Coexpression cluster:C22: Difference between revisions
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{{Coexpression_clusters | {{Coexpression_clusters|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.410516934126256,0.404032369974143,0.266978847367061,0,0,0,0,0,0.0751400469735772,0.323868714649035,0.380900342105214,0.437129897190998,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0853579634813876,0,0,0,0,0.0837191039350518,0.0826628337153937,0.0462331160303238,0.0223101390803168,0,0,0,0,0,0,0,0,0,0,0,0,0.330094213592205,0.33735429485416,0.331795568716987,0,0.193266156112807,0,0.710193988249595,0.785980071757905,0.867682311429889,0.0671402540299821,0.55719166837821,0.527273946548287,0.469566853250347,0.125231147636021,0.442108883935998,0.406665726542748,0.419100053108901,0.0990527871236345,0.143070424715714,0.0661163340840885,0.105969788764328,0.0825814495782827,0.573802644356931,0.458303244923176,0.490058324208733,0.0466158536071809,0.717289740222004,0.709569228037195,0.63238196706969,0.120101680109954,0,0,0.114327445550711,0.0523039447392876,0,0.0922914887002101,0,0.809113884054661,0.812854651821977,0.772617229528057,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.092892723212638,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.081825314342242,0.109996748514441,0.139478375171065,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.758058979097941,0.8199594056781,0.7967175357191,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.261755686906388,0.435480222140789,0.21494058611927,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0266094859650764,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0881268324752877,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0261550693490902,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0|full_id=C22_CD4_CD8_Natural_Basophils_CD14_Peripheral_CD19|gostat_on_coexpression_clusters=GO:0043229!intracellular organelle!2.38049931056861e-08!6119;6832;56160;10365;55297;204851;8661;1316;10153;65057;81565;64147;829;5515;54904;10671;60561;10885;51621;51003;3725;90411;26092;2908;7431;2534;84365;55422;8899;92140;7259;26984;84447;26986;4750;259230;51282;5144;10933;25949;10432;57649;3422;57326;10775;1182;83715;79811;80714;10449;5264;57132;9648;58487;4306;10123;27086;8880;4247;51466;29940;9975;114327;118472$GO:0043226!organelle!2.38049931056861e-08!6119;6832;56160;10365;55297;204851;8661;1316;10153;65057;81565;64147;829;5515;54904;10671;60561;10885;51621;51003;3725;90411;26092;2908;7431;2534;84365;55422;8899;92140;7259;26984;84447;26986;4750;259230;51282;5144;10933;25949;10432;57649;3422;57326;10775;1182;83715;79811;80714;10449;5264;57132;9648;58487;4306;10123;27086;8880;4247;51466;29940;9975;114327;118472$GO:0043231!intracellular membrane-bound organelle!2.38049931056861e-08!6119;6832;56160;10365;55297;204851;8661;1316;10153;65057;5515;54904;60561;10885;51621;51003;3725;90411;26092;2908;2534;84365;55422;8899;92140;7259;26984;84447;26986;4750;259230;51282;10933;25949;10432;57649;3422;57326;10775;1182;79811;80714;10449;5264;57132;9648;58487;27086;10123;4306;8880;4247;29940;114327;9975;118472$GO:0043227!membrane-bound organelle!2.38049931056861e-08!6119;6832;56160;10365;55297;204851;8661;1316;10153;65057;5515;54904;60561;10885;51621;51003;3725;90411;26092;2908;2534;84365;55422;8899;92140;7259;26984;84447;26986;4750;259230;51282;10933;25949;10432;57649;3422;57326;10775;1182;79811;80714;10449;5264;57132;9648;58487;27086;10123;4306;8880;4247;29940;114327;9975;118472$GO:0044424!intracellular part!4.33330089415057e-08!6119;56160;10365;10153;64147;10885;90411;26092;2908;7431;27327;7259;4750;51282;5144;10933;57326;10775;1182;83715;57132;58487;27086;55573;8880;9975;10209;118472;55297;6832;8661;204851;65057;1316;829;81565;5515;54904;10671;60561;51621;3725;51003;9908;9354;2534;84365;55422;92140;5295;8899;26984;84447;26986;259230;57649;10432;25949;3422;80714;79811;10449;5264;9648;10123;4306;4247;51466;29940;7852;114327$GO:0016070!RNA metabolic