Novel motif:127

name:	motif127_TTTTTACCCTC

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0031328	positive regulation of cellular biosynthetic process	3.362230e-17
GO:0045893	positive regulation of transcription, DNA-dependent	1.031575e-16
GO:0010557	positive regulation of macromolecule biosynthetic process	1.131333e-16
GO:0009891	positive regulation of biosynthetic process	1.728965e-16
GO:0051173	positive regulation of nitrogen compound metabolic process	7.324058e-15
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	9.193038e-15
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	1.690440e-14
GO:0051254	positive regulation of RNA metabolic process	2.384020e-14
GO:0010628	positive regulation of gene expression	3.927527e-14
GO:0031325	positive regulation of cellular metabolic process	1.263649e-13
GO:0090090	negative regulation of canonical Wnt receptor signaling pathway	2.327174e-12
GO:0009893	positive regulation of metabolic process	5.133284e-12
GO:0006357	regulation of transcription from RNA polymerase II promoter	9.269057e-12
GO:0010604	positive regulation of macromolecule metabolic process	3.021723e-11
GO:0060325	face morphogenesis	2.529057e-10
GO:0044334	canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition	6.801854e-10
GO:0010909	positive regulation of heparan sulfate proteoglycan biosynthetic process	6.801854e-10
GO:0060323	head morphogenesis	9.125118e-10
GO:0030178	negative regulation of Wnt receptor signaling pathway	1.898748e-9
GO:0033032	regulation of myeloid cell apoptosis	3.295367e-9
GO:0007417	central nervous system development	4.259458e-9
GO:0042762	regulation of sulfur metabolic process	6.307380e-9
GO:0051176	positive regulation of sulfur metabolic process	1.139101e-8
GO:0051100	negative regulation of binding	1.284724e-8
GO:0060324	face development	1.435781e-8
GO:0032330	regulation of chondrocyte differentiation	1.477406e-8
GO:0061035	regulation of cartilage development	1.554264e-8
GO:0060322	head development	1.919595e-8
GO:0007420	brain development	2.966380e-8
GO:0010171	body morphogenesis	3.301876e-8
GO:0032102	negative regulation of response to external stimulus	3.513340e-8
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	3.709208e-8
GO:0009888	tissue development	4.329715e-8
GO:0048557	embryonic digestive tract morphogenesis	7.205610e-8
GO:0070417	cellular response to cold	8.314958e-8
GO:0007626	locomotory behavior	8.495587e-8
GO:0043586	tongue development	1.072657e-7
GO:0035411	catenin import into nucleus	1.127858e-7
GO:0030538	embryonic genitalia morphogenesis	1.903986e-7
GO:0030522	intracellular receptor mediated signaling pathway	3.173178e-7
GO:2000027	regulation of organ morphogenesis	3.519016e-7
GO:0045165	cell fate commitment	4.507603e-7
GO:0048598	embryonic morphogenesis	4.971601e-7
GO:0032880	regulation of protein localization	5.285461e-7
GO:0043393	regulation of protein binding	5.405599e-7
GO:0050905	neuromuscular process	6.264278e-7
GO:0046545	development of primary female sexual characteristics	6.860816e-7
GO:0061198	fungiform papilla formation	7.166832e-7
GO:0032501	multicellular organismal process	7.279988e-7
GO:0032091	negative regulation of protein binding	7.993369e-7
GO:2000112	regulation of cellular macromolecule biosynthetic process	8.322045e-7
GO:2000370	positive regulation of clathrin-mediated endocytosis	8.995691e-7
GO:0048839	inner ear development	9.771539e-7
GO:0023052	signaling	1.106372e-6
GO:0060122	inner ear receptor stereocilium organization	1.128103e-6
GO:0045885	positive regulation of survival gene product expression	1.227874e-6
GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly	1.233303e-6
GO:0043401	steroid hormone mediated signaling pathway	1.384627e-6
GO:0050974	detection of mechanical stimulus involved in sensory perception	1.498928e-6
GO:0042489	negative regulation of odontogenesis of dentine-containing tooth	1.591360e-6
GO:0043570	maintenance of DNA repeat elements	1.637703e-6
GO:0048585	negative regulation of response to stimulus	1.854756e-6
GO:0061196	fungiform papilla development	1.858941e-6
GO:0033238	regulation of cellular amine metabolic process	1.914460e-6
GO:0071107	response to parathyroid hormone stimulus	1.957183e-6
GO:0060527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	1.964962e-6
GO:0008544	epidermis development	1.965328e-6
GO:0046660	female sex differentiation	1.992545e-6
GO:0010092	specification of organ identity	2.130739e-6
GO:0060443	mammary gland morphogenesis	2.440409e-6
GO:0046827	positive regulation of protein export from nucleus	2.933180e-6
GO:0007154	cell communication	3.161298e-6
GO:0033025	regulation of mast cell apoptosis	3.660094e-6
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	3.832710e-6
GO:0050982	detection of mechanical stimulus	4.054228e-6
GO:0032494	response to peptidoglycan	4.128216e-6
GO:0048332	mesoderm morphogenesis	4.462913e-6
GO:0010556	regulation of macromolecule biosynthetic process	4.794700e-6
GO:0048546	digestive tract morphogenesis	5.117158e-6
GO:0060119	inner ear receptor cell development	5.171463e-6
GO:0031326	regulation of cellular biosynthetic process	5.451291e-6
GO:0043583	ear development	5.548252e-6
GO:0060688	regulation of morphogenesis of a branching structure	6.010226e-6
GO:0006868	glutamine transport	6.012914e-6
GO:0033033	negative regulation of myeloid cell apoptosis	6.263451e-6
GO:0032495	response to muramyl dipeptide	6.332074e-6
GO:0018344	protein geranylgeranylation	6.336809e-6
GO:0032844	regulation of homeostatic process	6.872848e-6
GO:0070563	negative regulation of vitamin D receptor signaling pathway	7.614075e-6
GO:0035921	desmosome disassembly	7.614075e-6
GO:0043066	negative regulation of apoptosis	8.047945e-6
GO:0071383	cellular response to steroid hormone stimulus	8.072420e-6
GO:0007442	hindgut morphogenesis	8.095328e-6
GO:0050954	sensory perception of mechanical stimulus	8.101895e-6
GO:0043069	negative regulation of programmed cell death	8.231422e-6
GO:0022602	ovulation cycle process	9.281332e-6
GO:0007042	lysosomal lumen acidification	9.719046e-6
GO:0051971	positive regulation of transmission of nerve impulse	1.002499e-5
GO:0034197	triglyceride transport	1.015246e-5
GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway	1.038093e-5
GO:0022898	regulation of transmembrane transporter activity	1.055860e-5
GO:0001704	formation of primary germ layer	1.067318e-5
GO:0051098	regulation of binding	1.067490e-5
GO:0048333	mesodermal cell differentiation	1.070933e-5
GO:0009889	regulation of biosynthetic process	1.198437e-5
GO:0030514	negative regulation of BMP signaling pathway	1.227778e-5
GO:0048699	generation of neurons	1.262865e-5
GO:0010829	negative regulation of glucose transport	1.304342e-5
GO:0023051	regulation of signaling	1.314594e-5
GO:0048645	organ formation	1.351449e-5
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	1.391435e-5
GO:0009966	regulation of signal transduction	1.423508e-5
GO:0046325	negative regulation of glucose import	1.516426e-5
GO:0015980	energy derivation by oxidation of organic compounds	1.552630e-5
GO:0010648	negative regulation of cell communication	1.636839e-5
GO:0034339	regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	1.668222e-5
GO:0045637	regulation of myeloid cell differentiation	1.671971e-5
GO:0045842	positive regulation of mitotic metaphase/anaphase transition	1.700477e-5
GO:0008585	female gonad development	1.724018e-5
GO:0022612	gland morphogenesis	1.762735e-5
GO:0030900	forebrain development	1.806520e-5
GO:0008088	axon cargo transport	1.863595e-5
GO:0023057	negative regulation of signaling	1.974325e-5
