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{{Coexpression_clusters
{
|coexpression_dpi_cluster_scores_median=0,0,

Latest revision as of 11:26, 17 September 2013


Full id: C585_Mallassezderived_amniotic_Small_chorionic_nasal_Keratinocyte_Sebocyte



Phase1 CAGE Peaks

Hg19::chr11:123079774..123079777,+p@chr11:123079774..123079777
+
Hg19::chr11:18154245..18154256,+p1@MRGPRX3
Hg19::chr11:93754316..93754353,+p2@HEPHL1
Hg19::chr12:28299014..28299023,+p20@CCDC91
Hg19::chr17:18353495..18353501,+p1@KRT16P4
Hg19::chr1:14465017..14465026,+p@chr1:14465017..14465026
+
Hg19::chr1:7447129..7447134,+p@chr1:7447129..7447134
+
Hg19::chr21:27558561..27558565,-p@chr21:27558561..27558565
-
Hg19::chr22:23586671..23586679,+p@chr22:23586671..23586679
+
Hg19::chr5:167247750..167247771,+p10@ODZ2
Hg19::chr5:167247779..167247789,+p20@ODZ2
Hg19::chr5:167247865..167247872,+p23@ODZ2
Hg19::chr8:7752197..7752201,+p1@DEFB4A
Hg19::chr9:22256680..22256685,+p@chr9:22256680..22256685
+
Hg19::chr9:27524283..27524289,+p3@IFNK


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0005132interferon-alpha/beta receptor binding0.0463834531334388
GO:0045089positive regulation of innate immune response0.0463834531334388
GO:0045088regulation of innate immune response0.0463834531334388



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.16.18825e-05
MA0004.10.711841
MA0006.10.137644
MA0007.10.241375
MA0009.10.669377
MA0014.10.00275422
MA0017.10.16476
MA0019.10.38027
MA0024.10.570967
MA0025.10.796882
MA0027.12.25966
MA0028.10.148561
MA0029.10.588958
MA0030.10.578277
MA0031.10.518602
MA0038.10.34128
MA0040.10.594421
MA0041.10.27117
MA0042.10.245557
MA0043.10.669676
MA0046.10.659066
MA0048.10.0212749
MA0050.10.246257
MA0051.10.337676
MA0052.10.598036
MA0055.10.579321
MA0056.10
MA0057.10.0873069
MA0058.10.182945
MA0059.10.182001
MA0060.10.237888
MA0061.10.0537738
MA0063.10
MA0066.10.341645
MA0067.10.975379
MA0068.10.147451
MA0069.10.655419
MA0070.10.644843
MA0071.10.308534
MA0072.10.640598
MA0073.15.61316e-08
MA0074.10.894848
MA0076.10.194691
MA0077.10.633326
MA0078.10.424186
MA0081.10.536866
MA0083.10.676499
MA0084.11.15904
MA0087.10.63829
MA0088.10.244241
MA0089.10
MA0090.11.12017
MA0091.10.258318
MA0092.10.228476
MA0093.10.851459
MA0095.10
MA0098.10
MA0100.10.353174
MA0101.10.141917
MA0103.10.411001
MA0105.10.0162551
MA0106.10.37688
MA0107.10.650533
MA0108.20.515791
MA0109.10
MA0111.10.215855
MA0113.10.39123
MA0114.10.30732
MA0115.10.900969
MA0116.10.0971018
MA0117.10.705104
MA0119.10.170362
MA0122.10.729811
MA0124.10.860724
MA0125.10.779672
MA0130.10
MA0131.10.440395
MA0132.10
MA0133.10
MA0135.11.66629
MA0136.10.347318
MA0139.10.0481205
MA0140.10.826015
MA0141.10.180729
MA0142.10.489543
MA0143.10.391385
MA0144.10.596391
MA0145.10.7339
MA0146.10.00187713
MA0147.10.0991954
MA0148.10.276339
MA0149.10.298252
MA0062.20.0512998
MA0035.20.305721
MA0039.20.000598337
MA0138.20.425279
MA0002.21.25767
MA0137.20.465392
MA0104.20.0667907
MA0047.20.366327
MA0112.20.124752
MA0065.20.140846
MA0150.10.201098
MA0151.10
MA0152.10.311809
MA0153.10.763487
MA0154.10.187751
MA0155.10.11478
MA0156.10.469333
MA0157.10.46471
MA0158.10
MA0159.10.0995776
MA0160.10.786431
MA0161.10
MA0162.10.000900738
MA0163.10.0365728
MA0164.10.402162
MA0080.20.139746
MA0018.20.378086
MA0099.20.839067
MA0079.28.87017e-09
MA0102.21.1957
MA0258.10.27007
MA0259.10.104286
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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