process!4.84664175355703e-08!56160;10365;204851;1316;10153;5515;54904;10885;51621;51003;3725;7110;2908;84365;55422;55253;8899;26986;51282;10933;57649;10432;25949;10775;133746;80714;79811;9836;58487;27086;4306;8880;9975;118472$GO:0044446!intracellular organelle part!1.18579757723832e-06!6119;6832;25949;10432;57649;65057;57326;81565;64147;83715;1182;829;10671;60561;10885;51003;3725;26092;2908;7431;9648;84365;8899;92140;4306;26984;84447;4247;114327;26986;259230;5144$GO:0044422!organelle part!1.18579757723832e-06!6119;6832;25949;10432;57649;65057;57326;81565;64147;83715;1182;829;10671;60561;10885;51003;3725;26092;2908;7431;9648;84365;8899;92140;4306;26984;84447;4247;114327;26986;259230;5144$GO:0005634!nucleus!1.22193353533065e-06!6119;6832;56160;10365;204851;8661;1316;10153;65057;5515;54904;10885;51621;51003;3725;26092;2908;84365;55422;8899;92140;7259;26986;4750;259230;51282;10933;25949;57649;10432;10775;57326;80714;79811;58487;27086;10123;4306;8880;9975;118472$GO:0005622!intracellular!1.72136955155334e-06!6119;56160;10365;10153;64147;10885;90411;26092;2908;7431;27327;7259;4750;51282;5144;64333;10933;57326;10775;1182;83715;57132;58487;27086;55573;8880;9975;10209;118472;55297;6832;8661;204851;65057;1316;829;81565;5515;54941;54904;10671;60561;51621;3725;51003;9354;9908;2534;84365;55422;92140;5295;8899;26984;84447;26986;259230;57649;10432;25949;3422;80714;79811;10449;5264;9648;10123;4306;8738;4247;51466;29940;7852;114327$GO:0006139!nucleobase, nucleoside, nucleotide and nucleic acid metabolic process!4.5361807911798e-06!6119;6832;56160;10365;204851;1316;10153;65057;5515;54904;10885;51621;51003;3725;7110;2908;84365;55422;55253;8899;7259;26986;51282;10933;57649;10432;25949;10775;57326;133746;80714;79811;9836;58487;27086;4306;8880;9975;118472$GO:0031323!regulation of cellular metabolic process!4.5361807911798e-06!56160;10933;10365;10432;57649;204851;8661;1316;10153;57326;5515;54904;133746;79811;80714;51621;51003;3725;7110;2908;55422;58487;4306;27086;8880;26986;9975;51282;10209;118472$GO:0005515!protein binding!4.5361807911798e-06!246175;56160;10365;204851;8661;81565;829;54941;5515;54904;114781;10671;60561;51621;51003;23247;3725;9354;9908;7110;2908;7431;2534;84365;8899;5295;84447;26986;4750;51282;64333;26051;10933;25949;10432;57649;57326;10775;1182;83715;133746;80714;9836;5264;58487;4306;8738;8880;51466;114327;7852;10233$GO:0019222!regulation of metabolic process!4.5361807911798e-06!56160;10933;10365;10432;57649;204851;8661;1316;10153;57326;829;5515;54904;133746;79811;80714;51621;51003;3725;7110;2908;55422;58487;4306;27086;8880;26986;9975;51282;10209;118472$GO:0010467!gene expression!5.08415557532658e-06!56160;10365;204851;8661;1316;10153;5515;54904;10885;51621;51003;3725;7110;2908;84365;55422;55253;8899;26986;51282;10933;57649;10432;25949;10775;57326;133746;80714;79811;9836;58487;27086;4306;8880;9975;10209;118472$GO:0010468!regulation of gene expression!8.34105383112857e-06!56160;10933;10365;10432;57649;204851;8661;1316;10153;57326;5515;54904;133746;79811;80714;51621;51003;3725;7110;2908;55422;58487;4306;27086;8880;9975;51282;10209;118472$GO:0043283!biopolymer metabolic process!9.49703305556073e-06!6119;6832;56160;10365;204851;1316;10153;65057;54941;5515;54904;64224;10885;51621;51003;3725;9354;7110;2908;2534;84365;55422;55253;8899;5295;7259;84447;26986;4750;51282;54986;10933;25949;57649;10432;10775;133746;79811;80714;9836;58487;27086;4306;8880;4247;9975;118472$GO:0019219!regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process!1.47185230496317e-05!56160;10933;10365;10432;57649;204851;1316;10153;57326;5515;54904;133746;79811;80714;51621;51003;3725;7110;2908;55422;58487;27086;4306;8880;26986;9975;51282;118472$GO:0006350!transcription!2.89338681945918e-05!56160;10933;10365;10432;57649;204851;1316;10153;57326;5515;54904;133746;79811;80714;51621;51003;3725;7110;2908;84365;55422;58487;4306;27086;8880;9975;51282;118472$GO:0006351!transcription, DNA-dependent!3.85069121523815e-05!56160;10933;10365;10432;57649;204851;1316;10153;54904;133746;79811;80714;51621;51003;3725;7110;2908;84365;55422;58487;4306;27086;8880;9975;51282;118472$GO:0032774!RNA