasmic transport0.00422524021915686
GO:0015813L-glutamate transport0.00422524021915686
GO:0016447somatic recombination of immunoglobulin gene segments0.00422524021915686
GO:0051224negative regulation of protein transport0.00422524021915686
GO:0015800acidic amino acid transport0.00422524021915686
GO:0016444somatic cell DNA recombination0.00448512294667026
GO:0016445somatic diversification of immunoglobulins0.00448512294667026
GO:0002562somatic diversification of immune receptors via germline recombination within a single locus0.00448512294667026
GO:0017153sodium:dicarboxylate symporter activity0.00448512294667026
GO:0002200somatic diversification of immune receptors0.00460005837853158
GO:0042036negative regulation of cytokine biosynthetic process0.00460005837853158
GO:0006835dicarboxylic acid transport0.00470647192314367
GO:0005310dicarboxylic acid transmembrane transporter activity0.00470647192314367
GO:0002377immunoglobulin production0.00480527663985466
GO:0042100B cell proliferation0.00480527663985466
GO:0051250negative regulation of lymphocyte activation0.00498317648473598
GO:0042990regulation of transcription factor import into nucleus0.00532086228261171
GO:0042991transcription factor import into nucleus0.00532086228261171
GO:0042306regulation of protein import into nucleus0.00539139544131378
GO:0033157regulation of intracellular protein transport0.00539139544131378
GO:0030595leukocyte chemotaxis0.00554546659648675
GO:0032507maintenance of cellular protein localization0.0056622003417305
GO:0050864regulation of B cell activation0.0056622003417305
GO:0051651maintenance of cellular localization0.0056622003417305
GO:0032386regulation of intracellular transport0.0056622003417305
GO:0045185maintenance of protein localization0.00580071207558523
GO:0002440production of molecular mediator of immune response0.00584912688971298
GO:0002274myeloid leukocyte activation0.00584912688971298
GO:0051223regulation of protein transport0.00597901945045953
GO:0046822regulation of nucleocytoplasmic transport0.00602045177069617
GO:0030183B cell differentiation0.00602045177069617
GO:0051051negative regulation of transport0.00626153430883787
GO:0050900leukocyte migration0.00626153430883787
GO:0015179L-amino acid transmembrane transporter activity0.00637724512346562
GO:0042129regulation of T cell proliferation0.00668647045420683
GO:0005343organic acid:sodium symporter activity0.00737562614066439
GO:0015296anion:cation symporter activity0.00737797439175931
GO:0042098T cell proliferation0.00737797439175931
GO:0001817regulation of cytokine production0.00747223366902842
GO:0051235maintenance of localization0.00747223366902842
GO:0017148negative regulation of translation0.00747223366902842
GO:0050670regulation of lymphocyte proliferation0.00747223366902842
GO:0032944regulation of mononuclear cell proliferation0.00747223366902842
GO:0031327negative regulation of cellular biosynthetic process0.00791142726813731
GO:0009890negative regulation of biosynthetic process0.00870251049755147
GO:0016064immunoglobulin mediated immune response0.00870251049755147
GO:0019724B cell mediated immunity0.00870251049755147
GO:0032943mononuclear cell proliferation0.00870251049755147
GO:0045727positive regulation of translation0.00870251049755147
GO:0046651lymphocyte proliferation0.00870251049755147
GO:0005126hematopoietin/interferon-class (D200-domain) cytokine receptor binding0.00943610885175068
GO:0050863regulation of T cell activation0.00943610885175068
GO:0042035regulation of cytokine biosynthetic process0.00943610885175068
GO:0031328positive regulation of cellular biosynthetic process0.00943610885175068
GO:0042113B cell activation0.00949330646860266
GO:0015171amino acid transmembrane transporter activity0.0097031985626071
GO:0030098lymphocyte differentiation0.00975649000092232
GO:0042089cytokine biosynthetic process0.0101102086620081
GO:0042107cytokine metabolic process0.0101583465632025
GO:0006865amino acid transport0.0102517777777559
GO:0009891positive regulation of biosynthetic process0.0102517777777559
GO:0002449lymphocyte mediated immunity0.0104420024233583
GO:0002250adaptive immune response0.0106885360918715
GO:0002460adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains0.0106885360918715
GO:0051249regulation of lymphocyte activation0.0106885360918715
GO:0006836neurotransmitter transport0.0106885360918715
GO:0002443leukocyte mediated immunity0.0106885360918715
GO:0001505regulation of neurotransmitter levels0.0106885360918715
