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{{Coexpression_clusters
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6,0.42392,0.425912,0.380826,0.259046,0.00922992,0.000647553,0.483953,0.347171,0.321735,0.15463,0.13907,0.470121,0.269432,0.250466,0.409882,0.115686,0.408975,0.162633,0.342661,0.27567,0.248127,0.0628839,0.384731,0.319112,0.526476|tfbs_overrepresentation_for_novel_motifs=0.508327,0.0561813,1.25018,0.654974,0.454983,0.653236,0.733342,0.324142,0.321368,0.345702,1.50573,1.83296,0.274093,0.721271,0.453496,0.478935,0.963929,0.395009,0.287891,0.501863,0.500405,0.121147,0.645033,0.44943,0.549618,1.88178,0.25115,1.55072,0.458349,0.659743,0.598009,1.00172,0.359091,0.27659,0.417272,1.1597,0.413782,0.654459,0.388123,0.815792,0.415749,1.42042,0.414516,0.451846,0.824538,1.32072,0.734485,0.609718,0.393318,0.458489,0.817229,0.746838,0.191745,1.08035,1.2359,0.724351,0.4631,0.689906,0.233662,0.688844,1.04369,0.736968,0.321912,0.935408,0.755773,0.899893,1.32544,1.69665,0.991065,1.53343,1.39076,0.330474,1.66643,1.23387,0.269111,2.02182,0.240727,0.917983,0.987729,0.543014,0.293154,0.934302,0.755403,0.327263,1.18161,3.82149,14.0186,0.647361,0.844289,1.79645,1.41984,1.15413,1.01895,0.367039,2.9911,0.381528,1.42387,1.06255,0.849074,5.13318,0.389604,1.01316,1.05685,0.967698,0.88799,0.616433,0.951411,0.717647,0.549347,3.9562,0.512457,1.05402,0.494368,2.58839,1.37132,0.412056,4.84376,1.45429,0.897476,0.968277,1.22546,0.841768,0.650322,0.767198,1.48307,0.918767,0.72668,1.02407,1.2687,2.65061,1.15483,0.601055,1.28328,0.763715,1.43285,2.59164,0.591636,0.643339,1.38998,2.25246,1.84906,1.35224,0.728494,1.05895,0.889806,0.680988,0.87256,2.09294,0.577088,1.69829,0.526389,1.87689,1.15522,0.312599,1.74559,1.56426,0.827475,0.439798,0.54968,0.518696,1.35101,1.13636,0.98692,0.522159,0.906429,0.754576,0.923751,0.731946,0.0938701|tfbs_overrepresentation_jaspar=MA0003.1;4.3611,MA0004.1;0.626788,MA0006.1;2.00428,MA0007.1;0.606704,MA0009.1;1.11255,MA0014.1;2.48957,MA0017.1;0.496101,MA0019.1;0.784036,MA0024.1;1.00439,MA0025.1;1.24931,MA0027.1;2.73598,MA0028.1;0.470679,MA0029.1;1.02437,MA0030.1;1.01252,MA0031.1;0.945567,MA0038.1;0.736268,MA0040.1;1.03042,MA0041.1;2.63789,MA0042.1;2.52778,MA0043.1;1.11288,MA0046.1;1.10134,MA0048.1;0.569896,MA0050.1;0.613347,MA0051.1;0.731787,MA0052.1;1.03442,MA0055.1;5.68117,MA0056.1;0,MA0057.1;0.189508,MA0058.1;0.523638,MA0059.1;0.522232,MA0060.1;0.321781,MA0061.1;0.291022,MA0063.1;0,MA0066.1;0.736721,MA0067.1;1.43651,MA0068.1;0.247962,MA0069.1;1.09737,MA0070.1;1.08584,MA0071.1;0.695094,MA0072.1;1.0812,MA0073.1;3.39561,MA0074.1;0.730989,MA0076.1;0.540943,MA0077.1;1.07324,MA0078.1;0.836493,MA0081.1;0.522409,MA0083.1;1.12028,MA0084.1;1.62584,MA0087.1;1.07867,MA0088.1;0.132006,MA0089.1;0,MA0090.1;0.556637,MA0091.1;0.629594,MA0092.1;0.588959,MA0093.1;0.456342,MA0095.1;0,MA0098.1;0,MA0100.1;0.750974,MA0101.1;0.459973,MA0103.1;0.442769,MA0105.1;0.175503,MA0106.1;0.779931,MA0107.1;0.378225,MA0108.2;0.94238,MA0109.1;0,MA0111.1;1.40074,MA0113.1;0.797251,MA0114.1;0.372523,MA0115.1;1.35895,MA0116.1;0.382106,MA0117.1;1.1512,MA0119.1;0.504689,MA0122.1;1.17777,MA0124.1;1.31673,MA0125.1;1.23103,MA0130.1;0,MA0131.1;0.855546,MA0132.1;0,MA0133.1;0,MA0135.1;1.14377,MA0136.1;0.743749,MA0139.1;0.277033,MA0140.1;0.692258,MA0141.1;0.520334,MA0142.1;0.912455,MA0143.1;0.797437,MA0144.1;0.356507,MA0145.1;2.70679,MA0146.1;0.6031,MA0147.1;1.00307,MA0148.1;0.653474,MA0149.1;0.681935,MA0062.2;0.284987,MA0035.2;0.691506,MA0039.2;0.801354,MA0138.2;0.837782,MA0002.2;0.30855,MA0137.2;0.47779,MA0104.2;0.320919,MA0047.2;0.767096,MA0112.2;0.425004,MA0065.2;0.449243,MA0150.1;0.550239,MA0151.1;0,MA0152.1;0.69926,MA0153.1;1.21379,MA0154.1;1.57192,MA0155.1;0.130813,MA0156.1;1.20729,MA0157.1;0.883854,MA0158.1;0,MA0159.1;0.386729,MA0160.1;0.669748,MA0161.1;0,MA0162.1;0.21472,MA0163.1;0.382496,MA0164.1;0.810347,MA0080.2;0.456437,MA0018.2;0.781393,MA0099.2;0.699641,MA0079.2;0.823998,MA0102.2;1.66336,MA0258.1;0.345771,MA0259.1;1.80881,MA0442.1;0}}
|full_id=C1935_heart_pineal_mature_neuroblastoma_putamen_neuroectodermal_occipital
|id=C1935
|ontology_enrichment_celltype=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0007023!1.30e-31!115;UBERON:0000073!2.37e-30!94;UBERON:0001016!2.37e-30!94;UBERON:0005743!3.73e-30!86;UBERON:0001017!3.85e-29!82;UBERON:0000955!1.98e-26!69;UBERON:0006238!1.98e-26!69;UBERON:0001049!1.01e-24!57;UBERON:0005068!1.01e-24!57;UBERON:0006241!1.01e-24!57;UBERON:0007135!1.01e-24!57;UBERON:0002346!1.92e-24!90;UBERON:0000924!4.68e-24!173;UBERON:0006601!4.68e-24!173;UBERON:0002616!2.05e-23!59;UBERON:0003075!2.17e-23!86;UBERON:0007284!2.17e-23!86;UBERON:0004121!5.53e-23!169;UBERON:0000153!1.95e-21!129;UBERON:0007811!1.95e-21!129;UBERON:0000033!2.31e-21!123;UBERON:0003080!5.15e-20!42;UBERON:0002780!1.78e-19!41;UBERON:0001890!1.78e-19!41;UBERON:0006240!1.78e-19!41;UBERON:0003056!1.06e-17!61;UBERON:0000475!3.93e-17!365;UBERON:0000481!2.85e-16!347;UBERON:0001893!8.45e-16!34;UBERON:0002020!8.88e-16!34;UBERON:0003528!8.88e-16!34;UBERON:0001869!1.13e-15!32;UBERON:0002791!2.53e-15!33;UBERON:0000468!6.67e-15!659;UBERON:0000062!9.11e-13!511;UBERON:0000956!1.93e-12!25;UBERON:0000203!1.93e-12!25;UBERON:0002619!4.76e-12!22;UBERON:0001950!3.53e-11!20;UBERON:0000064!1.77e-10!219;UBERON:0000467!1.92e-09!625;UBERON:0000480!3.12e-09!626;UBERON:0000922!4.70e-09!612;UBERON:0000477!4.81e-09!286;UBERON:0002050!7.96e-08!605;UBERON:0005423!7.96e-08!605;UBERON:0000923!1.45e-07!604;UBERON:0005291!1.45e-07!604;UBERON:0006598!1.45e-07!604;UBERON:0002532!1.45e-07!604
}}