GO:0006521	regulation of cellular amino acid metabolic process	2.005035e-5
GO:0009409	response to cold	2.027002e-5
GO:0009755	hormone-mediated signaling pathway	2.032707e-5
GO:0006355	regulation of transcription, DNA-dependent	2.118049e-5
GO:0050885	neuromuscular process controlling balance	2.136747e-5
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	2.172863e-5
GO:0048583	regulation of response to stimulus	2.254418e-5
GO:0043496	regulation of protein homodimerization activity	2.395293e-5
GO:0031646	positive regulation of neurological system process	2.404196e-5
GO:0048625	myoblast cell fate commitment	2.469138e-5
GO:0060341	regulation of cellular localization	2.487709e-5
GO:0010646	regulation of cell communication	2.535535e-5
GO:0045824	negative regulation of innate immune response	2.784593e-5
GO:0014739	positive regulation of muscle hyperplasia	2.791380e-5
GO:0048732	gland development	2.791841e-5
GO:0032412	regulation of ion transmembrane transporter activity	2.877661e-5
GO:0002051	osteoblast fate commitment	3.070894e-5
GO:0008090	retrograde axon cargo transport	3.118693e-5
GO:0051179	localization	3.246749e-5
GO:0030326	embryonic limb morphogenesis	3.391187e-5
GO:0046654	tetrahydrofolate biosynthetic process	3.528453e-5
GO:0009719	response to endogenous stimulus	3.648816e-5
GO:0070646	protein modification by small protein removal	3.831541e-5
GO:0010468	regulation of gene expression	3.921397e-5
GO:0007091	mitotic metaphase/anaphase transition	4.082480e-5
GO:0042698	ovulation cycle	4.221674e-5
GO:0042221	response to chemical stimulus	4.250338e-5
GO:0060173	limb development	4.258992e-5
GO:0051704	multi-organism process	4.283049e-5
GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	4.323910e-5
GO:0048511	rhythmic process	4.355467e-5
GO:0046209	nitric oxide metabolic process	4.356420e-5
GO:0007399	nervous system development	4.595289e-5
GO:0060117	auditory receptor cell development	4.814383e-5
GO:0060548	negative regulation of cell death	4.978784e-5
GO:0042832	defense response to protozoan	5.064683e-5
GO:0010565	regulation of cellular ketone metabolic process	5.149426e-5
GO:0048566	embryonic digestive tract development	5.326615e-5
GO:0001707	mesoderm formation	5.488456e-5
GO:0060789	hair follicle placode formation	5.854736e-5
GO:0045089	positive regulation of innate immune response	6.093281e-5
GO:0031000	response to caffeine	6.106242e-5
GO:0001562	response to protozoan	6.177365e-5
GO:0006554	lysine catabolic process	6.478261e-5
GO:0021861	forebrain radial glial cell differentiation	6.565050e-5
GO:0048518	positive regulation of biological process	6.724533e-5
GO:0051171	regulation of nitrogen compound metabolic process	6.726937e-5
GO:0042033	chemokine biosynthetic process	6.750590e-5
GO:0042253	granulocyte macrophage colony-stimulating factor biosynthetic process	6.750590e-5
GO:2000256	positive regulation of male germ cell proliferation	6.750590e-5
GO:0042231	interleukin-13 biosynthetic process	6.750590e-5
GO:0009653	anatomical structure morphogenesis	7.312528e-5
GO:0016579	protein deubiquitination	7.345835e-5
GO:0045666	positive regulation of neuron differentiation	7.395735e-5
GO:0070668	positive regulation of mast cell proliferation	7.584173e-5
GO:0048386	positive regulation of retinoic acid receptor signaling pathway	7.584173e-5
GO:0001928	regulation of exocyst assembly	7.628443e-5
GO:0060178	regulation of exocyst localization	7.628443e-5
GO:0016578	histone deubiquitination	7.632883e-5
GO:0043588	skin development	7.848702e-5
GO:0048806	genitalia development	7.867590e-5
GO:0060795	cell fate commitment involved in formation of primary germ layers	8.171167e-5
GO:2000612	regulation of thyroid-stimulating hormone secretion	8.212459e-5
GO:0048619	embryonic hindgut morphogenesis	8.324888e-5
GO:0022008	neurogenesis	8.337962e-5
GO:0042472	inner ear morphogenesis	8.692959e-5
GO:0071495	cellular response to endogenous stimulus	8.771045e-5
GO:0007253	cytoplasmic sequestering of NF-kappaB	8.778340e-5
GO:0071168	protein localization to chromatin	9.324428e-5
GO:0070201	regulation of establishment of protein localization	9.524997e-5
GO:0007165	signal transduction	9.559792e-5
GO:0061039	ovum-producing ovary development	9.981038e-5
GO:0001780	neutrophil homeostasis	1.001760e-4
GO:2000036	regulation of stem cell maintenance	1.023187e-4
GO:0006366	transcription from RNA polymerase II promoter	1.034168e-4
GO:2000736	regulation of stem cell differentiation	1.043381e-4
GO:0051239	regulation of multicellular organismal process	1.045406e-4
GO:0048646	anatomical structure formation involved in morphogenesis	1.056589e-4
GO:0046883	regulation of hormone secretion	1.056997e-4
GO:0010559	regulation of glycoprotein biosynthetic process	1.072789e-4
GO:0051726	regulation of cell cycle	1.084961e-4
GO:0051223	regulation of protein transport	1.086051e-4
GO:0072278	metanephric comma-shaped body morphogenesis	1.097277e-4
GO:0032722	positive regulation of chemokine production	1.124749e-4
GO:0035129	post-embryonic hindlimb morphogenesis	1.128978e-4
GO:0035108	limb morphogenesis	1.152521e-4
GO:0002251	organ or tissue specific immune response	1.156201e-4
GO:0071363	cellular response to growth factor stimulus	1.156807e-4
GO:0060011	Sertoli cell proliferation	1.185746e-4
GO:0051252	regulation of RNA metabolic process	1.187124e-4
GO:0032649	regulation of interferon-gamma production	1.191623e-4
GO:0010501	RNA secondary structure unwinding	1.208597e-4
GO:0045779	negative regulation of bone resorption	1.224848e-4
GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation	1.289606e-4
GO:0031348	negative regulation of defense response	1.299520e-4
GO:0046851	negative regulation of bone remodeling	1.319780e-4
GO:0044247	cellular polysaccharide catabolic process	1.322369e-4
GO:0009251	glucan catabolic process	1.322369e-4
GO:0042416	dopamine biosynthetic process	1.342569e-4
GO:0031623	receptor internalization	1.353713e-4
GO:0010985	negative regulation of lipoprotein particle clearance	1.383391e-4
GO:0060113	inner ear receptor cell differentiation	1.390541e-4
GO:0000079	regulation of cyclin-dependent protein kinase activity	1.404654e-4
GO:0006351	transcription, DNA-dependent	1.415504e-4
GO:0009968	negative regulation of signal transduction	1.422648e-4
GO:0002221	pattern recognition receptor signaling pathway	1.429527e-4
GO:0019219	regulation of nucleobase-containing compound metabolic process	1.473398e-4
GO:0060749	mammary gland alveolus development	1.474845e-4
GO:0042483	negative regulation of odontogenesis	1.485772e-4
GO:0033693	neurofilament bundle assembly	1.485772e-4
GO:0071477	cellular hypotonic salinity response	1.506068e-4
GO:0060580	ventral spinal cord interneuron fate determination	1.506068e-4
GO:0003327	type B pancreatic cell fate commitment	1.506068e-4
GO:0048468	cell development	1.545830e-4
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	1.550293e-4
GO:0042471	ear morphogenesis	1.587316e-4
GO:0071374	cellular response to parathyroid hormone stimulus	1.595102e-4
GO:0007605	sensory perception of sound	1.633621e-4
GO:0065007	biological regulation	1.662624e-4
GO:0021536	diencephalon development	1.668543e-4
GO:0018243	protein O-linked glycosylation via threonine	1.674996e-4
GO:0071895	odontoblast differentiation	1.674996e-4
GO:0018242	protein O-linked glycosylation via serine	1.674996e-4
GO:0070838	divalent metal ion transport	1.677265e-4
GO:0071866	negative regulation of apoptosis in bone marrow	1.691661e-4
GO:0071864	positive regulation of cell proliferation in bone marrow	1.691661e-4