GO:0050865regulation of cell activation0.0108626209758598
GO:0015837amine transport0.0113023312774558
GO:0051247positive regulation of protein metabolic process0.0113346007808109
GO:0015370solute:sodium symporter activity0.0116302848965169
GO:0002521leukocyte differentiation0.0117899233592696
GO:0042742defense response to bacterium0.0121168876006111
GO:0006606protein import into nucleus0.0121168876006111
GO:0046943carboxylic acid transmembrane transporter activity0.0121168876006111
GO:0046942carboxylic acid transport0.0121168876006111
GO:0051170nuclear import0.0121168876006111
GO:0042110T cell activation0.0121168876006111
GO:0015849organic acid transport0.0121168876006111
GO:0005342organic acid transmembrane transporter activity0.0121168876006111
GO:0051248negative regulation of protein metabolic process0.0126244345520289
GO:0009617response to bacterium0.0127630680133989
GO:0002252immune effector process0.0130336914204533
GO:0051049regulation of transport0.0130336914204533
GO:0001816cytokine production0.0132831418191474
GO:0015294solute:cation symporter activity0.0132958028230356
GO:0017038protein import0.0141168753275877
GO:0007249I-kappaB kinase/NF-kappaB cascade0.0159562573805025
GO:0042330taxis0.0162785650400583
GO:0006935chemotaxis0.0162785650400583
GO:0006913nucleocytoplasmic transport0.0172401688036447
GO:0046649lymphocyte activation0.0172401688036447
GO:0051169nuclear transport0.0172401688036447
GO:0030097hemopoiesis0.0176606066078919
GO:0006916anti-apoptosis0.0185092718642826
GO:0048534hemopoietic or lymphoid organ development0.0186985862633258
GO:0045321leukocyte activation0.0192502490155955
GO:0007626locomotory behavior0.0192502490155955
GO:0002520immune system development0.0192502490155955
GO:0006417regulation of translation0.0193241649736255
GO:0006310DNA recombination0.0205408360571791
GO:0031326regulation of cellular biosynthetic process0.0206046712896671
GO:0051707response to other organism0.0211801702295847
GO:0001775cell activation0.0211953183833238
GO:0008509anion transmembrane transporter activity0.0211953183833238
GO:0032501multicellular organismal process0.021662995930589
GO:0009889regulation of biosynthetic process0.021662995930589
GO:0006605protein targeting0.021662995930589
GO:0008285negative regulation of cell proliferation0.0222082308787569
GO:0043066negative regulation of apoptosis0.0222575744863357
GO:0043069negative regulation of programmed cell death0.0224033379698629
GO:0016477cell migration0.0225471826960967
GO:0006810transport0.023112770376829
GO:0015293symporter activity0.0231147989916142
GO:0051234establishment of localization0.023855702942669
GO:0008083growth factor activity0.023855702942669
GO:0051239regulation of multicellular organismal process0.0259452236696486
GO:0009607response to biotic stimulus0.0267462490658675
GO:0007268synaptic transmission0.0267462490658675
GO:0006954inflammatory response0.0267462490658675
GO:0007610behavior0.0268550136245768
GO:0051179localization0.0269409793953437
GO:0005125cytokine activity0.0279666644296476
GO:0019226transmission of nerve impulse0.0295828715497254
GO:0051704multi-organism process0.029671736813535
GO:0015291secondary active transmembrane transporter activity0.0318738815999311
GO:0031325positive regulation of cellular metabolic process0.0321229753329957
GO:0007243protein kinase cascade0.0328910569679788
GO:0031324negative regulation of cellular metabolic process0.0329189960355018
GO:0006928cell motility0.0329189960355018
GO:0051674localization of cell0.0329189960355018
GO:0009893positive regulation of metabolic process0.0334095011152632
GO:0051246regulation of protein metabolic process0.0357161306587689
GO:0009611response to wounding0.0357161306587689
GO:0009892negative regulation of metabolic process0.0365987540911655
GO:0007154cell communication0.0382169243973137
GO:0042127regulation of cell proliferation0.0389099379666876
GO:0005615extracellular space0.0433642124796889
GO:0006886intracellular protein transport0.0433642124796889
GO:0050789regulation of biological process0.0455825782743777
GO:0042981regulation of apoptosis0.0461863797398652
GO:0043067regulation of programmed cell death0.0464147630813704
GO:0006952defense response0.0467994791501073
GO:0042221response to chemical stimulus0.0469429105331343



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
monopoietic cell6.14e-5659
monocyte6.14e-5659
monoblast6.14e-5659
promonocyte6.14e-5659