biosynthetic process!3.85069121523815e-05!56160;10933;10365;10432;57649;204851;1316;10153;54904;133746;79811;80714;51621;51003;3725;7110;2908;84365;55422;58487;4306;27086;8880;9975;51282;118472$GO:0045449!regulation of transcription!3.89451633936155e-05!56160;10933;10365;10432;57649;204851;1316;10153;57326;5515;54904;133746;79811;80714;51621;51003;3725;7110;2908;55422;58487;27086;4306;8880;9975;51282;118472$GO:0050789!regulation of biological process!5.28644558462554e-05!56160;10365;204851;8661;1316;10153;829;5515;54904;60561;51621;51003;3725;9908;7110;2908;2534;55422;26986;51282;10933;57649;10432;57326;133746;79811;80714;8763;58487;27086;4306;8738;8880;5734;7852;9975;10209;118472$GO:0050794!regulation of cellular process!6.07645703717158e-05!56160;10365;204851;8661;1316;10153;829;5515;54904;60561;51621;51003;3725;9908;7110;2908;55422;26986;51282;10933;57649;10432;57326;133746;80714;79811;8763;58487;27086;4306;8738;8880;7852;9975;10209;118472$GO:0006355!regulation of transcription, DNA-dependent!8.33397843019912e-05!56160;10933;10365;10432;57649;204851;1316;10153;54904;133746;79811;80714;51621;51003;3725;7110;2908;55422;58487;27086;4306;8880;9975;51282;118472$GO:0065007!biological regulation!8.33397843019912e-05!56160;10365;204851;8661;1316;10153;829;5515;54904;60561;51621;51003;3725;9908;7110;2908;2534;55422;26986;259230;51282;10933;57649;10432;1182;57326;133746;79811;80714;8763;58487;27086;4306;8738;8880;5734;7852;9975;10209;118472$GO:0016043!cellular component organization and biogenesis!0.000939806489727041!56160;10933;10432;8661;65057;64147;1182;829;10775;5515;54904;10885;80714;9908;2908;7431;84365;7259;26984;51466;7852;259230;10209$GO:0044428!nuclear part!0.00105857407289522!26092;6119;25949;10432;57649;84365;8899;92140;65057;10885;3725;51003;26986$GO:0043170!macromolecule metabolic process!0.00274682983113233!6119;6832;56160;10365;204851;8661;1316;10153;65057;829;54941;5515;54904;64224;10885;51621;51003;3725;9354;7110;2908;2534;84365;55422;55253;8899;5295;7259;84447;26986;4750;51282;54986;10933;25949;10432;57649;10775;133746;79811;80714;9836;57140;58487;27086;4306;8738;8880;4247;51466;9975;10209;118472$GO:0044237!cellular metabolic process!0.00309627480861559!6119;6832;56160;10365;204851;8661;1316;10153;65057;829;54941;5515;54904;64224;10885;51621;51003;3725;9354;7110;90411;2908;2534;84365;55422;55253;8899;5295;7259;84447;26986;4750;259230;51282;54986;10933;25949;10432;57649;3422;57326;10775;133746;79811;80714;10449;9836;57140;58487;27086;4306;8738;8880;4247;51466;9975;10209;118472$GO:0044464!cell part!0.00412853932711923!6119;56160;10365;10153;64147;64224;10885;90411;26092;2908;7431;27327;7259;124936;4750;51282;5144;64333;10933;440026;57326;10775;1182;83715;57132;58487;27086;55573;8880;9975;10209;118472;6832;55297;8661;204851;65057;1316;113791;829;81565;54941;5515;54904;10671;60561;51621;3725;51003;9354;9908;2534;84365;55422;92140;5295;8899;26984;84447;26986;259230;10424;26051;55007;25949;57649;10432;51669;3422;79811;80714;10681;10449;5264;8763;9648;10123;4306;8738;4247;5734;51466;29940;7852;114327$GO:0006366!transcription from RNA polymerase II promoter!0.00436943806518212!2908;10432;10153;8880;133746;51621;80714;3725;7110$GO:0006396!RNA processing!0.00584637465326544!10885;25949;26986;55253;8899;9836;10775;5515$GO:0000228!nuclear chromosome!0.00646726516320833!6119;84365;3725;65057$GO:0033239!negative regulation of amine metabolic process!0.00646726516320833!3725;5515$GO:0045763!negative regulation of amino acid metabolic process!0.00646726516320833!3725;5515$GO:0001933!negative regulation of protein amino acid phosphorylation!0.00646726516320833!3725;5515$GO:0044238!primary metabolic process!0.00716634198538681!6119;6832;56160;10365;204851;8661;1316;10153;65057;829;54941;5515;54904;64224;10885;51621;51003;3725;9354;7110;2908;2534;84365;55422;55253;8899;5295;7259;84447;26986;4750;259230;51282;54986;10933;25949;10432;57649;3422;57326;10775;133746;79811;80714;10449;9836;5264;57140;58487;27086;4306;8738;8880;4247;9975;10209;118472$GO:0016049!cell