GO:0090316	positive regulation of intracellular protein transport	1.719855e-4
GO:0060603	mammary gland duct morphogenesis	1.728877e-4
GO:0045200	establishment of neuroblast polarity	1.741729e-4
GO:0002175	protein localization to paranode region of axon	1.741729e-4
GO:0010837	regulation of keratinocyte proliferation	1.768431e-4
GO:0005980	glycogen catabolic process	1.811384e-4
GO:0048565	digestive tract development	1.839989e-4
GO:0070346	positive regulation of fat cell proliferation	1.858182e-4
GO:0006313	transposition, DNA-mediated	1.858182e-4
GO:0032642	regulation of chemokine production	1.866307e-4
GO:0032413	negative regulation of ion transmembrane transporter activity	1.877055e-4
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	1.889535e-4
GO:0007369	gastrulation	1.943931e-4
GO:0018342	protein prenylation	1.958319e-4
GO:0042490	mechanoreceptor differentiation	1.958439e-4
GO:0060594	mammary gland specification	1.969600e-4
GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	1.986921e-4
GO:0051924	regulation of calcium ion transport	1.989682e-4
GO:0014033	neural crest cell differentiation	2.024891e-4
GO:0042994	cytoplasmic sequestering of transcription factor	2.042378e-4
GO:0043921	modulation by host of viral transcription	2.056245e-4
GO:0010984	regulation of lipoprotein particle clearance	2.089598e-4
GO:0030182	neuron differentiation	2.149390e-4
GO:0072511	divalent inorganic cation transport	2.155335e-4
GO:0035545	determination of left/right asymmetry in nervous system	2.196382e-4
GO:0061302	smooth muscle cell-matrix adhesion	2.196382e-4
GO:0045884	regulation of survival gene product expression	2.199955e-4
GO:0050884	neuromuscular process controlling posture	2.225641e-4
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	2.325538e-4
GO:0050877	neurological system process	2.338579e-4
GO:0022904	respiratory electron transport chain	2.352767e-4
GO:0070536	protein K63-linked deubiquitination	2.417718e-4
GO:0060019	radial glial cell differentiation	2.430106e-4
GO:0016198	axon choice point recognition	2.518857e-4
GO:0060255	regulation of macromolecule metabolic process	2.579875e-4
GO:0046716	muscle cell homeostasis	2.605047e-4
GO:0032088	negative regulation of NF-kappaB transcription factor activity	2.643078e-4
GO:0014074	response to purine-containing compound	2.648306e-4
GO:0055085	transmembrane transport	2.668007e-4
GO:0044060	regulation of endocrine process	2.678708e-4
GO:0031323	regulation of cellular metabolic process	2.688676e-4
GO:0033151	V(D)J recombination	2.698005e-4
GO:0072358	cardiovascular system development	2.750698e-4
GO:0030213	hyaluronan biosynthetic process	2.773767e-4
GO:0007610	behavior	2.805485e-4
GO:0010633	negative regulation of epithelial cell migration	2.817896e-4
GO:0060788	ectodermal placode formation	2.866755e-4
GO:0002758	innate immune response-activating signal transduction	2.915632e-4
GO:0010747	positive regulation of plasma membrane long-chain fatty acid transport	2.961101e-4
GO:0001541	ovarian follicle development	2.970648e-4
GO:0048513	organ development	2.984111e-4
GO:2000026	regulation of multicellular organismal development	3.049556e-4
GO:0060690	epithelial cell differentiation involved in salivary gland development	3.099405e-4
GO:0072003	kidney rudiment formation	3.183049e-4
GO:0060052	neurofilament cytoskeleton organization	3.235532e-4
GO:0048385	regulation of retinoic acid receptor signaling pathway	3.258907e-4
GO:0060849	regulation of transcription involved in lymphatic endothelial cell fate commitment	3.288274e-4
GO:0007565	female pregnancy	3.331161e-4
GO:0048709	oligodendrocyte differentiation	3.337001e-4
GO:0045088	regulation of innate immune response	3.356239e-4
GO:2000104	negative regulation of DNA-dependent DNA replication	3.381344e-4
GO:0060088	auditory receptor cell stereocilium organization	3.381344e-4
GO:0050806	positive regulation of synaptic transmission	3.410226e-4
GO:0006809	nitric oxide biosynthetic process	3.417540e-4
GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	3.461121e-4
GO:0070375	BMK cascade	3.490407e-4
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	3.490407e-4
GO:0021827	postnatal olfactory bulb interneuron migration	3.490407e-4
GO:0010988	regulation of low-density lipoprotein particle clearance	3.503737e-4
GO:0044091	membrane biogenesis	3.512964e-4
GO:0003008	system process	3.542609e-4
GO:0006638	neutral lipid metabolic process	3.553022e-4
GO:0006816	calcium ion transport	3.582186e-4
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	3.594716e-4
GO:0048729	tissue morphogenesis	3.634697e-4
GO:0014032	neural crest cell development	3.642289e-4
GO:0007275	multicellular organismal development	3.703051e-4
GO:0032729	positive regulation of interferon-gamma production	3.707916e-4
GO:0070848	response to growth factor stimulus	3.860065e-4
GO:0043392	negative regulation of DNA binding	3.874841e-4
GO:0072305	negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis	3.924207e-4
GO:2000594	positive regulation of metanephric DCT cell differentiation	3.924207e-4
GO:0039003	pronephric field specification	3.924207e-4
GO:0007498	mesoderm development	4.003093e-4
GO:0071899	negative regulation of estrogen receptor binding	4.055218e-4
GO:2000573	positive regulation of DNA biosynthetic process	4.137892e-4
GO:0051066	dihydrobiopterin metabolic process	4.137892e-4
GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	4.144114e-4
GO:0055080	cation homeostasis	4.186501e-4
GO:0021530	spinal cord oligodendrocyte cell fate specification	4.258101e-4
GO:0001568	blood vessel development	4.265008e-4
GO:0006639	acylglycerol metabolic process	4.287878e-4
GO:0007166	cell surface receptor linked signaling pathway	4.293161e-4
GO:0002093	auditory receptor cell morphogenesis	4.294357e-4
GO:0035330	regulation of hippo signaling cascade	4.389550e-4
GO:2000241	regulation of reproductive process	4.431286e-4
GO:0032703	negative regulation of interleukin-2 production	4.468499e-4
GO:0046677	response to antibiotic	4.561682e-4
GO:0033153	T cell receptor V(D)J recombination	4.654281e-4
GO:0031657	regulation of cyclin-dependent protein kinase activity involved in G1/S	4.674962e-4
GO:0090068	positive regulation of cell cycle process	4.793831e-4
GO:0030223	neutrophil differentiation	4.833151e-4
GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis	4.844645e-4
GO:0010033	response to organic substance	4.883856e-4
GO:0032331	negative regulation of chondrocyte differentiation	4.888274e-4
GO:0051145	smooth muscle cell differentiation	4.932021e-4
GO:0090276	regulation of peptide hormone secretion	4.966583e-4
GO:0048856	anatomical structure development	4.971951e-4
GO:0050883	musculoskeletal movement, spinal reflex action	4.981109e-4
GO:0006571	tyrosine biosynthetic process	4.981109e-4
GO:0071560	cellular response to transforming growth factor beta stimulus	4.996292e-4
GO:0061029	eyelid development in camera-type eye	5.023336e-4
GO:0022410	circadian sleep/wake cycle process	5.023336e-4
GO:0032226	positive regulation of synaptic transmission, dopaminergic	5.023824e-4
GO:0048341	paraxial mesoderm formation	5.040217e-4
GO:0048522	positive regulation of cellular process	5.053898e-4
GO:0015789	UDP-N-acetylgalactosamine transport	5.110631e-4
GO:0015787	UDP-glucuronic acid transport	5.110631e-4
GO:0002757	immune response-activating signal transduction	5.159186e-4
GO:0090361	regulation of platelet-derived growth factor production	5.166459e-4
GO:0072221	metanephric distal convoluted tubule development	5.266593e-4
GO:0032388	positive regulation of intracellular transport	5.312283e-4