macrophage dendritic cell progenitor1.28e-5361
defensive cell1.34e-5348
phagocyte1.34e-5348
myeloid lineage restricted progenitor cell1.94e-4866
granulocyte monocyte progenitor cell1.70e-4767
myeloid leukocyte2.68e-4572
classical monocyte3.82e-4342
CD14-positive, CD16-negative classical monocyte3.82e-4342
myeloid cell1.94e-26108
common myeloid progenitor1.94e-26108
stuff accumulating cell1.50e-2387
nongranular leukocyte9.13e-23115
hematopoietic lineage restricted progenitor cell3.92e-20120
leukocyte5.53e-19136
hematopoietic oligopotent progenitor cell4.41e-13161
hematopoietic multipotent progenitor cell4.41e-13161
hematopoietic stem cell1.05e-12168
angioblastic mesenchymal cell1.05e-12168
macrophage3.30e-126
hematopoietic cell2.20e-11177
adult endothelial progenitor cell3.42e-073
Uber Anatomy
Ontology termp-valuen
bone marrow4.04e-4076
immune system4.59e-4093
bone element4.17e-3682
hematopoietic system1.64e-3598
blood island1.64e-3598
hemolymphoid system1.09e-33108
skeletal element1.35e-3190
adult organism1.85e-29114
skeletal system2.26e-28100
organ4.00e-16503
lateral plate mesoderm3.20e-14203
neural tube1.13e-1256
neural rod1.13e-1256
future spinal cord1.13e-1256
neural keel1.13e-1256
musculoskeletal system4.28e-12167
telencephalon3.48e-1134
germ layer5.55e-11560
germ layer / neural crest5.55e-11560
embryonic tissue5.55e-11560
presumptive structure5.55e-11560
germ layer / neural crest derived structure5.55e-11560
epiblast (generic)5.55e-11560
anatomical system8.00e-11624
anatomical group9.25e-11625
embryonic structure1.03e-10564
developing anatomical structure1.29e-10581
regional part of nervous system3.88e-1053
regional part of brain3.88e-1053
embryo6.52e-10592
brain grey matter1.18e-0934
gray matter1.18e-0934
regional part of forebrain1.36e-0941
forebrain1.36e-0941
anterior neural tube1.36e-0941
future forebrain1.36e-0941
multi-cellular organism1.65e-09656
cerebral hemisphere2.44e-0932
regional part of telencephalon2.67e-0932
central nervous system5.99e-0981
regional part of cerebral cortex2.12e-0822
neural plate5.05e-0882
presumptive neural plate5.05e-0882
neocortex6.61e-0820
nervous system2.22e-0789
neurectoderm2.40e-0786
brain2.61e-0768
future brain2.61e-0768
mesoderm3.06e-07315
mesoderm-derived structure3.06e-07315
presumptive mesoderm3.06e-07315
cerebral cortex4.21e-0725
pallium4.21e-0725


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.0938548
MA0004.10.71247
MA0006.10.532262
MA0007.12.78189
MA0009.11.20602
MA0014.10.244769
MA0017.10.577281
MA0019.10.873355
MA0024.11.09684
MA0025.11.34373
MA0027.12.83281
MA0028.10.550763
MA0029.11.11704
MA0030.11.10506
MA0031.11.03735
MA0038.10.824639
MA0040.11.12314
MA0041.10.732902
MA0042.10.697662
MA0043.11.20635
MA0046.11.19471
MA0048.10.25531
MA0050.10.69864
MA0051.10.820063
MA0052.11.12718
MA0055.10.396851
MA0056.10
MA0057.10.248209
MA0058.10.605914
MA0059.10.604454
MA0060.10.393285
MA0061.10.360128
MA0063.10
MA0066.10.825101
MA0067.11.53181
MA0068.10.313194
MA0069.11.19071
MA0070.11.17908
MA0071.10.782546
MA0072.11.1744
MA0073.10.100363
MA0074.10.819248
MA0076.10.623864
MA0077.11.16637
MA0078.10.926725
MA0081.10.604638
MA0083.11.21381
MA0084.11.72172
MA0087.11.17185
MA0088.10.182167
MA0089.10
MA0090.10.640115
MA0091.10.715356
MA0092.10.673508
MA0093.10.535768
MA0095.10
MA0098.10
MA0100.10.83965
MA0101.10.539569
MA0103.10.521546
MA0105.10.232357
MA0106.10.869173
MA0107.10.453492
MA0108.21.03412
MA0109.10
MA0111.10.655276
MA0113.12.05499
MA0114.10.447443
MA0115.11.45393
MA0116.10.457606
MA0117.11.24497
MA0119.10.586221
MA0122.11.27173
MA0124.11.41151
MA0125.11.32534
MA0130.10
MA0131.10.94608
MA0132.10
MA0133.10
MA0135.11.23748
MA0136.10.832277
MA0139.10.344952
MA0140.10.779643
MA0141.10.602484
MA0142.11.00381
MA0143.10.887001
MA0144.10.430413
MA0145.10.195821
MA0146.10.061409
MA0147.10.46175
MA0148.10.739888
MA0149.10.769072
MA0062.20.353589
MA0035.20.778873
MA0039.20.10559
MA0138.20.928035
MA0002.20.379056
MA0137.20.558189
MA0104.20.392359
MA0047.20.856092
MA0112.20.551048
MA0065.20.199162
MA0150.10.633493
MA0151.10
MA0152.10.78681
MA0153.11.30799
MA0154.10.229241
MA0155.10.180766
MA0156.10.560797
MA0157.10.97481
MA0158.10
MA0159.10.462502
MA0160.10.756582
MA0161.10
MA0162.10.0928415
MA0163.10.0725493
MA0164.10.90014
MA0080.20.535868
MA0018.20.870662
MA0099.20.7872
MA0079.20.0270533
MA0102.21.75932
MA0258.10.418966
MA0259.10.471671
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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