growth!0.00919660848647982!54904;56160;10933;259230;5515$GO:0005737!cytoplasm!0.00978630992518552!6832;56160;55297;204851;8661;81565;5515;10671;60561;9908;90411;2908;7431;2534;84365;27327;5295;92140;26984;84447;26986;4750;259230;5144;3422;1182;57326;10449;5264;57132;9648;4306;55573;4247;51466;29940;7852;10209$GO:0008361!regulation of cell size!0.00978630992518552!54904;56160;10933;259230;5515$GO:0003707!steroid hormone receptor activity!0.0102750781499155!2908;9975;10424;4306$GO:0032502!developmental process!0.0134382949356823!56160;10933;1316;57326;81565;5515;54904;133746;79811;80714;3725;5264;25914;2908;8763;2534;8738;5734;51466;7852;259230$GO:0065008!regulation of biological quality!0.0139482538859029!54904;56160;10933;26986;7852;259230;4306;1182;829;5515$GO:0006996!organelle organization and biogenesis!0.0151495845376302!2908;10933;7431;10432;65057;7259;64147;1182;829;10775;54904;10885;51466$GO:0030004!cellular monovalent inorganic cation homeostasis!0.0188293926232484!4306;1182$GO:0055067!monovalent inorganic cation homeostasis!0.0188293926232484!4306;1182$GO:0016455!RNA polymerase II transcription mediator activity!0.0210293445334764!10432;51003$GO:0012505!endomembrane system!0.0222344919942081!26092;9648;92140;4306;1182;26984;84447;4247;60561;259230$GO:0019903!protein phosphatase binding!0.0228347197383268!26051;5295$GO:0004879!ligand-dependent nuclear receptor activity!0.0230510638845802!2908;9975;10424;4306$GO:0016072!rRNA metabolic process!0.0274179711205959!10885;84365;10775$GO:0003702!RNA polymerase II transcription factor activity!0.0293637126013609!51621;10432;51003;3725;7110$GO:0017124!SH3 domain binding!0.0293637126013609!51466;83715$GO:0019902!phosphatase binding!0.0342893265491958!26051;5295$GO:0000119!mediator complex!0.0342893265491958!10432;51003$GO:0009892!negative regulation of metabolic process!0.0361207774297424!57649;3725;58487;57326;829;5515$GO:0005496!steroid binding!0.0364892766763437!2908;10424;4306$GO:0044444!cytoplasmic part!0.0364892766763437!6832;55297;8661;3422;57326;81565;1182;5515;60561;10449;5264;57132;90411;2908;2534;9648;5295;92140;4306;26984;84447;4247;29940;259230;5144$GO:0003712!transcription cofactor activity!0.0366098248388845!133746;10432;51282;57326;7110$GO:0016563!transcription activator activity!0.0378988578829624!133746;10365;10432;1316;51282$GO:0006695!cholesterol biosynthetic process!0.0378988578829624!10449;3422$GO:0005795!Golgi stack!0.0378988578829624!4247;259230$GO:0008033!tRNA processing!0.0378988578829624!55253;9836;10775$GO:0003723!RNA binding!0.0378988578829624!6832;10432;84365;27327;10775;8880;79811;26986;9908$GO:0035026!leading edge cell differentiation!0.0378988578829624!3725$GO:0048388!endosomal lumen acidification!0.0378988578829624!1182$GO:0001667!ameboidal cell migration!0.0378988578829624!7852$GO:0047757!chondroitin-glucuronate 5-epimerase activity!0.0378988578829624!29940$GO:0000782!telomere cap complex!0.0378988578829624!65057$GO:0035030!phosphoinositide 3-kinase complex, class IA!0.0378988578829624!5295$GO:0000783!nuclear telomere cap complex!0.0378988578829624!65057$GO:0008455!alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity!0.0378988578829624!4247$GO:0004883!glucocorticoid receptor activity!0.0378988578829624!2908$GO:0048244!phytanoyl-CoA dioxygenase activity!0.0378988578829624!5264$GO:0032027!myosin light chain binding!0.0378988578829624!7852$GO:0000902!cell morphogenesis!0.0415393574255019!54904;56160;10933;7852;259230;5515$GO:0032989!cellular structure