GO:0032409	regulation of transporter activity	5.317717e-4
GO:0060523	prostate epithelial cord elongation	5.356898e-4
GO:0051241	negative regulation of multicellular organismal process	5.368275e-4
GO:0032876	negative regulation of DNA endoreduplication	5.463902e-4
GO:0002384	hepatic immune response	5.463902e-4
GO:0007379	segment specification	5.473095e-4
GO:0010632	regulation of epithelial cell migration	5.538149e-4
GO:0031394	positive regulation of prostaglandin biosynthetic process	5.541477e-4
GO:0071310	cellular response to organic substance	5.641169e-4
GO:0090074	negative regulation of protein homodimerization activity	5.641435e-4
GO:0009790	embryo development	5.642367e-4
GO:0060525	prostate glandular acinus development	5.643926e-4
GO:0045638	negative regulation of myeloid cell differentiation	5.740469e-4
GO:0060745	mammary gland branching involved in pregnancy	5.970237e-4
GO:0051480	cytosolic calcium ion homeostasis	6.051941e-4
GO:0048066	developmental pigmentation	6.056776e-4
GO:0043201	response to leucine	6.076619e-4
GO:0048512	circadian behavior	6.231391e-4
GO:0030879	mammary gland development	6.339540e-4
GO:0032092	positive regulation of protein binding	6.344348e-4
GO:0003002	regionalization	6.347224e-4
GO:0032386	regulation of intracellular transport	6.378867e-4
GO:0007204	elevation of cytosolic calcium ion concentration	6.424767e-4
GO:0032108	negative regulation of response to nutrient levels	6.461325e-4
GO:0021535	cell migration in hindbrain	6.583052e-4
GO:0060839	endothelial cell fate commitment	6.643097e-4
GO:0046146	tetrahydrobiopterin metabolic process	6.643097e-4
GO:0001944	vasculature development	6.659447e-4
GO:0002639	positive regulation of immunoglobulin production	6.678858e-4
GO:0032870	cellular response to hormone stimulus	6.743550e-4
GO:0080090	regulation of primary metabolic process	6.883955e-4
GO:0007214	gamma-aminobutyric acid signaling pathway	6.992599e-4
GO:0048713	regulation of oligodendrocyte differentiation	6.996494e-4
GO:0015721	bile acid and bile salt transport	7.053311e-4
GO:0043112	receptor metabolic process	7.092501e-4
GO:2000659	regulation of interleukin-1-mediated signaling pathway	7.137859e-4
GO:0048280	vesicle fusion with Golgi apparatus	7.188364e-4
GO:0010989	negative regulation of low-density lipoprotein particle clearance	7.188364e-4
GO:0072378	blood coagulation, fibrin clot formation	7.190071e-4
GO:0051058	negative regulation of small GTPase mediated signal transduction	7.207164e-4
GO:0032981	mitochondrial respiratory chain complex I assembly	7.299096e-4
GO:0001503	ossification	7.483240e-4
GO:0015820	leucine transport	7.488667e-4
GO:0008612	peptidyl-lysine modification to hypusine	7.488667e-4
GO:0032774	RNA biosynthetic process	7.519094e-4
GO:0032502	developmental process	7.776555e-4
GO:0035112	genitalia morphogenesis	7.779658e-4
GO:0045727	positive regulation of translation	7.943890e-4
GO:0006641	triglyceride metabolic process	8.064742e-4
GO:0007389	pattern specification process	8.173973e-4
GO:0070365	hepatocyte differentiation	8.341299e-4
GO:0045333	cellular respiration	8.366893e-4
GO:0034762	regulation of transmembrane transport	8.428968e-4
GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	8.471115e-4
GO:0042745	circadian sleep/wake cycle	8.575307e-4
GO:0048660	regulation of smooth muscle cell proliferation	8.586321e-4
GO:0044344	cellular response to fibroblast growth factor stimulus	8.641565e-4
GO:0009068	aspartate family amino acid catabolic process	8.664911e-4
GO:0045639	positive regulation of myeloid cell differentiation	8.700142e-4
GO:0060828	regulation of canonical Wnt receptor signaling pathway	8.803232e-4
GO:0030854	positive regulation of granulocyte differentiation	8.942086e-4
GO:0043490	malate-aspartate shuttle	8.949530e-4
GO:0048666	neuron development	8.999729e-4
GO:0007494	midgut development	9.034617e-4
GO:0072017	distal tubule development	9.084669e-4
GO:0045356	positive regulation of interferon-alpha biosynthetic process	9.086646e-4
GO:0045110	intermediate filament bundle assembly	9.086646e-4
GO:0002764	immune response-regulating signaling pathway	9.107540e-4
GO:0031349	positive regulation of defense response	9.189094e-4
GO:0050931	pigment cell differentiation	9.282091e-4
GO:0042095	interferon-gamma biosynthetic process	9.284159e-4
GO:0033627	cell adhesion mediated by integrin	9.436182e-4
GO:0001655	urogenital system development	9.477201e-4
GO:0008543	fibroblast growth factor receptor signaling pathway	9.722688e-4
GO:0030111	regulation of Wnt receptor signaling pathway	9.767573e-4
GO:0002036	regulation of L-glutamate transport	9.788682e-4
GO:0010467	gene expression	9.966951e-4
GO:0010243	response to organic nitrogen	1.007635e-3
GO:0040008	regulation of growth	1.048109e-3
GO:0006885	regulation of pH	1.083388e-3
GO:0032965	regulation of collagen biosynthetic process	1.095751e-3
GO:0006111	regulation of gluconeogenesis	1.095751e-3
GO:0001525	angiogenesis	1.127994e-3
GO:0060068	vagina development	1.135612e-3
GO:0048731	system development	1.142105e-3
GO:0071985	multivesicular body sorting pathway	1.163589e-3
GO:0007622	rhythmic behavior	1.164466e-3
GO:0042491	auditory receptor cell differentiation	1.173710e-3
GO:0000052	citrulline metabolic process	1.186282e-3
GO:0048087	positive regulation of developmental pigmentation	1.193257e-3
GO:0035987	endodermal cell differentiation	1.193257e-3
GO:0046580	negative regulation of Ras protein signal transduction	1.194168e-3
GO:0002791	regulation of peptide secretion	1.205737e-3
GO:0051925	regulation of calcium ion transport via voltage-gated calcium channel activity	1.218967e-3
GO:0034104	negative regulation of tissue remodeling	1.228776e-3
GO:0048878	chemical homeostasis	1.260233e-3
GO:0043523	regulation of neuron apoptosis	1.262599e-3
GO:0016070	RNA metabolic process	1.279956e-3
GO:0033629	negative regulation of cell adhesion mediated by integrin	1.286212e-3
GO:0007597	blood coagulation, intrinsic pathway	1.294833e-3
GO:0010560	positive regulation of glycoprotein biosynthetic process	1.297594e-3
GO:0048880	sensory system development	1.297976e-3
GO:0032879	regulation of localization	1.345682e-3
GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	1.367815e-3
GO:0048496	maintenance of organ identity	1.403992e-3
GO:0045063	T-helper 1 cell differentiation	1.408958e-3
GO:0051046	regulation of secretion	1.426044e-3
GO:0048562	embryonic organ morphogenesis	1.427963e-3
GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	1.428473e-3
GO:0048762	mesenchymal cell differentiation	1.430513e-3
GO:0033157	regulation of intracellular protein transport	1.447286e-3
GO:0031989	bombesin receptor signaling pathway	1.454749e-3
GO:0032854	positive regulation of Rap GTPase activity	1.465520e-3
GO:0006073	cellular glucan metabolic process	1.480601e-3
GO:0030518	steroid hormone receptor signaling pathway	1.498740e-3
GO:0010897	negative regulation of triglyceride catabolic process	1.499260e-3
GO:0010987	negative regulation of high-density lipoprotein particle clearance	1.499260e-3
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	1.514120e-3
GO:0002262	myeloid cell homeostasis	1.528365e-3
GO:0032768	regulation of monooxygenase activity	1.534895e-3
GO:0019896	axon transport of mitochondrion	1.542120e-3
GO:2000366	positive regulation of STAT protein import into nucleus	1.554471e-3
GO:0070091	glucagon secretion	1.554471e-3
GO:0008154	actin polymerization or depolymerization	1.567988e-3
GO:0021510	spinal cord development	1.571124e-3
GO:0048008	platelet-derived growth factor receptor signaling pathway	1.571900e-3