Latest revision as of 11:55, 17 September 2013


Full id: C1935_heart_pineal_mature_neuroblastoma_putamen_neuroectodermal_occipital



Phase1 CAGE Peaks

Hg19::chr4:142053952..142053977,-p2@RNF150
Hg19::chr4:142054469..142054497,-p4@RNF150
Hg19::chr4:142054498..142054547,-p3@RNF150
Hg19::chr4:142054563..142054577,-p6@RNF150
Hg19::chr4:142054590..142054648,-p1@RNF150


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
adult organism3.02e-37114
central nervous system2.55e-3181
nervous system2.68e-3089
brain2.10e-2968
future brain2.10e-2968
neural tube1.43e-2656
neural rod1.43e-2656
future spinal cord1.43e-2656
neural keel1.43e-2656
organ system subdivision2.60e-26223
regional part of nervous system1.68e-2553
regional part of brain1.68e-2553
neurectoderm5.20e-2586
neural plate3.07e-2482
presumptive neural plate3.07e-2482
ectoderm-derived structure5.47e-24171
ectoderm5.47e-24171
presumptive ectoderm5.47e-24171
regional part of forebrain2.51e-2241
forebrain2.51e-2241
anterior neural tube2.51e-2241
future forebrain2.51e-2241
structure with developmental contribution from neural crest5.75e-21132
pre-chordal neural plate7.55e-1861
telencephalon8.06e-1834
brain grey matter9.78e-1834
gray matter9.78e-1834
cerebral hemisphere1.22e-1732
ecto-epithelium3.32e-17104
regional part of telencephalon5.68e-1732
anatomical cluster5.63e-16373
multi-tissue structure3.06e-15342
cerebral cortex1.08e-1325
pallium1.08e-1325
regional part of cerebral cortex4.74e-1322
multi-cellular organism2.67e-12656
neocortex4.90e-1220
organ9.77e-12503
anatomical system3.60e-09624
anatomical group4.95e-09625
organ part1.02e-08218
embryo6.56e-08592
developing anatomical structure2.57e-07581
germ layer5.52e-07560
germ layer / neural crest5.52e-07560
embryonic tissue5.52e-07560
presumptive structure5.52e-07560
germ layer / neural crest derived structure5.52e-07560
epiblast (generic)5.52e-07560
embryonic structure7.50e-07564


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.14.3611
MA0004.10.626788
MA0006.12.00428
MA0007.10.606704
MA0009.11.11255
MA0014.12.48957
MA0017.10.496101
MA0019.10.784036
MA0024.11.00439
MA0025.11.24931
MA0027.12.73598
MA0028.10.470679
MA0029.11.02437
MA0030.11.01252
MA0031.10.945567
MA0038.10.736268
MA0040.11.03042
MA0041.12.63789
MA0042.12.52778
MA0043.11.11288
MA0046.11.10134
MA0048.10.569896
MA0050.10.613347
MA0051.10.731787
MA0052.11.03442
MA0055.15.68117
MA0056.10
MA0057.10.189508
MA0058.10.523638
MA0059.10.522232
MA0060.10.321781
MA0061.10.291022
MA0063.10
MA0066.10.736721
MA0067.11.43651
MA0068.10.247962
MA0069.11.09737
MA0070.11.08584
MA0071.10.695094
MA0072.11.0812
MA0073.13.39561
MA0074.10.730989
MA0076.10.540943
MA0077.11.07324
MA0078.10.836493
MA0081.10.522409
MA0083.11.12028
MA0084.11.62584
MA0087.11.07867
MA0088.10.132006
MA0089.10
MA0090.10.556637
MA0091.10.629594
MA0092.10.588959
MA0093.10.456342
MA0095.10
MA0098.10
MA0100.10.750974
MA0101.10.459973
MA0103.10.442769
MA0105.10.175503
MA0106.10.779931
MA0107.10.378225
MA0108.20.94238
MA0109.10
MA0111.11.40074
MA0113.10.797251
MA0114.10.372523
MA0115.11.35895
MA0116.10.382106
MA0117.11.1512
MA0119.10.504689
MA0122.11.17777
MA0124.11.31673
MA0125.11.23103
MA0130.10
MA0131.10.855546
MA0132.10
MA0133.10
MA0135.11.14377
MA0136.10.743749
MA0139.10.277033
MA0140.10.692258
MA0141.10.520334
MA0142.10.912455
MA0143.10.797437
MA0144.10.356507
MA0145.12.70679
MA0146.10.6031
MA0147.11.00307
MA0148.10.653474
MA0149.10.681935
MA0062.20.284987
MA0035.20.691506
MA0039.20.801354
MA0138.20.837782
MA0002.20.30855
MA0137.20.47779
MA0104.20.320919
MA0047.20.767096
MA0112.20.425004
MA0065.20.449243
MA0150.10.550239
MA0151.10
MA0152.10.69926
MA0153.11.21379
MA0154.11.57192
MA0155.10.130813
MA0156.11.20729
MA0157.10.883854
MA0158.10
MA0159.10.386729
MA0160.10.669748
MA0161.10
MA0162.10.21472
MA0163.10.382496
MA0164.10.810347
MA0080.20.456437
MA0018.20.781393
MA0099.20.699641
MA0079.20.823998
MA0102.21.66336
MA0258.10.345771
MA0259.11.80881
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
CTCF#1066444.288205098460020.005152015588243280.0239430141067298
EBF1#187947.12517347725520.0007230531046774210.00577331370026033
EP300#203345.419153380978560.00209386927943890.012124729079359
GATA2#2624410.19594538684320.0001775447777609820.00215787257588493
MAX#414945.16204440720570.002526309009485180.0140030350621814
MYC#460944.177825497287520.005691969036823440.0256898683766985
RAD21#588548.284027116365060.0004011622639122450.00386860440265291
REST#597847.720022972902420.0005286363773650570.00457455088372104
SMC3#9126412.03594627594639.2360978468394e-050.00134384065620794
SPI1#668846.563458806818180.0009957429636454020.00714345372854528
TAF1#687253.343046285745290.002394600090870310.0135520558627075
TAF7#687949.146455523939130.0002720662872412990.00290356948428306
YY1#752854.911170749853860.00034993140821360.00353072034995847



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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