morphogenesis!0.0415393574255019!54904;56160;10933;7852;259230;5515|id=C22|ontology_enrichment_celltype=CL:0000791!2.53e-31!18;CL:0000789!2.53e-31!18;CL:0002420!2.53e-31!18;CL:0002419!2.53e-31!18;CL:0000790!2.53e-31!18;CL:0000738!1.09e-27!136;CL:0000624!2.42e-22!6;CL:0000037!5.12e-22!168;CL:0000566!5.12e-22!168;CL:0000084!1.16e-21!25;CL:0000827!1.16e-21!25;CL:0002031!1.48e-21!120;CL:0002087!2.31e-21!115;CL:0000838!1.75e-20!52;CL:0000988!2.02e-20!177;CL:0000542!5.29e-20!53;CL:0000051!5.29e-20!53;CL:0002242!4.27e-19!55;CL:0002032!8.48e-18!161;CL:0000837!8.48e-18!161;CL:0000625!7.48e-15!11;CL:0000623!2.84e-12!3;CL:0000825!2.84e-12!3;CL:0000898!7.57e-12!3;CL:0000767!2.81e-11!3;CL:0000226!3.59e-11!3;CL:0000842!3.59e-11!3;CL:0002393!2.42e-09!9;CL:0002397!2.42e-09!9;CL:0000815!2.22e-08!2;CL:0000792!2.22e-08!2;CL:0002677!2.22e-08!2;CL:0000766!6.71e-07!72|ontology_enrichment_disease=|ontology_enrichment_uberon=UBERON:0002390!1.35e-07!98;UBERON:0003061!1.35e-07!98|pathway_enrichment=3.07051124390401e-07;0.000194363361739124;12;433;IL-2 up reg. targets 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| ||
|full_id=C22_CD4_CD8_Natural_Basophils_CD14_Peripheral_CD19 | |||
|id=C22 | |||
}} |
Latest revision as of 10:09, 17 September 2013
Full id: C22_CD4_CD8_Natural_Basophils_CD14_Peripheral_CD19
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
p.value | FDR | nGenes | nPathway | Name |
---|---|---|---|---|
3.07051124390401e-07 | 0.000194363361739124 | 12 | 433 | IL-2 up reg. targets (Netpath):NetPath_14 |
Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0043229 | intracellular organelle | 2.38049931056861e-08 |
GO:0043226 | organelle | 2.38049931056861e-08 |
GO:0043231 | intracellular membrane-bound organelle | 2.38049931056861e-08 |
GO:0043227 | membrane-bound organelle | 2.38049931056861e-08 |
GO:0044424 | intracellular part | 4.33330089415057e-08 |
GO:0016070 | RNA metabolic process | 4.84664175355703e-08 |
GO:0044446 | intracellular organelle part | 1.18579757723832e-06 |
GO:0044422 | organelle part | 1.18579757723832e-06 |
GO:0005634 | nucleus | 1.22193353533065e-06 |
GO:0005622 | intracellular | 1.72136955155334e-06 |
GO:0006139 | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 4.5361807911798e-06 |
GO:0031323 | regulation of cellular metabolic process | 4.5361807911798e-06 |
GO:0005515 | protein binding | 4.5361807911798e-06 |
GO:0019222 | regulation of metabolic process | 4.5361807911798e-06 |
GO:0010467 | gene expression | 5.08415557532658e-06 |
GO:0010468 | regulation of gene expression | 8.34105383112857e-06 |
GO:0043283 | biopolymer metabolic process | 9.49703305556073e-06 |
GO:0019219 | regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 1.47185230496317e-05 |
GO:0006350 | transcription | 2.89338681945918e-05 |
GO:0006351 | transcription, DNA-dependent | 3.85069121523815e-05 |
GO:0032774 | RNA biosynthetic process | 3.85069121523815e-05 |
GO:0045449 | regulation of transcription | 3.89451633936155e-05 |
GO:0050789 | regulation of biological process | 5.28644558462554e-05 |
GO:0050794 | regulation of cellular process | 6.07645703717158e-05 |
GO:0006355 | regulation of transcription, DNA-dependent | 8.33397843019912e-05 |
GO:0065007 | biological regulation | 8.33397843019912e-05 |
GO:0016043 | cellular component organization and biogenesis | 0.000939806489727041 |
GO:0044428 | nuclear part | 0.00105857407289522 |
GO:0043170 | macromolecule metabolic process | 0.00274682983113233 |
GO:0044237 | cellular metabolic process | 0.00309627480861559 |
GO:0044464 | cell part | 0.00412853932711923 |
GO:0006366 | transcription from RNA polymerase II promoter | 0.00436943806518212 |
GO:0006396 | RNA processing | 0.00584637465326544 |
GO:0000228 | nuclear chromosome | 0.00646726516320833 |
GO:0033239 | negative regulation of amine metabolic process | 0.00646726516320833 |
GO:0045763 | negative regulation of amino acid metabolic process | 0.00646726516320833 |
GO:0001933 | negative regulation of protein amino acid phosphorylation | 0.00646726516320833 |
GO:0044238 | primary metabolic process | 0.00716634198538681 |
GO:0016049 | cell growth | 0.00919660848647982 |
GO:0005737 | cytoplasm | 0.00978630992518552 |
GO:0008361 | regulation of cell size | 0.00978630992518552 |
GO:0003707 | steroid hormone receptor activity | 0.0102750781499155 |
GO:0032502 | developmental process | 0.0134382949356823 |
GO:0065008 | regulation of biological quality | 0.0139482538859029 |