GO:0021932	hindbrain radial glia guided cell migration	1.583576e-3
GO:0051088	PMA-inducible membrane protein ectodomain proteolysis	1.587882e-3
GO:0006097	glyoxylate cycle	1.587882e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0050789	regulation of biological process	1.699785e-12
GO:0050794	regulation of cellular process	3.546506e-12
GO:0048732	gland development	8.436334e-12
GO:0007165	signal transduction	1.196871e-10
GO:0007275	multicellular organismal development	2.182688e-10
GO:0051716	cellular response to stimulus	2.297441e-10
GO:0050896	response to stimulus	2.409117e-10
GO:0048731	system development	3.089972e-10
GO:0023052	signaling	3.769693e-10
GO:0031326	regulation of cellular biosynthetic process	4.556436e-10
GO:0048518	positive regulation of biological process	4.899847e-10
GO:0032501	multicellular organismal process	6.165244e-10
GO:0048522	positive regulation of cellular process	9.669386e-10
GO:0051050	positive regulation of transport	1.050895e-9
GO:0065007	biological regulation	1.100630e-9
GO:0001655	urogenital system development	1.135042e-9
GO:0009889	regulation of biosynthetic process	1.244103e-9
GO:0010646	regulation of cell communication	1.533910e-9
GO:0048513	organ development	3.004004e-9
GO:0009888	tissue development	3.012636e-9
GO:0009605	response to external stimulus	4.406526e-9
GO:0048869	cellular developmental process	5.301242e-9
GO:0043409	negative regulation of MAPKKK cascade	5.822222e-9
GO:0014911	positive regulation of smooth muscle cell migration	6.250193e-9
GO:0030154	cell differentiation	7.537031e-9
GO:0071670	smooth muscle cell chemotaxis	8.283529e-9
GO:0060981	cell migration involved in coronary angiogenesis	8.283529e-9
GO:0016579	protein deubiquitination	9.144772e-9
GO:0022612	gland morphogenesis	1.288603e-8
GO:0046883	regulation of hormone secretion	1.307428e-8
GO:0051047	positive regulation of secretion	1.403414e-8
GO:2000573	positive regulation of DNA biosynthetic process	1.451801e-8
GO:0031323	regulation of cellular metabolic process	1.753004e-8
GO:0072203	cell proliferation involved in metanephros development	1.771845e-8
GO:0032502	developmental process	1.863477e-8
GO:0035270	endocrine system development	2.416018e-8
GO:2000112	regulation of cellular macromolecule biosynthetic process	3.314032e-8
GO:0060255	regulation of macromolecule metabolic process	3.497598e-8
GO:0048856	anatomical structure development	3.859592e-8
GO:0031167	rRNA methylation	3.996720e-8
GO:0007154	cell communication	4.278871e-8
GO:0010647	positive regulation of cell communication	4.361905e-8
GO:0010556	regulation of macromolecule biosynthetic process	4.644082e-8
GO:0002244	hemopoietic progenitor cell differentiation	5.054866e-8
GO:0007399	nervous system development	5.930153e-8
GO:0030850	prostate gland development	6.073904e-8
GO:0019222	regulation of metabolic process	6.210780e-8
GO:0061302	smooth muscle cell-matrix adhesion	6.630888e-8
GO:0046887	positive regulation of hormone secretion	7.045989e-8
GO:0051171	regulation of nitrogen compound metabolic process	7.516191e-8
GO:0001818	negative regulation of cytokine production	7.876271e-8
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	8.859765e-8
GO:0051240	positive regulation of multicellular organismal process	1.079500e-7
GO:0048699	generation of neurons	1.350311e-7
GO:0023056	positive regulation of signaling	1.404333e-7
GO:0051252	regulation of RNA metabolic process	1.456180e-7
GO:0080090	regulation of primary metabolic process	1.456424e-7
GO:0022008	neurogenesis	1.649300e-7
GO:0002320	lymphoid progenitor cell differentiation	1.655656e-7
GO:0007417	central nervous system development	2.529966e-7
GO:0023051	regulation of signaling	2.642271e-7
GO:0030182	neuron differentiation	2.814288e-7
GO:0072111	cell proliferation involved in kidney development	3.270971e-7
GO:0000154	rRNA modification	3.329572e-7
GO:0014910	regulation of smooth muscle cell migration	3.636539e-7
GO:0003050	regulation of systemic arterial blood pressure by atrial natriuretic peptide	3.928261e-7
GO:0070887	cellular response to chemical stimulus	4.077742e-7
GO:0009967	positive regulation of signal transduction	4.208808e-7
GO:0006935	chemotaxis	4.427083e-7
GO:0070372	regulation of ERK1 and ERK2 cascade	4.746637e-7
GO:0001501	skeletal system development	4.961591e-7
GO:0042330	taxis	5.667412e-7
GO:0048584	positive regulation of response to stimulus	6.417091e-7
GO:0010627	regulation of intracellular protein kinase cascade	6.548530e-7
GO:0007166	cell surface receptor linked signaling pathway	6.780994e-7
GO:0032879	regulation of localization	6.957774e-7
GO:0051049	regulation of transport	7.000919e-7
GO:0006355	regulation of transcription, DNA-dependent	7.176318e-7
GO:0035904	aorta development	8.263059e-7
GO:0030282	bone mineralization	8.921744e-7
GO:0060429	epithelium development	9.155804e-7
GO:0090068	positive regulation of cell cycle process	1.089142e-6
GO:0048583	regulation of response to stimulus	1.148814e-6
GO:0002009	morphogenesis of an epithelium	1.216284e-6
GO:0072001	renal system development	1.222081e-6
GO:0060840	artery development	1.280047e-6
GO:0030879	mammary gland development	1.506941e-6
GO:0048660	regulation of smooth muscle cell proliferation	1.645334e-6
GO:0035239	tube morphogenesis	1.675209e-6
GO:0051896	regulation of protein kinase B signaling cascade	1.724361e-6
GO:0060012	synaptic transmission, glycinergic	1.797401e-6
GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	1.974296e-6
GO:0072006	nephron development	2.133658e-6
GO:0000188	inactivation of MAPK activity	2.141698e-6
GO:0051897	positive regulation of protein kinase B signaling cascade	2.172069e-6
GO:0009893	positive regulation of metabolic process	2.244002e-6
GO:0009653	anatomical structure morphogenesis	2.271161e-6
GO:0019219	regulation of nucleobase-containing compound metabolic process	2.306748e-6
GO:0070373	negative regulation of ERK1 and ERK2 cascade	2.310981e-6
GO:0051239	regulation of multicellular organismal process	2.432315e-6
GO:0021940	positive regulation of cerebellar granule cell precursor proliferation	2.479863e-6
GO:0031325	positive regulation of cellular metabolic process	2.546874e-6
GO:0008284	positive regulation of cell proliferation	2.547326e-6
GO:0003002	regionalization	2.547805e-6
GO:0034261	negative regulation of Ras GTPase activity	2.557440e-6
GO:0043407	negative regulation of MAP kinase activity	2.798403e-6
GO:0042327	positive regulation of phosphorylation	3.135711e-6
GO:0016070	RNA metabolic process	3.183793e-6
GO:0010468	regulation of gene expression	3.305303e-6
GO:0070646	protein modification by small protein removal	3.412113e-6
GO:0072070	loop of Henle development	3.670894e-6
GO:0060978	angiogenesis involved in coronary vascular morphogenesis	3.715839e-6
GO:0003006	developmental process involved in reproduction	3.742573e-6
GO:0048608	reproductive structure development	3.838862e-6
GO:0032774	RNA biosynthetic process	4.002784e-6
GO:0072073	kidney epithelium development	4.131832e-6
GO:0031018	endocrine pancreas development	4.323978e-6
GO:0043148	mitotic spindle stabilization	4.723620e-6
GO:0090276	regulation of peptide hormone secretion	4.929977e-6
GO:0006351	transcription, DNA-dependent	4.978425e-6
GO:0043032	positive regulation of macrophage activation	4.981963e-6
GO:0043303	mast cell degranulation	5.341625e-6
GO:0060442	branching involved in prostate gland morphogenesis	5.414849e-6
GO:0010595	positive regulation of endothelial cell migration	5.668267e-6
GO:0010741	negative regulation of intracellular protein kinase cascade	5.824933e-6
GO:0072009	nephron epithelium development	6.021565e-6
GO:0060512	prostate gland morphogenesis	6.308111e-6
GO:0072080	nephron tubule development	6.419793e-6
GO:0072176	nephric duct development	7.487632e-6
GO:0021936	regulation of cerebellar granule cell precursor proliferation	7.641181e-6
GO:0045937	positive regulation of phosphate metabolic process	7.935585e-6
GO:0032695	negative regulation of interleukin-12 production	8.003224e-6
GO:0015939	pantothenate metabolic process	8.239414e-6
GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	8.296435e-6
GO:0051602	response to electrical stimulus	8.820139e-6
GO:0043374	CD8-positive, alpha-beta T cell differentiation	8.871628e-6
GO:0072017	distal tubule development	9.028767e-6
GO:0042127	regulation of cell proliferation	9.077567e-6
GO:0072178	nephric duct morphogenesis	9.125763e-6
GO:0060443	mammary gland morphogenesis	9.393985e-6
GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	9.497476e-6
GO:0030518	steroid hormone receptor signaling pathway	9.747979e-6
GO:0007548	sex differentiation	1.011431e-5
GO:0009891	positive regulation of biosynthetic process	1.011907e-5
GO:0060244	negative regulation of cell proliferation involved in contact inhibition	1.049329e-5
GO:0032270	positive regulation of cellular protein metabolic process	1.057678e-5
GO:2000045	regulation of G1/S transition of mitotic cell cycle	1.077912e-5
GO:0009952	anterior/posterior pattern specification	1.086542e-5
GO:0002520	immune system development	1.106786e-5
GO:0021985	neurohypophysis development	1.114840e-5
GO:0071158	positive regulation of cell cycle arrest	1.214631e-5
GO:0035674	tricarboxylic acid transmembrane transport	1.215115e-5
GO:0048096	chromatin-mediated maintenance of transcription	1.227707e-5
GO:0043414	macromolecule methylation	1.260272e-5
GO:0060259	regulation of feeding behavior	1.307485e-5
GO:0031401	positive regulation of protein modification process	1.338106e-5
GO:0009966	regulation of signal transduction	1.341058e-5
GO:0061326	renal tubule development	1.462578e-5
GO:0048534	hemopoietic or lymphoid organ development	1.603946e-5
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.610556e-5
GO:0060740	prostate gland epithelium morphogenesis	1.631155e-5
GO:2000507	positive regulation of energy homeostasis	1.638037e-5
GO:2000253	positive regulation of feeding behavior	1.638037e-5
GO:2000756	regulation of peptidyl-lysine acetylation	1.647908e-5
GO:0007346	regulation of mitotic cell cycle	1.660649e-5
GO:0060690	epithelial cell differentiation involved in salivary gland development	1.757039e-5
GO:0048729	tissue morphogenesis	1.816402e-5
GO:0032911	negative regulation of transforming growth factor beta1 production	1.845736e-5
GO:0071363	cellular response to growth factor stimulus	1.872030e-5
GO:0048589	developmental growth	1.887816e-5
GO:0048485	sympathetic nervous system development	2.011533e-5
GO:0031328	positive regulation of cellular biosynthetic process	2.107245e-5
GO:0030513	positive regulation of BMP signaling pathway	2.195110e-5
GO:0007420	brain development	2.228653e-5
GO:0060326	cell chemotaxis	2.240177e-5
GO:0030097	hemopoiesis	2.259315e-5
GO:0048598	embryonic morphogenesis	2.272034e-5
GO:0010226	response to lithium ion	2.313592e-5
GO:0071478	cellular response to radiation	2.329600e-5
GO:0032203	telomere formation via telomerase	2.361640e-5
GO:0016477	cell migration	2.392035e-5
GO:0002791	regulation of peptide secretion	2.428726e-5
GO:0001822	kidney development	2.524415e-5
GO:0007389	pattern specification process	2.587207e-5
GO:0044260	cellular macromolecule metabolic process	2.689364e-5
GO:0043170	macromolecule metabolic process	2.693516e-5
GO:0042221	response to chemical stimulus	2.707963e-5
GO:0072277	metanephric glomerular capillary formation	2.769775e-5
GO:2000602	regulation of interphase of mitotic cell cycle	2.795394e-5
GO:2000147	positive regulation of cell motility	2.859230e-5
GO:0048013	ephrin receptor signaling pathway	2.888260e-5
GO:0051241	negative regulation of multicellular organismal process	2.994447e-5
GO:0060164	regulation of timing of neuron differentiation	3.204753e-5
GO:0051046	regulation of secretion	3.320286e-5
GO:0014068	positive regulation of phosphatidylinositol 3-kinase cascade	3.356513e-5
GO:0006479	protein methylation	3.403415e-5
GO:0090277	positive regulation of peptide hormone secretion	3.573533e-5
GO:0010604	positive regulation of macromolecule metabolic process	3.674089e-5
GO:0050796	regulation of insulin secretion	3.748067e-5
GO:0035909	aorta morphogenesis	3.800327e-5
GO:0072404	signal transduction involved in G1/S transition checkpoint	3.817012e-5
GO:0048844	artery morphogenesis	3.891932e-5
GO:0071779	G1/S transition checkpoint	3.986481e-5
GO:0042256	mature ribosome assembly	4.213915e-5
GO:0070588	calcium ion transmembrane transport	4.299489e-5
GO:0001709	cell fate determination	4.428402e-5
GO:0014048	regulation of glutamate secretion	4.514489e-5
GO:0021979	hypothalamus cell differentiation	4.595072e-5
GO:0048806	genitalia development	4.605886e-5
GO:0002328	pro-B cell differentiation	4.615872e-5
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	4.733513e-5
GO:0072262	metanephric glomerular mesangial cell proliferation involved in metanephros development	4.834506e-5
GO:0001656	metanephros development	4.890764e-5
GO:0014049	positive regulation of glutamate secretion	4.908873e-5
GO:0030335	positive regulation of cell migration	4.925922e-5
GO:0050847	progesterone receptor signaling pathway	5.115873e-5
GO:0045428	regulation of nitric oxide biosynthetic process	5.277705e-5
GO:0048745	smooth muscle tissue development	5.356467e-5
GO:0051272	positive regulation of cellular component movement	5.457603e-5
GO:0071482	cellular response to light stimulus	5.556614e-5
GO:0061005	cell differentiation involved in kidney development	5.871835e-5
GO:0009790	embryo development	5.955244e-5
GO:0032024	positive regulation of insulin secretion	5.956028e-5
GO:0040017	positive regulation of locomotion	6.348060e-5
GO:0035295	tube development	6.407206e-5
GO:0010594	regulation of endothelial cell migration	6.449689e-5
GO:0007442	hindgut morphogenesis	6.457863e-5
GO:0002793	positive regulation of peptide secretion	6.730159e-5
GO:0043030	regulation of macrophage activation	7.136914e-5
GO:0090361	regulation of platelet-derived growth factor production	7.164902e-5
GO:0030510	regulation of BMP signaling pathway	7.225169e-5
GO:0072104	glomerular capillary formation	7.264844e-5
GO:0033084	regulation of immature T cell proliferation in thymus	7.264844e-5
GO:0072395	signal transduction involved in cell cycle checkpoint	7.720511e-5
GO:0010628	positive regulation of gene expression	8.068883e-5
GO:0034259	negative regulation of Rho GTPase activity	8.202741e-5
GO:0008283	cell proliferation	8.231020e-5
GO:0042706	eye photoreceptor cell fate commitment	8.388661e-5
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	8.429622e-5
GO:0030522	intracellular receptor mediated signaling pathway	8.615512e-5
GO:0043408	regulation of MAPKKK cascade	8.742949e-5
GO:0002687	positive regulation of leukocyte migration	9.251402e-5
GO:0060973	cell migration involved in heart development	9.317577e-5
GO:0001934	positive regulation of protein phosphorylation	9.350654e-5
GO:0090304	nucleic acid metabolic process	9.383085e-5
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	9.499853e-5
GO:0014066	regulation of phosphatidylinositol 3-kinase cascade	1.013476e-4
GO:0060056	mammary gland involution	1.015472e-4
GO:0021955	central nervous system neuron axonogenesis	1.020738e-4
GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway	1.039786e-4