GO:0006996 | organelle organization and biogenesis | 0.0151495845376302 |
GO:0030004 | cellular monovalent inorganic cation homeostasis | 0.0188293926232484 |
GO:0055067 | monovalent inorganic cation homeostasis | 0.0188293926232484 |
GO:0016455 | RNA polymerase II transcription mediator activity | 0.0210293445334764 |
GO:0012505 | endomembrane system | 0.0222344919942081 |
GO:0019903 | protein phosphatase binding | 0.0228347197383268 |
GO:0004879 | ligand-dependent nuclear receptor activity | 0.0230510638845802 |
GO:0016072 | rRNA metabolic process | 0.0274179711205959 |
GO:0003702 | RNA polymerase II transcription factor activity | 0.0293637126013609 |
GO:0017124 | SH3 domain binding | 0.0293637126013609 |
GO:0019902 | phosphatase binding | 0.0342893265491958 |
GO:0000119 | mediator complex | 0.0342893265491958 |
GO:0009892 | negative regulation of metabolic process | 0.0361207774297424 |
GO:0005496 | steroid binding | 0.0364892766763437 |
GO:0044444 | cytoplasmic part | 0.0364892766763437 |
GO:0003712 | transcription cofactor activity | 0.0366098248388845 |
GO:0016563 | transcription activator activity | 0.0378988578829624 |
GO:0006695 | cholesterol biosynthetic process | 0.0378988578829624 |
GO:0005795 | Golgi stack | 0.0378988578829624 |
GO:0008033 | tRNA processing | 0.0378988578829624 |
GO:0003723 | RNA binding | 0.0378988578829624 |
GO:0035026 | leading edge cell differentiation | 0.0378988578829624 |
GO:0048388 | endosomal lumen acidification | 0.0378988578829624 |
GO:0001667 | ameboidal cell migration | 0.0378988578829624 |
GO:0047757 | chondroitin-glucuronate 5-epimerase activity | 0.0378988578829624 |
GO:0000782 | telomere cap complex | 0.0378988578829624 |
GO:0035030 | phosphoinositide 3-kinase complex, class IA | 0.0378988578829624 |
GO:0000783 | nuclear telomere cap complex | 0.0378988578829624 |
GO:0008455 | alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity | 0.0378988578829624 |
GO:0004883 | glucocorticoid receptor activity | 0.0378988578829624 |
GO:0048244 | phytanoyl-CoA dioxygenase activity | 0.0378988578829624 |
GO:0032027 | myosin light chain binding | 0.0378988578829624 |
GO:0000902 | cell morphogenesis | 0.0415393574255019 |
GO:0032989 | cellular structure morphogenesis | 0.0415393574255019 |
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
hematopoietic system | 1.35e-07 | 98 |
blood island | 1.35e-07 | 98 |
Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 3.38387e-12 |
MA0004.1 | 0.319788 |
MA0006.1 | 2.29044 |
MA0007.1 | 0.109844 |
MA0009.1 | 0.336744 |
MA0014.1 | 1.3277e-08 |
MA0017.1 | 0.146224 |
MA0019.1 | 0.0798773 |
MA0024.1 | 0.727858 |
MA0025.1 | 1.69839 |
MA0027.1 | 0.609555 |
MA0028.1 | 0.529123 |
MA0029.1 | 0.124135 |
MA0030.1 | 1.31092 |
MA0031.1 | 1.6405 |
MA0038.1 | 0.0531477 |
MA0040.1 | 0.271054 |
MA0041.1 | 0.615139 |
MA0042.1 | 1.50122 |
MA0043.1 | 0.747453 |
MA0046.1 | 0.09141 |
MA0048.1 | 0.279112 |
MA0050.1 | 1.65908 |
MA0051.1 | 0.0475167 |
MA0052.1 | 0.0334873 |
MA0055.1 | 0.425572 |
MA0056.1 | 0 |
MA0057.1 | 0.0011776 |
MA0058.1 | 0.408481 |
MA0059.1 | 0.250499 |
MA0060.1 | 0.0535656 |
MA0061.1 | 0.580316 |
MA0063.1 | 0 |
MA0066.1 | 0.0749471 |
MA0067.1 | 0.293836 |
MA0068.1 | 0.00610087 |
MA0069.1 | 0.395337 |
MA0070.1 | 0.354713 |
MA0071.1 | 0.250553 |
MA0072.1 | 1.51713 |
MA0073.1 | 0 |
MA0074.1 | 0.156277 |
MA0076.1 | 1.58235 |
MA0077.1 | 0.543685 |
MA0078.1 | 1.65074 |
MA0081.1 | 1.11372 |
MA0083.1 | 0.115954 |
MA0084.1 | 0.300625 |
MA0087.1 | 0.108883 |
MA0088.1 | 4.61009e-05 |
MA0089.1 | 0 |
MA0090.1 | 0.00740648 |
MA0091.1 | 0.233426 |
MA0092.1 | 0.550476 |
MA0093.1 | 0.179969 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.504491 |
MA0101.1 | 0.807787 |
MA0103.1 | 0.192856 |
MA0105.1 | 0.116684 |
MA0106.1 | 0.0225875 |
MA0107.1 | 0.96256 |
MA0108.2 | 0.231806 |
MA0109.1 | 0 |
MA0111.1 | 0.242045 |
MA0113.1 | 0.374095 |
MA0114.1 | 0.0908675 |
MA0115.1 | 0.166507 |
MA0116.1 | 0.00973499 |
MA0117.1 | 1.94311 |
MA0119.1 | 0.222794 |
MA0122.1 | 0.436353 |
MA0124.1 | 0.456782 |