GO:0001997	positive regulation of the force of heart contraction by epinephrine-norepinephrine	1.041417e-4
GO:0031575	mitotic cell cycle G1/S transition checkpoint	1.079319e-4
GO:0009416	response to light stimulus	1.080987e-4
GO:0021965	spinal cord ventral commissure morphogenesis	1.134773e-4
GO:0030574	collagen catabolic process	1.158178e-4
GO:0070848	response to growth factor stimulus	1.192242e-4
GO:0032844	regulation of homeostatic process	1.192383e-4
GO:0072239	metanephric glomerulus vasculature development	1.200111e-4
GO:0048661	positive regulation of smooth muscle cell proliferation	1.217824e-4
GO:0048259	regulation of receptor-mediated endocytosis	1.293710e-4
GO:0045626	negative regulation of T-helper 1 cell differentiation	1.306400e-4
GO:0060689	cell differentiation involved in salivary gland development	1.380733e-4
GO:0001985	negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure	1.380733e-4
GO:0051173	positive regulation of nitrogen compound metabolic process	1.399968e-4
GO:0006805	xenobiotic metabolic process	1.432242e-4
GO:0010557	positive regulation of macromolecule biosynthetic process	1.484697e-4
GO:0043009	chordate embryonic development	1.510787e-4
GO:0042220	response to cocaine	1.519714e-4
GO:0072102	glomerulus morphogenesis	1.535272e-4
GO:0016571	histone methylation	1.556846e-4
GO:2000177	regulation of neural precursor cell proliferation	1.567744e-4
GO:0033083	regulation of immature T cell proliferation	1.628153e-4
GO:0021915	neural tube development	1.633032e-4
GO:0060279	positive regulation of ovulation	1.689292e-4
GO:0060563	neuroepithelial cell differentiation	1.698544e-4
GO:0050673	epithelial cell proliferation	1.734586e-4
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	1.755296e-4
GO:0035710	CD4-positive, alpha-beta T cell activation	1.792943e-4
GO:0033092	positive regulation of immature T cell proliferation in thymus	1.812067e-4
GO:0002376	immune system process	1.832936e-4
GO:0072422	signal transduction involved in DNA damage checkpoint	1.838260e-4
GO:0051247	positive regulation of protein metabolic process	1.864412e-4
GO:0010001	glial cell differentiation	1.889614e-4
GO:0061036	positive regulation of cartilage development	1.972951e-4
GO:0051383	kinetochore organization	2.045213e-4
GO:0071622	regulation of granulocyte chemotaxis	2.080826e-4
GO:0001817	regulation of cytokine production	2.089155e-4
GO:0045137	development of primary sexual characteristics	2.128874e-4
GO:0060341	regulation of cellular localization	2.152660e-4
GO:0009607	response to biotic stimulus	2.220682e-4
GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint	2.231802e-4
GO:0072179	nephric duct formation	2.306208e-4
GO:0061004	pattern specification involved in kidney development	2.306208e-4
GO:0051382	kinetochore assembly	2.341173e-4
GO:0034644	cellular response to UV	2.344827e-4
GO:0001978	regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback	2.370391e-4
GO:0003357	noradrenergic neuron differentiation	2.370478e-4
GO:0015732	prostaglandin transport	2.376636e-4
GO:0035112	genitalia morphogenesis	2.401393e-4
GO:0048389	intermediate mesoderm development	2.407105e-4
GO:0072098	anterior/posterior pattern specification involved in kidney development	2.407105e-4
GO:0035441	cell migration involved in vasculogenesis	2.407105e-4
GO:0014909	smooth muscle cell migration	2.407105e-4
GO:0033598	mammary gland epithelial cell proliferation	2.461777e-4
GO:0035993	deltoid tuberosity development	2.512586e-4
GO:2000758	positive regulation of peptidyl-lysine acetylation	2.534958e-4
GO:0014904	myotube cell development	2.542904e-4
GO:0010740	positive regulation of intracellular protein kinase cascade	2.580326e-4
GO:0046660	female sex differentiation	2.676437e-4
GO:0032963	collagen metabolic process	2.732133e-4
GO:0034260	negative regulation of GTPase activity	2.781823e-4
GO:0032259	methylation	2.805996e-4
GO:0006139	nucleobase-containing compound metabolic process	2.837593e-4
GO:0048630	skeletal muscle tissue growth	2.839239e-4
GO:0035910	ascending aorta morphogenesis	2.841667e-4
GO:2000761	positive regulation of N-terminal peptidyl-lysine acetylation	2.841667e-4
GO:0050863	regulation of T cell activation	2.880251e-4
GO:0045055	regulated secretory pathway	3.032218e-4
GO:0032202	telomere assembly	3.049204e-4
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	3.104582e-4
GO:0043299	leukocyte degranulation	3.117601e-4
GO:0048483	autonomic nervous system development	3.129036e-4
GO:0043367	CD4-positive, alpha-beta T cell differentiation	3.131063e-4
GO:2000505	regulation of energy homeostasis	3.276409e-4
GO:0071635	negative regulation of transforming growth factor beta production	3.317911e-4
GO:0043587	tongue morphogenesis	3.343779e-4
GO:0009792	embryo development ending in birth or egg hatching	3.356456e-4
GO:0050867	positive regulation of cell activation	3.358028e-4
GO:0002444	myeloid leukocyte mediated immunity	3.399791e-4
GO:0071285	cellular response to lithium ion	3.417199e-4
GO:0032689	negative regulation of interferon-gamma production	3.417199e-4
GO:0045893	positive regulation of transcription, DNA-dependent	3.508466e-4
GO:0072180	mesonephric duct morphogenesis	3.519239e-4
GO:0061056	sclerotome development	3.519239e-4
GO:0034284	response to monosaccharide stimulus	3.526689e-4
GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine	3.673643e-4
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	3.673956e-4
GO:0030316	osteoclast differentiation	3.696875e-4
GO:0006807	nitrogen compound metabolic process	3.703582e-4
GO:0016569	covalent chromatin modification	3.766927e-4
GO:0044060	regulation of endocrine process	3.774696e-4
GO:0048519	negative regulation of biological process	3.795634e-4
GO:0034767	positive regulation of ion transmembrane transport	3.826883e-4
GO:0045453	bone resorption	3.857629e-4
GO:0050798	activated T cell proliferation	3.869887e-4
GO:0010460	positive regulation of heart rate	3.879912e-4
GO:0072175	epithelial tube formation	3.941528e-4
GO:0009314	response to radiation	3.953574e-4
GO:0072224	metanephric glomerulus development	4.034059e-4
GO:0015746	citrate transport	4.054124e-4
GO:0071397	cellular response to cholesterol	4.099538e-4
GO:0032835	glomerulus development	4.165057e-4
GO:0032908	regulation of transforming growth factor beta1 production	4.171190e-4
GO:0018022	peptidyl-lysine methylation	4.228422e-4
GO:0042772	DNA damage response, signal transduction resulting in transcription	4.322274e-4
GO:0040007	growth	4.366948e-4
GO:0051973	positive regulation of telomerase activity	4.428039e-4
GO:0040011	locomotion	4.490857e-4
GO:0048505	regulation of timing of cell differentiation	4.677047e-4
GO:0007493	endodermal cell fate determination	4.726803e-4
GO:0007093	mitotic cell cycle checkpoint	4.728029e-4
GO:0051246	regulation of protein metabolic process	4.743410e-4
GO:0050865	regulation of cell activation	4.793636e-4
GO:0045165	cell fate commitment	4.823005e-4
GO:0043069	negative regulation of programmed cell death	4.945357e-4
GO:0048705	skeletal system morphogenesis	4.952319e-4
GO:0071310	cellular response to organic substance	4.955156e-4
GO:0009746	response to hexose stimulus	4.977438e-4
GO:0050870	positive regulation of T cell activation	5.007771e-4
GO:0033091	positive regulation of immature T cell proliferation	5.036992e-4
GO:0030217	T cell differentiation	5.161752e-4
GO:0044238	primary metabolic process	5.181164e-4
GO:0060157	urinary bladder development	5.227170e-4
GO:0045765	regulation of angiogenesis	5.237150e-4
GO:0048010	vascular endothelial growth factor receptor signaling pathway	5.346885e-4
GO:0032268	regulation of cellular protein metabolic process	5.387036e-4
GO:0033240	positive regulation of cellular amine metabolic process	5.403915e-4
GO:0048771	tissue remodeling	5.422946e-4
GO:0071624	positive regulation of granulocyte chemotaxis	5.439544e-4
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	5.439544e-4
GO:0021952	central nervous system projection neuron axonogenesis	5.554811e-4
GO:0045161	neuronal ion channel clustering	5.561752e-4
GO:0009191	ribonucleoside diphosphate catabolic process	5.638205e-4
GO:0060993	kidney morphogenesis	5.691414e-4
GO:0003057	regulation of the force of heart contraction by chemical signal	5.818567e-4
GO:0006508	proteolysis	5.836762e-4
GO:0071901	negative regulation of protein serine/threonine kinase activity	5.879872e-4
GO:0070647	protein modification by small protein conjugation or removal	5.918400e-4
GO:0006659	phosphatidylserine biosynthetic process	5.927551e-4
GO:0002521	leukocyte differentiation	6.064035e-4
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	6.065688e-4
GO:0006928	cellular component movement	6.099178e-4
GO:0090185	negative regulation of kidney development	6.118767e-4
GO:0060242	contact inhibition	6.118767e-4
GO:0043066	negative regulation of apoptosis	6.186869e-4
GO:0051094	positive regulation of developmental process	6.226482e-4
GO:0045333	cellular respiration	6.251594e-4
GO:0043201	response to leucine	6.280501e-4
GO:0044259	multicellular organismal macromolecule metabolic process	6.299928e-4
GO:0010350	cellular response to magnesium starvation	6.393186e-4
GO:0072234	metanephric nephron tubule development	6.434808e-4
GO:0016572	histone phosphorylation	6.507770e-4
GO:0010157	response to chlorate	6.558210e-4
GO:0045964	positive regulation of dopamine metabolic process	6.558210e-4
GO:0046632	alpha-beta T cell differentiation	6.686420e-4
GO:0021510	spinal cord development	6.782078e-4
GO:0044027	hypermethylation of CpG island	6.827751e-4
GO:2000543	positive regulation of gastrulation	7.070890e-4
GO:0072170	metanephric tubule development	7.098633e-4
GO:0031399	regulation of protein modification process	7.234057e-4
GO:0060562	epithelial tube morphogenesis	7.276214e-4
GO:0009743	response to carbohydrate stimulus	7.367581e-4
GO:0000956	nuclear-transcribed mRNA catabolic process	7.372406e-4
GO:0048870	cell motility	7.524240e-4
GO:0001838	embryonic epithelial tube formation	7.821015e-4
GO:0043113	receptor clustering	7.871766e-4
GO:0003309	type B pancreatic cell differentiation	7.880894e-4
GO:0060947	cardiac vascular smooth muscle cell differentiation	8.163871e-4
GO:0016331	morphogenesis of embryonic epithelium	8.183478e-4
GO:0046631	alpha-beta T cell activation	8.319777e-4
GO:0009617	response to bacterium	8.558914e-4
GO:0035162	embryonic hemopoiesis	8.572849e-4
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	8.700726e-4
GO:0034764	positive regulation of transmembrane transport	8.722408e-4
GO:0033238	regulation of cellular amine metabolic process	8.757551e-4
GO:0009749	response to glucose stimulus	8.796634e-4
GO:0061035	regulation of cartilage development	8.848656e-4
GO:0010941	regulation of cell death	8.944379e-4
GO:0040034	regulation of development, heterochronic	9.085317e-4
GO:0021953	central nervous system neuron differentiation	9.094797e-4
GO:0032912	negative regulation of transforming growth factor beta2 production	9.139054e-4
GO:0090196	regulation of chemokine secretion	9.139054e-4
GO:0048662	negative regulation of smooth muscle cell proliferation	9.366968e-4
GO:0072207	metanephric epithelium development	9.465537e-4
GO:0048523	negative regulation of cellular process	9.483327e-4
GO:0071900	regulation of protein serine/threonine kinase activity	9.489522e-4
GO:0051150	regulation of smooth muscle cell differentiation	9.645945e-4
GO:0032314	regulation of Rac GTPase activity	9.648692e-4
GO:0022407	regulation of cell-cell adhesion	9.873597e-4
GO:0043931	ossification involved in bone maturation	9.876058e-4
GO:0045019	negative regulation of nitric oxide biosynthetic process	9.876058e-4
GO:0072088	nephron epithelium morphogenesis	9.925674e-4
GO:0048793	pronephros development	9.943426e-4
GO:0042063	gliogenesis	9.996593e-4
GO:0071422	succinate transmembrane transport	1.014669e-3
GO:0070349	positive regulation of brown fat cell proliferation	1.014669e-3
GO:0002642	positive regulation of immunoglobulin biosynthetic process	1.014669e-3
GO:0016139	glycoside catabolic process	1.014669e-3
GO:0033627	cell adhesion mediated by integrin	1.022953e-3
GO:0090197	positive regulation of chemokine secretion	1.030169e-3
GO:0048539	bone marrow development	1.030169e-3
GO:0071479	cellular response to ionizing radiation	1.036776e-3
GO:0016570	histone modification	1.046908e-3
GO:0009134	nucleoside diphosphate catabolic process	1.054717e-3
GO:0046826	negative regulation of protein export from nucleus	1.058576e-3
GO:0070625	zymogen granule exocytosis	1.086423e-3
GO:0021954	central nervous system neuron development	1.095904e-3
GO:0042769	DNA damage response, detection of DNA damage	1.107797e-3
GO:0032331	negative regulation of chondrocyte differentiation	1.107797e-3
GO:0048754	branching morphogenesis of a tube	1.120368e-3
GO:0034641	cellular nitrogen compound metabolic process	1.127578e-3
GO:0072218	metanephric ascending thin limb development	1.129569e-3
GO:0072233	metanephric thick ascending limb development	1.129569e-3
GO:0007529	establishment of synaptic specificity at neuromuscular junction	1.129569e-3
GO:0051254	positive regulation of RNA metabolic process	1.135900e-3
GO:0043048	dolichyl monophosphate biosynthetic process	1.137336e-3
GO:0032026	response to magnesium ion	1.149524e-3
GO:0009954	proximal/distal pattern formation	1.153660e-3
GO:2000179	positive regulation of neural precursor cell proliferation	1.170239e-3
GO:0042742	defense response to bacterium	1.172079e-3
GO:0030521	androgen receptor signaling pathway	1.179970e-3
GO:0061053	somite development	1.203634e-3
GO:0060675	ureteric bud morphogenesis	1.210779e-3
GO:0060065	uterus development	1.213168e-3
GO:2000833	positive regulation of steroid hormone secretion	1.217158e-3
GO:0002309	T cell proliferation involved in immune response	1.217158e-3
GO:0018026	peptidyl-lysine monomethylation	1.223116e-3
GO:0048645	organ formation	1.238204e-3
GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation	1.245346e-3
GO:0055015	ventricular cardiac muscle cell development	1.251700e-3
GO:0009410	response to xenobiotic stimulus	1.253058e-3
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	1.274237e-3
GO:0001938	positive regulation of endothelial cell proliferation	1.279703e-3
GO:0007167	enzyme linked receptor protein signaling pathway	1.286305e-3
GO:0043067	regulation of programmed cell death	1.286999e-3
GO:0048546	digestive tract morphogenesis	1.291619e-3
GO:0060525	prostate glandular acinus development	1.292397e-3
GO:0072177	mesonephric duct development	1.302323e-3
GO:0031016	pancreas development	1.303802e-3
GO:0060004	reflex	1.314706e-3
GO:0042129	regulation of T cell proliferation	1.322317e-3
GO:0060736	prostate gland growth	1.327711e-3
GO:0007218	neuropeptide signaling pathway	1.337447e-3
GO:0030325	adrenal gland development	1.346659e-3
GO:0002696	positive regulation of leukocyte activation	1.351618e-3
GO:0009887	organ morphogenesis	1.370474e-3
GO:0010470	regulation of gastrulation	1.370729e-3
GO:0034755	iron ion transmembrane transport	1.375213e-3
GO:0031657	regulation of cyclin-dependent protein kinase activity involved in G1/S	1.376241e-3
GO:0048619	embryonic hindgut morphogenesis	1.387272e-3