MA0125.1 | 0.0454401 |
MA0130.1 | 0 |
MA0131.1 | 1.03165 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 0.0542345 |
MA0136.1 | 1.72107 |
MA0139.1 | 0.0445146 |
MA0140.1 | 0.49841 |
MA0141.1 | 0.00176511 |
MA0142.1 | 0.274704 |
MA0143.1 | 0.375075 |
MA0144.1 | 0.169586 |
MA0145.1 | 1.10117e-07 |
MA0146.1 | 1.4721e-05 |
MA0147.1 | 0.00182141 |
MA0148.1 | 0.208529 |
MA0149.1 | 1.07353e-08 |
MA0062.2 | 3.68871 |
MA0035.2 | 0.234354 |
MA0039.2 | 5.47728e-09 |
MA0138.2 | 0.426589 |
MA0002.2 | 4.44099 |
MA0137.2 | 0.0639854 |
MA0104.2 | 0.00639888 |
MA0047.2 | 0.235525 |
MA0112.2 | 4.95146e-06 |
MA0065.2 | 1.64818e-05 |
MA0150.1 | 0.767069 |
MA0151.1 | 0 |
MA0152.1 | 0.0781848 |
MA0153.1 | 0.201045 |
MA0154.1 | 0.00570908 |
MA0155.1 | 1.29793e-05 |
MA0156.1 | 3.55786 |
MA0157.1 | 1.15527 |
MA0158.1 | 0 |
MA0159.1 | 0.000395184 |
MA0160.1 | 0.0901254 |
MA0161.1 | 0 |
MA0162.1 | 4.85301e-06 |
MA0163.1 | 9.99897e-12 |
MA0164.1 | 0.0977278 |
MA0080.2 | 2.69387 |
MA0018.2 | 4.31784 |
MA0099.2 | 0.0412662 |
MA0079.2 | 0 |
MA0102.2 | 0.184544 |
MA0258.1 | 0.0174365 |
MA0259.1 | 0.253253 |
MA0442.1 | 0 |
ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data
(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)
TF | #promoters | Enrichment | p-value | q-value |
---|---|---|---|---|
BATF#10538 | 64 | 2.03246325255206 | 1.09371172539299e-07 | 6.37067255372664e-06 |
BCL11A#53335 | 78 | 2.88502933257021 | 1.64022379248222e-16 | 3.26914756990554e-14 |
BCL3#602 | 42 | 1.89175791102609 | 8.56751201934674e-05 | 0.00128449955180671 |
BCLAF1#9774 | 68 | 1.91966106582566 | 3.40351641451693e-07 | 1.68864537204624e-05 |
BRCA1#672 | 70 | 1.84210709912081 | 9.84944292264352e-07 | 4.17647571822154e-05 |
CCNT2#905 | 157 | 1.29697998381113 | 0.000329883689894068 | 0.00336091334395147 |
CEBPB#1051 | 152 | 1.57967984240596 | 7.87787551786444e-09 | 6.08548403262015e-07 |
CHD2#1106 | 105 | 1.41606570740844 | 0.000201135151419087 | 0.00239116153432647 |
CTCF#10664 | 194 | 1.35578844377647 | 3.24930284579627e-06 | 0.000109046895858649 |
CTCFL#140690 | 59 | 1.51895956607495 | 0.00113653228816078 | 0.00778196391812912 |
E2F1#1869 | 231 | 1.47797510904449 | 1.04566831683246e-10 | 1.13052332651827e-08 |
E2F4#1874 | 85 | 1.40389195149828 | 0.00108561436015346 | 0.00765929056002618 |
E2F6#1876 | 220 | 1.43907987089104 | 3.95361688396425e-09 | 3.24106588496344e-07 |
EBF1#1879 | 192 | 2.22951973212679 | 8.79894825779481e-27 | 3.02287288518366e-24 |
EGR1#1958 | 224 | 1.45678242143086 | 8.84633747676367e-10 | 8.2712859421282e-08 |
ELF1#1997 | 311 | 1.72655601719576 | 6.55530514038116e-26 | 2.15292299860462e-23 |
ELK4#2005 | 70 | 1.48174408877805 | 0.000776827893804943 | 0.00608909699798067 |
EP300#2033 | 169 | 1.49256343120172 | 4.73172927183485e-08 | 3.07515291487965e-06 |
ETS1#2113 | 116 | 1.47136410296672 | 1.79643594058463e-05 | 0.000409288772248513 |
FOS#2353 | 127 | 1.48988308243754 | 3.6385265953531e-06 | 0.000119460571861705 |
FOSL1#8061 | 31 | 1.60511208762394 | 0.00776289904576527 | 0.0319242956938368 |
FOSL2#2355 | 64 | 1.41268948982001 | 0.00386430923663092 | 0.0190567849827414 |
FOXA1#3169 | 129 | 1.86375899305179 | 5.73780392445766e-12 | 7.45336447843823e-10 |
FOXA2#3170 | 58 | 1.86253832810246 | 6.2823113041017e-06 | 0.000185501359991257 |
GABPB1#2553 | 171 | 1.57571569229094 | 7.90832650876659e-10 | 7.46779124999163e-08 |
GATA1#2623 | 123 | 2.17459961106578 | 5.12783234953315e-16 | 9.9175126435721e-14 |
GATA2#2624 | 103 | 1.71150973736123 | 8.18139838769712e-08 | 4.88261180692971e-06 |
GTF2B#2959 | 54 | 2.24897890020014 | 4.98163435016177e-08 | 3.19188288280089e-06 |
GTF2F1#2962 | 102 | 1.69419218960793 | 1.54163595440607e-07 | 8.64234661525582e-06 |
HDAC8#55869 | 10 | 10.1249548059119 | 8.11629135605151e-08 | 4.85207414387329e-06 |
HEY1#23462 | 261 | 1.37479658702815 | 5.17990097594802e-09 | 4.15502056856402e-07 |
HMGN3#9324 | 136 | 1.45017273842983 | 6.10422627655217e-06 | 0.0001815776952711 |
HNF4A#3172 | 50 | 1.50797199236986 | 0.00304620481056376 | 0.0160694304581507 |
IRF1#3659 | 142 | 1.41392079922565 | 1.32828466925563e-05 | 0.000324350532084144 |
IRF4#3662 | 82 | 2.34288140849155 | 1.76548915291261e-12 | 2.4165913714422e-10 |
JUN#3725 | 111 | 1.81085272535767 | 1.14374388907224e-09 | 1.04966140624619e-07 |
JUNB#3726 | 40 | 1.59638240729185 | 0.00300413417965417 | 0.0159652335430949 |
JUND#3727 | 164 | 1.49559959122145 | 7.01607330078933e-08 | 4.25276656680868e-06 |
MAFF#23764 | 23 | 1.68872646580018 | 0.0117007348137291 | 0.0427142872246864 |
MAX#4149 | 223 | 1.87603634746882 | 1.27121898778693e-21 | 3.44843739910335e-19 |
MEF2A#4205 | 98 | 2.39483263252297 | 2.42228715712596e-15 | 4.38442371582457e-13 |
MEF2C#4208 | 37 | 1.99285543184757 | 8.08995317935978e-05 | 0.00122610161094058 |
MXI1#4601 | 170 | 2.20791026973804 | 5.02410743120218e-23 | 1.47806410142908e-20 |
MYC#4609 | 237 | 1.61366467219221 | 4.48240858107969e-15 | 7.9211213164024e-13 |
NFKB1#4790 | 312 | 2.23243257933309 | 1.04908077339574e-47 | 7.11460694108295e-45 |
NFYA#4800 | 64 | 1.53746696843436 | 0.000523251936251903 | 0.00453246321391827 |
NFYB#4801 | 77 | 1.68253465517902 | 7.52541198926354e-06 | 0.000214915641987064 |
NR3C1#2908 | 76 | 1.48363725315404 | 0.000447195172995914 | 0.00416150910385104 |
NRF1#4899 | 98 | 1.56011393204129 | 9.29675565791356e-06 | 0.000247626591215719 |
PAX5#5079 | 230 | 2.00000009409505 | 4.17518423075645e-26 | 1.3976027752435e-23 |
PBX3#5090 | 77 | 2.20002278602255 | 1.61552405150297e-10 | 1.69913108172123e-08 |
POLR2A#5430 | 560 | 1.56789280165909 | 3.23905362260889e-50 | 2.41631086636893e-47 |
POLR3A#11128 | 10 | 4.42153989689365 | 0.000115612221122936 | 0.0015721907242003 |
POU2F2#5452 | 175 | 2.07766846167528 | 5.85929631829075e-21 | 1.54530062673224e-18 |
RAD21#5885 | 103 | 1.39057169652151 | 0.000439019566733429 | 0.00409162631894277 |
REST#5978 | 112 | 1.40913065998219 | 0.000145495053283135 | 0.00188014821453073 |
RFX5#5993 | 143 | 2.24622066269739 | 7.2863875902966e-20 | 1.82053357306935e-17 |
SIN3A#25942 | 268 | 1.88993625395887 | 2.30864784163372e-27 | 8.22910825707796e-25 |
SMARCB1#6598 | 78 | 1.85620838452448 | 1.68424625674557e-07 | 9.28237439621375e-06 |
SMARCC1#6599 | 44 | 2.50480809656295 | 4.8501767795163e-08 | 3.14235491734431e-06 |
SMARCC2#6601 | 16 | 1.96412775857935 | 0.00912548236765572 | 0.0345222680115766 |
SP1#6667 | 220 | 1.63447705761538 | 1.92846074008846e-14 | 3.25900503615047e-12 |
SPI1#6688 | 188 | 2.01096847405772 | 4.42889250371759e-21 | 1.17696973077802e-18 |
SREBF1#6720 | 38 | 2.32884260591728 | 2.2105149795929e-06 | 7.92257975132816e-05 |
SRF#6722 | 114 | 2.05068881601973 | 3.45412307745709e-13 | 5.10970481708982e-11 |
STAT3#6774 | 94 | 1.28921735297588 | 0.00694316215900405 | 0.0293696602966474 |
TAF1#6872 | 368 | 1.60396484113985 | 5.78027931874556e-26 | 1.9164653706999e-23 |
TAL1#6886 | 52 | 2.02499096118239 | 1.95624954621317e-06 | 7.1939699421464e-05 |
TBP#6908 | 347 | 1.67698752075938 | 1.54031420315189e-27 | 5.56639706100278e-25 |
TCF12#6938 | 139 | 1.92723679452922 | 5.93140884869317e-14 | 9.559728530072e-12 |
TCF7L2#6934 | 101 | 1.41823707024364 | 0.000255007523573606 | 0.00274479344063731 |
TFAP2C#7022 | 92 | 1.296543718523 | 0.00652447997007745 | 0.02793351494609 |
THAP1#55145 | 38 | 1.55414275737725 | 0.00575076199781365 | 0.0259059624003476 |
TRIM28#10155 | 71 | 1.72089606025246 | 8.37202917142854e-06 | 0.00022949248153145 |
USF1#7391 | 161 | 1.33533426809711 | 6.53678146338592e-05 | 0.00106090896543055 |
USF2#7392 | 96 | 1.62614204558889 | 2.16864910086632e-06 | 7.83979035809547e-05 |
WRNIP1#56897 | 23 | 3.29316711869055 | 1.0289847315104e-06 | 4.32285343420009e-05 |
YY1#7528 | 260 | 1.66480364401826 | 1.46851145437133e-18 | 3.34868706949972e-16 |
ZBTB33#10009 | 36 | 1.48621916698738 | 0.0133427943491061 | 0.0471656151303535 |
ZEB1#6935 | 95 | 2.09178753802694 | 1.46306583860881e-11 | 1.79344052955945e-09 |
ZNF263#10127 | 124 | 1.32921559711776 | 0.000637966159250838 | 0.0052306914512481 |
Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data